Olivier Christophe

Publications

Article dans une revue (43)

Factor VIII restores bone parameters and modulates muscle proteo-metabolome in Factor VIII knockout male mice Antoine Babuty,Javier Muñoz-Garcia,Olivier Christophe,Laurie Fradet,Manon Taupinet al. Bone Research, inPress Article dans une revue hal-05319155v1
Alternative AAV gene therapy for hemophilia A using expression of Bi8, a novel single-chain FVIII-mimetic antibody Vincent Muczynski,Olivier Christophe,Lewis Tanner,Charlotte Vayssiere,Alice Guérinet al. Blood, 2025, ⟨10.1182/blood.2024027709⟩ Article dans une revue hal-05299843v1
Clinical, Phenotypic and Genotypic Characteristics of Von Willebrand Disease in Afro‐Caribbeans: Results From a Study in Martinique Island, French West Indies Marie‐daniéla Dubois,Olivier Nicolas Pierre-Louis,Serge Pierre-Louis,Pierre Boisseau,Cécile Deniset al. Haemophilia, 2025, 31 (3), pp.458-476. ⟨10.1111/hae.70003⟩ Article dans une revue hal-05306019v1
A bispecific nanobody for the treatment of von Willebrand disease type 1 Ivan Peyron,Caterina Casari,Geneviève Mccluskey,Stéphanie Roullet,Vincent Licariet al. Blood, 2025, ⟨10.1182/blood.2025029401⟩ Article dans une revue hal-05263486v1
A fully humanized von Willebrand disease type 1 mouse model as unique platform to investigate novel therapeutic options Geneviève Mccluskey,Marco Heestermans,Ivan Peyron,Eloise Pascal,Marie Clavelet al. Haematologica, In press, ⟨10.3324/haematol.2024.286076⟩ Article dans une revue (data paper) hal-04871911v1
Von Willebrand factor: how unique structural adaptations support and coordinate its complex function Peter J. Lenting,Cécile Denis,Olivier Christophe Blood, 2024, 144 (21), pp.2174-2184. ⟨10.1182/blood.2023023277⟩ Article dans une revue hal-04817254v1
Differences in venous clot structures between hemophilic mice treated with emicizumab versus factor VIII or factor VIIIFc Thibaud Sefiane,Hortense Maynadié,Carmen Escurola Ettingshausen,Vincent Muczynski,Xavier Heiligensteinet al. Haematologica, 2024, ⟨10.3324/haematol.2023.284142⟩ Article dans une revue hal-04449388v1
Thrombin generation on vascular cells in the presence of factor VIII and/or emicizumab Sénadé Atsou,Célia Schellenberg,Jeremy Lagrange,Patrick Lacolley,Peter Lentinget al. Journal of Thrombosis and Haemostasis, 2024, 22 (1), pp.112-125. ⟨10.1016/j.jtha.2023.09.017⟩ Article dans une revue hal-04449373v1
Binding of therapeutic Fc-fused factor VIII to the neonatal Fc receptor at neutral pH associates with poor half-life extension Alejandra Reyes-Ruiz,Sandrine Delignat,Aishwarya Sudam Bhale,Victoria Daventure,Robin Lacombeet al. Haematologica, 2024, 110, pp.1523-1535. ⟨10.3324/haematol.2024.286536⟩ Article dans une revue hal-05361041v1
Fitusiran reduces bleeding in factor X–deficient mice Sebastien Verhenne,Geneviève Mccluskey,Hortense Maynadié,Frédéric Adam,Caterina Casariet al. Blood, 2024, 144 (2), pp.227-236. ⟨10.1182/blood.2023023404⟩ Article dans une revue hal-04654300v1
Imlifidase, a new option to optimize the management of patients with hemophilia A on emicizumab Melissa Bou-Jaoudeh,Angelina Mimoun,Sandrine Delignat,Ivan Peyron,Ladislas Capdevilaet al. Journal of Thrombosis and Haemostasis, 2023, 21 (10), pp.2776-2783. ⟨10.1016/j.jtha.2023.06.038⟩ Article dans une revue hal-04217783v1
A nanobody against the VWF A3 domain detects ADAMTS13-induced proteolysis in congenital and acquired VWD Claire Kizlik-Masson,Ivan Peyron,Stéphane Gangnard,Gaelle Le Goff,Solen Lenoiret al. Blood, 2023, 141 (12), pp.1457-1468. ⟨10.1182/blood.2022017569⟩ Article dans une revue inserm-04258451v1
Angiopoietin-2 binds to multiple interactive sites within von Willebrand factor Alexis Texier,Peter Lenting,Cécile Denis,Stéphanie Roullet,Olivier Christophe Research and Practice in Thrombosis and Haemostasis, 2023, HITH, 7 (7), pp.102204. ⟨10.1016/j.rpth.2023.102204⟩ Article dans une revue (data paper) hal-04449394v1
Transplacental delivery of therapeutic proteins by engineered IgG: a step towards perinatal replacement therapy Angelina Mimoun,Melissa Bou Jaoudeh,Sandrine Delignat,Victoria Daventure,Alejandra Reyes Ruizet al. Journal of Thrombosis and Haemostasis, In press, ⟨10.1016/j.jtha.2023.05.021⟩ Article dans une revue hal-04117814v1
Toll-like receptor 4 and macrophage scavenger receptor 1 crosstalk regulates phagocytosis of a fungal pathogen Chinaemerem Onyishi,Guillaume Desanti,Alex Wilkinson,Samuel Lara-Reyna,Eva-Maria Frickelet al. Nature Communications, 2023, 14 (1), pp.4895. ⟨10.1038/s41467-023-40635-w⟩ Article dans une revue hal-04449439v1
Over‐expression of Dyrk1A affects bleeding by modulating plasma fibronectin and fibrinogen level in mice Guillaume Postic,Jean Solarz,Cécile Loubière,Janany Kandiah,Jaysen Sawmynadenet al. Journal of Cellular and Molecular Medicine, 2023, 27 (15), pp.2228-2238. ⟨10.1111/jcmm.17817⟩ Article dans une revue hal-04294741v1
Over‐expression of Dyrk1A affects bleeding by modulating plasma fibronectin and fibrinogen level in mice Guillaume Postic,Jean Solarz,Cécile Loubière,Janany Kandiah,Jaysen Sawmynadenet al. Journal of Cellular and Molecular Medicine, 2023, 27 (15), pp.228-2238. ⟨10.1111/jcmm.17817⟩ Article dans une revue anses-04164790v1
Development of a dual hybrid AAV vector for endothelial-targeted expression of von Willebrand factor Elena Barbon,Charlotte Kawecki,Solenne Marmier,Aboud Sakkal,Fanny Collaudet al. Gene Therapy, 2023, 30 (3-4), pp.245-254. ⟨10.1038/s41434-020-00218-6⟩ Article dans une revue hal-04455812v1
Efficacy of platelet-inspired hemostatic nanoparticles on bleeding in Von Willebrand disease murine models Stéphanie Roullet,Norman Luc,Julie Rayes,Jean Solarz,Dante Disharoonet al. Blood, 2023, 141 (23), pp.2891-2900. ⟨10.1182/blood.2022018956⟩ Article dans une revue inserm-04066466v1
In vitro recovery of FIX clotting activity as a marker of highly functional hepatocytes in a hemophilia B iPSC model Eléanor Luce,Clara Steichen,Mickaël Allouche,Antonietta Messina,Jean-Marie Heslanet al. Hepatology, 2022, 75 (4), pp.866-880. ⟨10.1002/hep.32211⟩ Article dans une revue inserm-04251849v1
Antithrombotic potential of a single‐domain antibody enhancing the activated protein C‐cofactor activity of protein S Josepha Sedzro,Frédéric Adam,Claire Auditeau,Elsa Bianchini,Allan de Carvalhoet al. Journal of Thrombosis and Haemostasis, 2022, 20 (7), pp.1653-1664. ⟨10.1111/jth.15736⟩ Article dans une revue inserm-04455219v1
Identification of von Willebrand factor D4 domain mutations in patients of Afro‐Caribbean descent: In vitro characterization Marie‐daniéla Dubois,Ivan Peyron,Olivier‐nicolas Pierre-Louis,Serge Pierre-Louis,Johalène Raboutet al. Research and Practice in Thrombosis and Haemostasis, 2022, 6 (4), pp.e12737. ⟨10.1002/rth2.12737⟩ Article dans une revue hal-05306074v1
Development of a dual hybrid AAV vector for endothelial-targeted expression of von Willebrand factor Elena Barbon,Charlotte Kawecki,Solenne Marmier,Aboud Sakkal,Fanny Collaudet al. Gene Therapy, 2021, 30 (3-4), pp.245-254. ⟨10.1038/s41434-020-00218-6⟩ Article dans une revue (data paper) hal-04324328v1
A Combination of Two Variants p. (Val510 =) and p. (Pro2145Thrfs * 5), Responsible for von Willebrand Disease Type 3 in a Caribbean Patient Marie Daniela Dubois,Serge Pierre-Louis,Johalène Rabout,Cécile Denis,Olivier Christopheet al. TH Open : Companion Journal To Thrombosis and Haemostasis, 2020, 04 (04), pp.e318-e321. ⟨10.1055/s-0040-1718703⟩ Article dans une revue hal-05320384v1
Camelid‐derived single‐chain antibodies in hemostasis: Mechanistic, diagnostic, and therapeutic applications Ivan Peyron,Claire Kizlik-Masson,Marie-Daniéla Dubois,Sénadé Atsou,Stephen Ferrièreet al. Research and Practice in Thrombosis and Haemostasis, 2020, 4 (7), pp.1087-1100. ⟨10.1002/rth2.12420⟩ Article dans une revue hal-05320380v1
A Combination of Two Variants p. (Val510 =) and p. (Pro2145Thrfs * 5), Responsible for von Willebrand Disease Type 3 in a Caribbean Patient Marie Daniela Dubois,Serge Pierre-Louis,Johalène Rabout,Cécile Denis,Olivier Christopheet al. TH Open : Companion Journal To Thrombosis and Haemostasis, 2020, 04 (04), pp.e318-e321. ⟨10.1055/s-0040-1718703⟩ Article dans une revue hal-04683162v1
Camelid‐derived single‐chain antibodies in hemostasis: Mechanistic, diagnostic, and therapeutic applications Ivan Peyron,Claire Kizlik‐masson,Marie‐daniéla Dubois,Sénadé Atsou,Stephen Ferrièreet al. Research and Practice in Thrombosis and Haemostasis, 2020, 4 (7), pp.1087-1110. ⟨10.1002/rth2.12420⟩ Article dans une revue hal-03116405v1
A Combination of Two Variants p. (Val510 =) and p. (Pro2145Thrfs * 5), Responsible for von Willebrand Disease Type 3 in a Caribbean Patient Marie Daniela Dubois,Serge Pierre-Louis,Johalène Rabout,Cécile Denis,Olivier Christopheet al. TH Open : Companion Journal To Thrombosis and Haemostasis, 2020, 04 (04), pp.e318-e321. ⟨10.1055/s-0040-1718703⟩ Article dans une revue hal-05306098v1
A Combination of Two Variants p. (Val510 =) and p. (Pro2145Thrfs * 5), Responsible for von Willebrand Disease Type 3 in a Caribbean Patient Marie Daniela Dubois,Marie Daniela Dubois,Serge Pierre-Louis,Johalène Rabout,Cécile Deniset al. TH Open, 2020, 04 (04), pp.e318-e321. ⟨10.1055/s-0040-1718703⟩ Article dans une revue hal-03121861v1
A single‐domain antibody that blocks factor VIIa activity in the absence but not presence of tissue factor Stephen Ferrière,Charlotte Kawecki,Jean‐françois Ottavi,Cécile Denis,Alexandre Kauskotet al. Journal of Thrombosis and Haemostasis, 2019, 17 (12), pp.2035-2046. ⟨10.1111/jth.14615⟩ Article dans une revue hal-04456634v1
Correction of bleeding in experimental severe hemophilia A by systemic delivery of factor VIII- encoding mRNA Jules Russick,Sandrine Delignat,Peter Milanov,Olivier D. Christophe,Gábor Boroset al. Haematologica, 2019, 105 (4), pp.1129-1137. ⟨10.3324/haematol.2018.210583⟩ Article dans une revue hal-02328193v1
Macrophage scavenger receptor SR-AI contributes to the clearance of von Willebrand factor Nikolett Wohner,Vincent Muczynski,Amel Mohamadi,Paulette Legendre,Valérie Proulleet al. Haematologica, 2018, 103 (4), pp.728-737. ⟨10.3324/haematol.2017.175216⟩ Article dans une revue hal-04456818v1
Antigen-selective modulation of AAV immunogenicity with tolerogenic rapamycin nanoparticles enables successful vector re-administration Amine Meliani,Florence Boisgerault,Romain Hardet,Solenne Marmier,Fanny Collaudet al. Nature Communications, 2018, 9 (1), pp.4098. ⟨10.1038/s41467-018-06621-3⟩ Article dans une revue hal-04495633v1
Antigen-selective modulation of AAV immunogenicity with tolerogenic rapamycin nanoparticles enables successful vector re-administration Amine Meliani,Florence Boisgerault,Romain Hardet,Solenne Marmier,Fanny Collaudet al. Nature Communications, 2018, 9 (1), pp.4098. ⟨10.1038/s41467-018-06621-3⟩ Article dans une revue hal-04324439v1
A factor VIII–nanobody fusion protein forming an ultrastable complex with VWF: effect on clearance and antibody formation Vincent Muczynski,Caterina Casari,François Moreau,Gabriel Ayme,Charlotte Kaweckiet al. Blood, 2018, 132 (11), pp.1193-1197. ⟨10.1182/blood-2018-01-829523⟩ Article dans une revue hal-03209466v1
Macrophage scavenger receptor SR-AI contributes to the clearance of von Willebrand factor Nikolett Wohner,Vincent Muczynski,Amel Mohamadi,Paulette Legendre,Valérie Proulleet al. Haematologica, 2018, 103 (4), pp.728-737. ⟨10.3324/haematol.2017.175216⟩ Article dans une revue pasteur-03209471v1
Protein kinase C signaling dysfunction in von Willebrand disease (p.V1316M) type 2B platelets Caterina Casari,David Paul,Sophie Susen,Cécile Lavenu-Bombled,Annie Harrocheet al. Blood Advances, 2018, 2 (12), pp.1417-1428. ⟨10.1182/bloodadvances.2017014290⟩ Article dans une revue hal-04376230v1
A factor VIII–nanobody fusion protein forming an ultrastable complex with VWF: effect on clearance and antibody formation Vincent Muczynski,Caterina Casari,François Moreau,Gabriel Aymé,Charlotte Kaweckiet al. Blood, 2018, 132 (11), pp.1193-1197. ⟨10.1182/blood-2018-01-829523⟩ Article dans une revue (data paper) hal-04456589v1
Complex formation with pentraxin-2 regulates factor X plasma levels and macrophage interactions Vincent Muczynski,Gabriel Aymé,Véronique Regnault,Marc Vasse,Delphine Borgelet al. Blood, 2017, 129 (17), pp.2443-2454. ⟨10.1182/blood-2016-06-724351⟩ Article dans une revue hal-03567147v1
Enhanced liver gene transfer and evasion of preexisting humoral immunity with exosome-enveloped AAV vectors Amine Meliani,Florence Boisgerault,Zachary Fitzpatrick,Solenne Marmier,Christian Leborgneet al. Blood Advances, 2017, 1 (23), pp.2019-2031. ⟨10.1182/bloodadvances.2017010181⟩ Article dans une revue hal-04324460v1
A Novel Single-Domain Antibody Against von Willebrand Factor A1 Domain Resolves Leukocyte Recruitment and Vascular Leakage During Inflammation—Brief Report Gabriel Ayme,Frédéric Adam,Paulette Legendre,Amine Bazaa,Valérie Proulleet al. Arteriosclerosis, Thrombosis, and Vascular Biology, 2017, 37 (9), pp.1736-1740. ⟨10.1161/ATVBAHA.117.309319⟩ Article dans une revue pasteur-03209478v1
Biological outcome and mapping of total factor cascades in response to HIF induction during regenerative angiogenesis Abdel-Majid Khatib,Rachid Lahlil,Martin Hagedorn,Claudine Delomenie,Olivier Christopheet al. Oncotarget, 2016, 7 (11), pp.12102-12120. ⟨10.18632/oncotarget.7728⟩ Article dans une revue hal-03519971v1
LIM kinase/cofilin dysregulation promotes macrothrombocytopenia in severe von Willebrand disease-type 2B Alexandre Kauskot,Sonia Poirault-Chassac,Frédéric Adam,Vincent Muczynski,Gabriel Aymeet al. JCI Insight, 2016, 1 (16), pp.e88643. ⟨10.1172/jci.insight.88643⟩ Article dans une revue hal-03209475v1

Communication dans un congrès (19)

Fitusiran displays efficient pro-hemostatic activity in a mouse model of inducible factor X-deficiency Genevieve Mccluskey,Sebastien Verhenne,Hortense Maynadié,Cécile Denis,Olivier Christopheet al. World Federation of Hemophilia, World Federation of Hemophilia, Apr 2024, Madrid, Spain Communication dans un congrès hal-04654270v1
Fitusiran-treatment modulates the ratio between alpha- and beta-antithrombin isoforms Geneviève Mccluskey,Hortense Maynadié,Caterina Casari,Delphine Borgel,Laurent Frenzelet al. Congrès Français d'Hémostase, Société Française de Thrombose et d'Hémostase, Sep 2024, Lille, France Communication dans un congrès hal-04701035v1
L'angiopoïétine-2 se lie à de multiples sites interactifs au sein du facteur von Willebrand Alexis Texier,Peter J. Lenting,Cécile Denis,Stéphanie Roullet,Olivier Christophe 44e congrès annuel de la Société Française d’Hématologie, Société Française d’Hématologie, Mar 2024, Paris, France. p 327, abstract 18-03 Communication dans un congrès hal-04654288v1
A consistent in vivo factor VIII-equivalence is unlikely to exist for non-factor therapies Hortense Maynadié,Thibaud Sefiane,Genevieve Mccluskey,Marie Clavel,Ivan Peyronet al. Congrès Français d'Hémostase, Société Française de Thrombose et d'Hémostase, Sep 2024, Lille, France Communication dans un congrès hal-04701045v1
L'angiopoïétine-2 se lie à de multiples sites interactifs au sein du facteur von Willebrand Alexis Texier,Peter J. Lenting,Cécile Denis,Stéphanie Roullet,Olivier Christophe 44ème congrès de la Société Française d'Hématologie, Société Française d'Hématologie, Mar 2024, Paris, France. pp.P327, Abstract 18-03 Communication dans un congrès inserm-04541054v1
A single-domain antibody enhancing protein S activity reduces vaso-occlusion in two murine models of sickle cell disease Claire Auditeau,Thiago Maciel,Josepha Sedzro,Camille Roussel,Aurélie Fricot-Monsinjonet al. European Congress on Thrombosis and Haemostasis, Sep 2023, Valence (Espagne), Spain Communication dans un congrès hal-04501174v1
Llama-derived single-domain antibodies blocking tissue factor pathway inhibitor and increasing thrombin generation in FVIII- and FX-deficient plasma Francois Saller,Ivan Peyron,Andrea Ruty,Saenjamsai P,Claire Auditeauet al. European Congress on Thrombosis and Haemostasis, Sep 2023, Valence (Espagne), Spain Communication dans un congrès hal-04501177v1
A FVIII-Mimetic Bispecific Antibody with an Embedded Self-Regulation Mechanism Reduces the Risk of Prothrombotic Events for the Treatment of Haemophilia a Vincent Muczynski,Angel Smith,Thibaud Sefiane,Olivier Christophe,Peter J. Lentinget al. ASH abstracts, Nov 2022, San Diego (CA), United States. pp.677-678, ⟨10.1182/blood-2022-169482⟩ Communication dans un congrès hal-04501469v1
Transplacental Delivery of Maternal FVIII for Induction of FVIII-specific Immune Tolerance Angelina Mimoun,Melissa Bou Jaoudeh,Ivan Peyron,Victoria Daventure,Sandrine Delignatet al. Hybrid Congress of the International Society on Thrombosis and Haemostasis, International Society on Thrombosis and Haemostasis, Jul 2021, Philadelphia (Pennsylvania), United States. pp.Abstract OC 14.1 Communication dans un congrès hal-04501088v1
Antithrombotic Potential of a Single-domain Antibody Enhancing the Anticoagulant Activity of Protein S Josepha Sedzro,Frédéric Adam,Allan De Carvalho,Elsa P Bianchini,Ivan Peyronet al. Hybrid Congress of the International Society on Thrombosis and Haemostasis, International Society on Thrombosis and Haemostasis, Jul 2021, Philadelphia (Pennsylvania), United States. pp.Abstract OC 60.2 Communication dans un congrès hal-04501112v1
Caractérisation d’une nanobody qui potentialize l’activité cofacteur de la protéine C active de la protéine S Sedzro Jc,Francois Saller,Frédéric Adam,De Carvalho,Sophie Gandrilleet al. 40ème congrès de la Société Française d’Hématologie, Société Française d’Hématologie, Sep 2020, Paris, France. pp.Page 39, Abstract 04-01 Communication dans un congrès hal-04501074v1
p.(Pro2145Thrfs*5) et p.(Cys2216Phefs*9), deux Nouvelles mutations identifiées dans le domaine D4 du facteur von Willebrand chez des patientes d’origine afro-caribéenne Marie Daniela Dubois,Serge Pierre-Louis,Johalène Rabout,Cécile Denis,Olivier Christopheet al. 40ème congrès de la Société Française d’Hématologie, Société Française d’Hématologie, Sep 2020, Paris, France. p 50, Abstract 05-07 Communication dans un congrès hal-04501081v1
Von Willebrand factor induces human vascular smooth muscle cells proliferation through low density lipoprotein-related receptor 4 and alphavbeta3 integrin Morel Worou,Melusine Didelot,Vincent Muczynski,Raoul A,Paulette Legendreet al. XXVIIth Congress of the International Society on Thrombosis and Haemostasis, International Society on Thrombosis and Haemostasis, Jul 2019, Melbourne (AUS), Australia Communication dans un congrès hal-04498513v1
A inducible mouse model of Factor X deficiency to test novel FX therapeutics Sebastien Verhenne,Loubiere C,Cécile Denis,Peter J. Lenting,Olivier Christophe XXVIIth Congress of the International Society on Thrombosis and Haemostasis, International Society on Thrombosis and Haemostasis, Jul 2019, Melbourne (AUS), Australia. pp.Abstract OC 28.4 Communication dans un congrès hal-04499851v1
Targeting Protease Nexin-1, a natural anticoagulant to control bleeding in hemophilia A Karen Aymonnier,Charlotte Kawecki,Laurence Venisse,Emmanuelle de Raucourt,Olivier Christopheet al. XXVIIth Congress of the International Society on Thrombosis and Haemostasis, International Society on Thrombosis and Haemostasis, Jul 2019, Melbourne (AUS), Australia. pp.Abstract OC 75.3 Communication dans un congrès hal-04498448v1
Développement d’un modèle de souris avec un déficit inductible en facteur X Sebastien Verhenne,Loubière Cécile,Elena Barbon,F Mingozzi,Cécile Deniset al. 39th Congress of the Société Française d’Hématologie, Société Française d’Hématologie, Mar 2019, Paris, France. pp.Abstract 12-29 Communication dans un congrès hal-04498403v1
La Protéase Nexine-1, un inhibiteur physiologique de la thrombine, cible potentielle dans le traitement de l’hémophilie. Karen Aymonnier,Charlotte Kawecki,Laurence Venisse,Emmanuelle de Raucourt,Olivier Christopheet al. 38th Congress of the Société Française d’Hématologie, Société Française d’Hématologie, Mar 2018, PARIS, France. p 133, Abstract 12-59 Communication dans un congrès hal-04457483v1
The potential use of nanobodies delivered via AAV vectors in the treatment of hemophilia Elena Barbon,Gabriel Ayme,Amel Mohamadi,Cécile Denis,Olivier Christopheet al. 21st Annual Meeting of the American Society of Gene and Cell Therapy, American Society of Gene and Cell Therapy, May 2018, CHICAGO, United States Communication dans un congrès hal-04457494v1
Targeting Protease Nexin-1, a natural anticoagulant to control bleeding in hemophilia A Karen Aymonnier,Charlotte Kawecki,Laurence Venisse,Emmanuelle de Raucourt,Olivier Christopheet al. 2nd European Congress on Thrombosis and Haemostasis, Oct 2018, Marseille, France Communication dans un congrès hal-04457505v1

Poster de conférence (4)

Transplacental delivery of maternal factor VIII for induction of immune tolerance to therapeutic factor VIII Angelina Mimoun,Melissa Bou Jaoudeh,Ivan Peyron,Daventure V,Sandrine Delignatet al. Virtual Congress of the International Society on Thrombosis and Haemostasis, Jul 2020, Milan (Virtual), Italy. Res. Pract. Thromb. Haemost, 4 (Suppl. 1), pp.Abstract PB0177, 2020 Poster de conférence hal-04501045v1
Protein engineering in FLT210, a Potent Next Generation AAV-hFVIII Vector Candidate Tihomir Dodev,Petya Kalcheva,Azadeh Kia,Samantha Correia,Caterina Casariet al. Protein Engineering Summit PEGS, Aug 2020, Boston - online, United States Poster de conférence hal-04461544v1
Development of single domain antibodies targeting protease nexin-1 as a strategy for hemophilia treatment Charlotte Kawecki,Karen Aymonnier,Laurence Venisse,Véronique Arocas,Olivier Christopheet al. XXVIIth Congress of the International Society on Thrombosis and Haemostasis, Jul 2019, Melbourne (AUS), Australia. Res. Pract. Thromb. Haemost, 3 (Suppl. 1), pp.Abstract PB0316, 2019 Poster de conférence hal-04499858v1
Modulation of the platelet count by Romiplostim and inhibitors of LIM kinase in genetically-engineered von Willebrand disease type 2B mice: in vivo evaluation of haemostatic efficiency. Mathilde Cheptou,Frédéric Adam,Olivier Christophe,Peter Lenting,Cécile Deniset al. ECTH, 2018, Oct 2018, Marseille, France Poster de conférence hal-04455308v1

Proceedings/Recueil des communications (2)

Design and Characterization of FLT210, a Potent Next Generation AAV-hFVIII Vector Candidate Azadeh Kia,Fabrizio Comper,Samantha Correia,Caterina Casari,Segen Negashet al. 61 ASH Annual Meeting, Blood, 134 (Supplement_1), pp.4638-4638, 2019, ⟨10.1182/blood-2019-128490⟩ Proceedings/Recueil des communications hal-04461585v1
Thrombin-mediated activation of factor VIII is insufficient to produce all necessary cofactor activity in vivo Charlotte Kawecki,Ivan Peyron,Amine Bazaa,Vincent Muczynski,Stephen Ferrièreet al. Congress of the International Society of Thrombosis and Haemostasis, Research and Practice in Thrombosis and Haemostasis, 3, pp.1-891, 2019, ⟨10.1002/rth2.12229⟩ Proceedings/Recueil des communications hal-04461945v1