Rafael ARGUELLO

Identifiants chercheurs

IdHAL :

rafael-arguello

ORCID :

0000-0001-9785-3883

Publications

Article dans une revue (48)

VPS34-IN1 potentiates STING-dependent activation in human CAL-1 cells Paulo Antas,Mariana D Machado,Fátima Leite-Pinheiro,Daniela Barros,Carlota Ramalhinhoet al. Cellular and Molecular Biology Letters, 2026, Online ahead of print. ⟨10.1186/s11658-025-00841-4⟩ Article dans une revue hal-05477288v1
Immunometabolic reprogramming of macrophages by gut microbiota-derived cadaverine controls colon inflammation Rodrigo de Oliveira Formiga,Qing Li,Yining Zhao,Márcio Augusto Campos Ribeiro,Perle Guarino-Vignonet al. Cell Host & Microbe, 2025, 33 (11), pp.1855-1872.e10. ⟨10.1016/j.chom.2025.09.009⟩ Article dans une revue hal-05311416v1
Sustained Macrophage Reprogramming Is Required for CD8+ T cell–Dependent Long-Term Tumor Eradication Carolina Jardim,Marta Bica,Mariana Reis-Sobreiro,Afonso Teixeira da Mota,Raquel Lopeset al. Cancer Immunology Research, 2025, 13 (8), pp.1207-1225. ⟨10.1158/2326-6066.CIR-24-0797⟩ Article dans une revue hal-05416980v1
Induction of the ISR by AB5 subtilase cytotoxin drives type-I IFN expression in pDCs via STING activation Daniela Barros,Beatriz H Ferreira,Paulina Garcia-Gonzalez,Francesco Carbone,Marine Lukaet al. Proceedings of the National Academy of Sciences of the United States of America, 2025, 122 (21), pp.e2421258122. ⟨10.1073/pnas.2421258122⟩ Article dans une revue hal-05348432v1
Effect of the mitophagy inducer urolithin A on age-related immune decline: a randomized, placebo-controlled trial Dominic Denk,Anurag Singh,Herbert Kasler,Davide D’amico,Julia Reyet al. Nature Aging, 2025, 5 (11), pp.2309-2322. ⟨10.1038/s43587-025-00996-x⟩ Article dans une revue hal-05515256v1
The metabolic profile of circulating plasmacytoid dendritic cells from patients with systemic sclerosis Beatriz Ferreira,Carolina Mazeda,Eduardo Dourado,João Simões,Ana Rita Prataet al. Arthritis Research & Therapy, 2025, 27 (1), pp.35. ⟨10.1186/s13075-025-03500-3⟩ Article dans une revue hal-05348525v1
Single-cell proteomics characterization of bone marrow hematopoiesis with distinct Ras pathway lesions Laila Karra,Anna-Marie Finger,Lauren Shechtman,Milana Krush,Rita Menget al. Blood Advances, 2025, ⟨10.1182/bloodadvances.2024014411.⟩ Article dans une revue hal-05505727v1
Metabolic reprogramming of interleukin-17-producing γδ T cells promotes ACC1-mediated de novo lipogenesis under psoriatic conditions Yu-San Kao,Mario Lauterbach,Aleksandra Lopez Krol,Ute Distler,Gloria Janet Godoyet al. Nature Metabolism, 2025, 7 (5), pp.966 - 984. ⟨10.1038/s42255-025-01276-z⟩ Article dans une revue hal-05417010v1
Uptake of lipids from ascites drives NK cell metabolic dysfunction in ovarian cancer Karen Slattery,Cong-Hui Yao,Eimear Mylod,John Scanlan,Barry Scottet al. Science Immunology, 2025, 10 (107), pp.eadr4795. ⟨10.1126/sciimmunol.adr4795⟩ Article dans une revue hal-05417026v1
Microbial metabolite indole-3-propionic acid drives mitochondrial respiration in CD4+ T cells to confer protection against intestinal inflammation Qing Li,Rodrigo de Oliveira Formiga,Virginie Puchois,Laura Creusot,Ahmad Haidar Ahmadet al. Nature Metabolism, 2025, 7 (12), pp.2510-2530. ⟨10.1038/s42255-025-01396-6⟩ Article dans une revue pasteur-05390470v1
Glucose metabolism controls monocyte homeostasis and migration but has no impact on atherosclerosis development in mice Alexandre Gallerand,Bastien Dolfi,Marion I Stunault,Zakariya Caillot,Alexia Castiglioneet al. Nature Communications, 2024, 15, ⟨10.1038/s41467-024-53267-5⟩ Article dans une revue hal-04780837v1
Defective mitochondria remodelling in B cells leads to an aged immune response Marta Iborra-Pernichi,Jonathan Ruiz García,María Velasco de la Esperanza,Belén S Estrada,Elena R Bovolentaet al. Nature Communications, 2024, 15 (1), pp.2569. ⟨10.1038/s41467-024-46763-1⟩ Article dans une revue hal-04743987v1
Induction of the ISR by AB5 subtilase cytotoxin drives type-I IFN expression in pDCs via STING activation Daniela Barros,Beatriz Ferreira,Paulina Garcia-Gonzalez,Francesco Carbone,Marine Lukaet al. BioRxiv, 2024, ⟨10.1101/2024.10.07.616986⟩ Article dans une revue hal-04793368v1
Lymphotoxin limits Foxp3+ regulatory T cell development from Foxp3lo precursors via IL-4 signaling Alexia Borelli,Jérémy C Santamaria,Cloé Zamit,Cécile Apert,Jessica Chevallieret al. Nature Communications, 2024, 15, pp.6976. ⟨10.1038/s41467-024-51164-5⟩ Article dans une revue hal-04780863v1
Metabolically active neutrophils represent a permissive niche for Mycobacterium tuberculosis J Tucker Andrews,Zijing Zhang,G V R Krishna Prasad,Fischer Huey,Evgeniya V Nazarovaet al. Mucosal Immunology, 2024, 17 (5), pp.825 - 842. ⟨10.1016/j.mucimm.2024.05.007⟩ Article dans une revue hal-04780933v1
VPS34-IN1 inhibits cap-mediated translation and synergizes with STING to drive type-I IFN expression in human plasmacytoid DCs Paulo Antas,Mariana Machado,Fátima Leite-Pinheiro,Daniela Barros,Carlota Ramalhinhoet al. BioRxiv, 2024, ⟨10.1101/2024.06.17.599308⟩ Article dans une revue hal-04793449v1
Immunosenescence and vaccine efficacy revealed by immunometabolic analysis of SARS-CoV-2-specific cells in multiple sclerosis patients Sara de Biasi,Domenico Lo Tartaro,Anita Neroni,Moritz Rau,Nikolaos Paschalidiset al. Nature Communications, 2024, 15, ⟨10.1038/s41467-024-47013-0⟩ Article dans une revue hal-04743975v1
Parallel single-cell metabolic analysis and extracellular vesicle profiling reveal vulnerabilities with prognostic significance in acute myeloid leukemia Dorian Forte,Roberto Maria Pellegrino,Paolo Falvo,Paulina Garcia-Gonzalez,Husam B R Alabedet al. Nature Communications, 2024, 15 (1), pp.10878. ⟨10.1038/s41467-024-55231-9⟩ Article dans une revue hal-05417047v1
Elevated glycolytic metabolism of monocytes limits the generation of HIF1A-driven migratory dendritic cells in tuberculosis Mariano Maio,Joaquina Barros,Marine Joly,Zoï Vahlas,José Luis Marín Francoet al. eLife, 2024, 12 (8), pp.e1011559. ⟨10.7554/eLife.89319⟩ Article dans une revue hal-04738385v1
Dysfunctional subsets of CD39+ T cells, distinct from PD-1+, driven by leukemic extracellular vesicles in myeloid leukemias Julian Swatler,Domenico Lo Tartaro,Rebecca Borella,Marta Brewinska-Olchowik,Annamaria Paoliniet al. Haematologica, 2023, 108 (3), pp.909-916. ⟨10.3324/haematol.2022.281713⟩ Article dans une revue hal-04239656v1
OXPHOS promotes apoptotic resistance and cellular persistence in T &lt;sub&gt;H&lt;/sub&gt; 17 cells in the periphery and tumor microenvironment Hanna S Hong,Nneka E Mbah,Mengrou Shan,Kristen Loesel,Lin Linet al. Science Immunology, 2023, 7, ⟨10.1126/sciimmunol.abm8182⟩ Article dans une revue hal-04062465v1
Light-inducible T cell engagers trigger, tune and shape the activation of primary T cells Morgane Jaeger,Amandine Anastasio,Léa Chamy,Sophie Brustlein,Renaud Vincentelliet al. Proceedings of the National Academy of Sciences of the United States of America, 2023, 120 (39), pp.e2302500120. ⟨10.1073/pnas.2302500120⟩ Article dans une revue hal-03775201v2
Biallelic NFATC1 mutations cause an inborn error of immunity with impaired CD8+ T-cell function and perturbed glycolysis Sevgi Kostel Bal,Sarah Giuliani,Jana Block,Peter Repiscak,Christoph Hafemeisteret al. Blood, 2023, 142 (9), pp.827-845. ⟨10.1182/blood.2022018303⟩ Article dans une revue hal-04309057v1
Immuno-metabolic dendritic cell vaccine signatures associate with overall survival in vaccinated melanoma patients Juraj Adamik,Paul V Munson,Deena M Maurer,Felix J Hartmann,Sean C Bendallet al. Nature Communications, 2023, 14 (1), pp.7211. ⟨10.1038/s41467-023-42881-4⟩ Article dans une revue hal-04534383v1
Immuno-metabolic dendritic cell vaccine signatures associate with overall survival in vaccinated melanoma patients Juraj Adamik,Paul V Munson,Deena M Maurer,Felix J Hartmann,Sean C Bendallet al. Nature Communications, 2023, 14, pp.7211. ⟨10.1038/s41467-023-42881-4⟩ Article dans une revue hal-04780978v1
Holistic Characterization of Tumor Monocyte-to-Macrophage Differentiation Integrates Distinct Immune Phenotypes in Kidney Cancer Adriana Mujal,Alexis Combes,Arjun Rao,Mikhail Binnewies,Bushra Samadet al. Cancer Immunology Research, 2022, 10 (4), pp.403-419. ⟨10.1158/2326-6066.CIR-21-0588⟩ Article dans une revue hal-04027478v1
Unravelling the sex-specific diversity and functions of adrenal gland macrophages Bastien Dolfi,Alexandre Gallerand,Maria Firulyova,Yingzheng Xu,Johanna Merlinet al. Cell Reports, 2022, 39 (11), pp.110949. ⟨10.1016/j.celrep.2022.110949⟩ Article dans une revue hal-03858946v1
An integrated toolbox to profile (macrophage) immunometabolism Sanne G.S. Verberk,Kyra de Goede,Friederike Gorki,Xanthe A.M.H. van Dierendonck,Rafael J Argüelloet al. Cell Reports Methods, 2022, 2 (4), pp.100192. ⟨10.1016/j.crmeth.2022.100192⟩ Article dans une revue hal-03856610v1
An integrated toolbox to profile macrophage immunometabolism Sanne G.S. Verberk,Kyra de Goede,Friederike Gorki,Xanthe A.M.H. van Dierendonck,Rafael J Argüelloet al. Cell Reports Methods, 2022, 2 (4), pp.100192. ⟨10.1016/j.crmeth.2022.100192⟩ Article dans une revue hal-03867132v1
ILC precursors differentiate into metabolically distinct ILC1-like cells during Mycobacterium tuberculosis infection Dan Corral,Alison Charton,Maria Z Krauss,Eve Blanquart,Florence Levillainet al. Cell Reports, 2022, 39 (3), pp.110715. ⟨10.1016/j.celrep.2022.110715⟩ Article dans une revue hal-03951977v1
Discovering dominant tumor immune archetypes in a pan-cancer census Alexis Combes,Bushra Samad,Jessica Tsui,Nayvin Chew,Peter Yanet al. Cell, 2022, 185 (1), pp.184-203.e19. ⟨10.1016/j.cell.2021.12.004⟩ Article dans une revue hal-03549512v1
Plasmatic MMP9 released from tumor-infiltrating neutrophils is predictive for bevacizumab efficacy in glioblastoma patients: an AVAglio ancillary study Carine Jiguet-Jiglaire,Sebastien Boissonneau,Emilie Denicolai,Victoria Hein,Romain Lasseuret al. Acta Neuropathologica Communications, 2022, 10 (1), pp.1. ⟨10.1186/s40478-021-01305-4⟩ Article dans une revue hal-03549379v1
Distinct metabolic states guide maturation of inflammatory and tolerogenic dendritic cells Juraj Adamik,Paul V Munson,Felix J Hartmann,Alexis J Combes,Philippe Pierreet al. Nature Communications, 2022, 13, ⟨10.1038/s41467-022-32849-1⟩ Article dans une revue hal-03817576v1
Transcriptional reprogramming from innate immune functions to a pro-thrombotic signature by monocytes in COVID-19 Allison K Maher,Katie L Burnham,Emma M Jones,Michelle M H Tan,Rocel C Saputilet al. Nature Communications, 2022, 13, ⟨10.1038/s41467-022-35638-y⟩ Article dans une revue hal-03959998v1
Unravelling the sex-specific diversity and functions of adrenal gland macrophages Bastien Dolfi,Alexandre Gallerand,Maria M Firulyova,Yingzheng Xu,Johanna Merlinet al. Cell Reports, 2022, 39, ⟨10.1016/j.celrep.2022.110949⟩ Article dans une revue hal-03794801v1
Distinct metabolic programs established in the thymus control effector functions of γδ T cell subsets in tumor microenvironments Noella Lopes,Claire Mcintyre,Stefania Martin,Mathilde Raverdeau,Nital Sumariaet al. Nature Immunology, 2021, 22 (2), pp.179-192. ⟨10.1038/s41590-020-00848-3⟩ Article dans une revue hal-03121669v1
Proteostasis in dendritic cells is controlled by the PERK signaling axis independently of ATF4 Andreia Mendes,Julien P Gigan,Christian Rodriguez Rodrigues,Sébastien A Choteau,Doriane Sanseauet al. Life Science Alliance, 2021, 4 (2), pp.e202000865. ⟨10.26508/lsa.202000865⟩ Article dans une revue hal-03121710v1
Mitochondrial inhibitors circumvent adaptive resistance to venetoclax and cytarabine combination therapy in acute myeloid leukemia Claudie Bosc,Estelle Saland,Aurélie Bousard,Noémie Gadaud,Marie Sabatieret al. Nature Cancer, 2021, 2 (11), pp.1204-1223. ⟨10.1038/s43018-021-00264-y⟩ Article dans une revue hal-03565962v1
SCENITH: A Flow Cytometry-Based Method to Functionally Profile Energy Metabolism with Single-Cell Resolution Rafael J Argüello 1∞,Rafael Argüello,Alexis J Combes,Remy Char,Julien-Paul Giganet al. Cell Metabolism, 2020, 32 (6), pp.1063-1075.e7. ⟨10.1016/j.cmet.2020.11.007⟩ Article dans une revue hal-03082094v1
At the crossway of ER-stress and proinflammatory responses Marisa Reverendo,Andreia Mendes,Rafael Argüello,Evelina Gatti,Philippe Pierre FEBS Journal, 2019, 286 (2), pp.297-310. ⟨10.1111/febs.14391⟩ Article dans une revue hal-03082823v1
Polymerase III transcription is necessary for T cell priming by dendritic cells Marisa Reverendo,Rafael J Argüello,Christine Polte,Jan Valečka,Voahirana Camossetoet al. Proceedings of the National Academy of Sciences of the United States of America, 2019, ⟨10.1073/pnas.1904396116⟩ Article dans une revue hal-02363598v1
Polymerase III transcription is necessary for T cell priming by dendritic cells Marisa Reverendo,Rafael Argüello,Christine Polte,Jan Valečka,Voahirana Camossetoet al. Proceedings of the National Academy of Sciences of the United States of America, 2019, 116 (45), pp.22721-22729. ⟨10.1073/pnas.1904396116⟩ Article dans une revue hal-03082832v1
At the crossway of ER-stress and proinflammatory responses Marisa Reverendo,Andreia Mendes,Rafael J. Arguello,Evelina Gatti,Philippe Pierre FEBS Journal, 2019, 286 (2, SI), pp.297-310. ⟨10.1111/febs.14391⟩ Article dans une revue hal-02359462v1
SunRiSE – measuring translation elongation at single-cell resolution by means of flow cytometry Rafael J Argüello,Marisa Reverendo,Andreia Mendes,Voahirana Camosseto,Adrian G Torreset al. Journal of Cell Science, 2018, 131 (10), pp.jcs214346. ⟨10.1242/jcs.214346⟩ Article dans une revue hal-01982340v1
BAD-LAMP controls TLR9 trafficking and signalling in human plasmacytoid dendritic cells Alexis Combes,Voahirana Camosseto,Prudence N’guessan,Rafael J Argüello,Julie Mussardet al. Nature Communications, 2017, 8 (1), pp.913. ⟨10.1038/s41467-017-00695-1⟩ Article dans une revue hal-03545468v1
Protein synthesis inhibition and GADD34 control IFN‐β heterogeneous expression in response to dsRNA Alexandre Dalet,Rafael J Argüello,Alexis Combes,Lionel Spinelli,Sebastien Jaegeret al. EMBO Journal, 2017, 36 (6), pp.761 - 782. ⟨10.15252/embj.201695000⟩ Article dans une revue hal-01476255v1
tRNAs: new regularors of immunity? R. J. Arguello,M. Reverendo,S. Terawaki,A. Combes,T. P. Vu-Manhet al. European Journal of Immunology, 2016, 46 (1, SI), pp.787-788 Article dans une revue hal-01438141v1
Regulation of protein synthesis and autophagy in activated dendritic cells: implications for antigen processing and presentation Rafael J. Arguello,Marisa Reverendo,Evelina Gatti,Philippe Pierre Immunological Reviews, 2016, 272 (1, SI), pp.28-38. ⟨10.1111/imr.12427⟩ Article dans une revue istex hal-01438152v1

Communication dans un congrès (3)

Energetic metabolism profiling with single cell resolution Rafael J Argüello 54th Annual meeting of the Society for Leukocyte Biology “Immunometabolism: Fueling the flame of Aging, Cancer and Immunity”, Jun 2021, London, United Kingdom Communication dans un congrès hal-03451766v1
Profiling energetic metabolism and epigenetics by Flow cyometry Rafael J Argüello 4th Edition: Metabolism and Cancer. https://www.metabolism-cancer.com/program/, May 2021, Bordeaux, France Communication dans un congrès hal-03451780v1
IMMUNO-METABOLIC SIGNATURES OF DENDRITIC CELLS ASSOCIATE WITH T-CELL RESPONSES IN MELANOMA PATIENTS Juraj Adamik,Deena Maurer,Paul Munson,Alexis Combes,Philippe Pierreet al. SICT, Nov 2020, Los Angeles, United States. pp.A325 - A325, ⟨10.1136/jitc-2020-sitc2020.0299⟩ Communication dans un congrès hal-03451694v1

Chapitre d'ouvrage (1)

Measuring the Metabolic State of Tissue-Resident Macrophages via SCENITH Andrea Vogel,Paulina García González,Rafael J Argüello Tissue-Resident Macrophages, 2713, Springer US, pp.363-376, 2024, Methods in Molecular Biology, ⟨10.1007/978-1-0716-3437-0_25⟩ Chapitre d'ouvrage hal-04780672v1

Pré-publication, Document de travail (10)

Connecting mitochondrial metabolism and mitotic fidelity to control vulnerability of high grade serous ovarian cancer patients to taxane-based chemotherapy Hadia Moindjie,Morgane Morin,Evanthia Pangou,Diego Chianese,Cynthia Seileret al. 2026 Pré-publication, Document de travail (preprint/prepublication) hal-05462261v1
Microbiota promote enhanced CD39 expression in γδ intraepithelial lymphocytes through the activation of TCR and IL-15 signaling Sara Alonso,Harsimran Kaur,Luo Jia,Mai-Uyen Nguyen,Alyssa Laguertaet al. 2025 Pré-publication, Document de travail hal-05417036v1
Lipid-mediated GPR32 signaling reprograms macrophage metabolism to impair anti-tuberculous immunity Joaquina Barros,Mariano Maio,Martín Manuel Ledesma,María Emilia Boix,Natacha Faivreet al. 2025 Pré-publication, Document de travail hal-05387674v1
“Single-Nuclei Analysis of the Unfolded Protein Response (SNUPR) reveals bortezomib resistance mechanisms in Multiple Myeloma” Julien P Gigan,Paulina Garcia-Gonzalez,Lou Galliot,Alexandre Reynaud,Yoan Ghaffaret al. 2025 Pré-publication, Document de travail hal-05348771v1
Single-Nuclei Analysis of the Unfolded Protein Response (SNUPR): A Novel Method revealing bortezomib resistance mechanisms in Multiple Myeloma Julien Gigan,Paulina Garcia-Gonzalez,Lou Galliot,Alexandre Reynaud,Yoan Ghaffaret al. 2024 Pré-publication, Document de travail (preprint/prepublication) hal-04791295v1
Metabolically Primed Multipotent Hematopoietic Progenitors Fuel Innate Immunity Jason Cosgrove,Anne-Marie Lyne,Ildefonso Rodriguez,Vincent Cabeli,Cecile Conradet al. 2023 Pré-publication, Document de travail hal-04286084v1
Metabolic regulation of ILC2 differentiation into ILC1-like cells during Mycobacterium tuberculosis infection Dan Corral,Alison Charton,Maria Z Krauss,Eve Blanquart,Florence Levillainet al. 2021 Pré-publication, Document de travail hal-03451521v1
Holistic Characterization of Tumor Monocyte-to-Macrophage Differentiation Integrates Distinct Immune Phenotypes in Kidney Cancer Adriana M Mujal,Alexis J Combes,Arjun R Rao,Mikhail Binnewies,Bushra Samadet al. 2021 Pré-publication, Document de travail hal-03451508v3
A Pan-Cancer Census of Dominant Tumor Immune Archetypes Rafael J Argüello,Alexis Combes,Bushra Samad,Jessica Tsui,Nayvin Chewet al. 2021 Pré-publication, Document de travail hal-03407890v1
A toolbox to profile immunometabolism tested in macrophages Sanne G S Verberk,Kyra E de Goede,Friederike S Gorki,Xanthe a M H van Dierendonck,Rafael J Argüelloet al. 2021 Pré-publication, Document de travail hal-03451467v1