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Pascale Chavatte-Palmer

Pascale Chavatte-Palmer, INRAE Director of the BREED Research unit, University Paris-Saclay, INRAE, University Versailles Saint-Quentin, Ecole nationale Vétérinaire d'Alfort France
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Présentation

**Directrice de l'unité Mixte de Recherches Biologie de la Reproduction, Environnement, Epigénétique et Développement** Université Paris-Saclay, UVSQ, INRAE, BREED, 78350, Jouy-en-Josas, France Ecole Nationale Vétérinaire d’Alfort, BREED, 94700, Maisons-Alfort, France Initially trained as a veterinarian, I specialized in animal, and particularly equine reproduction with a focus on pregnancy and neonatology through my internship, residency and PhD, post-doctoral fellowship and initial position. After my recruitment at AgroParisTech and subsequently INRAE in France, I have been more widely focusing on feto-placental development and the developmental origins of health and disease (DOHaD), with a dual purpose in agriculture and as biomedical models. The aim of my research is to understand the role of the placenta in the programming of long term post-natal health, in the context of the developmental origins of health and diseases. First as a veterinarian and subsequently to be able to perform longitudinal studies in research animals, I have also been developing in vivo imaging technologies such as ultrasound and Doppler to assess placental feto-placental development and placental perfusion. After having led a research group at the National Institute of Agronomical Research (now INRAE), with a mean of 12 permanent staff for the past 14 years, I have recently taken the lead of the new Biology of Reproduction, Environment, Epigenetics and Development (BREED) research unit (90 permanent staff), focusing on the development of the mammalian embryo from the formation of the egg cell to birth and development to adulthood. Projects range from fundamental studies on the functioning of the genome during embryo and fetal growth to applied research on the effects of the environment at large on development in the agronomic, veterinary and biomedical fields. The scientific objective is to understand and control the mechanisms of epigenetic programming during prenatal life, leading to the birth of a healthy, fertile and robust individual, able to adapt to changes in his environment. Meanwhile, I pursue my own research programs on effects of maternal and post-natal breeding conditions, including nutrition, on metabolic and osteoarticular outcomes in the foal. I have served as PI or co-PIU to several national and European research projects (see section D).

Publications

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"emilie-derisoud"
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Caractérisation ultra structurale du placenta équin après supplémentation alimentaire en arginine des juments au dernier tiers de la gestation

Audrey Geeverding , Josiane Aioun , Morgane Robles , Michèle Dahirel , Marie-Christine Aubrière
17.Journées de formation du RCCM (Réseau des Centres Communs de Microscopie), Centre National de la Recherche Scientifique (CNRS). FRA., Jun 2018, Clermont-Ferrand, France
Communication dans un congrès hal-02187460v1
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Effets de la supplémentation alimentaire en arginine chez les juments gravides sur le métabolisme maternal, la fonction placentaire et le poids de naissance des poulains

Pascale Chavatte-Palmer , Morgane Robles , Emilie Derisoud , Audrey Geeverding , Josiane Aioun
4. Congrès de la SF-Dohad, Société Francophone de la Dohad., Nov 2018, Grenoble, France. pp.120
Communication dans un congrès hal-02735937v1

A periconceptional maternal hyperglycemia disrupts the feto-placental membrane fatty acid profiles in a rabbit model

Delphine Rousseau-Ralliard , Emilie Derisoud , Anne Couturier-Tarrade , Roselyne Brat , Audrey Rolland
International conference on Developmental Origins of Adiposity and Long-Term Health, Early Nutrition Academy. DEU., Mar 2014, Munich, Germany. 106 p
Communication dans un congrès hal-02744199v1
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A short periconceptional exposure to maternal type-1 diabetes is sufficient to disrupt the feto-placental phenotype in a rabbit model

Delphine Rousseau-Ralliard , Anne Couturier-Tarrade , René Thieme , Roselyne Brat , Audrey Rolland
Journée Aviesan, Jun 2019, Paris, France. , 2019, ITMO " Translational research on diabetic cardiomyopathy"
Poster de conférence hal-02733977v1

Effets de la supplémentation alimentaire en arginine chez les juments gravides sur le métabolisme maternel, la fonction placentaire et le poids de naissance des poulains.

Pascale Chavatte-Palmer , Morgane Robles , Emilie Derisoud , Audrey Geeverding , Josiane Aioun
7. Rencontre du Groupe de la Francophonie Placentaire 2019, Mar 2019, Paris, France. 36p, 2019
Poster de conférence hal-02264920v1
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A short periconceptional exposure to maternal type-1 diabetes is sufficient to disrupt the feto-placentalphenotypein a rabbit model

Delphine Rousseau-Ralliard , Anne Couturier-Tarrade , René Thieme , Roselyne Brat , Audrey Rolland
IFPA 2018, Sep 2018, Tokyo, Japan. , Placenta, 9, pp.93, 2018, Abstracts for the forthcoming International Federation of Placenta Associations Meeting, Tokyo, Japan
Poster de conférence hal-02734076v1
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Effects of dietary arginine supplementation to primiparous mares in the last third of gestation on foal birthweight and placental function

Emilie Derisoud , Morgane Robles , Audrey Geeverding , Josiane Aioun , C. Dubois
IFPA 2018, Sep 2018, Tokyo, France. , Placenta, 69, pp.93, 2018, Abstracts for the forthcoming International Federation of Placenta Associations Meeting, Tokyo, Japan September 21 - 24, 2018
Poster de conférence hal-02735438v1

A periconceptional maternal hyperglycemia disrupts the feto-placental membrane fatty acid profiles in a rabbit model

Delphine Rousseau-Ralliard , Emilie Derisoud , Anne Couturier-Tarrade , Roselyne Brat , Audrey Rolland
Meeting of the International Federation of Placenta Associations (IFPA), Sep 2014, Paris, France. Elsevier, Placenta, 35 (9), 120 p., 2014, IFPA EPG 2014 "Fetal placental-maternal crosstalk and pregnancy outcome". ⟨10.1016/j.placenta.2014.06.096⟩
Poster de conférence hal-02740945v1

A periconceptional maternal hyperglycemia disrupts the feto-placental membrane fatty acid profiles in a rabbit model

Delphine Rousseau-Ralliard , Emilie Derisoud , Anne Couturier-Tarrade , Roselyne Brat , Audrey Rolland
Epiconcept Workshop 2014, Epigenomic Toolbox: from Methods to Models, May 2014, Las Palmas, Spain. Cost Office, 2014, Epigenetics and Periconception Environment
Poster de conférence hal-02741084v1