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Pascale Chavatte-Palmer

Pascale Chavatte-Palmer, INRAE Director of the BREED Research unit, University Paris-Saclay, INRAE, University Versailles Saint-Quentin, Ecole nationale Vétérinaire d'Alfort France
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Présentation

**Directrice de l'unité Mixte de Recherches Biologie de la Reproduction, Environnement, Epigénétique et Développement** Université Paris-Saclay, UVSQ, INRAE, BREED, 78350, Jouy-en-Josas, France Ecole Nationale Vétérinaire d’Alfort, BREED, 94700, Maisons-Alfort, France Initially trained as a veterinarian, I specialized in animal, and particularly equine reproduction with a focus on pregnancy and neonatology through my internship, residency and PhD, post-doctoral fellowship and initial position. After my recruitment at AgroParisTech and subsequently INRAE in France, I have been more widely focusing on feto-placental development and the developmental origins of health and disease (DOHaD), with a dual purpose in agriculture and as biomedical models. The aim of my research is to understand the role of the placenta in the programming of long term post-natal health, in the context of the developmental origins of health and diseases. First as a veterinarian and subsequently to be able to perform longitudinal studies in research animals, I have also been developing in vivo imaging technologies such as ultrasound and Doppler to assess placental feto-placental development and placental perfusion. After having led a research group at the National Institute of Agronomical Research (now INRAE), with a mean of 12 permanent staff for the past 14 years, I have recently taken the lead of the new Biology of Reproduction, Environment, Epigenetics and Development (BREED) research unit (90 permanent staff), focusing on the development of the mammalian embryo from the formation of the egg cell to birth and development to adulthood. Projects range from fundamental studies on the functioning of the genome during embryo and fetal growth to applied research on the effects of the environment at large on development in the agronomic, veterinary and biomedical fields. The scientific objective is to understand and control the mechanisms of epigenetic programming during prenatal life, leading to the birth of a healthy, fertile and robust individual, able to adapt to changes in his environment. Meanwhile, I pursue my own research programs on effects of maternal and post-natal breeding conditions, including nutrition, on metabolic and osteoarticular outcomes in the foal. I have served as PI or co-PIU to several national and European research projects (see section D).

Publications

"eric-pailhoux"
Image document

L’édition du génome des animaux d’élevage dans le monde: quelles applications, quelles règlementations

Pascale Chavatte-Palmer , Geneviève Jolivet , Eric Pailhoux
La révolution CRISPR-Cas 9 en élevage: Les nouvelles techniques de ré-écriture du génome des animaux de rente par mutagénèse ciblée ont elles une place en Elevage, Académie d'Agriculture de France (AAF). FRA., Oct 2018, Paris, France
Communication dans un congrès hal-02737803v1

Effect of maternal periconceptional undernutrition on male offspring physiology and testicular development

Audrey Rosefort , Nathalie Debus , Gilles Viudes , Sylvaine Camous , Eric Pailhoux
Annual Conference of the International Embryo Transfer Society, Jan 2011, Orlando (Florida), United States. pp.219
Communication dans un congrès hal-01019349v1

Effect of maternal periconceptional undernutrition on male offspring physiology and testicular development: a sheep model

Audrey Rosefort , Nathalie Debus , Gilles G. Viudes , Sylvaine S. Camous , Eric Pailhoux
3. General Meeting of GEMINI:Maternal Communication with Gametes and Embryo, Oct 2010, Soustons, France
Communication dans un congrès hal-02754446v1

The use of sheep as biomedical models

Pascale Chavatte-Palmer , Olivier Morel , Yvan Heyman , Eric Pailhoux , Bérengère Laporte
61. Annual Meeting of the European Association for Animal Production (EAAP), Aug 2010, Heralkion, Greece
Communication dans un congrès hal-01173499v1

Maternal periconceptional undernutrition in sheep: effects on male lambs' physiology and reproduction

Audrey Rosefort , Nathalie Debus , Gilles G. Viudes , Sylvaine S. Camous , Eric Pailhoux
26. Annual Meeting AETE (Association Européeenne de Transfert Embryonnaire), Sep 2010, Kuopio, Finland
Communication dans un congrès hal-02752535v1

Maternal periconceptional undernutrition in sheep: effects on male lambs' physiology and reproduction

Audrey Rosefort , Nathalie Debus , Gilles G. Viudes , Sylvaine S. Camous , Eric Pailhoux
13. International Symposium on Perinatal Nephrology:Early Determinants of Renal Function & Disease at Adulthood, Jun 2010, Marseille, France. pp.*
Communication dans un congrès hal-02817016v1

The use of ruminant models in biomedical research

Olivier Morel , Yvan Heyman , Bérengère Laporte , Eric Pailhoux , Michel M. Bonneau
ERIN Stakeholders' Conference, Polish National Research Institute of Animal Production. POL., Mar 2010, Cracow-Balice, Poland
Communication dans un congrès hal-02755267v1

Genomic instability following somatic cell nuclear transfer in cattle

Beatrice de Montera , Jean-Francois Oudin , Luc Jouneau , Guy Noé , Pascale Chavatte-Palmer
60. Annual Meeting of the European Association for Animal Production (EAAP), Aug 2009, Barcelona, Spain
Communication dans un congrès hal-02752742v1
Image document

Effect of perinatal undernutrition in Merinos d’Arles ewes on physiology and reproductive function

Sylvaine S. Camous , Audrey Rosefort , Valérie Berthelot , Eric Pailhoux , Philippe Hassoun
Cambridge University Press. Colloque SF-DOHaD, Nov 2012, Paris, France. Cambridge University Press, Journal of Developmental Origins of Health and Disease, 4 (Supplement 1) (S1), pp.S12-S13, 2013, Founding meeting of SF-DOHaD
Poster de conférence hal-02745038v1