nathalie hinfray

Publications

Article dans une revue (33)

Endocrine effects of Imazalil on aromatase expression, vitellogenesis and ovarian histology using cyp19a1a-eGFP-casper transgenic zebrafish Julie de Oliveira,Tu-Ky Ly,Edith Chadili,Violette Thermes,Antoine Mergotet al. Aquatic Toxicology, 2025, 289, pp.107580. ⟨10.1016/j.aquatox.2025.107580⟩ Article dans une revue ineris-05326837v1
A new alternative method using cyp3a65 expression in transgenic zebrafish embryos to assess metabolic endocrine-disrupting chemicals in the intestine Chedi Erradhouani,Florian Geffroy,Benjamin Piccini,Nathalie Hinfray,Edith Chadiliet al. Environment International, 2025, 205, pp.109872. ⟨10.1016/j.envint.2025.109872⟩ Article dans une revue ineris-05330556v1
An end-to-end pipeline based on open source deep learning tools for reliable analysis of complex 3D images of ovaries Manon Lesage,Manon Thomas,Thierry Pécot,Tu-Ky Ly,Nathalie Hinfrayet al. Development (Cambridge, England), 2023, 150 (7), pp.dev201185. ⟨10.1242/dev.201185⟩ Article dans une revue hal-04062159v1
Corrigendum to ‘Refinement of an OECD test guideline for evaluating the effects of endocrine disrupting chemicals on aromatase gene expression and reproduction using novel transgenic cyp19a1a-eGFP zebrafish’ [Aquat. Toxicol. 220 (2020) 105403](S0166445X19308392)(10.1016/j.aquatox.2020.105403) N. Hinfray,Julie de Oliveira,Edith Chadili,Benjamin Piccini,Cyril Turieset al. Aquatic Toxicology, 2022, 247, ⟨10.1016/j.aquatox.2022.106166⟩ Article dans une revue hal-03841956v1
A comparison of behavioral and reproductive parameters between wild-type, transgenic and mutant zebrafish: Could they all be considered the same “zebrafish” for reglementary assays on endocrine disruption? Julie de Oliveira,Edith Chadili,Cyril Turies,François Brion,Xavier Cousinet al. Comparative Biochemistry and Physiology - Part C: Toxicology and Pharmacology, 2021, 239, pp.108879. ⟨10.1016/j.cbpc.2020.108879⟩ Article dans une revue hal-03183773v1
Human and Zebrafish Nuclear Progesterone Receptors Are Differently Activated by Manifold Progestins Clémentine Garoche,Selim Aït-Aïssa,Abdelhay Boulahtouf,Nicolas Creusot,Nathalie Hinfrayet al. Environmental Science and Technology, 2020, 54 (15), pp.9510-9518. ⟨10.1021/acs.est.0c02056⟩ Article dans une revue hal-04707325v1
Refinement of an OECD test guideline for evaluating the effects of endocrine disrupting chemicals on aromatase gene expression and reproduction using novel transgenic cyp19a1a-eGFP zebrafish Julie de Oliveira,Edith Chadili,Benjamin Piccini,Cyril Turies,Emmanuelle Maillot-Maréchalet al. Aquatic Toxicology, 2020, 220, pp.105403. ⟨10.1016/j.aquatox.2020.105403⟩ Article dans une revue ineris-03034495v1
Améliorer les tests de criblage des perturbateurs endocriniens Nathalie Hinfray Les cahiers de la Recherche : Santé, Environnement, Travail, 2019, Les perturbateurs endocriniens, 13, pp.26-28 Article dans une revue anses-02446269v1
Mixture Concentration-Response Modeling Reveals Antagonistic Effects of Estradiol and Genistein in Combination on Brain Aromatase Gene (cyp19a1b) in Zebrafish Nathalie Hinfray,Cleo Tebby,Benjamin Piccini,Gaëlle Bourgine,Selim Ait-Aissaet al. International Journal of Molecular Sciences, 2018, 19 (4), pp.1047. ⟨10.3390/ijms19041047⟩ Article dans une revue hal-01780218v1
Dynamic and differential expression of the gonadal aromatase during the process of sexual differentiation in a novel transgenic cyp19a1a -eGFP zebrafish line Nathalie Hinfray,Frédéric Sohm,Morgane Caulier,Edith Chadili,Benjamin Picciniet al. General and Comparative Endocrinology, 2018, 261, pp.179-189. ⟨10.1016/j.ygcen.2017.06.014⟩ Article dans une revue hal-01548670v1
Les progestatifs, les poissons et les milieux aquatiques : apports du projet ANR « proofs » François Brion,Clémentine Garoche,Nathalie Hinfray,Selim Ait-Aissa Rapport Scientifique INERIS, 2017, 2016-2017, pp.14-15 Article dans une revue ineris-01869652v1
Inhibitory effect of cadmium on estrogen signaling in zebrafish brain and protection by zinc Lina Chouchene,Elisabeth Pellegrini,Marie-Madeleine Gueguen,Nathalie Hinfray,François Brionet al. Journal of Applied Toxicology, 2016, 36 (6), pp.863-871. ⟨10.1002/jat.3285⟩ Article dans une revue hal-01274217v1
Several synthetic progestins disrupt the glial cell specific-brain aromatase expression in developing zebra fish Joel Cano-Nicolau,Clementine Garoche,Nathalie Hinfray,Elisabeth Pellegrini,Noureddine Boujradet al. Toxicology and Applied Pharmacology, 2016, 305, pp.12-21. ⟨10.1016/j.taap.2016.05.019⟩ Article dans une revue hal-01366373v1
Additive effects of levonorgestrel and ethinylestradiol on brain aromatase (cyp19a1b) in zebrafish specific in vitro and in vivo bioassays N. Hinfray,C. Tebby,C. Garoche,B. Piccini,G. Bourgineet al. Toxicology and Applied Pharmacology, 2016, 307, pp.108-114. ⟨10.1016/j.taap.2016.07.023⟩ Article dans une revue hal-01367151v1
Localization of steroidogenic enzymes and Foxl2a in the gonads of mature zebrafish [i](Danio rerio)[/i] Morgane Caulier,François Brion,Edith Chadili,Cyril Turies,Benjamin Picciniet al. Comparative Biochemistry and Physiology - Part A: Molecular and Integrative Physiology, 2015, 188, pp.96-106. ⟨10.1016/j.cbpa.2015.06.016⟩ Article dans une revue hal-01206346v1
Le modèle embryonnaire de poisson zèbre transgénique cyp19a1b-GFP Cléo Tebby,François Brion,Nathalie Hinfray Rapport Scientifique INERIS, 2014, 2013-2014, pp.32-33 Article dans une revue ineris-01869498v1
Effect of in vivo chronic exposure to clotrimazole on zebrafish testis function Damien Baudiffier,Nathalie Hinfray,Catherine Ravaud,Nicolas Creusot,Edith Chadiliet al. Environmental Science and Pollution Research, 2013, 20 (5), pp.2747-2760. ⟨10.1007/s11356-013-1474-7⟩ Article dans une revue ineris-00961800v1
Cyp17a1 and Cyp19a1 in the zebrafish testis are differentially affected by oestradiol Nathalie Hinfray,Rafael Henrique Nobrega,Morgane Caulier,Damien Baudiffier,Emmanuelle Maillot-Marechalet al. Journal of Endocrinology, 2013, 216 (3), pp.375-388. ⟨10.1530/JOE-12-0509⟩ Article dans une revue ineris-00961811v1
17α-Ethinylestradiol and nonylphenol affect the development of forebrain GnRH neurons through an estrogen receptors-dependent pathway. Mélanie Vosges,Olivier Kah,Nathalie Hinfray,Edith Chadili,Yann Le Pageet al. Reproductive Toxicology, 2012, 33 (2), pp.198-204. ⟨10.1016/j.reprotox.2011.04.005⟩ Article dans une revue istex hal-00750365v1
Les effets du clotrimazole sur la stéroïdogenèse testiculaire chez le poisson zèbre Damien Baudiffier,François Brion,Nathalie Hinfray,Jean-Marc Porcher Rapport Scientifique INERIS, 2012, 2011-2012, pp.36-38 Article dans une revue ineris-01869419v1
A critical role of follicle-stimulating hormone (Fsh) in mediating the effect of clotrimazole on testicular steroidogenesis in adult zebrafish Damien Baudiffier,Nathalie Hinfray,Mélanie Vosges,Nicolas Creusot,Edith Chadiliet al. Toxicology, 2012, 298 (1-3), pp.30-39. ⟨10.1016/j.tox.2012.04.012⟩ Article dans une revue istex ineris-00963381v1
Characterization of testicular expression of P450 17alpha-hydroxylase, 17,20-lyase in zebrafish and its perturbation by the pharmaceutical fungicide clotrimazole Nathalie Hinfray,Damien Baudiffier,Marcello C. Leal,Jean-Marc Porcher,Selim Ait-Aissaet al. General and Comparative Endocrinology, 2011, 174 (3), pp.309-317. ⟨10.1016/j.ygcen.2011.09.008⟩ Article dans une revue ineris-00961766v1
Brain cytochrome P450 aromatase activity in roach (Rutilus rutilus) : Seasonal variations and impact of environmental contaminants Perrine Geraudie,Nathalie Hinfray,Marie Gerbron,Jean-Marc Porcher,François Brionet al. Aquatic Toxicology, 2011, 105 (3-4), pp.378-384. ⟨10.1016/j.aquatox.2011.07.009⟩ Article dans une revue istex ineris-00963304v1
Adverse effects in wild fish living downstream from pharmaceutical manufacture discharges Wilfried Sanchez,William Sremski,Benjamin Piccini,Olivier Palluel,Emmanuelle Maillot-Marechalet al. Environment International, 2011, 37 (8), pp.1342-1348. ⟨10.1016/j.envint.2011.06.002⟩ Article dans une revue ineris-00961764v1
Endocrine effects of the tapeworm Ligula Intestinalis in its teleost host, the roach (Rutilis rutilis) Perrine Geraudie,C. Boulange-Lecomte,Marie Gerbron,Nathalie Hinfray,François Brionet al. Parasitology, 2010, 137 (4), pp.697-704. ⟨10.1017/s003118200999151x⟩ Article dans une revue istex ineris-00963236v1
Endocrine disruption in wild populations of chub (Leuciscus cephalus) in contaminated French streams Nathalie Hinfray,Olivier Palluel,Benjamin Piccini,Wilfried Sanchez,Selim Ait-Aissaet al. Science of the Total Environment, 2010, 408 (9), pp.2146-2154. ⟨10.1016/j.scitotenv.2010.01.003⟩ Article dans une revue ineris-00961748v1
Oestrogen-induced androgen insufficiency results in a reduction of proliferation and differentiation of spermatogonia in the zebrafish testis Paul P. de Waal,Marcello C. Leal,Angel Garcia-Lopez,Sergio Liarte,Hugo de Jongeet al. Journal of Endocrinology, 2009, 202, pp.287-297. ⟨10.1677/JOE-09-0050⟩ Article dans une revue ineris-00963210v1
Effect of (xeno)-estrogens on zebrafish P450c17 (C17, 17 alpha-hydroxylase/17, 20-lyase) mRNA and protein expression in gonadal tissue François Brion,Nathalie Hinfray,Olivier Palluel,Julien Maillard,Isabelle Angladeet al. Cybium : Revue Internationale d’Ichtyologie, 2008, 32 (2, suppl. S), pp.245-246 Article dans une revue ineris-00963150v1
Écotoxicologie : effets des perturbateurs endocriniens sur la reproduction chez le poisson Nathalie Hinfray,Selim Ait-Aissa,Jean-Marc Porcher,François Brion Rapport Scientifique INERIS, 2007, 2006-2007, pp.34-36 Article dans une revue ineris-01869083v1
Expression of zebra fish aromatase cyp19a and cyp19b genes in response to the ligands of estrogen receptor and aryl hydrocarbon receptor. Ksenia Cheshenko,Francois Brion,Yann Le Page,Nathalie Hinfray,Farzad Pakdelet al. Toxicological Sciences, 2007, 96 (2), pp.255-67. ⟨10.1093/toxsci/kfm003⟩ Article dans une revue hal-00140538v1
Brain and gonadal aromatase as potential targets of endocrine disrupting chemicals in a model species, the zebrafish (Danio rerio) Nathalie Hinfray,Olivier Palluel,Cyril Turies,C. Cousin,Jean-Marc Porcheret al. Environmental Toxicology, 2006, 21 (4), pp.332-337. ⟨10.1002/tox.20203⟩ Article dans une revue istex ineris-00961901v1
Modulation of aromatase activity and mRNA by various selected pesticides in the human choriocarcinoma JEG-3 cell line Nathalie Laville,Patrick Balaguer,François Brion,Nathalie Hinfray,Claude Casellaset al. Toxicology, 2006, 228 (1), pp.98-108. ⟨10.1016/j.tox.2006.08.021⟩ Article dans une revue ineris-00149081v1
Inhibition of rainbow trout (Oncorhynchus mykiss) P450 aromatase activities in brain and ovarian microsomes by various environmental substances Nathalie Hinfray,Jean-Marc Porcher,François Brion Comparative Biochemistry and Physiology - Part C: Toxicology and Pharmacology, 2006, 144 (3), pp.252-262. ⟨10.1016/j.cbpc.2006.09.002⟩ Article dans une revue ineris-00961905v1

Rapport (1)

Evaluation des effets endocrines des oestrogenes mimétiques et des composés à activité dioxine sur l'expression de gènes cibles et impacts fonctionnels sur la reproduction chez le poisson Francois Brion,Farzad Pakdel,Olivier Kah,Gilles Monod,Nathalie Hinfrayet al. [Rapport de recherche] CV N°05000194, INRA. 2009 Rapport (rapport de recherche) hal-02819706v1