Michel Cogné

Publications

Article dans une revue (152)

Genetic deregulation of REL in germinal center B cells induces generation of a pool of lymphoma precursor cells Léa Prévaud,Karima Ferhat,Dilara Sensoy,Ophélie Teteau,Tiffany Marchiolet al. Blood Advances, 2025, 9 (15), pp.3676-3688. ⟨10.1182/bloodadvances.2023012166⟩ Article dans une revue hal-05247184v1
Using the iCasp9 suicide strategy to control the growth and function of genome-edited B cells with redirected antigen specificity Jenny Leonard,Marine Cahen,Anne-Laure Tanguy,Laurent Deleurme,Natsuko Uedaet al. Molecular Therapy: Oncology, 2025, 33 (4), pp.201104. ⟨10.1016/j.omton.2025.201104⟩ Article dans une revue hal-05454277v1
DIS3 licenses B cells for plasma cell differentiation in humans Emma Miglierina,Julien Bouder,Delfina Ordanoska,Maïwenn Pineau,Simon Leonardet al. Cellular and molecular immunology, 2025, 23 (1), pp.31-47. ⟨10.1038/s41423-025-01369-5⟩ Article dans une revue hal-05417577v1
NGFR regulates stromal cell activation in germinal centers Alberto Hernández-Barranco,Vanesa Santos,Marina S Mazariegos,Eduardo Caleiras,Laura Noguéset al. Cell Reports, 2024, Cell Reports, 43 (2), pp.113705. ⟨10.1016/j.celrep.2024.113705⟩ Article dans une revue hal-04444626v1
Single-hit genome editing optimized for maturation in B cells redirects their specificity toward tumor antigens Natsuko Ueda,Marine Cahen,Jenny Leonard,Laurent Deleurme,Stéphane Dreanoet al. Scientific Reports, 2024, 14 (1), pp.22432. ⟨10.1038/s41598-024-74005-3⟩ Article dans une revue hal-04723581v1
Neutrophil phenotype, effector functions, and microbicidal activity in patients with SARS-CoV-2-associated ARDS Quentin Quelven,Murielle Grégoire,Valentin Coirier,Arnaud Gacouin,Simon Le Gallouet al. Journal of Leukocyte Biology, 2024, 117 (1), pp.qiae195. ⟨10.1093/jleuko/qiae195⟩ Article dans une revue hal-04721254v1
Attempts to evaluate locus suicide recombination and its potential role in B cell negative selection in the mouse Nicolas Denis-Lagache,Christelle Oblet,Tiffany Marchiol,Audrey Baylet,Ophélie Teteauet al. Frontiers in Immunology, 2023, 14, pp.1155906. ⟨10.3389/fimmu.2023.1155906⟩ Article dans une revue hal-04167864v1
Unique repetitive nucleic acid structures mirror switch regions in the human IgH locus Ophelie Deze,Delfina Ordanoska,Delphine Rossille,Emma Miglierina,Brice Laffleuret al. Biochimie, 2023, 214, pp.167-175. ⟨10.1016/j.biochi.2023.08.017⟩ Article dans une revue hal-04212710v1
Demultiplexing Ig repertoires by parallel mRNA/DNA sequencing shows major differential alterations in severe COVID-19 Virginie Pascal,Marine Dupont,Paco de Rouault,David Rizzo,Delphine Rossilleet al. iScience, 2023, 26 (3), pp.106260. ⟨10.1016/j.isci.2023.106260⟩ Article dans une revue inserm-04041493v1
Roles of G4-DNA and G4-RNA in Class Switch Recombination and Additional Regulations in B-Lymphocytes Ophelie Deze,Brice Laffleur,Michel Cogné Molecules, 2023, 28 (3), ⟨10.3390/molecules28031159⟩ Article dans une revue hal-04059303v1
RNA-based immunoglobulin repertoire sequencing is a new tool for the management of monoclonal gammopathy of renal (kidney) significance Vincent Javaugue,Virginie Pascal,Sébastien Bender,Sarah Nasraddine,Mathilde Dargeloset al. Kidney International, 2022, 101 (2), pp.331-337. ⟨10.1016/j.kint.2021.10.017⟩ Article dans une revue hal-03482172v1
Beneficial effects of citrulline enteral administration on sepsis-induced T cell mitochondrial dysfunction Florian Reizine,Murielle Grégoire,Mathieu Lesouhaitier,Valentin Coirier,Juliette Gauthieret al. Proceedings of the National Academy of Sciences of the United States of America, 2022, 119 (8), pp.e2115139119. ⟨10.1073/pnas.2115139119⟩ Article dans une revue hal-03594344v1
Targeting IgE polyadenylation signal with antisense oligonucleotides decreases IgE secretion and plasma cell viability Anne Marchalot,Catherine Horiot,Jean-Marie Lambert,Claire Carrion,Christelle Obletet al. Journal of Allergy and Clinical Immunology, 2022, 149 (5), pp.1795-1801. ⟨10.1016/j.jaci.2021.09.039⟩ Article dans une revue hal-03482143v1
Neutralizing antibodies against SARS-CoV-2 variants following mRNA booster vaccination in adults older than 65 years Christine Durier,Laetitia Ninove,Maeva Lefebvre,Anne Radenne,Corinne Desaintet al. Scientific Reports, 2022, 12 (1), pp.20373. ⟨10.1038/s41598-022-24409-w⟩ Article dans une revue hal-04119081v1
Editorial: Germinal Centers in Lymphoid and Non-Lymphoid Tissues: Adaptive and Evolving Structures Michel Cogné,Thierry Fest,Said Aoufouchi Frontiers in Immunology, 2022, 13, pp.880733. ⟨10.3389/fimmu.2022.880733⟩ Article dans une revue hal-03798529v2
Du self-control lymphocytaire B aux abords thérapeutiques, quelles voies « B-intrinsèques » pour tempérer les réponses et la mémoire IgE ? Michel Cogné,Z. Dalloul,O. Dézé,M. Le Goff,S. Thomaset al. Revue Française d'Allergologie, 2022, 62 (5), pp.482-491. ⟨10.1016/j.reval.2021.10.012⟩ Article dans une revue hal-03520779v1
Distinct B-Cell Specific Transcriptional Contexts of the BCL2 Oncogene Impact Pre-Malignant Development in Mouse Models Lina Zawil,Tiffany Marchiol,Baptiste Brauge,Alexis Saintamand,Claire Carrionet al. Cancers, 2022, 14 (21), pp.5337. ⟨10.3390/cancers14215337⟩ Article dans une revue hal-03888678v1
Homéostasie de la réponse IgA et microbiote Virginie Pascal,Margaux Hiblot,Batoul Wehbi,Jean-Claude Aldigier,Michel Cogné Médecine/Sciences, 2021, 37 (1), pp.35-40. ⟨10.1051/medsci/2020258⟩ Article dans une revue hal-03120839v1
Venoarterial extracorporeal membrane oxygenation induces early immune alterations Aurelien Frerou,Mathieu Lesouhaitier,Murielle Gregoire,Fabrice Uhel,Arnaud Gacouinet al. Critical Care, 2021, 25 (1), pp.9. ⟨10.1186/s13054-020-03444-x⟩ Article dans une revue hal-03134918v1
IgH 3’ regulatory region increases ectopic class switch recombination Sandrine Le Noir,Amélie Bonaud,Bastien Hervé,Audrey Baylet,François Boyeret al. PLoS Genetics, 2021, 17 (2), pp.e1009288. ⟨10.1371/journal.pgen.1009288⟩ Article dans une revue hal-03371044v1
Bromodomain and extraterminal (BET) protein inhibition of IgG/IgE production in murine B cells is counter-balanced by a strong Th2 bias Zeinab Dalloul,Marie Best,Pauline Chenuet,Iman Dalloul,Sandrine Le Noiret al. Clinical and Translational Immunology, 2021, 10 (6), pp.e1280. ⟨10.1002/cti2.1280⟩ Article dans une revue hal-03283657v1
Transcription/Replication Conflicts in Tumorigenesis and Their Potential Role as Novel Therapeutic Targets in Multiple Myeloma Laure Dutrieux,Yea-Lih Lin,Malik Lutzmann,Raphaël Rodriguez,Michel Cognéet al. Cancers, 2021, 13 (15), pp.3755. ⟨10.3390/cancers13153755⟩ Article dans une revue hal-03365519v1
Comparative immune profiling of acute respiratory distress syndrome patients with or without SARS-CoV-2 infection Mikael Roussel,Juliette Ferrant,Florian Reizine,Simon Le Gallou,Joelle Dulonget al. Cell Reports Medicine, 2021, 2 (6), pp.100291. ⟨10.1016/j.xcrm.2021.100291⟩ Article dans une revue hal-04872972v2
Immunotherapy perspectives in the new era of B-cell editing Natsuko Ueda,Marine Cahen,Yannic Danger,Jérôme Moreaux,Christophe Siracet al. Blood Advances, 2021, 5 (6), pp.1770-1779. ⟨10.1182/bloodadvances.2020003792⟩ Article dans une revue hal-03202338v1
Fam72a enforces error-prone DNA repair during antibody diversification Mélanie Rogier,Jacques Moritz,Isabelle Robert,Chloé Lescale,Vincent Heyeret al. Nature, 2021, 600 (7888), pp.329-333. ⟨10.1038/s41586-021-04093-y⟩ Article dans une revue hal-03451745v1
Impact of HIV-1 Vpr manipulation of the DNA repair enzyme UNG2 on B lymphocyte class switch recombination Patrick Eldin,Sophie Péron,Anastasia Galashevskaya,Nicolas Denis-Lagache,Michel Cognéet al. Journal of Translational Medicine, 2020, 18 (1), ⟨10.1186/s12967-020-02478-7⟩ Article dans une revue hal-02914967v1
An Engineered Human Fc Domain that Behaves like a pH-Toggle Switch for Ultra-Long Circulation Persistence Tae Hyun Kang,Chang-Han Lee,Tae Hyun Kang,Ophélie Godon,Makiko Watanabeet al. Nature Communications, 2019, 10 (1), pp.5031. ⟨10.1038/s41467-019-13108-2⟩ Article dans une revue pasteur-02448624v1
IgH locus suicide recombination does not depend on NHEJ in contrast to CSR in B cells Nour Ghazzaui,Hussein Issaoui,Ophélie Alyssa Martin,Alexis Saintamand,Yves Denizotet al. Cellular and molecular immunology, 2019, 16 (2), pp.201-202. ⟨10.1038/s41423-018-0172-2⟩ Article dans une revue hal-02343984v1
Locus suicide recombination actively occurs on the functionally rearranged IgH allele in B- cells from inflamed human lymphoid tissues Iman Dalloul,François Boyer,Zeinab Dalloul,Amandine Pignarre,Gersende Caronet al. PLoS ONE, 2019, 15 (6), pp.e1007721. ⟨10.1371/journal.pgen.1007721⟩ Article dans une revue inserm-02273760v1
Mesangial Deposition Can Strongly Involve Innate-Like IgA Molecules Lacking Affinity Maturation Batoul Wehbi,Christelle Oblet,François Boyer,Arnaud Huard,Anne Druilheet al. Journal of the American Society of Nephrology, 2019, 30 (7), pp.1238-1249. ⟨10.1681/ASN.2018111089⟩ Article dans une revue hal-02361794v1
Physiological and druggable skipping of immunoglobulin variable exons in plasma cells Mohamad Omar Ashi,Nivine Srour,Jean-Marie Lambert,Anne Marchalot,Ophélie Martinet al. Cellular and molecular immunology, 2018, ⟨10.1038/s41423-018-0160-6⟩ Article dans une revue hal-02048156v1
Mediator contributes to IgH locus VDJ rearrangements by promoting usage of most distal V segments Iman Dalloul,Zeinab Dalloul,Sandrine Le Noir,François Boyer,Bernardo Reina-San-Martinet al. Cellular and molecular immunology, 2018, ⟨10.1038/s41423-018-0175-z⟩ Article dans une revue hal-02343957v1
Comprehensive molecular characterization of a heavy chain deposition disease case Sébastien Bender,Maria Victoria Ayala,Vincent Javaugue,Amélie Bonaud,Michel Cognéet al. Haematologica, 2018, 103 (11), pp.e557-e560. ⟨10.3324/haematol.2018.196113⟩ Article dans une revue hal-02343962v1
&lt;i&gt;PAX5A&lt;/i&gt; and &lt;i&gt;PAX5B&lt;/i&gt; isoforms are both efficient to drive B cell differentiation Charlotte Cresson,Sophie Péron,Laura Jamrog,Nelly Rouquié,Nais Pradeet al. Oncotarget, 2018, 9 (67), ⟨10.18632/oncotarget.26003⟩ Article dans une revue hal-02343994v1
&lt;i&gt;PAX5A&lt;/i&gt; and &lt;i&gt;PAX5B&lt;/i&gt; isoforms are both efficient to drive B cell differentiation Charlotte Cresson,Sophie Péron,Laura Jamrog,Nelly Rouquié,Nais Pradeet al. Oncotarget, 2018, 9 (67), pp.32841-32854. ⟨10.18632/oncotarget.26003⟩ Article dans une revue hal-02566158v1
Detecting Rare AID-Induced Mutations in B-Lineage Oncogenes from High-Throughput Sequencing Data Using the Detection of Minor Variants by Error Correction Method Ophélie Alyssa Martin,Armand Garot,Sandrine Le Noir,Jean-Claude Aldigier,Michel Cognéet al. Journal of Immunology, 2018, 201 (3), pp.950-956. ⟨10.4049/jimmunol.1800203⟩ Article dans une revue hal-02344000v1
G-quadruplex DNA targeting alters class-switch recombination in B cells and attenuates allergic inflammation Zeinab Dalloul,Pauline Chenuet,Iman Dalloul,François Boyer,Jean-Claude Aldigieret al. Journal of Allergy and Clinical Immunology, 2018, 142 (4), pp.1352-1355. ⟨10.1016/j.jaci.2018.06.011⟩ Article dans une revue hal-02343989v1
Animal models of monoclonal immunoglobulin-related renal diseases Christophe Sirac,Guillermo Herrera,Paul Sanders,Vecihi Batuman,Sébastien Benderet al. Nature Reviews Nephrology, 2018, 14 (4), pp.246-264. ⟨10.1038/nrneph.2018.8⟩ Article dans une revue hal-02344013v1
Characterization of human FCRL4-positive B cells Michel Jourdan,Nicolas Robert,Maïlys Cren,Coraline Thibaut,Christophe Duperrayet al. PLoS ONE, 2017, 12 (6), pp.e0179793. ⟨10.1371/journal.pone.0179793⟩ Article dans une revue hal-01560458v1
Unravelling the immunopathological mechanisms of heavy chain deposition disease with implications for clinical management Frank Bridoux,Vincent Javaugue,Sébastien Bender,Fannie Leroy,Pierre Aucouturieret al. Kidney International, 2017, 91 (2), pp.423-434. ⟨10.1016/j.kint.2016.09.004⟩ Article dans une revue hal-02364147v1
Eμ and 3'RR IgH enhancers show hierarchic unilateral dependence in mature B-cells Alexis Saintamand,Christelle Vincent-Fabert,Marie Marquet,Nour Ghazzaui,Virginie Magnoneet al. Scientific Reports, 2017, 7 (1), pp.442. ⟨10.1038/s41598-017-00575-0⟩ Article dans une revue hal-01517051v1
Deciphering the importance of the palindromic architecture of the immunoglobulin heavy-chain 3’ regulatory region Alexis Saintamand,Christelle Vincent-Fabert,Armand Garot,Pauline Rouaud,Zéliha Orucet al. Nature Communications, 2016, 7, pp.10730. ⟨10.1038/ncomms10730⟩ Article dans une revue hal-01442466v1
First Membrane Proximal External Region-Specific Anti-HIV1 Broadly Neutralizing Monoclonal IgA1 Presenting Short CDRH3 and Low Somatic Mutations. Fahd Benjelloun,Zéliha Oruc,Nicole M. Thielens,Bernard Verrier,Gael Champieret al. Journal of Immunology, 2016, 197 (5), pp.1979-88. ⟨10.4049/jimmunol.1600309⟩ Article dans une revue hal-01356638v1
A plasma cell differentiation quality control ablates B cell clones with biallelic Ig rearrangements and truncated Ig production Nivine Srour,Guillaume Chemin,Aurélien Tinguely,Mohamad Omar Ashi,Zéliha Orucet al. Journal of Experimental Medicine, 2016, 213 (1), pp.109-122. ⟨10.1084/jem.20131511⟩ Article dans une revue hal-01501807v1
Impaired Lysosomal Function Underlies Monoclonal Light Chain–Associated Renal Fanconi Syndrome Alessandro Luciani,Christophe Sirac,Sara Terryn,Vincent Javaugue,Jenny Ann Prangeet al. Journal of the American Society of Nephrology, 2016, 27 (7), pp.2049-2061. ⟨10.1681/ASN.2015050581⟩ Article dans une revue hal-02364437v1
Loss of the HVEM Tumor Suppressor in Lymphoma and Restoration by Modified CAR-T Cells Michael Boice,Darin Salloum,Frédéric Mourcin,Viraj Sanghvi,Rada Aminet al. Cell, 2016, 167 (2), pp.405-418 e13. ⟨10.1016/j.cell.2016.08.032⟩ Article dans une revue hal-01405853v1
IgA Structure Variations Associate with Immune Stimulations and IgA Mesangial Deposition Zéliha Oruc,Christelle Oblet,Ahmed Boumédiène,Anne Druilhe,Virginie Pascalet al. Journal of the American Society of Nephrology, 2016, 27 (9), pp.2748-2761. ⟨10.1681/ASN.2015080911⟩ Article dans une revue hal-01269915v1
Sequential activation and distinct functions for distal and proximal modules within the IgH 3′ regulatory region Armand Garot,Marie Marquet,Alexis Saintamand,Sébastien Bender,Sandrine Le Noiret al. Proceedings of the National Academy of Sciences of the United States of America, 2016, 113 (6), pp.1618-1623. ⟨10.1073/pnas.1514090113⟩ Article dans une revue hal-02364206v1
The contribution of virtual reality to the diagnosis of spatial navigation disorders and to the study of the role of navigational aids: A systematic literature review. Michel Cogné,Mathieu Taillade,Bernard N'Kaoua,Annabelle Tarruella,Evelyne Klingeret al. Annals of Physical and Rehabilitation Medicine, 2016, ⟨10.1016/j.rehab.2015.12.004⟩ Article dans une revue hal-01354011v1
Quand les gènes codant les anticorps s’adjoignent des fragments venus d’autres chromosomes Brice Laffleur,Zeinab Dalloul,Iman Dalloul,Sandrine Le Noir,Michel Cogné Médecine/Sciences, 2016, 32 (8-9), pp.677-680. ⟨10.1051/medsci/20163208006⟩ Article dans une revue hal-02364198v1
Developmental Switch in the Transcriptional Activity of a Long-Range Regulatory Element Fatima-Zohra Braikia,Caroline Conte,Mohamed Moutahir,Yves Denizot,Michel Cognéet al. Molecular and Cellular Biology, 2015, 35 (19), pp.3370-3380. ⟨10.1128/mcb.00509-15⟩ Article dans une revue hal-01501824v1
Self-control for IgE production. Brice Laffleur,Michel Cogné Oncotarget, 2015 Article dans une revue hal-01212546v1
A mouse model recapitulating human monoclonal heavy chain deposition disease evidences the relevance of proteasome inhibitor therapy. Amélie Bonaud,Sébastien Bender,G Touchard,C Lacombe,Nivine Srouret al. Blood, 2015 Article dans une revue hal-01212560v1
Comment on &quot;IgH chain class switch recombination: mechanism and regulation&quot;. Alexis Saintamand,Jc Lecron,Frédéric Morel,Michel Cogné,Yves Denizot Journal of Immunology, 2015 Article dans une revue hal-01212327v1
Self-Restrained B Cells Arise following Membrane IgE Expression Brice Laffleur,Sophie Duchez,Karin Tarte,Nicolas Denis-Lagache,Sophie Péronet al. Cell Reports, 2015, 10 (6), pp.900-909. ⟨10.1016/j.celrep.2015.01.023⟩ Article dans une revue hal-01116949v1
Efficient AID targeting of switch regions is not sufficient for optimal class switch recombination. Amélie Bonaud,Fabien Lechouane,S Le Noir,O Monestier,Michel Cognéet al. Nature Communications, 2015 Article dans une revue hal-01212525v1
The IgH 3' regulatory region governs μ chain transcription in mature B lymphocytes and the B cell fate. Alexis Saintamand,Pauline Rouaud,Armand Garot,Faten Saad,Claire Carrionet al. Oncotarget, 2015 Article dans une revue hal-01212314v1
Elucidation of IgH 3' region regulatory role during class switch recombination via germline deletion. Alexis Saintamand,Pauline Rouaud,Faten Saad,G Rios,Michel Cognéet al. Nature Communications, 2015 Article dans une revue hal-01212563v1
The Eμ enhancer region influences H chain expression and B cell fate without impacting IgVH repertoire and immune response in vivo. Marie Marquet,Armand Garot,Sébastien Bender,Claire Carrion,Pauline Rouaudet al. Journal of Immunology, 2014, 193 (3), pp.1171-83. ⟨10.4049/jimmunol.1302868⟩ Article dans une revue hal-01110453v1
Immunoglobulin genes undergo legitimate repair in human B cells not only after cis- but also frequent trans-class switch recombination. Brice Laffleur,Sylvia M. Bardet,Armand Garot,M Brousse,A Bayletet al. Genes and Immunity, 2014, 15 (5), pp.341-6. ⟨10.1038/gene.2014.25⟩ Article dans une revue hal-01112042v1
The class-specific BCR tonic signal modulates lymphomagenesis in a c-myc deregulation transgenic model. Rada Amin,Abdelghafour Marfak,Céline Pangault,Christelle Oblet,Aurélie Chanutet al. Oncotarget, 2014, 5 (19), pp.8995-9006. ⟨10.18632/oncotarget.2297⟩ Article dans une revue hal-01067143v1
Caractéristiques des IgA promptes à se déposer dans le mésangium J.C. Aldigier,Zéliha Oruc,Christelle Oblet,Ahmed Boumédiène,Alexis Cuvillieret al. Néphrologie & Thérapeutique, 2014, 10 (5), pp.282. ⟨10.1016/j.nephro.2014.07.354⟩ Article dans une revue istex hal-01117015v1
Elucidation of the enigmatic IgD class-switch recombination via germline deletion of the IgH 3' regulatory region Pauline Rouaud,Alexis Saintamand,Faten Saad,Claire Carrion,Sandrine Lecardeuret al. Journal of Experimental Medicine, 2014 Article dans une revue hal-01212566v1
Activation-induced deaminase in B lymphocyte maturation and beyond. Michel Cogné Biomed J, 2013, 36 (6), pp.259-68. ⟨10.4103/2319-4170.113191⟩ Article dans une revue hal-00945344v1
The IgH 3' regulatory region controls somatic hypermutation in germinal center B cells. Pauline Rouaud,Christelle Vincent-Fabert,Alexis Saintamand,Rémi Fiancette,Marie Marquetet al. Journal of Experimental Medicine, 2013, 210 (8), pp.1501-7. ⟨10.1084/jem.20130072⟩ Article dans une revue hal-00903790v1
IGHV gene features and MYD88 L265P mutation separate the three marginal zone lymphoma entities and Waldenström macroglobulinemia/lymphoplasmacytic lymphomas. Nathalie Gachard,M. Parrens,Isabelle Soubeyran,Barbara Petit,A. Marfaket al. Leukemia, 2013, 27 (1), pp.183-9. ⟨10.1038/leu.2012.257⟩ Article dans une revue hal-00779407v1
Abnormal apical-to-basal transport of dietary ovalbumin by secretory IgA stimulates a mucosal Th1 response. J. Abed,C. Lebreton,G. Champier,Alexis Cuvillier,Michel Cognéet al. Mucosal Immunology, 2013, epub ahead of print. ⟨10.1038/mi.2013.49⟩ Article dans une revue hal-00903792v1
Flexible long-range loops in the VH gene region of the Igh locus facilitate the generation of a diverse antibody repertoire. Jasna Medvedovic,Anja Ebert,Hiromi Tagoh,Ido M Tamir,Tanja A Schwickertet al. Immunity, 2013, 39 (2), pp.229-44. ⟨10.1016/j.immuni.2013.08.011⟩ Article dans une revue hal-00903793v1
Enhancers located in heavy chain regulatory region (hs3a, hs1,2, hs3b, and hs4) are dispensable for diversity of VDJ recombination. Pauline Rouaud,Christelle Vincent-Fabert,Rémi Fiancette,Michel Cogné,Eric Pinaudet al. Journal of Biological Chemistry, 2012, 287 (11), pp.8356-60. ⟨10.1074/jbc.M112.341024⟩ Article dans une revue hal-00696502v1
Transglutaminase is essential for IgA nephropathy development acting through IgA receptors. Laureline Berthelot,Christina Papista,Thiago T Maciel,Martine Biarnes-Pelicot,Emilie Tissandieet al. Journal of Experimental Medicine, 2012, 209 (4), pp.793-806. ⟨10.1084/jem.20112005⟩ Article dans une revue hal-00903832v1
B-cell receptor signal strength influences terminal differentiation. Fabien Lechouane,Amélie Bonaud,Laurent Delpy,Stefano Casola,Zéliha Orucet al. European Journal of Immunology, 2012, epub ahead of print. ⟨10.1002/eji.201242912⟩ Article dans une revue hal-00779414v1
Deletion of the α immunoglobulin chain membrane-anchoring region reduces but does not abolish IgA secretion. Rada Amin,Claire Carrion,Catherine Decourt,Eric Pinaud,Michel Cogné Immunology, 2012, 136 (1), pp.54-63. ⟨10.1111/j.1365-2567.2012.03557.x⟩ Article dans une revue hal-00696503v1
Production of human or humanized antibodies in mice. Brice Laffleur,Virginie Pascal,Christophe Sirac,Michel Cogné Methods in Molecular Biology, 2012, 901, pp.149-59. ⟨10.1007/978-1-61779-931-0_9⟩ Article dans une revue hal-00779395v1
[IgH locus suicide recombination, or when B cells surrender!]. Sophie Péron,Brice Laffleur,Nicolas Denis-Lagache,Jeanne Cook-Moreau,Matthieu Fillouxet al. Médecine/Sciences, 2012, 28 (5), pp.551-4. ⟨10.1051/medsci/2012285023⟩ Article dans une revue hal-00779352v1
Specific impairment of proximal tubular cell proliferation by a monoclonal κ light chain responsible for Fanconi syndrome. Chahrazed El Hamel,Jean-Claude Aldigier,Christelle Oblet,Brice Laffleur,Franck Bridouxet al. Nephrology Dialysis Transplantation, 2012, 27 (12), pp.4368-77. ⟨10.1093/ndt/gfs261⟩ Article dans une revue hal-00779410v1
A defect of the INK4-Cdk4 checkpoint and Myc collaborate in blastoid mantle cell lymphoma-like lymphoma formation in mice. Christelle Vincent-Fabert,Rémi Fiancette,Pauline Rouaud,Christel Baudet,Véronique Truffinetet al. American Journal of Pathology, 2012, 180 (4), pp.1688-701. ⟨10.1016/j.ajpath.2012.01.004⟩ Article dans une revue hal-00696495v1
AID-Driven Deletion Causes Immunoglobulin Heavy Chain &quot;Locus Suicide Recombination&quot; in B Cells. Sophie Péron,Brice Laffleur,Nicolas Denis-Lagache,Jeanne Cook-Moreau,Aurélien Tinguelyet al. Science, 2012, epub ahead of print. ⟨10.1126/science.1218692⟩ Article dans une revue hal-00697665v1
Cross talk between immunoglobulin heavy-chain transcription and RNA surveillance during B cell development. Aurélien Tinguely,Guillaume Chemin,Sophie Péron,Christophe Sirac,Stéphane Reynaudet al. Molecular and Cellular Biology, 2012, 32 (1), pp.107-17. ⟨10.1128/MCB.06138-11⟩ Article dans une revue hal-00696497v1
Class-specific effector functions of therapeutic antibodies. Virginie Pascal,Brice Laffleur,Michel Cogné Methods in Molecular Biology, 2012, 901, pp.295-317. ⟨10.1007/978-1-61779-931-0_19⟩ Article dans une revue hal-00779398v1
Anti-CD20 IgA can protect mice against lymphoma development: evaluation of the direct impact of IgA and cytotoxic effector recruitment on CD20 target cells. Virginie Pascal,Brice Laffleur,Arnaud Debin,Armelle Cuvillier,Marjolein van Egmondet al. Haematologica, 2012, 97 (11), pp.1686-94. ⟨10.3324/haematol.2011.061408⟩ Article dans une revue hal-00779391v1
Mantle cell lymphoma-like lymphomas in c-myc-3'RR/p53+/- mice and c-myc-3'RR/Cdk4R24C mice: differential oncogenic mechanisms but similar cellular origin. Pauline Rouaud,Rémi Fiancette,Christelle Vincent-Fabert,Virginie Magnone,Michel Cognéet al. Oncotarget, 2012, 3 (5), pp.586-93 Article dans une revue hal-00779350v1
Polymeric IgA1 controls erythroblast proliferation and accelerates erythropoiesis recovery in anemia. Séverine Coulon,Michaël Dussiot,Damien Grapton,Thiago Trovati Maciel,Pamella Huey Mei Wanget al. Nature Medicine, 2011, 17 (11), pp.1456-65. ⟨10.1038/nm.2462⟩ Article dans une revue hal-00696490v1
Toward understanding renal Fanconi syndrome: step by step advances through experimental models. Christophe Sirac,Franck Bridoux,Marie Essig,Olivier Devuyst,Guy Touchardet al. Contributions to Nephrology, 2011, 169, pp.247-61. ⟨10.1159/000313962⟩ Article dans une revue hal-00696465v1
Strategies to model AL amyloidosis in mice. Christophe Sirac,Sébastien Bender,Arnaud Jaccard,Franck Bridoux,C. Lacombeet al. Amyloid: The Journal of Protein Folding Disorders, 2011, 18 (Suppl 1), pp.45-47. ⟨10.3109/13506129.2011.574354016⟩ Article dans une revue hal-00617188v2
Glycotranscriptome study reveals an enzymatic switch modulating glycosaminoglycan synthesis during B cell development and activation. Sophie Duchez,Virginie Pascal,Nadine Cogné,Chantal Jayat-Vignoles,Raymond Julienet al. European Journal of Immunology, 2011, 41 (12), epub ahead of print. ⟨10.1002/eji.201140865⟩ Article dans une revue hal-00696483v1
The IgH locus 3' regulatory region: pulling the strings from behind. Eric Pinaud,Marie Marquet,Rémi Fiancette,Sophie Péron,Christelle Vincent-Fabertet al. Advances in immunology, 2011, 110, pp.27-70. ⟨10.1016/B978-0-12-387663-8.00002-8⟩ Article dans une revue hal-00696444v1
A p53 defect sensitizes various stages of B cell development to lymphomagenesis in mice carrying an IgH 3' regulatory region-driven c-myc transgene. Rémi Fiancette,Pauline Rouaud,Christelle Vincent-Fabert,Brice Laffleur,Virginie Magnoneet al. Journal of Immunology, 2011, 187 (11), pp.5772-82. ⟨10.4049/jimmunol.1102059⟩ Article dans une revue hal-00696493v1
Similarity of fine specificity of IgA anti-gliadin antibodies between patients with celiac disease and humanized α1KI mice. Daniel Sánchez,Gaël Champier,Armelle Cuvillier,Michel Cogné,Aneta Pekárikováet al. Journal of Agricultural and Food Chemistry, 2011, 59 (7), pp.3092-100. ⟨10.1021/jf1044519⟩ Article dans une revue hal-00696473v1
Glycotranscriptome study reveals an enzymatic switch modulating glycosaminoglycan synthesis during B-cell development and activation Sophie Duchez,Virginie Pascal,Nadine Cogné,Chantal Jayat-Vignoles,Raymond Julienet al. European Journal of Immunology, 2011, 41 (12), pp.3632-3644. ⟨10.1002/eji.201140865⟩ Article dans une revue hal-01211951v1
Polymeric IgA1 controls erythroblast proliferation and accelerates erythropoiesis recovery in anemia. S. Coulon,M. Dussiot,D. Grapton,Trovati Maciel T.,Huey Mei Wang P.et al. Nature Medicine, 2011, 17, pp.1456-1465 Article dans une revue hal-00617557v1
Complexes between nuclear factor-κB p65 and signal transducer and activator of transcription 3 are key actors in inducing activation-induced cytidine deaminase expression and immunoglobulin A production in CD40L plus interleukin-10-treated human blood B cells. S. Lafarge,H. Hamzeh-Cognasse,Y. Richard,B. Pozzetto,Michel Cognéet al. Clinical and Experimental Immunology, 2011, 166 (2), pp.171-83. ⟨10.1111/j.1365-2249.2011.04465.x⟩ Article dans une revue hal-00697663v1
Gammopathy with IgA mesangial deposition provides a monoclonal model of IgA nephritogenicity and offers new insights into its molecular mechanisms. Ahmed Boumédiène,Christelle Oblet,Zéliha Oruc,Sophie Duchez,Willy Morelleet al. Nephrology Dialysis Transplantation, 2011, 26 (12), pp.3930-7. ⟨10.1093/ndt/gfr131⟩ Article dans une revue hal-00696463v1
The IgH 3' regulatory region and its implication in lymphomagenesis. Christelle Vincent-Fabert,Rémi Fiancette,Michel Cogné,Eric Pinaud,Yves Denizot European Journal of Immunology, 2010, 40 (12), pp.3306-11. ⟨10.1002/eji.201040778⟩ Article dans une revue hal-00559583v1
Genomic deletion of the whole IgH 3' regulatory region (hs3a, hs1,2, hs3b, hs4) dramatically affects class switch recombination and Ig secretion to all isotypes. Christelle Vincent-Fabert,Rémi Fiancette,Eric Pinaud,Véronique Truffinet,Nadine Cognéet al. Blood, 2010, epub ahead of print. ⟨10.1182/blood-2010-01-264689⟩ Article dans une revue hal-00514236v1
In vivo redundant function of the 3' IgH regulatory element HS3b in the mouse. Anne-Gaëlle Bébin,Claire Carrion,Marie Marquet,Nadine Cogné,Sandrine Lecardeuret al. Journal of Immunology, 2010, 184 (7), pp.3710-7. ⟨10.4049/jimmunol.0901978⟩ Article dans une revue hal-00514232v1
A myeloma translocation-like model associating CCND1 with the immunoglobulin heavy-chain locus 3' enhancers does not promote by itself B-cell malignancies. Rémi Fiancette,Rada Amin,Véronique Truffinet,Christelle Vincent-Fabert,Nadine Cognéet al. Leukemia Research, 2010, 34 (8), pp.1043-51. ⟨10.1016/j.leukres.2009.11.017⟩ Article dans une revue istex hal-00514237v1
Premature replacement of {micro} with {alpha} immunoglobulin chains impairs lymphopoiesis and mucosal homing but promotes plasma cell maturation. Sophie Duchez,Rada Amin,Nadine Cogné,Laurent Delpy,Christophe Siracet al. Proceedings of the National Academy of Sciences of the United States of America, 2010, epub ahead of print. ⟨10.1073/pnas.0912393107⟩ Article dans une revue hal-00454129v1
Crystal-storing histiocytosis with renal Fanconi syndrome: pathological and molecular characteristics compared with classical myeloma-associated Fanconi syndrome. Chahrazed El Hamel,Antoine Thierry,Patrick Trouillas,Franck Bridoux,Claire Carrionet al. Nephrology Dialysis Transplantation, 2010, 25 (9), pp.2982-90. ⟨10.1093/ndt/gfq129⟩ Article dans une revue istex hal-00514235v1
Multiple RNA surveillance mechanisms cooperate to reduce the amount of nonfunctional Ig kappa transcripts. Guillaume Chemin,Aurélien Tinguely,Christophe Sirac,Fabien Lechouane,Sophie Duchezet al. Journal of Immunology, 2010, 184 (9), pp.5009-17. ⟨10.4049/jimmunol.0902949⟩ Article dans une revue hal-00511941v1
Transgenesis and humanization of murine antibodies. Michel Cogné,Sophie Duchez,Virginie Pascal Médecine/Sciences, 2009, 25 (12), pp.1149-54 Article dans une revue hal-00443792v1
[Physiopathology of bullous pemphigoid] V. Doffoel-Hantz,Michel Cogné,M. Drouet,Agnès Sparsa,J.-M. Bonnetblancet al. Annales de Dermatologie et de Vénéréologie, 2009, 136 (10), pp.740-7; quiz 739, 748. ⟨10.1016/j.annder.2008.10.044⟩ Article dans une revue hal-00452834v1
Uncoupling between Ig somatic hypermutation and oncogene mutation in mouse lymphoma. Christelle Vincent-Fabert,Véronique Truffinet,Rémi Fiancette,Barbara Petit,Nadine Cognéet al. Biochimica et Biophysica Acta - Molecular Cell Research, 2009, 1793 (2), pp.418-26. ⟨10.1016/j.bbamcr.2008.10.011⟩ Article dans une revue istex hal-00363954v1
Ig synthesis and class switching do not require the presence of the hs4 enhancer in the 3' IgH regulatory region. Christelle Vincent-Fabert,Véronique Truffinet,Rémi Fiancette,Nadine Cogné,Michel Cognéet al. Journal of Immunology, 2009, 182 (11), pp.6926-32. ⟨10.4049/jimmunol.0900214⟩ Article dans une revue hal-00443742v1
Genetic background modulates susceptibility to oncogen-driven proliferation and lymphoma occurrence in mice carrying a deregulated c-myc transgene. Christelle Vincent-Fabert,Rémi Fiancette,Véronique Truffinet,Nadine Cogné,Michel Cognéet al. Leukemia Research, 2009, 33 (11), pp.e203-6. ⟨10.1016/j.leukres.2009.05.018⟩ Article dans une revue istex hal-00514240v1
Long-range oncogenic activation of Igh-c-myc translocations by the Igh 3' regulatory region. Monica Gostissa,Catherine T Yan,Julia M Bianco,Michel Cogné,Eric Pinaudet al. Nature, 2009, 462 (7274), pp.803-7. ⟨10.1038/nature08633⟩ Article dans une revue hal-00443754v1
[Physiopathology of herpetiform dermatitis. Current data] V. Doffoel-Hantz,Michel Cogné,Agnès Sparsa,J.-M. Bonnetblanc,Mireille Drouetet al. Annales de Dermatologie et de Vénéréologie, 2008, 135 (11), pp.784-8; quiz 783. ⟨10.1016/j.annder.2008.02.030⟩ Article dans une revue hal-00363969v1
Splenic marginal zone lymphomas and lymphoplasmacytic lymphomas originate from B-cell compartments with two different antigen-exposure histories. M. Parrens,Nathalie Gachard,Barbara Petit,A. Marfak,E. Troadecet al. Leukemia, 2008, 22 (8), pp.1621-4. ⟨10.1038/leu.2008.24⟩ Article dans une revue hal-00364488v1
High-dose melphalan versus melphalan plus dexamethasone for AL amyloidosis. Arnaud Jaccard,Philippe Moreau,Véronique Leblond,Xavier Leleu,Lofti Benboubkeret al. New England Journal of Medicine, 2007, 357 (11), pp.1083-93 Article dans une revue hal-00172895v1
Clinico-biological characteristics of flow cytometry applied to hypersensitivity to NSAIDs. J. Sainte-Laudy,F. Touraine,Ahmed Boumédiène,F. Bonnaud,Michel Cogné Inflammation Research, 2007, 56 Suppl 1, pp.S63-4 Article dans une revue hal-00452811v1
S-S synapsis during class switch recombination is promoted by distantly located transcriptional elements and activation-induced deaminase. Robert Wuerffel,Lili Wang,Fernando Grigera,John Manis,Erik Selsinget al. Immunity, 2007, 27 (5), pp.711-22. ⟨10.1016/j.immuni.2007.09.007⟩ Article dans une revue hal-00363968v1
Use of both CD63 up regulation and IgE down regulation for the flow cytometric analysis of allergen induced basophil activation. Definition of an activation index. Jean Sainte-Laudy,Ahmed Boumédiène,F. Touraine,Isabelle Orsel,C. Brianchonet al. Inflammation Research, 2007, 56 (7), pp.291-6. ⟨10.1007/s00011-007-7014-5⟩ Article dans une revue istex hal-00166018v1
The 3' IgH locus control region is sufficient to deregulate a c-myc transgene and promote mature B cell malignancies with a predominant Burkitt-like phenotype. Véronique Truffinet,Eric Pinaud,Nadine Cogné,Barbara Petit,Laurence Guglielmiet al. Journal of Immunology, 2007, 179 (9), pp.6033-6042 Article dans une revue hal-00181178v1
Germ line transcription in mice bearing neor gene downstream of Igamma3 exon in the Ig heavy chain locus. Maha Samara,Zéliha Oruc,Hei-Lanne Dougier,Tawer Essawi,Michel Cognéet al. International Immunology, 2006, 18 (4), pp.581-589. ⟨10.1093/intimm/dxh400⟩ Article dans une revue hal-00021571v1
Interallelic class switch recombination can reverse allelic exclusion and allow trans-complementation of an IgH locus switching defect. Hei-Lanne Dougier,Stéphane Reynaud,Eric Pinaud,Claire Carrion,Laurent Delpyet al. European Journal of Immunology, 2006, 36 (8), pp.2181-91. ⟨10.1002/eji.200535529⟩ Article dans une revue hal-00088115v1
Polyclonal IgG4 hypergammaglobulinemia associated with plasmacytic lymphadenopathy, anemia and nephropathy. Emmanuelle Boulanger,Vincent Fuentes,Véronique Meignin,Béatrice Mougenot,Sylvaine Labaumeet al. Annals of Hematology, 2006, 85 (12), pp.833-40. ⟨10.1007/s00277-006-0158-5⟩ Article dans une revue istex hal-00451895v1
Light chain inclusion permits terminal B cell differentiation and does not necessarily result in autoreactivity. Christophe Sirac,Claire Carrion,Sophie Duchez,Isabelle Comte,Michel Cogné Proceedings of the National Academy of Sciences of the United States of America, 2006, 103 (20), pp.7747-52. ⟨10.1073/pnas.0509121103⟩ Article dans une revue hal-00073857v1
Role of the monoclonal kappa chain V domain and reversibility of renal damage in a transgenic model of acquired Fanconi syndrome. Christophe Sirac,Franck Bridoux,Claire Carrion,Olivier Devuyst,Béatrice Fernandezet al. Blood, 2006, 108 (2), pp.536-543. ⟨10.1182/blood-2005-11-4419⟩ Article dans une revue hal-00085051v1
Analysis of IgE down regulation induced by basophil activation. Application to the diagnosis of muscle relaxant allergic hypersensitivity by flow cytometry. J. Sainte-Laudy,Ahmed Boumédiène,F. Touraine,I. Orsel,Michel Cogné Inflammation Research, 2006, 55 Suppl 1, pp.S21-2. ⟨10.1007/s00011-005-0023-3⟩ Article dans une revue istex hal-00452816v1
Platelet activation after aortic prosthetic valve surgery. Alexandre Leguyader,Reina Watanabe,Julien Berbé,Ahmed Boumédiène,Michel Cognéet al. Interactive Cardiovascular and Thoracic Surgery, 2006, 5 (1), pp.60-4. ⟨10.1510/icvts.2005.115733⟩ Article dans une revue hal-00452815v1
The chicken β-globin HS4 insulator is not a silver bullet to obtain copy-number dependent expression of transgenes in stable B cell transfectants Véronique Truffinet,Laurence Guglielmi,Michel Cogné,Yves Denizot Immunology Letters, 2005, 96(2), pp.303-4. ⟨10.1016/j.imlet.2004.09.002⟩ Article dans une revue istex hal-00022648v1
Interallelic Class Switch Recombination Contributes Significantly to Class Switching in Mouse B Cells Stéphane Reynaud,Laurent Delpy,Laurence Fleury,Hei-Lanne Dougier,Christophe Siracet al. Journal of Immunology, 2005, 174, pp.5905-5906 Article dans une revue hal-00022865v1
Interallelic class switch recombination contributes significantly to class switching in mouse B cells. Stéphane Reynaud,Laurent Delpy,Laurence Fleury,Hei-Lanne Dougier,Christophe Siracet al. Journal of Immunology, 2005, 174 (10), pp.6176-83 Article dans une revue hal-00458866v1
Fanconi's syndrome induced by a monoclonal Vkappa3 light chain in Waldenstrom's macroglobulinemia. Franck Bridoux,Christophe Sirac,V. Hugue,Catherine Decourt,A. Thierryet al. American Journal of Kidney Diseases, 2005, 45 (4), pp.749-57. ⟨10.1053/j.ajkd.2004.12.020⟩ Article dans une revue hal-00022808v1
The 5′HS4 insulator element is an efficient tool to analyse the transient expression of an Eμ-GFP vector in a transgenic mouse model Laurence Guglielmi,Véronique Truffinet,Claire Carrion,Marc Le Bert,Nadine Cognéet al. Transgenic Research, 2005, 14(4), pp.361-364. ⟨10.1007/s11248-005-3239-7⟩ Article dans une revue hal-00023265v1
Indolent lymphoplasmacytic and marginal zone B-cell lymphomas: absence of both IRF4 and Ki67 expression identifies a better prognosis subgroup. Barbara Petit,Mp Chaury,Arnaud Jaccard,Nathalie Gachard,S. Moalic-Judgeet al. Haematologica, 2005, 90(2), pp.200-6 Article dans une revue hal-00022403v1
Immunologic basis for the rare occurrence of true nonsecretory plasma cell dyscrasias. Catherine Decourt,Horia Radu Galea,Christophe Sirac,Michel Cogné Journal of Leukocyte Biology, 2004, 76 (3), pp.528-36. ⟨10.1189/jlb.0803382⟩ Article dans une revue hal-00023271v1
Transcription-dependent somatic hypermutation occurs at similar levels on functional and nonfunctional rearranged IgH alleles. Laurent Delpy,Christophe Sirac,Caroline Le Morvan,Michel Cogné Journal of Immunology, 2004, 173 (3), pp.1842-8 Article dans une revue hal-00023372v1
The polymorphism of the locus control region lying downstream the human IgH locus is restricted to hs1,2 but not to hs3 and hs4 enhancers. Laurence Guglielmi,Véronique Truffinet,Emmanuelle Magnoux,Michel Cogné,Yves Denizot Immunology Letters, 2004, 94 (1-2), pp.77-81. ⟨10.1016/j.imlet.2004.04.003⟩ Article dans une revue istex hal-00023366v1
Induction of somatic hypermutation by antigen-specific B cell receptors in the human BL2 cell line. Florence Glaudet,Vincent Denis,Michel Cogné,Ahmed Amine Khamlichi European Journal of Immunology, 2004, 34 (6), pp.1637-45. ⟨10.1002/eji.200324741⟩ Article dans une revue hal-00023350v1
RNA surveillance down-regulates expression of nonfunctional kappa alleles and detects premature termination within the last kappa exon. Laurent Delpy,Christophe Sirac,Emmanuelle Magnoux,Sophie Duchez,Michel Cogné Proceedings of the National Academy of Sciences of the United States of America, 2004, 101 (19), pp.7375-80. ⟨10.1073/pnas.0305586101⟩ Article dans une revue hal-00023270v1
Immunoglobulin class-switch recombination in mice devoid of any S mu tandem repeat. Ahmed Amine Khamlichi,Florence Glaudet,Zéliha Oruc,Vincent Denis,Marc Le Bertet al. Blood, 2004, 103 (10), pp.3828-36. ⟨10.1182/blood-2003-10-3470⟩ Article dans une revue hal-00023269v1
A monoclonal V kappa l light chain responsible for incomplete proximal tubulopathy. Catherine Decourt,Franck Bridoux,Guy Touchard,Michel Cogné American Journal of Kidney Diseases, 2003, 41 (2), pp.497-504. ⟨10.1053/ajkd.2003.50062⟩ Article dans une revue hal-00023380v1
Nuclear factors, hs1,2 enhancer and IgA nephropathy. Barbara Bessette,Laurence Guglielmi,Michel Cogné,Yves Denizot Kidney International, 2003, 63 (2), pp.767. ⟨10.1046/j.1523-1755.2003.00789.x⟩ Article dans une revue hal-00023525v1
Germ-line transcription occurs on both the functional and the non-functional alleles of immunoglobulin constant heavy chain genes. Laurent Delpy,Marc Le Bert,Michel Cogné,Ahmed Amine Khamlichi European Journal of Immunology, 2003, 33 (8), pp.2108-13. ⟨10.1002/eji.200323969⟩ Article dans une revue hal-00023385v1
Effect of the Eμ IgH enhancer on expression of a GFP reporter gene in transfected B cells and transgenic mice Laurence Guglielmi,Marc Le Bert,Michel Cogné,Yves Denizot Immunology Letters, 2003, 86(1), pp.77-83. ⟨10.1016/S0165-2478(02)00264-X⟩ Article dans une revue istex hal-00023530v1
The beta-globin HS4 insulator confers copy-number dependent expression of IgH regulatory elements in stable B cell transfectants. Laurence Guglielmi,Véronique Truffinet,Michel Cogné,Yves Denizot Immunology Letters, 2003, 89 (2-3), pp.119-23. ⟨10.1016/S0165-2478(03)00126-3⟩ Article dans une revue istex hal-00023379v1
Insulators to improve expression of a 3(')IgH LCR-driven reporter gene in transgenic mouse models. Laurence Guglielmi,Marc Le Bert,Véronique Truffinet,Michel Cogné,Yves Denizot Biochemical and Biophysical Research Communications, 2003, 307 (3), pp.466-71. ⟨10.1016/S0006-291X(03)01185-9⟩ Article dans une revue istex hal-00023524v1
Combination of 3' and 5' IgH regulatory elements mimics the B-specific endogenous expression pattern of IgH genes from pro-B cells to mature B cells in a transgenic mouse model. Laurence Guglielmi,Marc Le Bert,Isabelle Comte,Marie Laure Dessain,Mireille Drouetet al. Biochimica et Biophysica Acta - Molecular Cell Research, 2003, 1642 (3), pp.181-90. ⟨10.1016/j.bbamcr.2003.08.005⟩ Article dans une revue istex hal-00023378v1
The immunoglobulin heavy-chain locus hs3b and hs4 3' enhancers are dispensable for VDJ assembly and somatic hypermutation. Caroline Le Morvan,Eric Pinaud,Catherine Decourt,Armelle Cuvillier,Michel Cogné Blood, 2003, 102 (4), pp.1421-7. ⟨10.1182/blood-2002-12-3827⟩ Article dans une revue hal-00023823v1
Molecular study of an IgG1kappa cryoglobulin yielding organized microtubular deposits and glomerulonephritis in the course of chronic lymphocytic leukaemia. H.R. Galea,Franck Bridoux,Jean-Claude Aldigier,François Paraf,Dominique Bordessouleet al. Clinical and Experimental Immunology, 2002, 129 (1), pp.113-8. ⟨10.1046/j.1365-2249.2002.01896.x⟩ Article dans une revue hal-00023688v1
Analysis of three genetic markers in IgA nephropathy patients from a single region. Mireille Drouet,V. Aupetit,Yves Denizot,M. Bois,Franck Bridouxet al. Clinical Nephrology, 2002, 57 (4), pp.253-60. ⟨10.5414/cnp57253⟩ Article dans une revue hal-00023535v1
Light chain myeloma plasma cells induce a strong cell-mediated immune response mainly directed against the monoclonal light chain determinants in a murine experimental model. Horia Galea,Yves Denizot,Michel Cogné Cancer Immunology, Immunotherapy, 2002, 51 (4), pp.229-34. ⟨10.1007/s00262-002-0274-6⟩ Article dans une revue hal-00023825v1
192 and 55 paraoxonase-1 gene polymorphisms and coronary artery disease in Hemodialysis patients. Thierry Dantoine,Michel Cogné,Jean-Pierre Charmes,Louis Merle,Mireille Drouetet al. Clinical Journal of the American Society of Nephrology, 2002 Article dans une revue hal-01336537v1
GM-CSF and IL-12 production by malignant plasma cells promotes cell-mediated immune responses against monoclonal Ig determinants in a light chain myeloma model. H.R. Galea,Michel Cogné Clinical and Experimental Immunology, 2002, 129 (2), pp.247-53. ⟨10.1046/j.1365-2249.2002.01929.x⟩ Article dans une revue hal-00023536v1
Implication des facteurs vasculaires dans les troubles cognitifs du sujet âgé : relation entre le polymorphisme 192 de la paraoxonase 1 et la maladie d’Alzheimer. Thierry Dantoine,M Drouet,J. Debord,H Lacroix,Louis Merleet al. La Revue de Médecine Interne, 2002 Article dans une revue hal-01338479v1
B cell development arrest upon insertion of a neo gene between JH and Emu: promoter competition results in transcriptional silencing of germline JH and complete VDJ rearrangements. Laurent Delpy,Catherine Decourt,Marc Le Bert,Michel Cogné Journal of Immunology, 2002, 169 (12), pp.6875-82 Article dans une revue hal-00023696v1
Implication of paraoxonase-1 polymorphism 192 in Alzheimer’s disease. Thierry Dantoine,J. Debord,M. Drouet,Louis Merle,Michel Cogné Annals of the New York Academy of Sciences, 2002 Article dans une revue hal-01335856v1
Localization of the 3′ IgH Locus Elements that Effect Long-Distance Regulation of Class Switch Recombination Eric Pinaud,Ahmed Amine Khamlichi,Caroline Le Morvan,Mireille Drouet,Valérie Nalessoet al. Immunity, 2001, 15 (2), pp.187-199. ⟨10.1016/s1074-7613(01)00181-9⟩ Article dans une revue hal-03480612v1
Characterization of the murine gene for subunit VIIaL of cytochrome c oxidase. K. Chantrel-Groussard,Laurent Delpy,Marie-Hélène Ratinaud,Michel Cogné Comptes rendus de l’Académie des sciences. Série III, Sciences de la vie, 2001, 324 (12), pp.1117-23 Article dans une revue hal-00458870v1
Heavy-Chain Deposition Disease Pierre Aucouturier,Ahmed A Khamlichi,Guy Touchard,Eve Justrabo,Michel Cognéet al. New England Journal of Medicine, 1993, 329 (19), pp.1389 - 1393. ⟨10.1056/NEJM199311043291905⟩ Article dans une revue inserm-01876787v1
Complementary DNA sequence of human amyloidogenic immunoglobulin light-chain precursors. Pierre Aucouturier,Ahmed A Khamlichi,Jean-Louis Preud'Homme,Marc Bauwens,Guy Touchardet al. Biochemical Journal, 1992, 285, pp.149-52. ⟨10.1042/bj2850149⟩ Article dans une revue inserm-01876794v1
Structure of a monoclonal kappa chain of the V kappa IV subgroup in the kidney and plasma cells in light chain deposition disease. Michel Cogné,Jean-Louis Preud'Homme,Marc Bauwens,Guy Touchard,Pierre Aucouturier Journal of Clinical Investigation, 1991, 87 (6), pp.2186 - 2190. ⟨10.1172/JCI115252⟩ Article dans une revue inserm-01876801v1

Communication dans un congrès (25)

Integrative Single-Cell RNA-Seq and Single-Cell ATAC-Seq Analysis of Human Plasma Cell Differentiation Elina Alaterre,Sara Ovejero,Marion Espéli,Thierry Fest,Michel Cognéet al. 65th Annual Meeting of the American Society of Hematology (ASH 2023), American Society of Hematology (ASH), Dec 2023, San Diego, United States. ⟨10.1182/blood-2023-181507⟩ Communication dans un congrès hal-04513440v1
A Prospective Phase II Trial of Lenalidomide and Dexamethasone (Len-Dex) in POEMS Syndrome Arnaud Jaccard,A. Danielou-Lazareth,L. Karlin,S. Choquet,L. Frenzelet al. 15th International Myeloma Workshop, Sep 2015, Rome, Italy. pp.e57, ⟨10.1016/j.clml.2015.07.197⟩ Communication dans un congrès hal-01228183v1
Control of B cell fate after AID-mediated modulation of BCR expression Michel Cogné Symposium "Antibodies: the good, the bad, and the promising, Feb 2014, Amsterdam, Netherlands Communication dans un congrès hal-00949511v1
BCR expression and B Cell Fate Michel Cogné French Hematology Society 2014 congress, Mar 2014, Paris, France Communication dans un congrès hal-00949513v1
B cells switching to deadly paths Michel Cogné Henry Kunkel Society's 22nd Annual Meeting, "Human Immunology in Health and Disease, Apr 2014, New-York, United States Communication dans un congrès hal-00949516v1
Immunoglobulin genes in mature B cells: from biallelic accessibility to monoallelic expression Michel Cogné Symposium "Allelic gene regulation in health and disease", Feb 2013, Toulouse, France Communication dans un congrès hal-00949506v1
Modulation of B cell fate upon AID-mediated Ig gene recombination Michel Cogné 3rd workshop normal and neoplastic B cells, Sep 2013, Oléron, France Communication dans un congrès hal-00949547v1
Breakthrough of high troughput studies in marginal zone lymphomas and Waldenström macroglobulinemia Michel Cogné 3rd Workshop Normal and neoplastic B cells, Sep 2013, Oléron, France Communication dans un congrès hal-00949548v1
Symposium &quot;Allelic gene regulation in health and disease Michel Cogné Fédération de Médecine Translationnelle de Strasbourg" (FMTS), Dec 2013, Strasbourg, France Communication dans un congrès hal-00949510v1
Locus suicide recombination in mature B cells Michel Cogné Mutations, Malignancy and Memory, Mar 2012, Boston, United States Communication dans un congrès hal-00697686v1
Locus suicide recombination in mature B cells Michel Cogné Keystone meeting "Mutations, Malignancy and Memory, Mar 2012, Boston, United States Communication dans un congrès hal-00949503v1
In vitro and in vivo evaluation of anti-CD20 antibodies shows the IgA class to surpass IgG for direct effect on target cells. Michel Cogné Forum "Anticorps et ciblage thérapeutique" du GDR ACCITH, Sep 2011, Strasbourg, France Communication dans un congrès hal-00697682v1
Modèles murins d'étude mutationnelle du locus IgH et lymphomogenèse Michel Cogné 1st French Lymphoma Workshop, Rennes, 20-21 janvier 2011, Jan 2011, Rennes, France Communication dans un congrès hal-00949493v1
Regulation of immunoglobulin expression in mature B cells Michel Cogné International meeting on "B cells and Antibodies", Jerusalem, October 23-26, 2011, Oct 2011, Jésuralem, Israel Communication dans un congrès hal-00949500v1
Modèles murins d'étude mutationnelle du locus IgH et lymphomogenèse Michel Cogné 1st French Lymphoma Workshop, Jan 2011, Rennes, France Communication dans un congrès hal-00697680v1
In vitro and in vivo evaluation of anti-CD20 antibodies shows the IgA class to surpass IgG for direct effect on target cells. Michel Cogné ACCITH Meeting "Antibodies and therapeutic targeting, Sep 2011, Strasbourg, France Communication dans un congrès hal-00949494v1
Regulation of immunoglobulin expression in mature B cells Michel Cogné International meeting on "B cells and Antibodies, Oct 2011, Jérusalem, Israel Communication dans un congrès hal-00697685v1
Production of IgA antibodies and their variants. Michel Cogné 9th International Congress on Recombinant Antibodies 2010, Jun 2010, Berlin, Germany Communication dans un congrès hal-00697674v1
Régulation et dérégulation: les moteurs génétiques exposant le lymphocyte B à la perte de contrôle Michel Cogné 21èmes journées de l'Association Nationale des Enseignants de Biologie Cellulaire, Sep 2010, Aubazine, France Communication dans un congrès hal-00697678v1
Régulation de l'expression du locus IGH et oncogenèse Michel Cogné Congrès 2010 du Club Hématopoièse et oncogenèse (CHO), Sep 2010, Giens, France Communication dans un congrès hal-00697676v1
Applying Cutting-Edge Antibody Engineering For the Development of New Generation of Humanised Antibodies Michel Cogné IQPC meeting on Therapeutic antibodies, Sep 2009, London, United Kingdom Communication dans un congrès hal-00697672v1
Autologus stern celle transplantation (ASCT) versus oral melphalan and high-dose dexamethasone in patients with AL (primary) amyloisdosis : results of the French multicentric randomized trial (MAG and IFM intergroup). Arnaud Jaccard,P. Moreau,V. Leblond,X. Leleu,L Bennoubkeret al. Communication orale présentée à 'The American Society of Hematology 47th Annual meeting and Exposition", Dec 2005, Nouvelle Orléans (Louisiane), United States Communication dans un congrès hal-01135622v1
Rôle du polymorphisme génétique de la paraoxonase 1 dans la maladie d’Alzheimer. Thierry Dantoine,Mireille Drouet,J. Debord,Michel Cogné,Louis Merleet al. VIIème Congrès International Francophone de Gérontologie. Bruxelles, Belgique, 2002, Bruxelles, France Communication dans un congrès hal-01336564v1
Démence du sujet âgé et polymorphisme génétique de la paraoxonase 1. Thierry Dantoine,C Puech,Mireille Drouet,J. Debord,Laurence Bernard-Bourzeixet al. Société Française de Gériatrie et de Gérontologie, 2002, Limoges, France Communication dans un congrès hal-01338464v1
Polymorphisme génétique de la paraoxonase 1 et risque coronarien de l'insuffisant rénal chronique hémodialysé. C Rebeyrotte,J. Debord,Mireille Drouet,Thierry Dantoine,Jean-Pierre Charmeset al. Société de Néphrologie, 2000, Tours, France Communication dans un congrès hal-01337138v1

Poster de conférence (3)

Exploiting transcription-replication conflicts as a novel therapeutic intervention in multiple myeloma Laure Dutrieux,Antoine Guillemin,Yea-Lih Lin,Malik Lutzmann,Guilhem Requirandet al. 20th International Myeloma Society Annual Meeting (IMS 2023), Sep 2023, Athène, Greece. , Clinical Lymphoma, Myeloma and Leukemia, 23 (Suppl. 2), pp.S139 / P188, 2023, The Abstract from International Myeloma Society 20th Annual Meeting and Exposition Poster de conférence hal-05485282v1
Exploiting transcription-replication conflicts as a novel therapeutic intervention in multiple myeloma Laure Dutrieux,Yea-Lih Lin,Malik Lutzmann,Guilhem Requirand,Nicolas Robertet al. 63rd American Society of Hematology Annual Meeting and Exposition (ASH 2021), Dec 2021, Atlanta (GA), United States. , Blood, 138 (Suppl. 1), pp.1582, 2021, Annual Meeting Abstracts. ⟨10.1182/blood-2021-151530⟩ Poster de conférence hal-05520336v1
Granzyme B-secreting B cells as a potential cell therapeutic Mélanie Chesneau,Richard Danger,Sabine Le Bot,Cyrielle Poulaouec,Matthieu Fillouxet al. FOCIS 2019, Jun 2019, Boston, United States Poster de conférence inserm-02161909v1

Chapitre d'ouvrage (2)

Atteintes uro-néphrologiques au cours des amyloses Franck Bridoux,Arnaud Jaccard,Christophe Sirac,J. Gillmore,Michel Cognéet al. Atteintes uro-néphrologiques au cours des maladies systémiques, Flammarion Médecine Sciences, pp.1-22, 2009 Chapitre d'ouvrage hal-00453323v1
Renal disease in cryoglobulinemic vasculitis Franck Bridoux,Christophe Sirac,Arnaud Jaccard,R. Abou Ayache,Jm Goujonet al. The kidney in systemic autoimmune diseases, Elsevier, pp.215-240, 2008 Chapitre d'ouvrage hal-00453329v1

Brevet (2)

Mammifère non-humain transgénique pour la région constante de la chaîne lourde des immunoglobulines humaines de classe G et ses applications Michel Cogné,Nadine Cogné,Sophie Duchez,Eric Pinaud Union européenne, N° de brevet: WO2009106773. 2009 Brevet hal-00514482v1
Mammifère non-humain transgénique pour la région constante de la chaîne lourde des IgA humaines et ses applications (monoclonaux humanisés à destinée muqueuse) Michel Cogné,Caroline Le Morvan,Christophe Sirac N° de brevet: WO2005047333. 2005 Brevet hal-00514480v1

Pré-publication, Document de travail (2)

REL deregulation stands as a primary hit for AID-imprinted B-cells along the germinal center competition Léa Prévaud,Christelle Vincent-Fabert,Tiffany Marchiol,Quentin Lemasson,Catherine Ouket al. 2024 Pré-publication, Document de travail hal-04798834v1
Glomerulosclerosis and kidney failure in a mouse model of monoclonal immunoglobulin light-chain deposition disease Sébastien Bender,Maria Victoria Ayala,Amélie Bonaud,Vincent Javaugue,Claire Carrionet al. 2019 Pré-publication, Document de travail (preprint/prepublication) hal-03967308v1