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A p53 defect sensitizes various stages of B cell development to lymphomagenesis in mice carrying an IgH 3' regulatory region-driven c-myc transgene.
Rémi Fiancette
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Pauline Rouaud
,
Christelle Vincent-Fabert
,
Brice Laffleur
,
Virginie Magnone
Article dans une revue
hal-00696493v1
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Genetic background modulates susceptibility to oncogen-driven proliferation and lymphoma occurrence in mice carrying a deregulated c-myc transgene.
Christelle Vincent-Fabert
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Rémi Fiancette
,
Véronique Truffinet
,
Nadine Cogné
,
Michel Cogné
Article dans une revue
hal-00514240v1
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The 3' IgH locus control region is sufficient to deregulate a c-myc transgene and promote mature B cell malignancies with a predominant Burkitt-like phenotype.
Véronique Truffinet
,
Eric Pinaud
,
Nadine Cogné
,
Barbara Petit
,
Laurence Guglielmi
Journal of Immunology, 2007, 179 (9), pp.6033-6042
Article dans une revue
hal-00181178v1
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Light chain inclusion permits terminal B cell differentiation and does not necessarily result in autoreactivity.
Christophe Sirac
,
Claire Carrion
,
Sophie Duchez
,
Isabelle Comte
,
Michel Cogné
Proceedings of the National Academy of Sciences of the United States of America, 2006, 103 (20), pp.7747-52. ⟨10.1073/pnas.0509121103⟩
Article dans une revue
hal-00073857v1
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Combination of 3' and 5' IgH regulatory elements mimics the B-specific endogenous expression pattern of IgH genes from pro-B cells to mature B cells in a transgenic mouse model.
Laurence Guglielmi
,
Marc Le Bert
,
Isabelle Comte
,
Marie Laure Dessain
,
Mireille Drouet
Article dans une revue
hal-00023378v1
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Insulators to improve expression of a 3(')IgH LCR-driven reporter gene in transgenic mouse models.
Laurence Guglielmi
,
Marc Le Bert
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Véronique Truffinet
,
Michel Cogné
,
Yves Denizot
Article dans une revue
hal-00023524v1
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