Pascal Pigeon

Identifiants chercheurs

IdHAL :

pascal-pigeon

ORCID :

0000-0001-5374-5346

IdRef :

196560039

ResearcherID :

F-9758-2014

Publications

Article dans une revue (98)

Self-assemblies from prodrugs composed of antimicrobial peptides: a revolution in local lung cancer treatment, with microbiota as a main actor Abdallah Ladaycia,Laurent Lemaire,Hélène Pailhoriès,Nolwenn Lautram,Florence Franconiet al. Drug Delivery and Translational Research, 2026, Online ahead of print. ⟨10.1007/s13346-025-02037-x⟩ Article dans une revue hal-05448769v1
Self-assemblies of cell-penetrating peptides and ferrocifens: design and biological evaluation of an innovative platform for lung cancer treatment Léna Guyon,Abdallah Ladaycia,Agnese Bosio,Laurent Lemaire,Florence Franconiet al. Nanoscale, 2025, 17 (15), pp.9232-9244. ⟨10.1039/D5NR00643K⟩ Article dans une revue hal-04996247v1
An Alternative Method for Preparing Methyl 2-Ferrocenyl-2-oxo-acetate Pascal Pigeon,Hugo Hapel Molbank, 2025, Organic Synthesis and Biosynthesis, pp.M2009. ⟨10.3390/M2009⟩ Article dans une revue hal-05077274v1
Ethyl 4-Ene-4-ferrocenyl-5,5-bis-(4-hydroxyphenyl)-pentanoate Jérémy Forté,Pascal Pigeon Molbank, 2025, Structure Determination, 2025 (1), pp.M1980. ⟨10.3390/M1980⟩ Article dans une revue hal-04990488v1
How Does Ferrocene Correlate with Ferroptosis? Multiple Approaches to Explore Ferrocene-Appended GPX4 Inhibitors as Anticancer Agents Wei Li,Jing Yu,Jing Wang,Xuejing Fan,Ximing Xuet al. Chemical Science, 2024, 15, pp.10477-10490. ⟨10.1039/D4SC02002B⟩ Article dans une revue hal-04601570v1
Deciphering the Diversified Metabolic Behavior of Hydroxyalkyl Ferrocidiphenols as Anticancer Complexes Hui Wang,Xuejing Fan,Pei-Pei Xie,Shuang Yang,Pascal Pigeonet al. Journal of Medicinal Chemistry, 2024, 67 (2), pp.1209-1224. ⟨10.1021/acs.jmedchem.3c01709⟩ Article dans une revue hal-04369370v1
1,1-Bis(4-hydroxyphenyl)-2-ferrocenylbutane Jérémy Forté,Patrick Herson,Pascal Pigeon Molbank, 2024, Structure Determination, 2024 (4), pp.M1932. ⟨10.3390/M1932⟩ Article dans une revue hal-04824406v1
Physicochemical Characterization of Ferrocifen Lipid Nanocapsules: Customized Drug Delivery Systems Guided by the Molecular Structure Pierre Idlas,Elise Lepeltier,Guillaume Bastiat,Pascal Pigeon,Michael Mcglincheyet al. Langmuir, 2023, 39 (5), pp.1885-1896. ⟨10.1021/acs.langmuir.2c02910⟩ Article dans une revue hal-03955374v1
Unravelling the Role of Uncommon Hydrogen Bonds in Cyclodextrin Ferrociphenol Supramolecular Complexes: A Computational Modelling and Experimental Study Pascal Pigeon,Feten Najlaoui,Michael James Mcglinchey,Juan Sanz García,Gérard Jaouenet al. International Journal of Molecular Sciences, 2023, Special Issue Cyclodextrins: Properties and Applications, 24 (15), pp.12288. ⟨10.3390/ijms241512288⟩ Article dans une revue hal-04176438v1
Ferrocifen stealth LNCs and conventional chemotherapy: A promising combination against multidrug-resistant ovarian adenocarcinoma Pierre Idlas,Abdallah Ladaycia,Fariba Némati,Elise Lepeltier,Pascal Pigeonet al. International Journal of Pharmaceutics, 2022, 626, pp.122164. ⟨10.1016/j.ijpharm.2022.122164⟩ Article dans une revue hal-03774820v1
Synthesis, Electrochemical and Fluorescence Properties of the First Fluorescent Member of the Ferrocifen Family and of its Oxidized Derivatives Charles Fayolle,Pascal Pigeon,Nathalie Fischer-Durand,Michèle Salmain,Olivier O. Buriezet al. Molecules, 2022, 27 (19), pp.6690. ⟨10.3390/molecules27196690⟩ Article dans une revue hal-03807919v1
Diversity-oriented synthesis and bioactivity evaluation of N-substituted ferrocifen compounds as novel antiproliferative agents against TNBC cancer cells Yong Wang,Pascal Pigeon,Wei Li,Jiangkun Yan,Patrick M Dansetteet al. European Journal of Medicinal Chemistry, 2022, 234, pp.114202. ⟨10.1016/j.ejmech.2022.114202⟩ Article dans une revue hal-03599161v1
Inhibition of cathepsin B by ferrocenyl indenes highlights a new pharmacological facet of ferrocifens Juan Sanz Garcia,Marie Gaschard,Isabelle Navizet,Mehdi Sahihi,Siden Topet al. European Journal of Inorganic Chemistry, 2022, 2022 (9), pp.e202101075. ⟨10.1002/ejic.202101075⟩ Article dans une revue hal-03527077v1
Succinimido–Ferrocidiphenol Complexed with Cyclodextrins Inhibits Glioblastoma Tumor Growth In Vitro and In Vivo without Noticeable Adverse Toxicity Feten Najlaoui,Benoît Busser,Germain Sotoing Taïwe,Pascal Pigeon,Nathalie Sturmet al. Molecules, 2022, 27 (14), pp.4651. ⟨10.3390/molecules27144651⟩ Article dans une revue hal-03736856v1
α-Hydroxylactams as Efficient Entries to Diversely Functionalized Ferrociphenols: Synthesis and Antiproliferative Activity Studies Pascal Pigeon,Marie Gaschard,Mohamed Othman,Michèle Salmain,Gérard Jaouen Molecules, 2022, 27 (14), pp.4549. ⟨10.3390/molecules27144549⟩ Article dans une revue hal-03736842v1
Heterogeneity of Response to Iron-Based Metallodrugs in Glioblastoma Is Associated with Differences in Chemical Structures and Driven by FAS Expression Dynamics and Transcriptomic Subtypes Anne Vessieres,Emie Quissac,Nolwenn Lemaire,Agusti Alentorn,Patrycja Domerackaet al. International Journal of Molecular Sciences, 2021, 22 (19), pp.10404. ⟨10.3390/ijms221910404⟩ Article dans une revue hal-03356305v1
Antimicrobial, antitumor and side effects assessment of a newly synthesized tamoxifen analogue Fatma Abdmouleh,Mehdi El Arbi,Hajer Ben Saad,Karim Jellali,Emna E. Ketataet al. Current Topics in Medicinal Chemistry, 2020, 20 (25), pp.2281-2288. ⟨10.2174/1568026620666200819145526⟩ Article dans une revue hal-02921197v1
Importance of Combining Advanced Particle Size Analysis Techniques To Characterize Cell-Penetrating Peptide–Ferrocifen Self-Assemblies Léna Guyon,Elise Lepeltier,Jean-Christophe Gimel,Brice Calvignac,Florence Franconiet al. Journal of Physical Chemistry Letters, 2019, 10 (21), pp.6613-6620. ⟨10.1021/acs.jpclett.9b01493⟩ Article dans une revue hal-02319158v1
Small Structural Differences between Two Ferrocenyl Diphenols Determine Large Discrepancies of Reactivity and Biological Effects Federica Tonolo,Michèle Salmain,Valeria Scalcon,Siden Top,Pascal Pigeonet al. ChemMedChem, 2019, 14 (19), pp.1717-1726. ⟨10.1002/cmdc.201900430⟩ Article dans une revue hal-02282225v1
Atypical lone pair-π interaction with quinone methides in a series of imido-ferrociphenol anticancer drug candidates Yong Wang,Pascal Pigeon,Siden Top,Juan Garcia,Claire Troufflardet al. Angewandte Chemie International Edition, 2019, 58 (25), pp.8421-8425. ⟨10.1002/anie.201902456⟩ Article dans une revue hal-02103918v1
Enhanced and preferential internalization of lipid nanocapsules into human glioblastoma cells: effect of a surface-functionalizing NFL peptide Reatul Karim,Elise Lepeltier,Lucille Esnault,Pascal Pigeon,Laurent Lemaireet al. Nanoscale, 2018, 10, pp.13485-13501. ⟨10.1039/C8NR02132E⟩ Article dans une revue hal-01817763v1
Aryl butenes active against K562 cells and lacking tyrosinase inhibitory activity as new leads in the treatment of leukemia Mehdi El Arbi,Emna E. Ketata,Aref Neifar,Wafa Mihoubi,Girish K. G. K. Guptaet al. Mini-Reviews in Medicinal Chemistry, 2018, 18 (15), pp.1294-1301. ⟨10.2174/1389557517666170208142254⟩ Article dans une revue hal-01479613v1
Anticancer properties of lipid and poly(ε-caprolactone) nanocapsules loaded with ferrocenyl-tamoxifen derivatives Feten Najlaoui,Pascal Pigeon,Sonia Aroui,Mylène Pezet,Lucie Sanceyet al. Journal of Pharmacy and Pharmacology, 2018, 70 (11), pp.1474-1484. ⟨10.1111/jphp.12998⟩ Article dans une revue hal-01861749v1
Selective cytotoxicity of arene tricarbonylchromium towards tumour cell lines Jihene Elloumi-Mseddi,Sami Mnif,Nejmeddine Akacha,Bochra Hakim,Pascal Pigeonet al. Journal of Organometallic Chemistry, 2018, 862, pp.7-12. ⟨10.1016/j.jorganchem.2018.01.036⟩ Article dans une revue hal-01720644v1
A new generation of ferrociphenols leads to a great diversity of reactive metabolites, and exhibits remarkable antiproliferative properties Yong Wang,Patrick M Dansette,Pascal Pigeon,Siden Top,Michael James Mcglincheyet al. Chemical Science, 2018, 9, pp.70-78. ⟨10.1039/C7SC04213B⟩ Article dans une revue hal-01646922v1
A New Series of Succinimido-ferrociphenols and Related Heterocyclic Species Induce Strong Antiproliferative Effects, Especially against Ovarian Cancer Cells Resistant to Cisplatin Pascal Pigeon,Yong Wang,Siden Top,Feten Najlaoui,Maria Concepcion Garcia Alvarezet al. Journal of Medicinal Chemistry, 2017, 60 (20), pp.8358-8368. ⟨10.1021/acs.jmedchem.7b00743⟩ Article dans une revue hal-01611795v1
The inhibition of tyrosinase by some aryl butenes: A desired activity or a side effect to avoid Emna E. Ketata,Aref Neifar,Wafa Mihoubi,Pascal Pigeon,Hicham Gouziet al. Journal of Organometallic Chemistry, 2017, 848, pp.133 - 141. ⟨10.1016/j.jorganchem.2017.07.031⟩ Article dans une revue hal-01611372v1
Synthesis and antiproliferative evaluation of novel hydroxypropyl-ferrociphenol derivatives, resulting from the modification of hydroxyl groups Wang Yong,Pascal Pigeon,Michael J. Mcglinchey,Siden Top,Gérard Jaouen Journal of Organometallic Chemistry, 2017, 829, pp.108-115. ⟨10.1016/j.jorganchem.2016.09.005⟩ Article dans une revue hal-01484511v1
Side-Chain Effects on the 1-(Bis-aryl-methylidene)-[3]ferrocenophane Skeleton: Antiproliferative Activity against TNBC Cancer Cells and Comparison with the Acyclic Ferrocifen Series Meral Gormen,Pascal Pigeon,Yong Wang,Anne Vessières,Siden Topet al. European Journal of Inorganic Chemistry, 2017, Special Issue: The Multifaceted Chemistry of Ferrocene (Cluster Issue), 2017 (2), pp.454-465. ⟨10.1002/ejic.201601088⟩ Article dans une revue hal-01408995v1
Tamoxifen-like metallocifens target the thioredoxin system determining mitochondrial impairment leading to apoptosis in Jurkat cells Valeria Scalcon,Michèle Salmain,Alessandra Folda,Siden Top,Pascal Pigeonet al. Metallomics, 2017, 9 (7), pp.949-959. ⟨10.1039/C7MT00121E⟩ Article dans une revue hal-01611386v1
Ferrocenyl Quinone Methide-Thiol Adducts as New Antiproliferative Agents: Synthesis, Metabolic Formation from Ferrociphenols, and Oxidative Transformation Yong Wang,Marie-Aude Richard,Siden Top,Patrick M. Dansette,Pascal Pigeonet al. Angewandte Chemie, 2016, 55 (35), pp.10431-10434. ⟨10.1002/anie.201603931⟩ Article dans une revue hal-01345781v1
Enzymatic oxidation of ansa-ferrocifen leads to strong and selective thioredoxin reductase inhibition in vitro Valeria Scalcon,Anna Citta,Alessandra Folda,Alberto Bindoli,Michèle Salmainet al. Journal of Inorganic Biochemistry, 2016, 165, pp.146-151. ⟨10.1016/j.jinorgbio.2016.08.005⟩ Article dans une revue hal-01401089v1
Efficacy of a novel ferrocenyl diaryl butene citrate compound as a biocide for preventing healthcare-associated infections Mehdi El Arbi,Karim Jalléli,Fatma Trigui,Pascal Pigeon,Meral Görmenet al. MedChemComm, 2016, 7 (5), pp.948-954. ⟨10.1039/C5MD00568J⟩ Article dans une revue hal-01289145v1
The length of the bridging chain in ansa-metallocenes influences their antiproliferative activity against triple negative breast cancer cells (TNBC) Matthieu Beauperin,Siden Top,Marie-Aude Richard,Damian Plażuk,Pascal Pigeonet al. Dalton Transactions, 2016, 45, pp.13126-13134. ⟨10.1039/C6DT01640E⟩ Article dans une revue hal-01338321v1
Oxidative Metabolism of Ferrocene Analogues of Tamoxifen: Characterization and Antiproliferative Activities of the Metabolites Marie-Aude Richard,Didier Hamels,Pascal Pigeon,Siden Top,Patrick M. Dansetteet al. ChemMedChem, 2015, 10 (6), pp.981-990. ⟨10.1002/cmdc.201500075⟩ Article dans une revue hal-01230370v1
Organometallic Antitumor Compounds: Ferrocifens as Precursors to Quinone Methides Yong Wang,Pascal Pigeon,Siden Top,Michael J. Mcglinchey,Gérard Jaouen Angewandte Chemie International Edition, 2015, 54 (35), pp.10230-10233. ⟨10.1002/anie.201503048⟩ Article dans une revue hal-01230371v1
Phthalimido-ferrocidiphenol cyclodextrin complexes: Characterization and anticancer activity Feten Najlaoui,Pascal Pigeon,Zaineb Abdelkafi,Sebastien Leclerc,Pierrick Durandet al. International Journal of Pharmaceutics, 2015, 491 (1-2), pp.323-334. ⟨10.1016/j.ijpharm.2015.06.043⟩ Article dans une revue hal-01218567v1
Antiplasmodial activity of iron(II) and ruthenium(II) organometallic complexes against Plasmodium falciparum blood parasites Nicolli Bellotti De Souza,Anna Caroline Campos Aguiar,Alane Cabral De Oliveira,Siden Top,Pascal Pigeonet al. Memórias do Instituto Oswaldo Cruz, 2015, 110 (8), pp.981-988. ⟨10.1590/0074-02760150163⟩ Article dans une revue hal-01261304v1
Atypical McMurry Cross-Coupling Reactions Leading to a New Series of Potent Antiproliferative Compounds Bearing the Key [Ferrocenyl-Ene-Phenol] Motif Pascal Pigeon,Meral Goermen,Konrad Kowalski,Helge Mueller-Bunz,Michael J. Mcglincheyet al. Molecules, 2014, 19 (7), pp.10350-10369. ⟨10.3390/molecules190710350⟩ Article dans une revue hal-01230372v1
Molecular Mechanism of Action of 2-Ferrocenyl-1,1-diphenylbut-1-ene on HL-60 Leukemia Cells Alane Cabral De Oliveira,Emanuella Gomes Da Silva,Danilo Damasceno Rocha,Elisabeth A. Hillard,Pascal Pigeonet al. ChemMedChem, 2014, 9 (11), pp.2580-2586. ⟨10.1002/cmdc.201402219⟩ Article dans une revue istex hal-01230375v1
Evidence for Targeting Thioredoxin Reductases with Ferrocenyl Quinone Methides. A Possible Molecular Basis for the Antiproliferative Effect of Hydroxyferrocifens on Cancer Cells Anna Citta,Alessandra Folda,Alberto Bindoli,Pascal Pigeon,Siden Topet al. Journal of Medicinal Chemistry, 2014, 57 (21), pp.8849-8859. ⟨10.1021/jm5013165⟩ Article dans une revue hal-01230376v1
Antibacterial properties and mode of action of new triaryl butene citrate compounds Mehdi El Arbi,Jeremie Theolier,Pascal Pigeon,Karim Jellali,Fatma Triguiet al. European Journal of Medicinal Chemistry, 2014, 76, pp.408-413. ⟨10.1016/j.ejmech.2014.02.037⟩ Article dans une revue istex hal-01230373v1
Oxidative Sequence of a Ruthenocene-Based Anticancer Drug Candidate in a Basic Environment Hui Zhi Shirley Lee,Olivier Buriez,Eric Labbé,Siden Top,Pascal Pigeonet al. Organometallics, 2014, 33 (18), pp.4940-4946. ⟨10.1021/om500225k⟩ Article dans une revue hal-01230374v1
Ferrocifen derivatives that induce senescence in cancer cells: selected examples Celine Bruyere,Veronique Mathieu,Anne Vessières,Pascal Pigeon,Siden Topet al. Journal of Inorganic Biochemistry, 2014, 141, pp.144-151. ⟨10.1016/j.jinorgbio.2014.08.015⟩ Article dans une revue hal-01230377v1
Selection of a suitable disc bioassay for the screening of anti-tumor molecules Fatma Trigui,Pascal Pigeon,Karim Jalleli,Siden Top,Sami Aifaet al. International journal of biomedical science: IJBS, 2013, 9 (4), pp.230--236 Article dans une revue hal-01230383v1
The in vivo performance of ferrocenyl tamoxifen lipid nanocapsules in xenografted triple negative breast cancer Anne-Laure Lainé,Eric Adriaenssens,Anne Vessières,Gérard Jaouen,Cyril Corbetet al. Biomaterials, 2013, 34 (28), pp.6949-6956. ⟨10.1016/j.biomaterials.2013.05.065⟩ Article dans une revue hal-01230382v1
Ferrocenyl flavonoid-induced morphological modifications of endothelial cells and cytotoxicity against B16 murine melanoma cells Jean-Philippe Monserrat,Keshri Nath Tiwari,Lionel Quentin,Pascal Pigeon,Gérard Jaouenet al. Journal of Organometallic Chemistry, 2013, 734 (SI), pp.78-85. ⟨10.1016/j.jorganchem.2012.12.031⟩ Article dans une revue hal-01230380v1
Effect of the amino chain length and the transformation into citric acid salts of aryl-diphenyl-butenes and ferrocenyl-diphenyl-butenes bearing two dimethylaminoalkyl chains on their antimicrobial activities Karim Jellali,Pascal Pigeon,Fatma Trigui,Siden Top,Sami Aifaet al. SpringerPlus, 2013, 2 (1), pp.508. ⟨10.1186/2193-1801-2-508⟩ Article dans une revue hal-01230378v1
Ferrocenyl catechols: synthesis, oxidation chemistry and anti-proliferative effects on MDA-MB-231 breast cancer cells Yong Leng Kelvin Tan,Pascal Pigeon,Siden Top,Eric Labbé,Olivier Buriezet al. Dalton Transactions, 2012, 41 (25), pp.7537-7549. ⟨10.1039/c2dt30700f⟩ Article dans une revue hal-01230385v1
Synthesis and Antiproliferative Effects of [3]Ferrocenophane Transposition Products and Pinacols Obtained from McMurry Cross-Coupling Reactions Meral Görmen,Pascal Pigeon,Elisabeth A. Hillard,Anne Vessières,Michel Huchéet al. Organometallics, 2012, 31 (16), pp.5856-5866. ⟨10.1021/om300382h⟩ Article dans une revue hal-01230386v1
Biological evaluation of twenty-eight ferrocenyl tetrasubstituted olefins: Cancer cell growth inhibition, ROS production and hemolytic activity Alane Cabral De Oliveira,Elisabeth A. Hillard,Pascal Pigeon,Danilo Damasceno Rocha,Felipe A. R. Rodrigueset al. European Journal of Medicinal Chemistry, 2011, 46 (9), pp.3778-3787. ⟨10.1016/j.ejmech.2011.05.043⟩ Article dans une revue istex hal-01230389v1
A new series of ferrocifen derivatives, bearing two aminoalkyl chains, with strong antiproliferative effects on breast cancer cells Pascal Pigeon,Siden Top,Anne Vessières,Michel Huché,Meral Goermenet al. New Journal of Chemistry, 2011, 35 (10), pp.2212-2218. ⟨10.1039/c1nj20192a⟩ Article dans une revue hal-01230387v1
Evaluation of bactericidal and fungicidal activity of ferrocenyl or phenyl derivatives in the diphenyl butene series Mehdi El Arbi,Pascal Pigeon,Siden Top,Ali Rhouma,Sami Aifaet al. Journal of Organometallic Chemistry, 2011, 696 (5), pp.1038-1048. ⟨10.1016/j.jorganchem.2010.09.015⟩ Article dans une revue istex hal-01230388v1
ANTIMICROBIAL EFFECT OF FERROCENYL DIARYL BUTENES AGAINST OLIVE PLANTLET DISEASES M. El Arbi,Pascal Pigeon,A. Chaari Rkhis,Siden Top,A. Rhoumaet al. Journal of Plant Pathology, 2011, 93 (3), pp.651-657 Article dans une revue hal-01230390v1
Facile synthesis and strong antiproliferative activity of disubstituted diphenylmethylidenyl-[3]ferrocenophanes on breast and prostate cancer cell lines Meral Görmen,Pascal Pigeon,Siden Top,Anne Vessières,Marie-Aude Plamontet al. MedChemComm, 2010, 1 (2), pp.149-151. ⟨10.1039/c0md00026d⟩ Article dans une revue istex hal-01230393v1
Synthesis, Cytotoxicity, and COMPARE Analysis of Ferrocene and [3]Ferrocenophane Tetrasubstituted Olefin Derivatives against Human Cancer Cells Meral Goermen,Pascal Pigeon,Siden Top,Elisabeth A. Hillard,Michel Huchéet al. ChemMedChem, 2010, 5 (12), pp.2039-2050. ⟨10.1002/cmdc.201000286⟩ Article dans une revue hal-01230394v1
Antiparasitic and Immunomodulatory Activities of 1,1-bis(4-Hydroxyphenyl)-2-Phenyl-but-1-ene and Its Protected and Free 2-Ferrocenyl Derivatives Milena B. P. Soares,Jose Fernando Oliveira Costa,Matheus Santos De Sa,Ricardo Ribeiro-Dos-Santos,Pascal Pigeonet al. Drug Development Research, 2010, 71 (1, SI), pp.69-75. ⟨10.1002/ddr.20349⟩ Article dans une revue hal-01230392v1
Comparative toxicity of [3]ferrocenophane and ferrocene moieties on breast cancer cells Meral Görmen,Damian Plazuk,Pascal Pigeon,Elisabeth A. Hillard,Marie-Aude Plamontet al. Tetrahedron Letters, 2010, 51 (1), pp.118-120. ⟨10.1016/j.tetlet.2009.10.102⟩ Article dans une revue hal-01230391v1
Synthesis and Structure-Activity Relationships of Ferrocenyl Tamoxifen Derivatives with Modified Side Chains. A. Nguyen,S. Top,Pascal Pigeon,A. Vessieres,E.A. Hillardet al. Chemistry - A European Journal, 2009, 15, pp.684-696. ⟨10.1002/chem.200801108⟩ Article dans une revue hal-00376089v1
Role of aromatic substituents on the antiproliferative effects of diphenyl ferrocenyl butene compounds Ouardia Zekri,Elisabeth A. Hillard,Siden Top,Anne Vessières,Pascal Pigeonet al. Dalton Transactions, 2009, 22, pp.4318-4326. ⟨10.1039/B819812H⟩ Article dans une revue istex hal-00449003v1
Dose effect activity of ferrocifen-loaded lipid nanocapsules on a 9L-glioma model E. Allard,N. T. Huynh,A. Vessières,Pascal Pigeon,G. Jaouenet al. International Journal of Pharmaceutics, 2009, 379 (2), pp.317-323. ⟨10.1016/j.ijpharm.2009.05.031⟩ Article dans une revue hal-01230396v1
A [3]Ferrocenophane polyphenol showing a remarkable antiproliferative activity on breast and prostate cancer cell lines Damian Plazuk,Anne Vessières,Elisabeth A. Hillard,Olivier Buriez,Eric Labbéet al. Journal of Medicinal Chemistry, 2009, 52, pp.4964-4967. ⟨10.1021/jm900297x⟩ Article dans une revue hal-00448988v1
Synthesis, oxidation chemistry and cytotoxicity studies on ferrocene derivatives of diethylstilbestrol Yong Leng Kelvin Tan,Pascal Pigeon,Elisabeth A. Hillard,Siden Top,Marie-Aude Plamontet al. Dalton Transactions, 2009, 48, pp.10871-10881. ⟨10.1039/b913570g⟩ Article dans une revue istex hal-01230395v1
The replacement of a phenol group by an aniline or acetanilide group enhances the cytotoxicity of 2-ferrocenyl-1,1-diphenyl-but-1-ene compounds against breast cancer cells Pascal Pigeon,Siden Top,Ouardia O. Zekri,Elisabeth A. Hillard,Anne A. Vessiereset al. Journal of Organometallic Chemistry, 2009, 694, pp.895-901. ⟨10.1016/j.jorganchem.2008.11.035⟩ Article dans une revue hal-00376093v1
Lipid nanocapsules loaded with an organometallic tamoxifen derivative as a novel drug-carrier system for experimental malignant gliomas. Emilie Allard,Catherine Passirani,Emmanuel Garcion,Pascal Pigeon,Anne Vessièreset al. Journal of Controlled Release, 2008, 130 (2), pp.146-53. ⟨10.1016/j.jconrel.2008.05.027⟩ Article dans une revue inserm-00343557v1
Electrochemical attachment of a conjugated amino-ferrocifen complex onto carbon and metal surfaces Olivier Buriez,Eric Labbé,Pascal Pigeon,Gérard Jaouen,Christian Amatore Journal of electroanalytical chemistry and interfacial electrochemistry, 2008, 619, pp.169-175. ⟨10.1016/j.jelechem.2008.04.012⟩ Article dans une revue hal-01230398v1
Ferrocenyl compounds possessing protected phenol and thiophenol groups: Synthesis, X-ray structure, and in vitro biological effects against breast cancer Julia B. Heilmann,Elisabeth A. Hillard,Marie-Aude Plamont,Pascal Pigeon,Michael Bolteet al. Journal of Organometallic Chemistry, 2008, 693 (8-9), pp.1716-1722. ⟨10.1016/j.jorganchem.2007.12.011⟩ Article dans une revue hal-01230397v1
Nanoparticles loaded with ferrocenyl tamoxifen derivatives for breast cancer treatment. Anh Nguyen,Véronique Marsaud,Céline Bouclier,Siden Top,Anne Vessiereset al. International Journal of Pharmaceutics, 2008, 347 (1-2), pp.128-35. ⟨10.1016/j.ijpharm.2007.06.033⟩ Article dans une revue hal-00180710v1
The influence of phenolic hydroxy substitution on the electron transfer and anti-cancer properties of compounds based on the 2-ferrocenyl-1-phenyl-but-1-ene motif Elisabeth A. Hillard,Pascal Pigeon,Anne Vessières,Christian Amatore,Gérard Jaouen Dalton Transactions, 2007, 43, pp.5073-5081. ⟨10.1039/b705030e⟩ Article dans une revue hal-01230399v1
Organometallic analogues of tamoxifen: Effect of the amino side-chain replacement by a carbonyl ferrocenyl moiety in hydroxytamoxifen Anh Nguyen,Siden Top,Anne Vessières,Pascal Pigeon,Michel Huchéet al. Journal of Organometallic Chemistry, 2007, 692 (6, SI), pp.1219-1225. ⟨10.1016/j.jorganchem.2006.11.016⟩ Article dans une revue hal-01230401v1
Ferrocifens and ferrocifenols as new potential weapons against breast cancer Anh Nguyen,Anne Vessières,Elisabeth A. Hillard,Siden Top,Pascal Pigeonet al. CHIMIA, 2007, 61 (11), pp.716-724. ⟨10.2533/chimia.2007.716⟩ Article dans une revue hal-01230400v1
Organometallic diphenols: The importance of the organometallic moiety on the expression of a cytotoxic effect on breast cancer cells Elisabeth A. Hillard,Anne Vessières,Siden Top,Pascal Pigeon,Konrad Kowalskiet al. Journal of Organometallic Chemistry, 2007, 692 (6), pp.1315-1326. ⟨10.1016/j.jorganchem.2006.10.041⟩ Article dans une revue istex hal-01230402v1
Modification of the estrogenic properties of diphenols by the incorporation of ferrocene. Generation of antiproliferative effects in vitro A Vessieres,Siden Top,Pascal Pigeon,E Hillard,L Boubekeret al. Journal of Medicinal Chemistry, 2005, 48 (12), pp.3937-3940. ⟨10.1021/jm050251o⟩ Article dans une revue hal-01230403v1
Selective estrogen receptor modulators in the ruthenocene series. Synthesis and biological behavior Pascal Pigeon,Siden Top,Anne Vessières,Michel Huché,Elisabeth A. Hillardet al. Journal of Medicinal Chemistry, 2005, 48 (8), pp.2814-2821. ⟨10.1021/jm049268h⟩ Article dans une revue hal-00093015v1
Selective estrogen-receptor modulators (SERMs) in the cyclopentadienylrhenium tricarbonyl series: Synthesis and biological behaviour Siden Top,A Vessieres,Pascal Pigeon,Mn Rager,M Hucheet al. ChemBioChem, 2004, 5 (8), pp.1104-1113. ⟨10.1002/cbic.200400067⟩ Article dans une revue istex hal-01230404v1
A short route to cyclopentadienyl tricarbonylrhenium substituted derivatives F Le Bideau,J Henique,Pascal Pigeon,Jm Joerger,Siden Topet al. Journal of Organometallic Chemistry, 2003, 668 (1-2), pp.140-144. ⟨10.1016/S0022-328X(02)02090-9⟩ Article dans une revue hal-01230405v1
Intramolecular addition of a hydroxyl to a N-acyliminium system. Application to the synthesis of isoindolo[2,1-a][3,1]benzoxazine and isoindolo[1,2-c][2,4] benzoxazepine derivatives Pascal Pigeon,Jana Sikoraiova,S Marchalin,Bernard Decroix Heterocycles, 2002, 56 (1-2), pp.129-138. ⟨10.3987/COM-01-S(K)5⟩ Article dans une revue hal-01230406v1
Study of a 1,6-hydride shift in an open chain of hydroxylactam-triarylcarbinols Pascal Pigeon,Aïcha Mamouni,Jana Sikoraiova,Stefan Marchalin,Bernard Decroix Tetrahedron, 2001, 57 (23), pp.4939-4943. ⟨10.1016/S0040-4020(01)00437-9⟩ Article dans une revue hal-01230408v1
First anti-oestrogen in the cyclopentadienyl rhenium tricarbonyl series. Synthesis and study of antiproliferative effects Gérard Jaouen,Siden Top,Anne Vessieres,Pascal Pigeon,Guy Leclercqet al. Chemical Communications, 2001, 4, pp.383-384. ⟨10.1039/b009553m⟩ Article dans une revue hal-01230409v1
Thieno[2′,3′:5,6]azepino[2,1- a ]isoindolones from hydroxylactam-alcohols via N -acyliminium ion olefin cyclization Pascal Pigeon,Mohamed Othman,Bernard Decroix Journal of Heterocyclic Chemistry, 2001, 38 (1), pp.35 - 39. ⟨10.1002/jhet.5570380105⟩ Article dans une revue hal-01230407v1
Quinoxalines, benzodiazepines and benzodiazocines fused to pyrrole and isoindole via N-acyliminium ion aromatic cyclization Mohamed Othman,Pascal Pigeon,Pierre Netchitaïlo,Abdel Daich,Bernard Decroix Heterocycles, 2000, 52 (1), pp.273-281. ⟨10.3987/COM-99-S21⟩ Article dans une revue hal-01230410v1
Polycyclic systems: Synthesis of isoindolo[2,1-b]pyrrolo[1,2-d] [2,4]benzodiazocine and isoindolo[1,2-d]pyrrolo[1,2-a][1,5]benzodiazocine Mohamed Othman,Pascal Pigeon,Bernard Decroix Journal of Heterocyclic Chemistry, 1999, 36 (3), pp.735-738. ⟨10.1002/jhet.5570360326⟩ Article dans une revue hal-01230411v1
Acyliminium ion-olefin cyclization leading to isoindolo [2,1-a]quinoline derivatives Pascal Pigeon,Mohamed Othman,Pierre Netchitaïlo,Bernard Decroix Journal of Heterocyclic Chemistry, 1999, 36 (3), pp.691-695. ⟨10.1002/jhet.5570360319⟩ Article dans une revue hal-01230412v1
Synthesis and reduction of thieno[2 `,3 `(3 `,2 ` or 3 `,4 `): 5,6]-azocino[2,1-a]isoindole-7,13-diones Mohamed Othman,Pascal Pigeon,Bernard Decroix Journal of Heterocyclic Chemistry, 1998, 35 (6), pp.1429-1433. ⟨10.1002/jhet.5570350635⟩ Article dans une revue istex hal-01230418v1
New fused lactones from indolizinediones via N-acyliminium ions Mohamed Othman,Pascal Pigeon,Bernard Decroix Tetrahedron, 1998, 54 (30), pp.8737-8744. ⟨10.1016/S0040-4020(98)00468-2⟩ Article dans une revue hal-01230415v1
Synthesis of benzo(or furo)[5,6]azepino[2,1-a]isoindolone derivatives: pi-cyclisations of N-acyliminium ions. Adam Daich,Stefan Marchalin,Pascal Pigeon,Bernard Decroix Tetrahedron Letters, 1998, 39 (50), pp.9187-9190. ⟨10.1016/S0040-4039(98)02075-9⟩ Article dans une revue istex hal-01230414v1
Selective access to N-aryl or N-alkyl derivatives of isoindolo[2,1-b][2,4]benzo(or thieno)diazepines Pascal Pigeon,Mohamed Othman,Pierre Netchitaïlo,Bernard Decroix Tetrahedron, 1998, 54 (8), pp.1497-1506. ⟨10.1016/S0040-4020(97)10359-3⟩ Article dans une revue hal-01230416v1
Novel approach to isoindolo[2,1-a]quinolines Pascal Pigeon,Bernard Decroix Synthetic Communications, 1998, 28 (13), pp.2507-2516. ⟨10.1080/00397919808004302⟩ Article dans une revue hal-01230413v1
Diisoindolothieno[2,4]diazepines via a diastereoselective N-acyliminium ion cyclization Pascal Pigeon,Bernard Decroix Tetrahedron Letters, 1998, 39 (47), pp.8659-8662. ⟨10.1016/S0040-4039(98)01979-0⟩ Article dans une revue hal-01230417v1
Introduction of a carboxymethylamino (or oxy or thio) group in the 3 position of 2-aryl (or arylmethyl) isoindol-1-ones from alpha hydroxylactams Pascal Pigeon,Bernard Decroix Synthetic Communications, 1997, 27 (8), pp.1423-1431. ⟨10.1080/00397919708006073⟩ Article dans une revue hal-01230420v1
Synthesis of dibenz[c,e]azepine and benzo[e]thieno[c]azepine via N-acyliminium ion cyclization Pascal Pigeon,Bernard Decroix Tetrahedron Letters, 1997, 38 (6), pp.1041-1042. ⟨10.1016/S0040-4039(96)02497-5⟩ Article dans une revue hal-01230421v1
Tetracyclic systems: Synthesis of isoindolo[1,2-b]thieno[2,3(3,2 or 3,4)-e][1,3]thiazocines and isoindolo[2,1-a]thieno[2,3(3,2 or 3,4)-f][1,4] and [1,5]diazocines Pascal Pigeon,Bernard Decroix Journal of Heterocyclic Chemistry, 1997, 34 (2), pp.375-380. ⟨10.1002/jhet.5570340203⟩ Article dans une revue hal-01230425v1
Intramolecular amidoalkylation cyclizations in synthesis of novel pyrrolo(or isoindolo)thieno[2]benzazepines Aïcha Mamouni,Pascal Pigeon,Abdel Adam Daïch,Bernard Decroix Journal of Heterocyclic Chemistry, 1997, 34 (5), pp.1495-1499. ⟨10.1002/jhet.5570340519⟩ Article dans une revue hal-01230424v1
A new access to isoindolo[2,1-b][2,4]benzodiazepines through an N-acyliminium ion amide cyclization Pascal Pigeon,Bernard Decroix Tetrahedron Letters, 1997, 38 (17), pp.2985-2988. ⟨10.1016/S0040-4039(97)00539-X⟩ Article dans une revue hal-01230422v1
Synthèses de thiéno[2’,3’(ou 3’,2’):5,6]azépino[2,1-a]isoindol-6-ones diversement substituées Pascal Pigeon,Bernard Decroix Bulletin de la Societe Chimique de France, 1997, 134 (2), pp.153-157 Article dans une revue hal-01230419v1
Acyliminium ion cyclizations: Synthesis of thieno[2',3':3,4]pyrrolo[2,1-a]isoindolone and benzo[a]thieno[2,3(3,2 or 3,4)-g]indolizinones Mohamed Othman,Pascal Pigeon,Bernard Decroix Tetrahedron, 1997, 53 (7), pp.2495-2504. ⟨10.1016/S0040-4020(96)01196-9⟩ Article dans une revue hal-01230423v1
Synthesis of thieno[2′,3′(3′,4′ or 3′,2′):5,6]azepino[2,1-a]isoindolediones from N-Thienyl-2(3)-ylmethylphthalimides Pascal Pigeon,Bernard Decroix Journal of Heterocyclic Chemistry, 1996, 33 (1), pp.129-135. ⟨10.1002/jhet.5570330123⟩ Article dans une revue istex hal-01218990v1
Benzothienoindolizidines via intramolecular aryl radical cyclization or palladium catalyzed cyclization Pascal Pigeon,Bernard Decroix Tetrahedron Letters, 1996, 37 (43), pp.7707-7710. ⟨10.1016/0040-4039(96)01738-8⟩ Article dans une revue hal-01218988v1

Communication dans un congrès (9)

Surface-functionalization with NFL peptide of Ferrocifen loaded Lipid NanoCapsules: preferential entry into human glioblastoma cells Reatul Karim,Elise Lepeltier,Lucille Esnault,Pascal Pigeon,Laurent Lemaireet al. 9th International Symposium on Bioorganometallic Chemistry, Aug 2019, York, United Kingdom Communication dans un congrès hal-02617951v1
Nanoassemblies formed by polyarginine-ferrocifen conjugates for lung cancer treatment Léna Guyon,Elise Lepeltier,Brice Calvignac,Nolwenn Lautram,Bénédicte Lelièvreet al. SF Nano, Dec 2018, Montpellier, France Communication dans un congrès hal-02617897v1
Nanoassemblies formed by cell-penetrating peptides and ferrocifens for lung cancer treatment Léna Guyon,Elise Lepeltier,Gérard Jaouen,Pascal Pigeon,Didier Perinoet al. 11th World Meeting on Pharmaceutics, Biopharmaceutics and Pharmaceutical Technology, 2018, Grenade, Spain Communication dans un congrès hal-02616031v1
Self-assembly of prodrugs formed by cell-penetrating peptide and ferrocifen for lung cancer treatment Léna Guyon,Elise Lepeltier,Gérard Jaouen,Pascal Pigeon,Didier Perinoet al. Imaging and therapeutic targeting in cancerology: New advances and trends in preclinical and clinical studies, 2018, Le Bono, France Communication dans un congrès hal-02616026v1
Targeted-internalization of NFL-peptide functionalized lipid nanocapsules into human glioblastoma cells Reatul Karim,Elise Lepeltier,Lucille Esnault,Pascal Pigeon,Laurent Lemaireet al. 11 th World Meeting on Pharmaceutics, Biopharmaceutics and Pharmaceutical, 2018, Grenade, Spain Communication dans un congrès hal-02616018v1
Surface-functionalization with NFL peptide of Lipid NanoCapsules LNC: preferential entry into human glioblastoma cells Reatul Karim,Elise Lepeltier,Lucille Esnault,Pascal Pigeon,Laurent Lemaireet al. SF Nano 2017, 2017, Bordeaux, France Communication dans un congrès hal-02616007v1
Synthesis of new polyheterocycles via N-acyliminium ion aromatic cyclization Adam Daïch,Mohamed Othman,Pascal Pigeon,Bernard Decroix Ve Rencontre Nationale de Chimie Hétérocyclique (5ème RNCH), May 2002, Kenitra, Morocco Communication dans un congrès hal-02568008v1
π-Cationic cyclisations of N-acyliminium ions from imide-ester functionality: Use of olefin as nucleophile Adam Daïch,Mohamed Othman,Pascal Pigeon,Bernard Decroix Colloque Anglo Normand de Chimie Organique (ANORCQ V), May 1999, Forges-les-Eaux, France Communication dans un congrès hal-02568104v1
Cyclisation intramoleculaire via amidoalkylation: Synthèse de nouvelles pyrrolo(ou isoindolo)thieno[2]benzazepines et thieno[f]indolizines Adam Daïch,Aïcha Mamouni,Pascal Pigeon,Bernard Decroix Congrès IRCOF "Intramuros", Jun 1997, Mont-Saint-Aignan, France Communication dans un congrès hal-02567914v1

Poster de conférence (7)

Peptide-decorated ferrocifen lipid nanocapsules for the targeting of multidrug resistant ovarian adenocarcinoma Andrea Bottasso,Pierre Idlas,Milad Baroud,Pascal Pigeon,Gérard Jaouenet al. SFNano 2022, Dec 2022, Strasbourg, France Poster de conférence hal-04109714v1
Physico-chemical characterization of ferrocifen loaded lipid nanocapsules: different drug delivery systems depending on succinimido-ferrociphenol structure Pierre Idlas,Elise Lepeltier,Pascal Pigeon,Gérard Jaouen,Catherine Passirani SFNano2021, Annual Meeting, Dec 2021, ANGERS, France Poster de conférence hal-03552215v1
Synthesis and characterization of cell-penetrating peptide-ferrocifen self-assemblies Léna Guyon,Elise Lepeltier,Jean-Christophe Gimel,Brice Calvignac,Florence Franconiet al. IUPAC, Jul 2019, Paris, France Poster de conférence hal-02617358v1
Is dynamic light scattering a good method to characterize self-assemblies of cell penetrating peptide-ferrocifen conjugates? Léna Guyon,Elise Lepeltier,Jean-Christophe Gimel,Brice Calvignac,Florence Franconiet al. SF Nano, Dec 2019, Dijon, France Poster de conférence hal-02617249v1
Nanoparticules, chargées en ferrocifenes, pour le traitement du cancer du poumon par nébulisation Léna Guyon,Elise Lepeltier,Gérard Jaouen,Pascal Pigeon,Didier Perinoet al. 12èmes journée du Cancéropôle Grand Ouest, 2018, Vannes, France. , 2018 Poster de conférence hal-02616022v1
Self-assemblies formed by cell-penetrating peptide and ferrocifen for lung cancer treatment Léna Guyon,Elise Lepeltier,Gérard Jaouen,Pascal Pigeon,Didier Perinoet al. Journée scientifique de la SFR ICAT4208, 2018, Non spécifié, France. , 2018 Poster de conférence hal-02616014v1
Self-assemblies consisting of cell penetrating peptides and ferrocifen for the treatment of lung carcinoma Léna Guyon,Elise Lepeltier,Gérard Jaouen,Pascal Pigeon,Didier Perinoet al. 4th SFNano Annual Meeting, 2017, Bordeaux, France. , 2017 Poster de conférence hal-02615994v1

Logiciel (1)

CDModelTree (V1): Manipulation of a cyclodextrin-ferrociphenol supramolecular models database using a PHP web application Pascal Pigeon 2022, ⟨swh:1:dir:5c05be4fc1a1a2d4ca16bc48323231bb28379dec;origin=https://hal.archives-ouvertes.fr/hal-03991394;visit=swh:1:snp:438a3325327d8bef3a099271997a0dbdeca32da2;anchor=swh:1:rel:4ec1d7207a58cc63963137f2e79030f04cfdec96;path=/⟩ Logiciel hal-03991394v1