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Philippe Bastin



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Redistribution of FLAgellar Member 8 during the trypanosome life cycle: Consequences for cell fate prediction

Estefanía Calvo-Álvarez , Serge Bonnefoy , Audrey Salles , Fiona Benson , Paul Mckean et al.
Cellular Microbiology, 2021, pp.e13347. ⟨10.1111/cmi.13347⟩
Journal articles pasteur-03230881v1
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The establishment of variant surface glycoprotein monoallelic expression revealed by single-cell RNA-seq of Trypanosoma brucei in the tsetse fly salivary glands

Sebastian Hutchinson , Sophie Foulon , Aline Crouzols , Roberta Menafra , Brice Rotureau et al.
PLoS Pathogens, 2021, 17 (9), pp.e1009904. ⟨10.1371/journal.ppat.1009904⟩
Journal articles pasteur-03661699v1
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Intraflagellar transport during assembly of flagella of different length in Trypanosoma brucei isolated from tsetse flies

Eloïse Bertiaux , Adeline Mallet , Brice Rotureau , Philippe Bastin
Journal of Cell Science, 2020, 133 (18), pp.jcs248989. ⟨10.1242/jcs.248989⟩
Journal articles pasteur-02970237v1
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Timing and original features of flagellum assembly in trypanosomes during development in the tsetse fly

Moara Lemos , Adeline Mallet , Eloise Bertiaux , Albane Imbert , Brice Rotureau et al.
Parasites & Vectors, 2020, 13, pp.169. ⟨10.1186/s13071-020-04026-0⟩
Journal articles hal-02553740v1

IFT25 is required for the construction of the trypanosome flagellum

Diego Huet , Thierry Blisnick , Sylvie Perrot , Philippe Bastin
Journal of Cell Science, 2019, ⟨10.1242/jcs.228296⟩
Journal articles hal-03246254v1
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Moteurs moléculaires et microtubules : relation libre, imposée ou sélective ?

Adeline Mallet , Philippe Bastin
médecine/sciences, 2019, 35 (4), pp.302-304. ⟨10.1051/medsci/2019062⟩
Journal articles hal-02984723v1
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Bidirectional intraflagellar transport is restricted to two sets of microtubule doublets in the trypanosome flagellum

Eloise Bertiaux , Adeline Mallet , Cécile Fort , Thierry Blisnick , Serge Bonnefoy et al.
Journal of Cell Biology, 2018, ⟨10.1083/jcb.201805030⟩
Journal articles pasteur-01931458v1

Biallelic Mutations in LRRC56, Encoding a Protein Associated with Intraflagellar Transport, Cause Mucociliary Clearance and Laterality Defects

Serge Bonnefoy , Christopher M.Watson , Kristin Kernohan , Moara Lemos , Sebastian Hutchinson et al.
American Journal of Human Genetics, 2018, 103 (5), pp.727 - 739. ⟨10.1016/j.ajhg.2018.10.003⟩
Journal articles pasteur-01931456v1

Flagellar incorporation of proteins follows at least two different routes in trypanosomes

Laetitia Vincensini , Thierry Blisnick , Eloise Bertiaux , Sebastian Hutchinson , Christina Georgikou et al.
Biology of the Cell, 2018, 110 (2), pp.33-47. ⟨10.1111/boc.201700052⟩
Journal articles pasteur-03112358v1
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A Grow-and-Lock Model for the Control of Flagellum Length in Trypanosomes

Eloise Bertiaux , Benjamin Morga , Thierry Blisnick , Brice Rotureau , Philippe Bastin et al.
Current Biology - CB, 2018, 28 (23), pp.3802-3814.e3. ⟨10.1016/j.cub.2018.10.031⟩
Journal articles pasteur-01928242v1

STEM tomography analysis of the trypanosome transition zone

Sylvain Trépout , Anne-Marie Tassin , Sergio Marco , Philippe Bastin
Journal of Structural Biology, 2017, ⟨10.1016/j.jsb.2017.12.005⟩
Journal articles hal-02323498v1
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Intraflagellar transport is required for the maintenance of the trypanosome flagellum composition but not its length.

Cécile Fort , Serge Bonnefoy , Linda Kohl , Philippe Bastin
Journal of Cell Science, 2016, 129 (15), pp.3026-41. ⟨10.1242/jcs.188227⟩
Journal articles pasteur-01351023v1
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IFT81, encoding an IFT-B core protein, as a very rare cause of a ciliopathy phenotype

Isabelle Perrault , Jan Halbritter , Jonathan D. Porath , Xavier Gerard , Daniela A. Braun et al.
Journal of Medical Genetics, 2015, 52 (10), pp.657-665. ⟨10.1136/jmedgenet-2014-102838⟩
Journal articles pasteur-01301204v1
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The Flagellar Arginine Kinase in Trypanosoma brucei Is Important for Infection in Tsetse Flies

Cher-Pheng Ooi , Brice Rotureau , Simonetta Gribaldo , Christina Georgikou , Daria Julkowska et al.
PLoS ONE, 2015, 10 (7), pp. e0133676. ⟨10.1371/journal.pone.0133676⟩
Journal articles pasteur-01301205v1
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The more we know, the more we have to discover: an exciting future for understanding cilia and ciliopathies.

Alexandre Benmerah , Bénédicte Durand , Rachel H Giles , Tess Harris , Linda Kohl et al.
Cilia, 2015, 4 (1), pp.5. ⟨10.1186/s13630-015-0014-0⟩
Journal articles pasteur-01514418v1

Imaging intraflagellar transport in trypanosomes

Julien Santi-Rocca , Nicolas Chenouard , Cécile Fort , Thibault Lagache , Jean-Christophe Olivo-Marin et al.
Methods in Cell Biology, 2015, Methods in Cilia & Flagella, 127, pp.487-508. ⟨10.1016/bs.mcb.2015.01.005⟩
Journal articles pasteur-01301203v1
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Social motility in African trypanosomes: fact or model?

Philippe Bastin , Brice Rotureau
Trends in Parasitology, 2015, 31 (2), pp.37-8. ⟨10.1016/⟩
Journal articles pasteur-01301206v1

Scanning transmission electron microscopy through-focal tilt-series on biological specimens

Sylvain Trépout , Cédric Messaoudi , Sylvie Perrot , Philippe Bastin , Sergio Marco et al.
Micron, 2015, 77, pp.9-15. ⟨10.1016/j.micron.2015.05.015⟩
Journal articles pasteur-01301207v1
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Flagellar membranes are rich in raft-forming phospholipids

Mauro Serricchio , Adrien W. Schmid , Michael E. Steinmann , Erwin Sigel , Monika Rauch et al.
Biology Open, 2015, 4 (9), pp.1143-1153. ⟨10.1242/bio.011957⟩
Journal articles pasteur-01301208v1
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Boarder control on the IFT train.

Cécile Fort , Philippe Bastin
eLife, 2014, 3, pp.e02531. ⟨10.7554/eLife.02531⟩
Journal articles pasteur-01301210v1
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The Leishmania donovani chaperone cyclophilin 40 is essential for intracellular infection independent of its stage-specific phosphorylation status.

Wai-Lok Yau , Pascale Pescher , Andrea Macdonald , Sonia Hem , Dorothea Zander et al.
Molecular Microbiology, 2014, 93 (1), pp.80-97. ⟨10.1111/mmi.12639⟩
Journal articles hal-01054664v1
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Forward motility is essential for trypanosome infection in the tsetse fly

Brice Rotureau , Cher-Pheng Ooi , Diego Huet , Sylvie Perrot , Philippe Bastin et al.
Cellular Microbiology, 2014, 16 (3), pp.425-433. ⟨10.1111/cmi.12230⟩
Journal articles pasteur-01301209v1
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Proteomic Analysis of Intact Flagella of Procyclic Trypanosoma brucei Cells Identifies Novel Flagellar Proteins with Unique Sub-localization and Dynamics

Ines Subota , Daria Julkowska , Laetitia Vincensini , Nele Reeg , Johanna Buisson et al.
Molecular and Cellular Proteomics, 2014, 13 (7), pp.1769-1786. ⟨10.1074/mcp.M113.033357⟩
Journal articles pasteur-01301216v1
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The GTPase IFT27 is involved in both anterograde and retrograde intraflagellar transport.

Diego Huet , Thierry Blisnick , Sylvie Perrot , Philippe Bastin
eLife, 2014, 3, pp.e02419. ⟨10.7554/eLife.02419⟩
Journal articles pasteur-01301212v1
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Elongation of the axoneme and dynamics of intraflagellar transport

Cécile Fort , Philippe Bastin
médecine/sciences, 2014, 30 (11), pp.955-961. ⟨10.1051/medsci/20143011008⟩
Journal articles pasteur-01301213v1
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The intraflagellar transport dynein complex of trypanosomes is made of a heterodimer of dynein heavy chains and of light and intermediate chains of distinct functions

Thierry Blisnick , Johanna Buisson , Sabrina Absalon , Alexandra Marie , Nadège Cayet et al.
Molecular Biology of the Cell, 2014, 25 (17), pp.2620-2633. ⟨10.1091/mbc.E14-05-0961⟩
Journal articles pasteur-01301215v1
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Generation of a Nanobody Targeting the Paraflagellar Rod Protein of Trypanosomes

Emmanuel Obishakin , Benoit Stijlemans , Julien Santi-Rocca , Isabel Vandenberghe , Bart Devreese et al.
PLoS ONE, 2014, 9 (12), pp.e115893. ⟨10.1371/journal.pone.0115893⟩
Journal articles pasteur-01301214v1
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Flagellar adhesion in Trypanosoma brucei relies on interactions between different skeletal structures in the flagellum and cell body

Brice Rotureau , Thierry Blisnick , Ines Subota , Daria Julkowska , Nadège Cayet et al.
Journal of Cell Science, 2014, 127 (1), pp.204-215. ⟨10.1242/jcs.136424⟩
Journal articles pasteur-01301211v1
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Trypanosoma brucei FKBP12 differentially controls motility and cytokinesis in procyclic and bloodstream forms.

Anaïs Brasseur , Brice Rotureau , Marjorie Vermeersch , Thierry Blisnick , Didier Salmon et al.
Eukaryotic Cell, 2013, 12 (2), pp.168-81. ⟨10.1128/EC.00077-12⟩
Journal articles pasteur-01371316v1

Molecular Basis of Tubulin Transport Within the Cilium by IFT74 and IFT81

Sagar Bhogaraju , Lukas Cajanek , Cécile Fort , Thierry Blisnick , Kristina Weber et al.
Science, 2013, 341 (6149), pp.1009-1012. ⟨10.1126/science.1240985⟩
Journal articles hal-03246299v1
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Getting to the heart of intraflagellar transport using Trypanosoma and Chlamydomonas models: the strength is in their differences.

Benjamin Morga , Philippe Bastin
Cilia, 2013, 2 (1), pp.16. ⟨10.1186/2046-2530-2-16⟩
Journal articles pasteur-00911797v1

Apoptotic marker expression in the absence of cell death in staurosporine-treated Leishmania donovani

Aude L. Foucher , Najma Rachidi , Sarah Gharbi , Thierry Blisnick , Philippe Bastin et al.
Antimicrobial Agents and Chemotherapy, 2013, 57 (3), pp.1252-1261. ⟨10.1128/AAC.01983-12⟩
Journal articles pasteur-01433417v1
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A new asymmetric division contributes to the continuous production of infective trypanosomes in the tsetse fly.

Brice Rotureau , Ines Subota , Johanna Buisson , Philippe Bastin
Development (Cambridge, England), 2012, 139 (10), pp.1842-50. ⟨10.1242/dev.072611⟩
Journal articles pasteur-01371317v1
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ALBA proteins are stage regulated during trypanosome development in the tsetse fly and participate in differentiation.

Ines Subota , Brice Rotureau , Thierry Blisnick , Sandra Ngwabyt , Mickaël Durand-Dubief et al.
Molecular Biology of the Cell, 2011, 22 (22), pp.4205-19. ⟨10.1091/mbc.E11-06-0511)⟩
Journal articles pasteur-01371322v1
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The importance of model organisms to study cilia and flagella biology

Laetitia Vincensini , Thierry Blisnick , Philippe Bastin
Biologie Aujourd'hui, 2011, 205 (1), pp.5-28. ⟨10.1051/jbio/2011005⟩
Journal articles hal-03246292v1
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Molecular bases of cytoskeleton plasticity during the Trypanosoma brucei parasite cycle.

Brice Rotureau , Ines Subota , Philippe Bastin
Cellular Microbiology, 2011, 13 (5), pp.705-16. ⟨10.1111/j.1462-5822.2010.01566.x⟩
Journal articles pasteur-01371324v1

1001 model organisms to study cilia and flagella

Laetitia Vincensini , Thierry Blisnick , Philippe Bastin
Biology of the Cell, 2011, 103 (3), pp.109-130. ⟨10.1042/BC20100104⟩
Journal articles hal-03246287v1
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The ciliary pocket: a once-forgotten membrane domain at the base of cilia

Rania Ghossoub , Anahi Mollà-Herman , Philippe Bastin , Alexandre Benmerah
Biology of the Cell, 2011, 103 (3), pp.131-144. ⟨10.1042/BC20100128⟩
Journal articles inserm-02263813v1

Quantitative proteome profiling informs on phenotypic traits that adapt Leishmania donovani for axenic and intracellular proliferation

Pascale Pescher , Thierry Blisnick , Philippe Bastin , Gerald F Späth
Cellular Microbiology, 2011, 13 (7), pp.978-991. ⟨10.1111/j.1462-5822.2011.01593.x⟩
Journal articles pasteur-01433560v1
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Cyclosporin A treatment of Leishmania donovani reveals stage-specific functions of cyclophilins in parasite proliferation and viability

Wai-Lok Yau , Thierry Blisnick , Jean-François Taly , Manuela Helmer-Citterich , Cordelia Schiene-Fischer et al.
PLoS Neglected Tropical Diseases, 2010, 4 (6), pp.e729. ⟨10.1371/journal.pntd.0000729⟩
Journal articles pasteur-01433566v1

The ciliary pocket: an endocytic membrane domain at the base of primary and motile cilia

Anahi Mollà-Herman , Rania Ghossoub , Thierry Blisnick , Alice Meunier , Catherine Serres et al.
Journal of Cell Science, 2010, 123 (10), pp.1785-1795. ⟨10.1242/jcs.059519⟩
Journal articles hal-02353018v1
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A novel function for the atypical small G protein Rab-like 5 in the assembly of the trypanosome flagellum

Christine Adhiambo , Thierry Blisnick , Géraldine Toutirais , Emmanuelle Delannoy , Philippe Bastin et al.
Journal of Cell Science, 2009, 122 (6), pp.834-841. ⟨10.1242/jcs.040444⟩
Journal articles hal-03246322v1
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The flagellum-mitogen-activated protein kinase connection in Trypanosomatids: a key sensory role in parasite signalling and development?

Brice Rotureau , Miguel Morales , Philippe Bastin , Gerald F Späth
Cellular Microbiology, 2009, 11 (5), pp.710 - 718. ⟨10.1111/j.1462-5822.2009.01295.x⟩
Journal articles pasteur-01849836v1
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Kinesin 9 family members perform separate functions in the trypanosome flagellum

Raphaël Demonchy , Thierry Blisnick , Caroline Deprez , Geraldine Toutirais , Celine Loussert et al.
Journal of Cell Biology, 2009, 187 (5), pp.615-622. ⟨10.1083/jcb.200903139⟩
Journal articles mnhn-02047425v1
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Intraflagellar Transport and Functional Analysis of Genes Required for Flagellum Formation in Trypanosomes.

Sabrina Absalon , Thierry Blisnick , Linda Kohl , Géraldine Toutirais , Gwénola Doré et al.
Molecular Biology of the Cell, 2008, 19 (3), pp.929-944. ⟨10.1091/mbc.E07-08-0749⟩
Journal articles pasteur-00217549v1

Flagellum elongation is required for correct structure, orientation and function of the flagellar pocket in Trypanosoma brucei.

Sabrina Absalon , Thierry Blisnick , Mélanie Bonhivers , Linda Kohl , Nadège Cayet et al.
Journal of Cell Science, 2008, 121 (Pt 22), pp.3704-16. ⟨10.1242/jcs.035626⟩
Journal articles hal-00426339v1
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Basal body positioning is controlled by flagellum formation in Trypanosoma brucei.

Sabrina Absalon , Linda Kohl , Carole Branche , Thierry Blisnick , Géraldine Toutirais et al.
PLoS ONE, 2007, 2, pp.e437. ⟨10.1371/journal.pone.0000437⟩
Journal articles pasteur-00169134v1
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Conserved and specific functions of axoneme components in trypanosome motility.

Carole Branche , Linda Kohl , Géraldine Toutirais , Johanna Buisson , Jacky Cosson et al.
Journal of Cell Science, 2006, 119 (Pt 16), pp.3443-55. ⟨10.1242/jcs.03078⟩
Journal articles hal-00108209v1
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Functional complementation of RNA interference mutants in trypanosomes.

Filippo Rusconi , Mickaël Durand-Dubief , Philippe Bastin
BMC Biotechnology, 2005, 5, pp.6. ⟨10.1186/1472-6750-5-6⟩
Journal articles inserm-00093264v1
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The flagellum of trypanosomes.

Linda Kohl , Philippe Bastin
Int Rev Cytol, 2005, 244, pp.227-85. ⟨10.1016/S0074-7696(05)44006-1⟩
Journal articles hal-00109408v1
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Novel roles for the flagellum in cell morphogenesis and cytokinesis of trypanosomes.

Linda Kohl , Derrick Robinson , Philippe Bastin
EMBO Journal, 2003, 22 (20), pp.5336-46. ⟨10.1093/emboj/cdg518⟩
Journal articles hal-00108210v1
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TbAGO1, an argonaute protein required for RNA interference, is involved in mitosis and chromosome segregation in Trypanosoma brucei.

Mickaël Durand-Dubief , Philippe Bastin
BMC Biology, 2003, 1, pp.2. ⟨10.1186/1741-7007-1-2⟩
Journal articles hal-00108479v1
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The role of G proteins in the control of intraflagellar transport

Diego Huet , Sylvie Perrot , Thierry Blisnick , Philippe Bastin
First International Cilia in Development and Disease Scientific Conference, May 2012, Londres, United Kingdom. , 1 (Suppl 1), pp.P24, 2012
Conference poster pasteur-00752960v1
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Sub-localisation of novel proteins with unique dynamics during assembly and maintenance of the eukaryotic flagellum

Philippe Bastin , D Julkowska , I Subota , L Vincensini , Thierry Blisnick et al.
First International Cilia in Development and Disease Scientific Conference, May 2012, London, United Kingdom. Cilia, 1 (Suppl 1), pp.P13, 2012, ⟨10.1186/2046-2530-1-S1-P13⟩
Conference poster pasteur-00752957v1

Progress in Research on African Trypanosomes: Highlights from an Exceptional Decade

Sebastian Hutchinson , Estefania Calvo-Alvarez , Jean Marc Tsagmo , Moara Lemos , Christelle Travaillé et al.
Lifecycles of Pathogenic Protists in Humans, 35, Springer International Publishing, pp.99-142, 2022, Microbiology Monographs, 978-3-030-80682-8. ⟨10.1007/978-3-030-80682-8_2⟩
Book sections pasteur-03695260v1