
Pierre-Herve Luppi
Présentation
Current position
Leader of the “SLEEP” Team (since 2011)
Education
1989 PhD, Neurosciences, University Lyon I
2009 Habilitation HDR, Neurosciences, University Lyon1
Research Career
1989-99 CNRS researcher (CR, 1st class), INSERM U52, University Lyon I
1999-2001 CNRS Research Director (DR2), INSERM U52, University Lyon I
2002-2010 Lab Director of the CNRS UMR5167, University Lyon I
Since 2010 CNRS Research Director (DR1), Lyon Neuroscience Research Center, University Lyon I
Publications and communications
Researcher unique identifier(s):
Researcher ID C-4333-2014
Orcid:/0000-0002-0503-423X
https://www.researchgate.net/profile/Pierre-Herve_Luppi
Web of Science, August 2021. Co-author of 142 articles in international peer-reviewed journals. H index = 51 ; Citations: 45.59times/article, 532 times/year (2020). Citations: >200 (8), 100-200 (14), 50-100 (29). Since 2011: 50 published abstracts, 1 book and 20 book chapters, 28 invited talks: 25 conferences/workshops (20 international; 5 national), 3 Summer schools
Academic Activities
- Lecturer for the Master programs in Neurosciences (Univ. Lyon 1), in Molecular and Cellular Biology (ENS Lyon, ENS Ulm) and in Medicine (DIU interuniversitaire Sommeil) and CMU, Univ. Genève (Switzerland).
- Since 1990, supervision of 13 doctoral students in Neurosciences, 6 obtained a permanent research position in French Research Institutes; 13 Master students; 7 post-doctoral fellows (Argentina, Japan, France, China, Brazil). Member of 17 PhD (10 as a reviewer) and 4 HDR panels.
Expertise, Committees, Editorial Board
- 2012-2020, President (actual position), Secretary (4 years), Vice President (4 years), European Sleep Research Society
- 2004-2017, 2020-, Member, scientific Committee, Société de Recherche et de Médecine du Sommeil (SFRMS)
- 2006-2010, Member, steering committee, Sleep plan, Ministry of Health
- 2007-2012, Member, steering Committee, “Neurological disabilities” Thematic Research and Health Network - RTRS, NeuroDis Foundation
- Co-Chair of International Conference: 50th anniversary of the discovery of paradoxical sleep, 2009, Lyon.
Editorial Board
- since 2009 Deputy Editor, Journal of Sleep research
Major funding since 2013
ANR-blanche: OPTOREM, 2013-2017, 382 720 €, Pierre-Hervé LUPPI Leader
Contrat PEPS Exomod 2015-2017 : 35 000€, Pierre-Hervé LUPPI Leader
Grant Embassy France/Japon 2017/2018 : 20000€, Pierre-Hervé LUPPI Leader
Grant CAPES/COFECUB 2019-2021 : 80 000€, Pierre-Hervé LUPPI Leader
Grant Labex Cortex 2021-2023: 225000€, Pierre-Hervé Luppi coleader
ANR-blanche: HYPREM, 2022-2025, 250 000 €, Pierre-Hervé LUPPI Leader
Publications
Publications
Improving the spatial resolution and SNR of rat brain T2-weighted MR images: application of a super-resolution methodISMRM 23rd Annual Meeting & Exhibition, May 2015, Toronto, Canada
Communication dans un congrès
hal-01288505
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Multiple labels point-set registration2015 IEEE 12th International Symposium on Biomedical Imaging (ISBI), Apr 2015, New-York, United States. pp.609 - 612, ⟨10.1109/ISBI.2015.7163947⟩
Communication dans un congrès
hal-01272177
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Amélioration de résolution spatiale et SNR d’images cérébrales pondérées T2 de rat : application de la super-résolution2ème Congrès de la SFRMBM, Mar 2015, Grenoble, France
Communication dans un congrès
hal-01288527
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Hypothalamic regulation of REM sleep21st Congress of the European-Sleep-Research-Society, Sep 2012, Paris, France. pp.2-3
Communication dans un congrès
hal-02345917
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EMD-based analysis of rat EEG data for sleep state classificationBiosignals, Jan 2009, Porto, Portugal
Communication dans un congrès
inria-00570470
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REM sleep generating mechanisms19th Congress of the European-Sleep-Research-Society, Sep 2008, Glasgow, United Kingdom. pp.90
Communication dans un congrès
hal-02347342
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Potential role of A2A adenosine receptors in the activity of VLPO neurons during sleep19th Congress of the European-Sleep-Research-Society, Sep 2008, Glasgow, United Kingdom. pp.33
Communication dans un congrès
hal-02347264
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Neuromodulation of the sleep-promoting neurons2nd Interim Congress of the World Federation of Sleep Research and Sleep Medicine Societies, World Federation of Sleep Research and Sleep Medicine Societies, Sep 2005, New Delhi, India. pp.173-176
Communication dans un congrès
hal-02351251
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Serotonin modulation reveals two types of GABAergic sleep promoting neurons in the ventrolateral preoptic nucleus (VLPO)17th Annual Meeting of the Associated-Professional-Sleep-Societies, Associated-Professional-Sleep-Societies (APSS), Jun 2003, Chicago, United States. pp.A33
Communication dans un congrès
hal-02351453
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Effect of the wake-promoting agent modafinil on sleep-promoting neurons from the ventrolateral preoptic nucleus: An in vitro pharmacological study17th Annual Meeting of the Associated-Professional-Sleep-Societies, Associated-Professional-Sleep-Societies (APSS), Jun 2003, Chicago, United States. pp.A7
Communication dans un congrès
hal-02351465
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Sleep-waking cycle and EEG rhythmic activities in mice lacking M2, M3, M4 or M2/M4 muscarinic receptors17th Annual Meeting of the Associated-Professional-Sleep-Societies, Associated-Professional-Sleep-Societies (APSS), Jun 2003, Chicago, United States. pp.A67
Communication dans un congrès
hal-02351491
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Localization of the gabaergic and non-gabaergic neurons projecting to the sublaterodorsal nucleus and potentially gating paradoxical sleep onset17th Annual Meeting of the Associated-Professional-Sleep-Societies, Jun 2003, Chicago, United States. pp.A36
Communication dans un congrès
hal-02351443
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The neurophysiology and neurobiology of wakefulness and non-rapid eye movement (NREM) sleepEuropean Sleep Medicine Textbook (Second Edition), European Sleep Research Society (ESRS), 2021
Chapitre d'ouvrage
hal-03748168
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The neurobiology and neurophysiology of paradoxical (REM) sleepClaudio Bassetti, Walter McNicholas, Tiina Paunio and Phillip Peigneux. European Sleep Medicine Textbook "(Second Edition), section Physiological basis of sleep., European Sleep Research Society (ESRS, 2021, 9781119789017
Chapitre d'ouvrage
hal-03748181
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Neuroanatomical and neurochemical systems involved in paradoxical sleep (PS) generationHandbook of Behavioral Neuroscience,, 30, Hans C Dringenberg. Academic Press, Elsevier, pp.239-248, 2019, Handbook of Sleep Research
Chapitre d'ouvrage
hal-02339591
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Sleep-wake physiology (chapter 23)Handbook of Clinical Neurology 3rd Series, vol 160. Clinical Neurophysiology: basis and technical aspects., 2019
Chapitre d'ouvrage
hal-02339580
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Neuroanatomical and Neurochemical Bases of Vigilance StatesSpringer Eds (Berlin). Handbook of experimental pharmacology, pp.35-58, 2018, ⟨10.1007/164_2017_84⟩
Chapitre d'ouvrage
hal-02329205
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Neurobiology of REM sleepChokroverty and Ferini-Strambi. Oxford Textbook of Sleep Disorders, Oxford University Press, pp.15-22, 2017, 9780199682003. ⟨10.1093/med/9780199682003.003.0003⟩
Chapitre d'ouvrage
hal-02339681
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Impaired sleep and alertness in Parkinson’s Disease: What did we learn from animal models?Videnovic A., Högl B. Disorders of Sleep and Circadian Rhythms in Parkinson’s Disease, Springer-Verlag (Wien), pp.35-50, 2015
Chapitre d'ouvrage
hal-02372124
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Localization and Neurochemistry of Sleep-Wake Physiology and PathophysiologyMH. Kryger, AY. Avidan and RB. Berry. Atlas of Clinical Sleep Medicine (2nd edition), Elsevier Saunders, pp.28-34, 2014
Chapitre d'ouvrage
hal-02372139
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Networks of normal and disordered sleepFaingold C.L., Blumenfeld H. Neuronal Networks in Brain Function, CNS Disorders, and Therapeutics (First Edition), Elsevier Inc, Academic Press, pp.299-310, 2014
Chapitre d'ouvrage
hal-02372129
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Neuroanatomy and physiology of sleep and wakefulnessE. Nofzinger, P. Maquet and MJ. Thorpy. Neuroimaging of sleep and sleep disorders, Cambridge University Press (UK), pp.8-15, 2013
Chapitre d'ouvrage
hal-02372148
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Neurochemistry of sleep: an overview of animal experimental workAminoff MJ, Boller F and Swaab DF. Sleep Disorders Part 1, 98, Elsevier publisher, pp.173-190, 2011, Handbook of Clinical Neurology, ⟨10.1016/B978-0-444-52006-7.00011-3⟩
Chapitre d'ouvrage
hal-02372158
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Glutamatergic regulation of REM sleepBiranda N Mallick, SR Pandi-Perumal, Robert W. McCarley and Adrian R. Morrison. Rapid Eye Movement: Sleep Regulation and Function, Cambridge University Press, pp.214-222, 2011
Chapitre d'ouvrage
hal-02372173
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The Neurobiology of sleep-wake systems: an overviewChristian R. Baumann; Claudio L. Bassetti; Thomas E. Scammell. Narcolepsy: Pathophysiology, Diagnosis and Treatment, Springer Science, pp.107-120, 2011, 978-1-4419-8389-3. ⟨10.1007/978-1-4419-8390-9_10⟩
Chapitre d'ouvrage
hal-02372181
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Gamma-aminobutyric acid and the regulation of paradoxical, or rapid eye movement, sleepJaime Monti S. R. Pandi-Perumal and Christopher M. Sinton. Neurochemistry of Sleep and Wakefulness, Cambridge University Press, pp.85-108, 2009, 9780511541674. ⟨10.1017/CBO9780511541674.005⟩
Chapitre d'ouvrage
hal-02360504
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In Vitro Identification of the Presumed Sleep-promoting Neurons of the Ventrolateral Preoptic nucleus (VLPO)P-H. Luppi. Sleep: Circuits and Function 0-8493-1519-0, CRC Press, pp.272, 2004
Chapitre d'ouvrage
hal-00012375
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In vitro identification of the presumed sleep-promoting neurons of the ventrolateral preoptic nucleus (VLPO).P-H. LUPPI. Sleep, Circuits and Functions, CRC Press, pp.43-64, 2004, Frontiers in neuroscience
Chapitre d'ouvrage
hal-02372205
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The network responsible for paradoxical sleep onset and maintenance: a new theory based on the head-restrained rat modelP-H Luppi. Sleep, Circuits and Functions, CRC Press, pp.83-108, 2004, Frontiers in Neuroscience
Chapitre d'ouvrage
hal-02372219
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Norepinephrine and REM sleepMallick B.N. and Inoue S. Rapid eye movement sleep, Narosa Publishing House, pp.107-122, 1999
Chapitre d'ouvrage
hal-02372233
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Inhibitory mechanisms in the raphé dorsalis and locus coeruleus during sleepLydic R. and Baghdoyan H. Handbook of Behavioral State Control: Cellular and Molecular mechanisms, CRC Press, pp.195-211, 1999, 9780849331510
Chapitre d'ouvrage
hal-02372260
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Drug-induced versus non-pharmacological wakefulness: similar or different states? A whole brain analysis in TRAP2 transgenic mice2025
Pré-publication, Document de travail
hal-04934432
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Establishment of an optimized and automated workflow for whole brain probing of neuronal activity.2025
Pré-publication, Document de travail
hal-04942299
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Glutamatergic neurons in the lateral periaqueductal gray mediate wakefulness and REM sleep through different pathways2023
Pré-publication, Document de travail
hal-04311796
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