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Perrine Paul-Gilloteaux

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Présentation

I'm a CNRS Research Engineer, specialized in computer vision and bio image analysis. After my electrical engineering studies, with a computer vision option, I did my PhD with a company (Medtronic Surgical Navigation, Boulder USA) and the ViSages team (INRIA, INSERM, CNRS) under the supervision of Dr. Pierre Jannin. I was working on the tracking of deformations of the brain during craniotomy in brain surgery, in order to relocate information from different exams of the patient , in particular indicated functional areas, such as language or motor area of the brain and to display them in the surgical microscope. For this, I was creating stereoscopic reconstruction from the surgical microscope binocular, and I developed a new method for the tracking of surface deformation, based on an hybrid approach of point cloud registration and of video tracking. I did a first postdoc as experienced Researcher in a Marie-Curie network, ARIS\*ER to work on augmented reality in surgery, and in particular the segmentation of tumors in ultrasound based on wavelet analysis of the ultrasound raw signal. I then got a post-doc position in Maynooth, Ireland (close to Dublin), in the Hamilton Institute which is an applied mathematics institute. I was in the Systems Biology group, where I've developed with my colleagues an intelligent fluorescent microscope, taking the decision of the area to image and of the frequency of acquisition, based on real time analysis of the image content (cell segmentation and cell tracking). In 2010, I joined the CNRS as research Engineer in the PICT IBISA cell and tissue microscopy facility in Institut Curie, Paris, France. My job was to support the biologists in image analysis, by adapting existing sofwtare or developping new methods. In June 2015, I've joined the [Structure Federative de Recherche in Health](https://sfrsante.univ-nantes.fr/) of Nantes (France), where I work for the facility, and on my own research activities I am now leading R&D activities in multimodal image analysis, through the [ANR CROCOVAL](https://anrcrocoval.github.io/) , and heading [MicroPICell](https://micropicell.univ-nantes.fr/), a microscopy facility performing services and R& D in histology, photonic microscopy and image analysis and management. I am one of the co-funder of COST action [NEUBIAS](http://www.neubias.org), for which I lead the group creating [biii.eu](http://www.biii.eu) and [edam bio imaging](https://bioportal.bioontology.org/ontologies/EDAM-BIOIMAGING?p=classes) and is part of the core group managing the full network, and vice chair and the [COMULIS](https://www.comulis.eu/) COST action.

Domaines de recherche


Publications

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Image document

Bioimage informatics: Investing in software usability is essential

Perrine Paul-Gilloteaux
PLoS Biology, 2023, 21 (7), pp.e3002213. ⟨10.1371/journal.pbio.3002213⟩
Article dans une revue hal-04175990v1
Image document

Visualizing enteric nervous system activity through dye-free dynamic full-field optical coherence tomography

Tony Durand , Perrine Paul-Gilloteaux , Michalina Gora , Lara Laboudie , Emmanuel Coron
Communications Biology, 2023, 6 (1), pp.236. ⟨10.1038/s42003-023-04593-9⟩
Article dans une revue hal-04013867v1

Sample preparation and image registration for correlative cryo-FM and cryo-FIB-SEM of plunge-frozen mammalian cells

Nadav Scher , Katya Rechav , Perrine Paul-Gilloteaux , Ori Avinoam
STAR Protocols, 2022, 3 (1), pp.101142. ⟨10.1016/j.xpro.2022.101142⟩
Article dans une revue hal-03745072v1
Image document

Multimodality imaging and transcriptomics to phenotype mitral valve dystrophy in a unique knock-in Filamin-A rat model

Constance Delwarde , Claire Toquet , Pascal Aumond , Amir Hossein Kayvanjoo , Adrien Foucal
Cardiovascular Research, 2022, 119 (3), pp.759-771. ⟨10.1093/cvr/cvac136⟩
Article dans une revue hal-03765601v1
Image document

REMBI: Recommended Metadata for Biological Images—enabling reuse of microscopy data in biology

Ugis Sarkans , Wah Chiu , Lucy Collinson , Michele Darrow , Jan Ellenberg
Nature Methods, 2021, ⟨10.1038/s41592-021-01166-8⟩
Article dans une revue hal-03232628v1

Protocol for image registration of correlative soft X-ray tomography and super-resolution structured illumination microscopy images

Nina Vyas , Stephan Kunne , Thomas Fish , Ian Dobbie , Maria Harkiolaki
STAR Protocols, 2021, 2 (2), pp.100529. ⟨10.1016/j.xpro.2021.100529⟩
Article dans une revue hal-03223460v1
Image document

Correlated Multimodal Imaging in Life Sciences: Expanding the Biomedical Horizon

Andreas Walter , Perrine Paul-Gilloteaux , Birgit Plochberger , Ludek Sefc , Paul Verkade
Frontiers in Physics, 2020, 8, ⟨10.3389/fphy.2020.00047⟩
Article dans une revue hal-02539357v1
Image document

Automatic Registration of Correlative Microscopies with Error Assessment and Applications for the Optimization of Multimodal Acquisitions.

Guillaume Potier , Romain Capoulade , Jean Mérot , Frédéric Lavancier , Xavier Heiligenstein
Microscopy and Microanalysis, 2019, 25 (S2), pp.1020-1021. ⟨10.1017/S143192761900583X⟩
Article dans une revue hal-02267554v1

Linking and analyzing correlative datasets

Perrine Paul-Gilloteaux
ALL-HANDS NODES MEETINg&MORE, iNext DISCOVERY, Apr 2023, Heidelberg, Germany
Communication dans un congrès hal-04217201v1

Correlative microscopies : comulisglobe and news from ec-clem

Perrine Paul-Gilloteaux
France BioImaging CLEM day: What's new in multimodal imaging, Mar 2023, Paris, France
Communication dans un congrès hal-04217188v1

Image processing and analysis in clem : methods and pitfalls

Perrine Paul-Gilloteaux
Symposium on recent developments in cellular electron microscopy, AVIESAN ITMO MOLECULAR AND STRUCTURAL BASIS OF LIFE SCIENCES, Mar 2022, Paris, France
Communication dans un congrès hal-04217262v1
Image document

A Registration Error Estimation Framework for Correlative Imaging

Guillaume Potier , Frederic Lavancier , Stephan Kunne , Perrine Paul-Gilloteaux
2021 IEEE International Conference on Image Processing (ICIP), Sep 2021, Anchorage, United States. pp.131-135, ⟨10.1109/ICIP42928.2021.9506474⟩
Communication dans un congrès hal-03327500v1

Computer-assisted analysis of multimodal image data—perspectives and conclusion

Nataša Sladoje , Joakim Lindblad , Perrine Paul-Gilloteaux
Imaging Modalities for Biological and Preclinical Research: A Compendium, Volume 2, IOP Publishing, 2021, ⟨10.1088/978-0-7503-3747-2ch30⟩
Chapitre d'ouvrage hal-03232548v1