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nathalie hinfray



An end-to-end pipeline based on open source deep learning tools for reliable analysis of complex 3D images of ovaries

Manon Lesage , Manon Thomas , Thierry Pécot , Tu-Ky Ly , Nathalie Hinfray
Development (Cambridge, England), 2023, 150 (7), pp.dev201185. ⟨10.1242/dev.201185⟩
Journal articles hal-04062159v1

Corrigendum to ‘Refinement of an OECD test guideline for evaluating the effects of endocrine disrupting chemicals on aromatase gene expression and reproduction using novel transgenic cyp19a1a-eGFP zebrafish’ [Aquat. Toxicol. 220 (2020) 105403](S0166445X19308392)(10.1016/j.aquatox.2020.105403)

N. Hinfray , Julie de Oliveira , Edith Chadili , Benjamin Piccini , Cyril Turies
Aquatic Toxicology, 2022, 247, ⟨10.1016/j.aquatox.2022.106166⟩
Journal articles hal-03841956v1
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A comparison of behavioral and reproductive parameters between wild-type, transgenic and mutant zebrafish: Could they all be considered the same “zebrafish” for reglementary assays on endocrine disruption?

Julie de Oliveira , Edith Chadili , Cyril Turies , François Brion , Xavier Cousin
Comparative Biochemistry and Physiology - Part C: Toxicology and Pharmacology, 2021, 239, pp.108879. ⟨10.1016/j.cbpc.2020.108879⟩
Journal articles hal-03183773v1

Human and Zebrafish Nuclear Progesterone Receptors Are Differently Activated by Manifold Progestins

Clémentine Garoche , Selim Aït-Aïssa , Abdelhay Boulahtouf , Nicolas Creusot , Nathalie Hinfray
Environmental Science and Technology, 2020, 54 (15), pp.9510-9518. ⟨10.1021/acs.est.0c02056⟩
Journal articles hal-02987239v1
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Refinement of an OECD test guideline for evaluating the effects of endocrine disrupting chemicals on aromatase gene expression and reproduction using novel transgenic cyp19a1a-eGFP zebrafish

Julie de Oliveira , Edith Chadili , Benjamin Piccini , Cyril Turies , Emmanuelle Maillot-Maréchal
Aquatic Toxicology, 2020, 220, pp.105403. ⟨10.1016/j.aquatox.2020.105403⟩
Journal articles ineris-03034495v1
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Améliorer les tests de criblage des perturbateurs endocriniens

Nathalie Hinfray
Les cahiers de la Recherche : Santé, Environnement, Travail, 2019, Les perturbateurs endocriniens, 13, pp.26-28
Journal articles anses-02446269v1
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Dynamic and differential expression of the gonadal aromatase during the process of sexual differentiation in a novel transgenic cyp19a1a -eGFP zebrafish line

Nathalie Hinfray , Frédéric Sohm , Morgane Caulier , Edith Chadili , Benjamin Piccini
General and Comparative Endocrinology, 2018, 261, pp.179-189. ⟨10.1016/j.ygcen.2017.06.014⟩
Journal articles hal-01548670v1
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Mixture Concentration-Response Modeling Reveals Antagonistic Effects of Estradiol and Genistein in Combination on Brain Aromatase Gene (cyp19a1b) in Zebrafish

Nathalie Hinfray , Cleo Tebby , Benjamin Piccini , Gaëlle Bourgine , Selim Ait-Aissa
International Journal of Molecular Sciences, 2018, 19 (4), pp.1047. ⟨10.3390/ijms19041047⟩
Journal articles hal-01780218v1
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Les progestatifs, les poissons et les milieux aquatiques : apports du projet ANR « proofs »

François Brion , Clémentine Garoche , Nathalie Hinfray , Selim Ait-Aissa
Rapport Scientifique INERIS, 2017, 2016-2017, pp.14-15
Journal articles ineris-01869652v1
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Inhibitory effect of cadmium on estrogen signaling in zebrafish brain and protection by zinc

Lina Chouchene , Elisabeth Pellegrini , Marie-Madeleine Gueguen , Nathalie Hinfray , François Brion
Journal of Applied Toxicology, 2016, 36 (6), pp.863-871. ⟨10.1002/jat.3285⟩
Journal articles hal-01274217v1
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Several synthetic progestins disrupt the glial cell specific-brain aromatase expression in developing zebra fish

Joel Cano-Nicolau , Clementine Garoche , Nathalie Hinfray , Elisabeth Pellegrini , Noureddine Boujrad
Toxicology and Applied Pharmacology, 2016, 305, pp.12-21. ⟨10.1016/j.taap.2016.05.019⟩
Journal articles hal-01366373v1
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Additive effects of levonorgestrel and ethinylestradiol on brain aromatase (cyp19a1b) in zebrafish specific in vitro and in vivo bioassays

N. Hinfray , C. Tebby , C. Garoche , B. Piccini , G. Bourgine
Toxicology and Applied Pharmacology, 2016, 307, pp.108-114. ⟨10.1016/j.taap.2016.07.023⟩
Journal articles hal-01367151v1
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Localization of steroidogenic enzymes and Foxl2a in the gonads of mature zebrafish [i](Danio rerio)[/i]

Morgane Caulier , François Brion , Edith Chadili , Cyril Turies , Benjamin Piccini
Comparative Biochemistry and Physiology - Part A: Molecular and Integrative Physiology, 2015, 188, pp.96-106. ⟨10.1016/j.cbpa.2015.06.016⟩
Journal articles hal-01206346v1
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Le modèle embryonnaire de poisson zèbre transgénique cyp19a1b-GFP

Cléo Tebby , François Brion , Nathalie Hinfray
Rapport Scientifique INERIS, 2014, 2013-2014, pp.32-33
Journal articles ineris-01869498v1
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Effect of in vivo chronic exposure to clotrimazole on zebrafish testis function

Damien Baudiffier , Nathalie Hinfray , Catherine Ravaud , Nicolas Creusot , Edith Chadili
Environmental Science and Pollution Research, 2013, 20 (5), pp.2747-2760. ⟨10.1007/s11356-013-1474-7⟩
Journal articles ineris-00961800v1
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Cyp17a1 and Cyp19a1 in the zebrafish testis are differentially affected by oestradiol

Nathalie Hinfray , Rafael Henrique Nobrega , Morgane Caulier , Damien Baudiffier , Emmanuelle Maillot-Marechal
Journal of Endocrinology, 2013, 216 (3), pp.375-388. ⟨10.1530/JOE-12-0509⟩
Journal articles ineris-00961811v1

17α-Ethinylestradiol and nonylphenol affect the development of forebrain GnRH neurons through an estrogen receptors-dependent pathway.

Mélanie Vosges , Olivier Kah , Nathalie Hinfray , Edith Chadili , Yann Le Page
Reproductive Toxicology, 2012, 33 (2), pp.198-204. ⟨10.1016/j.reprotox.2011.04.005⟩
Journal articles hal-00750365v1

A critical role of follicle-stimulating hormone (Fsh) in mediating the effect of clotrimazole on testicular steroidogenesis in adult zebrafish

Damien Baudiffier , Nathalie Hinfray , Mélanie Vosges , Nicolas Creusot , Edith Chadili
Toxicology, 2012, 298 (1-3), pp.30-39. ⟨10.1016/j.tox.2012.04.012⟩
Journal articles ineris-00963381v1
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Les effets du clotrimazole sur la stéroïdogenèse testiculaire chez le poisson zèbre

Damien Baudiffier , François Brion , Nathalie Hinfray , Jean-Marc Porcher
Rapport Scientifique INERIS, 2012, 2011-2012, pp.36-38
Journal articles ineris-01869419v1

Brain cytochrome P450 aromatase activity in roach (Rutilus rutilus) : Seasonal variations and impact of environmental contaminants

Perrine Geraudie , Nathalie Hinfray , Marie Gerbron , Jean-Marc Porcher , François Brion
Aquatic Toxicology, 2011, 105 (3-4), pp.378-384. ⟨10.1016/j.aquatox.2011.07.009⟩
Journal articles ineris-00963304v1
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Adverse effects in wild fish living downstream from pharmaceutical manufacture discharges

Wilfried Sanchez , William Sremski , Benjamin Piccini , Olivier Palluel , Emmanuelle Maillot-Marechal
Environment International, 2011, 37 (8), pp.1342-1348. ⟨10.1016/j.envint.2011.06.002⟩
Journal articles ineris-00961764v1
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Characterization of testicular expression of P450 17alpha-hydroxylase, 17,20-lyase in zebrafish and its perturbation by the pharmaceutical fungicide clotrimazole

Nathalie Hinfray , Damien Baudiffier , Marcello C. Leal , Jean-Marc Porcher , Selim Ait-Aissa
General and Comparative Endocrinology, 2011, 174 (3), pp.309-317. ⟨10.1016/j.ygcen.2011.09.008⟩
Journal articles ineris-00961766v1

Endocrine effects of the tapeworm Ligula Intestinalis in its teleost host, the roach (Rutilis rutilis)

Perrine Geraudie , C. Boulange-Lecomte , Marie Gerbron , Nathalie Hinfray , François Brion
Parasitology, 2010, 137 (4), pp.697-704. ⟨10.1017/s003118200999151x⟩
Journal articles ineris-00963236v1
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Endocrine disruption in wild populations of chub (Leuciscus cephalus) in contaminated French streams

Nathalie Hinfray , Olivier Palluel , Benjamin Piccini , Wilfried Sanchez , Selim Ait-Aissa
Science of the Total Environment, 2010, 408 (9), pp.2146-2154. ⟨10.1016/j.scitotenv.2010.01.003⟩
Journal articles ineris-00961748v1

Oestrogen-induced androgen insufficiency results in a reduction of proliferation and differentiation of spermatogonia in the zebrafish testis

Paul P. de Waal , Marcello C. Leal , Angel Garcia-Lopez , Sergio Liarte , Hugo de Jonge
Journal of Endocrinology, 2009, 202, pp.287-297. ⟨10.1677/JOE-09-0050⟩
Journal articles ineris-00963210v1

Effect of (xeno)-estrogens on zebrafish P450c17 (C17, 17 alpha-hydroxylase/17, 20-lyase) mRNA and protein expression in gonadal tissue

François Brion , Nathalie Hinfray , Olivier Palluel , Julien Maillard , Isabelle Anglade
Cybium : Revue Internationale d’Ichtyologie, 2008, 32 (2, suppl. S), pp.245-246
Journal articles ineris-00963150v1
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Écotoxicologie : effets des perturbateurs endocriniens sur la reproduction chez le poisson

Nathalie Hinfray , Selim Ait-Aissa , Jean-Marc Porcher , François Brion
Rapport Scientifique INERIS, 2007, 2006-2007, pp.34-36
Journal articles ineris-01869083v1

Expression of zebra fish aromatase cyp19a and cyp19b genes in response to the ligands of estrogen receptor and aryl hydrocarbon receptor.

Ksenia Cheshenko , Francois Brion , Yann Le Page , Nathalie Hinfray , Farzad Pakdel
Toxicological Sciences, 2007, 96 (2), pp.255-67. ⟨10.1093/toxsci/kfm003⟩
Journal articles hal-00140538v1
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Modulation of aromatase activity and mRNA by various selected pesticides in the human choriocarcinoma JEG-3 cell line

Nathalie Laville , Patrick Balaguer , François Brion , Nathalie Hinfray , Claude Casellas
Toxicology, 2006, 228 (1), pp.98-108. ⟨10.1016/j.tox.2006.08.021⟩
Journal articles ineris-00149081v1
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Inhibition of rainbow trout (Oncorhynchus mykiss) P450 aromatase activities in brain and ovarian microsomes by various environmental substances

Nathalie Hinfray , Jean-Marc Porcher , François Brion
Comparative Biochemistry and Physiology - Part C: Toxicology and Pharmacology, 2006, 144 (3), pp.252-262. ⟨10.1016/j.cbpc.2006.09.002⟩
Journal articles ineris-00961905v1
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Brain and gonadal aromatase as potential targets of endocrine disrupting chemicals in a model species, the zebrafish (Danio rerio)

Nathalie Hinfray , Olivier Palluel , Cyril Turies , C. Cousin , Jean-Marc Porcher
Environmental Toxicology, 2006, 21 (4), pp.332-337. ⟨10.1002/tox.20203⟩
Journal articles ineris-00961901v1