Nicolas MACIAN

Publications

Article dans une revue (28)

Two epigenetic markers of the fibromyalgia syndrome: A matched case-control study Marine Delay,Nicolas Macian,Christian Dualé,Bruno Pereira,Youssef Aissouniet al. The Journal of Pain, 2026, 39, pp.105630. ⟨10.1016/j.jpain.2025.105630⟩ Article dans une revue hal-05515070v1
Bioavailable human metabolites from TOTUM-448 (plant-based formulation) maintain liver cell functionality in a hyperlipidic context that drives MASLD onset Fabien Wauquier,Vivien Chavanelle,Annie Bouchard-Mercier,Line Boutin-Wittrant,Yolanda Oteroet al. Scientific Reports, 2025, 16 (1), pp.2748. ⟨10.1038/s41598-025-32556-z⟩ Article dans une revue hal-05462850v1
TOTUM-854 Human Circulating Bioactives Preserve Endothelial Cell Function Fabien Wauquier,Doriane Ripoche,Line Boutin-Wittrant,Yolanda Otero,Stéphanie Krisaet al. Nutrients, 2025, 17 (8), pp.1331. ⟨10.3390/nu17081331⟩ Article dans une revue hal-05410261v1
Systematic review and co-ordinate based meta-analysis to summarize the utilization of functional brain imaging in conjunction with human models of peripheral and central sensitization. Sophie Clarke,Richard Rogers,Vishvarani Wanigasekera,Francesca Fardo,Hossein Piaet al. European Journal of Pain, 2024, 28 (7), pp.1069-1094. ⟨10.1002/ejp.2251⟩ Article dans une revue (article de synthèse) hal-04943626v1
Neuropathic Component Characteristics in Chronic Secondary Musculoskeletal Pain After Postmenopausal Osteoporotic Fractures: A Pilot Cross‐Sectional Study Marie-Eva Pickering,Serge Perrot,Dualé Christian,Véronique Morel,Nicolas Macianet al. Pain Research and Management, 2024, 2024, ⟨10.1155/prm/9766698⟩ Article dans une revue hal-05445246v1
Reduced Production of Pro-Inflammatory and Pro-Catabolic Factors by Human Serum Metabolites Derived from a Patented Saffron Extract Intake Line Pourtau,Fabien Wauquier,Line Boutin-Wittrant,David Gaudout,Benjamin Moraset al. Pharmaceutics, 2024, 16, ⟨10.3390/pharmaceutics16030336⟩ Article dans une revue hal-04643323v1
Neuropathic Component Characteristics in Chronic Secondary Musculoskeletal Pain After Postmenopausal Osteoporotic Fractures: A Pilot Cross‐Sectional Study Marie-Eva Pickering,Serge Perrot,Dualé Christian,Véronique Morel,Nicolas Macianet al. Pain Research and Management, 2024, 2024 (1), ⟨10.1155/prm/9766698⟩ Article dans une revue (article de synthèse) hal-05458321v1
Circulating bioactives resulting from totum-854 absorption in humans protects primary human endothelial cells against lipotoxicity: lessons from an original ex vivo clinical trial Fabien Wauquier,Doriane Ripoche,Line Boutin-Wittrant,Yolanda F Otero,Florian Le Joubiouxet al. Journal of Hypertension -Supplement-, 2023, 41, pp.E308-E308 Article dans une revue hal-04323875v1
Génétique de la douleur chronique Christian Dualé,Pierre Blanc,Nicolas Macian Douleur et Analgésie, 2023, 36 (4), pp.234-49. ⟨10.3166/dea-2022-0275⟩ Article dans une revue hal-04741824v1
Common miRNAs of Osteoporosis and Fibromyalgia: A Review Soline Philippe,Marine Delay,Nicolas Macian,Véronique Morel,Marie-Eva Pickering International Journal of Molecular Sciences, 2023, 24 (17), pp.13513. ⟨10.3390/ijms241713513⟩ Article dans une revue hal-04719274v1
Assessing brain function in stressed healthy individuals following the use of a combination of green tea, Rhodiola, magnesium, and B vitamins: an fMRI study Gisèle Pickering,Lionel Noah,Bruno Pereira,Jonathan Goubayon,Vincent Lerayet al. Frontiers in Nutrition, 2023, 10, pp.1-15. ⟨10.3389/fnut.2023.1211321⟩ Article dans une revue hal-04441458v1
Circulating Human Metabolites Resulting from TOTUM-070 Absorption (a Plant-Based, Polyphenol-Rich Ingredient) Improve Lipid Metabolism in Human Hepatocytes: Lessons from an Original Ex Vivo Clinical Trial Fabien Wauquier,Line Boutin-Wittrant,Stéphanie Krisa,Josep Valls,Cedric Langhiet al. Nutrients, 2023, 15 (8), pp.1903. ⟨10.3390/nu15081903⟩ Article dans une revue hal-04198979v1
Effect of a Combination of Magnesium, B Vitamins, Rhodiola, and Green Tea (L-Theanine) on Chronically Stressed Healthy Individuals—A Randomized, Placebo-Controlled Study Lionel Noah,Veronique Morel,Claire Bertin,Etienne Pouteau,Nicolas Macianet al. Nutrients, 2022, 14 (9), pp.1863. ⟨10.3390/nu14091863⟩ Article dans une revue hal-04256366v1
Benefits of Circulating Human Metabolites from Fish Cartilage Hydrolysate on Primary Human Dermal Fibroblasts, an Ex Vivo Clinical Investigation for Skin Health Applications Fabien Wauquier,Line Boutin-Wittrant,Elodie Bouvret,Julie Le Faouder,Véronique Rouxet al. Nutrients, 2022, 14 (23), pp.5027. ⟨10.3390/nu14235027⟩ Article dans une revue hal-04000218v1
Short-Term Magnesium Therapy Alleviates Moderate Stress in Patients with Fibromyalgia: A Randomized Double-Blind Clinical Trial Nicolas Macian,Christian Dualé,Marion Voute,Vincent Leray,Marion Courrentet al. Nutrients, 2022, 14 (10), pp.2088. ⟨10.3390/nu14102088⟩ Article dans une revue hal-04256395v1
Circulating Human Serum Metabolites Derived from the Intake of a Saffron Extract (Safr’InsideTM) Protect Neurons from Oxidative Stress: Consideration for Depressive Disorders Fabien Wauquier,Line Boutin-Wittrant,Line Pourtau,David Gaudout,Benjamin Moraset al. Nutrients, 2022, 14 (7), pp.1511. ⟨10.3390/nu14071511⟩ Article dans une revue hal-03658538v1
Evaluating the role of orange juice, HESPERidin in vascular HEALTH benefits (HESPER-HEALTH study): protocol for a randomised controlled trial Marie-Anne Verny,Dragan Milenkovic,Nicolas Macian,Bruno Pereira,Rémy Evrardet al. BMJ Open, 2021, 11 (11), pp.e053321. ⟨10.1136/bmjopen-2021-053321⟩ Article dans une revue hal-03462748v1
The Added Value of Sensitivity to Nonnoxious Stimuli to Predict an Individual's Sensitivity to Pain. Christian Dualé,Vincent Leray,Fatiha Giron,Sylvia Boulliau,Nicolas Macianet al. Pain Physician, 2021, 24 (6), pp.E783-E794 Article dans une revue hal-04741735v1
Magnesium for Pain Treatment in 2021? State of the Art Véronique Morel,Marie-Eva Pickering,Jonathan Goubayon,Marguérite Djobo,Nicolas Macianet al. Nutrients, 2021, 13 (5), pp.1397. ⟨10.3390/nu13051397⟩ Article dans une revue hal-04256664v1
Electrochemical Skin Conductance and Quantitative Sensory Testing on Fibromyalgia Gisèle Pickering,Alexanne Achard,Alexandrine Corriger,Sophia Sickout‐arondo,Nicolas Macianet al. Pain Practice, 2020, 20 (4), pp.348-356. ⟨10.1111/papr.12857⟩ Article dans une revue hal-02935679v1
Non‐specific analgesia during a clinical trial in fibromyalgia Christian Dualé,Nicolas Macian,Fatiha Giron,Gisèle Pickering European Journal of Clinical Investigation, 2020, 50 (11), ⟨10.1111/eci.13337⟩ Article dans une revue hal-04741743v1
Effectiveness and safety of 5% lidocaine-medicated plaster on localized neuropathic pain after knee surgery Gisèle Pickering,Marion Voute,Nicolas Macian,Hervé Ganry,Bruno Pereira Pain, 2019, 160 (5), pp.1186-1195. ⟨10.1097/j.pain.0000000000001502⟩ Article dans une revue hal-02325181v1
Hormonal status and cognitivo‐emotional profile in real‐life neuropathic pain patients: a case control study Alexandrine Corriger,Martine Duclos,Jean-Benoît Corcuff,Céline Lambert,Geoffroy Marceauet al. Pain Practice, 2019, 19 (7), ⟨10.1111/papr.12800⟩ Article dans une revue hal-02193914v1
N-acetylcysteine prevents glutathione decrease and does not interfere with paracetamol antinociceptive effect at therapeutic dosage: a randomized double-blind controlled trial in healthy subjects G. Pickering,N. Macian,Isabelle Papet,C. Dualé,C. Coudertet al. Fundamental & Clinical Pharmacology, 2019, 33 (3), pp.303-311. ⟨10.1111/fcp.12437⟩ Article dans une revue hal-01938702v1
Paracetamol and Pain Modulation by TRPV1, UGT2B15, SULT1A1 Genotypes: A Randomized Clinical Trial in Healthy Volunteers Gisèle Pickering,Isabelle Creveaux,Nicolas Macian,Bruno Pereira Pain Medicine, 2019, ⟨10.1093/pm/pnz037⟩ Article dans une revue hal-02325093v1
Milnacipran poorly modulates pain in patients suffering from fibromyalgia: a randomized double-blind controlled study Gisèle Pickering,Nicolas Macian,Noémie Delage,Pascale Picard,Jean-Michel Cardotet al. Drug Design, Development and Therapy, 2018, 12, pp.2485-2496. ⟨10.2147/DDDT.S162810⟩ Article dans une revue hal-01870569v1
Reliability Study in Five Languages of the Translation of the Pain Observational Scale Algoplus Gisèle Pickering,Fiammetta Monacelli,Juan Manuel Pérez-Castejón Garrote,Hirondina Guarda,Luis Batalhaet al. Pain Medicine, 2017, ⟨10.1093/pm/pnw356⟩ Article dans une revue hal-01662587v1
The brain signature of paracetamol in healthy volunteers: a double-blind randomized trial Gisèle Pickering,Adrian Kastler,Nicolas Macian,Bruno Pereira,Romain Valabregueet al. Drug Design, Development and Therapy, 2015, 9, pp.3853-3862. ⟨10.2147/DDDT.S81004⟩ Article dans une revue hal-01214449v1

Communication dans un congrès (2)

Les métabolites sériques humains circulants dérivés de la consommation d'un extrait de safran (Safr'InsideTM) protègent les neurones du stress oxydatif : considérations pour les troubles dépressifs Fabien Wauquier,Line Boutin-Wittrant,Line Pourtau,David Gaudout,Benjamin Moraset al. Journées Françaises de Nutrition, Société Française de Nutrition, Dec 2024, Strasbourg, France Communication dans un congrès hal-04698791v1
Exploring the impact of plant protein vs. animal protein-rich diets in men at cardiometabolic risk: insights from plasma metabolome signatures Gaïa Lépine,Marie Tremblay-Franco,François Mariotti,Jérémie David,Marion Courrentet al. 3rd Nordic Metabolomics Conference, Oct 2023, Trondheim, Norway Communication dans un congrès hal-04354565v1

Thèse (1)

Syndrome fibromyalgique : vers la catégorisation de sous-groupes Nicolas Macian Neurosciences [q-bio.NC]. Université Clermont Auvergne, 2023. Français. ⟨NNT : 2023UCFA0060⟩ Thèse tel-04433514v1

Poster de conférence (2)

Plasma metabolomics reveal metabolite changes compatible with improved metabolic health after 1-month of a plant-rich dietary intervention Gaïa Lépine,Marie Tremblay-Franco,François Mariotti,Jérémie David,Marion Courrentet al. NuGOweek 2023, Sep 2023, Senigallia, Italy Poster de conférence hal-04211898v1
Phase I clinical trial to evaluate TOTUM-63, a botanical complex for managing prediabetes P. Sirvent,M. Bargetto,V. Chavanelle,Nicolas Macian,Sylvia Boulliauet al. 77th Scientific Sessions of American Diabetes Association, Jun 2017, San Diego, United States Poster de conférence hal-01682304v1

Proceedings/Recueil des communications (1)

Circulating Human Metabolites Resulting From TOTUM-070 Absorption (a Plant-Based, Polyphenol-Rich Hypocholesterolemic Ingredient) Improve Lipid Metabolism in Human Hepatocytes: Lessons From an Original ex vivo Clinical Trial Fabien Wauquier,Cédric Langhi,Line Boutin-Wittrant,Yolanda F Otero,Florian Le Joubiouxet al. Circulation, 146, 2022 Proceedings/Recueil des communications hal-04000282v1