Pierre-Yves renard

Publications

Article dans une revue (153)

A pyronin-based “covalent-assembly” fluorescent probe for sensitive detection of cyanide in pure aqueous media and real water samples Vincent Gaumerd,Yoan Capello,Manhattan Lebrun,Michel Chalot,Pierre-Yves Renardet al. Talanta, 2026, 298, pp.128938. ⟨10.1016/j.talanta.2025.128938⟩ Article dans une revue hal-05496897v1
Designing New Natural‐Mimetic Phosphatidic Acid: A Versatile and Innovative Synthetic Strategy for Glycerophospholipid Research Antoine Schlichter,Alexander Wolf,Thomas Ferrand,Aurelien Cocq,Lina Riachyet al. Angewandte Chemie International Edition, 2025, 64 (36), ⟨10.1002/anie.202510412⟩ Article dans une revue hal-05245232v1
Assessment of cytotoxic properties of tetrahydroisoquinoline oximes in breast, prostate and glioblastoma cancer cells Antonio Zandona,Matea Jurić,Ludovic Jean,Pierre-Yves Renard,Maja Katalinić Drug and Chemical Toxicology, 2025, 48 (4), pp.856-863. ⟨10.1080/01480545.2025.2491534⟩ Article dans une revue hal-05496751v1
Fluorogenic detection of cyanide ions in pure aqueous media through an intramolecular crossed-benzoin reaction: limitations unveiled and possible solutions Vincent Gaumerd,Yoan Capello,Quentin Bonnin,Pierre-Yves Renard,Anthony Romieu Analyst, 2025, 150 (1), pp.168-176. ⟨10.1039/D4AN01368A⟩ Article dans une revue hal-04916512v1
Oxidative Neutralisation of Sulfur‐Based Chemical Warfare Agents Mediated by a Lipase: From Batch to Flow Reactor Maxime Boddaert,Valmir Baptista da Silva,Sergui Mansour,Daniela Vuluga,Pierre‐yves Renardet al. Chemistry - A European Journal, 2025, 31 (19), pp.e202403701. ⟨10.1002/chem.202403701⟩ Article dans une revue hal-05361291v1
Detoxification of chemical warfare agents at physiological pH using UiO-66(Zr)/gelatin hydrogel composite Subharanjan Biswas,Rémy Gay,Janek Bzdrenga,Thomas Soirot,Xavier Brazzolottoet al. ACS Applied Nano Materials, 2025, 8 (20), pp.10264-10274. ⟨10.1021/acsanm.4c06230⟩ Article dans une revue hal-05102269v1
Revisiting the Chemistry and Photophysics of 3‐( N ‐Methylpyridinium‐4‐yl)Coumarins for Designing &quot;Covalent‐Assembly&quot; and &quot;Molecular Disassembly&quot; Fluorescent Probes Vincent Gaumerd,Kévin Renault,Pierre‐yves Renard,Anthony Romieu ChemPhotoChem, 2024, 8 (5), ⟨10.1002/cptc.202300324⟩ Article dans une revue hal-04574555v1
Detoxification of V‐Nerve Agents Assisted by a Microperoxidase: New Pathway Revealed by the Use of a Relevant VX Simulant Valmir Baptista da Silva,Jean-Pierre Mahy,Xavier Brazzolotto,Pierre‐yves Renard,Rémy Ricouxet al. ChemBioChem, 2024, 25 (15), pp.e202400137. ⟨10.1002/cbic.202400137⟩ Article dans une revue hal-05500338v1
Light-Induced Unlocking Reactivity of Fragments for Fast Target-Guided Synthesis of Carbonic Anhydrase Inhibitors Chloé Puteaux,Isabelle Toubia,Lina Truong,Marie Hubert-Roux,Laetitia Baillyet al. Angewandte Chemie International Edition, 2024, 63 (41), ⟨10.1002/anie.202407888⟩ Article dans une revue hal-04788264v1
Do Not Waste Time─Ensure Success in Your Cross-Linking Mass Spectrometry Experiments before You Begin Lucienne Nouchikian,David Fernandez-Martinez,Pierre-Yves Renard,Cyrille Sabot,Guillaume Duménilet al. Analytical Chemistry, 2024, 96 (6), pp.2506 - 2513. ⟨10.1021/acs.analchem.3c04682⟩ Article dans une revue hal-04727678v1
Design and Synthesis of Chemiluminescent Cassettes Based on Energy Transfer Steven Vertueux,Alexandre Haefele,Kathleen Solmont,Philippe Durand,Pierre‐yves Renard European Journal of Organic Chemistry, 2023, 26 (13), pp.e202201401. ⟨10.1002/ejoc.202201401⟩ Article dans une revue hal-04059368v1
Biological response and cell death signaling pathways modulated by tetrahydroisoquinoline-based aldoximes in human cells Antonio Zandona,Josip Madunić,Katarina Miš,Nikola Maraković,Pierre Dubois-Geoffroyet al. Toxicology, 2023, 494, pp.153588. ⟨10.1016/j.tox.2023.153588⟩ Article dans une revue hal-04635900v1
Metalloenzyme‐Mediated Thiol‐Yne Addition Towards Photoisomerizable Fluorescent Dyes Alexis Lossouarn,Chloé Puteaux,Laetitia Bailly,Vincent Tognetti,Laurent Joubertet al. Chemistry - A European Journal, In press, ⟨10.1002/chem.202202180⟩ Article dans une revue hal-03808088v1
A New Class of Bi- and Trifunctional Sugar Oximes as Antidotes against Organophosphorus Poisoning Ophélie da Silva,Nicolas Probst,Christophe Landry,Anne-Sophie Hanak,Pierre Warnaultet al. Journal of Medicinal Chemistry, 2022, 65 (6), pp.4649-4666. ⟨10.1021/acs.jmedchem.1c01748⟩ Article dans une revue hal-03706969v1
Soft and effective detoxification of a VX simulant in a 3D printed basic flow reactor Sergui Mansour,Antonin Delaune,Maxime Manneveau,Baptiste Picard,Amélie Claudelet al. Green Chemistry, 2021, pp.7522-7527. ⟨10.1039/D1GC01961A⟩ Article dans une revue hal-03353830v1
One-Pot Synthesis of Diazirines and 15N2-Diazirines from Ketones, Aldehydes and Derivatives: Development and Mechanistic Insight Quentin Ibert,Madeleine Cauwel,Thomas Glachet,Tony Tite,Patricia Le Nahenec-Martelet al. Advanced Synthesis and Catalysis, 2021, 363 (18), pp.4390-4398. ⟨10.1002/adsc.202100679⟩ Article dans une revue hal-03331796v1
Tailored Bioorthogonal and Bioconjugate Chemistry: A Source of Inspiration for Developing Kinetic Target-Guided Synthesis Strategies Alexis Lossouarn,Pierre-Yves Renard,Cyrille Sabot Bioconjugate Chemistry, 2021, 32 (1), pp.63-72. ⟨10.1021/acs.bioconjchem.0c00568⟩ Article dans une revue hal-03419994v1
3-Benzoylquinoxalinone as a photoaffinity labelling derivative with fluorogenic properties allowing reaction monitoring under “no-wash” conditions Madeleine Cauwel,Clément Guillou,Kévin Renault,Damien Schapman,Magalie Bénardet al. Chemical Communications, 2021, 57 (32), pp.3893-3896. ⟨10.1039/D1CC01072G⟩ Article dans une revue hal-03419993v1
Flow neutralisation of sulfur-containing chemical warfare agents with Oxone: packed-bed vs. aqueous solution Antonin Delaune,Sergui Mansour,Baptiste Picard,Philippe Carrasqueira,Isabelle Chataigneret al. Green Chemistry, 2021, 23 (8), pp.2925-2930. ⟨10.1039/D1GC00449B⟩ Article dans une revue hal-03353823v1
Dearomatization of a 3-Hydroxypyridine through an unexpected Oxidative Deformylation Process: an Entry to Aza-cyclohexadienones Afef Mabrouki,Patricia Le Nahenec-Martel,Abdelkader Kriaa,Ahmed Hedhli,Pierre-Yves Renardet al. SYNLETT, 2020, 31 (15), pp.1497-1500. ⟨10.1055/s-0040-1706870⟩ Article dans une revue hal-03010593v1
Discovery of a Potent Dual Inhibitor of Acetylcholinesterase and Butyrylcholinesterase with Antioxidant Activity that Alleviates Alzheimer-like Pathology in Old APP/PS1 Mice Elisabet Viayna,Nicolas Coquelle,Monika Cieslikiewicz-Bouet,Pedro Cisternas,Carolina Olivaet al. Journal of Medicinal Chemistry, 2020, ⟨10.1021/acs.jmedchem.0c01775⟩ Article dans une revue hal-03094189v1
Chromogranin A preferential interaction with Golgi phosphatidic acid induces membrane deformation and contributes to secretory granule biogenesis Ophélie Carmon,Fanny Laguerre,Lina Riachy,Charlène Delestre-Delacour,Qili Wanget al. FASEB Journal, 2020, 34 (5), pp.6769-6790. ⟨10.1096/fj.202000074R⟩ Article dans une revue hal-02525074v1
Pharmacokinetic Evaluation of Brain Penetrating Morpholine-3-hydroxy-2-pyridine Oxime as an Antidote for Nerve Agent Poisoning Tamara Zorbaz,Petra Mišetić,Nicolas Probst,Suzana Žunec,Antonio Zandonaet al. ACS Chemical Neuroscience, 2020, 11 (7), pp.1072-1084. ⟨10.1021/acschemneuro.0c00032⟩ Article dans une revue hal-02505607v1
Mono- and Poly-unsaturated Phosphatidic Acid Regulate Distinct Steps of Regulated Exocytosis in Neuroendocrine Cells Émeline Tanguy,Pierre Costé de Bagneaux,Nawal Kassas,Mohamed-Raafet Ammar,Qili Wanget al. Cell Reports, 2020, 32 (7), pp.108026. ⟨10.1016/j.celrep.2020.108026⟩ Article dans une revue hal-02922310v1
Functional characterization of multifunctional ligands targeting acetylcholinesterase and alpha 7 nicotinic acetylcholine receptor Monika Cieslikiewicz-Bouet,Marina Naldi,Manuela Bartolini,Belén Pérez,Denis Serventet al. Biochemical Pharmacology, 2020, 177, ⟨10.1016/j.bcp.2020.114010⟩ Article dans une revue hal-02560260v1
Fluorophore-assisted click chemistry through copper(I) complexation Victor Flon,Magalie Bénard,Damien Schapman,Ludovic Galas,Pierre-Yves Renardet al. Biomolecules, 2020, Novel Approaches in Biomolecule Labeling, 10 (4), pp.619. ⟨10.3390/biom10040619⟩ Article dans une revue hal-03034414v1
Maleimide-based metal-free ligation with dienes: a comparative study Alexis Lossouarn,Kévin Renault,Laëtitia Bailly,Axel Frisby,Patricia Le Nahenec-Martelet al. Organic & Biomolecular Chemistry, 2020, 18 (20), pp.3874-3887. ⟨10.1039/D0OB00403K⟩ Article dans une revue hal-03010566v1
Real-time molecular optical micro-imaging of EGFR mutations using a fluorescent erlotinib based tracer Maxime Patout,Florian Guisier,Xavier Brune,Pierre Bohn,Anthony Romieuet al. BMC Pulmonary Medicine, 2019, 19, pp.3. ⟨10.1186/s12890-018-0760-z⟩ Article dans une revue hal-02353026v1
Investigation of tetrazine reactivity towards C-nucleophiles: pyrazolone-based modification of biomolecules Kévin Renault,Clément Guillou,Pierre-Yves Renard,Cyrille Sabot Organic & Biomolecular Chemistry, 2019, 17 (2), pp.388-396. ⟨10.1039/C8OB02108B⟩ Article dans une revue hal-02329641v1
Regioselective Solid-Phase Synthesis of Peptide Analogues Containing 3,4- or 3,5-Disubstituted Isoxazole as s-cis or s-trans Peptide Bond Mimics Pierrick Bruyat,Ludovic Jean,Pierre-Yves Renard European Journal of Organic Chemistry, 2019, 2019 (20), pp.3134-3141. ⟨10.1002/ejoc.201900378⟩ Article dans une revue hal-02319741v1
Reinvestigation of the synthesis of “covalent-assembly” type probes for fluoride ion detection. Identification of novel 7-(diethylamino)coumarins with aggregation-induced emission properties Valentin Quesneau,Benoît Roubinet,Pierre-Yves Renard,Anthony Romieu Tetrahedron Letters, 2019, 60 (48), pp.151279. ⟨10.1016/j.tetlet.2019.151279⟩ Article dans une revue hal-02320124v1
Design, biological evaluation and X-ray crystallography of nanomolar multifunctional ligands targeting simultaneously acetylcholinesterase and glycogen synthase kinase-3 Killian Oukoloff,Nicolas Coquelle,Manuela Bartolini,Marina Naldi,Rémy Le Guévelet al. European Journal of Medicinal Chemistry, 2019, 168, pp.58-77. ⟨10.1016/j.ejmech.2018.12.063⟩ Article dans une revue hal-02055769v1
Toward an Innovative Treatment of Alzheimer’s Disease: Design of MTDLs Targeting Acetylcholinesterase and α-7 Nicotinic Receptors Mégane Pons,Sylvie Chalon,Ludovic Jean,Pierre-Yves Renard,Frederic Buronet al. Proceedings, 2019, 22 (1), pp.88. ⟨10.3390/proceedings2019022088⟩ Article dans une revue hal-02352595v1
Potent 3‐Hydroxy‐2‐Pyridine Aldoxime Reactivators of Organophosphate‐Inhibited Cholinesterases with Predicted Blood–Brain Barrier Penetration Tamara Zorbaz,Anissa Braïki,Nikola Marakovic,Julien Renou,Eugenio de La Moraet al. Chemistry - A European Journal, 2018, 24 (38), pp.9675-9691. ⟨10.1002/chem.201801394⟩ Article dans une revue hal-02024542v1
Structure-Based Optimization of Nonquaternary Reactivators of Acetylcholinesterase Inhibited by Organophosphorus Nerve Agents Gianluca Santoni,J. de Sousa,Eugenio de La Mora,J. Dias,Ludovic Jeanet al. Journal of Medicinal Chemistry, 2018, 61 (17), pp.7630-7639. ⟨10.1021/acs.jmedchem.8b00592⟩ Article dans une revue hal-02024531v1
Covalent Modification of Biomolecules through Maleimide-Based Labeling Strategies Kévin Renault,J.W. Fredy,Pierre-Yves Renard,Cyrille Sabot Bioconjugate Chemistry, 2018, 29 (8), pp.2497-2513. ⟨10.1021/acs.bioconjchem.8b00252⟩ Article dans une revue hal-02024527v1
Bifunctional mannoside-glucosinolate glycoconjugates as enzymatically triggered isothiocyanates and FimH ligands G. Cutolo,F. Reise,M. Schuler,R. Nehmé,G. Despraset al. Organic & Biomolecular Chemistry, 2018, 16 (26), pp.4900-4913. ⟨10.1039/C8OB01128A⟩ Article dans une revue hal-02024493v1
Use of an Air-Stable Cu(I)-NHC Catalyst for the Synthesis of Peptidotriazoles Pierrick Bruyat,Arnaud Gautier,Ludovic Jean,Pierre-Yves Renard Journal of Organic Chemistry, 2018, 83 (21), pp.13515-13522. ⟨10.1021/acs.joc.8b01490⟩ Article dans une revue hal-01916360v1
Increasing Polarity in Tacrine and Huprine Derivatives: Potent Anticholinesterase Agents for the Treatment of Myasthenia Gravis Carles Galdeano,Nicolas Coquelle,Monika Cieslikiewicz-Bouet,Manuela Bartolini,Belén Pérezet al. Molecules, 2018, 23 (3), pp.634. ⟨10.3390/molecules23030634⟩ Article dans une revue hal-01807857v1
Combination delivery of two oxime-loaded lipid nanoparticles: Time-dependent additive action for prolonged rat brain protection T.N. Pashirova,Anissa Braïki,I.V. Zueva,K.A. Petrov,V.M. Babaevet al. Journal of Controlled Release, 2018, 290, pp.102-111. ⟨10.1016/j.jconrel.2018.10.010⟩ Article dans une revue hal-02024524v1
Detection of Biothiols with a Fast-Responsive and Water-Soluble Pyrazolone-Based Fluorogenic Probe Kévin Renault,Pierre-Yves Renard,Cyrille Sabot European Journal of Organic Chemistry, 2018, 2018 (46), pp.6494-6498. ⟨10.1002/ejoc.201801157⟩ Article dans une revue hal-02024529v1
Controlling Plasma Stability of Hydroxamic Acids: A MedChem Toolbox Paul Hermant,Damien Bosc,Catherine Piveteau,Ronan Gealageas,Baovy Lamet al. Journal of Medicinal Chemistry, 2017, 60 (21), pp.9067-9089. ⟨10.1021/acs.jmedchem.7b01444⟩ Article dans une revue hal-03054238v1
Regioselective synthesis of o-triazolyl-1,5-benzodiazepin-2-ones and o-isoxazolyl-1,5-benzodiazepin-2-ones via copper-catalyzed 1,3-dipolar cycloaddition reactions H. Mtiraoui,A. Nsira,M. Msaddek,Pierre-Yves Renard,Cyrille Sabot Comptes Rendus. Chimie, 2017, 20 (7), pp.747-757. ⟨10.1016/j.crci.2017.02.004⟩ Article dans une revue hal-02046301v1
Photophysical properties of quinoxalin-2(1H)-ones: Application in the preparation of an azide-based fluorogenic probe for the detection of hydrogen sulfide Kévin Renault,Pierre-Yves Renard,Cyrille Sabot New Journal of Chemistry, 2017, 41 (18), pp.10432-10437. ⟨10.1039/c7nj01893b⟩ Article dans une revue hal-02046306v1
Selective and sensitive near‐infrared fluorescent probe for acetylcholinesterase imaging [abstract] Pierre-Yves Renard,Ludovic Jean Journal of Neurochemistry, 2017, 142 (S2), pp.188-225. ⟨10.1111/jnc.13925⟩ Article dans une revue hal-02329887v1
On the Influence of the Protonation States of Active Site Residues on AChE Reactivation: A QM/MM Approach Thomas Driant,Florian Nachon,Cyril Ollivier,Pierre-Yves Renard,Etienne Derat ChemBioChem, 2017, 18 (7), pp.666-675. ⟨10.1002/cbic.201600646⟩ Article dans une revue hal-01644385v1
Metal-free oxidative ring contraction of benzodiazepinones: an entry to quinoxalinones Hasan Mtiraoui,Kévin Renault,Morgane Sanselme,Moncef Msaddek,Pierre-Yves Renardet al. Organic & Biomolecular Chemistry, 2017, 15 (14), pp.3060-3068. ⟨10.1039/C7OB00205J⟩ Article dans une revue hal-02329806v1
An easy method for the determination of active concentrations of cholinesterase reactivators in blood samples: Application to the efficacy assessment of non quaternary reactivators compared to HI-6 and pralidoxime in VX-poisoned mice André-Guilhem Calas,José Dias,Catherine Rousseau,Mélanie Arboléas,Mélanie Touvrey-Loiodiceet al. Chemico-Biological Interactions, 2017, 267 (1), pp.11-16. ⟨10.1016/j.cbi.2016.03.009⟩ Article dans une revue istex hal-02046266v1
Probing the cholinergic system to understand neurodegenerative diseases Pierre-Yves Renard,Ludovic Jean Future Medicinal Chemistry, 2017, 9 (2), pp.131-133. ⟨10.4155/fmc-2016-0213⟩ Article dans une revue hal-02046305v1
Azo-based Fluorogenic Probes for Biosensing and Bioimaging: Recent Advances and Upcoming Challenges Arnaud Chevalier,Pierre-Yves Renard,Anthony Romieu Chemistry - An Asian Journal, 2017, 12 (16), pp.2008-2028. ⟨10.1002/asia.201700682⟩ Article dans une revue hal-01562215v1
A miniaturized peptidyl-prolyl isomerase enzyme assay Mirella Vivoli,Julien Renou,Arnaud Chevalier,Isobel H. Norville,Suraya Diazet al. Analytical Biochemistry, 2017, 536, pp.59-68. ⟨10.1016/j.ab.2017.08.004⟩ Article dans une revue hal-02046314v1
Readily functionalizable phosphonium-tagged fluorescent coumarins for enhanced detection of conjugates by mass spectrometry Antoine Lizzul-Jurse,Laëtitia Bailly,Marie Hubert-Roux,Carlos Afonso,Pierre-Yves Renardet al. Organic & Biomolecular Chemistry, 2016, 14 (32), pp.7777-7791. ⟨10.1039/c6ob01080f⟩ Article dans une revue hal-02046223v1
5-Alkoxyoxazole –A Versatile Building Block in (Bio)organic Synthesis Laurie-Anne Jouanno,Kévin Renault,Cyrille Sabot,Pierre-Yves Renard European Journal of Organic Chemistry, 2016, 2016 (20), pp.3264-3281. ⟨10.1002/ejoc.201600127⟩ Article dans une revue istex hal-02046218v1
A selective and sensitive near-infrared fluorescent probe for acetylcholinesterase imaging Sovy Chao,Eric Krejci,Véronique Bernard,Jacqueline Leroy,Ludovic Jeanet al. Chemical Communications, 2016, 52 (77), pp.11599-11602. ⟨10.1039/c6cc05936h⟩ Article dans une revue hal-03013508v1
1,5-Benzodiazepin-2-ones: Investigation of a Family of Photoluminescent Materials Hasan Mtiraoui,Rafik Gharbi,Moncef Msaddek,Yann Bretonnière,Chantal Andraudet al. Journal of Organic Chemistry, 2016, 81 (11), pp.4720-4727. ⟨10.1021/acs.joc.6b00627⟩ Article dans une revue hal-01526233v1
Improved Access to Huprine Derivatives Functionalized at Position 9 Killian Oukoloff,Sovy Chao,Monika Cieslikiewicz-Bouet,Romain Mougeot,Ludovic Jeanet al. European Journal of Organic Chemistry, 2016, 2016 (7), pp.1337-1343. ⟨10.1002/ejoc.201501433⟩ Article dans une revue istex hal-02046230v1
Fluorogenic Behaviour of the Hetero-Diels–Alder Ligation of 5-Alkoxyoxazoles with Maleimides and their Applications Kévin Renault,Laurie-Anne Jouanno,Antoine Lizzul-Jurse,Pierre-Yves Renard,Cyrille Sabot Chemistry - A European Journal, 2016, 22 (51), pp.18522-18531. ⟨10.1002/chem.201603617⟩ Article dans une revue istex hal-02046236v1
Synthesis and in vitro evaluation of donepezil-based reactivators and analogues for nerve agent-inhibited human acetylcholinesterase Julien Renou,José Dias,Guillaume Mercey,Tristan Verdelet,Catherine Rousseauet al. RSC Advances, 2016, 6 (22), pp.17929-17940. ⟨10.1039/c5ra25477a⟩ Article dans une revue hal-02046237v1
Solution and solid-state fluorescence of 2-(2′-hydroxyphenyl)-1,5-benzodiazepin-2-one (HBD) borate complexes Hasan Mtiraoui,Rafik Gharbi,Moncef Msaddek,Yann Bretonnière,Chantal Andraudet al. RSC Advances, 2016, 6 (89), pp.86352-86360. ⟨10.1039/C6RA19246G⟩ Article dans une revue hal-01526238v1
Synthesis and photophysical properties of iron-carbonyl complex–coumarin conjugates as potential bimodal IR–fluorescent probes Paulina C. Glowacka,Nicolas Maindron,G. Richard Stephenson,Anthony Romieu,Pierre-Yves Renardet al. Tetrahedron Letters, 2016, 57 (45), pp.4991-4996. ⟨10.1016/j.tetlet.2016.09.091⟩ Article dans une revue hal-01428754v1
A FRET-​based probe for fluorescence sensing of sulfide​/sulfite analytes, using a novel long-​wavelength water-​soluble 7-​hydroxycoumarin as reporter fluorophore Benoît Roubinet,Laëtitia Bailly,Emilie Petit,Pierre-Yves Renard,Anthony Romieu Tetrahedron Letters, 2015, 56 (8), pp.1015-1019. ⟨10.1016/j.tetlet.2015.01.042⟩ Article dans une revue hal-01150270v1
Azobenzene-caged sulforhodamine dyes: A novel class of 'turn-on' reactive probes for hypoxic tumor cell imaging Arnaud Chevalier,Wen Piao,Kenjiro Hanaoka,Tetsuo Nagano,Pierre-Yves Renardet al. Methods and Applications in Fluorescence, 2015, 3 (4), pp.044004. ⟨10.1088/2050-6120/3/4/044004⟩ Article dans une revue hal-02046143v1
New insights into the kinetic target-guided synthesis of protein ligands E. Oueis,Cyrille Sabot,Pierre-Yves Renard Chemical Communications, 2015, 51 (61), pp.12158-12169. ⟨10.1039/c5cc04183j⟩ Article dans une revue hal-02046164v1
Multi-target directed ligands: Electrophysiological characterization of an anticholinesterase inhibitor coupled to an agonist of α7 nicotinic acetylcholine receptor Rómulo Aráoz,Monika Bouet,Manuela Bartolini,Nicolas Coquelle,Jacques-Philippe Colletieret al. Biochemical Pharmacology, 2015, 97 (4), pp.621. ⟨10.1016/j.bcp.2015.08.006⟩ Article dans une revue istex hal-02329901v1
Rapid Synthesis of Unsymmetrical Sulforhodamines Through Nucleophilic Amination of a Monobrominated Sulfoxanthene Dye Arnaud Chevalier,Kévin Renault,Frederic Boschetti,Pierre-Yves Renard,Anthony Romieu European Journal of Organic Chemistry, 2015, 2015 (1), pp.152-165. ⟨10.1002/ejoc.201403165⟩ Article dans une revue istex hal-01150274v1
PET and SPECT radiotracers for Alzheimer's disease Killian Oukoloff,Monika Cieslikiewicz-Bouet,Sovy Chao,Emilie da Costa Branquinho,C. Bouteilleret al. Current Medicinal Chemistry, 2015, 22 (28), pp.3278-3304. ⟨10.2174/0929867322666150805094645⟩ Article dans une revue hal-02046165v1
Rational Design of Latent Fluorophores from Water-​Soluble Hydroxyphenyltriazine Dyes Suitable for Lipase Sensing Alicia Jacquemet,Sandra Rihn,Gilles Ulrich,Pierre-Yves Renard,Anthony Romieuet al. European Journal of Organic Chemistry, 2015, 2015 (8), pp.1664-1669. ⟨10.1002/ejoc.201500047⟩ Article dans une revue istex hal-01150275v1
A Synthetic Route to 3-​(Heteroaryl)​-​7-​hydroxycoumarins Designed for Biosensing Applications Benoît Roubinet,Arnaud Chevalier,Pierre-Yves Renard,Anthony Romieu European Journal of Organic Chemistry, 2015, 2015 (1), pp.166-182. ⟨10.1002/ejoc.201403215⟩ Article dans une revue istex hal-01150273v1
Synthetic Route to Rare Isoindolones Derivatives Killian Oukoloff,Frederic Buron,Sylvain Routier,Ludovic Jean,Pierre-Yves Renard European Journal of Organic Chemistry, 2015, 2015 (11), pp.2450-2456. ⟨10.1002/ejoc.201403649⟩ Article dans une revue istex hal-01150276v1
New 3-(Heteroaryl)-2-iminocoumarin-based Borate Complexes: Synthesis, Photophysical Properties, and Rational Functionalization for Biosensing/Biolabeling Applications Benoît Roubinet,Cédrik Massif,Mathieu Moreau,F. Boschetti,Gilles Ulrichet al. Chemistry - A European Journal, 2015, 21 (41), pp.14589-14601. ⟨10.1002/chem.201502126⟩ Article dans une revue istex hal-02046171v1
Fast-Responsive Nitroso-Based Turn-On Probe for Hydrogen Sulfide Kévin Renault,Cyrille Sabot,Pierre-Yves Renard European Journal of Organic Chemistry, 2015, 2015 (36), pp.7992-7996. ⟨10.1002/ejoc.201501140⟩ Article dans une revue istex hal-02046170v1
Synthesis of fluorinated agonist of sphingosine-1-phosphate receptor 1 Lucie Aliouane,Sovy Chao,Brizuela Leyre,Emmanuel Pfund,Cuvillier Olivieret al. Bioorganic and Medicinal Chemistry, 2014, 22 (17), pp.4955-4960. ⟨10.1016/j.bmc.2014.06.038⟩ Article dans une revue istex hal-01063240v1
Design, synthesis and biological evaluation of novel tetrahydroacridine pyridine- aldoxime and -amidoxime hybrids as efficient uncharged reactivators of nerve agent-inhibited human acetylcholinesterase Maria Kliachyna,Gianluca Santoni,Valentin Nussbaum,Julien Renou,Benoît Sansonet al. European Journal of Medicinal Chemistry, 2014, 78, pp.455-467. ⟨10.1016/j.ejmech.2014.03.044⟩ Article dans une revue istex hal-01131268v1
Straightforward Access to Water-​Soluble Unsymmetrical Sulfoxanthene Dyes: Application to the Preparation of Far-​Red Fluorescent Dyes with Large Stokes' Shifts Arnaud Chevalier,Pierre-Yves Renard,Anthony Romieu Chemistry - A European Journal, 2014, 20 (27), pp.8330-8337. ⟨10.1002/chem.201402306⟩ Article dans une revue istex hal-01150280v1
Straightforward synthesis of bioconjugatable azo dyes. Part 2: Black Hole Quencher-​2 (BHQ-​2) and BlackBerry Quencher 650 (BBQ-​650) scaffolds Arnaud Chevalier,Pierre-Yves Renard,Anthony Romieu Tetrahedron Letters, 2014, 50 (55), pp.6764-6768. ⟨10.1016/j.tetlet.2014.10.054⟩ Article dans une revue hal-01150282v1
Tryptoline-​3-​hydroxypyridinaldoxime conjugates as efficient reactivators of phosphylated human acetyl and butyrylcholinesterase Julien Renou,Melanie Loiodice,Melanie Arboleas,Rachid Baati,Ludovic Jeanet al. Chemical Communications, 2014, 50 (30), pp.3947-3950. ⟨10.1039/C4CC00561A⟩ Article dans une revue hal-01150284v1
Biochemical Characterization of a Caspase-3 Far-red Fluorescent Probe for Non-invasive Optical Imaging of Neuronal Apoptosis Valérie Jolivel,Sébastien Arthaud,Béatrice Botia,Christophe Portal,Bruno Delestet al. Journal of Molecular Neuroscience, 2014, 54 (3), pp.451-462. ⟨10.1007/s12031-014-0325-4⟩ Article dans une revue hal-01196843v1
New insights into the water-​solubilization of thiol-​sensitive fluorogenic probes based on long-​wavelength 7-​hydroxycoumarin scaffolds Benoît Roubinet,Pierre-Yves Renard,Anthony Romieu Dyes and Pigments, 2014, 110, pp.270-284. ⟨10.1016/j.dyepig.2014.02.004⟩ Article dans une revue hal-01150279v1
Kondrat'eva ligation: Diels-Alder-based irreversible reaction for bioconjugation Laurie-Anne Jouanno,Arnaud Chevalier,Nawal Sekkat,Nicolas Perzo,Hélène Castelet al. Journal of Organic Chemistry, 2014, 79 (21), pp.10353-10366. ⟨10.1021/jo501972m⟩ Article dans une revue hal-01144842v1
Azo-Sulforhodamine Dyes: A Novel Class of Broad Spectrum Dark Quenchers Arnaud Chevalier,Pierre-Yves Renard,Anthony Romieu Organic Letters, 2014, 16 (15), pp.3946-3949. ⟨10.1021/ol501753b⟩ Article dans une revue hal-02335871v1
Metal-Free Decarboxylative Hetero-Diels-Alder Synthesis of 3-Hydroxypyridines: A Rapid Access to N-Fused Bicyclic Hydroxypiperidine Scaffolds. Laurie-Anne Jouanno,Vincent Di Mascio,Vincent Tognetti,Laurent Joubert,Cyrille Sabotet al. Journal of Organic Chemistry, 2014, 79 (3), pp.1303-1319. ⟨10.1021/jo402729a⟩ Article dans une revue hal-00996570v1
Reaction site-driven regioselective synthesis of AChE inhibitors Emilia Oueis,Gianluca Santoni,Cyril Ronco,Olga A. Syzgantseva,Vincent Tognettiet al. Organic & Biomolecular Chemistry, 2014, 12 (1), pp.156-161. ⟨10.1039/C3OB42109K⟩ Article dans une revue hal-02335933v1
Straightforward synthesis of bioconjugatable azo dyes. Part 1: Black Hole Quencher-​1 (BHQ-​1) scaffold Arnaud Chevalier,Pierre-Yves Renard,Anthony Romieu Tetrahedron Letters, 2014, 55 (50), pp.6759-6763. ⟨10.1016/j.tetlet.2014.10.053⟩ Article dans une revue hal-01150281v1
First enzymatic hydrolysis/thio-Michael addition cascade route to synthesis of AChE inhibitors. Emilia Oueis,Florian Nachon,Cyrille Sabot,Pierre-Yves Renard Chemical Communications, 2014, 50 (16), pp.2043-2045. ⟨10.1039/c3cc48871c⟩ Article dans une revue hal-00996567v1
Synthesis, biological evaluation, and in vivo imaging of the first camptothecin-fluorescein conjugate. Arnaud Chevalier,Martine Dubois,Vadim Le Joncour,Sébastien Dautrey,Céline Lecointreet al. Bioconjugate Chemistry, 2013, 24 (7), pp.1119-1133. ⟨10.1021/bc3005304⟩ Article dans une revue hal-00996547v1
Strategies for the selection of catalytic antibodies against organophosphorus nerve agents. Ivan Smirnov,Alexey Belogurov,Alain Friboulet,Patrick Masson,Alexander Gabibovet al. Chemico-Biological Interactions, 2013, 203 (1), pp.196-201. ⟨10.1016/j.cbi.2012.10.011⟩ Article dans une revue istex hal-00996534v1
Bioconjugatable azo-based dark-quencher dyes: synthesis and application to protease-activatable far-red fluorescent probes. Arnaud Chevalier,Cédrik Massif,Pierre-Yves Renard,Anthony Romieu Chemistry - A European Journal, 2013, 19 (5), pp.1686-1699. ⟨10.1002/chem.201203427⟩ Article dans une revue istex hal-00996530v1
The first comparative study of the ability of different hydrophilic groups to water-solubilize fluorescent BODIPY dyes Anthony Romieu,Cédrik Massif,Sandra Rihn,Gilles Ulrich,Raymond Ziesselet al. New Journal of Chemistry, 2013, 37 (4), pp.1016-1027. ⟨10.1039/C3NJ41093E⟩ Article dans une revue hal-01015523v1
Crystal structures of human cholinesterases in complex with huprine W and tacrine: elements of specificity for anti-Alzheimer's drugs targeting acetyl- and butyryl-cholinesterase. Florian Nachon,Eugénie Carletti,Cyril Ronco,Marie Trovaslet,Yvain Nicoletet al. Biochemical Journal, 2013, 453 (3), pp.393-399. ⟨10.1042/BJ20130013⟩ Article dans une revue hal-00996550v1
Universal dark quencher based on &quot;clicked&quot; spectrally distinct azo dyes. Arnaud Chevalier,Julie Hardouin,Pierre-Yves Renard,Anthony Romieu Organic Letters, 2013, 15 (23), pp.6082-6085. ⟨10.1021/ol402972y⟩ Article dans une revue hal-00996556v1
A novel sulfonated prosthetic group for [18F]-radiolabelling and imparting water solubility of biomolecules and cyanine fluorophores. Thomas Priem,Cédric Bouteiller,Davide Camporese,Xavier Brune,Julie Hardouinet al. Organic & Biomolecular Chemistry, 2013, 11 (3), pp.469-479. ⟨10.1039/c2ob26659h⟩ Article dans une revue hal-00996532v1
The first &quot;ready-to-use&quot; benzene-based heterotrifunctional cross-linker for multiple bioconjugation. Guillaume Viault,Sébastien Dautrey,Nicolas Maindron,Julie Hardouin,Pierre-Yves Renardet al. Organic & Biomolecular Chemistry, 2013, 11 (16), pp.2693-2705. ⟨10.1039/c3ob40086g⟩ Article dans une revue hal-00996541v1
Syntheses and in vitro evaluations of uncharged reactivators for human acetylcholinesterase inhibited by organophosphorus nerve agents. Julien Renou,Guillaume Mercey,Tristan Verdelet,Emilia Păunescu,Emilie Gillonet al. Chemico-Biological Interactions, 2013, 203 (1), pp.81-84. ⟨10.1016/j.cbi.2012.09.023⟩ Article dans une revue istex hal-00996535v1
The first latent green fluorophores for the detection of azoreductase activity in bacterial cultures. Arnaud Chevalier,Claire Mercier,Laura Saurel,Sylvain Orenga,Pierre-Yves Renardet al. Chemical Communications, 2013, 49 (78), pp.8815-8817. ⟨10.1039/c3cc44798g⟩ Article dans une revue hal-00996553v1
Correction to Expeditious Microwave-Assisted Synthesis of 5-Alkoxyoxazoles from α-Triflyloxy Esters and Nitriles Laurie-Anne Jouanno,Cyrille Sabot,Pierre‐yves Renard Journal of Organic Chemistry, 2013, 78 (4), pp.1706-1706. ⟨10.1021/jo400102n⟩ Article dans une revue hal-05504048v1
Radiosynthesis and in vivo evaluation of fluorinated huprine derivates as PET radiotracers of acetylcholinesterase Emilie da Costa Branquinho,Guillaume Becker,Cédric Bouteiller,Ludovic Jean,Pierre-Yves Renardet al. Nuclear Medicine and Biology, 2013, 40 (4), pp.554-560. ⟨10.1016/j.nucmedbio.2013.02.004⟩ Article dans une revue istex hal-00847401v1
Thermally controlled decarboxylative [4 + 2] cycloaddition between alkoxyoxazoles and acrylic acid: expedient access to 3-hydroxypyridines. Laurie-Anne Jouanno,Vincent Tognetti,Laurent Joubert,Cyrille Sabot,Pierre-Yves Renard Organic Letters, 2013, 15 (10), pp.2530-2533. ⟨10.1021/ol4010195⟩ Article dans une revue hal-00996416v1
Huprine derivatives as sub-nanomolar human acetylcholinesterase inhibitors: from rational design to validation by X-ray crystallography. Cyril Ronco,Eugénie Carletti,Jacques-Philippe Colletier,Martin Weik,Florian Nachonet al. ChemMedChem, 2012, 7 (3), pp.400-405. ⟨10.1002/cmdc.201100438⟩ Article dans une revue istex hal-00996475v1
Expeditious microwave-assisted synthesis of 5-alkoxyoxazoles from α-triflyloxy esters and nitriles. Laurie-Anne Jouanno,Cyrille Sabot,Pierre-Yves Renard Journal of Organic Chemistry, 2012, 77 (19), pp.8549-8555. ⟨10.1021/jo301527t⟩ Article dans une revue hal-00996502v1
Reactivators of acetylcholinesterase inhibited by organophosphorus nerve agents Guillaume Mercey,Tristan Verdelet,Julien Renou,Maria Kliachyna,Rachid Baatiet al. Accounts of Chemical Research, 2012, 45 (5), pp.756-766. ⟨10.1021/ar2002864⟩ Article dans une revue hal-01015972v1
Synthesis and reactivity of a bis-sultone cross-linker for peptide conjugation and [18F]-radiolabelling via unusual &quot;double click&quot; approach. Thomas Priem,Cédric Bouteiller,David Camporese,Anthony Romieu,Pierre-Yves Renard Organic & Biomolecular Chemistry, 2012, 10 (5), pp.1068-1078. ⟨10.1039/c1ob06600e⟩ Article dans une revue hal-00996479v1
Screening of new huprines--inhibitors of acetylcholinesterases by electrospray ionization ion trap mass spectrometry Anna Ziemianin,Cyril Ronco,Romain Dolé,Ludovic Jean,Pierre-Yves Renardet al. Journal of Pharmaceutical and Biomedical Analysis, 2012, 70, pp.1-5. ⟨10.1016/j.jpba.2012.01.038⟩ Article dans une revue istex hal-00996397v1
Phenyltetrahydroisoquinoline-pyridinaldoxime conjugates as efficient uncharged reactivators for the dephosphylation of inhibited human acetylcholinesterase. Guillaume Mercey,Julien Renou,Tristan Verdelet,Maria Kliachyna,Rachid Baatiet al. Journal of Medicinal Chemistry, 2012, 55 (23), pp.10791-10795. ⟨10.1021/jm3015519⟩ Article dans une revue hal-00996512v1
Water-soluble red-emitting distyryl-borondipyrromethene (BODIPY) dyes for biolabeling Song-Lin Niu,Cédrik Massif,Gilles Ulrich,Pierre-Yves Renard,Anthony Romieuet al. Chemistry - A European Journal, 2012, 18 (23), pp.7229-7242. ⟨10.1002/chem.201103613⟩ Article dans une revue istex hal-00996473v1
New insights into the water-solubilisation of fluorophores by post-synthetic &quot;click&quot; and Sonogashira reactions Cédrik Massif,Sébastien Dautrey,Alexandre Haefele,Raymond Ziessel,Pierre-Yves Renardet al. Organic & Biomolecular Chemistry, 2012, 10 (22), pp.4330-4336. ⟨10.1039/c2ob25428j⟩ Article dans une revue hal-00996469v1
Human butyrylcholinesterase produced in insect cells: huprine-based affinity purification and crystal structure. Xavier Brazzolotto,Marielle Wandhammer,Cyril Ronco,Marie Trovaslet,Ludovic Jeanet al. FEBS Journal, 2012, 279 (16), pp.2905-2916. ⟨10.1111/j.1742-4658.2012.08672.x⟩ Article dans une revue hal-00996490v1
Synthesis of polysubstituted 3-hydroxypyridines via the revisited hetero-Diels-Alder reaction of 5-alkoxyoxazoles with dienophiles. Cyrille Sabot,Emilia Oueis,Xavier Brune,Pierre-Yves Renard Chemical Communications, 2012, 48 (5), pp.768-770. ⟨10.1039/c1cc16562c⟩ Article dans une revue hal-00996467v1
Palladium-Catalyzed Preparation of N-Alkylated Tacrine and Huprine Compounds Cyril Ronco,Ludovic Jean,Hakim Outaabout,Pierre-Yves Renard European Journal of Organic Chemistry, 2011, 2011 (2), pp.302-310. ⟨10.1002/ejoc.201001158⟩ Article dans une revue istex hal-01017284v1
Synthesis and luminescence properties of new red-shifted absorption lanthanide(III) chelates suitable for peptide and protein labelling. Nicolas Maindron,Séverine Poupart,Maxime Hamon,Jean-Baptiste Langlois,Nelly Pléet al. Organic & Biomolecular Chemistry, 2011, 9 (7), pp.2357-2370. ⟨10.1039/c0ob00832j⟩ Article dans une revue hal-00991910v1
Synthesis of difluoromethylphosphonamidates by direct addition of amine Lucie Aliouane,Baptiste Rigaud,Emmanuel Pfund,Ludovic Jean,Pierre-Yves Renardet al. Tetrahedron Letters, 2011, 52 (28), pp.3681-3685. ⟨10.1016/j.tetlet.2011.05.034⟩ Article dans une revue istex hal-01017309v1
In Vitro and Ex Vivo Evaluation of Smart Infra-Red Fluorescent Caspase-3 Probes for Molecular Imaging of Cardiovascular Apoptosis Manuelle Debunne,Christophe Portal,Bruno Delest,Ebba Brakenhielm,Françoise Lallemandet al. International Journal of Molecular Imaging, 2011, 2011, pp.413290. ⟨10.1155/2011/413290⟩ Article dans une revue inserm-02296580v1
A novel and unusually long-lived chemiluminophore based on the 7-hydroxycoumarin scaffold. Jan Kočí,Virgile Grandclaude,Marc Massonneau,Jean-Alexandre Richard,Anthony Romieuet al. Chemical Communications, 2011, 47 (23), pp.6713-6715. ⟨10.1039/c1cc11919b⟩ Article dans une revue hal-00991904v1
N-Fmoc-α-sulfo-β-alanine: a versatile building block for the water solubilisation of chromophores and fluorophores by solid-phase strategy. Anthony Romieu,Thomas Bruckdorfer,Guillaume Clavé,Virgile Grandclaude,Cédrik Massifet al. Organic & Biomolecular Chemistry, 2011, 9 (15), pp.5337-5342. ⟨10.1039/c1ob05730h⟩ Article dans une revue hal-00991917v1
First efficient uncharged reactivators for the dephosphylation of poisoned human acetylcholinesterase. Guillaume Mercey,Tristan Verdelet,Géraldine Saint-André,Emilie Gillon,Alain Wagneret al. Chemical Communications, 2011, 47 (18), pp.5295-5297. ⟨10.1039/c1cc10787a⟩ Article dans une revue hal-00991912v1
New huprine derivatives functionalized at position 9 as highly potent acetylcholinesterase inhibitors. Cyril Ronco,Richard Foucault,Emilie Gillon,Pierre Bohn,Florian Nachonet al. ChemMedChem, 2011, 6 (5), pp.876-888. ⟨10.1002/cmdc.201000523⟩ Article dans une revue istex hal-00991920v1
A versatile access to new halogenated 7-azidocoumarins for photoaffinity labeling: Synthesis and photophysical properties Emilia Paunescu,Ludivine Louise,Ludovic Jean,Anthony Romieu,Pierre-Yves Renard Dyes and Pigments, 2011, 91 (3), pp.427-434. ⟨10.1016/j.dyepig.2011.05.008⟩ Article dans une revue istex hal-01017388v1
The first metal-free water-soluble cryptophane-111. Ténin Traoré,Guillaume Clavé,Léa Delacour,Naoko Kotera,Pierre-Yves Renardet al. Chemical Communications, 2011, 47 (34), pp.9702-9704. ⟨10.1039/c1cc13378k⟩ Article dans une revue hal-00991921v1
Optimized strategies to synthesize β-cyclodextrin-oxime conjugates as a new generation of organophosphate scavengers. Romain Le Provost,Timo Wille,Ludivine Louise,Nicolas Masurier,Susanne Mülleret al. Organic & Biomolecular Chemistry, 2011, 9 (8), pp.3026-3032. ⟨10.1039/c0ob00931h⟩ Article dans une revue hal-00991907v1
Water-solubilisation and bio-conjugation of a red-emitting BODIPY marker Song Lin Niu,Cédrik Massif,Gilles Ulrich,Raymond Ziessel,Pierre-Yves Renardet al. Organic & Biomolecular Chemistry, 2011, 9 (1), pp.66-69. ⟨10.1039/c0ob00693a⟩ Article dans une revue hal-00991914v1
Design, synthesis and evaluation of new alpha-nucleophiles for the hydrolysis of organophosphorus nerve agents: application to the reactivation of phosphorylated acetylcholinesterase Géraldine Saint-André,Maria Kliachyna,Sanjeevarao Kodepelly,Ludivine Louise-Leriche,Emilie Gillonet al. Tetrahedron, 2011, 67 (34), pp.6352-6361. ⟨10.1016/j.tet.2011.05.130⟩ Article dans une revue istex hal-01017442v1
Straightforward and efficient synthesis of 3-benzyloxy-4-bromopicolinate ester and 3-benzyloxy-5-bromopicolinate ester, common building blocks for pharmaceuticals and agrochemicals Tristan Verdelet,Guillaume Mercey,Nobi Correa,Ludovic Jean,Pierre-Yves Renard Tetrahedron, 2011, 67 (45), pp.8757-8762. ⟨10.1016/j.tet.2011.09.024⟩ Article dans une revue istex hal-01017528v1
A universal and ready-to-use heterotrifunctional cross-linking reagent for facile synthetic access to sophisticated bioconjugates. Guillaume Clavé,Hervé Volland,Mélanie Flaender,Didier Gasparutto,Anthony Romieuet al. Organic & Biomolecular Chemistry, 2010, 8 (19), pp.4329-4345. ⟨10.1039/c0ob00133c⟩ Article dans une revue istex hal-00991898v1
Improved synthetic pathway for the derivatization of huprine scaffold Cyril Ronco,Ludovic Jean,Pierre-Yves Renard Tetrahedron, 2010, 66 (37), pp.7399-7404. ⟨10.1016/j.tet.2010.07.021⟩ Article dans une revue istex hal-01019278v1
A HTS assay for the detection of organophosphorus nerve agent scavengers. Ludivine Louise-Leriche,Emilia Paunescu,Géraldine Saint-André,Rachid Baati,Anthony Romieuet al. Chemistry - A European Journal, 2010, 16 (11), pp.3510-3523. ⟨10.1002/chem.200902986⟩ Article dans une revue istex hal-00991892v1
Water solubilization of xanthene dyes by post-synthetic sulfonation in organic media Anthony Romieu,Delphine Tavernier-Lohr,S Pellet-Rostaing,Marc Lemaire,Pierre-Yves Renard Tetrahedron Letters, 2010, 51 (25), pp.3304-3308. ⟨10.1016/j.tetlet.2010.04.080⟩ Article dans une revue istex hal-01018665v1
Facile and rapid access to linear and truncated microcystin analogues for the implementation of immunoassays. G. Clavé,C. Ronco,H. Boutal,N. Kreich,H. Vollandet al. Organic & Biomolecular Chemistry, 2010, 8 (3), pp.676-690. ⟨10.1039/b920193a⟩ Article dans une revue istex hal-00991885v1
A comparative study of the self-immolation of para-aminobenzylalcohol and hemithioaminal-based linkers in the context of protease-sensitive fluorogenic probes. Yves Meyer,Jean-Alexandre Richard,Bruno Delest,Pauline Noack,Pierre-Yves Renardet al. Organic & Biomolecular Chemistry, 2010, 8 (8), pp.1777-1780. ⟨10.1039/b926316k⟩ Article dans une revue istex hal-00991894v1
A highly sensitive competitive enzyme immunoassay of broad specificity quantifying microcystins and nodularins in water samples Nathalie Khreich,Patricia Lamourette,Pierre-Yves Renard,Guillaume Clavé,François Fenailleet al. Toxicon, 2009, 53 (5), pp.551-559. ⟨10.1016/j.toxicon.2008.12.021⟩ Article dans une revue istex hal-05504060v1
Synthesis and structure–activity relationship of Huprine derivatives as human acetylcholinesterase inhibitors Cyril Ronco,Geoffroy Sorin,Florian Nachon,Richard Foucault,Ludovic Jeanet al. Bioorganic and Medicinal Chemistry Letters, 2009, 17 (13), pp.4523-4536. ⟨10.1016/j.bmc.2009.05.005⟩ Article dans une revue istex hal-03808202v1
Additions and Corrections Pierre-Yves Renard Organic & Biomolecular Chemistry, 2009, 7 (24), pp.5271. ⟨10.1039/b922697b⟩ Article dans une revue istex hal-03808190v1
Synthesis of a (+)-anatoxin-a analogue for monoclonal antibodies production Mickael Marc,Francis Outurquin,Pierre-Yves Renard,Christophe Créminon,Xavier Franck Tetrahedron Letters, 2009, 50 (31), pp.4554-4557. ⟨10.1016/j.tetlet.2009.05.094⟩ Article dans une revue istex hal-05504052v1
Water-Soluble BODIPY Derivatives Song Lin Niu,Gilles Ulrich,Raymond Ziessel,Agneta Kiss,Pierre-Yves Renardet al. Organic Letters, 2009, 11 (10), pp.2049-2052. ⟨10.1021/ol900302n⟩ Article dans une revue hal-05504058v1
Self-cleavable chemiluminescent probes suitable for protease sensing Jean-Alexandre Richard,Ludovic Jean,Caroline Schenkels,Marc Massonneau,Anthony Romieuet al. Organic & Biomolecular Chemistry, 2009, 7 (14), pp.2941. ⟨10.1039/b905725k⟩ Article dans une revue istex hal-03808199v1
Thyroid hormone improves postischaemic recovery of function while limiting apoptosis: a new therapeutic approach to support hemodynamics in the setting of ischaemia-reperfusion? Constantinos Pantos,Iordanis Mourouzis,Theodosios Saranteas,Guillaume Clavé,Heidi Ligeretet al. Basic Research in Cardiology, 2009, 104 (1), pp.69-77. ⟨10.1007/s00395-008-0758-4⟩ Article dans une revue istex hal-05504050v1
Synthesis and structure–activity relationship of Huprine derivatives as human acetylcholinesterase inhibitors Cyril Ronco,Geoffroy Sorin,Florian Nachon,Richard Foucault,Ludovic Jeanet al. Bioorganic and Medicinal Chemistry, 2009, 17 (13), pp.4523-4536. ⟨10.1016/j.bmc.2009.05.005⟩ Article dans une revue istex hal-05504054v1
Straightforward Access to Protected syn α‐Amino‐β‐hydroxy Acid Derivatives Jignesh Patel,Guillaume Clavé,Pierre‐yves Renard,Xavier Franck Angewandte Chemie International Edition, 2008, 47 (22), pp.4224-4227. ⟨10.1002/anie.200800860⟩ Article dans une revue istex hal-05504070v1
A novel heterotrifunctional peptide-based cross-linking reagent for facile access to bioconjugates. Applications to peptide fluorescent labelling and immobilisation Guillaume Clavé,Hervé Boutal,Antoine Hoang,François Perraut,Hervé Vollandet al. Organic & Biomolecular Chemistry, 2008, 6 (17), pp.3065. ⟨10.1039/b807263a⟩ Article dans une revue istex hal-05504064v1
Additions and corrections Pierre-Yves Renard,Anthony Romieu,S. Poupart,Philippe A. Peixoto Organic & Biomolecular Chemistry, 2008, 6 (24), pp.4668. ⟨10.1039/b819176j⟩ Article dans une revue istex hal-05504066v1
Postsynthetic Derivatization of Fluorophores with α-Sulfo-β-alanine Dipeptide Linker. Application to the Preparation of Water-Soluble Cyanine and Rhodamine Dyes Anthony Romieu,Dominique Brossard,Maxime Hamon,Hakim Outaabout,Christophe Portalet al. Bioconjugate Chemistry, 2008, 19 (1), pp.279-289. ⟨10.1021/bc7003268⟩ Article dans une revue istex hal-05504069v1
Latent Fluorophores Based on a Self-Immolative Linker Strategy and Suitable for Protease Sensing Jean-Alexandre Richard,Yves Meyer,Valérie Jolivel,Marc Massonneau,Raphaël Dumeunieret al. Bioconjugate Chemistry, 2008, 19 (8), pp.1707-1718. ⟨10.1021/bc8001997⟩ Article dans une revue istex hal-05504068v1
Development of a New Nonpeptidic Self-Immolative Spacer. Application to the Design of Protease Sensing Fluorogenic Probes Yves Meyer,Jean-Alexandre Richard,Marc Massonneau,Pierre-Yves Renard,Anthony Romieu Organic Letters, 2008, 10 (8), pp.1517-1520. ⟨10.1021/ol800198f⟩ Article dans une revue hal-05504067v1
7-Hydroxycoumarin−Hemicyanine Hybrids: A New Class of Far-Red Emitting Fluorogenic Dyes Jean-Alexandre Richard,Marc Massonneau,Pierre-Yves Renard,Anthony Romieu Organic Letters, 2008, 10 (19), pp.4175-4178. ⟨10.1021/ol801582w⟩ Article dans une revue hal-05504063v1
Novel Water-Soluble Near-Infrared Cyanine Dyes: Synthesis, Spectral Properties, and Use in the Preparation of Internally Quenched Fluorescent Probes Cédric Bouteiller,Guillaume Clavé,Aude Bernardin,Bertrand Chipon,Marc Massonneauet al. Bioconjugate Chemistry, 2007, 18 (4), pp.1303-1317. ⟨10.1021/bc0700281⟩ Article dans une revue istex hal-05504072v1
Chemiluminescent Probe for the in Vitro Detection of Protease Activity Jean-Alexandre Richard,Ludovic Jean,Anthony Romieu,Marc Massonneau,Pauline Noack-Fraissigneset al. Organic Letters, 2007, 9 (23), pp.4853-4855. ⟨10.1021/ol702190y⟩ Article dans une revue hal-05504071v1
Aminopropargyl derivative of terpyridine-bis(methyl-enamine) tetraacetic acid chelate of europium (Eu (TMT)-AP3): a new reagent for fluorescent labelling of proteins and peptides Séverine Poupard,Cédric Boudou,Philippe Peixoto,Marc Massonneau,Pierre-Yves Renardet al. Organic & Biomolecular Chemistry, 2006, 4 (22), pp.4165. ⟨10.1039/b612805j⟩ Article dans une revue istex hal-05504073v1
Latent fluorophores based on a Mannich cyclisation trigger Guillaume Clavé,Aude Bernardin,Marc Massonneau,Pierre-Yves Renard,Anthony Romieu Tetrahedron Letters, 2006, 47 (35), pp.6229-6233. ⟨10.1016/j.tetlet.2006.06.138⟩ Article dans une revue istex hal-05504038v1
Aryldithioethyloxycarbonyl(Ardec) : a new family of aminoe protecting groups removable under mild reducing conditions and their applications to peptide synthesis. M. Lapeyre,Jérôme Leprince,M. Massonneau,Hassan Oulyadi,Pierre-Yves Renardet al. Chemistry - A European Journal, 2006, 12, pp.3655-3671 Article dans une revue hal-00023718v1
Aryldithioethyloxycarbonyl (Ardec): A New Family of Amine Protecting Groups Removable under Mild Reducing Conditions and Their Applications to Peptide Synthesis Milaine Lapeyre,Jérôme Leprince,Marc Massonneau,Hassan Oulyadi,Pierre-Yves Renardet al. Chemistry - A European Journal, 2006, 12 (13), pp.3655-3671. ⟨10.1002/chem.200501538⟩ Article dans une revue istex hal-01962803v1
Synthesis and post-synthetic derivatization of a cyanine-based amino acid. Application to the preparation of a novel water-soluble NIR dye Bertrand Chipon,Guillaume Clavé,Cédric Bouteiller,Marc Massonneau,Pierre-Yves Renardet al. Tetrahedron Letters, 2006, 47 (47), pp.8279-8284. ⟨10.1016/j.tetlet.2006.09.100⟩ Article dans une revue istex hal-05504091v1
Immunologically driven antibodies chemical engineering: design and synthesis of a hapten aimed at nerve agent hydrolysis Florence Jovic,Ludivine Louise,Charles Mioskowski,Pierre-Yves Renard Tetrahedron Letters, 2005, 46 (40), pp.6809-6814. ⟨10.1016/j.tetlet.2005.08.032⟩ Article dans une revue istex hal-05504029v1
Lewis Acid Catalyzed Room-Temperature Michaelis–Arbuzov Rearrangement Pierre-Yves Renard,Philippe Vayron,Eric Leclerc,Alain Valleix,Charles Mioskowski Angewandte Chemie International Edition, 2003, 42 (21), pp.2389-2392. ⟨10.1002/anie.200250270⟩ Article dans une revue istex hal-02345149v1
Design and Synthesis of Chemiluminescent Probes for the Detection of Cholinesterase Activity Stéphane Sabelle,Pierre-Yves Renard,Karine Pecorella,Sophie de Suzzoni-Dézard,Christophe Créminonet al. Journal of the American Chemical Society, 2002, 124 (17), pp.4874-4880. ⟨10.1021/ja0171299⟩ Article dans une revue istex hal-05504025v1
Stereoselective access to polyfunctionalized decalins Cyrille Poirel,P.Y. Renard,J.Y. Lallemand Tetrahedron Letters, 1994, 35 (35), pp.6485-6488 Article dans une revue hal-02710197v1

Communication dans un congrès (28)

Neurosecretion Is Finely Tuned by Molecular Actors Sorted at the Golgi Membrane Level in Neuroendocrine Cells Thomas Ferrand,Alexander Wolf,Fanny Laguerre,Lina Riachy,Antoine Schlichteret al. 46ème Colloque de La Société de Neuroendocrinologie, Sep 2024, Nice, France Communication dans un congrès hal-05163699v1
Chromogranin A and Phosphatidic Acid: A Protein/Phospholipid Interaction Regulating Neurosecretion Thomas Ferrand,Alexander Wolf,Fanny Laguerre,Lina Riachy,Antoine Schlichteret al. Club Exocytose-Endocytose, Nov 2024, Montpellier, France Communication dans un congrès hal-05163698v1
Secretory Granule Biogenesis Is Initiated by Chromogranin A Interaction with Phosphatidic Acid Fanny Laguerre,Lina Riachy,Ophélie Carmon,Charlène Delestre-Delacour,Qili Wanget al. 20th International Symposium on Chromaffin Cell Biology, Jan 2020, Chennai, India Communication dans un congrès hal-05156996v1
Multi-target drug Ligands design and synthesis for Alzheimer disease backed by X-ray crystal analyses Pierre-Yves Renard Annual Conference of AnalytiX (7, 2019), Nov 2019, Berlin, Germany Communication dans un congrès hal-02404227v1
Sondes pro-fluorescentes et chémiluminescentes pour la détection d'analyses d'intérêt biologique Pierre-Yves Renard Séminaire national, Institut Brestois Santé Agro Matière (IBSAM), May 2019, Brest, France Communication dans un congrès hal-02404291v1
Overview of 3-hydroxy-pyridindaldoxime based reactivators Pierre-Yves Renard International workshop on nerve agents, North Atlantic Treaty Organisation (NATO), Nov 2018, Paris, France Communication dans un congrès hal-02403935v1
Sondes fluorogéniques pour la détection d'activités enzymatiques et d'analytes d'intérêt biologiques Pierre-Yves Renard Séminaire national, Institut des biomolécules Max Mousseron (IBMM, UMR 5247), Oct 2018, Montpellier, France Communication dans un congrès hal-02393849v1
Chimiluminescence in vivo Pierre-Yves Renard Rencontre ChiMi. Fluorescence : de la paillasse à l'utilisation clinique, Jan 2018, Dijon, France Communication dans un congrès hal-02395824v1
Réactions de ligation fluorogéniques Pierre-Yves Renard Journées scientifiques de chémobiologie, Nov 2018, Lille, France Communication dans un congrès hal-02389306v1
Fluorogenic Behaviour of the Hetero-Diels-Alder Ligation of 5-Alkoxyoxazoles with Maleimides and their Applications Pierre-Yves Renard International Caparica Conference on Chromogenic and Emissive Materials (3, 2018), Jun 2018, Lisbonne, Portugal Communication dans un congrès hal-02388673v1
Pro-fluorescent and chemiluminescent probes for enzymatic activities detection Pierre-Yves Renard Séminaire national, Laboratoire des biomolécules (LBM, UMR 7203), May 2018, Paris, France Communication dans un congrès hal-02393089v1
Méthode de criblage : identification de catalyseurs de la réaction de Diels-Alder Cyrille Sabot,Laura Nogueira de Faria Cardoso,Pierre-Yves Renard,Wadih Ghattas,Jean-Pierre Mahy Journée scientifique du LabEx Chimie des Architectures Moléculaires Multifonctionnelles et des Matériaux (CHARMMMAT, 6, 2018)), Jun 2018, Cachan, France Communication dans un congrès hal-03098307v1
Méthode de criblage : identification de catalyseurs de la réaction de Diels-Alder Cyrille Sabot,Laura Nogueira de Faria Cardoso,Pierre-Yves Renard,Wadih Ghattas,Jean-Pierre Mahy Journée scientifique du LabEx Chimie des Architectures Moléculaires Multifonctionnelles et des Matériaux (CHARMMMAT, 6, 2018)), Jun 2018, Cachan, France Communication dans un congrès hal-02372510v1
The effects of organophosphorus compounds and novel antidotes on human neuronal cells T. Zorbaz,M. Katalinic,I. Pavicic,Anissa Braïki,J. Renouet al. International Symposium on Cholinergic Mechanisms (ISCM, 15, 2016), Oct 2016, Marseille, France. pp.224-225 Communication dans un congrès hal-02024991v1
Selective and sensitive near-infrared fluorescent probe for acetylcholinesterase imaging Sovy Chao,Ludovic Jean,E. Krejci,Pierre-Yves Renard International Symposium on Cholinergic Mechanisms (ISCM, 15, 2017), Oct 2016, Marseille, France. pp.209, ⟨10.1111/jnc.13925⟩ Communication dans un congrès hal-02024977v1
Hupresin, a new affinity resin to purify butyrylcholinesterase E. David,C. Ronco,Ludovic Jean,X. Brazzolotto,F. Nachonet al. International Symposium on Cholinergic Mechanisms (ISCM, 15, 2017), Oct 2016, Marseille, France. pp.210, ⟨10.1111/jnc.13925⟩ Communication dans un congrès hal-02024979v1
Novel centrally active antidote for intoxication by sarin and VX nerve agents T. Zorbaz,M. Katalinic,A. Zandona,Anissa Braïki,Ludovic Jeanet al. Congress of the Federation-of-European-Biochemical-Societies (FEBS) on From Molecules to Cells and Back (42, 2017), Sep 2017, Jérusalem, Israel. pp.242, ⟨10.1111/febs.14174⟩ Communication dans un congrès hal-02024992v1
Toward an innovative treatment of Alzheimer's disease: Synthesis and evaluation of multi-target directed ligands (MTDLs) targeting acetylcholinesterase (AChE) and alpha7 nicotinic acetylchloline receptors (alpha7 nAChRs) Monika Cieslikiewicz-Bouet,Sovy Chao,Ludovic Jean,R. Araoz,D. Serventet al. International Symposium on Cholinergic Mechanisms (ISCM, 15, 2016), Oct 2016, Marseille, France. pp.209-210 Communication dans un congrès hal-02024978v1
Heterotrifunctionnal linkers for bioconjugate reactions Pierre-Yves Renard The Missing link biologically driven ligation of carbohydrates and proteins, Jun 2016, Kiel, Germany Communication dans un congrès hal-02389804v1
L'acétylcholinestérase Pierre-Yves Renard Séminaire industriel, Servier, Mar 2016, Croissy-sur-Seine, France Communication dans un congrès hal-02391648v1
Exemples d'utilisation de sondes fluorescentes pour détecter l'évolution et les impacts de traitements antitumoraux Pierre-Yves Renard Journée de présentation et d´échanges Chimie, Biologie et Cancer dans l´inter-région Nord-Ouest, Apr 2016, Amiens, France Communication dans un congrès hal-02395831v1
New oximes for OP poisoned cholinesterases reactivation Pierre-Yves Renard International workshop on chemical warfare agents: toxicity, emergency response and medical countermeasures, Sep 2016, Paris, France Communication dans un congrès hal-02388800v1
Dynamic mapping of acetylcholinesterase for structural-dynamics based reactivator design G. Santoni,E. de La Mora,J.-P. Colletier,Ludovic Jean,Y. Xuet al. 12th International Meeting on Cholinesterases, Sep 2015, Elche, Spain Communication dans un congrès hal-02024984v1
Water soluble unsymmetrical sulfoxanthene dyes - access to a novel class of broad spectrum dark quenchers Pierre-Yves Renard International Caparica Conference on Chromogenic and Emissive Materials (2, 2016), Sep 2016, Lisbonne, Portugal Communication dans un congrès hal-02388670v1
Pro-fluorescent and chemiluminescent probes for enzymatic activities detection Pierre-Yves Renard Séminaire national, Institut de chimie de Nice (ICN, UMR 7272), Mar 2016, Nice, France Communication dans un congrès hal-02393073v1
Insights on two in situ click chemistry reactions for the synthesis of AChE inhibitors E. Oueis,Ronco C.,F. Nachon,Cyrille Sabot,Ludovic Jeanet al. International Meeting on Cholinesterases - Sixth International Conference on Paraoxonases (12, 2015), Sep 2015, Elche, Spain Communication dans un congrès hal-02379142v1
L'acétylcholinestérase : une enzyme modèle pour le chimiste bio-organicien Pierre-Yves Renard Séminaire national, Institut de chimie moléculaire de l'Université de Bourgogne (ICMUB, UMR 6302), Apr 2015, Dijon, France Communication dans un congrès hal-02391659v1
Evaluation of three novel hydroxypicolinaldehyde oximes as efficient uncharged reactivators of VX-inhibited human acetylcholinesterase Z. Kovarik,M. Katalinic,Ludovic Jean,Pierre-Yves Renard,Renou J.et al. FEBS-EMBO Anniversary Conference, Federation of European Biochemical Societies, Aug 2014, Paris, France. pp.65, ⟨10.1111/febs.12919⟩ Communication dans un congrès hal-02395537v1

Poster de conférence (27)

Chromogranin A / Phosphatidic Acid Interaction Is Crucial for the Neurosecretory Pathway, from Biogenesis to Fusion of Secretory Granules Thomas Ferrand,Alexander Wolf,Fanny Laguerre,Lina Riachy,Antoine Schlichteret al. 26th Annual Meeting of the Club Exocytose-Endocytose, Apr 2024, Sète, France. 2024 Poster de conférence hal-05168288v1
Neurohormone Secretion Requires Chromogranin A / Phosphatidic Acid Interaction at the Level of Neuroendocrine Cell Membranes Thomas Ferrand,Marine Courvalet,Lina Riachy,Fanny Laguerre,Lydie Jeandelet al. Journée Normande de Recherche Biomédicale, Jun 2022, Rouen, France. 2022 Poster de conférence hal-05164769v1
Synthesis and in vitro and in vivo evaluations of New Uncharged reactivators for cholinesterases inhibited by organophosphorus nerve agents Anissa Braïki,Julien Renou,Romain Mougeot,Florian Nachon,José Diaset al. Medical Chemical Defense Conference (MCDC, 17, 2019), Mar 2019, Munich, Germany Poster de conférence hal-02543452v1
Development of chemiluminescent probes for enzymatic activity detection. Steven Vertueux,Kathleen Solmont,Alexandre Haefele,Philippe Durand,Pierre-Yves Renard Journées du Groupement de recherche agents d'imagerie moléculaire (GDR AIM, 2, 2019), May 2019, Dijon, France Poster de conférence hal-02556313v1
Synthesis and evaluations of uncharged reactivators for cholinesterases inhibited by organophosphate agents Anissa Braïki,Julien Renou,Romain Mougeot,Florian Nachon,André-Guilhem Calaset al. International Conference on Chemical Biological Radiological and Nuclear agents (CBRN) - Research & Innovation (3, 2019), May 2019, Nantes, France Poster de conférence hal-02543439v1
Development of chemiluminescent probes for enzymatic activity detection. Alexandre Haefele,Kathleen Solmont,Philippe Durand,Pierre-Yves Renard Journées du Groupement de recherche agents d'imagerie moléculaire (GDR AIM, 1, 2018), Jun 2018, Orléans, France Poster de conférence hal-02556312v1
Development of miniaturized fluorescence-based device for mycotoxin detection Dorra Gargouri,Abdelaaziz Ouahrouch,Alexandre Haefele,Julien Vieillard,Xavier Francket al. Rencontres en chimie organique biologique (RECOB, 17, 2018), Mar 2018, Aussois, France Poster de conférence hal-02556310v1
Development of a caspase-3 probe for apoptosis detection by dual optical-nuclear imaging Morgane Detraz,Alexandre Haefele,Pierre-Yves Renard,Pierre Bohn Rencontre ChiMi. Fluorescence : de la paillasse à l'utilisation clinique, Jan 2018, Dijon, France Poster de conférence hal-02556303v1
Development of miniaturized fluorescence-based device for mycotoxin detection Dorra Gargouri,Abdelaaziz Ouahrouch,Alexandre Haefele,Julien Vieillard,Xavier Francket al. Journée de l’Ecole doctorale normande de chimie (JEDNC, 2018), Jun 2018, Rouen, France Poster de conférence hal-02556309v1
Uncharged reactivators of cholinesterases inhibited by organophosphorus nerve agents. Nicolas Probst,Anissa Braïki,Pierre Warnault,Julien Renou,Catherine Gomezet al. International Meeting on Cholinesterases (13, 2018) and International Conference on Paraoxonases (7, 2018)), Sep 2018, Hradec Králové, Czech Republic Poster de conférence hal-02543467v1
Development of a caspase-3 probe for apoptosis detection by dual optical-nuclear imaging Morgane Detraz,Alexandre Haefele,Pierre-Yves Renard,Pierre Bohn Journées de l’Ecole doctorale normande Biologie Intégrative, Santé, Environnement (EdN BISE, 20, 2017), Mar 2017, Le Havre, France Poster de conférence hal-02556299v1
Development of miniaturized fluorescence-based device for mycotoxin detection Dorra Gargouri,Abdelaaziz Ouahrouch,Alexandre Haefele,Julien Vieillard,Xavier Francket al. Journée Nord-Ouest Européennes des Jeunes Chercheurs et du Groupe Français des Polymères Grand Ouest (JNOEJC), Jun 2017, Caen, France Poster de conférence hal-02556308v1
New Uncharged reactivators for cholinesterases inhibited by organophosphorus nerve agents Anissa Braïki,Julien Renou,Romain Mougeot,Tamara Zorbaz,André-Guilhem Calaset al. International Conference on Chemical Biological Radiological nuclear Explosive - Research & Innovation (CBRNE, 2, 2017), May 2017, Lyon, France Poster de conférence hal-02544823v1
Development of miniaturized fluorescence-based device for mycotoxin detection Dorra Gargouri,Abdelaaziz Ouahrouch,Alexandre Haefele,Julien Vieillard,Xavier Francket al. Journée de l’Ecole doctorale normande de chimie (JEDNC, 2017), Jun 2017, Rouen, France Poster de conférence hal-02556306v1
Development of chemiluminescent probes for enzymatic activity detection. Kathleen Solmont,Virgile Grandclaude,Jean-Alexandre Richard,Alexandre Haefele,Philippe Durandet al. International Caparica Conference on Chromogenic and Emissive Materials (I3CEM, 2, 2016), Sep 2016, Lisbonne, Portugal Poster de conférence hal-02556284v1
Development of a caspase-3 probe for apoptosis detection by dual optical-nuclear imaging Morgane Detraz,Alexandre Haefele,Pierre-Yves Renard,Pierre Bohn International Caparica Conference on Chromogenic and Emissive Materials (I3CEM, 2, 2016), Sep 2016, Lisbonne, Portugal Poster de conférence hal-02556296v1
Development of chemiluminescent probes for enzymatic activity detection. Kathleen Solmont,Alexandre Haefele,Philippe Durand,Pierre-Yves Renard Journée de l’Ecole doctorale normande de chimie (JEDNC, 2016), Jun 2016, Caen, France Poster de conférence hal-02556287v1
Multi Target directed ligands for the treatment of Alzheimer’s disease Sovy Chao,Killian Oukoloff,Monika Bouet,Diego Muñoz Torrero,Jacques-Philippe Colletieret al. Rencontres internationales de chimie thérapeutique (RICT, 52, 2016), Jul 2016, Caen, France Poster de conférence hal-02544849v1
Development of chemiluminescent probes for enzymatic activity detection. Kathleen Solmont,Virgile Grandclaude,Jean-Alexandre Richard,Alexandre Haefele,Philippe Durandet al. Anglo-Norman colloquium on organic chemistry (ANORCQ, 13, 2016), Apr 2016, Rouen, France Poster de conférence hal-02556286v1
Development of a caspase-3 probe for apoptosis detection bu dual optical-nuclear imaging M Detraz,A Haefele,Py Renard,P Bohn Chemical Biology Symposium, Dec 2016, Paris, France Poster de conférence hal-01663935v1
Selective and Sensitive Near-Infrared Fluorescent Probe for Acetylcholinesterases Imaging Sovy Chao,Eric Krejci,Véronique Bernard,Jacqueline Leroy,Ludovic Jeanet al. International Symposium on Cholinergic Mechanisms (ISCM, 15, 2016), Oct 2016, Marseille, France Poster de conférence hal-02544874v1
Development of a caspase-3 probe for apoptosis detection by dual optical-nuclear imaging Morgane Detraz,Alexandre Haefele,Pierre-Yves Renard,Pierre Bohn Journées de l’Ecole doctorale normande Biologie Intégrative, Santé, Environnement (EdN BISE, 19, 2016), Mar 2016, Caen, France Poster de conférence hal-02556291v1
Development of chemiluminescent probes for enzymatic activity detection. Kathleen Solmont,Alexandre Haefele,Philippe Durand,Pierre-Yves Renard PSL Chemical Biology Symposium, Dec 2016, Paris, France Poster de conférence hal-02556279v1
Development of a caspase-3 probe for apoptosis detection bu dual optical-nuclear imaging M Detraz,Py Renard,P Vera,A Haefele,P Bohn IC3EM, Sep 2016, Caparica, Portugal Poster de conférence hal-01663947v1
Synthesis of new uncharged reactivators for cholinesterases inhibited by organophosphorus nerve agents Anissa Braïki,Julien Renou,Catherine Gomez,Romain Mougeot,Florian Nachonet al. Tetrahedron Symposium (17, 2016), Jun 2016, Barcelone, Spain Poster de conférence hal-02544884v1
Design and Development of New Uncharged Reactivators of OP-Inhibited Cholinesterases Pierre Warnault,Julien Renou,Catherine Gomez,Guillaume Mercey,Tristan Verdeletet al. International Conference on Chemical Biological Radiological and Nuclear agents (CBRN) - Research & Innovation (1, 2015), Mar 2015, Antibes, France Poster de conférence hal-02544917v1
Uncharged Reactivators of cholinesterases Inhibited by organophosphorus nerve agents Pierre Warnault,Julien Renou,Catherine Gomez,Guillaume Mercey,Tristan Verdeletet al. International Meeting on Cholinesterases - Sixth International Conference on Paraoxonases (12, 2015), Sep 2015, Elche, Spain Poster de conférence hal-02544902v1

Chapitre d'ouvrage (1)

Phosphoryl compounds Pierre-Yves Renard,Christopher Timperley,Catherine Gomez Best Synthetic Methods: Organophosphorus (V), Academic press, pp.365-562, 2014, 978-0-08-098212-0. ⟨10.1016/C2011-0-04165-0⟩ Chapitre d'ouvrage hal-02345183v1

Brevet (9)

Glycérophospholipides synthétiques comprenant au moins une fonction réactive, leur procédé de préparation et leurs utilisations dans différentes applications Sebastien Balieu,Pierre-Yves Renard,Maite Montero-Hadjadje,Nicolas Vitale,Aurélien Cocqet al. France, N° de brevet: FR3133855 (A1). 2023 Brevet hal-05156784v1
Synthetic glycerophospholipids comprising at least one reactive function, process for preparing same and uses thereof Pierre-Yves Renard,Sebastien Balieu,Maite Montero-Hadjadje,Nicolas Vitale,Aurélien Cocqet al. France, Patent n° : WO2023180457. 2023 Brevet hal-05496833v1
CARBALDEHYDE OXIMES AS BUTYRYLCHOLINESTERASE REACTIVATORS Pierre-Yves Renard,Ludovic Jean,Nicolas Probst,Anissa Braïki,Pierre Dubois-Geoffroyet al. France, Patent n° : WO 2022023315. 2022 Brevet hal-05496848v1
Composition and methods for the purification and production of butyrylcholinesterase. O. Lockridge,,M.A. Larson,,S.H. Schopfer,,S.H. Hinrichs,,Florian Nachonet al. France, Patent n° : PCT/US14/66373. 2014 Brevet hal-01150306v1
Preparation of new nucleophile-​reactive sulfonated compounds for the radiolabeling of biomolecules; precursors and conjugates thereof Thomas Priem,Cedric Bouteiller,David Camporese,Anthony Romieu,Pierre-Yves Renard France, Patent n° : WO 2014079979. 2014 Brevet hal-01150298v1
Heterotetrafunctional reagents for bioconjugate chemistry Guillaume Viault,Sébastien Dautrey,Pierre-Yves Renard,Anthony Romieu France, Patent n° : EP14 50478. 2014 Brevet hal-01150305v1
Novel uncharged reactivators against OP-inhibition of human acetylcholinesterase Rachid Baati,Maria Klyachina,Valentin Nussbaum,Pierre-Yves Renard,Ludovic Jeanet al. France, Patent n° : EP13306584.7. 2013 Brevet hal-01150304v1
Preparation of 7,​11-​Methanocycloocta[b]​quinoline derivative as highly functionalizable acetylcholinesterase inhibitors for treating neurological diseases Cyril Ronco,Pierre-Yves Renard,Ludovic Jean,Florian Nachon,Anthony Romieu France, Patent n° : WO 2011124712 A1. 2011 Brevet hal-01150301v1
Labeled huprine derivatives and their use in medical imaging Cedric Bouteiller,Franco Mariani Maurizio,Cyril Ronco,Pierre-Yves Renard,Ludovic Jeanet al. France, Patent n° : WO 2011124713 A1. 2011 Brevet hal-01150300v1

Pré-publication, Document de travail (1)

Chromogranin A regulates the dynamics of neurosecretion through its interaction with phosphatidic acid Thomas Ferrand,Alexander Wolf,Fanny Laguerre,Lina Riachy,Antoine Schlichteret al. 2026 Pré-publication, Document de travail hal-05496862v1