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Pierre Sibille

72
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Presentation

Titulaire d'un doctorat en Immunologie j'exerce depuis 1997 dans le domaine des interactions Hôte-pathogène. Depuis maintenant 10 ans, mes activités de recherche concernent l'étude eds déterminants structuraux qui gouvernent le tropisme de différentes souches de prions. Mon expertise concerne principalement l'immunologie, la biochimie et la biophysique des interactions hôte-pathogène

Publications

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Prion strain-dependent tropism is maintained between spleen and granuloma and relies on lymphofollicular structures

Iman Al-Dybiat , Mohammed Moudjou , Davy Martin , Fabienne Reine , Laetitia Herzog
Scientific Reports, 2019, 9 (1), 14 p. ⟨10.1038/s41598-019-51084-1⟩
Journal articles hal-02627362v1
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Prion Strains and Transmission Barrier Phenomena

Angelique Egalon , Vincent Béringue , Human Rezaei , Pierre Sibille
Pathogens, 2018, 7 (1), ⟨10.3390/pathogens7010005⟩
Journal articles hal-02626379v1
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Glycoform-independent prion conversion by highly efficient, cell-based, protein misfolding cyclic amplification

Mohammed M. Moudjou , Jerome Chapuis , Meriem Mekrouti , Fabienne Reine , Laetitia Herzog
Scientific Reports, 2016, 6, ⟨10.1038/srep29116⟩
Journal articles hal-02629949v1

Interaction between Shadoo and PrP Affects the PrP-Folding Pathway

Danica Ciric , Charles-Adrien Richard , Mohammed Moudjou , Jérôme Chapuis , Pierre Sibille
Journal of Virology, 2015, 89 (12), pp.6287-6293. ⟨10.1128/JVI.03429-14⟩
Journal articles hal-02636090v1

Existence of conventional dendritic cells in Gallus gallus revealed by comparative gene expression profiling

- Thien-Phong Vu Manh , Hélène Marty , Pierre Sibille , Yves Le Vern , Bernd Kaspers
Journal of Immunology, 2014, 192 (10), pp.4510-4517. ⟨10.4049/jimmunol.1303405⟩
Journal articles hal-02640822v1
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Highly infectious prions generated by a single round of microplate-based protein misfolding cyclic amplification

Mohammed M. Moudjou , Pierre Sibille , Guillaume Fichet , Fabienne Reine , Jerome Chapuis
mBio, 2014, 5 (1), ⟨10.1128/mBio.00829-13⟩
Journal articles hal-02636078v1
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Highly Infectious Prions Generated by a Single Round of Microplate-Based Protein Misfolding Cyclic Amplification

Mohammed Moudjou , Pierre Sibille , Guillaume Fichet , Fabienne Reine , Jérôme Chapuis
mBio, 2014, 5 (1), ⟨10.1128/mBio.00829-13⟩
Journal articles hal-03402322v1
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Quaternary Structure of Pathological Prion Protein as a Determining Factor of Strain-Specific Prion Replication Dynamics

Florent Laferrière , Philippe Tixador , Mohammed Moudjou , Jérôme Chapuis , Pierre Sibille
PLoS Pathogens, 2013, 9 (10), ⟨10.1371/journal.ppat.1003702⟩
Journal articles hal-03402326v1

Presence of dendritic cells in chicken spleen cell preparations and their functional interaction with the parasite Toxoplasma gondii

Pascale P. Quéré , Josette Pierre , My Dung Hoang , Evelyne Esnault , Jorge Domenech
Veterinary Immunology and Immunopathology, 2013, 153 (1-2), pp.57-69. ⟨10.1016/j.vetimm.2013.02.007⟩
Journal articles hal-02648390v1
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Quaternary structure of pathological prion protein as a determining factor of strain-specific prion replication dynamics

Florent Laferrière , Philippe Tixador , Mohammed M. Moudjou , Jerome Chapuis , Pierre Sibille
PLoS Pathogens, 2013, 9 (10), ⟨10.1371/journal.ppat.1003702⟩
Journal articles hal-02650542v1
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Automatisation de l'analyse des images et du traitement des données produites à l'aide des logiciels ImageJ et Excel ®

Jérôme Chapuis , Nicolas Pons , Philippe Tixador , Pierre Sibille
Cahier des Techniques de l'INRA, 2012, 76, pp.31-42
Journal articles hal-04237187v1

Facilitated cross-species transmission of prions in extraneural tissue

Vincent Béringue , Laetitia Herzog , Emilie Jaumain , Fabienne Reine , Pierre Sibille
Science, 2012, 335 (6067), pp.472-475. ⟨10.1126/science.1215659⟩
Journal articles hal-01019814v1

Cloning, expression and functional characterization of chicken CCR6 and its ligand CCL20

Iciar Munoz , Magali Berges , Claire Bonsergent , Fleur Aline , Pascale P. Quéré
Molecular Immunology, 2009, 47 (2-3), pp.551-559. ⟨10.1016/j.molimm.2009.07.010⟩
Journal articles hal-02656782v1

Excretory-secretory products of larval Fasciola hepatica investigated using a two-dimensional proteomic approach

Benjamin Gourbal , Frédéric Guillou , G. Mitta , Pierre Sibille , A. Théron
Molecular and Biochemical Parasitology, 2008, 161 (1), pp.63-66. ⟨10.1016/j.molbiopara.2008.05.002⟩
Journal articles halsde-00332385v1
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La microflore digestive des volailles : facteurs de variation et conséquences pour l'animal

Irène Gabriel , S. Mallet , Pierre Sibille
Productions Animales, 2005, 18 (5), pp.309-322
Journal articles hal-02681958v1

Preface - Hypodermosis in China, Eu and Central Asia

C. Boulard , Guanlin He , Pierre Sibille , H. Yin
Chinese Journal of Veterinary Parasitology, 2004, 12 (suppl.), n.p
Journal articles hal-02671965v1

Deer myiasis in France

S. Maes , Pierre Sibille , C. Boulard
Chinese Journal of Veterinary Parasitology, 2004, 12 (suppl.), pp.123-131
Journal articles hal-02681898v1
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Early and transient cytotoxic response of peritoneal cells from Fasciola hepatica-infected rats

Pierre Sibille , Omar Tliba , Chantal Boulard
Veterinary Research, 2004, 35, pp.573-584
Journal articles hal-02675045v1
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Early and transient cytotoxic response of peritoneal cells from Fasciola hepatica-infected rats

Pierre Sibille , Omar Tliba , Chantal Boulard
Veterinary Research, 2004, 35 (5), pp.573-584. ⟨10.1051/vetres:2004033⟩
Journal articles hal-00902797v1

Control of cattle grub in Europe

Pierre Sibille , C. Boulard
Chinese Journal of Veterinary Parasitology, 2004, 12 (suppl.), pp.106-110
Journal articles hal-02672415v1
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Evaluation of the hepatic NK cell response during the early phase of Fasciola hepatica infection in rats

O. Tliba , A. Chauvin , Yves Le Vern , C. Boulard , Pierre Sibille
Veterinary Research, 2002, 33, pp.327-332
Journal articles hal-02677079v1

Early hepatic cytokine mRNA expression in experimental rat fasciolosis

O. Tliba , Pierre Sibille , C. Boulard , A. Chauvin
Veterinary Parasitology, 2002, 103 (3), pp.237-349
Journal articles hal-02673017v1
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Early hepatic immune response in rats infected with Fasciola hepatica

O. Tliba , Nathalie Moiré , Yves Le Vern , C. Boulard , A. Chauvin
Veterinary Research, 2002, 33, pp.261-270
Journal articles hal-02676863v1

Fasciola hepatica: influence of gender and liver biotransformations on flukicide treatment efficacy of rats infested and cured with either clorsulon/ivermectin or Triclabendazole

Pierre Sibille , Cécile Calléja , Florence Carreras , K. Bigot , Pierre Galtier
Experimental Parasitology, 2000, 94, pp.227-237
Journal articles hal-02694634v1

Use of an enzyme-linked lectinsorbent assay to monitor the shift in polysaccharide composition in bacterial biofilms

V. Leriche , Pierre Sibille , B. Carpentier
Applied and Environmental Microbiology, 2000, 66 (5), pp.1851-1856
Journal articles hal-02698447v1
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Local hepatic immune response in rats during primary infection with Fasciola hepatica

O. Tliba , Pierre Sibille , C. Boulard , A. Chauvin
Parasite, 2000, 7 (1), pp.9-18. ⟨10.1051/parasite/2000071009⟩
Journal articles hal-02696964v1

Comparison of hepatic and renal drug-metabolising enzyme activities in sheep given single or two-fold challenge infections with Fasciola hepatica

Cécile Calléja , K. Bigot , C. Eeckhoutte , Pierre Sibille , C. Boulard
International Journal for Parasitology, 2000, 30 (8), pp.953-958
Journal articles hal-02695314v1

Mimotopes of polyreactive anti-DNA antibodies identified using phage-display peptide libraries

Pierre Sibille , Thérèse Ternynck , Faridabano Nato , Gérard Buttin , Donny Strosberg
European Journal of Immunology, 1997, 27 (5), pp.1221-1228. ⟨10.1002/eji.1830270525⟩
Journal articles hal-02696137v1

A FIV epitope defined by a phage peptide library screened with a monoclonal anti-FIV antibody

Pierre Sibille , a D Strosberg
Immunology Letters, 1997, 59 (3), pp.133-137. ⟨10.1016/S0165-2478(97)00111-9⟩
Journal articles hal-02699260v1

Comparison of serological tests for the diagnosis of feline immunodeficiency virus infection of cats

Pierre Sibille , A. Avrameas , A. Moraillon , Jennifer Richardson , P. Sonigo
Veterinary Microbiology, 1994, 45, pp.259-267
Journal articles hal-02706916v1

Characterising structural heterogeneity of prions

Agnes Le Saux , Vincent Béringue , Human Rezaei , Jan Bohl , Angélique Igel-Egalon
4e réunion plénière du GDR Médyna (, GDR Médyna, Oct 2023, Kerjouanno, Morbihan, France
Conference papers hal-04236129v1
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Caractérisation de l’hétérogénéité structurale des prions

Agnès Le Saux , Vincent Béringue , Human Rezaei , Jan Bohl , Angélique Igel-Egalon
8ème Journée d’actualité sur les maladies à prions et autres protéinopathies, Jun 2023, Paris, France
Conference papers hal-04217152v1

Prion species barriers: studies with atypical scrapie and prions from pure synthetic origin

Vincent Béringue , Laetitia Herzog , Fabienne Reine , Naima Aron , Joan Torrent
7th Iberian Congress on Prions, Dec 2021, Jaca, Spain
Conference papers hal-04502258v1
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Prion strain evolution and adaptation

Pierre Sibille , Vincent Béringue
Prion 2018, May 2018, Santiago de Compostella, Spain
Conference papers hal-04236401v1

CCL20 production by Eimeria tenella infected chicken epithelial cells: a new mechanism to control the infection?

Françoise Bussière , Alisson Niepceron , Yves Le Vern , Alix Sausset , Sonia Lamandé
34. Congrès du club d'étude des cellules épithéliales digestives (CECED), Mar 2017, Paris, France
Conference papers hal-01602314v1

PrP glycosylation-independent amplification of prions using highly efficient cell-based protein misfolded cyclic amplification

Mohammed M. Moudjou , Jerome Chapuis , Meriem Mekrouti , Fabienne Reine , Laetitia Herzog
Prion, Institut National de la Recherche Agronomique (INRA). FRA., 2016, PHILADELPHIA, United States. pp.1
Conference papers hal-02738985v1

CCL20 production by Eimeria tenella infected chicken epithelial cells: a new mechanism to control the infection ?

Françoise Bussière , Marion Vergonjeanne , Alisson Niepceron , Sonia Lacroix Lamandé , Anne Silvestre
5. Journées d'animation scientifique de la FéRI, Fédération de recherche en infectiologie (FéRI)., Jul 2016, Tours, France
Conference papers hal-02794437v1
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Highly infectious prions generated by a single round of microplate-based protein misfolding cyclic amplification

Mohammed M. Moudjou , Pierre Sibille , Guillaume Fichet , Fabienne Reine , Jerome Chapuis
International Prion Congress 2014, May 2014, Trieste, Italy. ⟨10.4161/pri.29370⟩
Conference papers hal-02739413v1

Characterization of chicken adherent spleen cells and functional interaction with Toxoplasma gondii protozoan

Pascale P. Quéré , Josette Pierre , My Dung Hoang , Evelyne Esnault , Jorge Domenech
12. Avian Immunology Research Group Meeting (AIRG2012), BBSRC Roslin Institute. Edinburgh, GBR., Aug 2012, Edinburgh, United Kingdom. pp.36
Conference papers hal-02749918v1

Antibody response to H5N9 inactivated vaccine and MHC diversity in the chicken

Pascale P. Quéré , Pierre Sibille , Nicolas N. Bruneau , T.X. T.X. Toan , J.C. J.C. Maillard
8. Journées du réseau francophone d'Immunologie des Animaux Domestiques (IAD), May 2011, Marcy l'Etoile, France. pp.20
Conference papers hal-01001392v1

Production de la chimiokine aviaire CCL20 en système CELO et potentiel adjuvant en liaison avec un fragment de l'hémagglutinine du virus influenza aviaire

Claire Bonsergent , Pierre Sibille , C. Bernard , Valérie Labas , Patrick Langlois
7. Rencontre du Réseau d'Immunologie des Animaux Domestiques (IAD), May 2010, Maisons-Alfort, France. 1 p
Conference papers hal-02816430v1

Antibody response to H5N9 inactivated vaccine and MHC diversity in the chicken

Bertrand B. Bed'Hom , Pascale P. Quéré , Pierre Sibille , Magalie Bergès , Nicolas N. Bruneau
XIth Meeting of the Avian Immunology Research Group, 2010, Budapest, Hungary
Conference papers hal-02817298v1

Cellules dendritiques spléniques aviaires : résultats préliminaires d'isolement et de caractérisation

Pascale Quere , Josette Pierre , Patrick Langlois , Pierre Sibille , Isabelle Dimier
Journée d'Animation du Réseau Immunologie des Animaux Domestiques (IAD), Oct 2008, Nouzilly, France. 1 p
Conference papers hal-02823981v1

Le niveau de la réponse vaccinale au virus influenza est déterminé par le génotype au CMH chez la poule

Bertrand B. Bed'Hom , Nicolas N. Bruneau , Magali Berges , Pascale P. Quéré , Pierre Sibille
Journées Scientifiques du Département Génétique Animale, 2008, Lacanau, France. 1 p
Conference papers hal-02814827v1

Characterization of chicken splenic dendritic cells and enrichment protocol to develop cell lines : preliminary results

Pascale P. Quéré , Josette Pierre , Patrick Langlois , Pierre Sibille , Isabelle Dimier-Poisson
Journée d'Animation du Réseau Immunologie des Animaux Domestiques (IAD), Oct 2008, Nouzilly, France. pp.Inconnu
Conference papers hal-02824031v1

Le niveau de la réponse vaccinale au virus influenza est déterminé par le génotype au CMH chez la poule.

Bertrand B. Bed'Hom , Nicolas N. Bruneau , Magali Berges , Pascale Quere , Pierre Sibille
Journées Scientifiques, Département de Génétique Animale, Apr 2008, Lacanau
Conference papers hal-02751210v1

Cloning, expression and functional characterization of chicken CCR6 and its ligand CCL20

I. Munoz , Pascale P. Quéré , Pierre Sibille
Journée d'Animation du Réseau Immunologie des Animaux Domestiques (IAD), Oct 2008, Nouzilly, France. 1 p
Conference papers hal-02812923v1

Cloning, expression and functional characterization of chicken CCR6 and its ligand CCL20

I Munoz , Pascale P. Quéré , Pierre Sibille
10th Avian Immunology Research Group Conference, 2008, Gold Coast, Australia. 1 p
Conference papers hal-02813554v1

Clonage moléculaire et caractérisation de la chimiokine CCL20 et de son récepteur CCR6 chez le poulet

I Munoz , Pierre Sibille , Pascale P. Quéré
Journées d’Animation Scientifique du Département de Santé Animale, 2007, Tours, France. pp.Inconnu
Conference papers hal-02813177v1

Do Digenean parasites use different or common strategies to escape intermediate and definitive host's immune response?, session 1 "From innate to adaptive immunity"

Pierre Sibille , Christine Coustau
2nd European Veterinary Immunology Workshop, Sep 2006, Paris, France
Conference papers hal-02752776v1

Immune modulation by newly excysted juveniles of Fasciola hepatica

O. Tliba , E. Khaznadji , M. Sabau , Nathalie Moiré , Pierre Sibille
5. Framework, Mar 2004, Bordeaux, France
Conference papers hal-02762234v1

Control of cattle grub in Europe

Pierre Sibille , C. Boulard
Hypodermosis in China, EU and Central Asia, Oct 2004, Lanzhou, China
Conference papers hal-02828450v1

Création sur le centre Inra de Tours-Nouzilly d'une nouvelle animalerie en confinement P3 destinée aux ruminants et aux souris infectés par les agents des ESST ou par d'autres pathogènes

Frédéric F. Lantier , Pierre Sibille
3. Séminaire sur les Recherches engagées à l'INRA sur les ESST et les Prions, Feb 2003, Le Croisic, France. n.p
Conference papers hal-02825917v1

Early hepatic immune response in Fasciola hepatica infected rats

O. Tliba , Pierre Sibille , C. Boulard , A. Chauvin
6. International Veterinary Immunology Symposium, Jul 2001, Uppsala, Sweden
Conference papers hal-02762023v1

Deer myiasis in France

S. Maes , Pierre Sibille , C. Boulard
Hypodermosis in China, EU and Central Asia, Oct 2001, Lanzhou, China
Conference papers hal-02827738v1

Preface - Hypodermosis in China, Eu and Central Asia

C. Boulard , Guanlin He , Pierre Sibille , H. Yin
Hypodermosis in China, EU and Central Asia, Oct 2001, Lanzhou, China
Conference papers hal-02830118v1

Isolation of an immunosuppressive fraction of adult F. hepatica excretion/secretion products using a Galanthus nivalis agglutinin

Pierre Sibille , A. Chauvin
6. International Veterinary Immunology Symposium, Jul 2001, Uppsala, Sweden
Conference papers hal-02761938v1

La démarche qualité recherche à la PAP

Ginette Dambrine , M.C. Fauré , Pierre Sibille
1. Rencontres de la qualité en recherche, Mar 2000, Draveil, France
Conference papers hal-02769860v1

Réalisation d'une banque soustractive entre les stades juvéniles nouvellement excystés et adultes du parasite Fasciola hepatica

E. Khaznadji , Nathalie Moiré , Pierre Sibille , Florence Carreras , C. Boulard
Forum de l'école doctorale, May 2000, Tours, France
Conference papers hal-02770096v1

Quantification des ARNm de cytokines chez le rat infesté expérimentalement par Fasciola hepatica (phase précoce)

O. Tliba , Pierre Sibille , C. Boulard , A. Chauvin , . Université de Tours
Forum de l'école doctorale, May 2000, Tours, France
Conference papers hal-02769314v1

Caractérisation des ARNm des cytokines libérées localement durant la phase d'une infestation expérimentale par F. hepatica chez le rat

O. Tliba , Pierre Sibille , C. Boulard , A. Chauvin
Congrès Annuel de la Société Française d'Immunologie, Nov 2000, Paris, France. pp.149
Conference papers hal-02837984v1

Prion strain-dependent tropism is maintained between spleen and granuloma and relies on lymphofollicular structures

Iman Al-Dybiat , Mohammed Moudjou , Fabienne Reine , Laetitia Herzog , Patricia Berthon
11. Symposium of the French Domestic Animal Immunology Network (IAD 2018), Mar 2018, Tours, France. , 56 p., 2018
Conference poster hal-02737597v1

CCL20 production by Eimeria tenella infected chicken epithelial cells: a new mechanism to control the infection ?

Françoise Bussière , Alisson Niepceron , Sonia Lacroix Lamandé , Pierre Sibille , Pascale Quéré
14. Avian Immunology Research Group (AIRG) Meeting 2016, Sep 2016, Herrsching am Ammersee, Germany. , 120 p., 2016
Conference poster hal-02739230v1

Conventional dendrtitic cells are present in the chicken

Pascale P. Quéré , Thien-Phong Vu Manh , Hélène Marty , Yves Le Vern , Pierre Sibille
13. International Symposium on Dendritic Cells, Sep 2014, Tours, France. 2014, DC 2014
Conference poster hal-02739720v1

Size, not density of strain-specific prion particles determines their replication dynamics

Florent Lafferiere , Philippe Tixador , Mohammed M. Moudjou , Jerome Chapuis , Pierre Sibille
PRION 2013: Conquering Frontiers, May 2013, Banff, Alberta, Canada. Landes Bioscience, Prion, 7 (Suppl.), 2013
Conference poster hal-02748301v1

Digenean parasites use common strategies to avoid intermediate and definitive hosts immune response

Pierre Sibille , Christine Coustau
16. European Congress of Immunology, Sep 2006, Paris, France. 1 p., 2006
Conference poster hal-02814517v1

Early transient cytotoxic response of peritoneal cells from Fasciola hepatica-infected rats

Pierre Sibille , O. Tliba , Chantal Boulard
European Workshop in Veterinary Immunology, Sep 2006, Paris, France. 1 p., 2006
Conference poster hal-02812415v1

Habilitation à diriger les recherches

Pierre Sibille
Sciences du Vivant [q-bio]. 2002
Habilitation à diriger des recherches tel-02831273v1
Image document

Prions and Lymphocompetency

Pierre Sibille
Master. Neurofrontiers III, Concepcion, Chile. 2023
Lectures hal-04236406v1
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The prion paradigm and structural information transfer

Pierre Sibille
Master. UE d'épigénétique, Paris, France. 2020
Lectures hal-04236436v1