Nicolas Spinelli

Publications

Communication dans un congrès (10)

Artificial DNAzymes for asymmetric oxidation reactions Quentin Frémi,Caroline Marchi- Delapierre,Stéphane Ménage,Nicolas Spinelli 2026 FrenchBIC Annual Meeting, Mar 2026, Paris, France Communication dans un congrès hal-05584649v1
Artificial DNAzymes for asymmetric oxidation reactions Quentin Frémi,Caroline Marchi- Delapierre,Stéphane Ménage,Nicolas Spinelli 20éme RECOB (REncontres de Chimie Organique Biologique), Mar 2026, Aussois, France Communication dans un congrès hal-05584709v1
Development of a new detection method for small analytes based on the fluorogenic supramolecular assembly of aptamers Rim Karkori,Nicolas Spinelli,Isabelle Baussanne Journée Scientifique du Médicament 2023 : “Contributions of Click Chemistry and Light in Chemical Biology”, DPM, Jun 2023, Grenoble, France Communication dans un congrès hal-04795206v1
Development of a new detection method for small analytes based on the fluorogenic supramolecular assembly of aptamers Rim Karkori,Isabelle Baussanne,Nicolas Spinelli ARCANE Scientific Day, Labex ARCANE, May 2023, Grenoble, France Communication dans un congrès hal-04795236v1
Recent advances in oxidation catalysis with ArMs based on a nickel-binding protein (NikA) and novel RG4s Caroline Marchi- Delapierre,Sarah Lopez,Yoann Colas,Christine Cavazza,Nicolas Spinelliet al. Artificial Proteins in the 21st Century: Designed (Metallo) proteins” Symposium, Apr 2022, Marseille, France Communication dans un congrès hal-04564547v1
Towards a new generation of electrical biosensors based on 2D silicon nanowire networks for DNA and Thrombin detection Monica Vallejo Perez,Céline Ternon,Fanny Morisot,C Gondran,Karine Gorgyet al. Nanotech France 2021, Jun 2021, Paris, France Communication dans un congrès hal-04755031v1
Constrained Oligonucleotides based chiral catalysts Yoann Colas,Caroline Marchi- Delapierre,Nicolas Spinelli 2021 FrenchBIC Meeting, Oct 2021, Obernai, France Communication dans un congrès hal-05045902v1
New generation of FET aptasensors based on silicon nanowire networks for thrombin detection Monica Vallejo Perez,Céline Ternon,Nicolas Spinelli,Xavier Mescot,Valerie Stambouli Réunion d’automne du Club MicroCapteurs Chimiques (CMC2), Nov 2019, Marseille, France Communication dans un congrès hal-04756746v1
Elaboration d’aptacapteurs à nanofils basés sur la détection électrique par effet de champ Monica Vallejo Perez,Céline Ternon,Nicolas Spinelli,Valerie Stambouli Journée scientifique du pôle PEM, IDEX grenoblois, Nov 2019, Grenoble, France Communication dans un congrès hal-04756800v1
Towards Apta-NanoNetFET biosensors Monica Vallejo Perez,F. Morisot,Céline Ternon,N. Spinelli,V. Stambouli 11th Ibero-American Congress on Sensors, Sep 2018, Barcelona, Spain Communication dans un congrès hal-01981225v1

Poster de conférence (9)

Artificial DNAzymes for asymmetric oxidation reactions Quentin Frémi,Caroline Marchi- Delapierre,Stéphane Ménage,Nicolas Spinelli 2025 FrenchBIC Annual Meeting, May 2025, Amboise, France Poster de conférence hal-05454691v1
Artificial DNAzymes for asymmetric oxidation reactions Quentin Frémi,Caroline Marchi- Delapierre,Stéphane Ménage,Nicolas Spinelli 5èmes journées du GDR Chembio (Groupement de recherche Chémobiologie), Jun 2025, Nantes, France Poster de conférence hal-05454655v1
Development of a new detection method for small analytes based on the fluorogenic supramolecular assembly of aptamers Rim Karkori,Nicolas Spinelli,Isabelle Baussanne 31th SCT Young Research Fellows Meeting, Feb 2024, La Tronche, Faculté de Médecine et Pharmacie, Grenoble, France Poster de conférence hal-04794992v1
Development of a new detection method for small analytes based on the fluorogenic supramolecular assembly of aptamers Rim Karkori,Nicolas Spinelli,Isabelle Baussanne 3ème Journée du GDR ChemBio, Jun 2023, Illkirch, Strasbourg, France Poster de conférence hal-04794962v1
Analytical methods for the detection of pollutants in water Imen Kazane,Karine Gorgy,Chantal Gondran,Nicolas Spinelli,Ali Zazaouaet al. The second international Workshop on Chemical Engineering (IWCE23), Dec 2023, Setif, Algeria Poster de conférence hal-04909633v1
Development of a new detection method for small analytes based on the fluorogenic supramolecular assembly of aptamers Rim Karkori,Nicolas Spinelli,Isabelle Baussanne UGA EDCSV PhD Day 2023, Sep 2023, Grenoble, France Poster de conférence hal-04795049v1
Development of a new detection method for small analytes based on the fluorogenic supramolecular assembly of aptamers Rim Karkori,Nicolas Spinelli,Isabelle Baussanne Journée de Printemps SCF section Rhône-Alpes, Jun 2022, Le Bourget du lac - Chambery, France Poster de conférence hal-04795022v1
Constrained oligonucleotides based chiral catalyst Yoann Colas,Stéphane Ménage,Caroline Marchi- Delapierre,Nicolas Spinelli FrenchBIC annual Meeting, Oct 2020, online, France Poster de conférence hal-05052724v1
Constrained oligonucleotides based chiral catalyst Yoann Colas,Stéphane Ménage,Caroline Marchi- Delapierre,Nicolas Spinelli 2nd FrenchBIC summer school on methods for studying metals in biology (METBIO), Oct 2019, Carry-le-Rouet et Marseille, France Poster de conférence hal-05052709v1

Article dans une revue (42)

Aptasensors based on silicon nanowire field-effect transistors for electrical detection of thrombin Rony Midahuen,Valerie Stambouli,Caroline Fontelaye,Guillaume Nonglaton,Nicolas Spinelliet al. Microelectronic Engineering, 2024, 286, pp.112130. ⟨10.1016/j.mee.2023.112130⟩ Article dans une revue cea-04778501v1
Use of Constrained G-Quadruplexes for Enantioselective Sulfoxidation Site Mapping Yoann Colas,Stéphane Ménage,Caroline Marchi- Delapierre,Nicolas Spinelli ChemCatChem, 2024, 16 (1), pp.e202300914. ⟨10.1002/cctc.202300914⟩ Article dans une revue hal-04246624v1
Aptamer conjugated Si nanowire network/poly(pyrrole)-NTA structure for electrochemical sensing Monica Vallejo-Perez,Essohanam Beke,Chantal Gondran,Karine Gorgy,Isabelle Gélardet al. Sensing and Bio-Sensing Research, 2023, 42, pp.100593. ⟨10.1016/j.sbsr.2023.100593⟩ Article dans une revue hal-04272147v1
Conformational transition in SPR experiments: impact of spacer length, immobilization mode and aptamer density on signal sign and amplitude Marina Pons,Marine Perenon,Hugues Bonnet,Emilie Gillon,Celio Valléeet al. Analyst, 2022, 19 (147), pp.4197-4205. ⟨10.1039/D2AN00824F⟩ Article dans une revue hal-03813142v1
Negative SPR Signals during Low Molecular Weight Analyte Recognition H. Bonnet,L. Coche-Guérente,E. Defrancq,N. Spinelli,A. van Der Heydenet al. Analytical Chemistry, 2021, 93 (8), pp.4134-4140. ⟨10.1021/acs.analchem.1c00071⟩ Article dans une revue hal-03177913v1
Recent progress in the design of G-quadruplex–based electrochemical aptasensors Jérôme Dejeu,Angéline van Der Heyden,Nicolas Spinelli,Eric Defrancq,Liliane Coche-Guérente Current Opinion in Electrochemistry, 2021, 30, pp.100812. ⟨10.1016/j.coelec.2021.100812⟩ Article dans une revue hal-03338912v1
Direct Detection of Low Molecular Weight Compounds in 2D and 3D Aptasensors by Biolayer Interferometry Anthony Vignon,Arthur Flaget,Maxime Michelas,Mehdi Deghdir,Éric Defrancqet al. ACS Sensors, 2020, 5 (8), pp.2326-2330. ⟨10.1021/acssensors.0c00925⟩ Article dans une revue hal-02917003v1
Optimization of GOPS-Based Functionalization Process and Impact of Aptamer Grafting on the Si Nanonet FET Electrical Properties as First Steps towards Thrombin Electrical Detection Monica Vallejo-Perez,Céline Ternon,Nicolas Spinelli,Fanny Morisot,Christoforos Theodorouet al. Nanomaterials, 2020, 10 (9), pp.1842. ⟨10.3390/nano10091842⟩ Article dans une revue hal-02978359v1
Influence of Aptamer Surface Coverage on Small Target Recognition: A SPR and QCM-D Comparative Study Hannah Macdonald,Hugues Bonnet,Angéline van Der Heyden,Eric Defrancq,Nicolas Spinelliet al. Journal of Physical Chemistry C, 2019, 123 (22), pp.13561-13568. ⟨10.1021/acs.jpcc.9b00845⟩ Article dans une revue hal-02180487v1
Influence of Aptamer Surface Coverage on Small Target Recognition: A SPR and QCM-D Comparative Study Hannah Macdonald,Hugues Bonnet,Angéline van der Heyden,Eric Defrancq,Nicolas Spinelliet al. Journal of Physical Chemistry C, 2019, 123 (22), pp.13561-13568. ⟨10.1021/acs.jpcc.9b00845⟩ Article dans une revue hal-04405856v1
Impact of Conformational Transitions on SPR Signals—Theoretical Treatment and Application in Small Analytes/Aptamer Recognition Jérôme Dejeu,Hugues Bonnet,Nicolas Spinelli,Eric Defrancq,Liliane Coche-Guérenteet al. Journal of Physical Chemistry C, 2018, 122 (37), pp.21521-21530. ⟨10.1021/acs.jpcc.8b07298⟩ Article dans une revue hal-04405867v1
Impact of Conformational Transitions on SPR Signals—Theoretical Treatment and Application in Small Analytes/Aptamer Recognition Jérôme Dejeu,Hugues Bonnet,Nicolas Spinelli,Eric Defrancq,Liliane Coche-Guerenteet al. Journal of Physical Chemistry C, 2018, 122 (37), pp.21521-21530. ⟨10.1021/acs.jpcc.8b07298⟩ Article dans une revue hal-02180482v1
The pKa value of the proximal water molecule trans to a high-valent MnV=O porphyrin: Towards the control of reactivity by pH Laurie Saint-Germes,Laure Bar,Jérôme Dejeu,Nicolas Spinelli,Eric Defrancqet al. Dalton Transactions, 2017, 46 (36), pp.12088-12094. ⟨10.1039/C7DT01829K⟩ Article dans une revue hal-01649404v1
Highly Sensitive Bisphenol-A Electrochemical Aptasensor Based on Poly(Pyrrole-Nitrilotriacetic Acid)-Aptamer Film Imen Kazane,Karine Gorgy,Chantal Gondran,Nicolas Spinelli,Ali Zazouaet al. Analytical Chemistry, 2016, 88 (14), pp.7268 - 7273. ⟨10.1021/acs.analchem.6b01574⟩ Article dans une revue hal-01644665v1
A label-free photoelectrochemical cocaine aptasensor based on an electropolymerized ruthenium-intercalator complex Fatima Haddache,Alan Le Goff,Nicolas Spinelli,Priyanka Gairola,Karine Gorgyet al. Electrochimica Acta, 2016, 219, pp.82 - 87. ⟨10.1016/j.electacta.2016.09.127⟩ Article dans une revue istex hal-01644537v1
Prefolded Synthetic G-Quartets Display Enhanced Bioinspired Properties Theodore Flack,Thibaut Constantin,Sylvain Penasse,Jérôme Dejeu,Béatrice Gennaroet al. Chemistry - A European Journal, 2016, 22 (5), pp.1760 - 1767. ⟨10.1002/chem.201504572⟩ Article dans une revue istex hal-01400347v1
Construction of anti-parallel G-quadruplexes through sequential templated click Romaric Bonnet,Thomas Lavergne,Béatrice Gennaro,Nicolas Spinelli,Eric Defrancq Chemical Communications, 2015, 51 (23), pp.4850-4853. ⟨10.1039/C4CC09744K⟩ Article dans une revue hal-02178767v1
Macrocyclic Host-Dye Reporter for Sensitive Sandwich-Type Fluorescent Aptamer Sensor Cheng Yang,Nicolas Spinelli,Sandrine Perrier,Eric Defrancq,Eric Peyrin Analytical Chemistry, 2015, 87 (6), pp.3139 - 3143. ⟨10.1021/acs.analchem.5b00341⟩ Article dans une revue hal-01651412v1
Sensor Based on Aptamer Folding to Detect Low-Molecular Weight Analytes Alina Osypova,Dhruv Thakar,Jérôme Dejeu,Hugues Bonnet,Angéline van Der Heydenet al. Analytical Chemistry, 2015, 87 (15), pp.7566 - 7574. ⟨10.1021/acs.analchem.5b01736⟩ Article dans une revue hal-01651120v1
A multi-ligation strategy for the synthesis of heterofunctionalized glycosylated scaffolds Baptiste Thomas,Michele Fiore,Gour Chand Daskhan,Nicolas Spinelli,Olivier Renaudet Chemical Communications, 2015, 51 (25), pp.5436 - 5439. ⟨10.1039/c4cc05451b⟩ Article dans une revue hal-01650732v1
Label-Free Photoelectrochemical Detection of Double-Stranded HIV DNA by Means of a Metallointercalator-Functionalized Electrogenerated Polymer Fatima Haddache,Alan Le goff,Bertrand Reuillard,Karine Gorgy,Chantal Gondranet al. Chemistry - A European Journal, 2014, 20 (47), pp.15555 - 15560. ⟨10.1002/chem.201404335⟩ Article dans une revue istex hal-01652231v1
Surface-immobilized DNAzyme-type biocatalysis Loïc Stefan,Thomas Lavergne,Nicolas Spinelli,Eric Defrancq,David Monchaud Nanoscale, 2014, 6 (5), ⟨10.1039/c3nr05954e⟩ Article dans une revue hal-01652423v1
Synthesis and characterization of oligonucleotide conjugates bearing electroactive labels Julie Moreau,Nabil Dendane,Bernd Schöllhorn,Nicolas Spinelli,Claire Faveet al. Bioorganic and Medicinal Chemistry Letters, 2013, 23 (4), pp.955 - 958. ⟨10.1016/j.bmcl.2012.12.057⟩ Article dans une revue istex hal-01653056v1
Label-free impedimetric thrombin sensor based on poly(pyrrole-nitrilotriacetic acid)-aptamer film Hui Xu,Karine Gorgy,Chantal Gondran,Alan Le Goff,Nicolas Spinelliet al. Biosensors and Bioelectronics, 2013, 41, pp.90 - 95. ⟨10.1016/j.bios.2012.07.044⟩ Article dans une revue istex hal-01652825v1
Glycoclusters on oligonucleotide and PNA scaffolds: synthesis and applications Nicolas Spinelli,Eric Defrancq,François Morvan Chemical Society Reviews, 2013, 42, pp.4557-4573. ⟨10.1039/c2cs35406c⟩ Article dans une revue hal-00822875v1
Electrogenerated trisbipyridyl Ru(II)-/nitrilotriacetic-polypyrene copolymer for the easy fabrication of label-free photoelectrochemical immunosensor and aptasensor: Application to the determination of thrombin and anti-cholera toxinantibody Yao Wenjuan,Alan Le Goff,Nicolas Spinelli,Michael Holzinger,Guo-Wang Diaoet al. Biosensors and Bioelectronics, 2013, 42, pp.556 - 562. ⟨10.1016/j.bios.2012.11.013⟩ Article dans une revue istex hal-01652746v1
Closer to nature: an ATP-driven bioinspired catalytic oxidation process Loïc Stefan,Damien Duret,Nicolas Spinelli,Eric Defrancq,David Monchaud Chemical Communications, 2013, 49 (15), pp.1500. ⟨10.1039/C2CC38317A⟩ Article dans une revue hal-02125740v1
High affinity glycodendrimers for the lectin LecB from &lt;i&gt;Pseudomonas aeruginosa&lt;/i&gt; Nathalie Berthet,Baptiste Thomas,Isabelle Bossu,Emilie Dufour,Emilie Gillonet al. Bioconjugate Chem., 2013, pp.1598-1611. ⟨10.1021/bc400239m⟩ Article dans une revue hal-00903491v1
Click–click chemistry on a peptidic scaffold for easy access to tetrameric DNA structures Romaric Bonnet,Pierre Murat,Nicolas Spinelli,Eric Defrancq Chemical Communications, 2012, 48 (48), ⟨10.1039/c2cc32010j⟩ Article dans une revue hal-01654796v1
The Use of a Peptidic Scaffold for the Formation of Stable Guanine Tetrads: Control of a H-bonded Pattern in Water Pierre Murat,Béatrice Gennaro,Julian Garcia,Nicolas Spinelli,Pascal Dumyet al. Chemistry - A European Journal, 2011, 17 (21), pp.5791 - 5795. ⟨10.1002/chem.201003556⟩ Article dans une revue istex hal-01655632v1
Oligonucleotide sequential bis-conjugation via click-oxime and click-Huisgen procedures. Albert Meyer,Nicolas Spinelli,Pascal Dumy,Jean-Jacques Vasseur,François Morvanet al. Journal of Organic Chemistry, 2010, 75, pp.3927-3930. ⟨10.1021/jo100599m⟩ Article dans une revue hal-00519475v1
Molecular engineering of biomolecules for nanobio-sciences Olivier Renaudet,Julian Garcia,Didier Boturyn,Nicolas Spinelli,Eric Defrancqet al. International Journal of Nanotechnology, 2010, 7 (4/5/6/7/8), ⟨10.1504/IJNT.2010.031742⟩ Article dans une revue hal-01658284v1
Template-Assembled Synthetic G-Quadruplex (TASQ): A Useful System for Investigating the Interactions of Ligands with Constrained Quadruplex Topologies Pierre Murat,Romaric Bonnet,Angéline Van der heyden,Nicolas Spinelli,Pierre Labbéet al. Chemistry - A European Journal, 2010, 16 (20), pp.6106 - 6114. ⟨10.1002/chem.200903456⟩ Article dans une revue istex hal-01658627v1
Efficient conjugation of oligonucleotides through aromatic oxime formation Pierre Murat,Nicolas Spinelli,Pascal Dumy,Eric Defrancq Bioorganic and Medicinal Chemistry Letters, 2009, 19 (23), pp.6534 - 6537. ⟨10.1016/j.bmcl.2009.10.048⟩ Article dans une revue istex hal-01658963v1
A Novel Conformationally Constrained Parallel G Quadruplex Pierre Murat,Delphine Cressend,Nicolas Spinelli,Angéline van der Heyden,Pierre Labbéet al. ChemBioChem, 2008, 9 (16), pp.2588-2591. ⟨10.1002/cbic.200800457⟩ Article dans une revue hal-04823402v1
New solid support for the synthesis of 3 '-oligonucleotide conjugates through glyoxylic oxime bond formation Nicolas Spinelli,Om Prakash Edupuganti,Eric Defrancq,Pascal Dumy Organic Letters, 2007, 9, pp.219-222. ⟨10.1021/ol062607b⟩ Article dans une revue hal-00169469v1
Synthesis and electropolymerization studies of water-soluble pyrrole-ferrocene derivatives towards biochip device application C. Farre,N. Spinelli,Alexandra Bouchet,C.A. Marquette,B. Mandrandet al. Synthetic Metals, 2007, 157 (2-3), pp.125-133 Article dans une revue hal-00287095v1
Aldehydic Oligonucleotide: A Key Intermediate for the Preparation of Oligonucleotide Conjugates Through Oxime Bond Formation Nicolas Spinelli,Yogendra Singh,Éric Defrancq,Pascal Dumy Nucleosides, Nucleotides and Nucleic Acids, 2007, 26 (8-9), pp.883-887. ⟨10.1080/15257770701505436⟩ Article dans une revue hal-04823327v1
The first automated synthesis of ferrocene-labelled phosphorothioate DNA probe: A new potential tool for the fabrication of DNA microarrays. Hugues Brisset,Aude-Emmanuelle Navarro,Nicolas Spinelli,Carole Chaix,Bernard Mandrand Biotechnology Journal, 2006, 1, pp.95-98. ⟨10.1002/biot200500004⟩ Article dans une revue hal-00021563v1
Characterization of PEDOT film functionalized with a series of automated synthesis ferrocenyl-containing oligonucleotides Aude-Emmanuelle Navarro,Frédéric Fages,Corinne Moustrou,Hugues Brisset,Nicolas Spinelliet al. Tetrahedron, 2005, 61 (16), pp.3947-3952. ⟨10.1016/j.tet.2005.02.058⟩ Article dans une revue istex hal-03409069v1
Automated synthesis of new ferrocenyl-modified oligonucleotides: study of their properties in solution A.-E. Navarro,Nicolas Spinelli,Corinne Moustrou,Carole Chaix,Bernard Mandrandet al. Nucleic Acids Research, 2004, 32 (17), pp.5310-5319. ⟨10.1093/nar/gkh874⟩ Article dans une revue hal-03409350v1
Supported synthesis of ferrocene modified oligonucleotides as new electroactive DNA probes Aude-Emmanuelle Navarro,Nicolas Spinelli,Carole Chaix,Corinne Moustrou,Bernard Mandrandet al. Bioorganic and Medicinal Chemistry Letters, 2004, 14 (10), pp.2439-2441. ⟨10.1016/j.bmcl.2004.03.016⟩ Article dans une revue istex hal-03409059v1