Michel Treilhou

Présentation

Publications

Article dans une revue (39)

A New Kv1.3 Channel Blocker from the Venom of the Ant Tetramorium bicarinatum Guillaume Boy,Laurence Jouvensal,Nathan Téné,Jean-Luc Carayon,Elsa Bonnaféet al. Toxins, 2025, 17 (8), pp.379. ⟨10.3390/toxins17080379⟩ Article dans une revue hal-05233382v1
Isolation, NMR Characterization, and Bioactivity of a Flavonoid Triglycoside from Anthyllis henoniana Stems: Antioxidant and Antiproliferative Effects on MDA-MB-231 Breast Cancer Cells Amani Ayachi,Guillaume Boy,Sonda Samet,Nathan Téné,Bouthaina Bouzayaniet al. Antioxidants , 2024, 13 (7), pp.793. ⟨10.3390/antiox13070793⟩ Article dans une revue hal-04635159v1
Adaptive trade-offs between vertebrate defence and insect predation drive Amazonian ant venom evolution Axel Touchard,Samuel D Robinson,Hadrien Lalagüe,Steven Ascoët,Arnaud Billetet al. Proceedings of the Royal Society B: Biological Sciences, 2024, 291 (2035), pp.20242184. ⟨10.1098/rspb.2024.2184⟩ Article dans une revue hal-04795576v1
MRGPRB2/X2 and the Analogous Effects of Its Agonist and Antagonist in DSS-induced Colitis in Mice Karthi Duraisamy,Mukesh Kumar,Abdullah Nawabjan,Emily Kwun Kwan Lo,Ming Hui Linet al. Biomedicine and Pharmacotherapy, 2024, 174, pp.116471. ⟨10.1016/j.biopha.2024.116471⟩ Article dans une revue hal-05155768v1
The mechanism underlying toxicity of a venom peptide against insects reveals how ants are master at disrupting membranes Steven Ascoët,Axel Touchard,Nathan Téné,Benjamin Lefranc,Jérôme Leprinceet al. iScience, 2023, 26 (3), pp.106157. ⟨10.1016/j.isci.2023.106157⟩ Article dans une revue hal-04071274v1
Effect of the Harvest Season of Anthyllis henoniana Stems on Antioxidant and Antimicrobial Activities: Phytochemical Profiling of Their Ethyl Acetate Extracts Amani Ayachi,Amer Ben Younes,Ameni Ben Ammar,Bouthaina Bouzayani,Sonda Sametet al. Molecules, 2023, 28, ⟨10.3390/molecules28093947⟩ Article dans une revue hal-04866851v1
Ant venoms contain vertebrate-selective pain-causing sodium channel toxins Samuel D Robinson,Jennifer R Deuis,Axel Touchard,Angelo Keramidas,Alexander Muelleret al. Nature Communications, 2023, 14 (1), pp.2977. ⟨10.1038/s41467-023-38839-1⟩ Article dans une revue hal-04750225v1
The mechanism underlying toxicity of a venom peptide against insects reveals how ants are master at disrupting membranes Steven Ascoët,Axel Touchard,Nathan Téné,Benjamin Lefranc,Jérôme Leprinceet al. iScience, 2023, 26 (3), pp.106157. ⟨10.1016/j.isci.2023.106157⟩ Article dans une revue hal-05484980v1
Discovery of an Insect Neuroactive Helix Ring Peptide from Ant Venom Valentine Barassé,Laurence Jouvensal,Guillaume Boy,Arnaud Billet,Steven Ascoëtet al. Toxins, 2023, 15 (10), pp.600. ⟨10.3390/toxins15100600⟩ Article dans une revue hal-04390519v1
HESI-MS/MS Analysis of Phenolic Compounds from Calendula aegyptiaca Fruits Extracts and Evaluation of Their Antioxidant Activities Wafa Grati,Sonda Samet,Bouthaina Bouzayani,Amani Ayachi,Michel Treilhouet al. Molecules, 2022, 27, ⟨10.3390/molecules27072314⟩ Article dans une revue hal-04823160v1
Antioxidant and Antimicrobial Activities of Erodium arborescens Aerial Part Extracts and Characterization by LC-HESI-MS2 of Its Acetone Extract Sonda Samet,Amani Ayachi,Mariam Fourati,Lotfi Mallouli,Noureddine Alloucheet al. Molecules, 2022, 27, ⟨10.3390/molecules27144399⟩ Article dans une revue hal-04816419v1
Differential immunomodulatory effects of six pesticides of different chemical classes on human monocyte-derived macrophage functions Melissa Parny,Agnès Coste,Agnes Aubouy,Mouna Rahabi,Melissa Pratet al. Food and Chemical Toxicology, 2022, 163 (9), pp.112992. ⟨10.1016/j.fct.2022.112992⟩ Article dans une revue hal-04008003v1
Venomics survey of six myrmicine ants provides insights into the molecular and structural diversity of their peptide toxins Valentine Barassé,Nathan Téné,Christophe Klopp,Françoise Paquet,Niklas Tysklindet al. Insect Biochemistry and Molecular Biology, 2022, 151, pp. 103876. ⟨10.1016/j.ibmb.2022.103876⟩ Article dans une revue hal-04446316v1
P17 induces chemotaxis and differentiation of monocytes via MRGPRX2-mediated mast cell–line activation Karthi Duraisamy,Kailash Singh,Mukesh Kumar,Benjamin Lefranc,Elsa Bonnaféet al. Journal of Allergy and Clinical Immunology, 2022, 149 (1), pp.275-291. ⟨10.1016/j.jaci.2021.04.040⟩ Article dans une revue hal-04144398v1
A carvacrol‐based product reduces Campylobacter jejuni load and alters microbiota composition in the caeca of chickens Marion Allaoua,Elsa Bonnafé,Pierre Etienne,Virginie Noirot,Jean‐françois Gabarrouet al. Journal of Applied Microbiology, 2022, 132 (6), pp.4501-4516. ⟨10.1111/jam.15521⟩ Article dans une revue hal-03607325v1
ESI-MS/MS Analysis of Phenolic Compounds from Aeonium arboreum Leaf Extracts and Evaluation of their Antioxidant and Antimicrobial Activities Sahar Affes,Amer Ben Younes,Donyez Frikha,Noureddine Allouche,Michel Treilhouet al. Molecules, 2021, 26, ⟨10.3390/molecules26144338⟩ Article dans une revue hal-04823173v1
Comparative study of the effects of ziram and disulfiram on human monocyte-derived macrophage functions and polarization: involvement of zinc Melissa Parny,José Bernad,Mélissa Prat,Marie Salon,Agnès Aubouyet al. Cell Biology and Toxicology, 2020, 37 (3), pp.379-400. ⟨10.1007/s10565-020-09540-6⟩ Article dans une revue hal-03551386v1
Venom peptide repertoire of the european myrmicine ant manica rubida: identification of insecticidal toxins Axel Touchard,Samira R Aili,Nathan Téné,Valentine Barassé,Christophe Kloppet al. Journal of Proteome Research, 2020, 19 (4), pp.1800-1811. ⟨10.1021/acs.jproteome.0c00048⟩ Article dans une revue (article de synthèse) hal-02570243v1
The Peptide Venom Composition of the Fierce Stinging Ant Tetraponera aethiops (Formicidae: Pseudomyrmecinae) Valentine Barassé,Axel Touchard,Nathan Téné,Maurice Tindo,Martin Kenneet al. Toxins, 2019, 11 (12), pp.732. ⟨10.3390/toxins11120732⟩ Article dans une revue hal-03115116v1
Deciphering the Molecular Diversity of an Ant Venom Peptidome through a Venomics Approach Axel Touchard,Nathan Téné,Philippe Chan Tchi Song,Benjamin Lefranc,Jérôme Leprinceet al. Journal of Proteome Research, 2018, 17 (10), pp.3503 - 3516. ⟨10.1021/acs.jproteome.8b00452⟩ Article dans une revue hal-01939298v1
Pharmacokinetic and antimicrobial activity of a new carvacrol-based product against a human pathogen, Campylobacter jejuni M. Allaoua,P. Etienne,V. Noirot,Jean-Luc Carayon,Joseph-Nathan Téné Ghomsiet al. Journal of Applied Microbiology, 2018, 125 (4), pp.1162-1174. ⟨10.1111/jam.13915⟩ Article dans une revue hal-02414870v1
Anti-Helicobacter pylori Properties of the Ant-Venom Peptide Bicarinalin Jesus Guzman,Joseph-Nathan Téné Ghomsi,Axel Touchard,Denis Castillo,Haouaria Belkhelfaet al. Toxins, 2017, 10 (1), pp.21. ⟨10.3390/toxins10010021⟩ Article dans une revue hal-02415873v1
Le P17, un nouveau peptide antimicrobien, favorise l’activité antifongique des macrophages via l’induction des récepteurs Mannose et Dectine-1 et contribue à la résolution d’une candidose digestive expérimentale Khaddouj Benmoussa,Hélène Authier,Mélissa Prat,Mohammad Alaeddine,Lise Lefèvreet al. Journal of Medical Mycology = Journal de Mycologie Médicale, 2017, 27 (3), pp.e11-e12. ⟨10.1016/j.mycmed.2017.04.033⟩ Article dans une revue hal-02417770v1
P17, an Original Host Defense Peptide from Ant Venom, Promotes Antifungal Activities of Macrophages through the Induction of C-Type Lectin Receptors Dependent on LTB4-Mediated PPARγ Activation Khaddouj Benmoussa,Hélène Authier,Mélissa Prat,Mohammad Alaeddine,Lise Lefèvreet al. Frontiers in Immunology, 2017, 8, pp.1650. ⟨10.3389/fimmu.2017.01650⟩ Article dans une revue hal-01960700v1
New 3-substituted-2,1-benzisoxazoles: Synthesis and antimicrobial activities Aida Chaker,Ennaji Najahi,Olivier Chatriant,Alexis Valentin,Nathan Ténéet al. Arabian Journal of Chemistry, 2017, 10 (Supplement 2), pp.S2464-S2470. ⟨10.1016/j.arabjc.2013.09.011⟩ Article dans une revue hal-02417861v1
Monoterpenoid-based preparations in beehives affect learning, memory, and gene expression in the bee brain Elsa Bonnafé,Julie Alayrangues,Lucie Hotier,Isabelle Massou,Allan Renomet al. Environmental Toxicology and Chemistry, 2017, 36 (2), pp.337-345. ⟨10.1002/etc.3527⟩ Article dans une revue hal-02434448v1
Biochemical and biophysical combined study of bicarinalin, an ant venom antimicrobial peptide Nathan Téné,Elsa Bonnafé,Fanny Berger,Aline Rifflet,Laure Guilhaudiset al. Peptides, 2016, 79, pp.103-113. ⟨10.1016/j.peptides.2016.04.001⟩ Article dans une revue istex hal-01974252v1
A peptide isolated from an ant active against Helicobacter pylori Jesus L Guzmán,Michel Treilhou,Denis Castillo,Haouaria Belkhelfa,Laila Haddioui-Hbabiet al. Planta Medica, 2016, 82 (S 01), pp.S1-S381. ⟨10.1055/s-0036-1596765⟩ Article dans une revue hal-02417889v1
Crop protection, environment, health, and biodiversity: observations and outlook Michel Treilhou,Jean-François Chollet,Michel Couderchet Environmental Science and Pollution Research, 2015, 22 (11), pp.7987-7990. ⟨10.1007/s11356-015-4528-1⟩ Article dans une revue hal-04139350v1
Effect of a thymol application on olfactory memory and gene expression levels in the brain of the honeybee Apis mellifera Elsa Bonnafé,Florian Drouard,Lucie Hotier,Jean-Luc Carayon,Pierre Martyet al. Environmental Science and Pollution Research, 2015, 22 (11), pp.8022-8030. ⟨10.1007/s11356-014-2616-2⟩ Article dans une revue hal-02418208v1
Thymol as an alternative to pesticides: persistence and effects of Apilife Var on the phototactic behavior of the honeybee Apis mellifera Jean-Luc Carayon,Nathan Téné,Elsa Bonnafé,Julie Alayrangues,Lucie Hotieret al. Environmental Science and Pollution Research, 2014, 21 (7), pp.4934-4939. ⟨10.1007/s11356-013-2143-6⟩ Article dans une revue hal-02418360v1
Potent bactericidal effects of bicarinalin against strains of the Enterobacter and Cronobacter genera Nathan Téné,Virginy Roche-Chatain,Aline Rifflet,Elsa Bonnafé,Benjamin Lefrancet al. Food Control, 2014, 42, pp.202 - 206. ⟨10.1016/j.foodcont.2014.02.026⟩ Article dans une revue istex hal-01939324v1
Synthesis and biological evaluation of new bis-indolone-N-oxides Ennaji Najahi,Alexis Valentin,Nathan Téné,Michel Treilhou,Françoise Nepveu Bioorganic Chemistry, 2013, 48, pp.16-21. ⟨10.1016/j.bioorg.2013.03.001⟩ Article dans une revue istex hal-03520953v1
Identification and characterization of a novel antimicrobial peptide from the venom of the ant Tetramorium bicarinatum. Aline Rifflet,Sabine Gavalda,Nathan Téné,Jérôme Orivel,Jérôme Leprinceet al. Peptides, 2012, 38 (2), pp.363-370. ⟨10.1016/j.peptides.2012.08.018⟩ Article dans une revue istex hal-00996401v1
Exposure to thymol decreased phototactic behaviour in the honeybee (Apis mellifera) in laboratory conditions Maelys Bergougnoux,Michel Treilhou,Catherine Armengaud Apidologie, 2012, 44 (1), pp.82-89. ⟨10.1007/s13592-012-0158-5⟩ Article dans une revue hal-01201274v1
PCBs uptake by carrots after sludge composts application: worst-case and operational practice in greenhouse conditions Caroline C. Sablayrolles,Claire Vialle,Jérôme Silvestre,Michel Treilhou,Claire Lhoutellieret al. Fresenius Environmental Bulletin, 2011, 20 (8A), pp.2141-2149 Article dans une revue hal-02645760v1
Paralyzing Action from a Distance in an Arboreal African Ant Species Aline Rifflet,Nathan Téné,Jérôme Orivel,Michel Treilhou,Alain Dejeanet al. PLoS ONE, 2011, 6 (12), pp.e28571. ⟨10.1371/journal.pone.0028571⟩ Article dans une revue hal-02053762v1
Trace determination of linear alkylbenzene sulfonates : application in artificially polluted soil-carrots system Caroline C. Sablayrolles,Mireille Montréjaud-Vignoles,Jérôme Silvestre,Michel Treilhou International Journal of Environmental Analytical Chemistry, 2009, 2009 (404836), pp.1-6. ⟨10.1155/2009/404836⟩ Article dans une revue hal-02657477v1
Development and validation of methods for the trace determination of phtalates in sludge and vegetables Caroline C. Sablayrolles,Mireille Montréjaud-Vignoles,David Benanou,Lucie Patria,Michel Treilhou Journal of Chromatography A, 2005, 1072, pp.233-242. ⟨10.1016/j.chroma.2005.02.074⟩ Article dans une revue hal-02681246v1

Poster de conférence (12)

Venin de la fourmi Tetramorium bicarinatum : découverte d'un peptide original neuroactif chez les insectes Axel Touchard,Valentine Barassé,Laurence Jouvensal,Guillaume Boy,Arnaud Billetet al. 52ème Congrès du Groupe Français de Recherches sur les Pesticides, May 2024, Lyon, France. 2024 Poster de conférence hal-05169446v1
Targeting MRGPRX2 with Venom Peptide P17: A Therapeutic Avenue for DSS-induced Colitis Karthi Duraisamy,M. Kumar,Abdullah Nawabjan,E. Lo,Ming Hui Linet al. 37th European Peptide Symposium, Aug 2024, Florence, Italy. 2024 Poster de conférence hal-05169443v1
Diversity of host defense peptides in the venom of the ant T. bicarinatum Laurence Jouvensal,Karine Loth,Axel Touchard,Arnaud Billet,Michel Treilhouet al. MuFoPAM 2023, Oct 2023, Lille, France Poster de conférence hal-04406429v1
Analogous Effects of MRGPRB2 Agonists and Antagonists in DSS-induced Colitis Mice Model Karthi Duraisamy,Mukesh Kumar,Abdullah Nawabjan,Emily Kwun Kwan Lo,Ming Hui Linet al. 23ème Congrès Du Groupe Français Des Peptides et Des Protéines, Sep 2023, Fournols, France. 2023 Poster de conférence hal-05168059v1
Investigation of the U9-MYRTX-Tb1a Mechanism, a Cytotoxic Peptide from the Ant Tetramorium Bicarinatum Venom Steven Ascoët,Nathan Téné,Axel Touchard,Benjamin Lefranc,Françoise Paquetet al. 22ème Congrès Du Groupe Français Des Peptides et Des Protéines et BPGMS5, French-Belgian Joint Meeting, May 2022, Port-Leucate, France Poster de conférence hal-05167772v1
Between Apoptosis and Necrosis: Study of U9-MYRTX-Tb1a Mechanism, a Cytotoxic Venom Peptide from the Tetramorium Bicarinatum Ant Steven Ascoët,Nathan Téné,Axel Touchard,Benjamin Lefranc,Jérôme Leprinceet al. Venoms and Toxins, Aug 2022, Oxford, United Kingdom. 2022 Poster de conférence hal-05166727v1
Comparative investigation of the mechanisms of two cytotoxic venom peptides from the ant Tetramorium bicarinatum. Steven Ascoët,Nathan Téné,Axel Touchard,Jérôme Leprince,Françoise Paquetet al. e-RT27 – 27th Meeting of the French Society of Toxinology, Dec 2021, virtual, France Poster de conférence hal-03519944v1
Analogous Venom Peptides Acting on Different Pathways: A Study of Bicarinalin and U9-MYRTX-Tb1a from T. Bicarinatum Venom Steven Ascoët,Nathan Téné,Axel Touchard,Valentine Barassé,Jérôme Leprinceet al. 1st International Electronic Conference on Toxins, Jan 2021, On line, Switzerland. 2021 Poster de conférence hal-05166047v1
Analogous peptides acting on different pathways: a comparative study of Bicarinalin and U9-MYRTX-Tb1a from an ant venom Steven Ascoët,Nathan Téné,Axel Touchard,Valentine Barassé,Jérôme Leprinceet al. 1st International Electronic Conference on Toxins, Jan 2021, Basel (online), Switzerland. , 2021 Poster de conférence hal-03191770v1
Identification and Functional Characterization of Venom Peptide P17 and Its Receptor in Host Defense Immunity Karthi Duraisamy,Kailash Singh,Mukesh Kumar,Benjamin Lefranc,Elsa Bonnaféet al. Worl Immune Regulation Meeting XIV, Mar 2020, Davos, Switzerland. 2020 Poster de conférence hal-05165838v1
Exploring the molecular diversity of ant venoms reveals conserved toxin precursors and distinctive mature peptides features among phylogenetic subfamilies Valentine Barassé,Axel Touchard,Nathan Téné,Michel Treilhou,Elsa Bonnafé GFPP21, 2019, Amboise, France. 2019 Poster de conférence hal-03186813v1
Polychlorinated biphenyl uptake by carrots after sludge composts application: waste case and operational practice in greenhouse conditions Caroline C. Sablayrolles,Claire Vialle,Jérôme Silvestre,Michel Treilhou,C. Lhoutellieret al. ISEAC 36 - 36. International Symposium on Environmental Analytical Chemistry, Sep 2010, Rome, Italy. 2010, ISEAC 36 - 36. International symposium on environmental analytical chemistry Poster de conférence hal-02754334v1

Brevet (1)

Ant Venom Peptidome Michel Treilhou,Elsa Bonnafe,Axel Touchard,Jérôme Leprince France, Patent n° : EP3594226 (A1). 2020 Brevet hal-05156825v1