Olivier Biondi

Publications

Article dans une revue (18)

Drug Candidate BIO101 for Spinal Muscular Atrophy as Monotherapy or Combined With the Antisense Oligonucleotide ASO‐10‐27 Cynthia Bézier,Steve Cottin,Parvin Nazari Hashemi,Mirella El Khoury,Zoé Clercet al. Journal of Cachexia, Sarcopenia and Muscle, 2025, 16 (5), pp.e70104. ⟨10.1002/jcsm.70104⟩ Article dans une revue hal-05453886v1
Modelling energy metabolism dysregulations in neuromuscular diseases: A case study of calpainopathy Camille Siharath,Olivier Biondi,Sabine Peres Heliyon, 2024, 10 (24), pp.e40918. ⟨10.1016/j.heliyon.2024.e40918⟩ Article dans une revue hal-04845028v1
The analysis of the skeletal muscle metabolism is crucial for designing optimal exercise paradigms in type 2 diabetes mellitus Elias Abi Akar,Laure Weill,Mirella El Khoury,Cédric Caradeuc,Gildas Berthoet al. Molecular Medicine, 2024, 30 (1), pp.80. ⟨10.1186/s10020-024-00850-7⟩ Article dans une revue hal-05316643v1
Dysregulation of muscle cholesterol transport in amyotrophic lateral sclerosis D. Sapaly,F. Cheguillaume,L. Weill,Z. Clerc,O. Biondiet al. Brain - A Journal of Neurology , 2024, Brain, 148 (3), p.788-802. ⟨10.1093/brain/awae270⟩ Article dans une revue hal-04977711v1
NADPH oxidase 4 inhibition is a complementary therapeutic strategy for spinal muscular atrophy Mirella El Khoury,Olivier Biondi,Gaelle Bruneteau,Delphine Sapaly,Sabrina Bendriset al. Frontiers in Cellular Neuroscience, 2023, 17, ⟨10.3389/fncel.2023.1242828⟩ Article dans une revue hal-04495927v1
Activating ATF6 in spinal muscular atrophy promotes SMN expression and motor neuron survival through the IRE1α‐XBP1 pathway Domenico d'Amico,Olivier Biondi,Camille Januel,Cynthia Bezier,Delphine Sapalyet al. Neuropathology and Applied Neurobiology, 2022, 48 (5), pp.e12816. ⟨10.1111/nan.12816⟩ Article dans une revue inserm-04385529v1
Effect of Monoclonal Antibody Blockade of Long Fragment Neurotensin on Weight Loss, Behavior, and Metabolic Traits After High-Fat Diet Induced Obesity Zherui Wu,Nicolas Stadler,Amazigh Abbaci,Jin Liu,Agnès Boullieret al. Frontiers in Endocrinology, 2021, 12, pp.739287. ⟨10.3389/fendo.2021.739287⟩ Article dans une revue hal-03406993v1
Running and Swimming Differently Adapt the BDNF/TrkB Pathway to a Slow Molecular Pattern at the NMJ Laia Just-Borràs,Víctor Cilleros-Mañé,Erica Hurtado,Olivier Biondi,Frédéric Charbonnieret al. International Journal of Molecular Sciences, 2021, 22 (9), pp.4577. ⟨10.3390/ijms22094577⟩ Article dans une revue hal-04466203v1
Low-Intensity Running and High-Intensity Swimming Exercises Differentially Improve Energy Metabolism in Mice With Mild Spinal Muscular Atrophy Léo Houdebine,Domenico d'Amico,Jean Bastin,Farah Chali,Céline Desseilleet al. Frontiers in Physiology, 2019, 10, pp.1258. ⟨10.3389/fphys.2019.01258⟩ Article dans une revue inserm-02893893v1
Small-molecule flunarizine increases SMN protein in nuclear Cajal bodies and motor function in a mouse model of spinal muscular atrophy Delphine Sapaly,Matthieu Dos Santos,Perrine Delers,Olivier Biondi,Gwendoline Quérolet al. Scientific Reports, 2018, 8 (1), pp.2075. ⟨10.1038/s41598-018-20219-1⟩ Article dans une revue pasteur-02090360v1
Specific Physical Exercise Improves Energetic Metabolism in the Skeletal Muscle of Amyotrophic-Lateral- Sclerosis Mice Céline Desseille,Séverine Deforges,Olivier Biondi,Léo Houdebine,Domenico D’amicoet al. Frontiers in Molecular Neuroscience, 2017, 10, ⟨10.3389/fnmol.2017.00332⟩ Article dans une revue hal-03684756v1
Specific Physical Exercise Improves Energetic Metabolism in the Skeletal Muscle of Amyotrophic-Lateral- Sclerosis Mice Céline Desseille,Séverine Deforges,Olivier Biondi,Léo Houdebine,Domenico D’amicoet al. Frontiers in Molecular Neuroscience, 2017, 10, ⟨10.3389/fnmol.2017.00332⟩ Article dans une revue hal-04518582v1
Long‐term exercise‐specific neuroprotection in spinal muscular atrophy‐like mice Farah Chali,Céline Desseille,Léo Houdebine,Evelyne Benoit,Thaïs Rouquetet al. The Journal of Physiology, 2016, 594 (7), pp.1931-1952. ⟨10.1113/JP271361⟩ Article dans une revue hal-04518586v1
Long-term exercise-specific neuroprotection in spinal muscular atrophy-like mice. Farah Chali,Céline Desseille,Léo Houdebine,Evelyne Benoit,Thaïs Rouquetet al. The Journal of Physiology, 2016, 594 (7), pp.1931-52. ⟨10.1113/JP271361⟩ Article dans une revue hal-01306145v1
IGF-1R Reduction Triggers Neuroprotective Signaling Pathways in Spinal Muscular Atrophy Mice O. Biondi,J. Branchu,A. Ben Salah,L. Houdebine,L. Bertinet al. Journal of Neuroscience, 2015, 35 (34), pp.12063-12079. ⟨10.1523/JNEUROSCI.0608-15.2015⟩ Article dans une revue hal-05316729v1
Dual Effects of Exercise in Dysferlinopathy Olivier Biondi,Marie Villemeur,Alice Marchand,Fabrice Chrétien,Nathalie Bourget al. American Journal of Pathology, 2013, 182 (6), pp.2298-2309. ⟨10.1016/j.ajpath.2013.02.045⟩ Article dans une revue hal-02338049v1
Exercise-induced activation of NMDA receptor promotes motor unit development and survival in a type 2 spinal muscular atrophy model mouse. Olivier Biondi,Clément Grondard,Sylvie Lécolle,Séverine Deforges,Claude Parisetet al. Journal of Neuroscience, 2008, 28 (4), pp.953-62. ⟨10.1523/JNEUROSCI.3237-07.2008⟩ Article dans une revue hal-00306035v1
Exercise-induced modulation of calcineurin activity parallels the time course of myofibre transitions. Clément Grondard,Olivier Biondi,Claude Pariset,Philippe Lopes,Séverine Deforgeset al. Journal of Cellular Physiology, 2008, 214 (1), pp.126-35. ⟨10.1002/jcp.21168⟩ Article dans une revue istex hal-00306044v1

Communication dans un congrès (9)

Le métabolisme musculaire comme déterminant de l’orientation physiothérapeutique dans le diabète de type 2 Olivier Biondi Thérapies innovantes et combinatoires #2 - "Innovation thérapeutique : Quels enjeux pour le développement des thérapies combinatoires ?", Université d'Evry; Genopole, Jun 2023, Evry, France Communication dans un congrès hal-04495968v1
Synergistic beneficial effects of BIO101 in combination with antisense oligonucleotide therapy in severe SMA-like mice Cynthia Bezier,Parvin Nazari Hashemi,Steve Cottin,René Lafont,Stanislas Veilletet al. 3èmes International Scientific Congress on SMA, SMA Europe, Oct 2022, Barcelone (ES), Spain Communication dans un congrès hal-04496200v1
Combination of antisense oligonucleotide therapy with BIO101 demonstrates synergistic beneficial effects in severe SMA-like mice Cynthia Bezier,Parvin Nazari Hashemi,Steve Cottin,René Lafont,Stanislas Veilletet al. 17th International Congress on Neuromuscular Disease, Jul 2022, Bruxelles (BEL), Belgium Communication dans un congrès hal-04496142v1
Combination of BIO101 with antisense oligonucleotide therapy demonstrates synergistic beneficial effects in severe SMA-like mice Cynthia Bezier,Parvin Nazari Hashemi,Steve Cottin,René Lafont,Stanislas Veilletet al. Myology 2022, Sep 2022, Nice, France Communication dans un congrès hal-04496181v1
Combination of antisense oligonucleotide therapy with BIO101 demonstrates synergistic beneficial effects in severe SMA-like mice Cynthia Bezier,Parvin Nazari Hashemi,Steve Cottin,René Lafont,Stanislas Veilletet al. Annual SMA research & Clinical Care Meeting, Jul 2022, Anaheim (CA), United States Communication dans un congrès hal-04496110v1
Combinatory therapeutic innovation for Spinal Muscular Atrophy Olivier Biondi Innovative, combinatory therapies for neuromuscular diseases, Genopole; Université d'Evry, May 2022, Evry, France Communication dans un congrès hal-04495948v1
Sarconeos (API BIO101) improves outcomes in a mouse model of severe spinal muscular atrophy Cynthia Bezier,Pierre Dilda,René Lafont,Stanislas Veillet,Frédéric Charbonnieret al. 18èmes Journées de la Société Française de Myologie, SFM, Nov 2021, Saint-Etienne (FR), France Communication dans un congrès hal-04496219v1
L'intensité de l'effort, un élément clef des effets de l'exercice dans la SMA ? Olivier Biondi 33èmes Entretiens Annuels de la Fondation Garches, Fondation Garches, Nov 2021, Boulogne-Billancourt, France Communication dans un congrès hal-04495959v1
Regular exercise prolongs survival in a type 2 SMA model mouse C. Grondard,Olivier Biondi,Claude Pariset,Hung Li,C.-L. Gallienet al. 10th International Spinal Mucular Atrophy research Group Meeting, 10,11,12 juin 2006 Montréal, Canada, 2006, Canada Communication dans un congrès hal-00091129v1

Poster de conférence (3)

Exercise-specific effects on the motor performance, glycemia regulation and muscle histology of a mouse model of limb-girdle muscular dystrophy r1 (calpainopathy) Tiphaine Mignot,Sullise Destinval,Malek Kammoun,Mégane Erblang,Yann Simon Gallotet al. 20èmes journées de la Société Française de Myologie, Nov 2023, La Baule (France), France. Poster de conférence hal-04496479v1
Exercise-specific effects on the motor performance, glycemia regulation and muscle histology of a mouse model of limb-girdle muscular dystrophy r1 (calpainopathy) Tiphaine Mignot,Sullise Destinval,Malek Kammoun,Mégane Erblang,Yann Simon Gallotet al. 28th annual congress of European College of Sport Science, Jul 2023, Paris, France. Poster de conférence hal-04496489v1
In vivo effects of Sarconeos (API BIO101) on a mouse model of severe spinal muscular atrophy Cynthia Bezier,Pierre Dilda,René Lafont,Stanislas Veillet,Frédéric Charbonnieret al. World Muscle Society 2021 Virtual Congress, Sep 2021, Paris, France. Poster de conférence hal-04496236v1

Brevet (2)

Phytoecdysones and the derivatives thereof for use in the treatment of neuromuscular diseases Olivier Biondi,Mathilde Latil,Pierre Dilda,René Lafont,Stanislas Veilletet al. France, Patent n° : EP3937948A1. 2022 Brevet hal-04496584v1
ERK inhibitors for use in treating spinal muscular atrophy Frédéric Charbonnier,Olivier Biondi France, Patent n° : 61/489,721. 2011 Brevet hal-04496509v1