Nathalie Neyroud

Publications

Article dans une revue (37)

Trafficking and Gating Cooperation Between Deficient Nav1.5-mutant Channels to Rescue INa Jérôme Clatot,Alain Coulombe,Isabelle Deschênes,Pascale Guicheney,Nathalie Neyroud Frontiers in Bioscience-Landmark, 2022, 27 (7), pp.209. ⟨10.31083/j.fbl2707209⟩ Article dans une revue hal-03995067v1
Trafficking and Gating Cooperation Between Deficient Nav1.5-mutant Channels to Rescue INa Jérôme Clatot,Alain Coulombe,Isabelle Deschênes,Pascale Guicheney,Nathalie Neyroud Frontiers in Bioscience-Landmark, 2022, 27, ⟨10.31083/j.fbl2707209⟩ Article dans une revue inserm-04021311v1
Generation of a heterozygous SCN5A knockout human induced pluripotent stem cell line by CRISPR/Cas9 edition Marie Gizon,Laëtitia Duboscq-Bidot,Lina El Kassar,Pierre Bobin,Flavie Aderet al. Stem Cell Research, 2022, 60, pp.102680. ⟨10.1016/j.scr.2022.102680⟩ Article dans une revue hal-03549731v1
In vivo Dominant-Negative Effect of an SCN5A Brugada Syndrome Variant Nicolas Doisne,Marta Grauso,Nathalie Mougenot,Michel Clergue,Charlotte Souilet al. Frontiers in Physiology, 2021, 12, pp.661413. ⟨10.3389/fphys.2021.661413⟩ Article dans une revue hal-03342597v1
A Type 2 Ryanodine Receptor Variant in the Helical Domain 2 Associated with an Impairment of the Adrenergic Response Malorie Blancard,Zahia Touat-Hamici,Yuriana Aguilar-Sanchez,Liheng Yin,Guy Vaksmannet al. Journal of Personalized Medicine, 2021, 11 (6), pp.579. ⟨10.3390/jpm11060579⟩ Article dans une revue hal-03278104v1
In vivo Dominant-Negative Effect of an SCN5A Brugada Syndrome Variant Nicolas Doisne,Marta Grauso,Nathalie Mougenot,Michel Clergue,Charlotte Souilet al. Frontiers in Physiology, 2021, 12, ⟨10.3389/fphys.2021.661413⟩ Article dans une revue hal-03261259v1
Inter-Regulation of K v 4.3 and Voltage-Gated Sodium Channels Underlies Predisposition to Cardiac and Neuronal Channelopathies Jérôme Clatot,Nathalie Neyroud,Robert Cox,Charlotte Souil,Jing Huanget al. International Journal of Molecular Sciences, 2020, 21 (14), pp.5057. ⟨10.3390/ijms21145057⟩ Article dans une revue hal-02932372v1
A novel gain‐of‐function mutation in SCN5A responsible for multifocal ectopic Purkinje‐related premature contractions Nicolas Doisne,Victor Waldmann,Alban Redheuil,Xavier Waintraub,Véronique Fressartet al. Human Mutation, 2020, 41 (4), pp.850-859. ⟨10.1002/humu.23981⟩ Article dans une revue hal-02934592v1
Inter-Regulation of Kv4.3 and Voltage-Gated Sodium Channels Underlies Predisposition to Cardiac and Neuronal Channelopathies Jérôme Clatot,Nathalie Neyroud,Robert Cox,Charlotte Souil,Jing Huanget al. International Journal of Molecular Sciences, 2020, 21, ⟨10.3390/ijms21145057⟩ Article dans une revue inserm-04021335v1
A truncating SCN5A mutation combined with genetic variability causes sick sinus syndrome and early atrial fibrillation Azza Ziyadeh-Isleem,Jérôme Clatot,Sabine Duchatelet,Estelle Gandjbakhch,Isabelle Denjoyet al. Heart Rhythm, 2014, 11 (6), pp.1015-1023. ⟨10.1016/j.hrthm.2014.02.021⟩ Article dans une revue hal-02330963v1
Desmosomal Cadherins Are Decreased in Explanted Arrhythmogenic Right Ventricular Dysplasia/Cardiomyopathy Patient Hearts Alexia Vite,Estelle Gandjbakhch,Catherine Prost,Véronique Fressart,Pierre Fouretet al. PLoS ONE, 2013, 8 (9), pp.e75082. ⟨10.1371/journal.pone.0075082⟩ Article dans une revue hal-02330952v1
Dominant-negative effect of SCN5A N-terminal mutations through the interaction of Nav1.5 α-subunits Jérôme Clatot,Azza Ziyadeh-Isleem,Svetlana Maugenre,Isabelle Denjoy,Haiyan Liuet al. Cardiovascular Research, 2012, 96 (1), pp.53-63. ⟨10.1093/cvr/cvs211⟩ Article dans une revue hal-02330941v1
MOG1: a new susceptibility gene for Brugada syndrome. Darouna Kattygnarath,Svetlana Maugenre,Nathalie Neyroud,Elise Balse,Carole Ichaiet al. Circulation: Cardiovascular Genetics, 2011, 4 (3), pp.261-268. ⟨10.1161/CIRCGENETICS.110.959130⟩ Article dans une revue hal-02330925v1
Kv4 Potassium Channels Form a Tripartite Complex With the Anchoring Protein SAP97 and CaMKII in Cardiac Myocytes Saïd El-Haou,Elise Balse,Nathalie Neyroud,Gilles Dilanian,Bruno Gavilletet al. Circulation Research, 2009, 104 (6), pp.758-769. ⟨10.1161/CIRCRESAHA.108.191007⟩ Article dans une revue hal-02330905v1
The anchoring protein SAP97 retains Kv1.5 channels in the plasma membrane of cardiac myocytes Joëlle Abi-Char,Saïd El-Haou,Elise Balse,Nathalie Neyroud,Roger Vranckxet al. AJP - Heart and Circulatory Physiology, 2008, 294 (4), pp.H1851-H1861. ⟨10.1152/ajpheart.01045.2007⟩ Article dans une revue hal-02330886v1
Mutations in the Z-band protein myopalladin gene and idiopathic dilated cardiomyopathy Laetitia Duboscq-Bidot,Peng Xu,Philippe Charron,Nathalie Neyroud,Gilles Dilanianet al. Cardiovascular Research, 2008, 77 (1), pp.118-125. ⟨10.1093/cvr/cvm015⟩ Article dans une revue hal-02330870v1
Heart rate influences on repolarization duration and morphology in symptomatic versus asymptomatic KCNQ1 mutation carriers Fabrice Extramiana,Isabelle Denjoy,Fabio Badilini,Iheb Chabani,Nathalie Neyroudet al. American Journal of Cardiology, 2005, 95 (3), pp.406-409. ⟨10.1016/j.amjcard.2004.09.045⟩ Article dans une revue istex hal-02330856v1
MAGUKs: beyond ionic channel anchoring David Godreau,Nathalie Neyroud,Roger Vranckx,Stéphane Hatem Médecine/Sciences, 2004, 20 (1), pp.84-88. ⟨10.1051/medsci/200420184⟩ Article dans une revue hal-04003484v1
Isoform-Specific Modulation of Voltage-Gated Na + Channels by Calmodulin Isabelle Deschênes,Nathalie Neyroud,Deborah Disilvestre,Eduardo Marban,David Yueet al. Circulation Research, 2002, 90 (4), pp.E49-57. ⟨10.1161/01.res.0000012502.92751.e6⟩ Article dans une revue hal-02330754v1
Somatic Gene Transfer of Tagged K+ Channel Fragments to Probe Trafficking and Electrical Function in Epithelial Cells and Cardiac Myocytes Nathalie Neyroud,I. Deschênes,M. Akao,H.B. Nuss,E. Marbán Journal of Membrane Biology, 2002, 190 (2), pp.133-144. ⟨10.1007/s00232-002-1033-5⟩ Article dans une revue istex hal-02330832v1
Notched T Waves on Holter Recordings Enhance Detection of Patients With LQT2 ( HERG ) Mutations J. Lupoglazoff,I. Denjoy,M. Berthet,Nathalie Neyroud,L. Demayet al. Circulation, 2001, 103 (8), pp.1095-1101. ⟨10.1161/01.cir.103.8.1095⟩ Article dans une revue hal-02330681v1
Novel mutations in KvLQT1 that affect Iks activation through interactions with Isk C. Chouabe,Nathalie Neyroud,P Richard,I Denjoy,B Hainqueet al. Cardiovascular Research, 2000, 45 (4), pp.971-980. ⟨10.1016/s0008-6363(99)00411-3⟩ Article dans une revue hal-02330675v1
[Ventricular repolarization and Holter monitoring. Effect of sympathetic blockage on the QT/RR ratio]. F Extramiana,R Tavernier,P Maison-Blanche,N Neyroud,L Jordaenset al. Archives des Maladies du Coeur et des Vaisseaux, 2000, 93 (11), pp.1277-83 Article dans une revue hal-03999254v1
Mutations in a Dominant-Negative Isoform Correlate with Phenotype in Inherited Cardiac Arrhythmias Raha Mohammad-Panah,Sophie Demolombe,Nathalie Neyroud,Pascale Guicheney,Florence Kyndtet al. American Journal of Human Genetics, 1999, 64 (4), pp.1015-1023. ⟨10.1086/302346⟩ Article dans une revue hal-02330661v1
[Congenital long QT syndrome. The value of genetics in prognostic evaluation]. I Denjoy,J Lupoglazoff,C Donger,M Berthet,P Richardet al. Archives des Maladies du Coeur et des Vaisseaux, 1999, 92 (5), pp.557-63 Article dans une revue hal-03999230v1
Genomic Organization of the KCNQ1 K + Channel Gene and Identification of C-Terminal Mutations in the Long-QT Syndrome Nathalie Neyroud,Pascale Richard,Nicolas Vignier,Claire Donger,Isabelle Denjoyet al. Circulation Research, 1999, 84 (3), pp.290-297. ⟨10.1161/01.res.84.3.290⟩ Article dans une revue hal-02330607v1
QT interval and arrhythmic risk assessment after myocardial infarction Fabrice Extramiana,Nathalie Neyroud,Heikki V. Huikuri,M.Juhani Koistinen,Philippe Coumelet al. American Journal of Cardiology, 1999, 83 (2), pp.266-269. ⟨10.1016/s0002-9149(98)00835-2⟩ Article dans une revue istex hal-02330655v1
Splicing Mutations in KCNQ1: a mutation hot spot at codon 344 that produces in frame transcripts A. Murray,C. Donger,C. Fenske,I. Spillman,P. Richardet al. Circulation, 1999, 100 (10), pp.1077-1084. ⟨10.1161/01.cir.100.10.1077⟩ Article dans une revue hal-02330667v1
Diagnostic performance of QT interval variables from 24-h electrocardiography in the long QT syndrome Nathalie Neyroud,P. Maison-Blanche,I Denjoy,S. Chevret,C Dongeret al. European Heart Journal Supplements, 1998, 19 (1), pp.158-165. ⟨10.1053/euhj.1997.0730⟩ Article dans une revue hal-02330552v1
Heterozygous mutation in the pore of potassium channel gene KvLQT1 causes an apparently normal phenotype in long QT syndrome Nathalie Neyroud,Isabelle Denjoy,Claire Donger,Françoise Gary,Elisabeth Villainet al. European Journal of Human Genetics, 1998, 6 (2), pp.129-133. ⟨10.1038/sj.ejhg.5200165⟩ Article dans une revue hal-02330596v1
[Congenital long QT syndrome]. J Lupoglazoff,I Denjoy,N Neyroud,P Guicheney,A Casasopranaet al. La Presse Médicale, 1998, 27 (21), pp.1029-34 Article dans une revue hal-03999272v1
KVLQT1 C-Terminal Missense Mutation Causes a Forme Fruste Long-QT Syndrome Claire Donger,Isabelle Denjoy,Myriam Berthet,Nathalie Neyroud,Corinne Cruaudet al. Circulation, 1997, 96 (9), pp.2778-2781. ⟨10.1161/01.cir.96.9.2778⟩ Article dans une revue hal-02330550v1
A novel mutation in the potassium channel gene KVLQT1 causes the Jervell and Lange-Nielsen cardioauditory syndrome Nathalie Neyroud,Frédérique Tesson,Isabelle Denjoy,Michel Leibovici,Claire Dongeret al. Nature Genetics, 1997, 15 (2), pp.186-189. ⟨10.1038/ng0297-186⟩ Article dans une revue hal-02330097v1
Properties of KvLQT1 K+ channel mutations in Romano-Ward and Jervell and Lange-Nielsen inherited cardiac arrhythmias C. Chouabe,Nathalie Neyroud,P Guicheney,M. Lazdunski,G. Romeyet al. EMBO Journal, 1997, 16 (17), pp.5472-5479. ⟨10.1093/emboj/16.17.5472⟩ Article dans une revue hal-02330545v1
Different circadian behavior of the apex and the end of the T wave P. Coumel,P. Maison-Blanche,D. Catuli,Nathalie Neyroud,J. Faynet al. Journal of Electrocardiology, 1995, 28, pp.138-142. ⟨10.1016/s0022-0736(95)80039-5⟩ Article dans une revue istex hal-02329255v1
[Dynamics of ventricular repolarisation]. A Leenhardt,P Maison-Blanche,I Denjoy,N Neyroud,D Pellerinet al. Archives des Maladies du Coeur et des Vaisseaux, 1995, 88 Spec No 5, pp.27-33 Article dans une revue hal-04003492v1
[Dynamics of ventricular repolarisation]. A Leenhardt,P Maison-Blanche,I Denjoy,N Neyroud,D Pellerinet al. Archives des Maladies du Coeur et des Vaisseaux, 1995, 88 Spec No 5, pp.27-33 Article dans une revue hal-03999260v1

Communication dans un congrès (7)

A novel approach of therapy using AAVs in a murine model of Scn5a haploinsufficiency. M Ferrand,N Mougenot,Pl Laporte,A Leclerc,V Algalarrondoet al. Printemps de la Cardiologie, SFC, May 2023, Marseille (13), France Communication dans un congrès hal-04003652v1
In vivo dominant-negative effect of an SCN5A Brugada syndrome variant. N Doisne,Marta Grauso,N Mougenot,M Clergue,C Souilet al. Journée de la filière CARDIOGEN, Apr 2021, En ligne (Paris), France Communication dans un congrès hal-04003643v1
CRISPR/Cas9-mediated generation of cardiomyocytes derived from human induced pluripotent stem cells to model SCN5A deficiency. M Gizon,V Fontaine,L Duboscq-Bidot,L El Kassar,K Giraud-Triboultet al. ePrintemps de la Cardiologie, SFC, May 2021, En ligne (Paris), France Communication dans un congrès hal-04003594v1
AAV-mediated gene therapy in a mouse model of Brugada syndrome. N Doisne,Marta Grauso,N Mougenot,M Clergue,A Coulombeet al. IHU ICAN - Les avancées de la Recherche 2018, IHU ICAN, Jan 2018, PARIS, France Communication dans un congrès hal-04003567v1
Recovery of Scn5a-deficient mice cardiac conduction using AAVs. N Doisne,Marta Grauso,N Mougenot,M Clergue,L Fosséet al. Channelopathy meeting, Jun 2018, Chicago, United States Communication dans un congrès hal-04003581v1
A novel RYR2 missense mutation causing catecholaminergic polymorphic ventricular tachycardia and numerous sudden deaths. M Blancard,L Yin,G Vaksmann,N Roux-Buisson,I Denjoyet al. Printemps de la Cardiologie, SFC, Apr 2017, Nantes (44000), France Communication dans un congrès hal-04003560v1
Exploration of the dominant-negative effect of a SCN5A mutation in mice using adeno-associated viruses. N Doisne,Marta Grauso,N Mougenot,M Clergue,A Coulombeet al. Frontiers in CardioVascular Biology, Jul 2016, Florence (IT), Italy Communication dans un congrès hal-04003663v1

Chapitre d'ouvrage (1)

[19] Gene delivery to cardiac muscle Nathalie Neyroud,H Bradley Nuss,Michelle Leppo,Eduardo Marban,J Kevin Donahue Gene delivery to cardiac muscle., 346, pp.323-334, 2002, ⟨10.1016/s0076-6879(02)46064-8⟩ Chapitre d'ouvrage hal-02330727v1