Reine Nehmé

Identifiants chercheurs

IdHAL :

reine-nehme

ORCID :

0000-0002-5288-7702

IdRef :

145416208

Publications

Article dans une revue (51)

Microscale Thermophoresis for Thermodynamic Analysis: A Proof-of-Concept Study on LIMK Inhibitors Solweig Chartier,Bérengère Claude,Rouba Nasreddine,Pierre Soule,Alexandra Launayet al. Journal of Molecular Biology, 2026, 438 (5), pp.169621. ⟨10.1016/j.jmb.2025.169621⟩ Article dans une revue (article de synthèse) hal-05517956v1
LIM kinase/inhibitor binding study in cell lysates using microscale thermophoresis in the red spectrum Solweig Chartier,Mélanie Rapeto,Rouba Nasreddine,Elodie Villalonga-Rosso,Bérengère Claudeet al. Analytica Chimica Acta, 2026, 1382, pp.344837. ⟨10.1016/j.aca.2025.344837⟩ Article dans une revue hal-05347896v1
Using CE to confirm the activity of fluorescent miRFP670-LIMK1 protein produced for MST assays directly in cell lysate Solweig Chartier,Bérengère Claude,Rouba Nasreddine,Alexandra Launay,Marion Martinset al. Analytica Chimica Acta, 2025, 1360, pp.344145. ⟨10.1016/j.aca.2025.344145⟩ Article dans une revue hal-05304644v1
The antimicrobial activity of ETD151 defensin is dictated by the presence of glycosphingolipids in the targeted organisms Ons Kharrat,Yoshiki Yamaryo-Botté,Rouba Nasreddine,Sébastien Voisin,Thomas Aumeret al. Proceedings of the National Academy of Sciences of the United States of America, 2025, 122 (7), pp.e2415524122. ⟨10.1073/pnas.2415524122⟩ Article dans une revue hal-05304638v1
Molecular recognition of fungal methylated glucosylceramides by ETD151 defensin Ons Kharrat,Françoise Paquet,Rouba Nasreddine,Jean-Baptiste Madinier,Reine Nehméet al. Journal of Biological Chemistry, 2025, 301 (9), pp.110587. ⟨10.1016/j.jbc.2025.110587⟩ Article dans une revue hal-05250295v1
Impacts of Tween-20, Glycerol, and Trehalose on Hyaluronidase Activity: Insights from Microscale Thermophoresis and Capillary Electrophoresis Rouba Nasreddine,Josipa Cecić Vidoš,Alexandra Launay,Reine Nehmé Molecules, 2025, 30 (19), pp.4008. ⟨10.3390/molecules30194008⟩ Article dans une revue hal-05304634v1
A novel green reducing agent for the synthesis of chromium oxide nanoparticles (Cr2O3 NPs) based on saffron by-products: Characterization and antioxidant activity Zineb Khadfy,Rachid Mamouni,S.M. Jadouali,Hajar Atifi,Nabil Saffajet al. Materials Science and Engineering: B, 2024, 305, pp.117415. ⟨10.1016/j.mseb.2024.117415⟩ Article dans une revue hal-04758110v1
Glycolipid and Lipopeptide Biosurfactants: Structural Classes and Characterization—Rhamnolipids as a Model Nadin Darwiche,Christelle Dufresne,Agnès Chartier,Bérengère Claude,Cyril Colaset al. Critical Reviews in Analytical Chemistry, 2024, pp.1-21. ⟨10.1080/10408347.2024.2441428⟩ Article dans une revue hal-05304648v1
A novel natural reducing agent for the preparation of cerium oxide nanoparticles based on the saffron by-product: Characterization, antioxidant and antibacterial activity for nutritional applications Zineb Khadfy,Rachid Mamouni,Si Mohamed Jadouali,Hajar Atifi,Nabil Saffajet al. Nano-Structures & Nano-Objects, 2024, 40, pp.101381. ⟨10.1016/j.nanoso.2024.101381⟩ Article dans une revue hal-04744157v1
Nutraceutical and cosmetic applications of bioactive compounds of Saffron (Crocus Sativus L.) stigmas and its by-products Zineb Khadfy,Hajar Atifi,Rachid Mamouni,Si Mohamed Jadouali,Agnes Chartieret al. South African Journal of Botany, 2023, 163, pp.250-261. ⟨10.1016/j.sajb.2023.10.058⟩ Article dans une revue hal-04758127v1
Nutraceutical Capacities of Extracts from the Invasive Plants Ambrosia Artemisiifolia and Solidago Canadensis Vanille Quinty,Rouba Nasreddine,Cyril Colas,Alexandra Launay,Reine Nehméet al. SSRN Electronic Journal, 2023, ⟨10.2139/ssrn.4447346⟩ Article dans une revue hal-04758340v1
Capillary electrophoresis for enzyme-based studies: Applications to lipases and kinases Ghassan Al Hamoui Dit Banni,Reine Nehmé Journal of Chromatography A, 2022, 1661, pp.462687. ⟨10.1016/j.chroma.2021.462687⟩ Article dans une revue hal-03706495v1
Biosurfactant-Producing Mucor Strains: Selection, Screening, and Chemical Characterization Mélanie Chotard,Jérôme Mounier,Raissa Meye,Carole Padel,Bérengère Claudeet al. Advances in Applied Microbiology, 2022, 2 (1), pp.248-259. ⟨10.3390/applmicrobiol2010018⟩ Article dans une revue hal-04758143v1
The myrosinase-glucosinolate system to generate neoglycoproteins: A case study targeting mannose binding lectins Giuliano Cutolo,Blanka Didak,Josip Tomas,Benoit Roubinet,Pierre Lafiteet al. Carbohydrate Research, 2022, 516, pp.108562. ⟨10.1016/j.carres.2022.108562⟩ Article dans une revue hal-04645367v1
Screening for pancreatic lipase natural modulators by capillary electrophoresis hyphenated to spectrophotometric and conductometric dual detection Ghassan Al Hamoui Dit Banni,Rouba Nasreddine,Syntia Fayad,Phu Cao-Ngoc,Jean-Christophe Rossiet al. Analyst, 2021, 146 (4), pp.1386-1401. ⟨10.1039/d0an02234a⟩ Article dans une revue hal-03835824v1
Investigation of lipase-ligand interactions in porcine pancreatic extracts by microscale thermophoresis Ghassan Al Hamoui Dit Banni,Rouba Nasreddine,Syntia Fayad,Cyril Colas,Axel Marchalet al. Analytical and Bioanalytical Chemistry, 2021, 413 (14), pp.3667-3681. ⟨10.1007/s00216-021-03314-7⟩ Article dans une revue hal-03307692v1
Kinetic theory of hyaluronan cleavage by bovine testicular hyaluronidase in standard and crowded environments Reine Nehmé,Rouba Nasreddine,Lucija Orlic,Chrystel Lopin-Bon,Josef Hamaceket al. Biochimica et Biophysica Acta (BBA) - General Subjects, 2021, 1865 (3), pp.129837. ⟨10.1016/j.bbagen.2020.129837⟩ Article dans une revue hal-03481898v1
Design, Synthesis and SAR in 2,4,7-Trisubstituted Pyrido[3,2-d]Pyrimidine Series as Novel PI3K/mTOR Inhibitors Frédéric Buron,Nuno Rodrigues,Thibault Saurat,Marie-Aude Hiebel,Stéphane Bourget al. Molecules, 2021, 26 (17), pp.5349. ⟨10.3390/molecules26175349⟩ Article dans une revue hal-03348966v1
Microscale thermophoresis for studying protein-small molecule affinity: Application to hyaluronidase Rouba Nasreddine,Reine Nehmé Microchemical Journal, 2021, 170, pp.106763. ⟨10.1016/j.microc.2021.106763⟩ Article dans une revue hal-04758194v1
Reproducibility and accuracy of microscale thermophoresis in the NanoTemper Monolith: a multi laboratory benchmark study Blanca López-Méndez,Bruno Baron,Chad Brautigam,Thomas Jowitt,Stefan Knaueret al. European Biophysics Journal, 2021, 50 (3-4), pp.411-427. ⟨10.1007/s00249-021-01532-6⟩ Article dans une revue hal-03481822v1
Polyethylene glycol crowding effect on hyaluronidase activity monitored by capillary electrophoresis Rouba Nasreddine,Lucija Orlic,Ghassan Al Hamoui Dit Banni,Syntia Fayad,Axel Marchalet al. Analytical and Bioanalytical Chemistry, 2020, 412 (17), pp.4195-4207. ⟨10.1007/s00216-020-02659-9⟩ Article dans une revue hal-02939523v1
Capillary Electrophoresis-Mass Spectrometry at Trial by Metabo-Ring: Effective Electrophoretic Mobility for Reproducible and Robust Compound Annotation Nicolas Drouin,Marlien van Mever,Wei Zhang,Elena Tobolkina,Sabrina Ferreet al. Analytical Chemistry, 2020, 92 (20), pp.14103-14112. ⟨10.1021/acs.analchem.0c03129⟩ Article dans une revue hal-04303264v1
Water-Based Extraction of Bioactive Principles from Blackcurrant Leaves and Chrysanthellum americanum: A Comparative Study Phu Cao-Ngoc,Laurent Leclercq,Jean-Christophe Rossi,Jasmine Hertzog,Anne-Sylvie Fabiano-Tixieret al. Foods, 2020, 9 (10), pp.1478. ⟨10.3390/foods9101478⟩ Article dans une revue hal-03019649v1
Effect of modified di- and trisaccharides on hyaluronidase activity assessed by capillary electrophoresis-based enzymatic assay Syntia Fayad,Benjamin Ayela,Coralie Chat,Philippe Morin,Chrystel Lopin-Bonet al. Carbohydrate Research, 2019, 475, pp.56 - 64. ⟨10.1016/j.carres.2019.02.006⟩ Article dans une revue hal-03486681v1
Diverted Natural Lossen-type Rearrangement for Bioconjugation through in Situ Myrosinase-Triggered Isothiocyanate Synthesis Jean Wilfried Fredy,Giuliano Cutolo,Benjamin Poret,Reine Nehmé,Marie Hubert-Rouxet al. Bioconjugate Chemistry, 2019, 30 (5), pp.1385-1394. ⟨10.1021/acs.bioconjchem.9b00153⟩ Article dans une revue hal-04758207v1
Monitoring of successive phosphorylations of thymidine using free and immobilized human nucleoside/nucleotide kinases by Flow Injection Analysis with High-Resolution Mass Spectrometry Justine Ferey,David da Silva,Cyril Colas,Reine Nehmé,Pierre Lafiteet al. Analytica Chimica Acta, 2019, 1049, pp.115-122. ⟨10.1016/j.aca.2018.10.032⟩ Article dans une revue hal-02090335v1
Capillary electrophoresis with dual detection UV/C4D for monitoring myrosinase-mediated hydrolysis of thiol glucosinolate designed for gold nanoparticle conjugation Bérengère Claude,Giuliano Cutolo,Amal Farhat,Irina Zarafu,Petre Ionitaet al. Analytica Chimica Acta, 2019, 1085, pp.117 - 125. ⟨10.1016/j.aca.2019.07.043⟩ Article dans une revue hal-03487875v1
Preliminary recovery study of a commercial molecularly imprinted polymer for the extraction of glyphosate and AMPA in different environmental waters using MS Bérengère Claude,Catherine Berho,Sami Bayoudh,Laurence Amalric,Emeline Coisyet al. Environmental Science and Pollution Research, 2017, 24 (13), pp.12293-12300. ⟨10.1007/s11356-017-8844-5⟩ Article dans une revue hal-01849658v1
Hyaluronidase reaction kinetics evaluated by capillary electrophoresis with UV and high-resolution mass spectrometry (HRMS) detection Syntia Fayad,Reine Nehmé,Monika Langmajerová,Benjamin Ayela,Cyril Colaset al. Analytica Chimica Acta, 2017, 951, pp.140-150. ⟨10.1016/j.aca.2016.11.036⟩ Article dans une revue istex hal-04270197v1
Microalgae amino acid extraction and analysis at nanomolar level using electroporation and capillary electrophoresis with laser-induced fluorescence detection Reine Nehmé,Carla Atieh,Syntia Fayad,Bérengère Claude,Agnès Chartieret al. Journal of Separation Science, 2017, 40 (2), pp.558-566. ⟨10.1002/jssc.201601005⟩ Article dans une revue hal-01618682v1
Use of chromatographic and electrophoretic tools for assaying elastase, collagenase, hyaluronidase, and tyrosinase activity Syntia Fayad,Philippe Morin,Reine Nehmé Journal of Chromatography A, 2017, 1529, pp.1-28. ⟨10.1016/j.chroma.2017.11.003⟩ Article dans une revue hal-04645321v1
Macroalga Padina pavonica water extracts obtained by pressurized liquid extraction and microwave-assisted extraction inhibit hyaluronidase activity as shown by capillary electrophoresis Syntia Fayad,Reine Nehmé,Mona Tannoury,Eric Lesellier,Chantal Pichonet al. Journal of Chromatography A, 2017, 1497, pp.19-27. ⟨10.1016/j.chroma.2017.03.033⟩ Article dans une revue istex hal-01618229v1
Human neutrophil elastase inhibition studied by capillary electrophoresis with laser induced fluorescence detection and microscale thermophoresis Fayad Syntia,Reine Nehmé,Bérengère Claude,Philippe Morin Journal of Chromatography A, 2016, 1431, pp.215-223. ⟨10.1016/j.chroma.2015.12.079⟩ Article dans une revue istex hal-04758246v1
Advances in capillary electrophoresis for miniaturizing assays on kinase enzymes for drug discovery Reine Nehmé,Philippe Morin Electrophoresis, 2015, 36 (21-22), pp.2768-2797. ⟨10.1002/elps.201500239⟩ Article dans une revue istex hal-04758248v1
Assaying human neutrophil elastase activity by capillary zone electrophoresis combined with laser-induced fluorescence Syntia Fayad,Reine Nehmé,Pierre Lafite,Philippe Morin Journal of Chromatography A, 2015, 1419, pp.116-124. ⟨10.1016/j.chroma.2015.09.084⟩ Article dans une revue istex hal-03478319v1
New methods based on capillary electrophoresis for in vitro evaluation of protein tau phosphorylation by glycogen synthase kinase 3-β Hala Nehmé,Sandrine Chantepie,Justine Defert,Philippe Morin,Dulce Papy-Garciaet al. Analytical and Bioanalytical Chemistry, 2015, 407 (10), pp.2821-2828. ⟨10.1007/s00216-015-8495-7⟩ Article dans une revue hal-04758253v1
Coated capillaries with highly charged polyelectrolytes and carbonnanotubes co-aggregated with sodium dodecyl sulphate for theanalysis of sulfonylureas by capillary electrophoresis Racha El Debs,Bérengère Claude,Anne Togola,Solène Motteau,Reine Nehméet al. Journal of Chromatography A, 2014, 1367, pp.161-166. ⟨10.1016/j.chroma.2014.09.047⟩ Article dans une revue istex hal-01086599v1
Contactless conductivity detection for screening myrosinase substrates by capillary electrophoresis Reine Nehmé,Hala Nehmé,Grégory Roux,Deimante Cerniauskaite,Philippe Morinet al. Analytica Chimica Acta, 2014, 807, pp.153-158. ⟨10.1016/j.aca.2013.11.012⟩ Article dans une revue istex hal-04758270v1
New in-capillary electrophoretic kinase assays to evaluate inhibitors of the PI3k/Akt/mTOR signaling pathway Reine Nehmé,Hala Nehmé,Thibault Saurat,Marie-Ludivine De-Tauzia,Frédéric Buronet al. Analytical and Bioanalytical Chemistry, 2014, 406 (15), pp.3743-3754. ⟨10.1007/s00216-014-7790-z⟩ Article dans une revue hal-01180770v1
Capillary electrophoresis as a novel technique for screening natural flavonoids as kinase inhibitors Reine Nehmé,Hala Nehmé,Grégory Roux,Emilie Destandau,Bérengère Claudeet al. Journal of Chromatography A, 2013, 1318, pp.257-264. ⟨10.1016/j.chroma.2013.10.024⟩ Article dans une revue istex hal-04758300v1
Human protein kinase inhibitor screening by capillary electrophoresis using transverse diffusion of laminar flow profiles for reactant mixing Hala Nehmé,Reine Nehmé,Pierre Lafite,Sylvain Routier,Philippe Morin Journal of Chromatography A, 2013, 1314, pp.298-305. ⟨10.1016/j.chroma.2013.08.046⟩ Article dans une revue istex hal-04440284v1
In-capillary reactant mixing for monitoring glycerol kinase kinetics by CE Hala Nehmé,Reine Nehmé,Pierre Lafite,Sylvain Routier,Philippe Morin Journal of Separation Science, 2013, 36 (13), pp.2151-2157. ⟨10.1002/jssc.201300063⟩ Article dans une revue istex hal-03478330v1
Electrophoretically mediated microanalysis for in-capillaryelectrical cell lysis and fast enzyme quantification by capillary electrophoresis Hala Nehmé,Reine Nehmé,Pierre Lafite,Eric Duverger,Sylvain Routieret al. Analytical and Bioanalytical Chemistry, 2013, 405 (28), pp.9159-9167. ⟨10.1007/s00216-013-7332-0⟩ Article dans une revue istex hal-03478329v1
New development in in-capillary electrophoresis techniques for kinetic and inhibition study of enzymes Hala Nehme,Reine Nehme,Pierre Lafite,Sylvain Routier,Philippe Morin Analytica Chimica Acta, 2012, 722, pp.127-135. ⟨10.1016/j.aca.2012.02.003⟩ Article dans une revue istex hal-04440273v1
Analysis of urinary neurotransmitters by capillary electrophoresis: Sensitivity enhancement using field-amplified sample injection and molecular imprinted polymer solid phase extraction Bérengère Claude,Reine Nehmé,Philippe Morin Analytica Chimica Acta, 2011, 699 (2), pp.242-248. ⟨10.1016/j.aca.2011.05.014⟩ Article dans une revue istex hal-04758320v1
Stability of capillaries coated with highly charged polyelectrolyte monolayers and multilayers under various analytical conditions - Applications to protein analysis Reine Nehmé,Catherine Perrin,Hervé Cottet,Marie-Dominique Blanchin,Huguette Fabre Journal of Chromatography A, 2011, 1218 (22), pp.3537-3544. ⟨10.1016/j.chroma.2011.03.040⟩ Article dans une revue istex hal-00772504v1
Capillary electrophoresis procedure for the simultaneous analysis and stoichiometry determination of a drug and its counter-ion by using dual-opposite end injection and contactless conductivity detection: Application to labetalol hydrochloride Reine Nehmé,Adrien Lascaux,Raphaël Delépée,Bérengère Claude,Philippe Morin Analytica Chimica Acta, 2010, 663 (2), pp.190-197. ⟨10.1016/j.aca.2010.01.032⟩ Article dans une revue istex hal-04758324v1
Capillary electrophoresis procedure for the simultaneous analysis and stoichiometry determination of a drug and its counter-ion by using dual-opposite end injection and contactless conductivity detection: Application to labetalol hydrochloride Reine Nehmé,Adrien Lascaux,Raphaël Delépée,Bérengère Claude,Philippe Morin Analytica Chimica Acta, 2010, 663 (2), pp.190-197. ⟨10.1016/j.aca.2010.01.032⟩ Article dans une revue istex hal-03593446v1
Influence of polyelectrolyte capillary coating conditions on protein analysis in CE Reine Nehmé,Catherine Perrin,Hervé Cottet,Marie‐dominique Blanchin,Huguette Fabre Electrophoresis, 2009, 30 (11), pp.1888-1898. ⟨10.1002/elps.200800688⟩ Article dans une revue istex hal-04758329v1
Use of coated capillaries for the electrophoretic separation of stereoisomers of a growth hormone secretagogue Jean-Alain Fehrentz,Reine Nehmé,Catherine Perrin,Vincent Guerlavais,Hervé Cottetet al. Electrophoresis, 2009, 30 (21), pp.3772-3779. ⟨10.1002/elps.200900093⟩ Article dans une revue istex hal-00485769v1
Influence of polyelectrolyte coating conditions on capillary coating stability and separation efficiency in capillary electrophoresis Reine Nehmé,Catherine Perrin,Hervé Cottet,Marie Blanchin,Huguette Fabre Electrophoresis, 2008, 29 (14), pp.3013-3023. ⟨10.1002/elps.200700886⟩ Article dans une revue istex hal-04758333v1

Communication dans un congrès (3)

Unveiling the dynamics of enzymatic activity in crowded environments: insights from hyaluronidase kinetics and interactions in extracellular matrix mimics Zahia Bouchelaghem,Rouba Nasreddine,Bérengère Claude,Claudia Bich,Josef Hamaceket al. 34th International Symposium on Pharmaceutical and Biomedical Analysis, Sep 2024, Geneva, Switzerland Communication dans un congrès hal-04851046v1
Toward Understanding of the Extracellular Matrix Remodeling: Enzymatic Kinetics in Synthetic Crowded Mimics Josef Hamacek,Josipa Cecic Vidos,Anand Yethiraj,Francesco Piazza,Reine Nehme Molecular Crowding Workshop, Jul 2022, Grenoble, France Communication dans un congrès hal-04585990v1
Mécanism of hyaluronidase inhibition in model artificial media and in the extracellular matrix Josipa Cecic Vidos,Reine Nehmé,Josef Hamacek RTR MOTIVHEALHT MEETING, Jun 2021, Tours, France Communication dans un congrès hal-03602272v1

Chapitre d'ouvrage (1)

Highly Charged Polyelectrolyte Coatings to Prevent Adsorption During Protein and Peptide Analysis in Capillary Electrophoresis Reine Nehmé,Catherine Perrin Capillary Electrophoresis of Biomolecules, 984, Humana Press, pp.191-206, 2013, Methods in Molecular Biology, ⟨10.1007/978-1-62703-296-4_14⟩ Chapitre d'ouvrage hal-04758293v1