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Pierre Larraufie

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Transinteractome analysis reveals distinct niche requirements for isotype‐based plasma cell subsets in the bone marrow

Amélie Bonaud , Pierre Larraufie , Mélanie Khamyath , Ugo Szachnowski , Shaun M Flint
European Journal of Immunology, 2023, ⟨10.1002/eji.202250334⟩
Journal articles hal-04145276v1
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Regulation of enteroendocrine cell respiration by the microbial metabolite hydrogen sulfide

Pierre Larraufie , Kenza Haroun , Carla Fleury , Mireille Andriamihaja , François Blachier
Frontiers in Endocrinology, 2023, 14, ⟨10.3389/fendo.2023.1123364⟩
Journal articles hal-04120706v1
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Akkermansia muciniphila upregulates genes involved in maintaining the intestinal barrier function via ADP-heptose-dependent activation of the ALPK1/TIFA pathway

Camille Martin-Gallausiaux , Diego Garcia-Weber , Amandine Lashermes , Pierre Larraufie , Ludovica Marinelli
Gut microbes, 2022, 14 (1), pp.2110639. ⟨10.1080/19490976.2022.2110639⟩
Journal articles hal-03787581v2

The Human and Mouse Islet Peptidome: Effects of Obesity and Type 2 Diabetes, and Assessment of Intraislet Production of Glucagon-like Peptide-1

Sam Galvin , Richard Kay , Rachel Foreman , Pierre Larraufie , Claire Meek
Journal of Proteome Research, 2021, 20 (9), pp.4507-4517. ⟨10.1021/acs.jproteome.1c00463⟩
Journal articles hal-03449922v1
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Murine neuronatin deficiency is associated with a hypervariable food intake and bimodal obesity

Irene Cimino , Debra Rimmington , Y. C Loraine Tung , Katherine Lawler , Pierre Larraufie
Scientific Reports, 2021, 11 (1), pp.17571. ⟨10.1038/s41598-021-96278-8⟩
Journal articles hal-03449868v1
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Peptidomics of enteroendocrine cells and characterisation of potential effects of a novel preprogastrin derived-peptide on glucose tolerance in lean mice

Sam Galvin , Pierre Larraufie , Richard Kay , Haidee Pitt , Elise Bernard
Peptides, 2021, pp.170532. ⟨10.1016/j.peptides.2021.170532⟩
Journal articles hal-03208731v1
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Inhibition of mitochondrial function by metformin increases glucose uptake, glycolysis and GDF-15 release from intestinal cells

Yang Ming , Tamana Darwish , Pierre Larraufie , Debra Rimmington , Irene Cimino
Scientific Reports, 2021, 11 (2529), ⟨10.1038/s41598-021-81349-7⟩
Journal articles hal-03165371v1
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Production of hydrogen sulfide by the intestinal microbiota and epithelial cells and consequences for the colonic and rectal mucosa

Francois Blachier , Mireille Andriamihaja , Pierre Larraufie , Eunyeong Ahn , Annaig Lan
AJP - Gastrointestinal and Liver Physiology, 2021, 320 (2), pp.G125-G135. ⟨10.1152/ajpgi.00261.2020⟩
Journal articles hal-03033013v1
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Stimulation of motilin secretion by bile, free fatty acids, and acidification in human duodenal organoids

Emily L Miedzybrodzka , Rachel E Foreman , Van B Lu , Amy L George , Christopher A Smith
Molecular metabolism, 2021, 54, pp.101356. ⟨10.1016/j.molmet.2021.101356⟩
Journal articles hal-03449878v1
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Short Chain Fatty Acids – mechanisms and functional importance in the gut

Camille Martin-Gallausiaux , Ludovica Marinelli , Herve H. Blottiere , Pierre Larraufie , Nicolas Lapaque
Proceedings of the Nutrition Society, 2021, 80 (1), pp. 37-49. ⟨10.1017/S0029665120006916⟩
Journal articles hal-02536149v1

Ghrelin Does Not Directly Stimulate Secretion of Glucagon-like Peptide-1

Sara Lind Jepsen , Esben Thyssen Vestergaard , Pierre Larraufie , Fiona Mary Gribble , Frank Reimann
Journal of Clinical Endocrinology and Metabolism, 2020, 105 (1), pp.266-275. ⟨10.1210/clinem/dgz046⟩
Journal articles hal-03208849v1
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Organoid Sample Preparation and Extraction for LC-MS Peptidomics

Emily L Miedzybrodzka , Rachel E Foreman , Sam G Galvin , Pierre Larraufie , Amy L George
STAR Protocols, 2020, 1, ⟨10.1016/j.xpro.2020.100164⟩
Journal articles hal-03165408v1
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Secretin release after Roux-en-Y gastric bypass reveals a population of glucose-sensitive S cells in distal small intestine

Ida M Modvig , Daniel B Andersen , Kaare V Grunddal , Rune E Kuhre , Christoffer Martinussen
International Journal of Obesity, 2020, 44 (9), pp.1859 - 1871. ⟨10.1038/s41366-020-0541-7⟩
Journal articles hal-03165480v1
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Important Role of the GLP-1 Axis for Glucose Homeostasis after Bariatric Surgery

Pierre Larraufie , Geoffrey P Roberts , Anne K Mcgavigan , Richard G Kay , Joyce Li
Cell Reports, 2019, 26 (6), pp.1399-1408.e6. ⟨10.1016/j.celrep.2019.01.047⟩
Journal articles hal-03450982v1
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PYY plays a key role in the resolution of diabetes following bariatric surgery in humans

Claudia Guida , Sam D Stephen , Michael Watson , Niall Dempster , Pierre Larraufie
EBioMedicine, 2019, 40, pp.67 - 76. ⟨10.1016/j.ebiom.2018.12.040⟩
Journal articles hal-03451358v1

Acipimox Acutely Increases GLP-1 Concentrations in Overweight Subjects and Hypopituitary Patients

Esben Thyssen Vestergaard , Astrid Johanneson Hjelholt , Rune Kuhre , Niels Møller , Pierre Larraufie
Journal of Clinical Endocrinology and Metabolism, 2019, 104 (7), pp.2581-2592. ⟨10.1210/jc.2018-02503⟩
Journal articles hal-03450948v1
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Characterisation of proguanylin expressing cells in the intestine – evidence for constitutive luminal secretion

Florent Serge Dye , Pierre Larraufie , Richard Kay , Tamana Darwish , Juraj Rievaj
Scientific Reports, 2019, 9 (1), ⟨10.1038/s41598-019-52049-0⟩
Journal articles hal-03208847v1

Comparison of Human and Murine Enteroendocrine Cells by Transcriptomic and Peptidomic Profiling

Geoffrey P Roberts , Pierre Larraufie , Paul Richards , Richard G Kay , Sam G Galvin
Diabetes, 2019, 68 (5), pp.1062 - 1072. ⟨10.2337/db18-0883⟩
Journal articles hal-03208855v1
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Suppression of enteroendocrine cell glucagon-like peptide (GLP)-1 release by fat-induced small intestinal ketogenesis: a mechanism targeted by Roux-en-Y gastric bypass surgery but not by preoperative very-low-calorie diet

Ville Wallenius , Erik Elias , Erik Elebring , Bauke Haisma , Anna Casselbrant
Gut, 2019, 69, pp.1423 - 1431. ⟨10.1136/gutjnl-2019-319372⟩
Journal articles hal-03208843v1
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Abcc5 Knockout Mice Have Lower Fat Mass and Increased Levels of Circulating GLP‐1

Malgorzata Cyranka , Anna Veprik , Eleanor J Mckay , Nienke Loon , Amber Thijsse
Obesity, 2019, 27 (8), pp.1292 - 1304. ⟨10.1002/oby.22521⟩
Journal articles hal-03208852v1
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Single cell transcriptomic profiling of large intestinal enteroendocrine cells in mice – Identification of selective stimuli for insulin-like peptide-5 and glucagon-like peptide-1 co-expressing cells

Lawrence J Billing , Pierre Larraufie , Jo Lewis , Andrew Leiter , Joyce Li
Molecular metabolism, 2019, 29, pp.158-169. ⟨10.1016/j.molmet.2019.09.001⟩
Journal articles hal-03450647v1

Fructose malabsorption induces cholecystokinin expression in the ileum and cecum by changing microbiota composition and metabolism

Xufei Zhang , Alexandra Grosfeld , Edek Williams , Daniel Vasiliauskas , Sharon Barretto
FASEB Journal, 2019, 33 (6), pp.7126-7142. ⟨10.1096/fj.201801526RR⟩
Journal articles hal-02191008v1
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Butyrate produced by commensal bacteria down-regulates indolamine 2, 3-dioxygenase 1 (IDO-1) expression via a dual mechanism in human intestinal epithelial cells

Camille Martin-Gallausiaux , Pierre Larraufie , Anne Jarry , Fabienne F. Beguet-Crespel , Ludovica Marinelli
Frontiers in Immunology, 2018, 9, ⟨10.3389/fimmu.2018.02838⟩
Journal articles inserm-01937996v1
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Quantitative mass spectrometry for human melanocortin peptides in vitro and in vivo suggests prominent roles for β-MSH and desacetyl α-MSH in energy homeostasis

Peter Kirwan , Richard G Kay , Bas Brouwers , Vicente Herranz-Pérez , Magdalena Jura
Molecular metabolism, 2018, 17, pp.82-97. ⟨10.1016/j.molmet.2018.08.006⟩
Journal articles hal-03451378v1
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SCFAs strongly stimulate PYY production in human enteroendocrine cells

Pierre Larraufie , Camille Martin-Gallausiaux , Nicolas Lapaque , Joel Dore , F. M. Gribble
Scientific Reports, 2018, 8, pp.1-9. ⟨10.1038/s41598-017-18259-0⟩
Journal articles hal-02628091v1
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Mechanistic insights into the detection of free fatty and bile acids by ileal glucagon-like peptide-1 secreting cells

Deborah A Goldspink , Van B Lu , Lawrence J Billing , Pierre Larraufie , Gwen Tolhurst
Molecular metabolism, 2018, 7, pp.90-101. ⟨10.1016/j.molmet.2017.11.005⟩
Journal articles hal-03451396v1
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Co-storage and release of insulin-like peptide-5, glucagon-like peptide-1 and peptideYY from murine and human colonic enteroendocrine cells

Lawrence J Billing , Christopher A Smith , Pierre Larraufie , Deborah A Goldspink , Sam Galvin
Molecular metabolism, 2018, 16, pp.65-75. ⟨10.1016/j.molmet.2018.07.011⟩
Journal articles hal-03451387v1
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Liquid chromatography/mass spectrometry based detection and semi-quantitative analysis of INSL5 in human and murine tissues

R.G. G Kay , S. Galvin , P. Larraufie , F. Reimann , F.M. M Gribble
Rapid Communications in Mass Spectrometry, 2017, 31 (23), pp.1963-1973. ⟨10.1002/rcm.7978⟩
Journal articles hal-03451416v1
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Chylomicrons stimulate incretin secretion in mouse and human cells

Arianna Psichas , Pierre F Larraufie , Deborah A Goldspink , Fiona M Gribble , Frank Reimann
Diabetologia, 2017, 60 (12), pp.2475-2485. ⟨10.1007/s00125-017-4420-2⟩
Journal articles hal-03451408v1

The SNARE Protein Syntaxin-1a Plays an Essential Role in Biphasic Exocytosis of the Incretin Hormone Glucagon-Like Peptide 1

Sarah Wheeler , Holly Stacey , Yasaman Nahaei , Stephen Hale , Alexandre Hardy
Diabetes, 2017, 66 (9), pp.2327-2338. ⟨10.2337/db16-1403⟩
Journal articles hal-03451433v1
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TLR ligands and butyrate increase Pyy expression through two distinct but inter-regulated pathways

Pierre Larraufie , Joel Dore , Nicolas Lapaque , Herve Blottiere
Cellular Microbiology, 2017, 19 (2), ⟨10.1111/cmi.12648⟩
Journal articles hal-01530823v1

Angiotensin II Type 1 Receptor-Dependent GLP-1 and PYY Secretion in Mice and Humans

Ramona Pais , Juraj Rievaj , Pierre Larraufie , Fiona Gribble , Frank Reimann
Endocrinology, 2016, 157 (10), pp.3821-3831. ⟨10.1210/en.2016-1384⟩
Journal articles hal-03451442v1

Rab35 GTPase Triggers Switch-like Recruitment of the Lowe Syndrome Lipid Phosphatase OCRL on Newborn Endosomes

Clothilde Cauvin , Morgane Rosendale , Neetu Gupta-Rossi , Murielle Rocancourt , Pierre Larraufie
Current Biology - CB, 2016, 26 (1), pp.120-128. ⟨10.1016/j.cub.2015.11.040⟩
Journal articles hal-02431336v1
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Functional metagenomics to decipher food-microbe-host crosstalk

Pierre Larraufie , Tomas de Wouters , Gabrielle Veronese , Herve M. Blottiere , Joel Dore
Proceedings of the Nutrition Society, 2015, 74 (1), pp.1-4. ⟨10.1017/S0029665114001566⟩
Journal articles hal-01183892v1