pascal Drane

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Publications

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An autoinhibited state of 53BP1 revealed by small molecule antagonists and protein engineering

Gaofeng Cui , Maria Victoria Botuyan , Pascal Drané , Qi Hu , Benoît Bragantini et al.
Nature Communications, 2023, 14, pp.6091. ⟨10.1038/s41467-023-41821-6⟩
Article dans une revue hal-05442137 v1
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Mechanism of 53BP1 activity regulation by RNA-binding TIRR and a designer protein

Maria Victoria Botuyan , Gaofeng Cui , Pascal Drané , Catarina Oliveira , Alexandre Detappe et al.
Nature Structural and Molecular Biology, 2018, 25, pp.591-600. ⟨10.1038/s41594-018-0083-z⟩
Article dans une revue hal-05442177 v1

DYNLL1 binds to MRE11 to limit DNA end resection in BRCA1-deficient cells

Yizhou Joseph He , Khyati Meghani , Marie-Christine Caron , Chunyu Yang , Daryl Ronato et al.
Nature, 2018, 563 (7732), pp.522-526. ⟨10.1038/s41586-018-0670-5⟩
Article dans une revue hal-02352382 v1

TIRR regulates 53BP1 by masking its histone methyl-lysine binding function

Pascal Drané , Marie-Eve Brault , Gaofeng Cui , Khyati Meghani , Shweta Chaubey et al.
Nature, 2017, 543 (7644), pp.211-216. ⟨10.1038/nature21358⟩
Article dans une revue hal-03682263 v1
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Key clinical beam parameters for nanoparticle-mediated radiation dose amplification

Alexandre Detappe , Sijumon Kunjachan , Pascal Drané , Shady Kotb , Marios Myronakis et al.
Scientific Reports, 2016, 6, pp.34040. ⟨10.1038/srep34040⟩
Article dans une revue hal-01400077 v1

Advanced multimodal nanoparticles delay tumor progression with clinical radiation therapy

Alexandre Detappe , Sijumon Kunjachan , Lucie Sancey , Vincent Motto-Ros , Douglas Biancur et al.
Journal of Controlled Release, 2016, 238, pp.103 - 113. ⟨10.1016/j.jconrel.2016.07.021⟩
Article dans une revue istex hal-01405826 v1

The death-associated protein DAXX is a novel histone chaperone involved in the replication-independent deposition of H3.3

Pascal Drané , Khalid Ouararhni , Arnaud Depaux , Muhammad Shuaib , Ali Hamiche
Genes and Development, 2010, 24 (12), pp.1253-1265. ⟨10.1101/gad.566910⟩
Article dans une revue hal-04031319 v1

A comprehensive study of p53 transcriptional activity in thymus and spleen of γ irradiated mouse: High sensitivity of genes involved in the two main apoptotic pathways

Sandra Alvarez , Pascal Drané , Anne Meiller , Marlene Bras , Valerie Deguin-Chambon et al.
International Journal of Radiation Biology, 2009, 82 (11), pp.761-770. ⟨10.1080/09553000600949624⟩
Article dans une revue hal-03658733 v1

Cockayne syndrome B protein regulates the transcriptional program after UV irradiation.

Luca Proietti-De-Santis , Pascal Drané , Jean-Marc Egly
EMBO Journal, 2006, 25 (9), pp.1915-23. ⟨10.1038/sj.emboj.7601071⟩
Article dans une revue hal-00188110 v1

Dysregulation of the peroxisome proliferator-activated receptor target genes by XPD mutations.

Emmanuel Compe , Pascal Drané , Camille Laurent , Karin Diderich , Cathy Braun et al.
Molecular and Cellular Biology, 2005, 25 (14), pp.6065-76. ⟨10.1128/MCB.25.14.6065-6076.2005⟩
Article dans une revue hal-00187493 v1

Selective regulation of vitamin D receptor-responsive genes by TFIIH

Pascal Drané , Emmanuel Compe , Philippe Catez , Pierre Chymkowitch , Jean-Marc Egly
Molecular Cell, 2004, 16 (2), pp.187-197. ⟨10.1016/j.molcel.2004.10.007⟩
Article dans une revue hal-04138409 v1