Pierre-Yves renard

184

Documents

Publications

	Light-Induced Unlocking Reactivity of Fragments for Fast Target-Guided Synthesis of Carbonic Anhydrase Inhibitors Chloé Puteaux , Isabelle Toubia , Lina Truong , Marie Hubert-Roux , Laetitia Bailly Angewandte Chemie International Edition, 2024, 63 (41), ⟨10.1002/anie.202407888⟩ Journal articles hal-04788264v1
	Do Not Waste Time─Ensure Success in Your Cross-Linking Mass Spectrometry Experiments before You Begin Lucienne Nouchikian , David Fernandez-Martinez , Pierre-Yves Renard , Cyrille Sabot , Guillaume Duménil Analytical Chemistry, 2024, 96 (6), pp.2506 - 2513. ⟨10.1021/acs.analchem.3c04682⟩ Journal articles hal-04727678v1
	Revisiting the Chemistry and Photophysics of 3‐( N ‐Methylpyridinium‐4‐yl)Coumarins for Designing "Covalent‐Assembly" and "Molecular Disassembly" Fluorescent Probes Vincent Gaumerd , Kévin Renault , Pierre‐yves Renard , Anthony Romieu ChemPhotoChem, 2024, 8 (5), ⟨10.1002/cptc.202300324⟩ Journal articles hal-04574555v1
	Biological response and cell death signaling pathways modulated by tetrahydroisoquinoline-based aldoximes in human cells Antonio Zandona , Josip Madunić , Katarina Miš , Nikola Maraković , Pierre Dubois-Geoffroy Toxicology, 2023, 494, pp.153588. ⟨10.1016/j.tox.2023.153588⟩ Journal articles hal-04635900v1
	Design and Synthesis of Chemiluminescent Cassettes Based on Energy Transfer Steven Vertueux , Alexandre Haefele , Kathleen Solmont , Philippe Durand , Pierre‐yves Renard European Journal of Organic Chemistry, 2023, 26 (13), pp.e202201401. ⟨10.1002/ejoc.202201401⟩ Journal articles hal-04059368v1
	Metalloenzyme‐Mediated Thiol‐Yne Addition Towards Photoisomerizable Fluorescent Dyes Alexis Lossouarn , Chloé Puteaux , Laetitia Bailly , Vincent Tognetti , Laurent Joubert Chemistry - A European Journal, inPress, ⟨10.1002/chem.202202180⟩ Journal articles hal-03808088v1
	A New Class of Bi- and Trifunctional Sugar Oximes as Antidotes against Organophosphorus Poisoning Ophélie da Silva , Nicolas Probst , Christophe Landry , Anne-Sophie Hanak , Pierre Warnault Journal of Medicinal Chemistry, 2022, 65 (6), pp.4649-4666. ⟨10.1021/acs.jmedchem.1c01748⟩ Journal articles hal-03706969v1
	Soft and effective detoxification of a VX simulant in a 3D printed basic flow reactor Sergui Mansour , Antonin Delaune , Maxime Manneveau , Baptiste Picard , Amélie Claudel Green Chemistry, 2021, pp.7522-7527. ⟨10.1039/D1GC01961A⟩ Journal articles hal-03353830v1
	Flow neutralisation of sulfur-containing chemical warfare agents with Oxone: packed-bed vs. aqueous solution Antonin Delaune , Sergui Mansour , Baptiste Picard , Philippe Carrasqueira , Isabelle Chataigner Green Chemistry, 2021, 23 (8), pp.2925-2930. ⟨10.1039/D1GC00449B⟩ Journal articles hal-03353823v1
	3-Benzoylquinoxalinone as a photoaffinity labelling derivative with fluorogenic properties allowing reaction monitoring under “no-wash” conditions Madeleine Cauwel , Clément Guillou , Kévin Renault , Damien Schapman , Magalie Bénard Chemical Communications, 2021, 57 (32), pp.3893-3896. ⟨10.1039/D1CC01072G⟩ Journal articles hal-03419993v1
	Tailored Bioorthogonal and Bioconjugate Chemistry: A Source of Inspiration for Developing Kinetic Target-Guided Synthesis Strategies Alexis Lossouarn , Pierre-Yves Renard , Cyrille Sabot Bioconjugate Chemistry, 2021, 32 (1), pp.63-72. ⟨10.1021/acs.bioconjchem.0c00568⟩ Journal articles hal-03419994v1
	One-Pot Synthesis of Diazirines and 15N2-Diazirines from Ketones, Aldehydes and Derivatives: Development and Mechanistic Insight Quentin Ibert , Madeleine Cauwel , Thomas Glachet , Tony Tite , Patricia Le Nahenec-Martel Advanced Synthesis and Catalysis, 2021, 363 (18), pp.4390-4398. ⟨10.1002/adsc.202100679⟩ Journal articles hal-03331796v1
	Discovery of a Potent Dual Inhibitor of Acetylcholinesterase and Butyrylcholinesterase with Antioxidant Activity that Alleviates Alzheimer-like Pathology in Old APP/PS1 Mice Elisabet Viayna , Nicolas Coquelle , Monika Cieslikiewicz-Bouet , Pedro Cisternas , Carolina Oliva Journal of Medicinal Chemistry, 2020, ⟨10.1021/acs.jmedchem.0c01775⟩ Journal articles hal-03094189v1
	Maleimide-based metal-free ligation with dienes: a comparative study Alexis Lossouarn , Kévin Renault , Laëtitia Bailly , Axel Frisby , Patricia Le Nahenec-Martel Organic & Biomolecular Chemistry, 2020, 18 (20), pp.3874-3887. ⟨10.1039/D0OB00403K⟩ Journal articles hal-03010566v1
	Fluorophore-assisted click chemistry through copper(I) complexation Victor Flon , Magalie Bénard , Damien Schapman , Ludovic Galas , Pierre-Yves Renard Biomolecules, 2020, Novel Approaches in Biomolecule Labeling, 10 (4), pp.619. ⟨10.3390/biom10040619⟩ Journal articles hal-03034414v1
	Functional characterization of multifunctional ligands targeting acetylcholinesterase and alpha 7 nicotinic acetylcholine receptor Monika Cieslikiewicz-Bouet , Marina Naldi , Manuela Bartolini , Belén Pérez , Denis Servent Biochemical Pharmacology, 2020, 177, ⟨10.1016/j.bcp.2020.114010⟩ Journal articles hal-02560260v1
	Chromogranin A preferential interaction with Golgi phosphatidic acid induces membrane deformation and contributes to secretory granule biogenesis Ophélie Carmon , Fanny Laguerre , Lina Riachy , Charlène Delestre-Delacour , Qili Wang FASEB Journal, 2020, 34 (5), pp.6769-6790. ⟨10.1096/fj.202000074R⟩ Journal articles hal-02525074v1
	Dearomatization of a 3-Hydroxypyridine through an unexpected Oxidative Deformylation Process: an Entry to Aza-cyclohexadienones Afef Mabrouki , Patricia Le Nahenec-Martel , Abdelkader Kriaa , Ahmed Hedhli , Pierre-Yves Renard SYNLETT, 2020, 31 (15), pp.1497-1500. ⟨10.1055/s-0040-1706870⟩ Journal articles hal-03010593v1
	Pharmacokinetic Evaluation of Brain Penetrating Morpholine-3-hydroxy-2-pyridine Oxime as an Antidote for Nerve Agent Poisoning Tamara Zorbaz , Petra Mišetić , Nicolas Probst , Suzana Žunec , Antonio Zandona ACS Chemical Neuroscience, 2020, 11 (7), pp.1072-1084. ⟨10.1021/acschemneuro.0c00032⟩ Journal articles hal-02505607v1
	Mono- and Poly-unsaturated Phosphatidic Acid Regulate Distinct Steps of Regulated Exocytosis in Neuroendocrine Cells Émeline Tanguy , Pierre Costé de Bagneaux , Nawal Kassas , Mohamed-Raafet Ammar , Qili Wang Cell Reports, 2020, 32 (7), pp.108026. ⟨10.1016/j.celrep.2020.108026⟩ Journal articles hal-02922310v1
	Investigation of tetrazine reactivity towards C-nucleophiles: pyrazolone-based modification of biomolecules Kévin Renault , Clément Guillou , Pierre-Yves Renard , Cyrille Sabot Organic & Biomolecular Chemistry, 2019, 17 (2), pp.388-396. ⟨10.1039/C8OB02108B⟩ Journal articles hal-02329641v1
	Regioselective Solid-Phase Synthesis of Peptide Analogues Containing 3,4- or 3,5-Disubstituted Isoxazole as s-cis or s-trans Peptide Bond Mimics Pierrick Bruyat , Ludovic Jean , Pierre-Yves Renard European Journal of Organic Chemistry, 2019, 2019 (20), pp.3134-3141. ⟨10.1002/ejoc.201900378⟩ Journal articles hal-02319741v1
	Real-time molecular optical micro-imaging of EGFR mutations using a fluorescent erlotinib based tracer Maxime Patout , Florian Guisier , Xavier Brune , Pierre Bohn , Anthony Romieu BMC Pulmonary Medicine, 2019, 19, pp.3. ⟨10.1186/s12890-018-0760-z⟩ Journal articles hal-02353026v1
	Reinvestigation of the synthesis of “covalent-assembly” type probes for fluoride ion detection. Identification of novel 7-(diethylamino)coumarins with aggregation-induced emission properties Valentin Quesneau , Benoît Roubinet , Pierre-Yves Renard , Anthony Romieu Tetrahedron Letters, 2019, 60 (48), pp.151279. ⟨10.1016/j.tetlet.2019.151279⟩ Journal articles hal-02320124v1
	Design, biological evaluation and X-ray crystallography of nanomolar multifunctional ligands targeting simultaneously acetylcholinesterase and glycogen synthase kinase-3 Killian Oukoloff , Nicolas Coquelle , Manuela Bartolini , Marina Naldi , Rémy Le Guével European Journal of Medicinal Chemistry, 2019, 168, pp.58-77. ⟨10.1016/j.ejmech.2018.12.063⟩ Journal articles hal-02055769v1
	Toward an Innovative Treatment of Alzheimer’s Disease: Design of MTDLs Targeting Acetylcholinesterase and α-7 Nicotinic Receptors Mégane Pons , Sylvie Chalon , Ludovic Jean , Pierre-Yves Renard , Frederic Buron Proceedings, 2019, 22 (1), pp.88. ⟨10.3390/proceedings2019022088⟩ Journal articles hal-02352595v1
	Diverted Natural Lossen-type Rearrangement for Bioconjugation through in Situ Myrosinase-Triggered Isothiocyanate Synthesis Jean Wilfried Fredy , Giuliano Cutolo , Benjamin Poret , Reine Nehmé , Marie Hubert-Roux Bioconjugate Chemistry, 2019, 30 (5), pp.1385-1394. ⟨10.1021/acs.bioconjchem.9b00153⟩ Journal articles hal-02280045v1
	Detection of Biothiols with a Fast-Responsive and Water-Soluble Pyrazolone-Based Fluorogenic Probe Kévin Renault , Pierre-Yves Renard , Cyrille Sabot European Journal of Organic Chemistry, 2018, 2018 (46), pp.6494-6498. ⟨10.1002/ejoc.201801157⟩ Journal articles hal-02024529v1
	Combination delivery of two oxime-loaded lipid nanoparticles: Time-dependent additive action for prolonged rat brain protection T.N. Pashirova , Anissa Braïki , I.V. Zueva , K.A. Petrov , V.M. Babaev Journal of Controlled Release, 2018, 290, pp.102-111. ⟨10.1016/j.jconrel.2018.10.010⟩ Journal articles hal-02024524v1
	Bifunctional mannoside-glucosinolate glycoconjugates as enzymatically triggered isothiocyanates and FimH ligands G. Cutolo , F. Reise , M. Schuler , R. Nehmé , G. Despras Organic & Biomolecular Chemistry, 2018, 16 (26), pp.4900-4913. ⟨10.1039/C8OB01128A⟩ Journal articles hal-02024493v1
	Use of an Air-Stable Cu(I)-NHC Catalyst for the Synthesis of Peptidotriazoles Pierrick Bruyat , Arnaud Gautier , Ludovic Jean , Pierre-Yves Renard Journal of Organic Chemistry, 2018, 83 (21), pp.13515-13522. ⟨10.1021/acs.joc.8b01490⟩ Journal articles hal-01916360v1
	Structure-Based Optimization of Nonquaternary Reactivators of Acetylcholinesterase Inhibited by Organophosphorus Nerve Agents Gianluca Santoni , J. de Sousa , Eugenio de La Mora , J. Dias , Ludovic Jean Journal of Medicinal Chemistry, 2018, 61 (17), pp.7630-7639. ⟨10.1021/acs.jmedchem.8b00592⟩ Journal articles hal-02024531v1
	Potent 3‐Hydroxy‐2‐Pyridine Aldoxime Reactivators of Organophosphate‐Inhibited Cholinesterases with Predicted Blood–Brain Barrier Penetration Tamara Zorbaz , Anissa Braïki , Nikola Marakovic , Julien Renou , Eugenio de La Mora Chemistry - A European Journal, 2018, 24 (38), pp.9675-9691. ⟨10.1002/chem.201801394⟩ Journal articles hal-02024542v1
	Covalent Modification of Biomolecules through Maleimide-Based Labeling Strategies Kévin Renault , J.W. Fredy , Pierre-Yves Renard , Cyrille Sabot Bioconjugate Chemistry, 2018, 29 (8), pp.2497-2513. ⟨10.1021/acs.bioconjchem.8b00252⟩ Journal articles hal-02024527v1
	Increasing Polarity in Tacrine and Huprine Derivatives: Potent Anticholinesterase Agents for the Treatment of Myasthenia Gravis Carles Galdeano , Nicolas Coquelle , Monika Cieslikiewicz-Bouet , Manuela Bartolini , Belén Pérez Molecules, 2018, 23 (3), pp.634. ⟨10.3390/molecules23030634⟩ Journal articles hal-01807857v1
	A miniaturized peptidyl-prolyl isomerase enzyme assay Mirella Vivoli , Julien Renou , Arnaud Chevalier , Isobel H. Norville , Suraya Diaz Analytical Biochemistry, 2017, 536, pp.59-68. ⟨10.1016/j.ab.2017.08.004⟩ Journal articles hal-02046314v1
	Selective and sensitive near‐infrared fluorescent probe for acetylcholinesterase imaging [abstract] Pierre-Yves Renard , Ludovic Jean Journal of Neurochemistry, 2017, 142 (S2), pp.188-225. ⟨10.1111/jnc.13925⟩ Journal articles hal-02329887v1
	Regioselective synthesis of o-triazolyl-1,5-benzodiazepin-2-ones and o-isoxazolyl-1,5-benzodiazepin-2-ones via copper-catalyzed 1,3-dipolar cycloaddition reactions H. Mtiraoui , A. Nsira , M. Msaddek , Pierre-Yves Renard , Cyrille Sabot Comptes Rendus. Chimie, 2017, 20 (7), pp.747-757. ⟨10.1016/j.crci.2017.02.004⟩ Journal articles hal-02046301v1
	Controlling Plasma Stability of Hydroxamic Acids: A MedChem Toolbox Paul Hermant , Damien Bosc , Catherine Piveteau , Ronan Gealageas , Baovy Lam Journal of Medicinal Chemistry, 2017, 60 (21), pp.9067-9089. ⟨10.1021/acs.jmedchem.7b01444⟩ Journal articles hal-03054238v1
	An easy method for the determination of active concentrations of cholinesterase reactivators in blood samples: Application to the efficacy assessment of non quaternary reactivators compared to HI-6 and pralidoxime in VX-poisoned mice André-Guilhem Calas , José Dias , Catherine Rousseau , Mélanie Arboléas , Mélanie Touvrey-Loiodice Chemico-Biological Interactions, 2017, 267 (1), pp.11-16. ⟨10.1016/j.cbi.2016.03.009⟩ Journal articles hal-02046266v1
	Metal-free oxidative ring contraction of benzodiazepinones: an entry to quinoxalinones Hasan Mtiraoui , Kévin Renault , Morgane Sanselme , Moncef Msaddek , Pierre-Yves Renard Organic & Biomolecular Chemistry, 2017, 15 (14), pp.3060-3068. ⟨10.1039/C7OB00205J⟩ Journal articles hal-02329806v1
	On the Influence of the Protonation States of Active Site Residues on AChE Reactivation: A QM/MM Approach Thomas Driant , Florian Nachon , Cyril Ollivier , Pierre-Yves Renard , Etienne Derat ChemBioChem, 2017, 18 (7), pp.666-675. ⟨10.1002/cbic.201600646⟩ Journal articles hal-01644385v1
	Photophysical properties of quinoxalin-2(1H)-ones: Application in the preparation of an azide-based fluorogenic probe for the detection of hydrogen sulfide Kévin Renault , Pierre-Yves Renard , Cyrille Sabot New Journal of Chemistry, 2017, 41 (18), pp.10432-10437. ⟨10.1039/c7nj01893b⟩ Journal articles hal-02046306v1
	Azo-based Fluorogenic Probes for Biosensing and Bioimaging: Recent Advances and Upcoming Challenges Arnaud Chevalier , Pierre-Yves Renard , Anthony Romieu Chemistry - An Asian Journal, 2017, 12 (16), pp.2008-2028. ⟨10.1002/asia.201700682⟩ Journal articles hal-01562215v1
	Probing the cholinergic system to understand neurodegenerative diseases Pierre-Yves Renard , Ludovic Jean Future Medicinal Chemistry, 2017, 9 (2), pp.131-133. ⟨10.4155/fmc-2016-0213⟩ Journal articles hal-02046305v1
	Solution and solid-state fluorescence of 2-(2′-hydroxyphenyl)-1,5-benzodiazepin-2-one (HBD) borate complexes Hasan Mtiraoui , Rafik Gharbi , Moncef Msaddek , Yann Bretonnière , Chantal Andraud RSC Advances, 2016, 6 (89), pp.86352-86360. ⟨10.1039/C6RA19246G⟩ Journal articles hal-01526238v1
	1,5-Benzodiazepin-2-ones: Investigation of a Family of Photoluminescent Materials Hasan Mtiraoui , Rafik Gharbi , Moncef Msaddek , Yann Bretonnière , Chantal Andraud Journal of Organic Chemistry, 2016, 81 (11), pp.4720-4727. ⟨10.1021/acs.joc.6b00627⟩ Journal articles hal-01526233v1
	Readily functionalizable phosphonium-tagged fluorescent coumarins for enhanced detection of conjugates by mass spectrometry Antoine Lizzul-Jurse , Laëtitia Bailly , Marie Hubert-Roux , Carlos Afonso , Pierre-Yves Renard Organic & Biomolecular Chemistry, 2016, 14 (32), pp.7777-7791. ⟨10.1039/c6ob01080f⟩ Journal articles hal-02046223v1
	Synthesis and photophysical properties of iron-carbonyl complex–coumarin conjugates as potential bimodal IR–fluorescent probes Paulina C. Glowacka , Nicolas Maindron , G. Richard Stephenson , Anthony Romieu , Pierre-Yves Renard Tetrahedron Letters, 2016, 57 (45), pp.4991-4996. ⟨10.1016/j.tetlet.2016.09.091⟩ Journal articles hal-01428754v1
	Improved Access to Huprine Derivatives Functionalized at Position 9 Killian Oukoloff , Sovy Chao , Monika Cieslikiewicz-Bouet , Romain Mougeot , Ludovic Jean European Journal of Organic Chemistry, 2016, 2016 (7), pp.1337-1343. ⟨10.1002/ejoc.201501433⟩ Journal articles hal-02046230v1
	5-Alkoxyoxazole –A Versatile Building Block in (Bio)organic Synthesis Laurie-Anne Jouanno , Kévin Renault , Cyrille Sabot , Pierre-Yves Renard European Journal of Organic Chemistry, 2016, 2016 (20), pp.3264-3281. ⟨10.1002/ejoc.201600127⟩ Journal articles hal-02046218v1
	A selective and sensitive near-infrared fluorescent probe for acetylcholinesterase imaging Sovy Chao , Eric Krejci , Véronique Bernard , Jacqueline Leroy , Ludovic Jean Chemical Communications, 2016, 52 (77), pp.11599-11602. ⟨10.1039/c6cc05936h⟩ Journal articles hal-03013508v1
	Fluorogenic Behaviour of the Hetero-Diels–Alder Ligation of 5-Alkoxyoxazoles with Maleimides and their Applications Kévin Renault , Laurie-Anne Jouanno , Antoine Lizzul-Jurse , Pierre-Yves Renard , Cyrille Sabot Chemistry - A European Journal, 2016, 22 (51), pp.18522-18531. ⟨10.1002/chem.201603617⟩ Journal articles hal-02046236v1
	Synthesis and in vitro evaluation of donepezil-based reactivators and analogues for nerve agent-inhibited human acetylcholinesterase Julien Renou , José Dias , Guillaume Mercey , Tristan Verdelet , Catherine Rousseau RSC Advances, 2016, 6 (22), pp.17929-17940. ⟨10.1039/c5ra25477a⟩ Journal articles hal-02046237v1
	A FRET-based probe for fluorescence sensing of sulfide/sulfite analytes, using a novel long-wavelength water-soluble 7-hydroxycoumarin as reporter fluorophore Benoît Roubinet , Laëtitia Bailly , Emilie Petit , Pierre-Yves Renard , Anthony Romieu Tetrahedron Letters, 2015, 56 (8), pp.1015-1019. ⟨10.1016/j.tetlet.2015.01.042⟩ Journal articles hal-01150270v1
	Azobenzene-caged sulforhodamine dyes: A novel class of 'turn-on' reactive probes for hypoxic tumor cell imaging Arnaud Chevalier , Wen Piao , Kenjiro Hanaoka , Tetsuo Nagano , Pierre-Yves Renard Methods and Applications in Fluorescence, 2015, 3 (4), pp.044004. ⟨10.1088/2050-6120/3/4/044004⟩ Journal articles hal-02046143v1
	Fast-Responsive Nitroso-Based Turn-On Probe for Hydrogen Sulfide Kévin Renault , Cyrille Sabot , Pierre-Yves Renard European Journal of Organic Chemistry, 2015, 2015 (36), pp.7992-7996. ⟨10.1002/ejoc.201501140⟩ Journal articles hal-02046170v1
	New insights into the kinetic target-guided synthesis of protein ligands E. Oueis , Cyrille Sabot , Pierre-Yves Renard Chemical Communications, 2015, 51 (61), pp.12158-12169. ⟨10.1039/c5cc04183j⟩ Journal articles hal-02046164v1
	Synthetic Route to Rare Isoindolones Derivatives Killian Oukoloff , Frederic Buron , Sylvain Routier , Ludovic Jean , Pierre-Yves Renard European Journal of Organic Chemistry, 2015, 2015 (11), pp.2450-2456. ⟨10.1002/ejoc.201403649⟩ Journal articles hal-01150276v1
	A Synthetic Route to 3-(Heteroaryl)-7-hydroxycoumarins Designed for Biosensing Applications Benoît Roubinet , Arnaud Chevalier , Pierre-Yves Renard , Anthony Romieu European Journal of Organic Chemistry, 2015, 2015 (1), pp.166-182. ⟨10.1002/ejoc.201403215⟩ Journal articles hal-01150273v1
	Rapid Synthesis of Unsymmetrical Sulforhodamines Through Nucleophilic Amination of a Monobrominated Sulfoxanthene Dye Arnaud Chevalier , Kévin Renault , Frederic Boschetti , Pierre-Yves Renard , Anthony Romieu European Journal of Organic Chemistry, 2015, 2015 (1), pp.152-165. ⟨10.1002/ejoc.201403165⟩ Journal articles hal-01150274v1
	Rational Design of Latent Fluorophores from Water-Soluble Hydroxyphenyltriazine Dyes Suitable for Lipase Sensing Alicia Jacquemet , Sandra Rihn , Gilles Ulrich , Pierre-Yves Renard , Anthony Romieu European Journal of Organic Chemistry, 2015, 2015 (8), pp.1664-1669. ⟨10.1002/ejoc.201500047⟩ Journal articles hal-01150275v1
	PET and SPECT radiotracers for Alzheimer's disease Killian Oukoloff , Monika Cieslikiewicz-Bouet , Sovy Chao , Emilie da Costa Branquinho , C. Bouteiller Current Medicinal Chemistry, 2015, 22 (28), pp.3278-3304. ⟨10.2174/0929867322666150805094645⟩ Journal articles hal-02046165v1
	Multi-target directed ligands: Electrophysiological characterization of an anticholinesterase inhibitor coupled to an agonist of α7 nicotinic acetylcholine receptor Rómulo Aráoz , Monika Bouet , Manuela Bartolini , Nicolas Coquelle , Jacques-Philippe Colletier Biochemical Pharmacology, 2015, 97 (4), pp.621. ⟨10.1016/j.bcp.2015.08.006⟩ Journal articles hal-02329901v1
	New 3-(Heteroaryl)-2-iminocoumarin-based Borate Complexes: Synthesis, Photophysical Properties, and Rational Functionalization for Biosensing/Biolabeling Applications Benoît Roubinet , Cédrik Massif , Mathieu Moreau , F. Boschetti , Gilles Ulrich Chemistry - A European Journal, 2015, 21 (41), pp.14589-14601. ⟨10.1002/chem.201502126⟩ Journal articles hal-02046171v1
	Design, synthesis and biological evaluation of novel tetrahydroacridine pyridine- aldoxime and -amidoxime hybrids as efficient uncharged reactivators of nerve agent-inhibited human acetylcholinesterase Maria Kliachyna , Gianluca Santoni , Valentin Nussbaum , Julien Renou , Benoît Sanson European Journal of Medicinal Chemistry, 2014, 78, pp.455-467. ⟨10.1016/j.ejmech.2014.03.044⟩ Journal articles hal-01131268v1
	Synthesis of fluorinated agonist of sphingosine-1-phosphate receptor 1 Lucie Aliouane , Sovy Chao , Brizuela Leyre , Emmanuel Pfund , Cuvillier Olivier Bioorganic and Medicinal Chemistry, 2014, 22 (17), pp.4955-4960. ⟨10.1016/j.bmc.2014.06.038⟩ Journal articles hal-01063240v1
	Kondrat'eva ligation: Diels-Alder-based irreversible reaction for bioconjugation Laurie-Anne Jouanno , Arnaud Chevalier , Nawal Sekkat , Nicolas Perzo , Hélène Castel Journal of Organic Chemistry, 2014, 79 (21), pp.10353-10366. ⟨10.1021/jo501972m⟩ Journal articles hal-01144842v1
	New insights into the water-solubilization of thiol-sensitive fluorogenic probes based on long-wavelength 7-hydroxycoumarin scaffolds Benoît Roubinet , Pierre-Yves Renard , Anthony Romieu Dyes and Pigments, 2014, 110, pp.270-284. ⟨10.1016/j.dyepig.2014.02.004⟩ Journal articles hal-01150279v1
	Straightforward synthesis of bioconjugatable azo dyes. Part 2: Black Hole Quencher-2 (BHQ-2) and BlackBerry Quencher 650 (BBQ-650) scaffolds Arnaud Chevalier , Pierre-Yves Renard , Anthony Romieu Tetrahedron Letters, 2014, 50 (55), pp.6764-6768. ⟨10.1016/j.tetlet.2014.10.054⟩ Journal articles hal-01150282v1
	Straightforward Access to Water-Soluble Unsymmetrical Sulfoxanthene Dyes: Application to the Preparation of Far-Red Fluorescent Dyes with Large Stokes' Shifts Arnaud Chevalier , Pierre-Yves Renard , Anthony Romieu Chemistry - A European Journal, 2014, 20 (27), pp.8330-8337. ⟨10.1002/chem.201402306⟩ Journal articles hal-01150280v1
	Azo-Sulforhodamine Dyes: A Novel Class of Broad Spectrum Dark Quenchers Arnaud Chevalier , Pierre-Yves Renard , Anthony Romieu Organic Letters, 2014, 16 (15), pp.3946-3949. ⟨10.1021/ol501753b⟩ Journal articles hal-02335871v1
	Metal-Free Decarboxylative Hetero-Diels-Alder Synthesis of 3-Hydroxypyridines: A Rapid Access to N-Fused Bicyclic Hydroxypiperidine Scaffolds. Laurie-Anne Jouanno , Vincent Di Mascio , Vincent Tognetti , Laurent Joubert , Cyrille Sabot Journal of Organic Chemistry, 2014, 79 (3), pp.1303-1319. ⟨10.1021/jo402729a⟩ Journal articles hal-00996570v1
	Biochemical Characterization of a Caspase-3 Far-red Fluorescent Probe for Non-invasive Optical Imaging of Neuronal Apoptosis Valérie Jolivel , Sébastien Arthaud , Béatrice Botia , Christophe Portal , Bruno Delest Journal of Molecular Neuroscience, 2014, 54 (3), pp.451-462. ⟨10.1007/s12031-014-0325-4⟩ Journal articles hal-01196843v1
	Tryptoline-3-hydroxypyridinaldoxime conjugates as efficient reactivators of phosphylated human acetyl and butyrylcholinesterase Julien Renou , Melanie Loiodice , Melanie Arboleas , Rachid Baati , Ludovic Jean Chemical Communications, 2014, 50 (30), pp.3947-3950. ⟨10.1039/C4CC00561A⟩ Journal articles hal-01150284v1
	Straightforward synthesis of bioconjugatable azo dyes. Part 1: Black Hole Quencher-1 (BHQ-1) scaffold Arnaud Chevalier , Pierre-Yves Renard , Anthony Romieu Tetrahedron Letters, 2014, 55 (50), pp.6759-6763. ⟨10.1016/j.tetlet.2014.10.053⟩ Journal articles hal-01150281v1
	Reaction site-driven regioselective synthesis of AChE inhibitors Emilia Oueis , Gianluca Santoni , Cyril Ronco , Olga A. Syzgantseva , Vincent Tognetti Organic & Biomolecular Chemistry, 2014, 12 (1), pp.156-161. ⟨10.1039/C3OB42109K⟩ Journal articles hal-02335933v1
	First enzymatic hydrolysis/thio-Michael addition cascade route to synthesis of AChE inhibitors. Emilia Oueis , Florian Nachon , Cyrille Sabot , Pierre-Yves Renard Chemical Communications, 2014, 50 (16), pp.2043-2045. ⟨10.1039/c3cc48871c⟩ Journal articles hal-00996567v1
	Synthesis, biological evaluation, and in vivo imaging of the first camptothecin-fluorescein conjugate. Arnaud Chevalier , Martine Dubois , Vadim Le Joncour , Sébastien Dautrey , Céline Lecointre Bioconjugate Chemistry, 2013, 24 (7), pp.1119-1133. ⟨10.1021/bc3005304⟩ Journal articles hal-00996547v1
	Strategies for the selection of catalytic antibodies against organophosphorus nerve agents. Ivan Smirnov , Alexey Belogurov , Alain Friboulet , Patrick Masson , Alexander Gabibov Chemico-Biological Interactions, 2013, 203 (1), pp.196-201. ⟨10.1016/j.cbi.2012.10.011⟩ Journal articles hal-00996534v1
	Thermally controlled decarboxylative [4 + 2] cycloaddition between alkoxyoxazoles and acrylic acid: expedient access to 3-hydroxypyridines. Laurie-Anne Jouanno , Vincent Tognetti , Laurent Joubert , Cyrille Sabot , Pierre-Yves Renard Organic Letters, 2013, 15 (10), pp.2530-2533. ⟨10.1021/ol4010195⟩ Journal articles hal-00996416v1
	Radiosynthesis and in vivo evaluation of fluorinated huprine derivates as PET radiotracers of acetylcholinesterase Emilie da Costa Branquinho , Guillaume Becker , Cédric Bouteiller , Ludovic Jean , Pierre-Yves Renard Nuclear Medicine and Biology, 2013, 40 (4), pp.554-560. ⟨10.1016/j.nucmedbio.2013.02.004⟩ Journal articles hal-00847401v1
	The first "ready-to-use" benzene-based heterotrifunctional cross-linker for multiple bioconjugation. Guillaume Viault , Sébastien Dautrey , Nicolas Maindron , Julie Hardouin , Pierre-Yves Renard Organic & Biomolecular Chemistry, 2013, 11 (16), pp.2693-2705. ⟨10.1039/c3ob40086g⟩ Journal articles hal-00996541v1
	Syntheses and in vitro evaluations of uncharged reactivators for human acetylcholinesterase inhibited by organophosphorus nerve agents. Julien Renou , Guillaume Mercey , Tristan Verdelet , Emilia Păunescu , Emilie Gillon Chemico-Biological Interactions, 2013, 203 (1), pp.81-84. ⟨10.1016/j.cbi.2012.09.023⟩ Journal articles hal-00996535v1
	The first comparative study of the ability of different hydrophilic groups to water-solubilize fluorescent BODIPY dyes Anthony Romieu , Cédrik Massif , Sandra Rihn , Gilles Ulrich , Raymond Ziessel New Journal of Chemistry, 2013, 37 (4), pp.1016-1027. ⟨10.1039/C3NJ41093E⟩ Journal articles hal-01015523v1
	Bioconjugatable azo-based dark-quencher dyes: synthesis and application to protease-activatable far-red fluorescent probes. Arnaud Chevalier , Cédrik Massif , Pierre-Yves Renard , Anthony Romieu Chemistry - A European Journal, 2013, 19 (5), pp.1686-1699. ⟨10.1002/chem.201203427⟩ Journal articles hal-00996530v1
	The first latent green fluorophores for the detection of azoreductase activity in bacterial cultures. Arnaud Chevalier , Claire Mercier , Laura Saurel , Sylvain Orenga , Pierre-Yves Renard Chemical Communications, 2013, 49 (78), pp.8815-8817. ⟨10.1039/c3cc44798g⟩ Journal articles hal-00996553v1
	Crystal structures of human cholinesterases in complex with huprine W and tacrine: elements of specificity for anti-Alzheimer's drugs targeting acetyl- and butyryl-cholinesterase. Florian Nachon , Eugénie Carletti , Cyril Ronco , Marie Trovaslet , Yvain Nicolet Biochemical Journal, 2013, 453 (3), pp.393-399. ⟨10.1042/BJ20130013⟩ Journal articles hal-00996550v1
	Universal dark quencher based on "clicked" spectrally distinct azo dyes. Arnaud Chevalier , Julie Hardouin , Pierre-Yves Renard , Anthony Romieu Organic Letters, 2013, 15 (23), pp.6082-6085. ⟨10.1021/ol402972y⟩ Journal articles hal-00996556v1
	A novel sulfonated prosthetic group for [18F]-radiolabelling and imparting water solubility of biomolecules and cyanine fluorophores. Thomas Priem , Cédric Bouteiller , Davide Camporese , Xavier Brune , Julie Hardouin Organic & Biomolecular Chemistry, 2013, 11 (3), pp.469-479. ⟨10.1039/c2ob26659h⟩ Journal articles hal-00996532v1
	Huprine derivatives as sub-nanomolar human acetylcholinesterase inhibitors: from rational design to validation by X-ray crystallography. Cyril Ronco , Eugénie Carletti , Jacques-Philippe Colletier , Martin Weik , Florian Nachon ChemMedChem, 2012, 7 (3), pp.400-405. ⟨10.1002/cmdc.201100438⟩ Journal articles hal-00996475v1
	Human butyrylcholinesterase produced in insect cells: huprine-based affinity purification and crystal structure. Xavier Brazzolotto , Marielle Wandhammer , Cyril Ronco , Marie Trovaslet , Ludovic Jean FEBS Journal, 2012, 279 (16), pp.2905-2916. ⟨10.1111/j.1742-4658.2012.08672.x⟩ Journal articles hal-00996490v1
	New insights into the water-solubilisation of fluorophores by post-synthetic "click" and Sonogashira reactions Cédrik Massif , Sébastien Dautrey , Alexandre Haefele , Raymond Ziessel , Pierre-Yves Renard Organic & Biomolecular Chemistry, 2012, 10 (22), pp.4330-4336. ⟨10.1039/c2ob25428j⟩ Journal articles hal-00996469v1
	Synthesis of polysubstituted 3-hydroxypyridines via the revisited hetero-Diels-Alder reaction of 5-alkoxyoxazoles with dienophiles. Cyrille Sabot , Emilia Oueis , Xavier Brune , Pierre-Yves Renard Chemical Communications, 2012, 48 (5), pp.768-770. ⟨10.1039/c1cc16562c⟩ Journal articles hal-00996467v1
	Screening of new huprines--inhibitors of acetylcholinesterases by electrospray ionization ion trap mass spectrometry Anna Ziemianin , Cyril Ronco , Romain Dolé , Ludovic Jean , Pierre-Yves Renard Journal of Pharmaceutical and Biomedical Analysis, 2012, 70, pp.1-5. ⟨10.1016/j.jpba.2012.01.038⟩ Journal articles hal-00996397v1
	Expeditious microwave-assisted synthesis of 5-alkoxyoxazoles from α-triflyloxy esters and nitriles. Laurie-Anne Jouanno , Cyrille Sabot , Pierre-Yves Renard Journal of Organic Chemistry, 2012, 77 (19), pp.8549-8555. ⟨10.1021/jo301527t⟩ Journal articles hal-00996502v1
	Reactivators of acetylcholinesterase inhibited by organophosphorus nerve agents Guillaume Mercey , Tristan Verdelet , Julien Renou , Maria Kliachyna , Rachid Baati Accounts of Chemical Research, 2012, 45 (5), pp.756-766. ⟨10.1021/ar2002864⟩ Journal articles hal-01015972v1
	Synthesis and reactivity of a bis-sultone cross-linker for peptide conjugation and [18F]-radiolabelling via unusual "double click" approach. Thomas Priem , Cédric Bouteiller , David Camporese , Anthony Romieu , Pierre-Yves Renard Organic & Biomolecular Chemistry, 2012, 10 (5), pp.1068-1078. ⟨10.1039/c1ob06600e⟩ Journal articles hal-00996479v1
	Water-soluble red-emitting distyryl-borondipyrromethene (BODIPY) dyes for biolabeling Song-Lin Niu , Cédrik Massif , Gilles Ulrich , Pierre-Yves Renard , Anthony Romieu Chemistry - A European Journal, 2012, 18 (23), pp.7229-7242. ⟨10.1002/chem.201103613⟩ Journal articles hal-00996473v1
	Phenyltetrahydroisoquinoline-pyridinaldoxime conjugates as efficient uncharged reactivators for the dephosphylation of inhibited human acetylcholinesterase. Guillaume Mercey , Julien Renou , Tristan Verdelet , Maria Kliachyna , Rachid Baati Journal of Medicinal Chemistry, 2012, 55 (23), pp.10791-10795. ⟨10.1021/jm3015519⟩ Journal articles hal-00996512v1
	Water-solubilisation and bio-conjugation of a red-emitting BODIPY marker Song Lin Niu , Cédrik Massif , Gilles Ulrich , Raymond Ziessel , Pierre-Yves Renard Organic & Biomolecular Chemistry, 2011, 9 (1), pp.66-69. ⟨10.1039/c0ob00693a⟩ Journal articles hal-00991914v1
	Straightforward and efficient synthesis of 3-benzyloxy-4-bromopicolinate ester and 3-benzyloxy-5-bromopicolinate ester, common building blocks for pharmaceuticals and agrochemicals Tristan Verdelet , Guillaume Mercey , Nobi Correa , Ludovic Jean , Pierre-Yves Renard Tetrahedron, 2011, 67 (45), pp.8757-8762. ⟨10.1016/j.tet.2011.09.024⟩ Journal articles hal-01017528v1
	Design, synthesis and evaluation of new alpha-nucleophiles for the hydrolysis of organophosphorus nerve agents: application to the reactivation of phosphorylated acetylcholinesterase Géraldine Saint-André , Maria Kliachyna , Sanjeevarao Kodepelly , Ludivine Louise-Leriche , Emilie Gillon Tetrahedron, 2011, 67 (34), pp.6352-6361. ⟨10.1016/j.tet.2011.05.130⟩ Journal articles hal-01017442v1
	The first metal-free water-soluble cryptophane-111. Ténin Traoré , Guillaume Clavé , Léa Delacour , Naoko Kotera , Pierre-Yves Renard Chemical Communications, 2011, 47 (34), pp.9702-9704. ⟨10.1039/c1cc13378k⟩ Journal articles hal-00991921v1
	Optimized strategies to synthesize β-cyclodextrin-oxime conjugates as a new generation of organophosphate scavengers. Romain Le Provost , Timo Wille , Ludivine Louise , Nicolas Masurier , Susanne Müller Organic & Biomolecular Chemistry, 2011, 9 (8), pp.3026-3032. ⟨10.1039/c0ob00931h⟩ Journal articles hal-00991907v1
	First efficient uncharged reactivators for the dephosphylation of poisoned human acetylcholinesterase. Guillaume Mercey , Tristan Verdelet , Géraldine Saint-André , Emilie Gillon , Alain Wagner Chemical Communications, 2011, 47 (18), pp.5295-5297. ⟨10.1039/c1cc10787a⟩ Journal articles hal-00991912v1
	N-Fmoc-α-sulfo-β-alanine: a versatile building block for the water solubilisation of chromophores and fluorophores by solid-phase strategy. Anthony Romieu , Thomas Bruckdorfer , Guillaume Clavé , Virgile Grandclaude , Cédrik Massif Organic & Biomolecular Chemistry, 2011, 9 (15), pp.5337-5342. ⟨10.1039/c1ob05730h⟩ Journal articles hal-00991917v1
	Synthesis and luminescence properties of new red-shifted absorption lanthanide(III) chelates suitable for peptide and protein labelling. Nicolas Maindron , Séverine Poupart , Maxime Hamon , Jean-Baptiste Langlois , Nelly Plé Organic & Biomolecular Chemistry, 2011, 9 (7), pp.2357-2370. ⟨10.1039/c0ob00832j⟩ Journal articles hal-00991910v1
	Palladium-Catalyzed Preparation of N-Alkylated Tacrine and Huprine Compounds Cyril Ronco , Ludovic Jean , Hakim Outaabout , Pierre-Yves Renard European Journal of Organic Chemistry, 2011, 2011 (2), pp.302-310. ⟨10.1002/ejoc.201001158⟩ Journal articles hal-01017284v1
	Synthesis of difluoromethylphosphonamidates by direct addition of amine Lucie Aliouane , Baptiste Rigaud , Emmanuel Pfund , Ludovic Jean , Pierre-Yves Renard Tetrahedron Letters, 2011, 52 (28), pp.3681-3685. ⟨10.1016/j.tetlet.2011.05.034⟩ Journal articles hal-01017309v1
	A versatile access to new halogenated 7-azidocoumarins for photoaffinity labeling: Synthesis and photophysical properties Emilia Paunescu , Ludivine Louise , Ludovic Jean , Anthony Romieu , Pierre-Yves Renard Dyes and Pigments, 2011, 91 (3), pp.427-434. ⟨10.1016/j.dyepig.2011.05.008⟩ Journal articles hal-01017388v1
	New huprine derivatives functionalized at position 9 as highly potent acetylcholinesterase inhibitors. Cyril Ronco , Richard Foucault , Emilie Gillon , Pierre Bohn , Florian Nachon ChemMedChem, 2011, 6 (5), pp.876-888. ⟨10.1002/cmdc.201000523⟩ Journal articles hal-00991920v1
	A novel and unusually long-lived chemiluminophore based on the 7-hydroxycoumarin scaffold. Jan Kočí , Virgile Grandclaude , Marc Massonneau , Jean-Alexandre Richard , Anthony Romieu Chemical Communications, 2011, 47 (23), pp.6713-6715. ⟨10.1039/c1cc11919b⟩ Journal articles hal-00991904v1
	In Vitro and Ex Vivo Evaluation of Smart Infra-Red Fluorescent Caspase-3 Probes for Molecular Imaging of Cardiovascular Apoptosis Manuelle Debunne , Christophe Portal , Bruno Delest , Ebba Brakenhielm , Françoise Lallemand International Journal of Molecular Imaging, 2011, 2011, pp.413290. ⟨10.1155/2011/413290⟩ Journal articles inserm-02296580v1
	A comparative study of the self-immolation of para-aminobenzylalcohol and hemithioaminal-based linkers in the context of protease-sensitive fluorogenic probes. Yves Meyer , Jean-Alexandre Richard , Bruno Delest , Pauline Noack , Pierre-Yves Renard Organic & Biomolecular Chemistry, 2010, 8 (8), pp.1777-1780. ⟨10.1039/b926316k⟩ Journal articles hal-00991894v1
	Facile and rapid access to linear and truncated microcystin analogues for the implementation of immunoassays. G. Clavé , C. Ronco , H. Boutal , N. Kreich , H. Volland Organic & Biomolecular Chemistry, 2010, 8 (3), pp.676-690. ⟨10.1039/b920193a⟩ Journal articles hal-00991885v1
	Water solubilization of xanthene dyes by post-synthetic sulfonation in organic media Anthony Romieu , Delphine Tavernier-Lohr , S Pellet-Rostaing , Marc Lemaire , Pierre-Yves Renard Tetrahedron Letters, 2010, 51 (25), pp.3304-3308. ⟨10.1016/j.tetlet.2010.04.080⟩ Journal articles hal-01018665v1
	Improved synthetic pathway for the derivatization of huprine scaffold Cyril Ronco , Ludovic Jean , Pierre-Yves Renard Tetrahedron, 2010, 66 (37), pp.7399-7404. ⟨10.1016/j.tet.2010.07.021⟩ Journal articles hal-01019278v1
	A HTS assay for the detection of organophosphorus nerve agent scavengers. Ludivine Louise-Leriche , Emilia Paunescu , Géraldine Saint-André , Rachid Baati , Anthony Romieu Chemistry - A European Journal, 2010, 16 (11), pp.3510-3523. ⟨10.1002/chem.200902986⟩ Journal articles hal-00991892v1
	A universal and ready-to-use heterotrifunctional cross-linking reagent for facile synthetic access to sophisticated bioconjugates. Guillaume Clavé , Hervé Volland , Mélanie Flaender , Didier Gasparutto , Anthony Romieu Organic & Biomolecular Chemistry, 2010, 8 (19), pp.4329-4345. ⟨10.1039/c0ob00133c⟩ Journal articles hal-00991898v1
	Synthesis and structure–activity relationship of Huprine derivatives as human acetylcholinesterase inhibitors Cyril Ronco , Geoffroy Sorin , Florian Nachon , Richard Foucault , Ludovic Jean Bioorganic and Medicinal Chemistry Letters, 2009, 17 (13), pp.4523-4536. ⟨10.1016/j.bmc.2009.05.005⟩ Journal articles hal-03808202v1
	Additions and Corrections Pierre-Yves Renard Organic & Biomolecular Chemistry, 2009, 7 (24), pp.5271. ⟨10.1039/b922697b⟩ Journal articles hal-03808190v1
	Self-cleavable chemiluminescent probes suitable for protease sensing Jean-Alexandre Richard , Ludovic Jean , Caroline Schenkels , Marc Massonneau , Anthony Romieu Organic & Biomolecular Chemistry, 2009, 7 (14), pp.2941. ⟨10.1039/b905725k⟩ Journal articles hal-03808199v1
	Aryldithioethyloxycarbonyl (Ardec): A New Family of Amine Protecting Groups Removable under Mild Reducing Conditions and Their Applications to Peptide Synthesis Milaine Lapeyre , Jérôme Leprince , Marc Massonneau , Hassan Oulyadi , Pierre-Yves Renard Chemistry - A European Journal, 2006, 12 (13), pp.3655-3671. ⟨10.1002/chem.200501538⟩ Journal articles hal-01962803v1
	Aryldithioethyloxycarbonyl(Ardec) : a new family of aminoe protecting groups removable under mild reducing conditions and their applications to peptide synthesis. M. Lapeyre , Jérôme Leprince , M. Massonneau , Hassan Oulyadi , Pierre-Yves Renard Chemistry - A European Journal, 2006, 12, pp.3655-3671 Journal articles hal-00023718v1
	Lewis Acid Catalyzed Room-Temperature Michaelis–Arbuzov Rearrangement Pierre-Yves Renard , Philippe Vayron , Eric Leclerc , Alain Valleix , Charles Mioskowski Angewandte Chemie International Edition, 2003, 42 (21), pp.2389-2392. ⟨10.1002/anie.200250270⟩ Journal articles hal-02345149v1
	Stereoselective access to polyfunctionalized decalins Cyrille Poirel , P.Y. Renard , J.Y. Lallemand Tetrahedron Letters, 1994, 35 (35), pp.6485-6488 Journal articles hal-02710197v1

	Multi-target drug Ligands design and synthesis for Alzheimer disease backed by X-ray crystal analyses Pierre-Yves Renard Annual Conference of AnalytiX (7, 2019), Nov 2019, Berlin, Germany Conference papers hal-02404227v1
	Sondes pro-fluorescentes et chémiluminescentes pour la détection d'analyses d'intérêt biologique Pierre-Yves Renard Séminaire national, Institut Brestois Santé Agro Matière (IBSAM), May 2019, Brest, France Conference papers hal-02404291v1
	Overview of 3-hydroxy-pyridindaldoxime based reactivators Pierre-Yves Renard International workshop on nerve agents, North Atlantic Treaty Organisation (NATO), Nov 2018, Paris, France Conference papers hal-02403935v1
	Méthode de criblage : identification de catalyseurs de la réaction de Diels-Alder Cyrille Sabot , Laura Nogueira de Faria Cardoso , Pierre-Yves Renard , Wadih Ghattas , Jean-Pierre Mahy Journée scientifique du LabEx Chimie des Architectures Moléculaires Multifonctionnelles et des Matériaux (CHARMMMAT, 6, 2018)), Jun 2018, Cachan, France Conference papers hal-02372510v1
	Chimiluminescence in vivo Pierre-Yves Renard Rencontre ChiMi. Fluorescence : de la paillasse à l'utilisation clinique, Jan 2018, Dijon, France Conference papers hal-02395824v1
	Réactions de ligation fluorogéniques Pierre-Yves Renard Journées scientifiques de chémobiologie, Nov 2018, Lille, France Conference papers hal-02389306v1
	Sondes fluorogéniques pour la détection d'activités enzymatiques et d'analytes d'intérêt biologiques Pierre-Yves Renard Séminaire national, Institut des biomolécules Max Mousseron (IBMM, UMR 5247), Oct 2018, Montpellier, France Conference papers hal-02393849v1
	Méthode de criblage : identification de catalyseurs de la réaction de Diels-Alder Cyrille Sabot , Laura Nogueira de Faria Cardoso , Pierre-Yves Renard , Wadih Ghattas , Jean-Pierre Mahy Journée scientifique du LabEx Chimie des Architectures Moléculaires Multifonctionnelles et des Matériaux (CHARMMMAT, 6, 2018)), Jun 2018, Cachan, France Conference papers hal-03098307v1
	Pro-fluorescent and chemiluminescent probes for enzymatic activities detection Pierre-Yves Renard Séminaire national, Laboratoire des biomolécules (LBM, UMR 7203), May 2018, Paris, France Conference papers hal-02393089v1
	Fluorogenic Behaviour of the Hetero-Diels-Alder Ligation of 5-Alkoxyoxazoles with Maleimides and their Applications Pierre-Yves Renard International Caparica Conference on Chromogenic and Emissive Materials (3, 2018), Jun 2018, Lisbonne, Portugal Conference papers hal-02388673v1
	Novel centrally active antidote for intoxication by sarin and VX nerve agents T. Zorbaz , M. Katalinic , A. Zandona , Anissa Braïki , Ludovic Jean Congress of the Federation-of-European-Biochemical-Societies (FEBS) on From Molecules to Cells and Back (42, 2017), Sep 2017, Jérusalem, Israel. pp.242, ⟨10.1111/febs.14174⟩ Conference papers hal-02024992v1
	Toward an innovative treatment of Alzheimer's disease: Synthesis and evaluation of multi-target directed ligands (MTDLs) targeting acetylcholinesterase (AChE) and alpha7 nicotinic acetylchloline receptors (alpha7 nAChRs) Monika Cieslikiewicz-Bouet , Sovy Chao , Ludovic Jean , R. Araoz , D. Servent International Symposium on Cholinergic Mechanisms (ISCM, 15, 2016), Oct 2016, Marseille, France. pp.209-210 Conference papers hal-02024978v1
	Pro-fluorescent and chemiluminescent probes for enzymatic activities detection Pierre-Yves Renard Séminaire national, Institut de chimie de Nice (ICN, UMR 7272), Mar 2016, Nice, France Conference papers hal-02393073v1
	Water soluble unsymmetrical sulfoxanthene dyes - access to a novel class of broad spectrum dark quenchers Pierre-Yves Renard International Caparica Conference on Chromogenic and Emissive Materials (2, 2016), Sep 2016, Lisbonne, Portugal Conference papers hal-02388670v1
	L'acétylcholinestérase Pierre-Yves Renard Séminaire industriel, Servier, Mar 2016, Croissy-sur-Seine, France Conference papers hal-02391648v1
	Exemples d'utilisation de sondes fluorescentes pour détecter l'évolution et les impacts de traitements antitumoraux Pierre-Yves Renard Journée de présentation et d´échanges Chimie, Biologie et Cancer dans l´inter-région Nord-Ouest, Apr 2016, Amiens, France Conference papers hal-02395831v1
	New oximes for OP poisoned cholinesterases reactivation Pierre-Yves Renard International workshop on chemical warfare agents: toxicity, emergency response and medical countermeasures, Sep 2016, Paris, France Conference papers hal-02388800v1
	The effects of organophosphorus compounds and novel antidotes on human neuronal cells T. Zorbaz , M. Katalinic , I. Pavicic , Anissa Braïki , J. Renou International Symposium on Cholinergic Mechanisms (ISCM, 15, 2016), Oct 2016, Marseille, France. pp.224-225 Conference papers hal-02024991v1
	Heterotrifunctionnal linkers for bioconjugate reactions Pierre-Yves Renard The Missing link biologically driven ligation of carbohydrates and proteins, Jun 2016, Kiel, Germany Conference papers hal-02389804v1
	Hupresin, a new affinity resin to purify butyrylcholinesterase E. David , C. Ronco , Ludovic Jean , X. Brazzolotto , F. Nachon International Symposium on Cholinergic Mechanisms (ISCM, 15, 2017), Oct 2016, Marseille, France. pp.210, ⟨10.1111/jnc.13925⟩ Conference papers hal-02024979v1
	Selective and sensitive near-infrared fluorescent probe for acetylcholinesterase imaging Sovy Chao , Ludovic Jean , E. Krejci , Pierre-Yves Renard International Symposium on Cholinergic Mechanisms (ISCM, 15, 2017), Oct 2016, Marseille, France. pp.209, ⟨10.1111/jnc.13925⟩ Conference papers hal-02024977v1
	L'acétylcholinestérase : une enzyme modèle pour le chimiste bio-organicien Pierre-Yves Renard Séminaire national, Institut de chimie moléculaire de l'Université de Bourgogne (ICMUB, UMR 6302), Apr 2015, Dijon, France Conference papers hal-02391659v1
	Dynamic mapping of acetylcholinesterase for structural-dynamics based reactivator design G. Santoni , E. de La Mora , J.-P. Colletier , Ludovic Jean , Y. Xu 12th International Meeting on Cholinesterases, Sep 2015, Elche, Spain Conference papers hal-02024984v1
	Insights on two in situ click chemistry reactions for the synthesis of AChE inhibitors E. Oueis , Ronco C. , F. Nachon , Cyrille Sabot , Ludovic Jean International Meeting on Cholinesterases - Sixth International Conference on Paraoxonases (12, 2015), Sep 2015, Elche, Spain Conference papers hal-02379142v1
	Evaluation of three novel hydroxypicolinaldehyde oximes as efficient uncharged reactivators of VX-inhibited human acetylcholinesterase Z. Kovarik , M. Katalinic , Ludovic Jean , Pierre-Yves Renard , Renou J. FEBS-EMBO Anniversary Conference, Federation of European Biochemical Societies, Aug 2014, Paris, France. pp.65, ⟨10.1111/febs.12919⟩ Conference papers hal-02395537v1

	Synthesis and evaluations of uncharged reactivators for cholinesterases inhibited by organophosphate agents Anissa Braïki , Julien Renou , Romain Mougeot , Florian Nachon , André-Guilhem Calas International Conference on Chemical Biological Radiological and Nuclear agents (CBRN) - Research & Innovation (3, 2019), May 2019, Nantes, France Conference poster hal-02543439v1
	Synthesis and in vitro and in vivo evaluations of New Uncharged reactivators for cholinesterases inhibited by organophosphorus nerve agents Anissa Braïki , Julien Renou , Romain Mougeot , Florian Nachon , José Dias Medical Chemical Defense Conference (MCDC, 17, 2019), Mar 2019, Munich, Germany Conference poster hal-02543452v1
	Development of chemiluminescent probes for enzymatic activity detection. Steven Vertueux , Kathleen Solmont , Alexandre Haefele , Philippe Durand , Pierre-Yves Renard Journées du Groupement de recherche agents d'imagerie moléculaire (GDR AIM, 2, 2019), May 2019, Dijon, France Conference poster hal-02556313v1
	Development of chemiluminescent probes for enzymatic activity detection. Alexandre Haefele , Kathleen Solmont , Philippe Durand , Pierre-Yves Renard Journées du Groupement de recherche agents d'imagerie moléculaire (GDR AIM, 1, 2018), Jun 2018, Orléans, France Conference poster hal-02556312v1
	Development of a caspase-3 probe for apoptosis detection by dual optical-nuclear imaging Morgane Detraz , Alexandre Haefele , Pierre-Yves Renard , Pierre Bohn Rencontre ChiMi. Fluorescence : de la paillasse à l'utilisation clinique, Jan 2018, Dijon, France Conference poster hal-02556303v1
	Development of miniaturized fluorescence-based device for mycotoxin detection Dorra Gargouri , Abdelaaziz Ouahrouch , Alexandre Haefele , Julien Vieillard , Xavier Franck Journée de l’Ecole doctorale normande de chimie (JEDNC, 2018), Jun 2018, Rouen, France Conference poster hal-02556309v1
	Development of miniaturized fluorescence-based device for mycotoxin detection Dorra Gargouri , Abdelaaziz Ouahrouch , Alexandre Haefele , Julien Vieillard , Xavier Franck Rencontres en chimie organique biologique (RECOB, 17, 2018), Mar 2018, Aussois, France Conference poster hal-02556310v1
	Uncharged reactivators of cholinesterases inhibited by organophosphorus nerve agents. Nicolas Probst , Anissa Braïki , Pierre Warnault , Julien Renou , Catherine Gomez International Meeting on Cholinesterases (13, 2018) and International Conference on Paraoxonases (7, 2018)), Sep 2018, Hradec Králové, Czech Republic Conference poster hal-02543467v1
	Development of miniaturized fluorescence-based device for mycotoxin detection Dorra Gargouri , Abdelaaziz Ouahrouch , Alexandre Haefele , Julien Vieillard , Xavier Franck Journée de l’Ecole doctorale normande de chimie (JEDNC, 2017), Jun 2017, Rouen, France Conference poster hal-02556306v1
	Development of miniaturized fluorescence-based device for mycotoxin detection Dorra Gargouri , Abdelaaziz Ouahrouch , Alexandre Haefele , Julien Vieillard , Xavier Franck Journée Nord-Ouest Européennes des Jeunes Chercheurs et du Groupe Français des Polymères Grand Ouest (JNOEJC), Jun 2017, Caen, France Conference poster hal-02556308v1
	Development of a caspase-3 probe for apoptosis detection by dual optical-nuclear imaging Morgane Detraz , Alexandre Haefele , Pierre-Yves Renard , Pierre Bohn Journées de l’Ecole doctorale normande Biologie Intégrative, Santé, Environnement (EdN BISE, 20, 2017), Mar 2017, Le Havre, France Conference poster hal-02556299v1
	New Uncharged reactivators for cholinesterases inhibited by organophosphorus nerve agents Anissa Braïki , Julien Renou , Romain Mougeot , Tamara Zorbaz , André-Guilhem Calas International Conference on Chemical Biological Radiological nuclear Explosive - Research & Innovation (CBRNE, 2, 2017), May 2017, Lyon, France Conference poster hal-02544823v1
	Development of chemiluminescent probes for enzymatic activity detection. Kathleen Solmont , Virgile Grandclaude , Jean-Alexandre Richard , Alexandre Haefele , Philippe Durand International Caparica Conference on Chromogenic and Emissive Materials (I3CEM, 2, 2016), Sep 2016, Lisbonne, Portugal Conference poster hal-02556284v1
	Development of a caspase-3 probe for apoptosis detection bu dual optical-nuclear imaging M Detraz , Py Renard , P Vera , A Haefele , P Bohn IC3EM, Sep 2016, Caparica, Portugal Conference poster hal-01663947v1
	Synthesis of new uncharged reactivators for cholinesterases inhibited by organophosphorus nerve agents Anissa Braïki , Julien Renou , Catherine Gomez , Romain Mougeot , Florian Nachon Tetrahedron Symposium (17, 2016), Jun 2016, Barcelone, Spain Conference poster hal-02544884v1
	Development of a caspase-3 probe for apoptosis detection by dual optical-nuclear imaging Morgane Detraz , Alexandre Haefele , Pierre-Yves Renard , Pierre Bohn Journées de l’Ecole doctorale normande Biologie Intégrative, Santé, Environnement (EdN BISE, 19, 2016), Mar 2016, Caen, France Conference poster hal-02556291v1
	Development of chemiluminescent probes for enzymatic activity detection. Kathleen Solmont , Alexandre Haefele , Philippe Durand , Pierre-Yves Renard PSL Chemical Biology Symposium, Dec 2016, Paris, France Conference poster hal-02556279v1
	Development of chemiluminescent probes for enzymatic activity detection. Kathleen Solmont , Virgile Grandclaude , Jean-Alexandre Richard , Alexandre Haefele , Philippe Durand Anglo-Norman colloquium on organic chemistry (ANORCQ, 13, 2016), Apr 2016, Rouen, France Conference poster hal-02556286v1
	Development of a caspase-3 probe for apoptosis detection by dual optical-nuclear imaging Morgane Detraz , Alexandre Haefele , Pierre-Yves Renard , Pierre Bohn International Caparica Conference on Chromogenic and Emissive Materials (I3CEM, 2, 2016), Sep 2016, Lisbonne, Portugal Conference poster hal-02556296v1
	Development of a caspase-3 probe for apoptosis detection bu dual optical-nuclear imaging M Detraz , A Haefele , Py Renard , P Bohn Chemical Biology Symposium, Dec 2016, Paris, France Conference poster hal-01663935v1
	Development of chemiluminescent probes for enzymatic activity detection. Kathleen Solmont , Alexandre Haefele , Philippe Durand , Pierre-Yves Renard Journée de l’Ecole doctorale normande de chimie (JEDNC, 2016), Jun 2016, Caen, France Conference poster hal-02556287v1
	Multi Target directed ligands for the treatment of Alzheimer’s disease Sovy Chao , Killian Oukoloff , Monika Bouet , Diego Muñoz Torrero , Jacques-Philippe Colletier Rencontres internationales de chimie thérapeutique (RICT, 52, 2016), Jul 2016, Caen, France Conference poster hal-02544849v1
	Selective and Sensitive Near-Infrared Fluorescent Probe for Acetylcholinesterases Imaging Sovy Chao , Eric Krejci , Véronique Bernard , Jacqueline Leroy , Ludovic Jean International Symposium on Cholinergic Mechanisms (ISCM, 15, 2016), Oct 2016, Marseille, France Conference poster hal-02544874v1
	Uncharged Reactivators of cholinesterases Inhibited by organophosphorus nerve agents Pierre Warnault , Julien Renou , Catherine Gomez , Guillaume Mercey , Tristan Verdelet International Meeting on Cholinesterases - Sixth International Conference on Paraoxonases (12, 2015), Sep 2015, Elche, Spain Conference poster hal-02544902v1
	Design and Development of New Uncharged Reactivators of OP-Inhibited Cholinesterases Pierre Warnault , Julien Renou , Catherine Gomez , Guillaume Mercey , Tristan Verdelet International Conference on Chemical Biological Radiological and Nuclear agents (CBRN) - Research & Innovation (1, 2015), Mar 2015, Antibes, France Conference poster hal-02544917v1

	Phosphoryl compounds Pierre-Yves Renard , Christopher Timperley , Catherine Gomez Best Synthetic Methods: Organophosphorus (V), Academic press, pp.365-562, 2014, 978-0-08-098212-0. ⟨10.1016/C2011-0-04165-0⟩ Book sections hal-02345183v1

	Preparation of new nucleophile-reactive sulfonated compounds for the radiolabeling of biomolecules; precursors and conjugates thereof Thomas Priem , Cedric Bouteiller , David Camporese , Anthony Romieu , Pierre-Yves Renard France, Patent n° : WO 2014079979. 2014 Patents hal-01150298v1
	Composition and methods for the purification and production of butyrylcholinesterase. O. Lockridge, , M.A. Larson, , S.H. Schopfer, , S.H. Hinrichs, , Florian Nachon France, Patent n° : PCT/US14/66373. 2014 Patents hal-01150306v1
	Heterotetrafunctional reagents for bioconjugate chemistry Guillaume Viault , Sébastien Dautrey , Pierre-Yves Renard , Anthony Romieu France, Patent n° : EP14 50478. 2014 Patents hal-01150305v1
	Novel uncharged reactivators against OP-inhibition of human acetylcholinesterase Rachid Baati , Maria Klyachina , Valentin Nussbaum , Pierre-Yves Renard , Ludovic Jean France, Patent n° : EP13306584.7. 2013 Patents hal-01150304v1
	Labeled huprine derivatives and their use in medical imaging Cedric Bouteiller , Franco Mariani Maurizio , Cyril Ronco , Pierre-Yves Renard , Ludovic Jean France, Patent n° : WO 2011124713 A1. 2011 Patents hal-01150300v1
	Preparation of 7,11-Methanocycloocta[b]quinoline derivative as highly functionalizable acetylcholinesterase inhibitors for treating neurological diseases Cyril Ronco , Pierre-Yves Renard , Ludovic Jean , Florian Nachon , Anthony Romieu France, Patent n° : WO 2011124712 A1. 2011 Patents hal-01150301v1

Pierre-Yves renard

Publications

Light-Induced Unlocking Reactivity of Fragments for Fast Target-Guided Synthesis of Carbonic Anhydrase Inhibitors

Do Not Waste Time─Ensure Success in Your Cross-Linking Mass Spectrometry Experiments before You Begin

Revisiting the Chemistry and Photophysics of 3‐( N ‐Methylpyridinium‐4‐yl)Coumarins for Designing "Covalent‐Assembly" and "Molecular Disassembly" Fluorescent Probes

Biological response and cell death signaling pathways modulated by tetrahydroisoquinoline-based aldoximes in human cells

Design and Synthesis of Chemiluminescent Cassettes Based on Energy Transfer

Metalloenzyme‐Mediated Thiol‐Yne Addition Towards Photoisomerizable Fluorescent Dyes

A New Class of Bi- and Trifunctional Sugar Oximes as Antidotes against Organophosphorus Poisoning

Soft and effective detoxification of a VX simulant in a 3D printed basic flow reactor

Flow neutralisation of sulfur-containing chemical warfare agents with Oxone: packed-bed vs. aqueous solution

3-Benzoylquinoxalinone as a photoaffinity labelling derivative with fluorogenic properties allowing reaction monitoring under “no-wash” conditions

Tailored Bioorthogonal and Bioconjugate Chemistry: A Source of Inspiration for Developing Kinetic Target-Guided Synthesis Strategies

One-Pot Synthesis of Diazirines and 15N2-Diazirines from Ketones, Aldehydes and Derivatives: Development and Mechanistic Insight

Discovery of a Potent Dual Inhibitor of Acetylcholinesterase and Butyrylcholinesterase with Antioxidant Activity that Alleviates Alzheimer-like Pathology in Old APP/PS1 Mice

Maleimide-based metal-free ligation with dienes: a comparative study

Fluorophore-assisted click chemistry through copper(I) complexation

Functional characterization of multifunctional ligands targeting acetylcholinesterase and alpha 7 nicotinic acetylcholine receptor

Chromogranin A preferential interaction with Golgi phosphatidic acid induces membrane deformation and contributes to secretory granule biogenesis

Dearomatization of a 3-Hydroxypyridine through an unexpected Oxidative Deformylation Process: an Entry to Aza-cyclohexadienones

Pharmacokinetic Evaluation of Brain Penetrating Morpholine-3-hydroxy-2-pyridine Oxime as an Antidote for Nerve Agent Poisoning

Mono- and Poly-unsaturated Phosphatidic Acid Regulate Distinct Steps of Regulated Exocytosis in Neuroendocrine Cells

Investigation of tetrazine reactivity towards C-nucleophiles: pyrazolone-based modification of biomolecules

Regioselective Solid-Phase Synthesis of Peptide Analogues Containing 3,4- or 3,5-Disubstituted Isoxazole as s-cis or s-trans Peptide Bond Mimics

Real-time molecular optical micro-imaging of EGFR mutations using a fluorescent erlotinib based tracer

Reinvestigation of the synthesis of “covalent-assembly” type probes for fluoride ion detection. Identification of novel 7-(diethylamino)coumarins with aggregation-induced emission properties

Design, biological evaluation and X-ray crystallography of nanomolar multifunctional ligands targeting simultaneously acetylcholinesterase and glycogen synthase kinase-3

Toward an Innovative Treatment of Alzheimer’s Disease: Design of MTDLs Targeting Acetylcholinesterase and α-7 Nicotinic Receptors

Diverted Natural Lossen-type Rearrangement for Bioconjugation through in Situ Myrosinase-Triggered Isothiocyanate Synthesis

Detection of Biothiols with a Fast-Responsive and Water-Soluble Pyrazolone-Based Fluorogenic Probe

Combination delivery of two oxime-loaded lipid nanoparticles: Time-dependent additive action for prolonged rat brain protection

Bifunctional mannoside-glucosinolate glycoconjugates as enzymatically triggered isothiocyanates and FimH ligands

Use of an Air-Stable Cu(I)-NHC Catalyst for the Synthesis of Peptidotriazoles

Structure-Based Optimization of Nonquaternary Reactivators of Acetylcholinesterase Inhibited by Organophosphorus Nerve Agents

Potent 3‐Hydroxy‐2‐Pyridine Aldoxime Reactivators of Organophosphate‐Inhibited Cholinesterases with Predicted Blood–Brain Barrier Penetration

Covalent Modification of Biomolecules through Maleimide-Based Labeling Strategies

Increasing Polarity in Tacrine and Huprine Derivatives: Potent Anticholinesterase Agents for the Treatment of Myasthenia Gravis

A miniaturized peptidyl-prolyl isomerase enzyme assay

Selective and sensitive near‐infrared fluorescent probe for acetylcholinesterase imaging [abstract]

Regioselective synthesis of o-triazolyl-1,5-benzodiazepin-2-ones and o-isoxazolyl-1,5-benzodiazepin-2-ones via copper-catalyzed 1,3-dipolar cycloaddition reactions

Controlling Plasma Stability of Hydroxamic Acids: A MedChem Toolbox

An easy method for the determination of active concentrations of cholinesterase reactivators in blood samples: Application to the efficacy assessment of non quaternary reactivators compared to HI-6 and pralidoxime in VX-poisoned mice

Metal-free oxidative ring contraction of benzodiazepinones: an entry to quinoxalinones

On the Influence of the Protonation States of Active Site Residues on AChE Reactivation: A QM/MM Approach

Photophysical properties of quinoxalin-2(1H)-ones: Application in the preparation of an azide-based fluorogenic probe for the detection of hydrogen sulfide

Azo-based Fluorogenic Probes for Biosensing and Bioimaging: Recent Advances and Upcoming Challenges

Probing the cholinergic system to understand neurodegenerative diseases

Solution and solid-state fluorescence of 2-(2′-hydroxyphenyl)-1,5-benzodiazepin-2-one (HBD) borate complexes

1,5-Benzodiazepin-2-ones: Investigation of a Family of Photoluminescent Materials

Readily functionalizable phosphonium-tagged fluorescent coumarins for enhanced detection of conjugates by mass spectrometry

Synthesis and photophysical properties of iron-carbonyl complex–coumarin conjugates as potential bimodal IR–fluorescent probes

Improved Access to Huprine Derivatives Functionalized at Position 9

5-Alkoxyoxazole –A Versatile Building Block in (Bio)organic Synthesis

A selective and sensitive near-infrared fluorescent probe for acetylcholinesterase imaging

Fluorogenic Behaviour of the Hetero-Diels–Alder Ligation of 5-Alkoxyoxazoles with Maleimides and their Applications

Synthesis and in vitro evaluation of donepezil-based reactivators and analogues for nerve agent-inhibited human acetylcholinesterase

A FRET-​based probe for fluorescence sensing of sulfide​/sulfite analytes, using a novel long-​wavelength water-​soluble 7-​hydroxycoumarin as reporter fluorophore

Azobenzene-caged sulforhodamine dyes: A novel class of 'turn-on' reactive probes for hypoxic tumor cell imaging

Fast-Responsive Nitroso-Based Turn-On Probe for Hydrogen Sulfide

New insights into the kinetic target-guided synthesis of protein ligands

Synthetic Route to Rare Isoindolones Derivatives

A Synthetic Route to 3-​(Heteroaryl)​-​7-​hydroxycoumarins Designed for Biosensing Applications

Rapid Synthesis of Unsymmetrical Sulforhodamines Through Nucleophilic Amination of a Monobrominated Sulfoxanthene Dye

Rational Design of Latent Fluorophores from Water-​Soluble Hydroxyphenyltriazine Dyes Suitable for Lipase Sensing

PET and SPECT radiotracers for Alzheimer's disease

Multi-target directed ligands: Electrophysiological characterization of an anticholinesterase inhibitor coupled to an agonist of α7 nicotinic acetylcholine receptor

New 3-(Heteroaryl)-2-iminocoumarin-based Borate Complexes: Synthesis, Photophysical Properties, and Rational Functionalization for Biosensing/Biolabeling Applications

Design, synthesis and biological evaluation of novel tetrahydroacridine pyridine- aldoxime and -amidoxime hybrids as efficient uncharged reactivators of nerve agent-inhibited human acetylcholinesterase

Synthesis of fluorinated agonist of sphingosine-1-phosphate receptor 1

Kondrat'eva ligation: Diels-Alder-based irreversible reaction for bioconjugation

New insights into the water-​solubilization of thiol-​sensitive fluorogenic probes based on long-​wavelength 7-​hydroxycoumarin scaffolds

Straightforward synthesis of bioconjugatable azo dyes. Part 2: Black Hole Quencher-​2 (BHQ-​2) and BlackBerry Quencher 650 (BBQ-​650) scaffolds

Straightforward Access to Water-​Soluble Unsymmetrical Sulfoxanthene Dyes: Application to the Preparation of Far-​Red Fluorescent Dyes with Large Stokes' Shifts

Azo-Sulforhodamine Dyes: A Novel Class of Broad Spectrum Dark Quenchers

Metal-Free Decarboxylative Hetero-Diels-Alder Synthesis of 3-Hydroxypyridines: A Rapid Access to N-Fused Bicyclic Hydroxypiperidine Scaffolds.

Biochemical Characterization of a Caspase-3 Far-red Fluorescent Probe for Non-invasive Optical Imaging of Neuronal Apoptosis

Tryptoline-​3-​hydroxypyridinaldoxime conjugates as efficient reactivators of phosphylated human acetyl and butyrylcholinesterase

Straightforward synthesis of bioconjugatable azo dyes. Part 1: Black Hole Quencher-​1 (BHQ-​1) scaffold

Reaction site-driven regioselective synthesis of AChE inhibitors

First enzymatic hydrolysis/thio-Michael addition cascade route to synthesis of AChE inhibitors.

A FRET-based probe for fluorescence sensing of sulfide/sulfite analytes, using a novel long-wavelength water-soluble 7-hydroxycoumarin as reporter fluorophore

A Synthetic Route to 3-(Heteroaryl)-7-hydroxycoumarins Designed for Biosensing Applications

Rational Design of Latent Fluorophores from Water-Soluble Hydroxyphenyltriazine Dyes Suitable for Lipase Sensing

New insights into the water-solubilization of thiol-sensitive fluorogenic probes based on long-wavelength 7-hydroxycoumarin scaffolds

Straightforward synthesis of bioconjugatable azo dyes. Part 2: Black Hole Quencher-2 (BHQ-2) and BlackBerry Quencher 650 (BBQ-650) scaffolds

Straightforward Access to Water-Soluble Unsymmetrical Sulfoxanthene Dyes: Application to the Preparation of Far-Red Fluorescent Dyes with Large Stokes' Shifts

Tryptoline-3-hydroxypyridinaldoxime conjugates as efficient reactivators of phosphylated human acetyl and butyrylcholinesterase

Straightforward synthesis of bioconjugatable azo dyes. Part 1: Black Hole Quencher-1 (BHQ-1) scaffold