Nicolas Savy Nicolas SAVY

Publications

Article dans une revue (50)

Solution methods for a class of finite-horizon vector-valued Markov decision processes Anas Mifrani,Philippe Saint-Pierre,Nicolas Savy INFOR: Information Systems and Operational Research , 2025, ⟨10.1080/03155986.2025.2484050⟩ Article dans une revue hal-04924721v2
Aging modeling and lifetime prediction of a proton exchange membrane fuel cell using an extended Kalman filter Serigne Daouda Pene,Antoine Picot,Fabrice Gamboa,Nicolas Savy,Christophe Turpinet al. Mathematics and Computers in Simulation, 2025, 234, pp.151-168. ⟨10.1016/j.matcom.2025.02.022⟩ Article dans une revue hal-04583935v2
Identification and Economic Evaluation of Differentiated Thyroid Cancer Care Consumption Patterns Using Sequence Analysis Romain Demeulemeester,Pascale Grosclaude,Solange Grunenwald,Philippe Saint-Pierre,Nicolas Savyet al. International Journal of Public Health, 2024, 69, pp.1606664. ⟨10.3389/ijph.2024.1606664⟩ Article dans une revue hal-04844005v1
Comprehensive perioperative blood management in patients undergoing elective bypass cardiac surgery: Benefit effect of health care education and systematic correction of iron deficiency and anemia on red blood cell transfusion Hélène Charbonneau,Stéphanie Savy,Nicolas Savy,Marie Pasquié,Nicolas Mayeuret al. Journal of Clinical Anesthesia, 2024, 98, pp.111560. ⟨10.1016/j.jclinane.2024.111560⟩ Article dans une revue hal-04844113v1
Multicolor flow cytometry in clinical samples for platelet signaling assessment Cedric Garcia,Sebastien Dejean,Nicolas Savy,Jean-Claude Bordet,Jennifer Serieset al. Research and Practice in Thrombosis and Haemostasis, 2023, 7 (4), pp.100180. ⟨10.1016/j.rpth.2023.100180⟩ Article dans une revue hal-04819688v1
A time‐dependent Poisson‐Gamma model for recruitment forecasting in multicenter studies Armando Turchetta,Nicolas Savy,David Stephens,Erica E.M. Moodie,Marina Klein Statistics in Medicine, 2023, 42 (23), pp.4193-4206. ⟨10.1002/sim.9855⟩ Article dans une revue hal-04909845v1
Agent-based modeling in medical research, virtual baseline generator and change in patients’ profile issue Philippe Saint-Pierre,Nicolas Savy The international journal of biostatistics, 2023, 19 (2), pp.333-349. ⟨10.1515/ijb-2022-0112⟩ Article dans une revue hal-04878979v1
Agent based modeling in health care economics: examples in the field of thyroid cancer Romain Demeulemeester,Nicolas Savy,Pascale Grosclaude,Nadège Costa,Philippe Saint-Pierre The international journal of biostatistics, 2023, 19 (2), pp.351-368. ⟨10.1515/ijb-2022-0107⟩ Article dans une revue hal-04474992v1
Economic impact of generic antiretrovirals in France for HIV patients’ care Romain Demeulemeester,Nicolas Savy,Michaël Mounié,Laurent Molinier,Cyrille Delpierreet al. BMC Health Services Research, 2022, 22 (1), pp.567. ⟨10.1186/s12913-022-07859-w⟩ Article dans une revue inserm-03694843v1
OTrecod: An R Package for Data Fusion using Optimal Transportation Theory Grégory Guernec,Valérie Garès,Jérémy Omer,Nicolas Savy,Philippe Saint-Pierre The R Journal, 2022, 14 (4), pp.195 - 222. ⟨10.32614/RJ-2023-006⟩ Article dans une revue hal-03827398v1
Guiding measurement protocols of connected medical devices using digital twins: A statistical methodology applied to detecting and monitoring lymphedema Loic Bethencourt,Walid Dabachine,Vincent Dejouy,Zakaria Lalmiche,Karl Neubergeret al. IEEE Access, 2021, Online ahead of print. ⟨10.1109/ACCESS.2021.3063786⟩ Article dans une revue inserm-03167145v1
Équiper et évaluer un « certificat de compétences cliniques » Olivier Catteau,Anne Mayère,Nicolas Savy,Odile Beyne-Rauzy STICEF (Sciences et Technologies de l'Information et de la Communication pour l'Éducation et la Formation), 2021, Numéro Spécial - Sélection de la conférence EIAH 2019, 27 (2), pp.1-28. ⟨10.23709/sticef.27.2.1⟩ Article dans une revue hal-03186732v1
Patient blood management in elective bypass cardiac surgery: A 2-step single-centre interventional trial to analyse the impact of an educational programme and erythropoiesis stimulation on red blood cell transfusion Hélène Charbonneau,Marie Pasquié,Pierre Berthoumieu,Nicolas Savy,Gérard Autoneset al. Contemporary Clinical Trials Communications, 2020, 19, ⟨10.1016/j.conctc.2020.100617⟩ Article dans une revue hal-04909769v1
On the use of optimal transportation theory to recode variables and application to database merging Valérie Garès,Chloé Dimeglio,Grégory Guernec,Romain Fantin,Benoit Lepageet al. The international journal of biostatistics, 2020, 16 (1), pp.article number : 20180106. ⟨10.1515/ijb-2018-0106⟩ Article dans une revue hal-01905857v2
Real-world costs of illness of Hodgkin and the main B-Cell Non-Hodgkin lymphomas in France Michael Mounie,Nadège Costa,Cécile Conte,Dominique Petiot,Didier Fabreet al. Journal of Medical Economics, 2020, 23 (3), pp.235-242. ⟨10.1080/13696998.2019.1702990⟩ Article dans une revue hal-02533775v1
La fabrique des données à l’épreuve des programmes de big data Nicolas Savy,Anne Mayère,Anja Martin-Scholz,François Lambotte Actualité et dossier en santé publique, 2020, Dossier thématique Données massives et santé publique, 112, pp.27-29 Article dans une revue hal-03352270v1
Additional Costs of Polymyalgia Rheumatica With Giant Cell Arteritis Michael Mounié,Grégory Pugnet,Nicolas Savy,Maryse Lapeyre-Mestre,Laurent Molinieret al. Arthritis Care & Research = Arthritis Care and Research, 2019, 71 (8), pp.1127-1131. ⟨10.1002/acr.23736⟩ Article dans une revue hal-04594053v1
The GMO90+ Project: Absence of Evidence for Biologically Meaningful Effects of Genetically Modified Maize-based Diets on Wistar Rats After 6-Months Feeding Comparative Trial Xavier Coumoul,Rémi Servien,Ludmila Juricek,Yael Kaddouch-Amar,Yannick Lippiet al. Toxicological Sciences, 2019, 168 (2), pp.315-338. ⟨10.1093/toxsci/kfy298⟩ Article dans une revue hal-02196332v1
Évaluation du coût de la prise en charge des patients atteints de Leucémie Myéloïde Chronique (LMC) en Midi-Pyrénées : impact économique des différents Inhibiteurs de Protéines Kinases Michael Mounié,Nadège Costa,Martin Gauthier,Aurore Palmaro,Cyrille Delpierreet al. Journal de gestion et d’économie médicales, 2018, 36 (2), pp.109 Article dans une revue hal-01976692v1
Incremental Costs in Giant Cell Arteritis Michael Mounié,Nadège Costa,Laurent Sailler,Maryse Lapeyre-Mestre,Robert Bourrelet al. Arthritis Care & Research = Arthritis Care and Research, 2018, 70 (7), pp.1074 - 1081. ⟨10.1002/acr.23429⟩ Article dans une revue hal-01864221v1
Stopping or maintaining oral anticoagulation in patients undergoing photoselective vaporization of the prostate (SOAP) surgery for benign prostate obstruction: study protocol for a multicentre randomized controlled trial Hélène Charbonneau,Marie Pasquié,Benoit Peyronnet,Aurélien Descazeaud,Nicolas Barry-Delongchampset al. Trials, 2018, 19 (1), ⟨10.1186/s13063-018-3066-9⟩ Article dans une revue hal-02180512v1
On the Fleming-Harrington test for late effects in prevention randomized controlled trials Valérie Garès,Sandrine Andrieu,Jean-François Dupuy,Nicolas Savy Journal of Statistical Theory and Practice, 2017, 11 (3), pp.418-435. ⟨10.1080/15598608.2017.1295889⟩ Article dans une revue hal-01539213v1
Anticipative Integrals with respect to a filtered Lévy Process and Lévy-Itô decomposition Nicolas Savy,Josep Vives Communications on Stochastic Analysis (COSA), 2017, 11 (1), pp.63-85 Article dans une revue hal-01864321v1
How to deal with the Poisson-gamma model to forecast patients' recruitment in clinical trials when there are pauses in recruitment dynamic? Nathan Minois,Stephanie Savy,Valérie Lauwers-Cances,Sandrine Andrieu,Nicolas Savy Contemporary Clinical Trials Communications, 2017, 5 (23), pp.144-152. ⟨10.1016/j.conctc.2017.01.003⟩ Article dans une revue hal-01864356v1
Interest of the trajectory method for the evaluation of outcomes after in utero drug exposure: example of anxiolytics and hypnotics Caroline Hurault-Delarue,Cécile Chouquet,Nicolas Savy,Isabelle Lacroix,Anna-Belle Beauet al. Pharmacoepidemiology and Drug Safety, 2017, 26 (5), pp.561-569 Article dans une revue hal-01974892v1
The Authors Respond Benoit Lepage,Sébastien Lamy,Nicolas Savy,Thierry Lang Epidemiology, 2017, 28 (3), pp.e29. ⟨10.1097/EDE.0000000000000619⟩ Article dans une revue hal-01864253v1
Using Poisson-gamma model to evaluate the duration of recruitment process when historical trials are available Nathan Minois,Valerie Lauwers-Cances,Stephanie Savy,Michel Attal,Sandrine Andrieuet al. Statistics in Medicine, 2017, 36 (23), pp.3605 - 3620. ⟨10.1002/sim.7365⟩ Article dans une revue hal-01864244v1
Additional costs of polymyalgia rheumatica with giant-cell arteritis Michael Mounié,Grégory Pugnet,Nicolas Savy,Maryse Lapeyre-Mestre,Laurent Molinieret al. Arthritis Care & Research = Arthritis Care and Research, 2016, 11 (3), pp.418-435 Article dans une revue hal-01976676v1
Estimation of a controlled direct effect when an effect of the exposure confounds the mediator-outcome relationship: a comparison of different methods. Benoit Lepage,Dominique Dedieu,Nicolas Savy,Thierry Lang Statistical Methods in Medical Research, 2016, 25 (2), pp.553-570 Article dans une revue hal-01864366v1
How to take into account exposure to drugs over time in pharmacoepidemiology studies of pregnant women? Caroline Hurault-Delarue,Cécile Chouquet,Nicolas Savy,Isabelle Lacroix,Anna-Belle Beauet al. Pharmacoepidemiology and Drug Safety, 2016, 25 (7), pp.770 - 777. ⟨10.1002/pds.4000⟩ Article dans une revue istex hal-01864258v1
An omnibus test for several hazard alternatives in prevention randomized controlled clinical trials Valérie Garès,Sandrine Andrieu,Jean-François Dupuy,Nicolas Savy Statistics in Medicine, 2015, 34 (4), pp.541-557. ⟨10.1002/sim.6366⟩ Article dans une revue istex hal-01120983v1
Big Data et Santé publique : plus que jamais, les enjeux de la connaissance Chloé Dimeglio,Cyrille Delpierre,Nicolas Savy,Thierry Lang Actualité et dossier en santé publique, 2015, 93, pp.5-7 Article dans une revue hal-01864348v1
Estimating the Causal Effect of an Exposure on Change from Baseline Using Directed Acyclic Graphs and Path Analysis Benoit Lepage,Sébastien Lamy,Dominique Dedieu,Nicolas Savy,Thierry Lang Epidemiology, 2015, 26 (1), pp.122 - 129. ⟨10.1097/EDE.0000000000000192⟩ Article dans une revue hal-01864260v1
A comparison of the constant piecewise weighted logrank and Fleming-Harrington tests Valérie Garès,Sandrine Andrieu,Jean-François Dupuy,Nicolas Savy Electronic Journal of Statistics , 2014, 8, pp.841-860. ⟨10.2014/14-EJS911⟩ Article dans une revue hal-01056360v1
Mixed Hidden Markov Model for Heterogeneous Longitudinal Data with Missingness and Errors in the Outcome Variable Dominique Dedieu,Cyrille Delpierre,Sébastien Gadat,Thierry Lang,Benoit Lepageet al. Journal de la Société Française de Statistique, 2014, 105 (1), pp.73-98 Article dans une revue hal-01864353v1
Deleterious impact of feto-maternal MHC compatibility on the success of pregnancy in a macaque model Alice Aarnink,Edward Mee,Nicolas Savy,Nicola Congy-Jolivet,Nicola Roseet al. Immunogenetics, In press, 66 (2), pp.105 - 113. ⟨10.1007/s00251-013-0752-3⟩ Article dans une revue hal-01864282v1
On Ornstein-Uhlenbeck driven by Ornstein-Uhlenbeck processes Bernard Bercu,Frédéric Proïa,Nicolas Savy Statistics and Probability Letters, 2014, 85, pp.36-44. ⟨10.1016/j.spl.2013.11.002⟩ Article dans une revue hal-00915963v1
Estimation of the instantaneous volatility Alexander Alvarez,Fabien Panloup,Monique Pontier,Nicolas Savy Statistical Inference for Stochastic Processes, 2012, 15 (1), pp.27-59. ⟨10.1007/s11203-011-9062-2⟩ Article dans une revue istex hal-00761710v1
Models for patients' recruitment in clinical trials and sensitivity analysis Guillaume Mijoule,Stéphanie Savy,Nicolas Savy Statistics in Medicine, 2012, 31 (16), pp.1655-1674. ⟨10.1002/sim.4495⟩ Article dans une revue istex hal-00942867v1
Use of Cumulative Poisson Probability Distribution as an Estimator of the Recombination Rate in an Expanding Population: Example of the Macaca fascicularis Major Histocompatibility Complex Antoine Blancher,Alice Aarnink,Nicolas Savy,Naoyuki Takahata G3, 2012, 2, pp.123-130. ⟨10.1534/g3.111.001248⟩ Article dans une revue hal-01864345v1
Sharp large deviations for the non-stationary Ornstein-Uhlenbeck process Bernard Bercu,Laure Coutin,Nicolas Savy Stochastic Processes and their Applications, 2012, 122, pp.3393-3424. ⟨10.1016/j.spa.2012.06.006⟩ Article dans une revue hal-00645074v1
Sharp large deviations for the fractional Ornstein-Uhlenbeck process Bernard Bercu,Laure Coutin,Nicolas Savy Theory of Probability and its Applications, 2011, 55 (4), pp.575-610 Article dans une revue hal-00386239v1
Upper bounds on Rubinstein distances on configuration spaces and applications Laurent Decreusefond,Aldéric Joulin,Nicolas Savy Communications on Stochastic Analysis (COSA), 2010, 4 (3), pp.377--399 Article dans une revue hal-00347899v2
Sharp large deviations for the fractional Ornstein - Uhlenbeck process Bernard Bercu,Laure Coutin,Nicolas Savy Teoriya Veroyatnostei i ee Primeneniya, 2010, 55 (4), pp.732-771 Article dans une revue hal-01976746v1
Anticipative calculus with respect to filtered Poisson processes L. Decreusefond,Nicolas Savy Annales de l'Institut Henri Poincaré (B) Probabilités et Statistiques, 2006, 42 (3), pp.343 - 372. ⟨10.1016/j.anihpb.2005.03.005⟩ Article dans une revue hal-01864331v1
A general model based on two mixed Weibull distributions of bacterial resistance, for fitting various shapes of inactivation curves Louis Coroller,Ivan Leguérinel,Eric Mettler,Nicolas Savy,Pierre Mafart Applied and Environmental Microbiology, 2006, 72 (10), pp.6493-6502. ⟨10.1128/AEM.00876-06⟩ Article dans une revue hal-00552093v1
Filtered Brownian motions as weak limit of filtered Poisson processes Laurent Decreusefond,Nicolas Savy Bernoulli, 2005, 11 (2), pp.283-292 Article dans une revue hal-01864326v1
Quantifying the combined effects of the heating time, the temperature and the recovery medium pH on the regrowth lag time of Bacillus cereus spores after a heat treatment Stéphane Gaillard,Ivan Leguérinel,Nicolas Savy,Pierre Mafart International Journal of Food Microbiology, 2005, pp.1-6 Article dans une revue hal-00653930v1
Filtered Brownian motions as weak limit of filtered Poisson processes L. Decreusefond,Nicolas Savy Bernoulli, 2005, 11 (2), pp.283-292 Article dans une revue hal-00841352v1
Survival curves of heated bacterial spores: effect of environmental factors on Weibull parameters Olivier Couvert,Stéphane Gaillard,Nicolas Savy,Pierre Mafart,Ivan Leguérinel International Journal of Food Microbiology, 2005, 101 (1), pp.73-81. ⟨10.1016/j.ijfoodmicro.2004.10.048⟩ Article dans une revue hal-00560873v1

Communication dans un congrès (5)

Fuel cell performance prediction under variable conditions based on Extented Kalman Filter and Random Forests Serigne Daouda Pene,Antoine Picot,Nicolas Savy,Amine Jaafar,Christophe Turpinet al. 2025 IEEE Symposium on Diagnostics for Electric Machines, Power Electronics and Drives (SDEMPED), Aug 2025, Dallas, France. pp.1-6, ⟨10.1109/SDEMPED53223.2025.11154145⟩ Communication dans un congrès hal-05347030v1
Approche hybride pour la prédiction de la dégradation des performances d'une pile à combustible de type PEM basse température Serigne Daouda Pene,Antoine Picot,Fabrice Gamboa,Nicolas Savy,Christophe Turpinet al. Plénières FRH2, 07-11 Octobre, 2024, La grande Motte, France Communication dans un congrès hal-04852650v1
Statistics, philosophy, and health: the SMAC 2021 webconference Nicolas Savy,Erica Em Moodie,Isabelle Drouet,Antoine Chambaz,Bruno Falissardet al. 10èmes journées SMAC, Jun 2021, Toulouse, France. ⟨10.1515/ijb-2022-0017⟩ Communication dans un congrès hal-04027069v1
Causality put to the test of the big data movement: a communicational approach Anja Martin-Scholz,Nicolas Savy,Anne Mayère,François Lambotte Journées du club SMAC – Statistics, Philosophy and Health, Jun 2021, Toulouse, France Communication dans un congrès hal-03352315v1
Dispositif d'évaluation pour un certificat d'aptitudes cliniques : quelles mesures pour quelles compétences ? Olivier Catteau,Odile Beyne Rauzy,Anne Mayère,Nicolas Savy 9e Conference Environnements Informatiques pour l'Apprentissage Humain (EIAH 2019), Jun 2019, Paris, France. pp.157-168 Communication dans un congrès hal-02435357v1

Poster de conférence (2)

Ageing modelling and lifetime prediction of a PEMFC-LT using an Extended Kalman Filter Serigne Daouda Pene,Amine Jaafar,Antoine Picot,Christophe Turpin,Fabrice Gamboaet al. 9th International Conference on Fundamentals & Development of Fuel Cells (FDFC), Sep 2023, Ulm, Germany Poster de conférence hal-04847782v1
Classification of the evolutionary trajectories of cognitive functions Céline Bougel,Sébastien Déjean,Caroline Giulioli,Philippe Saint-Pierre,Nicolas Savyet al. Journées Ouvertes Biologie, Informatique et Mathématiques (JOBIM), Jul 2019, Nantes (44000), France Poster de conférence hal-04315774v1

Chapitre d'ouvrage (3)

Performances of Poisson–Gamma Model for Patients’ Recruitment in Clinical Trials When There Are Pauses in Recruitment or When the Number of Centres is Small Nathan Minois,Guillaume Mijoule,Stéphanie Savy,Valérie Lauwers-Cances,Sandrine Andrieuet al. Springer Proceedings in Mathematics & Statistics book series - Statistics and Simulation - IWS 8, Vienna, Austria, September 2015, 2015 Chapitre d'ouvrage hal-01976829v1
Simulated Clinical Trials: Principle, Good Practices, and Focus on Virtual Patients Generation Nicolas Savy,Stéphanie Savy,Sandrine Andrieu,Sebastien Marque Springer Proceedings in Mathematics & Statistics book series - statistics and simulation - IWS 8, Vienna, Austria, September 2015, 2015 Chapitre d'ouvrage hal-01976838v1
Additive Cost Modelling in Clinical Trial Guillaume Mijoule,Nathan Minois,Vladimir Anisimov,Nicolas Savy Springer Proceedings in Mathematics & Statistics book series (PROMS, volume 114) -, 2014 Chapitre d'ouvrage hal-01976846v1

Autre publication scientifique (1)

Etudes prédictives des processus de vieillissement des piles à combustible à membrane d'échange de protons par approche hybride Serigne Daouda Pene,Antoine Picot,Amine Jaafar,Christophe Turpin,Fabrice Gamboaet al. 2022 Autre publication scientifique hal-04852017v1

Pré-publication, Document de travail (2)

How can methods for classifying and clustering trajectories be used for prevention trials? An example in Alzheimer's disease area Céline Bougel,Sébastien Déjean,Caroline Giulioli,Philippe Saint-Pierre,Nicolas Savyet al. 2025 Pré-publication, Document de travail (preprint/prepublication) hal-05313458v1
A multi-objective model search algorithm for linear regression Anas Mifrani,Philippe Saint-Pierre,Nicolas Savy 2026 Pré-publication, Document de travail (preprint/prepublication) hal-04101559v2

Thèse (1)

Mouvement Brownien Fractionnaire, applications aux télécommunications. Calcul Stochastique relativement à des processus fractionnaires. Nicolas Savy Mathématiques [math]. Université Rennes 1, 2003. Français. ⟨NNT : ⟩ Thèse tel-00003407v1

HDR (1)

Investigations on Stochastic Calculus, Statistics of Processes Applied Statistics for Biology and Medical Research Nicolas Savy Applications [stat.AP]. Université de Toulouse 3 Paul Sabatier, 2014 HDR tel-01645597v1