Mireille Moutiez

Documents

Publications

	Flexizyme-aminoacylated shortened tRNAs demonstrate that only the aminoacylated acceptor arms of the two tRNA substrates are required for cyclodipeptide synthase activity Nicolas Canu , Carine Tellier , Morgan Babin , Robert Thai , Inès Ajel Nucleic Acids Research, 2020, 48 (20), ⟨10.1093/nar/gkaa903⟩ Journal articles hal-02978046v1
	Cyclodipeptide synthases: a promising biotechnological tool for the synthesis of diverse 2,5-diketopiperazines Nicolas Canu , Mireille Moutiez , Pascal Belin , Muriel Gondry Natural Product Reports, 2020, ⟨10.1039/c9np00036d⟩ Journal articles hal-02415937v1
	In vivo characterization of the activities of novel cyclodipeptide oxidases: new tools for increasing chemical diversity of bioproduced 2,5-diketopiperazines in Escherichia coli Fabien Le Chevalier , Isabelle Correia , Lucrèce Matheron , Morgan Babin , Mireille Moutiez Microbial Cell Factories, 2020, 19 (1), pp.178. ⟨10.1186/s12934-020-01432-y⟩ Journal articles hal-02944247v1
	Author Correction: Reprogramming Escherichia coli for the production of prenylated indole diketopiperazine alkaloids Pavlina Dubois , Isabelle Correia , Fabien Le Chevalier , Steven Dubois , Isabelle Jacques Scientific Reports, 2019, 9 (1), pp.15009. ⟨10.1038/s41598-019-51404-5⟩ Journal articles hal-02321505v1
	Reprogramming Escherichia coli for the production of prenylated indole diketopiperazine alkaloids Pavlina Dubois , Isabelle Correia , Fabien Le Chevalier , Steven Dubois , Isabelle Jacques Scientific Reports, 2019, 9 (1), pp.9208. ⟨10.1038/s41598-019-45519-y⟩ Journal articles hal-03982770v1
	Study of bicyclomycin biosynthesis in Streptomyces cinnamoneus by genetic and biochemical approaches Jerzy Witwinowski , Mireille Moutiez , Matthieu Coupet , Isabelle Correia , Pascal Belin Scientific Reports, 2019, 9 (1), pp.20226. ⟨10.1038/s41598-019-56747-7⟩ Journal articles hal-02431235v1
	A Comprehensive Overview of the Cyclodipeptide Synthase Family Enriched with the Characterization of 32 New Enzymes Muriel Gondry , Isabelle Jacques , Robert Thai , Morgan Babin , Nicolas Canu Frontiers in Microbiology, 2018, 9, pp.46. ⟨10.3389/fmicb.2018.00046⟩ Journal articles cea-01988448v1
	Structural basis for partition of the cyclodipeptide synthases into two subfamilies Gabrielle Bourgeois , Jérôme Seguin , Morgan Babin , Pascal Belin , Mireille Moutiez Journal of Structural Biology, 2018, 203 (1), pp.17-26. ⟨10.1016/j.jsb.2018.03.001⟩ Journal articles hal-01969469v1
	Incorporation of non-canonical amino acids into 2,5-diketopiperazines by cyclodipeptide synthases Nicolas Canu , Pascal Belin , Robert Thai , Isabelle Correia , Olivier Lequin Angewandte Chemie International Edition, 2018, 57 (12), pp.3118-3122. ⟨10.1002/anie.201712536⟩ Journal articles cea-01988447v1
	Aminoacyl-tRNA-Utilizing Enzymes in Natural Product Biosynthesis Mireille Moutiez , Pascal Belin , Muriel Gondry Chemical Reviews, 2017, ⟨10.1021/acs.chemrev.6b00523⟩ Journal articles hal-02390033v1
	Analysis of 51 cyclodipeptide synthases reveals the basis for substrate specificity. Isabelle B Jacques , Mireille Moutiez , Jerzy Witwinowski , Emmanuelle Darbon , Cécile Martel Nature Chemical Biology, 2015, 11 (9), pp.721-7. ⟨10.1038/nchembio.1868⟩ Journal articles hal-01430815v1
	Unravelling the mechanism of non-ribosomal peptide synthesis by cyclodipeptide synthases. Mireille Moutiez , Emmanuelle Schmitt , Jérôme Seguin , Robert Thai , Emmanuel Favry Nature Communications, 2014, 5 (October), pp.5141. ⟨10.1038/ncomms6141⟩ Journal articles hal-01098814v1
	Specificity determinants for the two tRNA substrates of the cyclodipeptide synthase AlbC from Streptomyces noursei Mireille Moutiez , Jérôme Seguin , Matthieu Fonvielle , Pascal Belin , Isabelle Béatrice Jacques Nucleic Acids Research, 2014, 42 (11), pp.7247-7258. ⟨10.1093/nar/gku348⟩ Journal articles hal-01332732v1
	High throughput screening identifies disulfide isomerase DsbC as a very efficient partner for recombinant expression of small disulfide-rich proteins in E. coli Hervé Nozach , Carole Fruchart-Gaillard , François Fenaille , Fabrice Beau , Oscar Pereira Ramos Microbial Cell Factories, 2013, 12, ⟨10.1186/1475-2859-12-37⟩ Journal articles cea-02100032v1
	Structure of the MutL$\alpha$ C-terminal domain reveals how Mlh1 contributes to Pms1 endonuclease site. Emeric Gueneau , Claudine Dherin , Pierre Legrand , Carine Tellier-Lebegue , Bernard Gilquin Nature Structural and Molecular Biology, 2013, 20 (4), pp.461-468. ⟨10.1038/nsmb.2511⟩ Journal articles hal-00817454v1
	The nonribosomal synthesis of diketopiperazines in tRNA-dependent cyclodipeptide synthase pathways Pascal Belin , Mireille Moutiez , Sylvie Lautru , Jérôme Seguin , Jean-Luc Pernodet Natural Product Reports, 2012, 29 (9), pp.961-979. ⟨10.1039/C2NP20010D⟩ Journal articles hal-03631648v1
	Nonribosomal Peptide synthesis in animals: the cyclodipeptide synthase of nematostella. Jérôme Seguin , Mireille Moutiez , Yan Li , Pascal Belin , Alain Lecoq Chem Biol, 2011, 18 (11), pp.1362-8. ⟨10.1016/j.chembiol.2011.09.010⟩ Journal articles hal-00646132v1
	Cyclodipeptide synthases, a family of class-I aminoacyl-tRNA synthetase-like enzymes involved in non-ribosomal peptide synthesis Ludovic Sauguet , Mireille Moutiez , Yan Li , Pascal Belin , Jérôme Seguin Nucleic Acids Research, 2011, 39 (10), pp.4475-4489. ⟨10.1093/nar/gkr027⟩ Journal articles cea-02000061v1
	Solution structure of the region 51-160 of human KIN17 reveals an atypical winged helix domain Ludovic Carlier , Joël Couprie , Albane Le Maire , Laure Guilhaudis , Isabelle Milazzo-Segalas Protein Science, 2009, 16 (12), pp.2750 - 2755 Journal articles hal-00425483v1
	Dynamic Combinatorial Self‐Assembly of Cyclophilin hCyp‐18 Ligands through Oxorhenium Coordination Cécile Clavaud , Julien Le Gal , Robert Thai , Mireille Moutiez , Christophe Dugave ChemBioChem, 2008, 9 (11), pp.1823-1829 Journal articles cea-01997014v1
	Biochemical properties and cellular localization of Plasmodium falciparum protein disulfide isomerase Elisabeth Mouray , Mireille Moutiez , S Girault , Christian Sergheraert , I Florent Biochimie, 2007, 89 (3), pp.337-346. ⟨10.1016/j.biochi.2006.11.001⟩ Journal articles mnhn-02070098v1
	A Tandem of SH3-like domains participates in RNA binding in KIN17, a human protein activated in response to genotoxics Albane Le Maire , Marc Schiltz , Enrico Stura , Ghislaine Pinon-Lataillade , Joël Couprie Journal of Molecular Biology, 2006, 364 (4), pp.764-776. ⟨10.1016/j.jmb.2006.09.033⟩ Journal articles hal-03633943v1
	Dual expression system suitable for high-throughput fluorescence-based screening and production of soluble proteins Sandrine Braud , Mireille Moutiez , Pascal Belin , Nicolas Abello , Pascal Drevet Journal of Proteome Research, 2005, 4 (6), pp.2137-2147. ⟨10.1021/pr050230i⟩ Journal articles hal-03633947v1
	Metal-binding stoichiometry and selectivity of the copper chaperone CopZ from Enterococcus hirae Agathe Urvoas , Mireille Moutiez , Clément Estienne , Joël Couprie , Elisabeth Mintz European Journal of Biochemistry, 2004, 271 (5), pp.993-1003. ⟨10.1111/j.1432-1033.2004.04001.x⟩ Journal articles hal-03635902v1
	Analysis of the metal-binding selectivity of the metallochaperone CopZ from Enterococcus hirae by electrospray ionization mass spectrometry Agathe Urvoas , Badia Amekraz , Christophe Moulin , Loïc Le Clainche , Reto Stöcklin Rapid Communications in Mass Spectrometry, 2003, 17 (16), pp.1889-1896. ⟨10.1002/rcm.1130⟩ Journal articles hal-03635904v1
	Synthesis and Evaluation of Glyψ(PO 2 R-N)Pro-Containing Pseudopeptides as Novel Inhibitors of the Human Cyclophilin hCyp-18 Luc Demange , Mireille Moutiez , Christophe Dugave Journal of Medicinal Chemistry, 2002, 45 (18), pp.3928-3933. ⟨10.1021/jm020865i⟩ Journal articles hal-03635906v1
	Description of the topographical changes associated to the different stages of the DsbA catalytic cycle Floriana Vinci , Joël Couprie , Piero Pucci , Eric Quéméneur , Mireille Moutiez Protein Science, 2002, 11 (7), pp.1600-1612. ⟨10.1110/ps.4960102⟩ Journal articles hal-03635908v1
	Slow Folding of Three-Fingered Toxins Is Associated with the Accumulation of Native Disulfide-Bonded Intermediates Margherita Ruoppolo , Fabio Talamo , Piero Pucci , Mireille Moutiez , Eric Quèmèneur Biochemistry, 2001, 40 (50), pp.15257-15266. ⟨10.1021/bi0111956⟩ Journal articles hal-03635910v1
	Interaction of human cyclophilin hCyp-18 with short peptides suggests the existence of two functionally independent subsites Luc Demange , Mireille Moutiez , Karine Vaudry , Christophe Dugave FEBS Letters, 2001, 505 (1), pp.191-195. ⟨10.1016/s0014-5793(01)02814-9⟩ Journal articles hal-03635916v1
	Investigation of the DsbA Mechanism through the Synthesis and Analysis of an Irreversible Enzyme−Ligand Complex Joël Couprie , Floriana Vinci , Christophe Dugave , Eric Quéméneur , Mireille Moutiez Biochemistry, 2000, 39 (22), pp.6732-6742. ⟨10.1021/bi992873f⟩ Journal articles hal-03635917v1
	Design of a gag pentapeptide analogue that binds human cyclophilin A more efficiently than the entire capsid protein: new insights for the development of novel Anti-HIV-1 drugs Quan Li , Mireille Moutiez , Jean-Baptiste Charbonnier , Karine Vaudry , André Ménez Journal of Medicinal Chemistry, 2000, 43 (9), pp.1770-1779. ⟨10.1021/jm9903139⟩ Journal articles hal-03637514v1
	On the role of the cis-proline residue in the active site of DsbA Jean-Baptiste Charbonnier , Pascal Belin , Mireille Moutiez , Enrico Stura , Eric Quéméneur Protein Science, 1999, 8 (1), pp.96-105. ⟨10.1110/ps.8.1.96⟩ Journal articles hal-03637530v1
	On the non-respect of the thermodynamic cycle of DsbA variants M. Moutiez , T.V. Burova , Thomas Haertlé , E. Quémeneur Protein Science, 1999, 8, pp.106-112 Journal articles hal-02686878v1
	Engineering cyclophilin into a proline-specific endopeptidase Eric Quéméneur , Mireille Moutiez , Jean-Baptiste Charbonnier , Andr Ménez Nature, 1998, 391 (6664), pp.301-304. ⟨10.1038/34687⟩ Journal articles hal-03637574v1
	The length of a single turn controls the overall folding rate of “Three-Fingered” snake toxins Margherita Ruoppolo , Mireille Moutiez , Maria Fiorella Mazzeo , Piero Pucci , André Ménez Biochemistry, 1998, 37 (46), pp.16060-16068. ⟨10.1021/bi981492j⟩ Journal articles hal-03637538v1
	Vasopressin trisulphide: synthesis, NMR study and affinity studies with V1 and V2 subtypes receptors Mireille Moutiez , Guy Lippens , Christian Sergheraert , André Tartar Bioorganic and Medicinal Chemistry Letters, 1997, 7 (6), pp.719-724. ⟨10.1016/S0960-894X(97)00050-4⟩ Journal articles hal-03637710v1
	Glutathione-dependent activities of $Trypanosoma\ cruzi$ p52 makes it a new member of the thiol:disulphide oxidoreductase family Mireille Moutiez , Eric Quéméneur , Christian Sergheraert , Valérie Lucas , André Tartar Biochemical Journal, 1997, 322 (1), pp.43-48. ⟨10.1042/bj3220043⟩ Journal articles hal-03637701v1
	New formulae for folding catalysts make them multi-purpose enzymes Mireille Moutiez , Régine Guthapfel , Paul Gueguen , Eric Quéméneur Biotechnology and Bioengineering, 1997, 56 (6), pp.645-649. ⟨10.1002/(SICI)1097-0290(19971220)56:6<645::AID-BIT7>3.0.CO;2-N⟩ Journal articles hal-03633940v1
	2-Amino diphenylsulfides as new inhibitors of trypanothione reductase R Fernandez-Gomez , M. Moutiez , Marc Aumercier , Gilles Bethegnies , Michel Luyckx International Journal of Antimicrobial Agents, 1995, 6 (2), pp.111-118. ⟨10.1016/0924-8579(95)00029-x⟩ Journal articles hal-03637707v1
	Synthesis of non reducible inhibitors for trypanothione reductase from Trypanosoma cruzi Anne Tromelin , M. Moutiez , D. Meziane-Cherif , M. Aumercier , A. Tartar Bioorganic and Medicinal Chemistry Letters, 1993, 3 (10), pp.1971-1976. ⟨10.1016/s0960-894x(01)80997-5⟩ Journal articles hal-02716050v1

	Dynamic combinatorial assembly of peptide-rhenium coordinates: Application to the selection of hCyp-18 inhibitors from a library of 12 × 16 components C. Dugave , C. Clavaud , J. Le Gal , R. Thai , M. Moutiez Susan Del Valle; Emanuel Escher; William D. Lubell. Peptides for Youth : The Proceedings of the 20th American Peptide Symposium(2009), 611, Springer New York, pp.3-4, 2009, Advances in Experimental Medicine and Biology book series, 978-0-387-73656-3. ⟨10.1007/978-0-387-73657-0_1⟩ Book sections hal-03633939v1
	Dynamic combinatorial assembly of peptide-rhenium coordinates: coordination chemistry for generating new analogs of hCyp-18 ligands C. Clavaud , J. Le Gal , Robert Thai , Mireille Moutiez , C. Dugave Susan Del Valle; Emanuel Escher; William D. Lubell. Peptides for Youth: The Proceedings of the 20th American Peptide Symposium, 611, Springer Science + Business Media, pp.5-6, 2009, Part of the Advances in Experimental Medicine and Biology book series, 978-0-387-73656-3. ⟨10.1007/978-0-387-73657-0_2⟩ Book sections hal-03633932v1

Mireille Moutiez

Publications

Flexizyme-aminoacylated shortened tRNAs demonstrate that only the aminoacylated acceptor arms of the two tRNA substrates are required for cyclodipeptide synthase activity

Cyclodipeptide synthases: a promising biotechnological tool for the synthesis of diverse 2,5-diketopiperazines

In vivo characterization of the activities of novel cyclodipeptide oxidases: new tools for increasing chemical diversity of bioproduced 2,5-diketopiperazines in Escherichia coli

Author Correction: Reprogramming Escherichia coli for the production of prenylated indole diketopiperazine alkaloids

Reprogramming Escherichia coli for the production of prenylated indole diketopiperazine alkaloids

Study of bicyclomycin biosynthesis in Streptomyces cinnamoneus by genetic and biochemical approaches

A Comprehensive Overview of the Cyclodipeptide Synthase Family Enriched with the Characterization of 32 New Enzymes

Structural basis for partition of the cyclodipeptide synthases into two subfamilies

Incorporation of non-canonical amino acids into 2,5-diketopiperazines by cyclodipeptide synthases

Aminoacyl-tRNA-Utilizing Enzymes in Natural Product Biosynthesis

Analysis of 51 cyclodipeptide synthases reveals the basis for substrate specificity.

Unravelling the mechanism of non-ribosomal peptide synthesis by cyclodipeptide synthases.

Specificity determinants for the two tRNA substrates of the cyclodipeptide synthase AlbC from Streptomyces noursei

High throughput screening identifies disulfide isomerase DsbC as a very efficient partner for recombinant expression of small disulfide-rich proteins in E. coli

Structure of the MutL$\alpha$ C-terminal domain reveals how Mlh1 contributes to Pms1 endonuclease site.

The nonribosomal synthesis of diketopiperazines in tRNA-dependent cyclodipeptide synthase pathways

Nonribosomal Peptide synthesis in animals: the cyclodipeptide synthase of nematostella.

Cyclodipeptide synthases, a family of class-I aminoacyl-tRNA synthetase-like enzymes involved in non-ribosomal peptide synthesis

Solution structure of the region 51-160 of human KIN17 reveals an atypical winged helix domain

Dynamic Combinatorial Self‐Assembly of Cyclophilin hCyp‐18 Ligands through Oxorhenium Coordination

Biochemical properties and cellular localization of Plasmodium falciparum protein disulfide isomerase

A Tandem of SH3-like domains participates in RNA binding in KIN17, a human protein activated in response to genotoxics

Dual expression system suitable for high-throughput fluorescence-based screening and production of soluble proteins

Metal-binding stoichiometry and selectivity of the copper chaperone CopZ from Enterococcus hirae

Analysis of the metal-binding selectivity of the metallochaperone CopZ from Enterococcus hirae by electrospray ionization mass spectrometry

Synthesis and Evaluation of Glyψ(PO 2 R-N)Pro-Containing Pseudopeptides as Novel Inhibitors of the Human Cyclophilin hCyp-18

Description of the topographical changes associated to the different stages of the DsbA catalytic cycle

Slow Folding of Three-Fingered Toxins Is Associated with the Accumulation of Native Disulfide-Bonded Intermediates

Interaction of human cyclophilin hCyp-18 with short peptides suggests the existence of two functionally independent subsites

Investigation of the DsbA Mechanism through the Synthesis and Analysis of an Irreversible Enzyme−Ligand Complex

Design of a gag pentapeptide analogue that binds human cyclophilin A more efficiently than the entire capsid protein: new insights for the development of novel Anti-HIV-1 drugs

On the role of the cis-proline residue in the active site of DsbA

On the non-respect of the thermodynamic cycle of DsbA variants

Engineering cyclophilin into a proline-specific endopeptidase

The length of a single turn controls the overall folding rate of “Three-Fingered” snake toxins

Vasopressin trisulphide: synthesis, NMR study and affinity studies with V1 and V2 subtypes receptors

Glutathione-dependent activities of $Trypanosoma\ cruzi$ p52 makes it a new member of the thiol:disulphide oxidoreductase family

New formulae for folding catalysts make them multi-purpose enzymes

2-Amino diphenylsulfides as new inhibitors of trypanothione reductase

Synthesis of non reducible inhibitors for trypanothione reductase from Trypanosoma cruzi

Dynamic combinatorial assembly of peptide-rhenium coordinates: Application to the selection of hCyp-18 inhibitors from a library of 12 × 16 components

Dynamic combinatorial assembly of peptide-rhenium coordinates: coordination chemistry for generating new analogs of hCyp-18 ligands