
Pierre-Yves renard
185
Documents
Publications
Publications
Multi-target drug Ligands design and synthesis for Alzheimer disease backed by X-ray crystal analysesAnnual Conference of AnalytiX (7, 2019), Nov 2019, Berlin, Germany
Communication dans un congrès
hal-02404227
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Sondes pro-fluorescentes et chémiluminescentes pour la détection d'analyses d'intérêt biologiqueSéminaire national, Institut Brestois Santé Agro Matière (IBSAM), May 2019, Brest, France
Communication dans un congrès
hal-02404291
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Chimiluminescence in vivoRencontre ChiMi. Fluorescence : de la paillasse à l'utilisation clinique, Jan 2018, Dijon, France
Communication dans un congrès
hal-02395824
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Sondes fluorogéniques pour la détection d'activités enzymatiques et d'analytes d'intérêt biologiquesSéminaire national, Institut des biomolécules Max Mousseron (IBMM, UMR 5247), Oct 2018, Montpellier, France
Communication dans un congrès
hal-02393849
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Overview of 3-hydroxy-pyridindaldoxime based reactivatorsInternational workshop on nerve agents, North Atlantic Treaty Organisation (NATO), Nov 2018, Paris, France
Communication dans un congrès
hal-02403935
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Réactions de ligation fluorogéniquesJournées scientifiques de chémobiologie, Nov 2018, Lille, France
Communication dans un congrès
hal-02389306
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Méthode de criblage : identification de catalyseurs de la réaction de Diels-AlderJournée scientifique du LabEx Chimie des Architectures Moléculaires Multifonctionnelles et des Matériaux (CHARMMMAT, 6, 2018)), Jun 2018, Cachan, France
Communication dans un congrès
hal-03098307
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Fluorogenic Behaviour of the Hetero-Diels-Alder Ligation of 5-Alkoxyoxazoles with Maleimides and their ApplicationsInternational Caparica Conference on Chromogenic and Emissive Materials (3, 2018), Jun 2018, Lisbonne, Portugal
Communication dans un congrès
hal-02388673
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Pro-fluorescent and chemiluminescent probes for enzymatic activities detectionSéminaire national, Laboratoire des biomolécules (LBM, UMR 7203), May 2018, Paris, France
Communication dans un congrès
hal-02393089
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Méthode de criblage : identification de catalyseurs de la réaction de Diels-AlderJournée scientifique du LabEx Chimie des Architectures Moléculaires Multifonctionnelles et des Matériaux (CHARMMMAT, 6, 2018)), Jun 2018, Cachan, France
Communication dans un congrès
hal-02372510
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The effects of organophosphorus compounds and novel antidotes on human neuronal cellsInternational Symposium on Cholinergic Mechanisms (ISCM, 15, 2016), Oct 2016, Marseille, France. pp.224-225
Communication dans un congrès
hal-02024991
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Selective and sensitive near-infrared fluorescent probe for acetylcholinesterase imagingInternational Symposium on Cholinergic Mechanisms (ISCM, 15, 2017), Oct 2016, Marseille, France. pp.209, ⟨10.1111/jnc.13925⟩
Communication dans un congrès
hal-02024977
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Hupresin, a new affinity resin to purify butyrylcholinesteraseInternational Symposium on Cholinergic Mechanisms (ISCM, 15, 2017), Oct 2016, Marseille, France. pp.210, ⟨10.1111/jnc.13925⟩
Communication dans un congrès
hal-02024979
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Novel centrally active antidote for intoxication by sarin and VX nerve agentsCongress of the Federation-of-European-Biochemical-Societies (FEBS) on From Molecules to Cells and Back (42, 2017), Sep 2017, Jérusalem, Israel. pp.242, ⟨10.1111/febs.14174⟩
Communication dans un congrès
hal-02024992
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Toward an innovative treatment of Alzheimer's disease: Synthesis and evaluation of multi-target directed ligands (MTDLs) targeting acetylcholinesterase (AChE) and alpha7 nicotinic acetylchloline receptors (alpha7 nAChRs)International Symposium on Cholinergic Mechanisms (ISCM, 15, 2016), Oct 2016, Marseille, France. pp.209-210
Communication dans un congrès
hal-02024978
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L'acétylcholinestéraseSéminaire industriel, Servier, Mar 2016, Croissy-sur-Seine, France
Communication dans un congrès
hal-02391648
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Heterotrifunctionnal linkers for bioconjugate reactionsThe Missing link biologically driven ligation of carbohydrates and proteins, Jun 2016, Kiel, Germany
Communication dans un congrès
hal-02389804
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Exemples d'utilisation de sondes fluorescentes pour détecter l'évolution et les impacts de traitements antitumorauxJournée de présentation et d´échanges Chimie, Biologie et Cancer dans l´inter-région Nord-Ouest, Apr 2016, Amiens, France
Communication dans un congrès
hal-02395831
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New oximes for OP poisoned cholinesterases reactivationInternational workshop on chemical warfare agents: toxicity, emergency response and medical countermeasures, Sep 2016, Paris, France
Communication dans un congrès
hal-02388800
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Dynamic mapping of acetylcholinesterase for structural-dynamics based reactivator design12th International Meeting on Cholinesterases, Sep 2015, Elche, Spain
Communication dans un congrès
hal-02024984
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Water soluble unsymmetrical sulfoxanthene dyes - access to a novel class of broad spectrum dark quenchersInternational Caparica Conference on Chromogenic and Emissive Materials (2, 2016), Sep 2016, Lisbonne, Portugal
Communication dans un congrès
hal-02388670
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Pro-fluorescent and chemiluminescent probes for enzymatic activities detectionSéminaire national, Institut de chimie de Nice (ICN, UMR 7272), Mar 2016, Nice, France
Communication dans un congrès
hal-02393073
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Insights on two in situ click chemistry reactions for the synthesis of AChE inhibitorsInternational Meeting on Cholinesterases - Sixth International Conference on Paraoxonases (12, 2015), Sep 2015, Elche, Spain
Communication dans un congrès
hal-02379142
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L'acétylcholinestérase : une enzyme modèle pour le chimiste bio-organicienSéminaire national, Institut de chimie moléculaire de l'Université de Bourgogne (ICMUB, UMR 6302), Apr 2015, Dijon, France
Communication dans un congrès
hal-02391659
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Evaluation of three novel hydroxypicolinaldehyde oximes as efficient uncharged reactivators of VX-inhibited human acetylcholinesteraseFEBS-EMBO Anniversary Conference, Federation of European Biochemical Societies, Aug 2014, Paris, France. pp.65, ⟨10.1111/febs.12919⟩
Communication dans un congrès
hal-02395537
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Synthesis and in vitro and in vivo evaluations of New Uncharged reactivators for cholinesterases inhibited by organophosphorus nerve agentsMedical Chemical Defense Conference (MCDC, 17, 2019), Mar 2019, Munich, Germany
Poster de conférence
hal-02543452
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Development of chemiluminescent probes for enzymatic activity detection.Journées du Groupement de recherche agents d'imagerie moléculaire (GDR AIM, 2, 2019), May 2019, Dijon, France
Poster de conférence
hal-02556313
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Synthesis and evaluations of uncharged reactivators for cholinesterases inhibited by organophosphate agentsInternational Conference on Chemical Biological Radiological and Nuclear agents (CBRN) - Research & Innovation (3, 2019), May 2019, Nantes, France
Poster de conférence
hal-02543439
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Development of miniaturized fluorescence-based device for mycotoxin detectionRencontres en chimie organique biologique (RECOB, 17, 2018), Mar 2018, Aussois, France
Poster de conférence
hal-02556310
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Development of chemiluminescent probes for enzymatic activity detection.Journées du Groupement de recherche agents d'imagerie moléculaire (GDR AIM, 1, 2018), Jun 2018, Orléans, France
Poster de conférence
hal-02556312
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Development of a caspase-3 probe for apoptosis detection by dual optical-nuclear imagingRencontre ChiMi. Fluorescence : de la paillasse à l'utilisation clinique, Jan 2018, Dijon, France
Poster de conférence
hal-02556303
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Development of miniaturized fluorescence-based device for mycotoxin detectionJournée de l’Ecole doctorale normande de chimie (JEDNC, 2018), Jun 2018, Rouen, France
Poster de conférence
hal-02556309
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Uncharged reactivators of cholinesterases inhibited by organophosphorus nerve agents.International Meeting on Cholinesterases (13, 2018) and International Conference on Paraoxonases (7, 2018)), Sep 2018, Hradec Králové, Czech Republic
Poster de conférence
hal-02543467
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Development of miniaturized fluorescence-based device for mycotoxin detectionJournée Nord-Ouest Européennes des Jeunes Chercheurs et du Groupe Français des Polymères Grand Ouest (JNOEJC), Jun 2017, Caen, France
Poster de conférence
hal-02556308
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Development of a caspase-3 probe for apoptosis detection by dual optical-nuclear imagingJournées de l’Ecole doctorale normande Biologie Intégrative, Santé, Environnement (EdN BISE, 20, 2017), Mar 2017, Le Havre, France
Poster de conférence
hal-02556299
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New Uncharged reactivators for cholinesterases inhibited by organophosphorus nerve agentsInternational Conference on Chemical Biological Radiological nuclear Explosive - Research & Innovation (CBRNE, 2, 2017), May 2017, Lyon, France
Poster de conférence
hal-02544823
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Development of miniaturized fluorescence-based device for mycotoxin detectionJournée de l’Ecole doctorale normande de chimie (JEDNC, 2017), Jun 2017, Rouen, France
Poster de conférence
hal-02556306
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Development of chemiluminescent probes for enzymatic activity detection.Anglo-Norman colloquium on organic chemistry (ANORCQ, 13, 2016), Apr 2016, Rouen, France
Poster de conférence
hal-02556286
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Development of chemiluminescent probes for enzymatic activity detection.Journée de l’Ecole doctorale normande de chimie (JEDNC, 2016), Jun 2016, Caen, France
Poster de conférence
hal-02556287
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Multi Target directed ligands for the treatment of Alzheimer’s diseaseRencontres internationales de chimie thérapeutique (RICT, 52, 2016), Jul 2016, Caen, France
Poster de conférence
hal-02544849
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Development of chemiluminescent probes for enzymatic activity detection.International Caparica Conference on Chromogenic and Emissive Materials (I3CEM, 2, 2016), Sep 2016, Lisbonne, Portugal
Poster de conférence
hal-02556284
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Development of a caspase-3 probe for apoptosis detection by dual optical-nuclear imagingInternational Caparica Conference on Chromogenic and Emissive Materials (I3CEM, 2, 2016), Sep 2016, Lisbonne, Portugal
Poster de conférence
hal-02556296
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Development of a caspase-3 probe for apoptosis detection bu dual optical-nuclear imagingChemical Biology Symposium, Dec 2016, Paris, France
Poster de conférence
hal-01663935
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Selective and Sensitive Near-Infrared Fluorescent Probe for Acetylcholinesterases ImagingInternational Symposium on Cholinergic Mechanisms (ISCM, 15, 2016), Oct 2016, Marseille, France
Poster de conférence
hal-02544874
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Development of chemiluminescent probes for enzymatic activity detection.PSL Chemical Biology Symposium, Dec 2016, Paris, France
Poster de conférence
hal-02556279
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Development of a caspase-3 probe for apoptosis detection by dual optical-nuclear imagingJournées de l’Ecole doctorale normande Biologie Intégrative, Santé, Environnement (EdN BISE, 19, 2016), Mar 2016, Caen, France
Poster de conférence
hal-02556291
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Development of a caspase-3 probe for apoptosis detection bu dual optical-nuclear imagingIC3EM, Sep 2016, Caparica, Portugal
Poster de conférence
hal-01663947
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Synthesis of new uncharged reactivators for cholinesterases inhibited by organophosphorus nerve agentsTetrahedron Symposium (17, 2016), Jun 2016, Barcelone, Spain
Poster de conférence
hal-02544884
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Design and Development of New Uncharged Reactivators of OP-Inhibited CholinesterasesInternational Conference on Chemical Biological Radiological and Nuclear agents (CBRN) - Research & Innovation (1, 2015), Mar 2015, Antibes, France
Poster de conférence
hal-02544917
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Uncharged Reactivators of cholinesterases Inhibited by organophosphorus nerve agentsInternational Meeting on Cholinesterases - Sixth International Conference on Paraoxonases (12, 2015), Sep 2015, Elche, Spain
Poster de conférence
hal-02544902
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Phosphoryl compoundsBest Synthetic Methods: Organophosphorus (V), Academic press, pp.365-562, 2014, 978-0-08-098212-0. ⟨10.1016/C2011-0-04165-0⟩
Chapitre d'ouvrage
hal-02345183
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Preparation of new nucleophile-reactive sulfonated compounds for the radiolabeling of biomolecules; precursors and conjugates thereofFrance, Patent n° : WO 2014079979. 2014
Brevet
hal-01150298
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Composition and methods for the purification and production of butyrylcholinesterase.France, Patent n° : PCT/US14/66373. 2014
Brevet
hal-01150306
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Heterotetrafunctional reagents for bioconjugate chemistryFrance, Patent n° : EP14 50478. 2014
Brevet
hal-01150305
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Novel uncharged reactivators against OP-inhibition of human acetylcholinesteraseFrance, Patent n° : EP13306584.7. 2013
Brevet
hal-01150304
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Preparation of 7,11-Methanocycloocta[b]quinoline derivative as highly functionalizable acetylcholinesterase inhibitors for treating neurological diseasesFrance, Patent n° : WO 2011124712 A1. 2011
Brevet
hal-01150301
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Labeled huprine derivatives and their use in medical imagingFrance, Patent n° : WO 2011124713 A1. 2011
Brevet
hal-01150300
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