Access content directly

Nicolas Barnich



Image document

Adherent-invasive E. coli – induced specific IgA limits pathobiont localization to the epithelial niche in the gut

Rika Tanaka , Jin Imai , Hitoshi Tsugawa , Karl Bil Eap , Masaki Yazawa
Frontiers in Microbiology, 2023, 14, ⟨10.3389/fmicb.2023.1031997⟩
Journal articles hal-04181840v1
Image document

Determination of biomarkers associated with neoadjuvant treatment response focusing on colibactin-producing Escherichia coli in patients with mid or low rectal cancer: a prospective clinical study protocol (MICARE)

Christophe Taoum , Guillaume Carrier , Marta Jarlier , Gwenaelle Roche , Johan Gagniere
BMJ Open, 2022, 12 (12), pp.e061527. ⟨10.1136/bmjopen-2022-061527⟩
Journal articles hal-03907379v1
Image document

Epigenetic master regulators HDAC1 and HDAC5 control pathobiont Enterobacteria colonization in ileal mucosa of Crohn’s disease patients

Mélissa Chervy , Adeline Sivignon , Flavie Dambrine , Anthony Buisson , Pierre Sauvanet
Gut microbes, 2022, 14 (1), pp.1-13. ⟨10.1080/19490976.2022.2127444⟩
Journal articles hal-03881385v1

Phage therapy against adherent-invasive E. coli : towards a promising treatment of Crohn’s disease patients?

Delphine Boucher , Nicolas Barnich
Journal of Crohn's and Colitis, 2022, pp.1-2. ⟨10.1093/ecco-jcc/jjac070⟩
Journal articles hal-03746581v1

Anti-TNF agents restrict adherent-invasive Escherichia coli replication within macrophages through modulation of chitinase 3-like 1 in patients with Crohn’s disease

Clara Douadi , Emilie Vazeille , Christophe Chambon , Michel Hébraud , Margot Fargeas
Journal of Crohn's and Colitis, 2022, ⟨10.1093/ecco-jcc/jjab236⟩
Journal articles hal-03529112v1
Image document

An adherent-invasive Escherichia coli -colonized mouse model to evaluate microbiota-targeting strategies in Crohn's disease

Adeline Sivignon , Mélissa Chervy , Caroline Chevarin , Elia Ragot , Elisabeth Billard
Disease Models & Mechanisms, 2022, 15 (10), pp.dmm049707. ⟨10.1242/dmm.049707⟩
Journal articles hal-03907399v1
Image document

Beneficial Effects of Linseed Supplementation on Gut Mucosa-Associated Microbiota in a Physically Active Mouse Model of Crohn's Disease

Claire Plissonneau , Adeline Sivignon , Benoit Chassaing , Frédéric Capel , Vincent Martin
International Journal of Molecular Sciences, 2022, 23 (11), pp.1-21. ⟨10.3390/ijms23115891⟩
Journal articles hal-03677749v1
Image document

The Nutrition-Microbiota-Physical Activity Triad: An Inspiring New Concept for Health and Sports Performance

Nathalie Boisseau , Nicolas Barnich , Christelle Koechlin-Ramonatxo
Nutrients, 2022, 14, pp.1-25. ⟨10.3390/nu14050924⟩
Journal articles hal-03590793v1
Image document

Beneficial Effects of High Intensity Interval Training and/or Linseed Oil Supplementation to Limit Obesity-Induced Oxidative Stress in High Fat Diet-Fed Rats

Carole Groussard , Claire Plissonneau , Laurie Josset , Frédéric Capel , Mathilde Mura
Nutrients, 2021, 13 (10), pp.3531. ⟨10.3390/nu13103531⟩
Journal articles hal-03420264v1
Image document

Beneficial Effects of Natural Mineral Waters on Intestinal Inflammation and the Mucosa-Associated Microbiota

Nicolas Barnich , Michael Rodrigues , Pierre Sauvanet , Caroline Chevarin , Sylvain Denis
International Journal of Molecular Sciences, 2021, 22 (9), pp.4336. ⟨10.3390/ijms22094336⟩
Journal articles hal-03238454v1
Image document

When pathobiont-carbohydrate interaction turns bittersweet!

Nicolas Barnich , Benoit Chassaing
Cellular and Molecular Gastroenterology and Hepatology, 2021, 12 (4), pp.1509-1510. ⟨10.1016/j.jcmgh.2021.08.008⟩
Journal articles hal-03630505v1
Image document

Association of adherent-invasive Escherichia coli with severe gut mucosal dysbiosis in Hong Kong chinese population with Crohn’s disease

Zhilu Xu , Keli Yang , Caroline Chevarin , Jingwan Zhang , Yu Lin
Gut microbes, 2021, 13 (1), pp.1-14. ⟨10.1080/19490976.2021.1994833⟩
Journal articles hal-03482272v1
Image document

Gut microbiota as potential biomarker and/or therapeutic target to improve the management of cancer: focus on colibactin-producing Escherichia coli in colorectal cancer

Julie Veziant , Romain Villéger , Nicolas Barnich , Mathilde Bonnet
Cancers, 2021, 13 (9), pp.1-19. ⟨10.3390/cancers13092215⟩
Journal articles hal-03467852v1
Image document

The TOTUM-63 Supplement and High-Intensity Interval Training Combination Limits Weight Gain, Improves Glycemic Control, and Influences the Composition of Gut Mucosa-Associated Bacteria in Rats on a High Fat Diet

Marine Dupuit , Vivien Chavanelle , Benoit Chassaing , Fanny Perriere , Monique Etienne
Nutrients, 2021, 13 (5), pp.1-24. ⟨10.3390/nu13051569⟩
Journal articles hal-03220475v1
Image document

High-Intensity interval training and α-linolenic acid supplementation improve DHA conversion and increase the abundance of gut mucosa-associated oscillospira bacteria

Claire Plissonneau , Frédéric Capel , Benoit Chassaing , Marine Dupuit , Florie Maillard
Nutrients, 2021, 788, 13 (3), pp.1-19. ⟨10.3390/nu13030788⟩
Journal articles hal-03154591v1
Image document

Faster and less invasive tools to identify patients with ileal colonization by adherent‐invasive E. coli in Crohn's disease

Anthony Buisson , Emilie Vazeille , Mathurin Fumery , Benjamin Pariente , Stéphane Nancey
United European Gastroenterology Journal, 2021, 9 (9), pp.1007 - 1018. ⟨10.1002/ueg2.12161⟩
Journal articles hal-03454309v1
Image document

Differential miRNA-Gene Expression in M Cells in Response to Crohn’s Disease-Associated AIEC

Anaïs Larabi , Laurène Salesse , Charlotte Cordonnier , Lucie Etienne-Mesmin , Nicolas Barnich
Microorganisms, 2020, 8 (8), pp.1205. ⟨10.3390/microorganisms8081205⟩
Journal articles hal-02935826v1

Colibactin‐positive Escherichia coli induce a procarcinogenic immune environment leading to immunotherapy resistance in colorectal cancer

Amélie Lopès , Elisabeth Billard , Al Hassan Casse , Romain Villeger , Julie Veziant
International Journal of Cancer, 2020, 146 (11), pp.3147-3159. ⟨10.1002/ijc.32920⟩
Journal articles hal-02913026v1

DOP49 Quantitative proteomics analysis of macrophages from Crohn’s disease patients and infected with adherent-invasive Escherichia coli

C Douadi , E Vazeille , Christophe Chambon , Michel Hébraud , M Dodel
Journal of Crohn's and Colitis, 2020, 14 (Supplement_1), pp.S087-S088. ⟨10.1093/ecco-jcc/jjz203.088⟩
Journal articles hal-02539567v1

Prognostic value of a combination of innovative factors (gut microbiota, sarcopenia, obesity, metabolic syndrome) to predict surgical/oncologic outcomes following surgery for sporadic colorectal cancer: a prospective cohort study protocol (METABIOTE)

Julie Veziant , Karine Poirot , Caroline Chevarin , Lucie Cassagnes , Pierre Sauvanet
BMJ Open, 2020, 10 (1), pp.e031472. ⟨10.1136/bmjopen-2019-031472⟩
Journal articles hal-02518339v1
Image document

Adherent-Invasive E. coli: Update on the Lifestyle of a Troublemaker in Crohn's Disease

Mélissa Chervy , Nicolas Barnich , Jérémy Denizot
International Journal of Molecular Sciences, 2020, 21 (10), pp.3734. ⟨10.3390/ijms21103734⟩
Journal articles hal-02917127v1
Image document

Methyl-donor supplementation prevents intestinal colonization by Adherent-invasive E. coli in a mouse model of crohn's disease

Elodie Gimier , Mélissa Chervy , Allison Agus , Adeline Sivignon , Elisabeth Billard
Scientific Reports, 2020, 10, pp.12922. ⟨10.1038/s41598-020-69472-3⟩
Journal articles hal-02917129v1

Is BRCA2 involved in early onset colorectal cancer risk?

Mathilde Gay‐bellile , Maud Privat , Alexandra Martins , Sandrine Caputo , Céline Pebrel‐richard
Clinical Genetics, 2020, 97 (4), pp.668-669. ⟨10.1111/cge.13679⟩
Journal articles hal-02518337v1
Image document

Dietary Emulsifiers Directly Impact Adherent-Invasive E. coli Gene Expression to Drive Chronic Intestinal Inflammation

Emilie Viennois , Alexis Bretin , Philip Dubé , Alexander Maue , Charlène J.G. Dauriat
Cell Reports, 2020, 33 (1), pp.108229. ⟨10.1016/j.celrep.2020.108229⟩
Journal articles hal-03042975v1
Image document

Ulcerative Colitis-associated E. coli pathobionts potentiate colitis in susceptible hosts

Hyungjun Yang , Hengameh Chloé Mirsepasi-Lauridsen , Carsten Struve , Joannie M Allaire , Adeline Sivignon
Journal of Immunology, 2020, 12 (1), pp.1-20. ⟨10.1080/19490976.2020.1847976⟩
Journal articles hal-03003143v1

When adherent-invasive E. coli plays with host glycosylation: Does it open new perspectives for therapeutic strategies in Crohn's disease?

Jérémy Denizot , Nicolas Barnich
EBioMedicine, 2020, 55, pp.1-2. ⟨10.1016/j.ebiom.2020.102752⟩
Journal articles hal-02912994v1
Image document

New insights into the interplay between autophagy, gut microbiota and inflammatory responses in IBD

Anaïs Larabi , Nicolas Barnich , Hang Thi Thu Nguyen
Autophagy, inPress, 16 (1), pp.38-51. ⟨10.1080/15548627.2019.1635384⟩
Journal articles hal-03001079v1
Image document

Autophagy of Intestinal Epithelial Cells Inhibits Colorectal Carcinogenesis Induced by Colibactin-Producing Escherichia coli in Apc Mice

Cecily Lucas , Laurène Salesse , My Hanh Thi Hoang , Mathilde Bonnet , Pierre Sauvanet
Gastroenterology, 2020, 158 (5), pp.1373-1388. ⟨10.1053/j.gastro.2019.12.026⟩
Journal articles hal-02518438v1
Image document

Fecal dysbiosis associated with colonic hypersensitivity and behavioral alterations in chronically Blastocystis-infected rats

Manon Defaye , Céline Nourrisson , Elodie Baudu , Amandine Lashermes , Maeva Meynier
Scientific Reports, 2020, 10 (1), pp.9146. ⟨10.1038/s41598-020-66156-w⟩
Journal articles inserm-02884871v1
Image document

Pathogenicity Factors of Genomic Islands in Intestinal and Extraintestinal Escherichia coli

Mickael M. Desvaux , Guillaume Dalmasso , Racha Beyrouthy , Nicolas Barnich , Julien Delmas
Frontiers in Microbiology, 2020, 11, ⟨10.3389/fmicb.2020.02065⟩
Journal articles hal-02948743v1
Image document

Emerging Role of Exosomes in Diagnosis and Treatment of Infectious and Inflammatory Bowel Diseases

Anaïs Larabi , Nicolas Barnich , Hang Thi Thu Nguyen
Cells, 2020, 9 (5), pp.1111. ⟨10.3390/cells9051111⟩
Journal articles hal-03001072v1

Exosomes transfer miRNAs from cell-to-cell to inhibit autophagy during infection with Crohn’s disease-associated adherent-invasive E. coli

Anaïs Larabi , Guillaume Dalmasso , Julien Delmas , Nicolas Barnich , Hang Thi Thu Nguyen
Gut microbes, 2020, 11 (6), pp.1677-1694. ⟨10.1080/19490976.2020.1771985⟩
Journal articles hal-03001063v1

Dietary l-serine confers a competitive fitness advantage to Enterobacteriaceae in the inflamed gut

Sho Kitamoto , Christopher Alteri , Michael Rodrigues , Hiroko Nagao-Kitamoto , Kohei Sugihara
Nature Microbiology, 2020, 5 (1), pp.116-125. ⟨10.1038/s41564-019-0591-6⟩
Journal articles hal-02541666v1

Adaptation of adherent-invasive E. coli to gut environment: Impact on flagellum expression and bacterial colonization ability

Gwladys Sevrin , Sébastien Massier , Benoit Chassaing , Allison Agus , Julien Delmas
Gut microbes, 2020, 11 (3), pp.364-380. ⟨10.1080/19490976.2017.1421886⟩
Journal articles hal-01730371v1
Image document

Study of a classification algorithm for AIEC identification in geographically distinct E. coli strains

Carla Camprubí-Font , Paula Bustamante , Roberto M Vidal , Claire L O'Brien , Nicolas Barnich
Scientific Reports, 2020, 10 (1), pp.8094. ⟨10.1038/s41598-020-64894-5⟩
Journal articles inserm-02865390v1
Image document

TH1 cell-inducing Escherichia coli strain identified from the small intestinal mucosa of patients with Crohn’s disease

Manabu Nagayama , Tomonori Yano , Koji Atarashi , Takeshi Tanoue , Mariko Sekiya
Gut microbes, 2020, 12 (1), pp.1788898. ⟨10.1080/19490976.2020.1788898⟩
Journal articles hal-03042977v1

Prominence of ileal mucosa-associated microbiota to predict postoperative endoscopic recurrence in Crohn’s disease

Harry Sokol , Loic Brot , Carmen Stefanescu , Claire Auzolle , Nicolas Barnich
Gut, 2020, 69 (3), pp.462-472. ⟨10.1136/gutjnl-2019-318719⟩
Journal articles hal-02193634v1

Characterization of mucosa-associated Escherichia coli strains isolated from Crohn’s disease patients in Brazil

Rafaella F. A. Costa , Maria L. A. Ferrari , Marie-Agnès Bringer , Arlette Darfeuille-Michaud , Flaviano S. Martins
BMC Microbiology, 2020, 20 (1), pp.178. ⟨10.1186/s12866-020-01856-x⟩
Journal articles hal-02903480v1
Image document

Crohn’s Disease-Associated Adherent-Invasive Escherichia coli Manipulate Host Autophagy by Impairing SUMOylation

Guillaume Dalmasso , Hang Nguyen , Tiphanie Faïs , Sébastien Massier , Nicolas Barnich
Cells, 2019, 8 (1), pp.35. ⟨10.3390/cells8010035⟩
Journal articles hal-02060087v1
Image document

Intestinal Microbiota: A Novel Target to Improve Anti-Tumor Treatment?

Romain Villeger , Amélie Lopès , Guillaume Carrier , Julie Veziant , Elisabeth Billard
International Journal of Molecular Sciences, 2019, 20 (18), pp.4584. ⟨10.3390/ijms20184584⟩
Journal articles hal-02518541v1

Flagellin-mediated activation of IL-33-ST2 signaling by a pathobiont promotes intestinal fibrosis

Jin Imai , Sho Kitamoto , Kohei Sugihara , Hiroko Kitamoto , Atsushi Hayashi
Mucosal Immunology, 2019, 12 (3), pp.632-643. ⟨10.1038/s41385-019-0138-4⟩
Journal articles hal-02193572v1

T cell clonal expansions in ileal Crohn’s disease are associated with smoking behaviour and postoperative recurrence

Matthieu Allez , Claire Auzolle , Marjolaine Ngollo , Hugo Bottois , Victor Chardiny
Gut, 2019, 9 (1), pp.gutjnl-2018-317878. ⟨10.1136/gutjnl-2018-317878⟩
Journal articles hal-02193601v1
Image document

Metabolic adaptation of adherent-invasive Escherichia coli to exposure to bile salts

Julien Delmas , Lucie Gibold , Tiphanie Faïs , Sylvine Batista , Martin Leremboure
Scientific Reports, 2019, ⟨10.1038/s41598-019-38628-1⟩
Journal articles hal-02060120v1
Image document

Tissue-specific oxidative stress modulation by exercise: A comparison between MICT and HIIT in an obese rat model

Carole Groussard , Florie Maillard , E. Vazeille , Nicolas Barnich , Pascal Sirvent
Oxidative Medicine and Cellular Longevity, 2019, 2019, 11 p. ⟨10.1155/2019/1965364⟩
Journal articles hal-02266297v1
Image document

Association Between Microscopic Lesions at Ileal Resection Margin and Recurrence After Surgery in Patients With Crohn’s Disease

Nassim Hammoudi , Dominique Cazals-Hatem , Claire Auzolle , Charlotte Gardair , Marjolaine Ngollo
Clinical Gastroenterology and Hepatology, 2019, ⟨10.1016/j.cgh.2019.04.045⟩
Journal articles hal-02193633v1
Image document

Preventive Effect of Spontaneous Physical Activity on the Gut-Adipose Tissue in a Mouse Model That Mimics Crohn’s Disease Susceptibility

Florie Maillard , Emilie Vazeille , Pierre Sauvanet , Pascal Sirvent , Richard Bonnet
Cells, 2019, 8 (1), pp.33. ⟨10.3390/cells8010033⟩
Journal articles hal-01982430v1
Image document

AIEC infection triggers modification of gut microbiota composition in genetically predisposed mice, contributing to intestinal inflammation

Alexis Bretin , Cecily Lucas , Anaïs Larabi , Guillaume Dalmasso , Elisabeth Billard
Scientific Reports, 2018, 8 (1), ⟨10.1038/s41598-018-30055-y⟩
Journal articles hal-01897658v1
Image document

Colibactin: More Than a New Bacterial Toxin

Tiphanie Faïs , Julien Delmas , Nicolas Barnich , Richard Bonnet , Guillaume Dalmasso
Toxins, 2018, 10 (4), ⟨10.3390/toxins10040151⟩
Journal articles hal-01796959v1
Image document

Oligomannose-Rich Membranes of Dying Intestinal Epithelial Cells Promote Host Colonization by Adherent-Invasive E. coli

Tetiana Dumych , Nao Yamakawa , Adeline Sivignon , Estelle Garénaux , Stefania Robakiewicz
Frontiers in Microbiology, 2018, 9, ⟨10.3389/fmicb.2018.00742⟩
Journal articles hal-01796957v1

Adherent-invasive Escherichia coli in inflammatory bowel disease

Carolina Palmela , Caroline Chevarin , Zhilu Xu , Joana Torres , Gwladys Sevrin
Gut, 2018, 67 (3), pp.574-587. ⟨10.1136/gutjnl-2017-314903⟩
Journal articles hal-01681169v1
Image document

Prevalence of Yersinia Species in the Ileum of Crohn's Disease Patients and Controls

Guillaume Le Baut , Claire O'Brien , Paul Pavli , Maryline Roy , Philippe Seksik
Frontiers in Cellular and Infection Microbiology, 2018, 8, ⟨10.3389/fcimb.2018.00336⟩
Journal articles hal-01897651v1
Image document

Efficient and reproducible experimental infections of rats with Blastocystis spp.

Manon Defaye , Céline Nourrisson , Elodie Baudu , Ivan Warwzyniak , Virginie Bonnin
PLoS ONE, 2018, 13 (11), pp.1-15. ⟨10.1371/journal.pone.0207669⟩
Journal articles hal-01931278v1
Image document

Deciphering the immune microenvironment of a tissue by digital imaging and cognition network

A. Lopès , Al H. Cassé , E. Billard , E. Boulcourt-Sambou , G. Roche
Scientific Reports, 2018, 8, pp.16692. ⟨10.1038/s41598-018-34731-x⟩
Journal articles hal-01926377v1

Anti-infectious properties of the probiotic Saccharomyces cerevisiae CNCM I-3856 on enterotoxigenic E. coli (ETEC) strain H10407

S. Denis , T Tsilia , N. Ballet , P. Vandekerckove , T. van de Wiele
Applied Microbiology and Biotechnology, 2018, 102 (14), pp.6175-6189. ⟨10.1007/s00253-018-9053-y⟩
Journal articles hal-01809200v1
Image document

Microbial markers in colorectal cancer detection and/or prognosis

Romain Villeger , Amélie Lopès , Julie Veziant , Johan Gagniere , Nicolas Barnich
World Journal of Gastroenterology, 2018, 24 (22), pp.2327 - 2347. ⟨10.3748/wjg.v24.i22.2327⟩
Journal articles hal-01897664v1
Image document

Microbiota, inflammation and colorectal cancer

Cecily Lucas , Nicolas Barnich , Hang Thi Thu Nguyen
International Journal of Molecular Sciences, 2017, 18 (6), ⟨10.3390/ijms18061310⟩
Journal articles hal-01608007v1

Interactions between microsatellite instability and human gut colonization by Escherichia coli in colorectal cancer

Johan Gagniere , Virginie Bonnin , Anne-Sophie Jarrousse , Emilie Cardamone , Allison Agus
Clinical Science, 2017, 131 (6), pp.471 - 485. ⟨10.1042/CS20160876⟩
Journal articles hal-01594568v1
Image document

Enterohemorrhagic Escherichia coli pathogenesis: role of Long polar fimbriae in Peyer's patches interactions

Charlotte Cordonnier , Lucie Etienne-Mesmin , Jonathan Thevenot , Amandine Rougeron , Sandra Renier
Scientific Reports, 2017, 7 (1), pp.1-14. ⟨10.1038/srep44655⟩
Journal articles hal-01607483v1

The presence of adherent-invasive Escherichia coli strains on the surgical specimen is a predictor of severe endoscopic postoperative recurrence in Crohn's disease

N. Barnich , A. Buisson , C. Auzolle , M. Rodrigues , C. Stefanescu
Journal of Crohn's and Colitis, 2017, 11 (1), pp.S475-S476
Journal articles hal-03553322v1

The potential of FimH as a novel therapeutic target for the treatment of Crohn’s disease

Adeline Sivignon , Julie Bouckaert , Julien Bernard , Sebastien G. Gouin , Nicolas Barnich
Expert Opinion on Therapeutic Targets, 2017, 21 (9), pp.837 - 847. ⟨10.1080/14728222.2017.1363184⟩
Journal articles hal-01633566v1

Fecal Matrix Metalloprotease-9 and Lipocalin-2 as Biomarkers in Detecting Endoscopic Activity in Patients With Inflammatory Bowel Diseases

Anthony Buisson , Emilie Vazeille , Régine Minet-Quinard , Marion Goutte , Damien Bouvier
Journal of Clinical Gastroenterology, 2017, 52 (7), pp.E53-E62. ⟨10.1097/MCG.0000000000000837⟩
Journal articles hal-01681173v1

Adherent-Invasive E. coli enhances colonic hypersensitivity and P2X receptors expression during post-infectious period

Amandine Lashermes , Ludivine Boudieu , Julie Barbier , Benoit Sion , Agathe Gelot
Gut microbes, 2017, 9 (1), pp.26-37. ⟨10.1080/19490976.2017.1361091⟩
Journal articles hal-02064637v1
Image document

Bacteriophages targeting adherent invasive Escherichia coli strains as a promising new treatment for Crohn's disease

Matthieu Galtier , Luisa de Sordi , Adeline Sivignon , Amélie de Vallée , Christel Neut
Journal of Crohn's and Colitis, 2017, Advance publication online (7), pp.840-847. ⟨10.1093/ecco-jcc/jjw224⟩
Journal articles pasteur-01538942v1

Macrophages Versus Escherichia coli

Anthony Buisson , Marie-Agnès Bringer , Nicolas Barnich , Emilie Vazeille
Inflammatory Bowel Diseases, 2016, 22 (12), pp.2943 - 2955. ⟨10.1097/MIB.0000000000000946⟩
Journal articles hal-01493355v1

The Vat-AIEC protease promotes crossing of the intestinal mucus layer by Crohn's disease-associated Escherichia coli

Lucie Gibold , Estelle Garénaux , Guillaume Dalmasso , Camille Gallucci , David Cia
Cellular Microbiology, 2016, 18 (5), pp.617 - 631. ⟨10.1111/cmi.12539⟩
Journal articles hal-01926372v1

Certaines bactéries de la flore commensale exacerberaient-elles la carcinogenèse colorectale ?

Jennifer Raisch , Guillaume Dalmasso , Richard Bonnet , Nicolas Barnich , Mathilde Bonnet
Médecine/Sciences, 2016, 32 (2), pp.175-82. ⟨10.1051/medsci/20163202011⟩
Journal articles pasteur-01351541v1

Activation of the EIF2AK4-EIF2A/eIF2 alpha-ATF4 pathway triggers autophagy response to crohn disease-associated adherent-invasive escherichia coli infection

Alexis Bretin , Jessica Carrière , Guillaume Dalmasso , Agnes Bergougnoux , Wafa B'Chir
Autophagy, 2016, 12 (5), pp.770-783. ⟨10.1080/15548627.2016.1156823⟩
Journal articles hal-02640052v1
Image document

Western diet induces a shift in microbiota composition enhancing susceptibility to Adherent-Invasive E. coli infection and intestinal inflammation.

Allison Agus , Jérémy Denizot , Jonathan Thevenot , Margarita Martinez-Medina , Sébastien Massier
Scientific Reports, 2016, 6 (1), pp.19032. ⟨10.1038/srep19032⟩
Journal articles hal-01928173v1

GipA Factor Supports Colonization of Peyerʼs Patches by Crohnʼs Disease-associated Escherichia Coli

Emilie Vazeille , Benoit Chassaing , Anthony Buisson , Anaëlle Dubois , Amélie de Vallée
Inflammatory Bowel Diseases, 2016, 22 (1), pp.68 - 81. ⟨10.1097/MIB.0000000000000609⟩
Journal articles hal-01396555v1

Exosomes released from cells infected with crohn's disease-associated adherent-invasive escherichia coli activate host innate immune responses and enhance bacterial intracellular replication

Jessica Carrière , Alexis Bretin , Arlette Darfeuille-Michaud , Nicolas Barnich , - Hang Thi Thu Nguyen
Inflammatory Bowel Diseases, 2016, 22 (3), pp.516-528. ⟨10.1097/MIB.0000000000000635⟩
Journal articles hal-02638024v1
Image document

Differentiation of Crohn’s Disease-Associated Isolates from Other Pathogenic Escherichia coli by Fimbrial Adhesion under Shear Force

Sabine Szunerits , Oleksandr Zagorodko , Virginie Cogez , Tetiana Dumych , Thibaut Chalopin
Biology, 2016, 5 (2), ⟨10.3390/biology5020014⟩
Journal articles hal-01741244v1
Image document

Oral exposure to environmental pollutant benzo[a]pyrene impacts the intestinal epithelium and induces gut microbial shifts in murine model

Céline Ribière , Pierre Peyret , Nicolas Parisot , Claude Darcha , Pierre Déchelotte
Scientific Reports, 2016, 6, pp.1-11. ⟨10.1038/srep31027⟩
Journal articles hal-02637913v1

Second generation of thiazolylmannosides, FimH antagonists for E. coli-induced Crohn's disease

T. Chalopin , D. Alvarez Dorta , Adeline Sivignon , M. Caudan , T. Dumych
Organic & Biomolecular Chemistry, 2016, 14 (16), pp.3913-3925. ⟨10.1039/c6ob00424e⟩
Journal articles hal-02077029v1

The Antiadhesive Strategy in Crohn′s Disease: Orally Active Mannosides to Decolonize Pathogenic Escherichia coli from the Gut

Dimitri Alvarez Dorta , Adeline Sivignon , Thibaut Chalopin , Tetiana Dumych , Goedele Roos
ChemBioChem, 2016, 17 (10), pp.936-952. ⟨10.1002/cbic.201600018⟩
Journal articles hal-02077036v1
Image document

Gut microbiota imbalance and colorectal cancer.

Johan Gagnière , Jennifer Raisch , Julie Veziant , Nicolas Barnich , Richard Bonnet
World Journal of Gastroenterology, 2016, 22 (2), pp.501-18. ⟨10.3748/wjg.v22.i2.501⟩
Journal articles pasteur-01351170v1

A library of heptyl mannose-functionalized copolymers with distinct compositions, microstructures and neighboring non-sugar motifs as potent antiadhesives of type 1 piliated E. coli

Xibo Yan , Adeline Sivignon , Nicolas Barnich , Sébastien G Gouin , Julie Bouckaert
Polymer Chemistry, 2016, 7 (15), pp.2674-2683. ⟨10.1039/c6py00118a⟩
Journal articles hal-01396465v1

Faecal chitinase 3-like 1 is a reliable marker as accurate as faecal calprotectin in detecting endoscopic activity in adult patients with inflammatory bowel diseases

Anthony Buisson , E. Vazeille , R. Minet-Quinard , M. Goutte , D. Bouvier
Alimentary Pharmacology and Therapeutics, 2016, 43 (10), pp.1069-1079. ⟨10.1111/apt.13585⟩
Journal articles hal-02639968v1

Ribonucleotide reductase NrdR as a novel regulator for motility and chemotaxis duringadherent-invasive escherichia coli infection

Nicolas Dreux , Maria del Mar Cendra , Sébastien Massier , Arlette Darfeuille Michaud , Nicolas Barnich
Infection and Immunity, 2015, 83 (4), pp.1305-1317. ⟨10.1128/IAI.02772-14⟩
Journal articles hal-02640038v1

Erratum to : "Ribonucleotide reductase repressor NrdR as a novel regulator for motility and chemotaxis during adherent-invasive ascherichia coli Infection (vol 83, pg 1305, 2015)"

Nicolas Dreux , Maria del Mar Cendra , Sébastien Massier , Arlette Darfeuille Michaud , Nicolas Barnich
Infection and Immunity, 2015, 83 (10), pp.4174-4174. ⟨10.1128/IAI.00728-15⟩
Journal articles hal-02630205v1

Inhibition profiles of mono- and polyvalent FimH antagonists against 10 different Escherichia coli strains

T. Chalopin , Y. Brissonnet , Adeline Sivignon , D. Deniaud , L. Cremet
Organic & Biomolecular Chemistry, 2015, 13 (46), pp.11369 - 11375. ⟨10.1039/c5ob01581b⟩
Journal articles hal-01931394v1
Image document

Monocyte-derived macrophages from Crohn’s disease patients are impaired in the ability to control intracellular adherent-invasive Escherichia coli and exhibit disordered cytokine secretion profile

Emilie Vazeille , Anthony Buisson , Marie-Agnès Bringer , Marion Goutte , Lemlih Ouchchane
Journal of Crohn's and Colitis, 2015, 9 (5), pp.410-420. ⟨10.1093/ecco-jcc/jjv053⟩
Journal articles hal-01594239v1
Image document

Development of Heptylmannoside-Based Glycoconjugate Antiadhesive Compounds against Adherent-Invasive Escherichia coli Bacteria Associated with Crohn's Disease

Adeline Sivignon , Xibo Yan , Dimitri Alvarez Dorta , Richard Bonnet , Julie Bouckaert
mBio, 2015, 6 (6), pp.e01298-15. ⟨10.1128/mBio.01298-15⟩
Journal articles hal-01265411v1

Analysis of the sigma(E) Regulon in Crohn's Disease-Associated Escherichia coli Revealed Involvement of the waaWVL Operon in Biofilm Formation

Benoit Chassaing , Estelle Garénaux , Jessica Carrière , Nathalie Rolhion , Yann Guerardel
Journal of Bacteriology, 2015, 197 (8), pp.1451-1465. ⟨10.1128/JB.02499-14⟩
Journal articles hal-02631034v1
Image document

Influenza A virus infection of intestinal epithelial cells enhances the adhesion ability of Crohn's disease associated Escherichia coli strains

Marta Aleandri , Maria Pia Conte , Giovanna Simonetti , Simona Panella , Ignacio Celestino
PLoS ONE, 2015, 10 (2), ⟨10.1371/journal.pone.0117005⟩
Journal articles hal-02639201v1

Diet-induced hypoxia responsive element demethylation increases CEACAM6 expression, favouring Crohn's disease-associated Escherichia coli colonisation

Jérémy Denizot , Alexis Desrichard , Allison Agus , Nancy Uhrhammer , Nicolas Dreux
Gut, 2015, 64 (3), pp.428 - 437. ⟨10.1136/gutjnl-2014-306944⟩
Journal articles hal-01928389v1

Glycopolymers as Antiadhesives of E. coil Strains Inducing Inflammatory Bowel Diseases

Xibo Yan , Adeline Sivignon , Nao Yamakawa , Agnès Crepet , Christophe Travelet
Biomacromolecules, 2015, 16 (6), pp.1827-1836. ⟨10.1021/acs.biomac.5b00413⟩
Journal articles hal-01174249v1

Brilliant glyconanocapsules for trapping of bacteria

Xibo Yan , Adeline Sivignon , Pierre Alcouffe , Béatrice Burdin , Sabine Favre-Bonte
Chemical Communications, 2015, 51 (67), pp.13193-13196. ⟨10.1039/c5cc04653j⟩
Journal articles hal-01221578v1

Saccharomyces cerevisiae CNCM I-3856 Prevents Colitis Induced by AIEC Bacteria in the Transgenic Mouse Model Mimicking Crohnʼs Disease

Adeline Sivignon , Amélie de Vallée , Nicolas Barnich , Jérémy Denizot , Claude Darcha
Inflammatory Bowel Diseases, 2015, 21 (2), pp.276 - 286. ⟨10.1097/MIB.0000000000000280⟩
Journal articles hal-01928174v1

In Memoriam, Arlette Darfeuille-Michaud, PhD

Jennifer Raisch , Adeline Sivignon , Benoit Chassaing , Pierre Lapaquette , Sylvie Miquel
Gastroenterology, 2014, 147 (5), pp.943-944. ⟨10.1136/gutjnl-2014-308182⟩
Journal articles hal-01951060v1

Toll-interacting protein modulates colitis susceptibility in mice

Michel H. Maillard , Hristina Bega , Holm H. Uhlig , Nicolas Barnich , Teddy Grandjean
Inflammatory Bowel Diseases, 2014, 20 (4), pp.660-670. ⟨10.1097/MIB.0000000000000006⟩
Journal articles hal-02635358v1
Image document

Understanding Host-Adherent-Invasive Escherichia coli Interaction in Crohn’s Disease: Opening Up New Therapeutic Strategies

Allison Agus , Sébastien Massier , Arlette Darfeuille-Michaud , Elisabeth Billard , Nicolas Barnich
BioMed Research International , 2014, 2014, pp.1 - 16. ⟨10.1155/2014/567929⟩
Journal articles hal-01931428v1

Chitin-binding domains of Escherichia coli ChiA mediate interactions with intestinal epithelial cells in mice with colitis

Daren Low , Hoa T. Tran , In-Ah Lee , Nicolas Dreux , Alan Kamba
Gastroenterology, 2013, 145 (3), pp.602-612. ⟨10.1053/j.gastro.2013.05.017⟩
Journal articles hal-02651692v1

E. coli-mediated gut inflammation in genetically predisposed Crohn's disease patients

N. Barnich , Jérémy Denizot , A. Darfeuille-Michaud
Pathologie Biologie, 2013, 61 (5), pp.e65 - e69. ⟨10.1016/j.patbio.2010.01.004⟩
Journal articles hal-01928194v1
Image document

Comparative genomics of Crohn's disease-associated adherent-invasive Escherichia coli

Claire L O'Brien , Marie-Agnès Bringer , Kathryn E Holt , David M Gordon , Anaëlle L Dubois
Gut, 2013, 66 (8), pp.1382-1389. ⟨10.1136/gutjnl-2015-311059⟩
Journal articles hal-01393979v1
Image document

Point Mutations in FimH Adhesin of Crohn's Disease-Associated Adherent-Invasive Escherichia coli Enhance Intestinal Inflammatory Response

Nicolas Dreux , Jérémy Denizot , Margarita Martinez-Medina , Alexander Mellmann , Maria Billig
PLoS Pathogens, 2013, 9 (1), pp.e1003141. ⟨10.1371/journal.ppat.1003141⟩
Journal articles hal-01928191v1

Western diet induces dysbiosis with increased E coli in CEABAC10 mice , alters host barrier function favouring AIEC colonisation

Margarita Martinez-Medina , Jérémy Denizot , Nicolas Dreux , Frédéric Robin , Elisabeth Billard
Gut, 2013, 63 (1), pp.116 - 124. ⟨10.1136/gutjnl-2012-304119⟩
Journal articles hal-01928324v1
Image document

Importance of Bacteria as Trigger in Inflammatory Bowel Disease

Jérémy Denizot , Nicolas Dreux , Arlette Darfeuille-Michaud , Nicolas Barnich
Journal of Gastrointestinal & Digestive System, 2012, 01, pp.S8. ⟨10.4172/2161-069x.s8-003⟩
Journal articles hal-01928200v1

Adherent-Invasive Escherichia coli Induce Claudin-2 Expression and Barrier Defect in CEABAC10 Mice and Crohnʼs Disease Patients

Jérémy Denizot , Adeline Sivignon , Frederick Barreau , Claude Darcha , Carlos H.F. Chan
Inflammatory Bowel Diseases, 2012, 18 (2), pp.294 - 304. ⟨10.1002/ibd.21787⟩
Journal articles hal-01928192v1

Transient Inability to Manage Proteobacteria Promotes Chronic Gut Inflammation in TLR5-Deficient Mice

Frederic A. Carvalho , Omry Koren , Julia K. Goodrich , Malin E. V. Johansson , Ilke Nalbantoglu
Cell Host and Microbe, 2012, 12 (2), pp.139 - 152. ⟨10.1016/j.chom.2012.07.004⟩
Journal articles hal-02652647v1

Adherent-invasive Escherichia coli phenotype displayed by intestinal pathogenic E. coli strains from cats, dogs, and swine

Margarita Martinez-Medina , Jesús García-Gil , Nicolas Barnich , Lothar H. Wieler , Christa Ewers
Applied and Environmental Microbiology, 2011, 77 (16), pp.5813 - 5817. ⟨10.1128/AEM.02614-10⟩
Journal articles hal-02653076v1
Image document

Abnormally expressed ER stress response chaperone Gp96 in CD favours adherent-invasive Escherichia coli invasion

Nathalie Rolhion , Nicolas Barnich , Marie-Agnès Bringer , Anne-Lise Glasser , Julien Ranc
Growth Development and Aging, 2010, 59 (10), pp.1355-1362. ⟨10.1136/gut.2010.207456⟩
Journal articles hal-01218270v1
Image document

Crohn's disease adherent-invasive Escherichia coli colonize and induce strong gut inflammation in transgenic mice expressing human CEACAM

Frédéric A Carvalho , Nicolas Barnich , Adeline Sivignon , Claude Darcha , Carlos H F Chan
Journal of Experimental Medicine, 2009, 206 (10), pp.2179 - 2189. ⟨10.1084/jem.20090741⟩
Journal articles hal-01931313v1
Image document

Role of bacteria in the etiopathogenesis of inflammatory bowel disease

Nicolas Barnich , Arlette Darfeuille-Michaud
World Journal of Gastroenterology, 2007, 13 (42), pp.5571-5576
Journal articles hal-02669138v1

Lactobacillus acidophilus modulates intestinal pain and induces opioid and cannabinoid receptors

Christel Rousseaux , Xavier Thuru , Agathe Gelot , Nicolas Barnich , Christel Neut
Nature Medicine, 2007, 13 (1), pp.35-37. ⟨10.1038/nm1521⟩
Journal articles hal-02667010v1

Adherent-invasive Escherichia coli and Crohn's disease

Nicolas Barnich , Arlette Darfeuille-Michaud
Current Opinion in Gastroenterology, 2007, 23 (1), pp.16-20
Journal articles hal-02666277v1

CEACAM6 acts as a receptor for adherent-invasive E. coli, supporting ileal mucosa colonization in Crohn disease

Nicolas Barnich , Frederic A. Carvalho , Anne-Lise Glasser , Claude Darcha , Peter Jantscheff
Journal of Clinical Investigation, 2007, 117 (6), pp.1566-1574. ⟨10.1172/JCI30504⟩
Journal articles hal-02666899v1
Image document

HtrA Stress Protein Is Involved in Intramacrophagic Replication of Adherent and Invasive Escherichia coli Strain LF82 Isolated from a Patient with Crohn's Disease

Marie-Agnès Bringer , Nicolas Barnich , Anne-Lise Glasser , Olivier Bardot , Arlette Darfeuille-Michaud
Infection and Immunity, 2005, 73 (2), pp.712 - 721. ⟨10.1128/IAI.73.2.712-721.2005⟩
Journal articles hal-01917182v1

Strong decrease in invasive ability and outer membrane vesicle release in Crohn's disease-associated adherent-invasive Escherichia coli strain LF82 with the yfgL gene deleted

Nathalie Rolhion , Nicolas Barnich , Laurent Claret , Arlette Darfeuille-Michaud
Journal of Bacteriology, 2005, 187 (7), pp.2286-2296. ⟨10.1128/JB.187.7.2286-2296.2005⟩
Journal articles hal-02681129v1

Involvement of lipoprotein NlpI in the virulence of adherent invasive Escherichia coli strain LF82 isolated from a patient with Crohn's disease

Nicolas Barnich , Marie-Agnès Bringer , Laurent Claret , Arlette Darfeuille-Michaud
Infection and Immunity, 2004, 72 (5), pp.2484-2493. ⟨10.1128/IAI.72.5.2484-2493.2004⟩
Journal articles hal-02678710v1

High prevalence of adherent-invasive Escherichia coli associated with ileal mucosa in Crohn's disease

Arlette Darfeuille-Michaud , Jerome Boudeau , Philippe Bulois , Christel Neut , Anne-Lise Glasser
Gastroenterology, 2004, 127 (2), pp.412-421. ⟨10.1053/j.gastro.2004.04.061⟩
Journal articles hal-02683150v1

Presence of adherent Escherichia coli strains in ileal mucosa of patients with Crohn's disease

Arlette Darfeuille-Michaud , Christel Neut , Nicolas Barnich , Emmanuel Lederman , Patrick Di Martino
Gastroenterology, 1998, 115 (6), pp.1405-1413. ⟨10.1016/S0016-5085(98)70019-8⟩
Journal articles hal-01951145v1

Role of adherent and invasive E. coli in Crohn's Disease: Lessons from the postoperative recurrence model

Anthony Buisson , Harry Sokol , Nassim Hammoudi , Stéphane Nancey , Xavier Treton
17. Congress of ECCO, European Crohn’s and Colitis Organisation, Feb 2022, Virtual, Austria
Conference papers hal-03665870v1

Association of High-intensity interval training and linseed oil supplementation change the β-diversity of the gut mucosa-associated microbiota and increase the relative abundance of Oscillospira

Claire Plissonneau , Frédéric Capel , Benoit Chassaing , Marine Dupuit , Florie Maillard
17ème Journée des microbiologistes Clermontois, May 2021, Clermont-Ferrand, France
Conference papers hal-03461939v1

High-intensity interval training and α-linolenic acid supplementation improve DHA conversion and increase the abundance of gut mucosa-associated Oscillospira bacteria.

Claire Plissonneau , Frédéric Capel , Benoit Chassaing , Marine Dupuit , Florie Maillard
Comité scientifique de l’association Bleu-Blanc-Coeur, May 2021, Clermont-Ferrand, France
Conference papers hal-03461962v1

HIIT and flaxseed oil association promote n-3 PUFAs derivatives conversion and modulate gut microbiota composition

Claire Plissonneau , Frédéric Capel , Benoit Chassaing , Marine Dupuit , Florie Maillard
ACAPS, Oct 2021, Montpellier, France
Conference papers hal-03462012v1

Anti-TNF agents restrict adherent-invasive E. coli replication within macrophages through modulation of chitinase 3-like 1 in patients with Crohn’s disease.

C Douadi , Vazeille E. , Christophe Chambon , Michel Hébraud , M Dodel
Digestive Disease Week, May 2021, San Diego, United States
Conference papers hal-03417006v1

Beneficial effect of linseed on the intestinal mucosa associated microbiota to prevent inflammatory and metabolic chronic diseases

Claire Plissonneau , Benoit Chassaing , Frédéric Capel , Guillaume Mairesse , Guillaume Chesneau
12. International Symposium on Gut Microbiology, INRAE ; Rowett Institute UK, Oct 2021, En ligne, France
Conference papers hal-03394821v1

Effects of High-intensity interval training associated with a complementation of flaxseed oil on body composition and metabolic profile in obese rats.

Claire Plissonneau , Frédéric Capel , Benoit Chassaing , Marine Dupuit , Florie Maillard
25th European Congress of Sport Sciences, Sep 2021, Séville, Spain
Conference papers hal-03461991v1

High-intensity interval training and α-linolenic acid supplementation improve DHA conversion and increase the abundance of gut mucosa-associated Oscillospira bacteria.

Claire Plissonneau , Frédéric Capel , Benoit Chassaing , Marine Dupuit , Florie Maillard
Journées de l'Ecole Doctorale, May 2021, Clermont-Ferrand, France
Conference papers hal-03461979v1

Quantitative proteomics analysis of macrophages from Crohn's disease patients and infected with adherents-invasife E. coli

Clara Douadi , Emilie Vazeille , Christine Chambon , Michel Hébraud , Marie Dodel
ECCO, Feb 2020, VIENNE, Austria
Conference papers hal-03043309v1

Identification of EMP2 gene as a new therapeutic target to limit AIEC colonization in CD patients

Mélissa Chervy , Nicolas Barnich , Jérémy Denizot
UEGW 2020, Oct 2020, AMSTERDAM, France
Conference papers hal-03046335v1

Non-invasive identification of adherent-invasive E. coli in patients with Crohn's disease

Anthony Buisson , Emilie Vazeille , Xavier Hébuterne , Mathurin Fumery , Benjamin Pariente
DDW 2020, May 2020, CHICAGO, United States. pp.S044-S045
Conference papers hal-03043456v1

Tryptophan derivatives effects via the AhR signaling pathway modulation on host disturbances after a Citrobacter rodentium infection

Maeva Meynier , Elodie Baudu , Nicolas Barnich , Denis Ardid , Jean-Marc Chatel
CELL SYMPOSIA, May 2020, PARIS, France
Conference papers hal-03045712v1

Epithelial to mesenchymal transition in response to E. coli-induced senescence-associated secretory phenotype induced chemotherapeutic drug resistance

Guillaume Dalmasso , Tiphanie Faïs , Anthony Cougnoux , Nicolas Barnich , Julien Delmas
DDW 2020, May 2020, Chicago, United States
Conference papers hal-02524390v1

Multicenter randomized double-blind cinical trial assessing the benefit of adherent-invasive E. coli eradication in adult ileal and ileo-colonic Crohn disiease: the teorem trial

F. Carbonel , Emilie Vazeille , J Filippi , Y Bouhnik , J Moreau
CCFA, Sep 2020, WASHINGTON, United States
Conference papers hal-03053695v1

The IL-22 pathway as target to relieve visceral pain and animal well-being

Maeva Meynier , Elodie Baudu , Manon Defaye , Y Wawzyniak , Frederic Delbac
ICTRHN, Jun 2020, Clermont-Ferrand, France
Conference papers hal-02524613v1

Colibactin-producing E. coli induces a metabolic reprogramming of colonic epithelial cells toward a pro-carcinogenic metabolism

Romain Villeger , Binta Dieme , Marie Lagree , Julien Delmas , Gwenaëlle Roche
UEGW 2020, Oct 2020, AMSTERDAM, Netherlands
Conference papers hal-03046835v1

Autophagy inhibits colorectal carcinogenesis induced by colibactin-producing escherichia coli

Cecily Lucas , Laurène Salesse , My Hanh Thi Hoang , Mathilde Bonnet , Pierre Sauvanet
Digestive Disease Week (DDW), May 2020, Chicago, United States
Conference papers hal-02527278v1

Colorectal cancer associated-E. coli induce the emergence of chemotherapy-resistant stem cell-like phenotype of host cells

Guillaume Dalmasso , Anthony Cougnoux , Tiphanie Faïs , Hang T.T. Nguyen , Nicolas Barnich
DDW2020, May 2020, Chicago, United States
Conference papers hal-02524369v1

Colorectal cancer associated-E. coli induce the emergence of chemotherapy-resistant stem cell-like phenotype of host cells

Guillaume Dalmasso , Antony Cougnoux , Tiphanie Faïs , Nicolas Barnich , Julien Delmas
15eme congrès national de la SFM, Sep 2019, Paris, France
Conference papers hal-02338700v1

Effet des souches d’E. coli pathogènes sur les défense antioxydantes des entérocytes et impact sur la carcinogenèse colique: approche microscopique

Romain Villéger , Gwenaelle Roche , Johan Gagniere ,