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Patrick Baril

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Targeting TGF-β1/miR-21 Pathway in Keratinocytes Reveals Protective Effects of Silymarin on Imiquimod-Induced Psoriasis Mouse Model

Elodie Henriet , Florence Abdallah , Yoan Laurent , Cyril Guimpied , Emily Clement
JID Innovations, 2023, 3 (3), pp.100175. ⟨10.1016/j.xjidi.2022.100175⟩
Journal articles hal-04220607v1
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miR-21-3p/IL-22 axes are major drivers of psoriasis pathogenesis by modulating keratinocytes proliferationsurvival balance and inflammatory response

Florence Abdallah , Elodie Henriet , Amandine Suet , Ali Arar , Rudy Clemençon
Cells, 2021, 10 (10), pp.2547. ⟨10.3390/cells10102547⟩
Journal articles hal-03434971v1
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LentiRILES, a miRNA-ON Sensor System for Monitoring the Functionality of miRNA in Cancer Biology and Therapy

Viorel Simion , Claire Loussouarn , Yoan Laurent , Loris Roncali , David Gosset
RNA Biology/RNA Biol., 2021, Online ahead of print. ⟨10.1080/15476286.2021.1978202⟩
Journal articles inserm-03374619v1
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Protective Role of Spirulina platensis against Bifenthrin-Induced Reprotoxicity in Adult Male Mice by Reversing Expression of Altered Histological, Biochemical, and Molecular Markers Including MicroRNAs

Mohamed Barkallah , Ahlem Ben Slima , Fatma Elleuch , Imen Fendri , Chantal Pichon
Biomolecules, 2020, 10 (5), pp.753. ⟨10.3390/biom10050753⟩
Journal articles hal-02901693v1
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Intracellular trafficking and functional monitoring of miRNA delivery in glioblastoma using lipopolyplexes and the miRNA-ON RILES reporter system

Viorel Simion , Elodie Henriet , Viktorija Juric , Ruth Aquino , Claire Loussouarn
Journal of Controlled Release, 2020, 327, pp.429-443. ⟨10.1016/j.jconrel.2020.08.028⟩
Journal articles hal-02959393v1
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Asian hornet Vespa velutina nigrithorax venom: Evaluation and identification of the bioactive compound responsible for human keratinocyte protection against oxidative stress

Nhi Thao Le , David D. da Silva , Cyril Colas , Éric Darrouzet , Patrick Baril
Toxicon, 2020, 176, pp.1-9. ⟨10.1016/j.toxicon.2020.01.001⟩
Journal articles hal-02794316v1

Development of an LC-MS multivariate nontargeted methodology for differential analysis of the peptide profile of Asian hornet venom (Vespa velutina nigrithorax): application to the investigation of the impact of collection period variation

Thao Nhi Le , David D. da Silva , Cyril Colas , Éric Darrouzet , Patrick Baril
Analytical and Bioanalytical Chemistry, 2020, 412 (6), pp.1419-1430. ⟨10.1007/s00216-019-02372-2⟩
Journal articles hal-02794337v1
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Deciphering the Biological Activities of Dunaliella sp. Aqueous Extract from Stressed Conditions on Breast Cancer: from in Vitro to in Vivo Investigations

Fatma Elleuch , Patrick Baril , Mohamed Barkallah , Federico Perche , Slim Abdelkafi
International Journal of Molecular Sciences, 2020, 21 (5), pp.1719. ⟨10.3390/ijms21051719⟩
Journal articles hal-02553031v1
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MicroRNA-based Drugs for Brain Tumours

Shubaash Anthiya , Audrey Griveau , Claire Loussouarn , Patrick Baril , Martin Garnett
Trends in Cancer, 2018, 4 (3), pp.222-238. ⟨10.1016/j.trecan.2017.12.008⟩
Journal articles inserm-01691531v2
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Dendritic Cell Targeting mRNA Lipopolyplexes Combine Strong Antitumor T-Cell Immunity with Improved Inflammatory Safety

Kevin van Der Jeught , Stefaan de Koker , Lukasz Bialkowski , Carlo Heirman , Patrick Tjok Joe
ACS Nano, 2018, 12 (10), pp.9815-9829. ⟨10.1021/acsnano.8b00966⟩
Journal articles hal-01889829v1

Positive radionuclide imaging of miRNA expression using RILES and the human sodium iodide symporter as reporter gene is feasible and supports a protective role of miRNA-23a in response to muscular atrophy

Viorel Simion , Julien Sobilo , Rudy Clemoncon , Sharuja Natkunarajah , Safia Ezzine
PLoS ONE, 2017, 12 (5), pp.e0177492. ⟨10.1371/journal.pone.0177492⟩
Journal articles hal-01618769v1

Production of DNA minicircles less than 250 base pairs through a novel concentrated DNA circularization assay enabling minicircle design with NF-κB inhibition activity

Thomas Thibault , Jéril Degrouard , Patrick Baril , Chantal Pichon , Patrick Midoux
Nucleic Acids Research, 2017, 45 (5), pp.e26 - e26. ⟨10.1093/nar/gkw1034⟩
Journal articles hal-01618796v1

Réguler l’expression d’un transgène thérapeutique par un régime alimentaire carencé en un acide aminé indispensable. Tuning transgene expression with an artificial diet: a compelling resource in gene therapy.

Alain Bruhat , Cedric Chaveroux , Valerie Carraro , Céline Jousse , Julien Averous
Médecine/Sciences, 2017, 33 (2), pp.136-139. ⟨10.1051/medsci/20173302007⟩
Journal articles hal-01595228v1

MicroRNAs in Neurocognitive Dysfunctions: New Molecular Targets for Pharmacological Treatments?

Wissem Deraredj Nadim , Simion Viorel , Hélène Bénédetti , Chantal Pichon , Patrick Baril
Current Neuropharmacology, 2017, 15 (2), pp.260 - 275. ⟨10.2174/1570159X14666160709001441⟩
Journal articles hal-01618199v1

Pharmacomodulation of microRNA Expression in Neurocognitive Diseases: Obstacles and Future Opportunities

Viorel Simion , Wissem Deraredj Nadim , Hélène Bénédetti , Chantal Pichon , Séverine Morisset-Lopez
Current Neuropharmacology, 2017, 15 (2), pp.276 - 290. ⟨10.2174/1570159X14666160630210422⟩
Journal articles hal-01618771v1

Regulating the expression of therapeutic transgenes by controlled intake of dietary essential amino acids

Cedric Chaveroux , Alain Bruhat , Valerie Carraro , Céline Jousse , Julien Averous
Nature Biotechnology, 2016, 34, pp.746-751. ⟨10.1038/nbt.3582⟩
Journal articles hal-01594469v1

The promise of gene therapy for pancreatic cancer

Georges Vassaux , Assia Angelova , Patrick Baril , Patrick Midoux , Jean Rommelaere
Human Gene Therapy, 2016, 27 (2), pp.127 - 133. ⟨10.1089/hum.2015.141⟩
Journal articles hal-01407834v1

Identification of a new oat β-amylase by functional proteomics

Nihed Ben Halima , Bassem Khemakhem , Imen Fendri , Hiroyuki Ogata , Patrick Baril
Biochimica et Biophysica Acta Proteins and Proteomics, 2016, 1864 (1), pp.52 - 61. ⟨10.1016/j.bbapap.2015.10.001⟩
Journal articles hal-01405835v1

Positive Bioluminescence Imaging of MicroRNA Expression in Small Animal Models Using an Engineered Genetic-Switch Expression System, RILES.

Patrick Baril , Chantal Pichon
Methods in Molecular Biology, 2016, 1372, pp.193-208
Journal articles hal-01405832v1

Bioreducible poly(2-ethyl-2-oxazoline)–PLA–PEI-SS triblock copolymer micelles for co-delivery of DNA minicircles and Doxorubicin

Vítor Gaspar , Elisabete C. Costa , Duarte de Melo-Diogo , Frédéric Foucher , João A. Queiroz
Journal of Controlled Release, 2015, 213 (7), pp.175 - 191. ⟨10.1016/j.jconrel.2015.07.011⟩
Journal articles hal-01657388v1

Optimised amylases extraction from oat seeds and its impact on bread properties.

Nihed Ben Halima , Maha Borchani , Imen Fendri , Bassem Khemakhem , David Gosset
International Journal of Biological Macromolecules, 2015, 72, pp.1213-1221. ⟨10.1016/j.ijbiomac.2014.10.018⟩
Journal articles hal-01170470v1

Enhanced Achilles tendon healing by fibromodulin gene transfer

Anthony Delalande , Marie-Pierre Gosselin , Arnaud Suwalski , William Guilmain , Chloé Leduc
Nanomedicine: Nanotechnology, Biology and Medicine, 2015, 11 (7), pp.1735 - 1744. ⟨10.1016/j.nano.2015.05.004⟩
Journal articles hal-01537597v1

Monitoring the Spatiotemporal Activities of miRNAs in Small Animal Models Using Molecular Imaging Modalities

Patrick Baril , Safia Ezzine , Chantal Pichon
International Journal of Molecular Sciences, 2015, 16 (3), pp.4947-4972. ⟨10.3390/ijms16034947⟩
Journal articles hal-01170451v1

RILES, a novel method for temporal analysis of the in vivo regulation of miRNA expression.

Safia Ezzine , Georges Vassaux , Bruno Pitard , Benoit Barteau , Jean-Marc Malinge
Nucleic Acids Research, 2013, epub ahead of print. ⟨10.1093/nar/gkt797⟩
Journal articles hal-00874881v1

Differential biodistribution of oncolytic poxvirus administered systemically in an autochthonous model of hepatocellular carcinoma.

Patrick Baril , Yann Touchefeu , Jeannette Cany , Yan Cherel , Steve H Thorne
The Journal of Gene Medicine, 2011, 13 (12), pp.692-701. ⟨10.1002/jgm.1624⟩
Journal articles hal-00720514v1

Visualization of gene expression in the live subject using the Na/I symporter as a reporter gene: applications in biotherapy

Patrick Baril , Pilar Martin-Duque , Georges Vassaux
British Journal of Pharmacology, 2010, 159 (4), pp.761-771. ⟨10.1111/j.1476-5381.2009.00412.x⟩
Journal articles hal-02086340v1

Assessment of the Na/I symporter as a reporter gene to visualize oncolytic adenovirus propagation in peritoneal tumours

Andrew Merron , Patrick Baril , Pilar Martin-Duque , Antonio de La Vieja , Lucile Tran
European Journal of Nuclear Medicine and Molecular Imaging, 2010, 37 (7), pp.1377-1385. ⟨10.1007/s00259-009-1379-3⟩
Journal articles hal-02086304v1

Targeted Radionuclide Therapy Using a Wnt-Targeted Replicating Adenovirus Encoding the Na/I Symporter

Inge Peerlinck , Andrew Merron , Patrick Baril , Sophie Conchon , Pilar Martin-Duque
Clinical Cancer Research, 2009, 15 (21), pp.6595-6601. ⟨10.1158/1078-0432.CCR-09-0262⟩
Journal articles hal-02086310v1

Cancer-Specific Transgene Expression Mediated by Systemic Injection of Nanoparticles

Edward Chisholm , Georges Vassaux , Pilar Martin-Duque , Raphaël Chèvre , Olivier Lambert
Cancer Research, 2009, 69 (6), pp.2655-2662. ⟨10.1158/0008-5472.CAN-08-2657⟩
Journal articles hal-02086345v1

Development of an Escherichia coli Expressing Listeriolysin-O Vaccine Against Wilms Tumor Gene 1-expressing Tumors

Ming-Shen Dai , Josianne Nitcheu-Tefit , Sally Alcock , Francisco Ramirez-Jimenez , Tsu-Yi Chao
Journal of Immunotherapy, 2009, 32 (8), pp.845-855. ⟨10.1097/CJI.0b013e3181aee259⟩
Journal articles hal-02086312v1

Uveal vs. cutaneous melanoma. Origins and causes of the differences.

Carolina Belmar-Lopez , Pablo Mancheno-Corvo , Maria Antonia Saornil , Patrick Baril , Georges Vassaux
Clinical and Translational Oncology, 2008, 10 (3), pp.137-42
Journal articles hal-02086350v1

Genome-wide DNA copy number analysis in pancreatic cancer using high-density single nucleotide polymorphism arrays

T Harada , C. Chelala , B Bhakta , T Chaplin , K Caulee
Oncogene, 2008, 27 (13), pp.1951-1960. ⟨10.1038/sj.onc.1210832⟩
Journal articles hal-02086360v1

Identification of genetic alterations in pancreatic cancer by the combined use of tissue microdissection and array-based comparative genomic hybridisation

T Harada , P Baril , R Gangeswaran , G Kelly , C. Chelala
British Journal of Cancer, 2007, 96 (2), pp.373-382. ⟨10.1038/sj.bjc.6603563⟩
Journal articles hal-02086372v1

S100A4 Contributes to the Suppression of BNIP3 Expression, Chemoresistance, and Inhibition of Apoptosis in Pancreatic Cancer

Patrick Mahon , Patrick Baril , Vipul Bhakta , Claude Chelala , Krishna Caulee
Cancer Research, 2007, 67 (14), pp.6786-6795. ⟨10.1158/0008-5472.CAN-07-0440⟩
Journal articles hal-02086365v1

Periostin promotes invasiveness and resistance of pancreatic cancer cells to hypoxia-induced cell death: role of the β4 integrin and the PI3k pathway

P Baril , R Gangeswaran , P.C Mahon , K Caulee , H.M Kocher
Oncogene, 2007, 26 (14), pp.2082-2094. ⟨10.1038/sj.onc.1210009⟩
Journal articles hal-02128711v1

mda-9 /Syntenin: A Positive Regulator of Melanoma Metastasis

H Boukerche , Zao-Zhong Su , Paul Fisher , Luni Emdad , Habib Su
Cancer Research, 2005, 65 (23), pp.10901-10911. ⟨10.1158/0008-5472.CAN-05-1614⟩
Journal articles hal-02128733v1

Blocking a novel 55 kDa melanoma-associated cell surface antigen inhibits the development of spontaneous metastases and interactions with frozen lung section

Patrick Baril , Mimoun Nejjari , Jean-Yves Scoazek , Habib Boukerche
International Journal of Cancer, 2002, 99 (3), pp.315-322. ⟨10.1002/ijc.10324⟩
Journal articles hal-02128747v1

Identification and cloning of an 85-kDa protein homologous to RING3 that is upregulated in proliferating endothelial cells.

E Belaiba , P Baril , Y. Chebloune , E. Tabone , H. Boukerche
European Journal of Biochemistry, 2001, 268 (16), pp.4398-407
Journal articles hal-02128755v1

Identification and cloning of an 85-kDa protein homologous to RING3 that is upregulated in proliferating endothelial cells

Rachida-Siham Belaiba , Patrick Baril , Yahia Chebloune , Eric Tabone , Habib Boukerche
European Journal of Biochemistry, 2001, 268 (16), pp.4398-4407. ⟨10.1046/j.1432-1327.2001.02355.x⟩
Journal articles hal-02965427v1

A new Mr 55,000 surface protein implicated in melanoma progression: association with a metastatic phenotype.

H Boukerche , Patrick Baril , E. Tabone , F. Berard , K Sanhadji
Cancer Research, 2000, 60 (20), pp.5848-56
Journal articles hal-02128813v1