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Robert THAI



Ligand‐directed modification of active matrix metalloproteases: activity‐based probes with no photolabile group

Monika Kaminska , Pierrick Bruyat , Carole Malgorn , Marion Doladilhe , Evelyne Cassar-Lajeunesse
Angewandte Chemie International Edition, 2021, 60 (33), pp.18272-18279. ⟨10.1002/anie.202106117⟩
Journal articles hal-03965993v2
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Mambalgin-1 pain-relieving peptide locks the hinge between α4 and α5 helices to inhibit rat Acid-Sensing Ion Channel 1a

Miguel Salinas , Pascal Kessler , Dominique Douguet , Daad Sarraf , Nicolo Tonali
Neuropharmacology, 2021, 185, pp.108453. ⟨10.1016/j.neuropharm.2021.108453⟩
Journal articles hal-03115234v1
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Di-phosphorylated BAF shows altered structural dynamics and binding to DNA, but interacts with its nuclear envelope partners

Agathe Marcelot , Ambre Petitalot , Virginie Ropars , Marie-Hélène Le du , Camille Samson
Nucleic Acids Research, 2021, 49 (7), pp.3841-3855. ⟨10.1093/nar/gkab184⟩
Journal articles cea-03247357v1
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A Comprehensive Overview of the Cyclodipeptide Synthase Family Enriched with the Characterization of 32 New Enzymes

Muriel Gondry , Isabelle Jacques , Robert Thai , Morgan Babin , Nicolas Canu
Frontiers in Microbiology, 2018, 9, pp.46. ⟨10.3389/fmicb.2018.00046⟩
Journal articles cea-01988448v1

Incorporation of non-canonical amino acids into 2,5-diketopiperazines by cyclodipeptide synthases

Nicolas Canu , Pascal Belin , Robert Thai , Isabelle Correia , Olivier Lequin
Angewandte Chemie International Edition, 2018, 57 (12), pp.3118-3122. ⟨10.1002/anie.201712536⟩
Journal articles cea-01988447v1

Sydnone-coumarins as clickable turn-on fluorescent sensors for molecular imaging

Elodie Decuypere , Margaux Riomet , Antoine Sallustrau , Sarah Bregant , Robert Thai
Chemical Communications, 2018, 54 (76), pp.10758-10761. ⟨10.1039/c8cc06070c⟩
Journal articles cea-01988433v1
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DMF-MALDI: droplet based microfluidic combined to MALDI-TOF for focused peptide detection

Kiarach Mesbah , Robert Thai , Sarah Bregant , Florent Malloggi
Scientific Reports, 2017, 7 (1), pp.6756. ⟨10.1038/s41598-017-06660-8⟩
Journal articles cea-01570543v1
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A higher-order entity formed by the flexible assembly of RAP1 with TRF2

Guillaume Gaullier , Simona Miron , Sabrina Pisano , Rémi Buisson , Yann-Vaï Le Bihan
Nucleic Acids Research, 2016, 44 (4), pp.1962-1976. ⟨10.1093/nar/gkv1531⟩
Journal articles hal-01346908v1

Analysis of 51 cyclodipeptide synthases reveals the basis for substrate specificity.

Isabelle B Jacques , Mireille Moutiez , Jerzy Witwinowski , Emmanuelle Darbon , Cécile Martel
Nature Chemical Biology, 2015, 11 (9), pp.721-7. ⟨10.1038/nchembio.1868⟩
Journal articles hal-01430815v1

Diversified targets of FKBP25 and its complex with rapamycin

Andrzej Galat , Robert Thai , Enrico Stura
International Journal of Biological Macromolecules, 2014, 69 (4), pp.344-352
Journal articles hal-02000274v1

Isolation, purification and functional characterization of alpha-BnIA from Conus bandanus venom.

Bao Nguyen , Jean-Pierre Le Caer , Romulo Aráoz , Robert Thai , Hung Lamthanh
Toxicon, 2014, 91, pp.1551-63
Journal articles hal-01112222v1
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Characterization of a novel Conus bandanus conopeptide belonging to the M-superfamily containing bromotryptophan.

Bao Nguyen , Jean-Pierre Le Caer , Gilles Mourier , Robert Thai , Hung Lamthanh
Marine drugs, 2014, 12 (6), pp.3449-3465. ⟨10.3390/md12063449⟩
Journal articles hal-01020530v1
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Unravelling the mechanism of non-ribosomal peptide synthesis by cyclodipeptide synthases.

Mireille Moutiez , Emmanuelle Schmitt , Jérôme Seguin , Robert Thai , Emmanuel Favry
Nature Communications, 2014, 5 (October), pp.5141. ⟨10.1038/ncomms6141⟩
Journal articles hal-01098814v1

Rapamycin-binding FKBP25 associates with diverse proteins that form large intracellular entities

Andrzej Galat , Robert Thai
Biochemical and Biophysical Research Communications, 2014, 450 (4), pp.1255-1260
Journal articles cea-01989339v1

Post-PKS Tailoring Steps of the Spiramycin Macrolactone Ring in Streptomyces ambofaciens.

Hoang-Chuong Nguyen , Emmanuelle Darbon , Robert Thai , Jean-Luc Pernodet , Sylvie Lautru
Antimicrobial Agents and Chemotherapy, 2013, 57 (8), pp.3836-42. ⟨10.1128/AAC.00512-13⟩
Journal articles hal-00848145v1
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High throughput screening identifies disulfide isomerase DsbC as a very efficient partner for recombinant expression of small disulfide-rich proteins in E. coli

Hervé Nozach , Carole Fruchart-Gaillard , François Fenaille , Fabrice Beau , Oscar Pereira Ramos
Microbial Cell Factories, 2013, 12, ⟨10.1186/1475-2859-12-37⟩
Journal articles cea-02100032v1

Substrate and reaction specificity of Mycobacterium tuberculosis cytochrome P450 CYP121: insights from biochemical studies and crystal structures.

Matthieu Fonvielle , Marie-Helene Le Du , Olivier Lequin , Alain Lecoq , Mickael Jacquet
Journal of Biological Chemistry, 2013, 288, pp.17347-17359. ⟨10.1074/jbc.M112.443853⟩
Journal articles hal-00818752v1

Implication of cysteine residues in the selection of oxorhenium inhibitors of cyclophilin hCyp18

Cécile Clavaud , Julien Le Gal , Robert Thai , Christophe Dugave
Metallomics, 2012, 4 (2), pp.179
Journal articles cea-01989670v1

Cyclodipeptide synthases, a family of class-I aminoacyl-tRNA synthetase-like enzymes involved in non-ribosomal peptide synthesis

Ludovic Sauguet , Mireille Moutiez , Yan Li , Pascal Belin , Jérôme Seguin
Nucleic Acids Research, 2011, 39 (10), pp.4475-4489. ⟨10.1093/nar/gkr027⟩
Journal articles cea-02000061v1

Stabilization of HIV-1 Envelope in the CD4-bound Conformation through Specific Cross-linking of a CD4 Mimetic

Grégoire Martin , Brian Burke , Robert Thai , Antu Dey , Olivier Combes
Journal of Biological Chemistry, 2011, 286 (24), pp.21706-21716
Journal articles cea-01989703v1

Oxorhenium-Mediated Assembly of Noncyclic Selective Integrin Antagonists: A Combinatorial Approach

Marie Aufort , Marta Gonera , Julien Le Gal , Bertrand Czarny , Loic Le Clainche
ChemBioChem, 2011, 12 (4), pp.583-592
Journal articles cea-01989787v1

Oxorhenium-Mediated Assembly of Noncyclic Selective Integrin Antagonists: A Combinatorial Approach

Marie Aufort , Marta Gonera , Julien Le Gal , Bertrand Czarny , Loic Le Clainche
ChemBioChem, 2011, 12 (4), pp.583-592
Journal articles cea-02000371v1

Oxorhenium-Mediated Assembly of Noncyclic Selective Integrin Antagonists: A Combinatorial Approach

Marie Aufort , Marta Gonera , Julien Le Gal , Bertrand Czarny , Loic Le Clainche
ChemBioChem, 2011, 12 (4), pp.583-592
Journal articles cea-01997597v1

Synthesis, in vitro screening and in vivo evaluation of cyclic RGD analogs cyclized through oxorhenium and oxotechnetium coordination

Marie Aufort , Marta Gonera , Marie Lelait , Bertrand Czarny , Loic Le Clainche
European Journal of Medicinal Chemistry, 2011, 46 (5), pp.1779-1788
Journal articles cea-01989729v1

Structural identification by mass spectrometry of a novel antimicrobial peptide from the venom of the solitary bee Osmia rufa (Hymenoptera: Megachilidae)

Reto Stocklin , Philippe Favreau , Robert Thai , Jochen Pflugfelder , Philippe Bulet
Toxicon, 2010, 55 (1), pp.20-27
Journal articles cea-01996927v1

Isolation and pharmacological characterization of AdTx1, a natural peptide displaying specific insurmountable antagonism of the alpha(1A)-adrenoceptor.

L. Quinton , Emmanuelle Girard , A. Maiga , M. Rekik , P. Lluel
British Journal of Pharmacology, 2010, 159 (2), pp.316-25. ⟨10.1111/j.1476-5381.2009.00532.x⟩
Journal articles hal-00426559v1

Footprinting of protein interactions by tritium labeling

Guillaume Mousseau , Quentin Raffy , Olivier Thomas , Morgane Agez , Robert Thai
British Journal of Pharmacology, 2010, 159 (2), pp.316-325. ⟨10.1021/bi100031a⟩
Journal articles cea-02000386v1

Identification of a novel snake peptide toxin displaying high affinity and antagonist behaviour for the α(2) -adrenoceptors.

Céline Rouget , Loïc Quinton , Arhamatoulaye Maïga , Céline Gales , Geoffrey Masuyer
British Journal of Pharmacology, 2010, epub ahead of print. ⟨10.1111/j.1476-5381.2010.00966.x⟩
Journal articles hal-00528529v1

Isolation and pharmacological characterization of AdTx1, a natural peptide displaying specific insurmountable antagonism of the α1A-adrenoceptor

L. Quinton , Emmanuelle Girard , A. Maiga , M. Rekik , P. Lluel
British Journal of Pharmacology, 2010, 159 (2), pp.316-325. ⟨10.1111/j.1476-5381.2009.00532.x⟩
Journal articles cea-02000545v1

Cyclodipeptide synthases are a family of tRNA-dependent peptide bond–forming enzymes

Muriel Gondry , Ludovic Sauguet , Pascal Belin , Robert Thai , Rachel Amouroux
Nature Chemical Biology, 2009, 5 (6), pp.414-420. ⟨10.1038/nchembio.175⟩
Journal articles cea-02000100v1

Identification and structural basis of the reaction catalyzed by CYP121, an essential cytochrome P450 in Mycobacterium tuberculosis

Pascal Belin , Marie-Hélène Le Du , A. Fielding , O. Lequin , M. Jacquet
Proceedings of the National Academy of Sciences of the United States of America, 2009, 106 (18), pp.7426-7431. ⟨10.1073/pnas.0812191106⟩
Journal articles cea-01997903v1

Covalent Modification of Matrix Metalloproteinases by a Photoaffinity Probe: Influence of Nucleophilicity and Flexibility of the Residue in Position 241

Anne-Sophie Dabert-Gay , Bertrand Czarny , Evelyne Lajeunesse , Robert Thai , Hideaki Nagase
Bioconjugate Chemistry, 2009, 20 (2), pp.367-375
Journal articles cea-02000614v1

Detection of Matrix Metalloproteinase Active Forms in Complex Proteomes: Evaluation of Affinity versus Photoaffinity Capture

Sarah Bregant , Céline Huillet , Laurent Devel , Anne-Sophie Dabert-Gay , Fabrice Beau
Journal of Proteome Research, 2009, 8 (5), pp.2484-2494
Journal articles cea-02000592v1

Increasing the humoral immunogenic properties of the HIV-1 Tat protein using a ligand-stabilizing strategy

Alain Lecoq , Gervaise Moine , Laurent Bellanger , Pascal Drevet , Robert Thai
Vaccine, 2008, 26 (21), pp.2615-2626
Journal articles cea-01997094v1

Molecular Determinants of Matrix Metalloproteinase-12 Covalent Modification by a Photoaffinity Probe

Anne-Sophie Dabert-Gay , Bertrand Czarny , Laurent Devel , Fabrice Beau , Evelyne Lajeunesse
Journal of Biological Chemistry, 2008, 283 (45), pp.31058-31067
Journal articles cea-01997000v1

Dynamic Combinatorial Self‐Assembly of Cyclophilin hCyp‐18 Ligands through Oxorhenium Coordination

Cécile Clavaud , Julien Le Gal , Robert Thai , Mireille Moutiez , Christophe Dugave
ChemBioChem, 2008, 9 (11), pp.1823-1829
Journal articles cea-01997014v1

Purification and characterization of cassiicolin, the toxin produced by Corynespora cassiicola, causal agent of the leaf fall disease of rubber tree

Frédéric de Lamotte , Marie-Pierre Duviau , Christine Sanier , Robert Thai , Joël Poncet
Journal of Chromatography B - Analytical Technologies in the Biomedical and Life Sciences, 2007, 849 (1-2), pp.357-362. ⟨10.1016/j.jchromb.2006.10.051⟩
Journal articles hal-02668494v1

Structural analysis of cassiicolin, a host-selective protein toxin from Corynespora cassiicola

Philippe Barthe , Valérie Pujade-Renaud , Frédéric Breton , Daniel Gargani , Robert Thai
Journal of Molecular Biology, 2007, 367 (1), pp.89-101. ⟨10.1016/j.jmb.2006.11.086⟩
Journal articles hal-02665937v1

Localization and Quantification of Carbon-Centered Radicals on Any Amino Acid of a Protein

G. Mousseau , O. Thomas , S. Oppilliart , A. Coirier , A. Salcedo-Serna
Analytical Chemistry, 2007, 79 (14), pp.5444-5448
Journal articles cea-02003859v1

Identification of a New Natural Ara h 6 Isoform and of Its Proteolytic Product as Major Allergens in Peanut

H. Bernard , L. Mondoulet , M.F. Drumare , E. Paty , P. Scheinmann
Journal of Agricultural and Food Chemistry, 2007, 55 (23), pp.9663-9669. ⟨10.1021/jf071424g⟩
Journal articles cea-02003381v1

The venom of the snake genus Atheris contains a new class of peptides with clusters of histidine and glycine residues.

Philippe Favreau , Olivier Cheneval , Laure Menin , Sophie Michalet , Hubert Gaertner
Rapid Communications in Mass Spectrometry, 2007, 21 (3), pp.406-12. ⟨10.1002/rcm.2853⟩
Journal articles hal-00286195v1

Siderophore peptide, a new type of post-translationally modified antibacterial peptide with potent activity.

Xavier Thomas , Delphine Destoumieux-Garzón , Jean Peduzzi , Carlos Afonso , Alain Blond
Journal of Biological Chemistry, 2004, 279 (27), pp.28233-42. ⟨10.1074/jbc.M400228200⟩
Journal articles hal-00016010v1

A synthetic weak neurotoxin binds with low affinity to Torpedo and chicken alpha7 nicotinic acetylcholine receptors.

Siew Lay Poh , Gilles Mourier , Robert Thai , Arunmozhiarasi Armugam , Jordi Molgó
European Journal of Biochemistry, 2002, 269 (17), pp.4247-56. ⟨10.1046/j.1432-1033.2002.03113.x⟩
Journal articles hal-00193986v1

Increasing immunogenicity of antigens fused to Ig-binding proteins by cell surface targeting.

M Léonetti , Robert Thai , J Cotton , S Leroy , P Drevet
Journal of Immunology, 1998, 160 (8), pp.3820-7
Journal articles hal-03038950v1

A particularly labile Asp-Pro bond in the green mamba muscarinic toxin MTX2. Effect of protein conformation on the rate of cleavage

Isabelle Ségalas , Robert Thai , Renée Ménez Claudio Vita
FEBS Letters, 1995, 371 (2), pp.171-175. ⟨10.1016/0014-5793(95)00844-y⟩
Journal articles hal-03038921v1

Ultra-sensitive detection method with droplet nased microfluidic coupled to MALDI-TOF

Kiarach Mesbah , Sarah Bregant , Robert Thai , Vincent Dive , Florent Malloggi
20th International Conference on Miniaturized Systems for Chemistry and Life Sciences (MicroTAS 2016), Oct 2016, Dublin, Ireland
Conference papers cea-02368306v1