Patrick MEFFRE Professeur des universitésFull professor

Identifiants chercheurs

IdHAL :

patrick-meffre

ORCID :

0000-0002-6189-9860

IdRef :

177072482

Présentation

Patrick Meffre est né à Marseille, en France, en 1964. Après des études d'ingénieur à l'École nationale supérieure de chimie de Paris (ENSCP, Chimie ParisTech-PSL, membre de l'Université Paris-Sciences et Lettres, PSL, France), il a obtenu son doctorat à l'Université Pierre et Marie Curie (Paris) en 1991 sous la direction du professeur F. Le Goffic. Après un stage postdoctoral auprès du professeur S. Hanessian (Université de Montréal, Québec, Canada), il a été nommé maître de conférences à l'École nationale supérieure de chimie de Paris en 1993. Depuis 2004, il est professeur titulaire à l'Université de Nîmes (France).

Ses centres d'intérêt actuels concernent :

-L'extraction et l'identification de composés naturels d'origine végétale, notamment les composés organiques volatils (COV), et leur activité biologique.

-La synthèse de composés biologiquement actifs, chiraux ou non, (agents antibactériens, adjuvants), d'acides aminés inhabituels, de synthons chiraux dérivés d'acides aminés naturels et l'étude de leur activité biologique.

-L'utilisation de plantes épiphytes (genre Tillandsia) comme source naturelle de composés biologiquement actifs ou comme biomoniteurs de la pollution atmosphérique.

Patrick Meffre est rédacteur en chef adjoint de la revue Amino Acids (Springer)https://www.springer.com/journal/726

Publications

Article dans une revue (58)

Biomonitoring of elements airborne pollution in European Mediterranean region by two Tillandsia species Alexandre Gonzalez,Zohra Benfodda,David Bénimélis,Damien Bourgeois,Jean-Xavier Fontaineet al. Atmospheric Pollution Research, 2025, 16 (8), pp.102576. ⟨10.1016/j.apr.2025.102576⟩ Article dans une revue hal-05075353v1
Survey on the Traditional Use of Medicinal Herbs in Haiti: A Study on Knowledge, Practices, and Efficacy Prevention Valendy Thesnor,Yvens Cheremond,Muriel Sylvestre,Patrick Meffre,Gerardo Cebrián-Torrejónet al. Plants, 2024, 13 (17), pp.2383. ⟨10.3390/plants13172383⟩ Article dans une revue hal-04689090v1
Synergistic effect of tryptamine-urea derivatives to overcome the chromosomally-mediated colistin resistance in Klebsiella pneumoniae Chaimae Majdi,Jean Dessolin,David Bénimélis,Catherine Dunyach-Rémy,Alix Pantelet al. Bioorganic and Medicinal Chemistry, 2024, 100, pp.117604. ⟨10.1016/j.bmc.2024.117604⟩ Article dans une revue hal-04419733v1
Recent advances in the development of bacterial response regulators inhibitors as antibacterial and/or antibiotic adjuvant agent: A new approach to combat bacterial resistance Chaimae Majdi,Patrick Meffre,Zohra Benfodda Bioorganic Chemistry, 2024, 150, pp.107606. ⟨10.1016/j.bioorg.2024.107606⟩ Article dans une revue hal-04675217v1
Determination of the maximum bioaccumulation capacity of various metals in leaves of two Tillandsia species Alexandre Gonzalez,Zohra Benfodda,David Bénimélis,Damien Bourgeois,Damien Herfurthet al. Environmental Science and Pollution Research, In press, ⟨10.1007/s11356-024-33183-3⟩ Article dans une revue hal-04535649v1
Volatile Organic Compounds Emitted by Flowers: Ecological Roles, Production by Plants, Extraction, and Identification Mame-Marietou Lo,Zohra Benfodda,Roland Molinié,Patrick Meffre Plants, 2024, 13 (3), pp.417. ⟨10.3390/plants13030417⟩ Article dans une revue hal-04430391v1
Synthesis of amino juglone derivatives with adjuvant activity against clinical isolated methicillin-resistant staphylococcus aureus strains Chaimae Majdi,Mohamed Seghir,Yehan Wegrich,Djilali Behilil,David Béniméliset al. Bioorganic Chemistry, 2024, 150, pp.107627. ⟨10.1016/j.bioorg.2024.107627⟩ Article dans une revue hal-04689127v1
Characterization of Alginates of Sargassum from the Archipelago of Guadeloupe Naika Marcin,Valendy Thesnor,Valentin Duvauchelle,Alejandro Ponce-Mora,Lucia Gimeno-Mallenchet al. Separations, 2024, 11 (8), pp.226. ⟨10.3390/separations11080226⟩ Article dans une revue hal-04689192v1
Investigation of PhoP Response Regulator inhibition to overcome resistance in Gram-negative clinical bacteria Chaimae Majdi,Valentin Duvauchelle,Mohamed Seghir,David Bénimélis,Catherine Dunyach-Rémyet al. International Journal of Antimicrobial Agents, 2024, 64 (4), pp.107298. ⟨10.1016/j.ijantimicag.2024.107298⟩ Article dans une revue hal-04674063v1
Phytochemical and Biological Study of Trophic Interaction between Pseudosphinx Tetrio L. Larvae and Allamanda Cathartica L. Linda Matignon,Mame Marietou Lo,Magneric Monpierre,Mauro Vicentini Correia,Drochss Pettry Valenciaet al. Plants, 2023, 12 (3), pp.520. ⟨10.3390/plants12030520⟩ Article dans une revue hal-04099507v1
β-cell–specific E2f1 deficiency impairs glucose homeostasis, β-cell identity, and insulin secretion Frédérik Oger,Cyril Bourouh,Marika Elsa Friano,Emilie Courty,Laure Rollandet al. Diabetes, 2023, 72 (8), pp.1112-1126. ⟨10.2337/db22-0604⟩ Article dans une revue hal-04200339v1
An overview on the antibacterial properties of juglone, naphthazarin, plumbagin and lawsone derivatives and their metal complexes Chaimae Majdi,Valentin Duvauchelle,Patrick Meffre,Zohra Benfodda Biomedicine and Pharmacotherapy, 2023, 162, pp.114690. ⟨10.1016/j.biopha.2023.114690⟩ Article dans une revue hal-04100606v1
Enzyme inhibitors for drug discovery Patrick Meffre,Zohra Benfodda,Sébastien Albrecht Amino Acids, 2023, 65, ⟨10.1007/s00726-023-03357-3⟩ Article dans une revue hal-04320815v1
Antibacterial Activity and Untargeted Metabolomics Profiling of Acalypha arvensis Poepp V. Thesnor,Roland Molinié,Ryland Giebelhaus,A. Paulina de la Mata Espinosa,James Harynuket al. Molecules, 2023, 28 (23), pp.7882. ⟨10.3390/molecules28237882⟩ Article dans une revue hal-04419754v1
Extraction and Identification of Volatile Organic Compounds in Scentless Flowers of 14 Tillandsia Species Using HS-SPME/GC-MS Alexandre Gonzalez,Zohra Benfodda,David Bénimélis,Jean-Xavier Fontaine,Roland Moliniéet al. Metabolites, 2022, 12 (9), pp.628. ⟨10.3390/metabo12070628⟩ Article dans une revue hal-03725030v1
The transcription factor E2F1 controls the GLP-1 receptor pathway in pancreatic β cells Cyril Bourouh,Emilie Courty,Laure Rolland,Gianni Pasquetti,Xavier Gromadaet al. Cell Reports, 2022, 40 (6), pp.111170. ⟨10.1016/j.celrep.2022.111170⟩ Article dans une revue hal-03810743v1
Green methodologies for the synthesis of 2-aminothiophene Valentin Duvauchelle,Patrick Meffre,Zohra Benfodda Environmental Chemistry Letters, 2022, ⟨10.1007/s10311-022-01482-1⟩ Article dans une revue hal-03798752v1
Recent contribution of medicinally active 2-aminothiophenes: a privileged scaffold for drug discovery Valentin Duvauchelle,Patrick Meffre,Zohra Benfodda European Journal of Medicinal Chemistry, 2022, ⟨10.1016/j.ejmech.2022.114502⟩ Article dans une revue hal-03798762v1
Catalyst-Free Site Selective Hydroxyalkylation of 5-Phenylthiophen-2-amine with α-Trifluoromethyl Ketones through Electrophilic Aromatic Substitution Valentin Duvauchelle,David Bénimélis,Patrick Meffre,Zohra Benfodda Molecules, 2022, 27 (3), pp.925. ⟨10.3390/molecules27030925⟩ Article dans une revue hal-03550954v1
Microwave-assisted synthesis of new environmentally friendly biodegradable and antibacterial heterocycles Miyanou Rosales-Hurtado,Valentin Duvauchelle,David Bénimélis,Maya Ogawa-Okada,Naofumi Yamamotoet al. Environmental Chemistry Letters, 2022, ⟨10.1007/s10311-022-01522-w⟩ Article dans une revue hal-03805578v1
Isolation and Identification of Flavones Responsible for the Antibacterial Activities of Tillandsia Bergeri Extracts. Mame-Marietou Lo,Zohra Benfodda,Catherine Dunyach-Rémy,David Bénimélis,Romain Roulardet al. ACS Omega, 2022, 7 (40), pp.35851--35862. ⟨10.1021/acsomega.2c04195⟩ Article dans une revue hal-03823329v1
Extraction and Identification of Volatile Organic Compounds Emitted by Fragrant Flowers of Three Tillandsia Species by HS-SPME/GC-MS Mame-Marietou Lo,Zohra Benfodda,David Bénimélis,Jean-Xavier Fontaine,Roland Moliniéet al. Metabolites, 2021, 11 (9), pp.594. ⟨10.3390/metabo11090594⟩ Article dans une revue hal-03334373v1
Development of a HS-SPME/GC-MS Method for the Extraction and Identification of the Volatile Compounds Emitted by Flowers of Tillandsia xiphioides Mame-Marietou Lo,Zohra Benfodda,David Bénimélis,Jean-Xavier J.-X. Fontaine,Roland Moliniéet al. ACS Omega, 2021, 6 (19), pp.12691-12698. ⟨10.1021/acsomega.1c00917⟩ Article dans une revue hal-03243914v1
Synthesis, Structure Elucidation, Antibacterial Activities, and Synergistic Effects of Novel Juglone and Naphthazarin Derivatives Against Clinical Methicillin-Resistant Staphylococcus aureus Strains Valentin Duvauchelle,Chaimae Majdi,David Bénimélis,Catherine Dunyach-Remy,Patrick Meffreet al. Frontiers in Chemistry, 2021, 9, ⟨10.3389/fchem.2021.773981⟩ Article dans une revue hal-03446358v1
Evaluation of Knowledge and Risk Perception about Antibiotic Resistance in Biology and Mathematics Young Students in Nîmes University in France Valentin Duvauchelle,Elsa Causse,Julien Michon,Patrick Rateau,Karine Weisset al. International Journal of Environmental Research and Public Health, 2021, 18 (18), pp.9692. ⟨10.3390/ijerph18189692⟩ Article dans une revue hal-03344418v1
Improved synthesis, resolution, absolute configuration determination and biological evaluation of HLM006474 enantiomers Miyanou Rosales-Hurtado,Alexandre Lebeau,Cyril Bourouh,Gerardo Cebrian Cebrian-Torrejon,Muriel Albalatet al. Bioorganic and Medicinal Chemistry Letters, 2019, 29, pp.380-382. ⟨10.1016/j.bmcl.2018.12.037⟩ Article dans une revue hal-01968387v1
Synthesis of histidine kinase inhibitors and their biological properties Miyanou Rosales-Hurtado,Patrick Meffre,Hendrik Szurmant,Zohra Benfodda Medicinal Research Reviews, 2019, ⟨10.1002/med.21651⟩ Article dans une revue hal-02400521v1
Ethynylglycine synthon, a useful precursor for the synthesis of biologically active compounds: an update. Part II: synthetic uses of ethynylglycine synthon Zohra Benfodda,David Bénimélis,Gianna Reginato,Patrick Meffre Amino Acids, 2018, 50 (10), pp.1307-1328. ⟨10.1007/s00726-018-2628-1⟩ Article dans une revue hal-01859944v1
Synthesis of 1,4-disubstituted 1,2,3-triazole Derivatives Using Click Chemistry and their Src Kinase Activities Alexandre Lebeau,Cyril Abrioux,David Bénimèlis,Zohra Benfodda,Patrick Meffre Medicinal Chemistry, 2017, Medicinal Chemistry, 13, pp.40-48. ⟨10.2174/1573406412666160404125718⟩ Article dans une revue hal-01495029v1
Spatial distribution of triazine residues in a shallow alluvial aquifer linked to groundwater residence time Lara Sassine,Corinne Le Gal La Salle,Mahmoud Khaska,Patrick Verdoux,Patrick Meffreet al. Environmental Science and Pollution Research, 2017, 24 (8), pp.6878-6888. ⟨10.1007/s11356-016-7224-x⟩ Article dans une revue hal-01544262v1
Synthesis of a Novel Rhizobitoxine-Like Triazole-Containing Amino Acid Thibaut Boibessot,David Bénimélis,Marion Jean,Zohra Benfodda,Patrick Meffre SYNLETT, 2016, 27 (19), pp.2685-2688. ⟨10.1055/s-0036-1588300⟩ Article dans une revue hal-01404310v1
Advances in the synthesis of α‑quaternary α‑ethynyl α‑amino acids Thibaut Boibessot,David Bénimélis,Patrick Meffre,Zohra Benfodda Amino Acids, 2016, 48 (9), pp.2081-2101. ⟨10.1007/s00726-016-2276-2⟩ Article dans une revue hal-01540958v1
The Rational Design, Synthesis, and Antimicrobial Properties of Thiophene Derivatives That Inhibit Bacterial Histidine Kinases Thibaut Boibessot,Christopher Zschiedrich,Alexandre Lebeau,David Bénimélis,Catherine Dunyach-Remyet al. Journal of Medicinal Chemistry, 2016, 59, pp.8830-8847. ⟨10.1021/acs.jmedchem.6b00580⟩ Article dans une revue hal-01543599v1
Synthesis, resolution, and determination of absolute configuration of protected α-ethynylphenylalanine enantiomers Z Benfodda,David Bénimèlis,Marion Jean,Jean-Valère Naubron,Valerie Rollandet al. Amino Acids, 2015, 47 (5), pp.899-907. ⟨10.1007/s00726-015-1917-1⟩ Article dans une revue hal-02002634v1
Ethynylglycine synthon, a useful precursor for the synthesis of biologically active compounds: an update Zohra Benfodda,David Bénimélis,Gianna Reginato,Patrick Meffre Amino Acids, 2015, 47 (2), pp.271-279. ⟨10.1007/s00726-014-1902-0⟩ Article dans une revue hal-01676812v1
Synthesis of cis-5-Trifluoromethylproline from L-Glutamic Acid Stéphanie Ortial,Rajesh Dave,Zohra Benfodda,David Bénimélis,Patrick Meffre SYNLETT, 2013, 2014 (25), pp.0569-0573. ⟨10.1055/s-0033-1340553⟩ Article dans une revue hal-00969187v1
Chemoenzymatic routes to enantiomerically pure 2-azatyrosine and 2-, 3- and 4-pyridylalanine derivatives Amer Moussa,Patrick Meffre,Jean Martinez,Valérie Rolland Amino Acids, 2012, 42, pp.1339-1348. ⟨10.1007/s00726-010-0829-3⟩ Article dans une revue istex hal-00616942v1
New unsaturated amino acids containing an allylsilane moiety on the lateral chain Gianna Reginato,Alessandro Mordini,Patrick Meffre,Alice Tenti,Michela Valacchiet al. Tetrahedron: Asymmetry, 2006, 17 (6), pp.922-926. ⟨10.1016/j.tetasy.2006.02.017⟩ Article dans une revue hal-02002619v1
NEW ROUTES TO a-AMINO ACID b,g-THIOENOL ETHER DERIVATIVES Patrick Meffre,Patrick Mcffrc,Philippe Durand Synthetic Communications, 2006, 32 (2), pp.287-296 Article dans une revue hal-02002695v1
Ethynylglycine synthon from Garner's aldehyde: a useful precursor for the synthesis of non-natural amino acids G. Reginato,Patrick Meffre,F. Gaggini Amino Acids, 2005, 29 (2), pp.81-87. ⟨10.1007/s00726-005-0184-y⟩ Article dans une revue hal-02002665v1
γ-Fluorinated analogues of glutamic acid and glutamine R. Dave,B. Badet,Patrick Meffre Amino Acids, 2003, 24 (3), pp.245-261. ⟨10.1007/s00726-002-0410-9⟩ Article dans une revue hal-02002676v1
Practical one-step synthesis of ethynylglycine synthon from Garner's aldehyde Patrick Meffre,Sébastien Hermann,Philippe Durand,Gianna Reginato,Antonella Riu Tetrahedron, 2002, 58 (25), pp.5159-5162. ⟨10.1016/S0040-4020(02)00438-6⟩ Article dans une revue istex hal-02002686v1
A concise synthesis of l-4,4-difluoroglutamine Patrick Meffre,Rajesh Dave,Jacques Leroy,Bernard Badet Tetrahedron Letters, 2001, 42 (49), pp.8625-8627. ⟨10.1016/S0040-4039(01)01866-4⟩ Article dans une revue istex hal-02002782v1
Chemoenzymatic synthesis of enantiopure 1,1′-disubstituted ferrocenyl aminoalcohols Lars Veum,Hélène Brouard,Patrick Meffre,Marc Larchevêque,Didier Buisson*et al. Tetrahedron: Asymmetry, 2000, 11 (20), pp.4055-4059 Article dans une revue hal-02002779v1
Syntheses of optically active 2-amino-4-oxobutyric acid and N,O-protected derivatives Patrick Meffre Amino Acids, 1999, 16 (3-4), pp.251-272 Article dans une revue hal-02002777v1
METHYL (S)-2-PHTHALIMIDO-4-OXOBUTANOATE Patrick Meffre,Philippe Durand,François Le Goffic Organic Syntheses : An annual publication of satisfactory methods for the preparation of organic chemicals, 1999, 76, pp.123 Article dans une revue hal-02002772v1
Synthesis of New Chiral Vinyl Halides from L-Serinal Eric Branquet,Patrick Meffre,Philippe Durand,François Le Goffic Synthetic Communications, 1998, 28 (4), pp.613-622 Article dans une revue hal-02002767v1
β,γ-Alkynylα-amino acids: a synthetic challenge Patrick Meffre,F. Le Goffic Amino Acids, 1996, 11 (3-4), pp.313-328 Article dans une revue hal-02002756v1
Synthesis of optically active β,γ-alkynylglycine derivatives Patrick Meffre,Laurence Gauzy,Eric Branquet,Philippe Durand,François Le Goffic Tetrahedron, 1996, 52 (34), pp.11215-11238 Article dans une revue hal-02002738v1
Straightforward Synthesis of Optically Pure Methyl (S)-2-Phthalimido-4-oxobutanoate and Some of Its Acetal and Thioacetal Derivatives Patrick Meffre,Philippe Durand,François Le Goffic Synthesis: Journal of Synthetic Organic Chemistry, 1995, 1995 (09), pp.1111-1114 Article dans une revue hal-02002741v1
En route to optically active ethynylglycine derivatives Patrick Meffre,Laurence Gauzy,Chantal Perdigues,Florence Desanges-Levecque,Eric Branquetet al. Tetrahedron Letters, 1995, 36 (6), pp.877-880 Article dans une revue hal-02010594v1
A Straightforward Synthesis of N-Boc-L-serinal and N-Boc-L-threoninal Acetonides Patrick Meffre,Philippe Durand,Eric Branquet,Fran°cois Le Goffic Synthetic Communications, 1994, 24 (15), pp.2147-2152 Article dans une revue hal-02002737v1
Asymmetric dihydroxylation of olefins with a simple chiral ligand Stephen Hanessian,Patrick Meffre,Mario Girard,Serge Beaudoin,Jean Yves Sanceauet al. Journal of Organic Chemistry, 1993, 58 (8), pp.1991-1993 Article dans une revue hal-02002729v1
A new class of unusual α-aminoacids : α-aminoacid β,γ-enol thioethers Patrick Meffre,L. Vo-Quang,Y. Vo-Quang,F. Le Goffic Tetrahedron Letters, 1991, 32 (36), pp.4717-4720. ⟨10.1016/S0040-4039(00)92290-1⟩ Article dans une revue istex hal-02010629v1
A new class of unusual α-aminoacids : α-aminoacid β,γ-enol thioethers Patrick Meffre,H. Lhermitte,L. Vo-Quang,Y. Vo-Quang,F. Le Goffic Tetrahedron Letters, 1991, 32 (36), pp.4717-4720. ⟨10.1016/S0040-4039(00)92290-1⟩ Article dans une revue istex hal-02002724v1
Unusual α-aminoacids from vinylglycine Patrick Meffre,L. Vo-Quang,Y. Vo-Quang,F. Le Goffic Tetrahedron Letters, 1990, 31 (16), pp.2291-2294. ⟨10.1016/0040-4039(90)80209-5⟩ Article dans une revue istex hal-02002721v1
Unusual α-aminoacids from vinylglycine Patrick Meffre,L. Vo-Quang,Y. Vo-Quang,F. Le Goffic Tetrahedron Letters, 1990, 31 (16), pp.2291-2294. ⟨10.1016/0040-4039(90)80209-5⟩ Article dans une revue istex hal-02010624v1
N-(Benzyloxycarbonyl)-L-vinylglycike Methyl Ester from L-Methionine Methyl Ester Hydrochloride Patrick Meffre,Liliane Vo-Quang,Yen Vo-Quang,François Le Goffic Synthetic Communications, 1989, 19 (20), pp.3457-3468 Article dans une revue hal-02002719v1

Communication dans un congrès (16)

Analysis of the Volatile Organic Compounds of Tillandsia flowers by HS-SPME/GC-MS Alexandre Gonzalez,Zohra Benfodda,David Bénimélis,Jean-Xavier J.-X. Fontaine,Roland Moliniéet al. Analytics 2022, Sep 2022, Nantes, France Communication dans un congrès hal-03806502v1
E2f1 contrôle la fonction et l’identité de la cellule beta pancréatique par un mécanisme dépendant des enzymes HDAC Cyril Bourouh,Frédérik Oger,Xavier Gromada,Maeva Moreno,Charlène Carneyet al. Congrès de la Société Francophone du Diabète 2021, SFD, Mar 2021, Strasbourg (100% virtuel), France Communication dans un congrès hal-04461303v1
Rational design, synthesis and antimicrobial properties of thiophene derivatives that inhibit bacterial histidine kinases Zohra Benfodda,Miyanou Rosales-Hurtado,Thibaut Boibessot,Christopher Zschiedrich,Alexandre Lebeauet al. 2nd international conference Antimicrobial and antibacterial Istanbul Turkey, Nov 2019, Istanbul, Turkey Communication dans un congrès hal-02400581v1
Rational design, synthesis and antimicrobial properties of thiophene derivatives that inhibit bacterial histidine kinases Zohra Benfodda,Thibaut Boibessot,Christopher Zschiedrich,Alexandre Lebeau,David Bénimèliset al. 24th ISCB international conference-Frontier research in chemistry&biology interface, Jan 2018, JAIPUR, India Communication dans un congrès hal-01998540v1
Synthesis of 5-trifluoromethylproline from L-glutamic acid Stéphanie Ortial,Rajesh Dave,Zohra Benfodda,David Bénimèlis,Patrick Meffre 14th International Congress on Amino Acids, Peptides and Proteins, Aug 2015, Wien, Austria. pp.615-636, ⟨10.1007/s00726-015-2160-5⟩ Communication dans un congrès hal-02010135v1
Addendum to Abstracts presented at the 14th International Congress on Amino Acids, Peptides and Proteins Patrick Meffre,Zohra Benfodda,David Bénimèlis,Stéphanie Ortial,Valerie Rollandet al. 14th International Congress on Amino Acids, Peptides and Proteins, Aug 2015, Vienna, Austria. pp.615-636 Communication dans un congrès hal-02002708v1
Synthesis of acetylenic analogue of phenylalanine. Zohra Benfodda,Stéphanie Ortial,David Bénimélis,Valerie Rolland,Patrick Meffre 13th International Congress on Amino acids, peptides and proteins, Oct 2013, Galvestion (Texas), United States. pp.611, ⟨10.1007/s00726-013-1540-y⟩ Communication dans un congrès hal-00993416v1
New developments in the synthesis of acetylenic analogues of glutamate Patrick Meffre,Zohra Benfodda,David Bénimélis,Valérie Rolland,Francine C. Acher 12 th International Congress on Amino Acids, Peptides and Proteins, Aug 2011, Beijing, China. pp.S79, ⟨10.1007/s00726-011-0955-6⟩ Communication dans un congrès istex hal-00621161v1
Synthesis of acetylenic analogues of glutamate Patrick Meffre,Zohra Benfodda,David Bénimèlis,Guillaume Vierling,Francine C. Acher 10th International Congress on Amino Acids and Proteins (ICAAP), Aug 2007, Kalithea, Chalkidiki, Greece. pp.I-LXX, ⟨10.1007/s00726-007-0578-0⟩ Communication dans un congrès hal-02010124v1
Synthesis of acetylenic analogues of glutamate Zohra Benfodda,David Bénimèlis,Patrick Meffre,Francine C. Acher 10th International Congress on amino acids and proteins, Aug 2007, Kallithea, Greece Communication dans un congrès hal-01998510v1
New developments in the synthesis of fluorinated analogues of glutamic acid and glutamine Patrick Meffre,Rajesh Dave,Bernard Badet 8th International Congress on Aminoacids, Sep 2003, Roma, Italy. pp.111-204, ⟨10.1007/s00726-003-0037-5⟩ Communication dans un congrès istex hal-02010117v1
Synthesis and biological evaluation of optically active fluorinated analogues of glutamine Patrick Meffre,Rajesh Dave,Bernard Badet 7th International Congress on Amino Acids and Proteins, Aug 2001, Wien, Austria. pp.1-90, ⟨10.1007/s007260170030⟩ Communication dans un congrès hal-02010112v1
Synthesis of optically active fluorinated analogues of glutamic acid and glutamine with potential biological activity Patrick Meffre,Jacques Leroy,Bernard Badet 6th International Congress on Amino Acids, Aug 1999, Bonn, Germany. pp.1-129, ⟨10.1007/BF01362415⟩ Communication dans un congrès istex hal-02010105v1
Synthesis and uses of aspartaldehyde derivatives Patrick Meffre 5th International Congress on Aminoacids, Aug 1997, Kalithea, Chalkidiki, Greece. pp.25-89, ⟨10.1007/BF01373046⟩ Communication dans un congrès istex hal-02010098v1
New developments in the synthesis of optically active ethynylglycine derivatives Patrick Meffre 4th International Congress on Aminoacids, Aug 1995, Wien, Austria. ⟨10.1007/BF00811751⟩ Communication dans un congrès istex hal-02010089v1
Different aspects of synthetic approaches including enzymatic enantioselective synthesis of aminoacids Patrick Meffre,François Le Goffic 3rd International Congress on Aminoacids, Aug 1993, Wien, Austria. ⟨10.1007/BF00806197⟩ Communication dans un congrès istex hal-02010087v1

Poster de conférence (14)

Synergistic Effects of Novel Naphthoquinone Derivatives Against Clinical Methicilin-Resistant Staphylococcus aureus Strain Valentin Duvauchelle,Chaimae Majdi,David Bénimélis,Catherine Dunyach-Rémy,Patrick Meffreet al. REncontres en Chimie Organique Biologique 18 (RECOB18), Mar 2022, Aussois, France. Poster de conférence hal-03700525v1
Study of the bio monitoring potential of acclimated Tillandsia species in Occitanie for metal air pollution Alexandre Gonzalez,Patrick Meffre Natural Products and Biocontrol 2022, Sep 2022, Perpignan, France Poster de conférence hal-03806423v1
Synthesis and biological evaluations of new families of histidine kinases inhibitors Valentin Duvauchelle,Miyanou Rosales-Hurtado,Thibaut Boibessot,David Bénimèlis,Catherine Dunyach-Remyet al. GSO-JMJC-JED2019, Oct 2019, Montpellier, France. Poster de conférence hal-02333120v1
Trophic interactions between Pseudosphinx tetrio larvae and Allamanda cathartica Linda Matignon,Mame Marietou Lo,Antonio Doménech-Carbó,Muriel Sylvestre,Patrick Meffreet al. Caribbean Science and Innovation Meeting 2019, Oct 2019, Pointe-à-Pitre (Guadeloupe), France Poster de conférence hal-02893707v1
Synthesis of thiophene derivatives: Potential new inhibitors of histidine kinases Miyanou Rosales-Hurtado,Thibaut Boibessot,Christopher Zschiedrich,Alexandre Lebeau,David Béniméliset al. Rencontres en Chimie Organique Biologique (Recob 17), Mar 2018, Aussois, France. Poster de conférence hal-01997587v1
Improved synthesis, resolution, absolute configuration determination of HLM006474 enantiomer Patrick Meffre,Miyanou Rosales-Hurtado,Alexandre Lebeau,Gerardo Cebrian Cebrian-Torrejon,Muriel Albalatet al. XXII International conférence on Organic synthesis (22-ICOS), Sep 2018, Florence, Italy Poster de conférence hal-02011288v1
Design and synthesis of novel HLM 006474 derivatives. Zohra Benfodda,Gerardo Cebrian Cebrian-Torrejon,Bourguet Romane,Sciortino Giuseppe,Jean-Didier Maréchalet al. 24th ISCB international conference-Frontier research in chemistry&biology interface., Jan 2018, JAIPUR, India Poster de conférence hal-01998366v1
Synthesis of Novel Triazole Amino Acids Analogues of Natural Amino Acids Patrick Meffre,Thibaut Boibessot,David Bénimèlis,Zohra Benfodda 20th European symposium on Organic Chemistry (ESOC), Jul 2017, Cologne, Germany Poster de conférence hal-02011261v1
Rational design of potent histidine kinase inhibitors with antimicrobial activities. Zohra Benfodda,Christopher Zschiedrich,Alexandre Lebeau,Thibaut Boibessot,Marta Maria Peregoet al. Experimental Biology meeting in San Diego, Apr 2016, San Diego, United States. The FASEB Journal, 30 (S1), pp.lb146-lb146, ⟨10.1096/fasebj.30.1_supplement.lb146⟩ Poster de conférence hal-01998350v1
Design and synthesis of 1,4-disubstituted 1,2,3-triazole derivatives as Histidine Kinase inhibitor. Zohra Benfodda,Alexandre Lebeau,David Bénimèlis,Hendrik Szurmant,Patrick Meffre 77th Harden Conference: Two Component Signalling in Bacteria: Integrating Approaches and Science, Aug 2015, Warwickshire, United Kingdom Poster de conférence hal-01998338v1
Synthesis of triazole amino acids Zohra Benfodda,Thibaut Boibessot,Alexandre Lebeau,David Bénimèlis,Patrick Meffre 14th International Congress on Amino Acids, Peptides and Proteins, Aug 2015, Vienne, Austria Poster de conférence hal-01998273v1
Rational design of potent histidine kinase inhibitors with antimicrobial activities Zohra Benfodda,Christopher Zschiedrich,Alexandre Lebeau,Thibaut Boibessot,Patrick Meffreet al. 8ème congrès international sur les microorganismes gram-positive, Jun 2015, Montecatini, Italy Poster de conférence hal-01998292v1
Synthesis of ethynyl phenylalanine Zohra Benfodda,David Benimelis,Valerie Rolland,Thibaut Boibessot,Patrick Meffre 21ème journée de l’Institut de Recherche Pierre Fabre (IRPF) de chimie. Chambre de commerce et d’industrie de Castres, Sep 2014, Castres, France Poster de conférence hal-01998205v1
Synthesis of ethynyl phenylalanine Zohra Benfodda,David Bénimèlis,Valérie Rolland,Patrick Meffre The 5th European Chemistry Congress, Aug 2014, Istanbul, Turkey Poster de conférence hal-01998193v1

Chapitre d'ouvrage (2)

Synthetic uses of methionine Patrick Meffre,Liliane Vo-Quang,Yen Vo-Quang,François Le Goffic Amino Acid Derivatives : A Practical Approach, Ed. G. C. Barrett, The Practical Approach in Chemistry Series (Series Editors : L. M. Harwood, C. J. Moody), Oxford University Press, Dec. 1999, ISBN0198558538., 1999 Chapitre d'ouvrage hal-02010083v1
Synthetic uses of serine, threonine and cysteine Patrick Meffre,Liliane Vo-Quang,Yen Vo-Quang,François Le Goffic Amino Acid Derivatives : A Practical Approach, Ed. G. C. Barrett, The Practical Approach in Chemistry Series (Series Editors : L. M. Harwood, C. J. Moody), Oxford University Press, Dec. 1999, ISBN0198558538, 1999 Chapitre d'ouvrage hal-02010084v1

Pré-publication, Document de travail (2)

A crosstalk between E2F1 and GLP-1 signaling pathways modulates insulin secretion Cyril Bourouh,Emilie Courty,Gianni Pasquetti,Xavier Gromada,Nabil Rabhiet al. 2023 Pré-publication, Document de travail hal-04365604v1
Pancreatic β-cell specific loss of E2f1 impairs insulin secretion and β-cell identity through the epigenetic repression of non β-cell programs Frédérik Oger,Cyril Bourouh,Xavier Gromada,Maeva Moreno,Charlène Carneyet al. 2023 Pré-publication, Document de travail hal-04365611v1

N°spécial de revue/special issue (2)

Special issue: Synthesis and Medicinal Chemistry Patrick Meffre Amino Acids, 29 (2), pp.79-79, 2005, ⟨10.1007/s00726-005-0236-3⟩ N°spécial de revue/special issue istex hal-02010122v1
Special Issue: Synthesis Patrick Meffre,S. Bittner Amino Acids, 24, pp.229-229, 2003, ⟨10.1007/s007260300001⟩ N°spécial de revue/special issue istex hal-02010114v1