Pablo VARGAS Group leader &quot;Leukomotion Lab&quot;

Publications

Article dans une revue (31)

Kinesin-1 coordinates cross-talk between microtubule and actin cytoskeletons during dendritic cell migration Pierre Duquesne,Céline Aoun,Mathieu Kurowska,Brieuc Perot,Kerui Zhanget al. Science Advances , 2025, 11 (42), pp.eadx7672. ⟨10.1126/sciadv.adx7672⟩ Article dans une revue hal-05326533v1
Lamin A/C Expression in Hematopoietic Cells Declines During Human Aging and Constrains Atherosclerosis in Mice Marta Amorós-Pérez,Alberto del Monte-Monge,Pilar Gonzalo,María J Andrés-Manzano,Cristina Riuset al. Arteriosclerosis, Thrombosis, and Vascular Biology, 2025, 45, pp.1616 - 1635. ⟨10.1161/atvbaha.124.322893⟩ Article dans une revue hal-05551694v1
Human inherited CCR2 deficiency underlies progressive polycystic lung disease Anna-Lena Neehus,Brenna Carey,Marija Landekic,Patricia Panikulam,Gail Deutschet al. Cell, 2024, 187 (2), pp.390-408.e23. ⟨10.1016/j.cell.2023.11.036⟩ Article dans une revue hal-04701934v1
Actin dynamics regulation by TTC7A/PI4KIIIα limits DNA damage and cell death under confinement Tania Gajardo,Mathilde Bernard,Marie Lô,Elisa Turck,Claire Leveauet al. Journal of Allergy and Clinical Immunology, 2023, 152 (4), pp.949-960. ⟨10.1016/j.jaci.2023.06.016⟩ Article dans une revue hal-04279730v1
DOCK11 deficiency in patients with X-linked actinopathy and autoimmunity Charlotte Boussard,Laure Delage,Tania Gajardo,Alexandre Kauskot,Maxime Batigneset al. Blood, 2023 Article dans une revue hal-04246983v1
DOCK11 deficiency in patients with X-linked actinopathy and autoimmunity Charlotte Boussard,Laure Delage,Tania Gajardo,Alexandre Kauskot,Maxime Batigneset al. Blood, 2023, ⟨10.1182/blood.2022018486⟩ Article dans une revue hal-04455529v1
The tumor suppressor adenomatous polyposis coli regulates T lymphocyte migration Marta Mastrogiovanni,Pablo Vargas,Thierry Rose,Céline Cuche,Elric Espositoet al. Science Advances , 2022, 8 (15), pp.eabl5942. ⟨10.1126/sciadv.abl5942⟩ Article dans une revue pasteur-03681845v1
Atypical CXCL12 signaling enhances neutrophil migration by modulating nuclear deformability Bianca Calì,Mathieu Deygas,Fabio Munari,Elisabetta Marcuzzi,Antonino Cassaráet al. Science Signaling, 2022, 15 (761), ⟨10.1126/scisignal.abk2552⟩ Article dans une revue (data paper) hal-04290477v1
Rubella vaccine–induced granulomas are a novel phenotype with incomplete penetrance of genetic defects in cytotoxicity Miriam Gross,Carsten Speckmann,Annette May,Tania Gajardo-Carrasco,Katharina Wustrauet al. Journal of Allergy and Clinical Immunology, In press, ⟨10.1016/j.jaci.2021.05.007⟩ Article dans une revue hal-03432275v1
Pinching the cortex of live cells reveals thickness instabilities caused by myosin II motors Valentin Laplaud,Nicolas Levernier,Judith Pineau,Mabel San,Lucie Barbieret al. Science Advances , 2021 Article dans une revue hal-03395597v1
Pinching the cortex of live cells reveals thickness instabilities caused by myosin II motors Valentin Laplaud,Nicolas Levernier,Judith Pineau,Lucie Barbier,Pablo J Sáezet al. Science Advances , 2021, 7 (27), pp.eabe3640. ⟨10.1126/sciadv.abe3640⟩ Article dans une revue hal-03278532v1
Predicting Confined 1D Cell Migration from Parameters Calibrated to a 2D Motor-Clutch Model Louis S Prahl,Maria R Stanslaski,Pablo Vargas,Matthieu Piel,David J Odde Biophysical Journal, 2020, 118 (7), pp.1709-1720. ⟨10.1016/j.bpj.2020.01.048⟩ Article dans une revue hal-03036509v1
Deterministic actin waves as generators of cell polarization cues Luiza Stankevicins,Nicolas Ecker,Emmanuel Terriac,Paolo Maiuri,Rouven Schoppmeyeret al. Proceedings of the National Academy of Sciences of the United States of America, 2020, 117 (2), pp.826-835. ⟨10.1073/pnas.1907845117⟩ Article dans une revue hal-03697356v1
A statistical inference approach to reconstruct intercellular interactions in cell migration experiments Elena Agliari,Pablo J Sáez,Adriano Barra,Matthieu Piel,Pablo Vargaset al. Science Advances , 2020, 6 (11), pp.eaay2103. ⟨10.1126/sciadv.aay2103⟩ Article dans une revue hal-03036516v1
Sliding walls: a new paradigm for fluidic actuation and protocol implementation in microfluidics Bastien Venzac,Yang Liu,Ivan Ferrante,Pablo Vargas,Ayako Yamadaet al. Microsystems & Nanoengineering, 2020, 6 (1), ⟨10.1038/s41378-019-0125-7⟩ Article dans une revue hal-03041894v2
Myosin II Activity Is Selectively Needed for Migration in Highly Confined Microenvironments in Mature Dendritic Cells Lucie Barbier,Pablo J Sáez,Rafaele Attia,Ana-Maria Lennon-Duménil,Ido Laviet al. Frontiers in Immunology, 2019, 10 (10), pp.993-1004. ⟨10.3389/fimmu.2019.00747⟩ Article dans une revue hal-02466630v1
Reconstitution of cell migration at a glance Juan Manuel Garcia-Arcos,Renaud Chabrier,Mathieu Deygas,Guilherme Nader,Lucie Barbieret al. Journal of Cell Science, 2019, 132 (4), pp.jcs225565. ⟨10.1242/jcs.225565⟩ Article dans une revue hal-02466691v1
Role of calcium permeable channels in dendritic cell migration Pablo J Sáez,Juan Sáez,Ana-Maria Lennon-Duménil,Pablo Vargas Current Opinion in Immunology, 2018, 52 (1), pp.74-80. ⟨10.1016/j.coi.2018.04.005⟩ Article dans une revue hal-02466785v1
Innate Immune Signals Induce Anterograde Endosome Transport Promoting MHC Class I Cross-Presentation Mirjana Weimershaus,Francois-Xavier Mauvais,Loredana Saveanu,Cézaire Adiko,Joel Babdoret al. Cell Reports, 2018, 24 (13), pp.3568-3581. ⟨10.1016/j.celrep.2018.08.041⟩ Article dans une revue hal-02466698v1
Diversification of human plasmacytoid predendritic cells in response to a single stimulus Solana Alculumbre,Violaine Saint-André,Jérémy Di Domizio,Pablo Vargas,Philemon Sirvenet al. Nature Immunology, 2018, 19 (1), pp.63-75. ⟨10.1038/s41590-017-0012-z⟩ Article dans une revue hal-02349815v1
Diversification of human plasmacytoid predendritic cells in response to a single stimulus. Solana G. Alculumbre,Violaine Saint-André,Jeremy Di Domizio,Pablo Vargas,Philemon Sirvenet al. Nature immunology, 2018, 19, pp.63--75 Article dans une revue hal-04024846v1
A tuneable microfluidic system for long duration chemotaxis experiments in a 3D collagen matrix Koceila Aizel,Andrew Clark,Anthony Simon,Sara Geraldo,Anette Funfaket al. Lab on a Chip, 2017, 17 (22), pp.3851-3861. ⟨10.1039/C7LC00649G⟩ Article dans une revue hal-04788653v1
UNC93B1 interacts with the calcium sensor STIM1 for efficient antigen cross-presentation in dendritic cells Sophia Maschalidi,Paula Nunes-Hasler,Clarissa Nascimento,Ignacio Sallent,Valérie Lannoyet al. Nature Communications, 2017, 8 (1), ⟨10.1038/s41467-017-01601-5⟩ Article dans une revue hal-02365944v1
UNC93B1 interacts with the calcium sensor STIM1 for efficient antigen cross-presentation in dendritic cells Sophia Maschalidi,Paula Nunes-Hasler,Clarissa R Nascimento,Ignacio Sallent,Valérie Lannoyet al. Nature Communications, 2017, 8 (1), pp.1640. ⟨10.1038/s41467-017-01601-5⟩ Article dans une revue hal-04059179v1
UNC93B1 interacts with the calcium sensor STIM1 for efficient antigen cross-presentation in dendritic cells Sophia Maschalidi,Paula Nunes-Hasler,Clarissa R Nascimento,Ignacio Sallent,Valérie Lannoyet al. Nature Communications, 2017, 8, ⟨10.1038/s41467-017-01601-5⟩ Article dans une revue hal-03103691v1
Perinuclear Arp2/3-driven actin polymerization enables nuclear deformation to facilitate cell migration through complex environments Hawa-Racine Thiam,Pablo Vargas,Nicolas Carpi,Carolina Lage Crespo,Matthew Raabet al. Nature Communications, 2016, 7 (1), pp.10997. ⟨10.1038/ncomms10997⟩ Article dans une revue hal-05551260v1
Space exploration by dendritic cells requires maintenance of myosin II activity by IP3 receptor 1. Paola Solanes,Mélina L Heuzé,Mathieu Maurin,Marine Bretou,Franziska Lautenschlaegeret al. EMBO Journal, 2015, 34 (6), pp.798-810. ⟨10.15252/embj.201489056⟩ Article dans une revue hal-02947479v1
Cell migration and antigen capture are antagonistic processes coupled by myosin II in dendritic cells Mélanie Chabaud,Mélina L Heuzé,Marine Bretou,Pablo Vargas,Paolo Maiuriet al. Nature Communications, 2015, 6 (1), pp.7526. ⟨10.1038/ncomms8526⟩ Article dans une revue hal-05551261v1
The actin-based motor protein myosin II regulates MHC class II trafficking and BCR-driven antigen presentation. Fulvia Vascotto,Danielle Lankar,Gabrielle Faure-André,Pablo Vargas,Jheimmy Diazet al. Journal of Cell Biology, 2007, 176 (7), pp.1007-19. ⟨10.1083/jcb.200611147⟩ Article dans une revue hal-00316389v1
NOX2 Controls Phagosomal pH to Regulate Antigen Processing during Crosspresentation by Dendritic Cells Ariel Savina,Carolina Jancic,Stephanie Hugues,Pierre Guermonprez,Pablo Vargaset al. Cell, 2006, 126, pp.205 - 218. ⟨10.1016/j.cell.2006.05.035⟩ Article dans une revue hal-05551675v1
Immunization with antigen-pulsed dendritic cells significantly improves the immune response to weak self-antigens Pablo Vargas,Claudio Cortés,Leonardo Vargas,Mario Rosemblatt,María Rosa Bono Immunobiology, 2006, 211, pp.29 - 36. ⟨10.1016/j.imbio.2005.09.002⟩ Article dans une revue hal-05551681v1

Chapitre d'ouvrage (1)

Leukocyte Migration and Deformation in Collagen Gels and Microfabricated Constrictions Pablo J Sáez,Lucie Barbier,Rafaele Attia,Hawa-Racine Thiam,Matthieu Pielet al. Methods in molecular biology, pp.361-373, 2018, ⟨10.1007/978-1-4939-7701-7_26⟩ Chapitre d'ouvrage hal-02467714v1

Pré-publication, Document de travail (3)

Torque-based immune cell chemotaxis in complex environments Theresa Jakuszeit,Mathieu Deygas,Mathilde Bernard,Aastha Mathur,Li Wanget al. 2025 Pré-publication, Document de travail hal-05401063v1
Adaptive motility enables neutrophils to rapidly navigate confined capillaries Mathieu Deygas,Mathilde Bernard,Pierre Nivoit,Lucie Barbier,Li Wanget al. 2025 Pré-publication, Document de travail hal-05401067v1
Super-resolved live imaging of thick biological samples with 3D Random Illumination Microscopy (3D-RIM) Thomas Mangeat,Lorry Mazzella,Benoît Rogez,Guillaume Giroussens,Xiangyi Liet al. 2025 Pré-publication, Document de travail hal-05283147v1