Nicolas JAULIN Nicolas JAULIN

Identifiants chercheurs

IdHAL :

nicolas-jaulin

ORCID :

0000-0002-8127-4323

Présentation

Immunology for gene transfer and Gene Therapy Immunology Core

Publications

Article dans une revue (10)

Advancing liver gene therapy: Enhanced transduction with GalNAc-bioconjugated rAAV capsids Pierre-Alban Lalys,Audrey Bourdon,Mohammed Bouzelha,Dimitri Alvarez-Dorta,Karine Pavageauet al. Biomedicine and Pharmacotherapy, 2025, 189, pp.118300. ⟨10.1016/j.biopha.2025.118300⟩ Article dans une revue hal-05263420v1
Prevalence Study of Cellular Capsid-Specific Immune Responses to AAV2, 4, 5, 8, 9, and rh10 in Healthy Donors Rebecca Xicluna,Allan Avenel,Céline Vandamme,Marie Devaux,Nicolas Jaulinet al. Human Gene Therapy, 2024, 35 (9-10), pp.355-364. ⟨10.1089/hum.2023.225⟩ Article dans une revue hal-04809731v1
Transcriptomic Analysis Reveals the Inability of Recombinant AAV8 to Activate Human Monocyte-Derived Dendritic Cells Samer Masri,Laure Carré,Nicolas Jaulin,Céline Vandamme,Célia Couziniéet al. International Journal of Molecular Sciences, 2023, 24 (13), pp.10447. ⟨10.3390/ijms241310447⟩ Article dans une revue hal-04193929v1
AAV8 locoregional delivery induces long-term expression of an immunogenic transgene in macaques despite persisting local inflammation Gwladys Gernoux,Mickaël Guilbaud,Marie Devaux,Malo Journou,Virginie Pichardet al. Molecular Therapy - Methods and Clinical Development, 2021, 20, pp.660 - 674. ⟨10.1016/j.omtm.2021.02.003⟩ Article dans une revue inserm-03172941v1
Tetramer-Based Enrichment of Preexisting Anti-AAV8 CD8 + T Cells in Human Donors Allows the Detection of a T EMRA Subpopulation Celine Vandamme,Rebecca Xicluna,Leslie Hesnard,Marie Devaux,Nicolas Jaulinet al. Frontiers in Immunology, 2020, 10, pp.3110. ⟨10.3389/fimmu.2019.03110⟩ Article dans une revue inserm-02447186v1
5 years of successful inducible transgene expression following locoregional AAV delivery in nonhuman primates with no detectable immunity Mickaël Guilbaud,Marie Devaux,Célia Couzinié,Johanne Le Duff,Alice Toromanoffet al. Human Gene Therapy, 2019 Article dans une revue inserm-02052292v1
Cross-Packaging and Capsid Mosaic Formation in Multiplexed AAV Libraries Pauline F Schmit,Simon Pacouret,Eric Zinn,Elizabeth Telford,Fotini Nicolaouet al. Molecular Therapy - Methods and Clinical Development, 2019, 17, pp.107-121. ⟨10.1016/j.omtm.2019.11.014⟩ Article dans une revue inserm-02448091v1
Vascular Delivery of Allogeneic MuStem Cells in Dystrophic Dogs Requires Only Short-Term Immunosuppression to Avoid Host Immunity and Generate Clinical/Tissue Benefits Judith Lorant,Thibaut Larcher,Nicolas Jaulin,Benoit Hedan,Aurélie Lardenoiset al. Cell Transplantation, 2018, 27 (7), pp.1096-1110. ⟨10.1177/0963689718776306⟩ Article dans une revue hal-01812518v1
Early Interaction of Adeno-Associated Virus Serotype 8 Vector with the Host Immune System Following Intramuscular Delivery Results in Weak but Detectable Lymphocyte and Dendritic Cell Transduction Gwladys Gernoux,Mickaël Guilbaud,Laurence Dubreil,Thibaut Larcher,Candice Babaritet al. Human Gene Therapy, 2015, 26 (1), pp.1 - 13. ⟨10.1089/hum.2014.070⟩ Article dans une revue inserm-01734763v1
Generation and in vivo evaluation of IL10-treated dendritic cells in a nonhuman primate model of AAV-based gene transfer. Aurélie Moreau,Céline Vandamme,Mercedes Segovia,Marie Devaux,Mickaël Guilbaudet al. Molecular Therapy - Methods and Clinical Development, 2014, 1, ⟨10.1038/mtm.2014.28⟩ Article dans une revue hal-01222897v1

Communication dans un congrès (2)

Locoregional intravenous delivery of AAV vector in macaque results in persistent transgene expression despite a dedicated humoral and cellular immune responses Gwladys Gernoux,Marie Devaux,Laurence Dubreil,Nicolas Jaulin,Mickaël Guilbaudet al. 16. Annual Meeting of the American Society of Gene and Cell Therapy (ASGCT), May 2013, Salt Lake City, Utah, United States Communication dans un congrès hal-02749165v1
Macaque immune responses following AAV-based gene transfer to the skeletal muscle: addressing the method of vector delivery Gwladys Gernoux,Marie Devaux,Laurence Dubreil,Nicolas Jaulin,Mickaël Guilbaudet al. European Society of Gene and Cell Therapy/French Society of Cell and Gene Therapy Collaborative Congress, Oct 2012, Versailles, France Communication dans un congrès hal-02747277v1

Poster de conférence (5)

Human MuStem cells: a cell-based therapy candidate for Duchenne Muscular Dystrophy, with immunomodulatory properties. Judith Lorant,Nicolas Jaulin,Isabelle Leroux,Céline Zuber,Cindy Schlederet al. 5th International congress of Myology, 2016, Lyon, France. 2016 Poster de conférence hal-02740840v1
Human MuStem cells, a promising therapeutic candidate for muscular dystrophies with immunomodulatory properties Judith Lorant,Nicolas Jaulin,Marine Charrier,Blandine Lieubeau-Teillet,Isabelle Lerouxet al. Nantes Actualités Transplantation, Jun 2016, Nantes, France. 2016 Poster de conférence hal-01595625v1
Immunomodulatory properties of human MuStem cells: assessing their impact on adaptive and innate immunity Judith Lorant,Nicolas Jaulin,Isabelle Leroux,Cindy Schleder,Céline Zuberet al. ESGCT and FSGT Collaborative Congress, Sep 2015, Helsinki, Finland. Human Gene Therapy, 26 (10), 2015, Human Gene Therapy Poster de conférence hal-01242346v1
&lt;em&gt;In vitro&lt;/em&gt; and &lt;em&gt;in vivo&lt;/em&gt; characterization of immunomodulatory properties of MuStem cells Judith Lorant,Nicolas Jaulin,Thibaut T. Larcher,Benoît Hédan,Jack-Yves Deschampset al. Annual Congress of the European Society of Gene and Cell Therapy (ESGCT), Oct 2014, The Hague, Netherlands. 2014 Poster de conférence hal-02742740v1
Locoregional intravenous delivery of AAV vector in macaque results in persistent transgene expression despite a dedicated humoral and cellular immune response Gwaldys Gernoux,Marie Devaux,Laurence Dubreil,Nicolas Jaulin,Mickaël Guilbaudet al. 16th annual meeting, May 2013, Salt Lake City, United States. 2013 Poster de conférence hal-01190314v1