Renaud Poincloux

Publications

Article dans une revue (45)

Moesin controls cell–cell fusion and osteoclast function Ophélie Dufrançais,Marianna Plozza,Marie Juzans,Arnaud Métais,Sarah C Monardet al. Journal of Cell Biology, 2026, 224 (11), ⟨10.1083/jcb.202409169⟩ Article dans une revue hal-05514483v1
Megakaryocytes assemble a three-dimensional cage of extracellular matrix that controls their maturation and anchoring to the vascular niche Claire Masson,Cyril Scandola,Jean-Yves Rinckel,Fabienne Proamer,Emily Janus-Bellet al. eLife, 2025, ⟨10.7554/eLife.104963.3⟩ Article dans une revue pasteur-04721499v2
Capsule-mediated O-antigen masking protects hypervirulent Klebsiella pneumoniae from neutrophil killing Karin Santoni,Joshua L.C Wong,Renaud Poincloux,Etienne Meunier,Gad Frankel BioRxiv, 2025, ⟨10.1101/2025.02.26.640295⟩ Article dans une revue hal-05018837v1
Myosins 1e/f at the podosome base regulate podosome dynamics and promote macrophage migration Pasquale Cervero,Sarah R Barger,Perrine Verdys,Robert Herzog,Tyler Paulet al. European Journal of Cell Biology, 2025, 104 (4), pp.151514. ⟨10.1016/j.ejcb.2025.151514⟩ Article dans une revue hal-05460353v1
Focal adhesions contain three specialized actin nanoscale layers Reena Kumari,Katharina Ven,Megan Chastney,Shrikant Kokate,Johan Peränenet al. Nature Communications, 2024, 15 (1), pp.2547. ⟨10.1038/s41467-024-46868-7⟩ Article dans une revue hal-04639883v1
Ezrin, radixin, and moesin are dispensable for macrophage migration and cellular cortex mechanics Perrine Verdys,Javier Rey Barroso,Adeline Girel,Joseph Vermeil,Martin Bergertet al. EMBO Journal, 2024, 43 (21), pp.4822-4845. ⟨10.1038/s44318-024-00173-7⟩ Article dans une revue hal-04735160v1
Lymphocyte migration and retention properties affected by ibrutibnib in chronic lymphocytic leukemia Javier Rey-Barroso,Alice Munaretto,Nelly Rouquié,Aurélie Mougel,Malika Chassanet al. Haematologica, 2024, 109 (3), pp.809-823. ⟨10.3324/haematol.2022.282466⟩ Article dans une revue hal-04218221v1
Moesin activation controls bone resorption and tunneling nanotube-dependent osteoclast fusion Ophélie Dufrancais,Perrine Verdys,Marianna Plozza,Arnaud Métais,Marie Juzanset al. BioRxiv, 2024, ⟨10.1101/2024.05.13.593799⟩ Article dans une revue hal-04639892v1
Productive HIV-1 infection of tissue macrophages by fusion with infected CD4+ T cells Rémi Mascarau,Marie Woottum,Léa Fromont,Rémi Gence,Vincent Cantaloube-Ferrieuet al. Journal of Cell Biology, 2023, Immune Cell Biology 2023, 222 (5), pp.e202205103. ⟨10.1083/jcb.202205103⟩ Article dans une revue hal-04087834v1
Super-resolved total internal reflection fluorescence microscopy using random illuminations Kévin Affannoukoué,Simon Labouesse,Guillaume Maire,Laurent Gallais,Julien Savatieret al. Optica, 2023, 10 (8), pp.1009. ⟨10.1364/optica.487003⟩ Article dans une revue hal-04172900v1
Caspase-1-driven neutrophil pyroptosis and its role in host susceptibility to Pseudomonas aeruginosa Karin Santoni,David Pericat,Leana Gorse,Julien Buyck,Miriam Pinillaet al. PLoS Pathogens, 2022, 18 (7), pp.e1010305. ⟨10.1371/journal.ppat.1010305⟩ Article dans une revue hal-03738417v1
Dysregulation of the IFN-I signaling pathway by Mycobacterium tuberculosis leads to exacerbation of HIV-1 infection of macrophages Maeva Dupont,Thien-Phong Vu Manh,Karine Pingris,Shanti Souriant,Tomàs Velezet al. Journal of Leukocyte Biology, 2022, 112 (5), pp.1329-1342. ⟨10.1002/JLB.4MA0422-730R⟩ Article dans une revue hal-04738082v1
Nanoscale architecture and coordination of actin cores within the sealing zone of human osteoclasts Marion Portes,Thomas Mangeat,Natacha Escallier,Ophélie Dufrancais,Brigitte Raynaud-Messinaet al. eLife, 2022, 11, pp.e75610. ⟨10.7554/eLife.75610⟩ Article dans une revue hal-03763496v1
Elasticity of podosome actin networks produces nanonewton protrusive forces Marion Jasnin,Jordan Hervy,Stéphanie Balor,Anaïs Bouissou,Amsha Proaget al. Nature Communications, 2022, 13 (1), pp.3842. ⟨10.1038/s41467-022-30652-6⟩ Article dans une revue hal-03817191v1
Cellular and molecular actors of myeloid cell fusion: podosomes and tunneling nanotubes call the tune Ophélie Dufrançais,Rémi Mascarau,Renaud Poincloux,Isabelle Maridonneau-Parini,Brigitte Raynaud-Messinaet al. Cellular and Molecular Life Sciences, 2021, 78 (17-18), pp.6087-6104. ⟨10.1007/s00018-021-03875-x⟩ Article dans une revue hal-03450669v1
Super-resolved live-cell imaging using Random Illumination Microscopy Thomas Mangeat,Simon Labouesse,Marc Allain,Awoke Negash,Emmanuel Martinet al. Cell Reports Methods, 2021, 1 (1), pp.100009. ⟨10.1016/j.crmeth.2021.100009⟩ Article dans une revue hal-02564126v1
HIV-1-Infected Human Macrophages, by Secreting RANK-L, Contribute to Enhanced Osteoclast Recruitment Rémi Mascarau,Florent Bertrand,Arnaud Labrousse,Isabelle Gennero,Renaud Poinclouxet al. International Journal of Molecular Sciences, 2020, 21 (9), pp.3154. ⟨10.3390/ijms21093154⟩ Article dans une revue hal-03020912v1
Tuberculosis-associated IFN-I induces Siglec-1 on tunneling nanotubes and favors HIV-1 spread in macrophages Maeva Dupont,Shanti Souriant,Luciana Balboa,Thien-Phong Vu Manh,Karine Pingriset al. eLife, 2020, 9, ⟨10.7554/eLife.52535⟩ Article dans une revue hal-02995702v1
Genetic engineering of hoxb8 immortalized hematopoietic progenitors: a potent tool to study macrophage tissue migration Solene Accarias,Thibaut Sanchez,Arnaud Labrousse,Myriam Ben-Neji,Aurélien Boyanceet al. Journal of Cell Science, 2020, 133 (5), pp.jcs236703. ⟨10.1242/jcs.236703⟩ Article dans une revue hal-03018738v1
Tuberculosis Exacerbates HIV-1 infection through IL-10/STAT3-Dependent Tunneling Nanotube Formation in Macrophages Shanti Souriant,Luciana Balboa,Maeva Dupont,Karine Pingris,Denise Kviatcovskyet al. Cell Reports, 2019, 26 (13), pp.3586-3599.e7. ⟨10.1016/j.celrep.2019.02.091⟩ Article dans une revue hal-03034321v2
Probing the mechanical landscape – new insights into podosome architecture and mechanics Koen van den Dries,Stefan Linder,Isabelle Maridonneau-Parini,Renaud Poincloux Journal of Cell Science, 2019, 132 (24), pp.jcs236828. ⟨10.1242/jcs.236828⟩ Article dans une revue hal-03034038v1
The C-Type Lectin Receptor DC-SIGN Has an Anti-Inflammatory Role in Human M(IL-4) Macrophages in Response to Mycobacterium tuberculosis Geanncarlo Lugo-Villarino,Anthony Troegeler,Luciana Balboa,Claire Lastrucci,Carine Duvalet al. Frontiers in Immunology, 2018, 9, ⟨10.3389/fimmu.2018.01123⟩ Article dans une revue hal-02348476v1
Asb2 alpha-Filamin A Axis Is Essential for Actin Cytoskeleton Remodeling During Heart Development Arnaud Metais,Isabelle Lamsoul,Armelle Melet,Sandrine Uttenweiler-Joseph,Renaud Poinclouxet al. Circulation Research, 2018, 122 (6), pp.E34+. ⟨10.1161/CIRCRESAHA.117.312015⟩ Article dans une revue hal-02544517v1
Frustrated endocytosis controls contractility-independent mechanotransduction at clathrin-coated structures Francesco Baschieri,Stéphane Dayot,Nadia Elkhatib,Nathalie Ly,Anahi Capmanyet al. Nature Communications, 2018, 9 (1), pp.3825. ⟨10.1038/s41467-018-06367-y⟩ Article dans une revue hal-04500570v1
The Protease-Dependent Mesenchymal Migration of Tumor-Associated Macrophages as a Target in Cancer Immunotherapy Philippe Gui,Myriam Ben-Neji,Ekaterina Belozertseva,Florence Dalenc,Camille Franchetet al. Cancer Immunology Research, 2018, 6 (11), pp.1337-1351. ⟨10.1158/2326-6066.CIR-17-0746⟩ Article dans une revue hal-02356000v1
Podosomes, But Not the Maturation Status, Determine the Protease-Dependent 3D Migration in Human Dendritic Cells Céline Cougoule,Claire Lastrucci,Romain Guiet,Rémi Mascarau,Etienne Meunieret al. Frontiers in Immunology, 2018, 9, ⟨10.3389/fimmu.2018.00846⟩ Article dans une revue hal-02348486v1
Podosome Force Generation Machinery: A Local Balance between Protrusion at the Core and Traction at the Ring Christophe Thibault,Anais Bouissou,Amsha Proag,Nicolas Bourg,Karine Pingriset al. ACS Nano, 2017, 11 (4), pp.4028 - 4040. ⟨10.1021/acsnano.7b00622⟩ Article dans une revue hal-01767661v1
C-type lectin receptor DCIR modulates immunity to tuberculosis by sustaining type I interferon signaling in dendritic cells Anthony Troegeler,Ingrid Mercier,Céline Cougoule,Danilo Pietretti,André Colomet al. Proceedings of the National Academy of Sciences of the United States of America, 2017, 114 (4), pp.E540-E549. ⟨10.1073/pnas.1613254114⟩ Article dans une revue hal-02348507v1
Tuberculosis is associated with expansion of a motile, permissive and immunomodulatory CD16+ monocyte population via the IL-10/STAT3 axis Claire Lastrucci,Alan Bénard,Luciana Balboa,Karine Pingris,Shanti Souriantet al. Cell Research, 2015, 25 (12), pp.1333-1351. ⟨10.1038/cr.2015.123⟩ Article dans une revue hal-02348517v1
Working Together: Spatial Synchrony in the Force and Actin Dynamics of Podosome First Neighbors Amsha Proag,Anais Bouissou,Thomas Mangeat,Raphael Voituriez,Patrick Delobelleet al. ACS Nano, 2015, 9 (4), pp.3800 - 3813. ⟨10.1021/nn506745r⟩ Article dans une revue hal-01767608v1
Protrusion force microscopy reveals oscillatory force generation and mechanosensing activity of human macrophage podosomes Anna Labernadie,Anais Bouissou,Patrick Delobelle,Stephanie Balor,Raphael Voituriezet al. Nature Communications, 2014, 5 (1), 31p. ⟨10.1038/ncomms6343⟩ Article dans une revue hal-01767580v1
Queuosine biosynthesis is required for &lt;em&gt;sinorhizobium meliloti&lt;/em&gt;-induced cytoskeletal modifications on HeLa Cells and symbiosis with &lt;em&gt;Medicago truncatula&lt;/em&gt; Marta Marchetti,Delphine Capela,Renaud Poincloux,Nacer Benmeradi,Marie-Christine Auriacet al. PLoS ONE, 2013, 8 (2), ⟨10.1371/journal.pone.0056043⟩ Article dans une revue hal-02650924v1
Macrophage Mesenchymal Migration Requires Podosome Stabilization by Filamin A Romain Guiet,Christel Vérollet,Isabelle Lamsoul,Céline Cougoule,Renaud Poinclouxet al. Journal of Biological Chemistry, 2012, 287 (16), pp.13051-13062. ⟨10.1074/jbc.M111.307124⟩ Article dans une revue hal-02406507v1
Mycobacterial p(1)-type ATPases mediate resistance to zinc poisoning in human macrophages. Hélène Botella,Pascale Peyron,Florence Levillain,Renaud Poincloux,Yannick Poquetet al. Cell Host and Microbe, 2011, 10 (3), pp.248-59. ⟨10.1016/j.chom.2011.08.006⟩ Article dans une revue hal-00674577v1
Macrophage podosomes go 3D Emeline van Goethem,Romain Guiet,Stephanie Balor,Guillaume Charriere,Renaud Poinclouxet al. European Journal of Cell Biology, 2011, 90 (2-3), pp.224-236. ⟨10.1016/j.ejcb.2010.07.011⟩ Article dans une revue istex hal-02356068v1
Matrix architecture dictates three-dimensional migration modes of human macrophages: differential involvement of proteases and podosome-like structures. Emeline van Goethem,Renaud Poincloux,Fabienne Gauffre,Isabelle Maridonneau-Parini,Véronique Le Cabec Journal of Immunology, 2010, 184 (2), pp.1049-61. ⟨10.4049/jimmunol.0902223⟩ Article dans une revue hal-03038501v1
Three-dimensional migration of macrophages requires Hck for podosome organization and extracellular matrix proteolysis Céline Cougoule,Véronique Le Cabec,Renaud Poincloux,Talal Al Saati,Jean-Louis Megeet al. Blood, 2010, 115 (7), pp.1444-1452. ⟨10.1182/blood-2009-04-218735⟩ Article dans une revue hal-02356257v1
The oncogenic activity of the Src family kinase Hck requires the cooperative action of the plasma membrane- and lysosome-associated isoforms Renaud Poincloux,Talal Al Saati,Isabelle Maridonneau-Parini,Véronique Le Cabec European Journal of Cancer, 2009, 45 (3), pp.321-327. ⟨10.1016/j.ejca.2008.11.020⟩ Article dans une revue istex hal-02356076v1
Diaphanous-related formins are required for invadopodia formation and invasion of breast tumor cells Floria Lizarraga,Renaud Poincloux,Marise Romao,Guillaume Montagnac,Gaëlle Le Dezet al. Cancer Research, 2009, 69 (7), pp.2792-2800. ⟨10.1158/0008-5472.CAN-08-3709⟩ Article dans une revue hal-02659942v1
Hematopoietic cell kinase (Hck) isoforms and phagocyte duties – From signaling and actin reorganization to migration and phagocytosis R Guiet,R. Poincloux,J. Castandet,L. Marois,A. Labrousseet al. European Journal of Cell Biology, 2008, 87 (8-9), pp.527-542. ⟨10.1016/j.ejcb.2008.03.008⟩ Article dans une revue istex hal-02356077v1
MT1-MMP-dependent invasion is regulated by TI-VAMP/VAMP7. Anika Steffen,Gaëlle Le Dez,Renaud Poincloux,Chiara Recchi,Pierre Nassoyet al. Current Biology, 2008, 18 (12), pp.926-31. ⟨10.1016/j.cub.2008.05.044⟩ Article dans une revue hal-00319422v1
Tyrosine-phosphorylated STAT5 accumulates on podosomes in Hck-transformed fibroblasts and chronic myeloid leukemia cells. Renaud Poincloux,Céline Cougoule,Thomas Daubon,Isabelle Maridonneau-Parini,Véronique Le Cabec Journal of Cellular Physiology, 2007, 213 (1), pp.212-20. ⟨10.1002/jcp.21112⟩ Article dans une revue istex hal-00177912v1
Re-arrangements of podosome structures are observed when Hck is activated in myeloid cells. Renaud Poincloux,Claire Vincent,Arnaud Labrousse,Jerôme Castandet,Maxime Rigoet al. European Journal of Cell Biology, 2006, 85 (3-4), pp.327-32. ⟨10.1016/j.ejcb.2005.09.012⟩ Article dans une revue istex hal-00177921v1
Activation of the lysosome-associated p61Hck isoform triggers the biogenesis of podosomes. Céline Cougoule,Sébastien Carréno,Jerôme Castandet,Arnaud Labrousse,Catherine Astarie-Dequekeret al. Traffic, 2005, 6 (8), pp.682-94. ⟨10.1111/j.1600-0854.2005.00307.x⟩ Article dans une revue hal-00177916v1
Fungal lectin, XCL, is internalized via clathrin-dependent endocytosis and facilitates uptake of other molecules. Frédéric Francis,Claire Marty-Detraves,Renaud Poincloux,Laurent Baricault,Didier Fournieret al. European Journal of Cell Biology, 2003, 82 (10), pp.515-22. ⟨10.1078/0171-9335-00338⟩ Article dans une revue hal-00177744v1

Communication dans un congrès (8)

Macrophage mechanics, from cell migration to phagocytosis Renaud Poincloux Immunobiophysics seminar series, Mar 2025, Online, France Communication dans un congrès hal-05018885v1
Macrophage mechanics, from cell migration to phagocytosis Renaud Poincloux Symposium on Monocytes and Macrophages, Nov 2025, Lyon, France Communication dans un congrès hal-05018878v1
Macrophage mechanics, from cell migration to phagocytosis Renaud Poincloux 20th meeting of the Canceropole GSO, Nov 2024, Perpignan, France Communication dans un congrès hal-05019217v1
ERM proteins and the macrophage cortex Renaud Poincloux Les Avancées Scientifiques de la Recherche Biomédicale Toulousaine, Nov 2024, Toulouse, France Communication dans un congrès hal-05019226v1
Macrophage compression forces during migration and phagocytosis Renaud Poincloux Cellular and Molecular Organisation on Engineered Micropatterns and 3D Structures, Nov 2023, Paris, France Communication dans un congrès hal-05019236v1
Nanoscale mechanics of macrophage podosomes Renaud Poincloux ENS/ESPCI biophysics seminars, Apr 2021, Online, France Communication dans un congrès hal-05019249v1
Nanoscale architecture and mechanics of macrophage podosomes Renaud Poincloux Invadosome meeting, Jun 2019, London, United Kingdom Communication dans un congrès hal-05019265v1
Nanoscale architecture and mechanics of macrophage podosomes Renaud Poincloux CellTiss days, Nov 2019, Giens, France Communication dans un congrès hal-05019258v1

Pré-publication, Document de travail (9)

Identification of a unique TUBB3 + cell population in the tuberculosis granuloma Sarah Monard,Arnaud Métais,Maxime Pingret,Caroline Buscail,Maxime Caouailleet al. 2025 Pré-publication, Document de travail hal-05018831v1
4polar3D : Single molecule 3D orientation imaging of dense actin networks using ratiometric polarization splitting Charitra S. Senthil Kumar,Cesar Augusto Valades-Cruz,Miguel Sison,Arturo G Vesga,Javier Rey-Barrosoet al. 2025 Pré-publication, Document de travail hal-05170251v1
Dual human lung models reveal compartment-specific activity of anti-tuberculosis drugs and host-directed therapies Caio César Barbosa Bomfim,Natacha Faivre,Thomas Benoist,Manon Popis,Bastien Suireet al. 2025 Pré-publication, Document de travail hal-05379754v1
Inhibition of glycolysis in tuberculosis-mediated metabolic rewiring reduces HIV-1 spread across macrophages Zoï Vahlas,Natacha Faivre,Sarah C Monard,Quentin Hertel,Mariano Maioet al. 2024 Pré-publication, Document de travail hal-04739994v1
Moesin controls cell-cell fusion and osteoclast function Ophélie Dufrancais,Perrine Verdys,Marianna Plozza,Arnaud Métais,Marie Juzanset al. 2025 Pré-publication, Document de travail hal-04958903v1
The membrane-actin linkers ezrin, radixin, and moesin are dispensable for macrophage migration and cortex mechanics Perrine Verdys,Javier Rey Barroso,Joseph Vermeil,Thibaut Sanchez,Arnaud Métaiset al. 2023 Pré-publication, Document de travail hal-04234772v1
Elasticity of dense actin networks produces nanonewton protrusive forces Marion Jasnin,Jordan Hervy,Stéphanie Balor,Anais Bouissou,Amsha Proaget al. 2021 Pré-publication, Document de travail hal-03423297v1
Super-resolved live-cell imaging using Random Illumination Microscopy Thomas Mangeat,Simon Labouesse,Marc Allain,Emmanuel Martin,Renaud Poinclouxet al. 2021 Pré-publication, Document de travail hal-03101965v1
Pseudomonas aeruginosa infection reveals a Caspase-1-dependent neutrophil pyroptosis pathway that restrains damaging Histone release Rémi Planès,Karin Santoni,Salimata Bagayoko,David Pericat,Pierre-Jean Bordignonet al. 2021 Pré-publication, Document de travail hal-03452379v1