Nicolas AUBERGER Maître de conférences - IC2MP - Université de Poitiers

Identifiants chercheurs

IdHAL :

nicolas-auberger

ORCID :

0000-0002-2076-2112

IdRef :

144721996

VIAF :

201229812

ISNI :

0000000140296502

Présentation

Synthèse multi-étapes de mimes de sucres (iminosucres, C-glycosides) pour l’étude et l’inhibition de glycoenzymes.

Synthèse de mimes de glycoconjugués (glycopeptides, UDP-sucres).

Synthèse de peptides et de peptidomimétiques

Publications

Article dans une revue (22)

Petasis-mediated exo-iminoglycals synthesis from glyconolactams allows access to unprecedented 1-spirocyclopropyl deoxynojirimycin Lilou Chopin,Aurélien Beato,Dylan Yorga,Nicolas Auberger,Jean-Bernard Behret al. Carbohydrate Research, 2025, 560, pp.109765. ⟨10.1016/j.carres.2025.109765⟩ Article dans une revue (article de synthèse) hal-05412880v1
Addition of Lithiated 1,3-Dithiane and Nitronate to Sugar-Derived Imines: Synthesis of Homoiminosugars and Pipecolic Acid Analogues Thanh Van Tran,Jérôme Marrot,Suzuka Yamamoto,Kosuke Yoshimura,Isabelle Gillaizeauet al. Organic Letters, 2025, 27 (20), pp.5068-5073. ⟨10.1021/acs.orglett.5c01061⟩ Article dans une revue hal-05248874v1
Lipopolysaccharide biosynthesis and traffic in the envelope of the pathogen Brucella abortus Caroline Servais,Victoria Vassen,Audrey Verhaeghe,Nina Küster,Elodie Carlieret al. Nature Communications, 2023, 14 (1), pp.911. ⟨10.1038/s41467-023-36442-y⟩ Article dans une revue (article de synthèse) hal-04526179v1
Stereoselective Access to Iminosugar C, C-Glycosides from 6-Azidoketopyranoses Zakaria Debbah,Jérôme C. Marrot,Nicolas Auberger,Jérôme Désiré,Yves Blériot Organic Letters, 2022, 24 (25), pp.4542-4546. ⟨10.1021/acs.orglett.2c01560⟩ Article dans une revue hal-03775104v1
Stereoselective Synthesis of 1- C -Diethylphosphonomethyl and -difluoromethyl Iminosugars from Sugar Lactams Thanh Van Tran,Jérôme Désiré,Nicolas Auberger,Yves Blériot Journal of Organic Chemistry, 2022, 87 (11), pp.7581-7585. ⟨10.1021/acs.joc.2c00835⟩ Article dans une revue hal-03953681v1
Structural variation of the 3-acetamido-4,5,6-trihydroxyazepane iminosugar through epimerization and C -alkylation leads to low micromolar HexAB and NagZ inhibitors J. Bouquet,N. Auberger,R. Ashmus,D. King,A. Bordeset al. Organic & Biomolecular Chemistry, 2022, 20 (3), pp.619-629. ⟨10.1039/d1ob02280f⟩ Article dans une revue hal-04526197v1
Sugar-Derived Amidines and Congeners: Structures, Glycosidase Inhibition and Applications Yves Blériot,Nicolas Auberger,Jérôme Désiré Current Medicinal Chemistry, 2022, 29 (7), pp.1271-1292. ⟨10.2174/0929867329666211222164545⟩ Article dans une revue (article de synthèse) hal-04543430v1
Lewis acid-catalysed nucleophilic opening of a bicyclic hemiaminal followed by ring contraction: Access to functionalized L-idonojirimycin derivatives Nicolas Auberger,Benjamin Onfroy,Nathalie Fontelle,Quentin Foucart,Yves Bleriot Carbohydrate Research, 2019, 472, pp.65-71. ⟨10.1016/j.carres.2018.11.008⟩ Article dans une revue hal-02180492v1
Constrained Cyclic β,γ-Diamino Acids from Glutamic Acid: Synthesis of Both Diastereomers and Unexpected Kinetic Resolution Yang Wan,Nicolas Auberger,Sophie Thétiot-Laurent,Francelin Bouillère,Anaïs Zulaufet al. European Journal of Organic Chemistry, 2018, 2018 (3), pp.329-340. ⟨10.1002/ejoc.201701477⟩ Article dans une revue hal-02997993v1
Multi-Stage Mass Spectrometry Analysis of Sugar-Conjugated β-Turn Structures to be Used as Probes in Autoimmune Diseases Chiara Giangrande,Nicolas Auberger,Cédric Rentier,Anna Maria Papini,Jean-Maurice Malletet al. Journal of The American Society for Mass Spectrometry, 2016, 27 (4), pp.735-747. ⟨10.1007/s13361-015-1321-9⟩ Article dans une revue hal-03150394v1
Efficient synthesis of both diastereomers of β,γ-diamino acids from phenylalanine and tryptophan Nicolas Auberger,Andrii Stanovych,Sophie Thétiot-Laurent,Régis Guillot,Cyrille Kouklovskyet al. Amino Acids, 2016, 48 (9), pp.2237--2242. ⟨10.1007/s00726-016-2262-8⟩ Article dans une revue hal-01460662v1
Demonstration of an oligosaccharide-diphosphodolichol diphosphatase activity whose subcellular localization is different than those of dolichyl-phosphate-dependent enzymes of the dolichol cycle Ahmad Massarweh,Michaël Bosco,Soria Iatmanen-Harbi,Clarice Tessier,Nicolas Aubergeret al. Journal of Lipid Research, 2016, 57 (6), pp.1029-1042. ⟨10.1194/jlr.M067330⟩ Article dans une revue hal-02997964v1
Multi-Stage Mass Spectrometry Analysis of Sugar-Conjugated β-Turn Structures to be Used as Probes in Autoimmune Diseases Chiara Giangrande,Nicolas Auberger,Cédric Rentier,Anna Maria Papini,Jean-Maurice Malletet al. Journal of The American Society for Mass Spectrometry, 2016, 27 (4), pp.735-747. ⟨10.1136/gutjnl-2015-311094⟩ Article dans une revue hal-01303714v1
Synthesis of pyrrolidine-based analogues of 2-acetamidosugars as N-acetyl glucosaminidase inhibitors Anh Tuan Tran,Bo Luo,Jagadeesh Yerri,Nicolas Auberger,Jérôme Désiréet al. Carbohydrate Research, 2015, 409, pp.56-62. ⟨10.1016/j.carres.2015.02.014⟩ Article dans une revue istex hal-01136039v1
Antibody Recognition in Multiple Sclerosis and Rett Syndrome Using a Collection of Linear and Cyclic N-Glucosylated Antigenic Probes Feliciana Real Fernandez,Margherita Di Pisa,Giada Rossi,Nicolas Auberger,Olivier Lequinet al. Biopolymers, 2015, 104 (5, SI), pp.560-576. ⟨10.1002/bip.22677⟩ Article dans une revue hal-01362706v1
γ-Aminoalcohol rearrangement applied to pentahydroxylated azepanes provides pyrrolidines epimeric to homoDMDP Y. Jagadeesh,A. Tran,B. Luo,N. Auberger,J. Désiréet al. Organic & Biomolecular Chemistry, 2015, 13 (11), pp.3446-3456. ⟨10.1039/C5OB00050E⟩ Article dans une revue hal-04543396v1
Synthesis of 1,2-trans-2-Acetamido-2-deoxyhomoiminosugars Yves Blériot,Anh Tuan Tran,Giuseppe Prencipe,Jagadeesh Yerri,Nicolas Aubergeret al. Organic Letters, 2014, 16 (21 ), pp.5516-5519. ⟨10.1021/ol502929h⟩ Article dans une revue hal-01315627v1
Synthesis of 1,2-cis-Homoiminosugars Derived from GlcNAc and GalNAc Exploiting a β-Amino Alcohol Skeletal Rearrangement Yves Blériot,Nicolas Auberger,Jagadeesh Yerri,Charles Gauthier,Giuseppe Prencipeet al. Organic Letters, 2014, 16 (21 ), pp.5512-5515. ⟨10.1021/ol502926f⟩ Article dans une revue hal-01315083v1
Glaser oxidative coupling on peptides: Stabilization of β-turn structure via a 1,3-butadiyne constraint. Nicolas Auberger,Margherita Di Pisa,Maud Larregola,Gérard Chassaing,Elisa Peroniet al. Bioorganic and Medicinal Chemistry, 2014, 22 (24), pp.6924-6932. ⟨10.1016/j.bmc.2014.10.026⟩ Article dans une revue istex hal-01091920v1
Synthesis and biological evaluation of potential new inhibitors of the bacterial transferase MraY with a β-ketophosphonate structure Nicolas Auberger,Rok Frlan,Bayan Al-Dabbagh,Ahmed Bouhss,Muriel Crouvoisieret al. Organic & Biomolecular Chemistry, 2011, 9 (24), pp.8301. ⟨10.1039/c1ob06124k⟩ Article dans une revue hal-02188360v1
Synthesis of a β-Ketophosphonate Bioisostere of UDP- N -acetylglucosamine Nicolas Auberger,Christine Gravier-Pelletier,Yves Le Merrer European Journal of Organic Chemistry, 2009, 2009 (20), pp.3323-3326. ⟨10.1002/ejoc.200900399⟩ Article dans une revue istex hal-02188351v1
A population of thermostable reverse transcriptases evolved from Thermus aquaticus DNA polymerase I by phage display. Sophie Vichier-Guerre,Stéphane Ferris,Nicolas Auberger,Karim Mahiddine,Jean-Luc Jestin Angewandte Chemie International Edition, 2006, 45 (37), pp.6133-7. ⟨10.1002/anie.200601217⟩ Article dans une revue istex pasteur-00166274v1