Regis BOBE

Publications

Article dans une revue (16)

SERCA3, ubiquitous but specific calcium pumps? Maëliss Toth,Shaymaa Alhabib,Boris Manoury,Régis Bobe,Véronique Leblais Cell Calcium, 2025, 132, pp.103079. ⟨10.1016/j.ceca.2025.103079⟩ Article dans une revue hal-05304354v1
Piezo1 gain of function induces a platelet preactivation state Christilla Bachelot-Loza,Aurore Marchelli,Laurie Ruch,Divina El Hamaoui,Julien Demagnyet al. Journal of Thrombosis and Haemostasis, 2025, ⟨10.1016/j.jtha.2025.11.028⟩ Article dans une revue hal-05441209v1
The Protein Kinase A Inhibitor KT5720 Prevents Endothelial Dysfunctions Induced by High-Dose Irradiation François-Xavier Boittin,Nathalie Guitard,Maeliss Toth,Diane Riccobono,Hélène Théryet al. International Journal of Molecular Sciences, 2024, 25 (4), pp.2269. ⟨10.3390/ijms25042269⟩ Article dans une revue hal-05304377v1
Two-pore channels (TPCs) acts as a hub for excitation-contraction coupling, metabolism and cardiac hypertrophy signalling Antoine de Zélicourt,Abdallah Fayssoil,Arnaud Mansart,Faouzi Zarrouki,Ahmed Karouiet al. Cell Calcium, 2024, 117, pp.102839. ⟨10.1016/j.ceca.2023.102839⟩ Article dans une revue hal-04409238v1
Niemann-Pick C1 protein regulates platelet membrane–associated calcium ion signaling in thrombo-occlusive diseases in mice Mailin-Christin Manke,Anna Roslan,Britta Walker,Patrick Münzer,Ferdinand Kollotzeket al. Journal of Thrombosis and Haemostasis, 2023, 21 (7), pp.1957-1966. ⟨10.1016/j.jtha.2023.03.038⟩ Article dans une revue hal-04453749v1
ADP receptor P2Y12 is the capstone of the cross-talk between Ca 2+ mobilization pathways dependent on ATPases SERCA3 and SERCA2b in platelet Miao Feng,Béatrice Hechler,Frédéric Adam,Christian Gachet,Anita Ecklyet al. Research and Practice in Thrombosis and Haemostasis, In press Article dans une revue (data paper) hal-03930689v1
The immunosuppressant drug Cyclosporin A aggravates irradiation effects in endothelial cells François-Xavier Boittin,Kathia Beddek,Hélène Thery,Jérome Pateux,Guillaume Cosleret al. Biochemical and Biophysical Research Communications, 2022, 602, pp.127-134. ⟨10.1016/j.bbrc.2022.02.096⟩ Article dans une revue hal-04453742v1
Endoglin Is an Endothelial Housekeeper against Inflammation: Insight in ECFC-Related Permeability through LIMK/Cofilin Pathway Elisa Rossi,Alexandre Kauskot,François Saller,Elisa Frezza,Sonia Poirault-Chassacet al. International Journal of Molecular Sciences, 2021, 22 (16), pp.8837. ⟨10.3390/ijms22168837⟩ Article dans une revue hal-03388849v1
SERCA3 calcium pump: discovery of a new calcium signalling pathway that triggers platelet activation Miao Feng,Jean‐philippe Rosa,Regis Bobe Revue Francophone d'Hémostase et Thrombose, 2021, 3 (1), pp.41-6 Article dans une revue hal-04453801v1
TRPV4 channel activation induces the transition of venous and arterial endothelial cells toward a pro‐inflammatory phenotype Kathia Beddek,Florent Raffin,Delphine Borgel,François Saller,Diane Riccobonoet al. Physiological Reports, 2021, 9 (3), ⟨10.14814/phy2.14613⟩ Article dans une revue hal-04453732v1
NAADP/SERCA3-dependent Ca2+ stores pathway specifically controls early autocrine ADP secretion potentiating platelet activation. Miao Feng,Ziane Elaïb,Delphine Borgel,Cécile Denis,Frédéric Adamet al. Circulation Research, 2020, 127 (7), pp.e166-e183. ⟨10.1161/CIRCRESAHA.119.316090⟩ Article dans une revue inserm-02948394v1
Platelet Functions are Decreased in Obesity and Restored after Weight Loss: Evidence for a Role of the SERCA3-Dependent ADP Secretion Pathway Ziane Elaïb,Jose Lopez,Muriel Coupaye,Kevin Zuber,Yann Beckeret al. Thrombosis and Haemostasis, 2019, 119 (03), pp.384-396. ⟨10.1055/s-0038-1677033⟩ Article dans une revue hal-04453727v1
Filamin A Modulates Store-Operated Ca 2+ Entry by Regulating STIM1 (Stromal Interaction Molecule 1)–Orai1 Association in Human Platelets Jose Lopez,Letizia Albarrán,Isaac Jardín,Jose Sanchez-Collado,Pedro Redondoet al. Arteriosclerosis, Thrombosis, and Vascular Biology, 2018, 38 (2), pp.386-397. ⟨10.1161/ATVBAHA.117.310139⟩ Article dans une revue hal-04457054v1
Dominant negative Ras (DN Ras) attenuates pathological ventricular remodeling in pressure overload cardiac hypertrophy Manuel Ramos-Kuri,Kleopatra Rapti,Hind Mehel,Shihong Zhang,Perundurai S Dhandapanyet al. Biochimica et Biophysica Acta - Molecular Cell Research, 2015, 1853 (11), pp.2870-2884. ⟨10.1016/j.bbamcr.2015.08.006⟩ Article dans une revue hal-02610567v1
Expression of sarco (endo) plasmic reticulum calcium ATPase (SERCA) system in normal mouse cardiovascular tissues, heart failure and atherosclerosis Larissa Lipskaia,Zela Keuylian,Karl Blirando,Nathalie Mougenot,Adeline Jacquetet al. Biochimica et Biophysica Acta - Molecular Cell Research, 2014, 1843 (11), pp.2705-2718. ⟨10.1016/j.bbamcr.2014.08.002⟩ Article dans une revue hal-01545429v1
Crucial Role for Endoplasmic Reticulum Stress During Megakaryocyte Maturation Jose Lopez,Alberta Palazzo,Chiraz Chaabane,Letizia Albarran,Evelyne Polidanoet al. Arteriosclerosis, Thrombosis, and Vascular Biology, 2013, 33 (12), pp.2750-2758. ⟨10.1161/ATVBAHA.113.302184⟩ Article dans une revue hal-04472255v1

Poster de conférence (8)

Le récepteur PAR4 initie la voie SERCA3/NAADP qui potentialise l'activation des plaquettes en réponse à la thrombine. Miao Feng,Frédéric Adam,Alexandre Kauskot,Cécile Denis,Marijke Bryckaertet al. Congrès Francais d'Hémostase, May 2023, Saint malo, France Poster de conférence hal-04455436v1
The immunosuppressant drug Cyclosporin A aggravates irradiation effects in endothelial cells François-Xavier Boittin,Kathia Beddek,Hélène Thery,Jérome Pateux,Guillaume Cosleret al. CRBNE Research & Innovation conference, May 2022, Lille, France Poster de conférence hal-04455715v1
NAADP/SERCA3-Dependent Ca2+ Stores Pathway Specifically Controls Early Autocrine ADP Secretion Potentiating Platelet Activation Miao Feng,Ziane Elaib,Delphine Borgel,Cécile Denis,Frederic Adamet al. Virtual Congress of the International Society on Thrombosis and Haemostasis, Jul 2020, Milan (Virtual), Italy. Res. Pract. Thromb. Haemost, 4 (Suppl. 1), pp.Abstract PB1745, 2020 Poster de conférence hal-04501065v1
Ca2+ release from Sarco/Endoplamic Reticulum Ca2+-ATPase 3 (SERCA3) controlled stores is involved in endothelial permeability and inflammatory response. Kathia Beddek,Frédéric Adam,Francois Saller,Delphine Borgel,Regis Bobe ISTH 2020, Jul 2020, Virtual conference, France Poster de conférence hal-04455301v1
NAADP/SERCA3-dependent Ca2+ stores pathway specifically controls early autocrine ADP secretion potentiating platelet activation. Miao Feng,Ziane Elaib,Delphine Borgel,Cécile V. Denis,Frédéric Adamet al. ISTH 2020, Jul 2020, Virtual congress, France Poster de conférence hal-04455286v1
ROLE OF THE SERCA3/NAADP SIGNALING IN THE CARDIOVASCULAR SYSTEM Miao Feng,Antoine de Zélicourt,Justine Page,José‐manuel Cancela,Sabine de La Porteet al. Huitième colloque du LabEx Lermit, Nov 2019, Gif-sur-Yvette, France Poster de conférence hal-04455220v1
ROLE OF THE SERCA3/NAADP SIGNALING IN THE CARDIOVASCULAR SYSTEM Miao Feng,Antoine de Zélicourt,Justine Page,José-Manuel Cancela,Sabine de La Porteet al. Huitième colloque du LabEx Lermit, Nov 2019, Gif-sur-Yvette, France Poster de conférence hal-04519880v1
Specific mobilization of SERCA3-dependent Ca2+ stores by NAADP regulates platelet activity through ADP secretion. Ziane Elaib,Miao Feng,Frédéric Adam,Marijke Bryckaert,Jean‐philippe Rosaet al. 15th International Meeting of the European Calcium Society, Sep 2018, Hambourg (Germany), Germany Poster de conférence hal-04455185v1

Communication dans un congrès (4)

Réserves de calcium et fonctions plaquettaires Regis Bobe 9eme rencontre du CFPM, May 2022, Bordeaux (France), France Communication dans un congrès hal-04455403v1
La diminution de l’activité des pompes à calcium SERCA3 permet la réduction de la réponse inflammatoire. Kathia Beddek,Frédéric Adam,Francois Saller,Delphine Borgel,Regis Bobe 40eme congres de la SFH 2020, Sep 2020, Paris, France Communication dans un congrès hal-04455333v1
L’activation des canaux TRPV4 induit la transition des cellules endothéliales veineuses ou artérielles vers un phénotype pro-inflammatoire. Kathia Beddek,Florent Raffin,Francois Saller,Delphine Borgel,Diane Riccobonoet al. 40eme congres de la SFH, Sep 2020, Paris, France Communication dans un congrès hal-04455362v1
L'ADP sécrétée par la voie de signalisation calcique plaquettaire NAADP/SERCA3 active spécifiquement le récepteur purinergique P2Y12 et pas P2Y1 Miao Feng,Cécile Denis,Regis Bobe,Jean‐philippe Rosa 8ème rencontre Club français des plaquettes et des mégacayocytes, Nov 2020, plateforme zoom, France Communication dans un congrès hal-04455261v1