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Pascale Chavatte-Palmer
Pascale Chavatte-Palmer, INRAE
Director of the BREED Research unit, University Paris-Saclay, INRAE, University Versailles Saint-Quentin, Ecole nationale Vétérinaire d'Alfort
France
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Documents
Affiliations actuelles
- 1003282
Identifiants chercheurs
- pascale-chavatte-palmer
- ResearcherId : K-7349-2012
- 0000-0002-4581-6092
- IdRef : 153497998
- ResearcherId : http://www.researcherid.com/rid/K-7349-2012
Présentation
**Directrice de l'unité Mixte de Recherches Biologie de la Reproduction, Environnement, Epigénétique et Développement**
Université Paris-Saclay, UVSQ, INRAE, BREED, 78350, Jouy-en-Josas, France
Ecole Nationale Vétérinaire d’Alfort, BREED, 94700, Maisons-Alfort, France
Initially trained as a veterinarian, I specialized in animal, and particularly equine reproduction with a focus on pregnancy and neonatology through my internship, residency and PhD, post-doctoral fellowship and initial position. After my recruitment at AgroParisTech and subsequently INRAE in France, I have been more widely focusing on feto-placental development and the developmental origins of health and disease (DOHaD), with a dual purpose in agriculture and as biomedical models. The aim of my research is to understand the role of the placenta in the programming of long term post-natal health, in the context of the developmental origins of health and diseases. First as a veterinarian and subsequently to be able to perform longitudinal studies in research animals, I have also been developing in vivo imaging technologies such as ultrasound and Doppler to assess placental feto-placental development and placental perfusion. After having led a research group at the National Institute of Agronomical Research (now INRAE), with a mean of 12 permanent staff for the past 14 years, I have recently taken the lead of the new Biology of Reproduction, Environment, Epigenetics and Development (BREED) research unit (90 permanent staff), focusing on the development of the mammalian embryo from the formation of the egg cell to birth and development to adulthood. Projects range from fundamental studies on the functioning of the genome during embryo and fetal growth to applied research on the effects of the environment at large on development in the agronomic, veterinary and biomedical fields. The scientific objective is to understand and control the mechanisms of epigenetic programming during prenatal life, leading to the birth of a healthy, fertile and robust individual, able to adapt to changes in his environment. Meanwhile, I pursue my own research programs on effects of maternal and post-natal breeding conditions, including nutrition, on metabolic and osteoarticular outcomes in the foal. I have served as PI or co-PIU to several national and European research projects (see section D).
Publications
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Hyperlipidic hypercholesterolemic diet in prepubertal rabbits affects gene expression in the embryo, restricts fetal growth and increases offspring susceptibility to obesityTheriogenology, 2011, 75 (2), pp.287-299. ⟨10.1016/j.theriogenology.2010.08.015⟩
Article dans une revue
hal-01019329v1
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Developmental effects of cholesterol-enriched hyperlipidic diets in rabbitsAnnual Conference of the International Embryo Transfer Society, Jan 2009, San Diego, California, United States. pp.143
Communication dans un congrès
hal-02754474v1
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Development of obesity in rabbit offspring from dams fed a hyperlipidic hypercholesterolemic diet15. European Congress on Obesity, Apr 2007, Budapest, Hungary
Communication dans un congrès
hal-01173439v1
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Effect of a hyperlipidic hypercholesterolemic diet in pubertal does on fetal and post-natal development: Preliminary results for the validation of a rabbit model.2. Workshop on Embryonic and Fetal Nutrition, May 2006, Ravello, Italy
Communication dans un congrès
hal-02757097v1
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Effect of a hyperlipidic hypercholesterolaedomic diet in pubertal does on fetal and post natal development33. Annual Meeting of the Fetal and Neonatal Physiological Society, Sep 2006, Cambridge, United Kingdom
Communication dans un congrès
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Effets sur la descendance de la lapine juvénile d'un régime hyperlipidique hypercholestérolémiqueJournées de Restitution des projets financés sur credits incitatifs du Département PHASE, Sep 2006, Tours, France. pp.93
Communication dans un congrès
hal-02817367v1
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Developmental effects of cholesterol-enriched hyperlipidic diets in rabbits.New Inroads to Child Health (NICHe) Conference 2009., May 2009, Göteberg, Sweden. n.p., 2009
Poster de conférence
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