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Perrine Paul-Gilloteaux

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Présentation

I'm a CNRS Research Engineer, specialized in computer vision and bio image analysis. After my electrical engineering studies, with a computer vision option, I did my PhD with a company (Medtronic Surgical Navigation, Boulder USA) and the ViSages team (INRIA, INSERM, CNRS) under the supervision of Dr. Pierre Jannin. I was working on the tracking of deformations of the brain during craniotomy in brain surgery, in order to relocate information from different exams of the patient , in particular indicated functional areas, such as language or motor area of the brain and to display them in the surgical microscope. For this, I was creating stereoscopic reconstruction from the surgical microscope binocular, and I developed a new method for the tracking of surface deformation, based on an hybrid approach of point cloud registration and of video tracking. I did a first postdoc as experienced Researcher in a Marie-Curie network, ARIS\*ER to work on augmented reality in surgery, and in particular the segmentation of tumors in ultrasound based on wavelet analysis of the ultrasound raw signal. I then got a post-doc position in Maynooth, Ireland (close to Dublin), in the Hamilton Institute which is an applied mathematics institute. I was in the Systems Biology group, where I've developed with my colleagues an intelligent fluorescent microscope, taking the decision of the area to image and of the frequency of acquisition, based on real time analysis of the image content (cell segmentation and cell tracking). In 2010, I joined the CNRS as research Engineer in the PICT IBISA cell and tissue microscopy facility in Institut Curie, Paris, France. My job was to support the biologists in image analysis, by adapting existing sofwtare or developping new methods. In June 2015, I've joined the [Structure Federative de Recherche in Health](https://sfrsante.univ-nantes.fr/) of Nantes (France), where I work for the facility, and on my own research activities I am now leading R&D activities in multimodal image analysis, through the [ANR CROCOVAL](https://anrcrocoval.github.io/) , and heading [MicroPICell](https://micropicell.univ-nantes.fr/), a microscopy facility performing services and R& D in histology, photonic microscopy and image analysis and management. I am one of the co-funder of COST action [NEUBIAS](http://www.neubias.org), for which I lead the group creating [biii.eu](http://www.biii.eu) and [edam bio imaging](https://bioportal.bioontology.org/ontologies/EDAM-BIOIMAGING?p=classes) and is part of the core group managing the full network, and vice chair and the [COMULIS](https://www.comulis.eu/) COST action.

Domaines de recherche


Publications

xavier-heiligenstein
Image document

3D Correlative Cryo-Structured Illumination Fluorescence and Soft X-ray Microscopy Elucidates Reovirus Intracellular Release Pathway

Ilias Kounatidis , Megan Stanifer , Michael Phillips , Perrine Paul-Gilloteaux , Xavier Heiligenstein
Article dans une revue hal-02886173v1
Image document

Automatic Registration of Correlative Microscopies with Error Assessment and Applications for the Optimization of Multimodal Acquisitions.

Guillaume Potier , Romain Capoulade , Jean Mérot , Frédéric Lavancier , Xavier Heiligenstein
Microscopy and Microanalysis, 2019, 25 (S2), pp.1020-1021. ⟨10.1017/S143192761900583X⟩
Article dans une revue hal-02267554v1

eC-CLEM: A multidimension, multimodel software to correlate intermodal images with a focus on light and electron microscopy.

Xavier Heiligenstein , Perrine Paul-Gilloteaux , Graça Raposo , Jean Salamero
Methods in Cell Biology, 2018, pp.335-352. ⟨10.1016/bs.mcb.2017.03.014⟩
Article dans une revue hal-01712180v1

eC-CLEM: flexible multidimensional registration software for correlative microscopies

Perrine Paul-Gilloteaux , Xavier Heiligenstein , Martin Belle , Marie-Charlotte Domart , Banafshe Larijani
Nature Methods, 2017, 14 (2), pp.102 - 103. ⟨10.1038/nmeth.4170⟩
Article dans une revue hal-01712184v1

eC-CLEM: Flexible Multidimensional Registration Software for Correlative Microscopies with Refined Accuracy Mapping

Xavier Heiligenstein , Perrine Paul-Gilloteaux , Martin Belle , Graca Raposo , Jean Salamero
Microscopy and Microanalysis, 2017, 23 (S1), pp.360-361. ⟨10.1017/S1431927617002483⟩
Article dans une revue hal-02735782v1
Image document

The CryoCapsule: Simplifying Correlative Light to Electron Microscopy

Xavier Heiligenstein , Jérôme Heiligenstein , Cédric Delevoye , Ilse Hurbain , Sabine Bardin
Traffic, 2014, 15 (6), pp.700 - 716. ⟨10.1111/tra.12164⟩
Article dans une revue hal-01712232v1

Le recalage d'image sous ICY

Perrine Paul-Gilloteaux , Xavier Heiligenstein
Journée Thématique conjointe sur le repositionnement et la relocalisation/recalage, Nov 2017, Orléans, France
Communication dans un congrès hal-02746899v1