Patricia Lemarchand

Identifiants chercheurs

IdHAL :

patricia-lemarchand

ORCID :

0000-0002-5330-2008

IdRef :

09290419X

ResearcherID :

http://www.researcherid.com/rid/C-3247-2011

Présentation

Patricia Lemarchand est pneumologue et professeure à Nantes Université. Ses recherches portent sur les cellules souches et leurs applications médicales. Elle enseigne aux étudiant·es en médecine la biologie cellulaire, ainsi que les différences hommes/femmes en médecine en lien avec le sexe et le genre.

Publications

Article dans une revue (42)

Rethinking medical education through systems biology to address complexity Laurent David,Pierre-Antoine Gourraud,Guillaume Lamirault,Patricia Lemarchand npj Systems Biology and Applications, 2026, 12 (1), pp.12. ⟨10.1038/s41540-025-00636-5⟩ Article dans une revue inserm-05509929v1
Increased delay to lung transplantation for women candidates: gender-based disparity matters in the lung transplant trajectory Adrien Tissot,Anne-Sophie Coatanea,Olivia Rousseau,Antoine Roux,Benjamin Coiffardet al. ERJ Open Research, 2025, pp.00623-2024. ⟨10.1183/23120541.00623-2024⟩ Article dans une revue inserm-04880240v1
Understanding sex and gender disparities in COVID-19 mortality: a narrative review beyond biology Patricia Lemarchand,Madeleine Pape,Joëlle Schwarz Biology of Sex Differences, 2025, 16 (1), pp.76. ⟨10.1186/s13293-025-00762-z⟩ Article dans une revue inserm-05509953v1
Questioning the Relevance of Sex Categories implemented in Medical Decision Support Systems - The Example of Pulmonary Function Patricia Lemarchand,Dorian Hassoun,Pascale Kuntz ESSACHESS – Journal for Communication Studies, 2024, 17 (1(33)), pp.205-229. ⟨10.21409/8253-X893⟩ Article dans une revue inserm-04653946v1
Microvascular obstruction identifies a subgroup of patients who benefit from stem cell therapy following ST-elevation myocardial infarction Sarah Davidson,Jerome Roncalli,Daniel Surder,Roberto Corti,Atul Chughet al. American Heart Journal, 2023, 259, pp.79-86. ⟨10.1016/j.ahj.2023.02.004⟩ Article dans une revue inserm-04205291v1
Generation of human induced pluripotent stem cell lines from four unrelated healthy control donors carrying European genetic background Aurore Girardeau,Diane Atticus,Robin Canac,Bastien Cimarosti,Amandine Caillaudet al. Stem Cell Research, 2022, 59, pp.102647. ⟨10.1016/j.scr.2021.102647⟩ Article dans une revue hal-04590823v1
Deciphering Transcriptional Networks during Human Cardiac Development Robin Canac,Bastien Cimarosti,Aurore Girardeau,Virginie Forest,Pierre Olchesquiet al. Cells, 2022, 11 (23), pp.3915. ⟨10.3390/cells11233915⟩ Article dans une revue inserm-04136798v1
Evaluation of the Post-COVID-19 Functional Status (PCFS) Scale in a cohort of patients recovering from hypoxemic SARS-CoV-2 pneumonia. Naïla Benkalfate,Emmanuel Eschapasse,Thomas Georges,Camille Leblanc,Stéphanie Dirouet al. BMJ open respiratory research, 2022, 9 (1), pp.e001136. ⟨10.1136/bmjresp-2021-001136⟩ Article dans une revue hal-03618379v1
Generation of three human induced pluripotent stem cell lines with IRX5 knockout and knockin genetic editions using CRISPR-Cas9 system Robin Canac,Amandine Caillaud,Bastien Cimarosti,Aurore Girardeau,Hanan Hamamyet al. Stem Cell Research, 2022, 58, pp.102627. ⟨10.1016/j.scr.2021.102627⟩ Article dans une revue hal-03585527v1
Generation of human induced pluripotent stem cell lines from three patients affected by Catecholaminergic Polymorphic ventricular tachycardia (CPVT) carrying heterozygous mutations in RYR2 gene Bastien Cimarosti,Robin Canac,Stephan de Waard,Aurore Girardeau,Anne Gaignerieet al. Stem Cell Research, 2022, 60, pp.102688. ⟨10.1016/j.scr.2022.102688⟩ Article dans une revue hal-04590843v1
Generation of human induced pluripotent stem cell lines from two patients affected by catecholamine-induced QT prolongation (CIQTP) Bastien Cimarosti,Robin Canac,Aurore Girardeau,Marine Arnaud,Quentin Francheteauet al. Stem Cell Research, 2022, 59, pp.102649. ⟨10.1016/j.scr.2021.102649⟩ Article dans une revue hal-04590780v1
Human model of IRX5 mutations reveals key role for this transcription factor in ventricular conduction Zeina Al Sayed,Robin Canac,Bastien Cimarosti,Carine Bonnard,Jean-Baptiste Gourraudet al. Cardiovascular Research, 2021, 117 (9), pp.2092-2107. ⟨10.1093/cvr/cvaa259⟩ Article dans une revue inserm-02934863v2
A consistent arrhythmogenic trait in Brugada syndrome cellular phenotype Zeina Al Sayed,Mariam Jouni,Jean-Baptiste Gourraud,Nadjet Belbachir,Julien Barcet al. Clinical and Translational Medicine, 2021, 11 (6), pp.e413. ⟨10.1002/ctm2.413⟩ Article dans une revue inserm-04136802v2
Functional Impact of BeKm-1, a High-Affinity hERG Blocker, on Cardiomyocytes Derived from Human-Induced Pluripotent Stem Cells Stephan de Waard,Jérôme Montnach,Barbara Ribeiro,Sébastien Nicolas,Virginie Forestet al. International Journal of Molecular Sciences, 2020, 21 (19), pp.7167. ⟨10.3390/ijms21197167⟩ Article dans une revue hal-02951542v1
Maurocalcin and its analogue MCaE12A facilitate Ca2+ mobilization in cardiomyocytes Stephan de Waard,Jérôme Montnach,Charly Cortinovis,Olfa Chkir,Morteza Erfanianet al. Biochemical Journal, 2020, 477 (20), pp.3985-3999. ⟨10.1042/BCJ20200206⟩ Article dans une revue inserm-02968252v1
Deconditioning, fatigue and impaired quality of life in long-term survivors after allogeneic hematopoietic stem cell transplantation Stéphanie Dirou,Arnaud Chambellan,Patrice Chevallier,Patrick Germaud,Guillaume Lamiraultet al. Bone Marrow Transplantation, 2017, Epub ahead of print. ⟨10.1038/s41409-017-0057-5⟩ Article dans une revue inserm-01684314v1
Sustained quality of life improvement after intracoronary injection of autologous bone marrow cells in the setting of acute myocardial infarction: results from the BONAMI trial Guillaume Lamirault,Elodie de Bock,Véronique Sébille,Béatrice Delasalle,Jérôme Roncalliet al. Quality of Life Research, 2017, 26 (1), pp.121-125. ⟨10.1007/s11136-016-1366-7⟩ Article dans une revue inserm-01350712v1
Intramyocardial transplantation of mesenchymal stromal cells for chronic myocardial ischemia and impaired left ventricular function: Results of the MESAMI 1 pilot trial Damien Guijarro,M Lebrin,Olivier Lairez,Philippe Bourin,Nicolas Piriouet al. International Journal of Cardiology, 2016, ⟨10.1016/j.ijcard.2016.02.016⟩ Article dans une revue inserm-01269644v1
Mesenchymal Stem Cells Induce Suppressive Macrophages through Phagocytosis in a Mouse Model of Asthma Faouzi Braza,Stéphanie Dirou,Virginie Forest,Vincent Sauzeau,Dorian Hassounet al. STEM CELLS, 2016, ⟨10.1002/stem.2344⟩ Article dans une revue inserm-01277384v1
HIV-Tat induces a decrease in I Kr and I Ks via reduction in phosphatidylinositol-(4,5)-bisphosphate availability Zeineb Es-Salah-Lamoureux,Mariam Jouni,Nadjet Belbachir,Zeina Reda,Al Sayedet al. Journal of Molecular and Cellular Cardiology, 2016, [Epub ahead of print]. ⟨10.1016/j.yjmcc.2016.08.022⟩ Article dans une revue inserm-01360585v1
Toward Personalized Medicine: Using Cardiomyocytes Differentiated From Urine-Derived Pluripotent Stem Cells to Recapitulate Electrophysiological Characteristics of Type 2 Long QT Syndrome Mariam Jouni,Karim Si-Tayeb,Zeineb Es-Salah-Lamoureux,Xenia Latypova,Benoite Champonet al. Journal of the American Heart Association, 2015, pp.e002159. ⟨10.1161/JAHA.115.002159⟩ Article dans une revue inserm-01199430v1
Impact of pre-transplant diffusion lung capacity for nitric oxide (DLNO) and of DLNO/pre-transplant diffusion lung capacity for carbon monoxide (DLNO/DLCO) ratio on pulmonary outcomes in adults receiving allogeneic stem cell transplantation for hematological diseases Amandine Le Bourgeois,Florent Malard,Patrice Chevallier,Gaxuxa Urbistandoy,Thierry Guillaumeet al. Bone Marrow Transplantation, 2015, 51 (4), pp.589 - 592. ⟨10.1038/bmt.2015.284⟩ Article dans une revue inserm-01636141v1
Meta-Analysis of Cell-based CaRdiac stUdiEs (ACCRUE) in patients with acute myocardial infarction based on individual patient data. Mariann Gyöngyösi,Wojciech Wojakowski,Patricia Lemarchand,Ketil Lunde,Michal Tenderaet al. Circulation Research, 2015, 116 (8), pp.1346-60. ⟨10.1161/CIRCRESAHA.116.304346⟩ Article dans une revue inserm-01261631v2
Predictors of ventricular remodelling in patients with reperfused acute myocardial infarction and left ventricular dysfunction candidates for bone marrow cell therapy: insights from the BONAMI trial Alain Manrique,Patricia Lemarchand,Béatrice Delasalle,Olivier Lairez,Catherine Sportouchet al. European Journal of Nuclear Medicine and Molecular Imaging, 2015, ⟨10.1007/s00259-015-3279-z⟩ Article dans une revue inserm-01261620v1
Urine-sample-derived human induced pluripotent stem cells as a model to study PCSK9-mediated autosomal dominant hypercholesterolemia Karim Si-Tayeb,Salam Idriss,Benoite Champon,Amandine Caillaud,Matthieu Pichelinet al. Disease Models & Mechanisms, 2015, ⟨10.1242/dmm.022277⟩ Article dans une revue hal-01233240v1
Stable long-term pulmonary function after fludarabine, antithymocyte globulin and i.v. BU for reduced-intensity conditioning allogeneic SCT. Stéphanie Dirou,Florent Malard,Arnaud Chambellan,Patrice Chevallier,Patrick Germaudet al. Bone Marrow Transplantation, 2014, 49 (5), pp.622-7. ⟨10.1038/bmt.2014.15⟩ Article dans une revue inserm-00955626v1
Impact of intracoronary bone marrow cell therapy on left ventricular function in the setting of ST-segment elevation myocardial infarction: a collaborative meta-analysis. Ronak Delewi,Alexander Hirsch,Jan G. Tijssen,Volker Schächinger,Wojciech Wojakowskiet al. European Heart Journal, 2014, 35 (15), pp.989-98. ⟨10.1093/eurheartj/eht372⟩ Article dans une revue inserm-00907022v1
Difference in mobilization of progenitor cells after myocardial infarction in smoking versus non-smoking patients: insights from the BONAMI trial. Guillaume Lamirault,Sophie Susen,Virginie Forest,Caroline Hemont,Angelo Pariniet al. Stem Cell Research and Therapy, 2013, 4 (6), pp.152. ⟨10.1186/scrt382⟩ Article dans une revue inserm-00932365v1
Intramyocardial delivery of mesenchymal stem cell-seeded hydrogel preserves cardiac function and attenuates ventricular remodeling after myocardial infarction. Eva Mathieu,Guillaume Lamirault,Claire Toquet,Pierre Lhommet,Emilie Rederstorffet al. PLoS ONE, 2012, 7 (12), pp.e51991. ⟨10.1371/journal.pone.0051991⟩ Article dans une revue inserm-00770250v1
Autologous bone marrow cells and ischemic cardiomyopathy. Jérôme Roncalli,Patricia Lemarchand Future Cardiology, 2011, 7 (5), pp.603-7. ⟨10.2217/fca.11.46⟩ Article dans une revue inserm-00642809v1
Signaling by the Matrix Proteoglycan Decorin Controls Inflammation and Cancer Through PDCD4 and MicroRNA-21. Rosetta Merline,Kristin Moreth,Janet Beckmann,Madalina V. Nastase,Jinyang Zeng-Brouwerset al. Science Signaling, 2011, 4 (199), pp.ra75. ⟨10.1126/scisignal.2001868⟩ Article dans une revue inserm-00642810v1
Intracoronary autologous mononucleated bone marrow cell infusion for acute myocardial infarction: results of the randomized multicenter BONAMI trial. Jérôme Roncalli,Frédéric Mouquet,Christophe Piot,Jean-Noël Trochu,Philippe Le Corvoisieret al. European Heart Journal, 2011, 32 (14), pp.1748-1757. ⟨10.1093/eurheartj/ehq455⟩ Article dans une revue inserm-00543644v1
Carotid and femoral atherosclerotic plaques show different morphology. Fanny Herisson,Marie-Françoise Heymann,Maud Chétiveaux,Céline Charrier,Séverine Battagliaet al. Atherosclerosis, 2011, 216 (2), pp.348-54. ⟨10.1016/j.atherosclerosis.2011.02.004⟩ Article dans une revue inserm-00642808v1
Cell distribution after intracoronary bone marrow stem cell delivery in damaged and undamaged myocardium: implications for clinical trials. Virginie Forest,Ashok Tirouvanziam,Christian Perigaud,Sarah Fernandes,Marion Fusellieret al. Stem Cell Research and Therapy, 2010, 1 (1), pp.4. ⟨10.1186/scrt4⟩ Article dans une revue inserm-00663767v1
Developing cell therapy techniques for respiratory disease: intratracheal delivery of genetically engineered stem cells in a murine model of airway injury. Anne-Laure Leblond,Patrice Naud,Virginie F. Forest,Clothilde Gourden,Christine Saganet al. Human Gene Therapy, 2009, 20 (11), pp.1329-43. ⟨10.1089/hum.2009.035⟩ Article dans une revue inserm-00407987v1
Cardiac cell therapy: overexpression of connexin43 in skeletal myoblasts and prevention of ventricular arrhythmias. Sarah Fernandes,Harold V.M. van Rijen,Virginie F. Forest,Stéphane Evain,Anne-Laure Leblondet al. Journal of Cellular and Molecular Medicine, 2009, 13 (9B), pp.3703-12. ⟨10.1111/j.1582-4934.2009.00740.x⟩ Article dans une revue inserm-00369695v1
Autologous myoblast transplantation after myocardial infarction increases the inducibility of ventricular arrhythmias Sarah Fernandes,Jean-Christophe Amirault,Gilles Lande,Jean-Michel Nguyen,Virginie Forestet al. Cardiovascular Research, 2006, 69 (2), pp.348 - 358. ⟨10.1016/j.cardiores.2005.10.003⟩ Article dans une revue inserm-01707095v1
In vivo selective and distant killing of cancer cells using adenovirus-mediated decorin gene transfer José Guilherme Guilherme Tralhão,Liliana Schaefer,Miroslava Micegova,César Evaristo,Elke Schönherret al. FASEB Journal, 2003, 17 (3), pp.464 - 466. ⟨10.1096/fj.02-0534fje⟩ Article dans une revue inserm-01707109v1
Characterization of the Role of AMP-Activated Protein Kinase in the Regulation of Glucose-Activated Gene Expression Using Constitutively Active and Dominant Negative Forms of the Kinase Angela Woods,Dalila D. Azzout-Marniche,Marc Foretz,Silvie Stein,Patricia Lemarchandet al. Molecular and Cellular Biology, 2000, 20 (18), pp.6704-6711. ⟨10.1128/mcb.20.18.6704-6711.2000⟩ Article dans une revue hal-02546620v1
Characterization of the role of AMP-activated protein kinase in the regulation of glucose-activated gene expression using constitutively active and dominant negative forms of the kinase. A Woods,Dalila D. Azzout-Marniche,M Foretz,S C Stein,P Lemarchandet al. Molecular and Cellular Biology, 2000, pp.6704-11 Article dans une revue hal-01611458v1
ADD1/SREBP-1c Is Required in the Activation of Hepatic Lipogenic Gene Expression by Glucose Marc Foretz,Corinne Pacot,Isabelle Dugail,Patricia Lemarchand,Colette Guichardet al. Molecular and Cellular Biology, 1999, 19 (5), pp.3760-3768. ⟨10.1128/mcb.19.5.3760⟩ Article dans une revue hal-02350031v1
In vivo gene transfer and expression in normal uninjured blood vessels using replication-deficient recombinant adenovirus vectors. Patricia Lemarchand,M Jones,I Yamada,R Crystal Circulation Research, 1993, 72 (5), pp.1132-1138. ⟨10.1161/01.RES.72.5.1132⟩ Article dans une revue inserm-05117017v1

Communication dans un congrès (1)

17° Entretiens de la sauvegarde - Table ronde : La vérification du passif Mathilde Naïda Alice Dols-Magneville,Sophie Atsarias-dumas,Pierre Charlier,Patricia Lemarchand 17° Entretiens de la sauvegarde - IFPPC, IFPPC, Jan 2022, Paris (en virtuel), France Communication dans un congrès hal-04929320v1

Poster de conférence (1)

Construire un intérêt professionnel pour la recherche et choisir la voie Hospitalo-Universitaire (HU): un chemin sinueux chez les étudiant-ES. Valentine Bour,Anne Congard,Elisa Sarda,Jean-Michel Galharret,Fleur Cohen-Aubartet al. 15ème Congrès International de Psychologie Sociale., Jul 2024, Bruxelles, Belgique Poster de conférence hal-04949405v1

Chapitre d'ouvrage (2)

Introduction. Qu’est-ce qu’une femme ? Question singulière, enjeux pluriels Patricia Lemarchand,Muriel Salle Qu'est-ce qu'une femme ?, Éditions Matériologiques, pp.3-15, 2023, 978-2-37361-409-1. ⟨10.3917/edmat.lemar.2023.01.0005⟩ Chapitre d'ouvrage inserm-04136765v1
Chapitre 2. La catégorie homme/femme à l’épreuve de la recherche biomédicale Patricia Lemarchand Qu'est-ce qu'une femme ?, Éditions Matériologiques, pp.23-67, 2023, 978-2-37361-409-1. ⟨10.3917/edmat.lemar.2023.01.0025⟩ Chapitre d'ouvrage inserm-04136758v1

Notice d’encyclopédie ou de dictionnaire (1)

Biology and medicine (beyond a biological concept of sex in health) Patricia Lemarchand,Joelle Schwarz,Carole Clair,Madeleine Pape Dictionnaire du genre en traduction / Dictionary of Gender in Translation / Diccionario del género en traducción., 2024 Notice d’encyclopédie ou de dictionnaire inserm-05092597v1

Pré-publication, Document de travail (1)

Deciphering transcriptional networks during human cardiac development Robin Canac,Bastien Cimarosti,Aurore Girardeau,Virginie Forest,Pierre Olchesquiet al. 2022 Pré-publication, Document de travail hal-03796013v1