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Pascale Chavatte-Palmer

Pascale Chavatte-Palmer, INRAE Director of the BREED Research unit, University Paris-Saclay, INRAE, University Versailles Saint-Quentin, Ecole nationale Vétérinaire d'Alfort France
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Présentation

**Directrice de l'unité Mixte de Recherches Biologie de la Reproduction, Environnement, Epigénétique et Développement** Université Paris-Saclay, UVSQ, INRAE, BREED, 78350, Jouy-en-Josas, France Ecole Nationale Vétérinaire d’Alfort, BREED, 94700, Maisons-Alfort, France Initially trained as a veterinarian, I specialized in animal, and particularly equine reproduction with a focus on pregnancy and neonatology through my internship, residency and PhD, post-doctoral fellowship and initial position. After my recruitment at AgroParisTech and subsequently INRAE in France, I have been more widely focusing on feto-placental development and the developmental origins of health and disease (DOHaD), with a dual purpose in agriculture and as biomedical models. The aim of my research is to understand the role of the placenta in the programming of long term post-natal health, in the context of the developmental origins of health and diseases. First as a veterinarian and subsequently to be able to perform longitudinal studies in research animals, I have also been developing in vivo imaging technologies such as ultrasound and Doppler to assess placental feto-placental development and placental perfusion. After having led a research group at the National Institute of Agronomical Research (now INRAE), with a mean of 12 permanent staff for the past 14 years, I have recently taken the lead of the new Biology of Reproduction, Environment, Epigenetics and Development (BREED) research unit (90 permanent staff), focusing on the development of the mammalian embryo from the formation of the egg cell to birth and development to adulthood. Projects range from fundamental studies on the functioning of the genome during embryo and fetal growth to applied research on the effects of the environment at large on development in the agronomic, veterinary and biomedical fields. The scientific objective is to understand and control the mechanisms of epigenetic programming during prenatal life, leading to the birth of a healthy, fertile and robust individual, able to adapt to changes in his environment. Meanwhile, I pursue my own research programs on effects of maternal and post-natal breeding conditions, including nutrition, on metabolic and osteoarticular outcomes in the foal. I have served as PI or co-PIU to several national and European research projects (see section D).

Publications

"laurence-lamothe"

Developmental effects of cholesterol-enriched hyperlipidic diets in rabbits

Pascale Chavatte-Palmer , Patrice Laigre , Michèle Dahirel , Olivier Picone , Laurence Lamothe
Annual Conference of the International Embryo Transfer Society, Jan 2009, San Diego, California, United States. pp.143
Communication dans un congrès hal-02754474v1

Development of obesity in rabbit offspring from dams fed a hyperlipidic hypercholesterolemic diet

Pascale Chavatte-Palmer , Marie Baron , Jean Luc Servely , Patrice Laigre , Olivier Picone
15. European Congress on Obesity, Apr 2007, Budapest, Hungary
Communication dans un congrès hal-01173439v1

Effect of a hyperlipidic hypercholesterolemic diet in pubertal does on fetal and post-natal development: Preliminary results for the validation of a rabbit model.

Marie Baron , Jean Luc Servely , Patrice Laigre , Laurence Fortun-Lamothe , Jean Paul J. P. Renard
2. Workshop on Embryonic and Fetal Nutrition, May 2006, Ravello, Italy
Communication dans un congrès hal-02757097v1

Effect of a hyperlipidic hypercholesterolaedomic diet in pubertal does on fetal and post natal development

Pascale Chavatte-Palmer , Marie Baron , Jean Luc Servely , Patrice Laigre , Laurence Fortun-Lamothe
33. Annual Meeting of the Fetal and Neonatal Physiological Society, Sep 2006, Cambridge, United Kingdom
Communication dans un congrès hal-02753288v1

Effets sur la descendance de la lapine juvénile d'un régime hyperlipidique hypercholestérolémique

Pascale Chavatte-Palmer , Marie Baron , Jean Luc Servely , Patrice Laigre , Laurence Fortun-Lamothe
Journées de Restitution des projets financés sur credits incitatifs du Département PHASE, Sep 2006, Tours, France. pp.93
Communication dans un congrès hal-02817367v1

Developmental effects of cholesterol-enriched hyperlipidic diets in rabbits.

Pascale Chavatte-Palmer , Patrice Laigre , Michèle Dahirel , Olivier Picone , Laurence Lamothe
New Inroads to Child Health (NICHe) Conference 2009., May 2009, Göteberg, Sweden. n.p., 2009
Poster de conférence hal-02819404v1