Robert THAI

Publications

Article dans une revue (47)

In-cell residue-resolved NMR of micromolar α-synuclein and tau at 310K Hélène Chérot,Théophile Pred’homme,Robert Thai,Frédéric Théodoro,Florence Castelliet al. Journal of the American Chemical Society, 2025, 147 (50), pp.46259. ⟨10.1021/jacs.5c15061⟩ Article dans une revue hal-04752446v2
Covalent labeling of Matrix Metalloproteases with affinity‐based probes containing tuned reactive N‐acyl‐N‐alkyl sulfonamide cleavable linkers Laurent Devel,Carole Malgorn,Regis-William Tohon,Marie Launay,Konstantinos Patiniotiset al. ChemBioChem, 2024, 25 (23), pp.e202400441. ⟨10.1002/cbic.202400441⟩ Article dans une revue hal-04740309v1
Mambalgin-1 pain-relieving peptide locks the hinge between α4 and α5 helices to inhibit rat Acid-Sensing Ion Channel 1a Miguel Salinas,Pascal Kessler,Dominique Douguet,Daad Sarraf,Nicolo Tonaliet al. Neuropharmacology, 2021, 185, pp.108453. ⟨10.1016/j.neuropharm.2021.108453⟩ Article dans une revue hal-03115234v1
Di-phosphorylated BAF shows altered structural dynamics and binding to DNA, but interacts with its nuclear envelope partners Agathe Marcelot,Ambre Petitalot,Virginie Ropars,Marie-Hélène Le du,Camille Samsonet al. Nucleic Acids Research, 2021, 49 (7), pp.3841-3855. ⟨10.1093/nar/gkab184⟩ Article dans une revue cea-03247357v1
Ligand‐directed modification of active matrix metalloproteases: activity‐based probes with no photolabile group Monika Kaminska,Pierrick Bruyat,Carole Malgorn,Marion Doladilhe,Evelyne Cassar-Lajeunesseet al. Angewandte Chemie International Edition, 2021, 60 (33), pp.18272-18279. ⟨10.1002/anie.202106117⟩ Article dans une revue hal-03965993v2
A Comprehensive Overview of the Cyclodipeptide Synthase Family Enriched with the Characterization of 32 New Enzymes Muriel Gondry,Isabelle Jacques,Robert Thai,Morgan Babin,Nicolas Canuet al. Frontiers in Microbiology, 2018, 9, pp.46. ⟨10.3389/fmicb.2018.00046⟩ Article dans une revue cea-01988448v1
Sydnone-coumarins as clickable turn-on fluorescent sensors for molecular imaging Elodie Decuypere,Margaux Riomet,Antoine Sallustrau,Sarah Bregant,Robert Thaiet al. Chemical Communications, 2018, 54 (76), pp.10758-10761. ⟨10.1039/c8cc06070c⟩ Article dans une revue cea-01988433v1
Incorporation of non-canonical amino acids into 2,5-diketopiperazines by cyclodipeptide synthases Nicolas Canu,Pascal Belin,Robert Thai,Isabelle Correia,Olivier Lequinet al. Angewandte Chemie International Edition, 2018, 57 (12), pp.3118-3122. ⟨10.1002/anie.201712536⟩ Article dans une revue cea-01988447v1
DMF-MALDI: droplet based microfluidic combined to MALDI-TOF for focused peptide detection Kiarach Mesbah,Robert Thai,Sarah Bregant,Florent Malloggi Scientific Reports, 2017, 7 (1), pp.6756. ⟨10.1038/s41598-017-06660-8⟩ Article dans une revue cea-01570543v1
A higher-order entity formed by the flexible assembly of RAP1 with TRF2 Guillaume Gaullier,Simona Miron,Sabrina Pisano,Rémi Buisson,Yann-Vaï Le Bihanet al. Nucleic Acids Research, 2016, 44 (4), pp.1962-1976. ⟨10.1093/nar/gkv1531⟩ Article dans une revue hal-01346908v1
Analysis of 51 cyclodipeptide synthases reveals the basis for substrate specificity. Isabelle B Jacques,Mireille Moutiez,Jerzy Witwinowski,Emmanuelle Darbon,Cécile Martelet al. Nature Chemical Biology, 2015, 11 (9), pp.721-7. ⟨10.1038/nchembio.1868⟩ Article dans une revue hal-01430815v1
Diversified targets of FKBP25 and its complex with rapamycin Andrzej Galat,Robert Thai,Enrico Stura International Journal of Biological Macromolecules, 2014, 69 (4), pp.344-352 Article dans une revue hal-02000274v1
Unravelling the mechanism of non-ribosomal peptide synthesis by cyclodipeptide synthases. Mireille Moutiez,Emmanuelle Schmitt,Jérôme Seguin,Robert Thai,Emmanuel Favryet al. Nature Communications, 2014, 5 (October), pp.5141. ⟨10.1038/ncomms6141⟩ Article dans une revue hal-01098814v1
Characterization of a novel Conus bandanus conopeptide belonging to the M-superfamily containing bromotryptophan. Bao Nguyen,Jean-Pierre Le Caer,Gilles Mourier,Robert Thai,Hung Lamthanhet al. Marine drugs, 2014, 12 (6), pp.3449-3465. ⟨10.3390/md12063449⟩ Article dans une revue hal-01020530v1
Isolation, purification and functional characterization of alpha-BnIA from Conus bandanus venom. Bao Nguyen,Jean-Pierre Le Caer,Romulo Aráoz,Robert Thai,Hung Lamthanhet al. Toxicon, 2014, 91, pp.1551-63 Article dans une revue hal-01112222v1
Rapamycin-binding FKBP25 associates with diverse proteins that form large intracellular entities Andrzej Galat,Robert Thai Biochemical and Biophysical Research Communications, 2014, 450 (4), pp.1255-1260 Article dans une revue cea-01989339v1
Substrate and reaction specificity of Mycobacterium tuberculosis cytochrome P450 CYP121: insights from biochemical studies and crystal structures. Matthieu Fonvielle,Marie-Helene Le Du,Olivier Lequin,Alain Lecoq,Mickael Jacquetet al. Journal of Biological Chemistry, 2013, 288, pp.17347-17359. ⟨10.1074/jbc.M112.443853⟩ Article dans une revue hal-00818752v1
High throughput screening identifies disulfide isomerase DsbC as a very efficient partner for recombinant expression of small disulfide-rich proteins in E. coli Hervé Nozach,Carole Fruchart-Gaillard,François Fenaille,Fabrice Beau,Oscar Pereira Ramoset al. Microbial Cell Factories, 2013, 12, ⟨10.1186/1475-2859-12-37⟩ Article dans une revue cea-02100032v1
Post-PKS Tailoring Steps of the Spiramycin Macrolactone Ring in Streptomyces ambofaciens. Hoang-Chuong Nguyen,Emmanuelle Darbon,Robert Thai,Jean-Luc Pernodet,Sylvie Lautru Antimicrobial Agents and Chemotherapy, 2013, 57 (8), pp.3836-42. ⟨10.1128/AAC.00512-13⟩ Article dans une revue hal-00848145v1
Implication of cysteine residues in the selection of oxorhenium inhibitors of cyclophilin hCyp18 Cécile Clavaud,Julien Le Gal,Robert Thai,Christophe Dugave Metallomics, 2012, 4 (2), pp.179 Article dans une revue cea-01989670v1
Stabilization of HIV-1 Envelope in the CD4-bound Conformation through Specific Cross-linking of a CD4 Mimetic Grégoire Martin,Brian Burke,Robert Thai,Antu Dey,Olivier Combeset al. Journal of Biological Chemistry, 2011, 286 (24), pp.21706-21716 Article dans une revue cea-01989703v1
Oxorhenium-Mediated Assembly of Noncyclic Selective Integrin Antagonists: A Combinatorial Approach Marie Aufort,Marta Gonera,Julien Le Gal,Bertrand Czarny,Loic Le Claincheet al. ChemBioChem, 2011, 12 (4), pp.583-592 Article dans une revue cea-01989787v1
Oxorhenium-Mediated Assembly of Noncyclic Selective Integrin Antagonists: A Combinatorial Approach Marie Aufort,Marta Gonera,Julien Le Gal,Bertrand Czarny,Loic Le Claincheet al. ChemBioChem, 2011, 12 (4), pp.583-592 Article dans une revue cea-02000371v1
Cyclodipeptide synthases, a family of class-I aminoacyl-tRNA synthetase-like enzymes involved in non-ribosomal peptide synthesis Ludovic Sauguet,Mireille Moutiez,Yan Li,Pascal Belin,Jérôme Seguinet al. Nucleic Acids Research, 2011, 39 (10), pp.4475-4489. ⟨10.1093/nar/gkr027⟩ Article dans une revue cea-02000061v1
Oxorhenium-Mediated Assembly of Noncyclic Selective Integrin Antagonists: A Combinatorial Approach Marie Aufort,Marta Gonera,Julien Le Gal,Bertrand Czarny,Loic Le Claincheet al. ChemBioChem, 2011, 12 (4), pp.583-592 Article dans une revue cea-01997597v1
Synthesis, in vitro screening and in vivo evaluation of cyclic RGD analogs cyclized through oxorhenium and oxotechnetium coordination Marie Aufort,Marta Gonera,Marie Lelait,Bertrand Czarny,Loic Le Claincheet al. European Journal of Medicinal Chemistry, 2011, 46 (5), pp.1779-1788 Article dans une revue cea-01989729v1
Identification of a novel snake peptide toxin displaying high affinity and antagonist behaviour for the α(2) -adrenoceptors. Céline Rouget,Loïc Quinton,Arhamatoulaye Maïga,Céline Gales,Geoffrey Masuyeret al. British Journal of Pharmacology, 2010, epub ahead of print. ⟨10.1111/j.1476-5381.2010.00966.x⟩ Article dans une revue hal-00528529v1
Isolation and pharmacological characterization of AdTx1, a natural peptide displaying specific insurmountable antagonism of the alpha(1A)-adrenoceptor. L. Quinton,Emmanuelle Girard,A. Maiga,M. Rekik,P. Lluelet al. British Journal of Pharmacology, 2010, 159 (2), pp.316-25. ⟨10.1111/j.1476-5381.2009.00532.x⟩ Article dans une revue hal-00426559v1
Footprinting of protein interactions by tritium labeling Guillaume Mousseau,Quentin Raffy,Olivier Thomas,Morgane Agez,Robert Thaiet al. British Journal of Pharmacology, 2010, 159 (2), pp.316-325. ⟨10.1021/bi100031a⟩ Article dans une revue cea-02000386v1
Structural identification by mass spectrometry of a novel antimicrobial peptide from the venom of the solitary bee Osmia rufa (Hymenoptera: Megachilidae) Reto Stocklin,Philippe Favreau,Robert Thai,Jochen Pflugfelder,Philippe Buletet al. Toxicon, 2010, 55 (1), pp.20-27 Article dans une revue cea-01996927v1
Isolation and pharmacological characterization of AdTx1, a natural peptide displaying specific insurmountable antagonism of the α1A-adrenoceptor L. Quinton,Emmanuelle Girard,A. Maiga,M. Rekik,P. Lluelet al. British Journal of Pharmacology, 2010, 159 (2), pp.316-325. ⟨10.1111/j.1476-5381.2009.00532.x⟩ Article dans une revue cea-02000545v1
Cyclodipeptide synthases are a family of tRNA-dependent peptide bond–forming enzymes Muriel Gondry,Ludovic Sauguet,Pascal Belin,Robert Thai,Rachel Amourouxet al. Nature Chemical Biology, 2009, 5 (6), pp.414-420. ⟨10.1038/nchembio.175⟩ Article dans une revue cea-02000100v1
Identification and structural basis of the reaction catalyzed by CYP121, an essential cytochrome P450 in Mycobacterium tuberculosis Pascal Belin,Marie-Hélène Le Du,A. Fielding,O. Lequin,M. Jacquetet al. Proceedings of the National Academy of Sciences of the United States of America, 2009, 106 (18), pp.7426-7431. ⟨10.1073/pnas.0812191106⟩ Article dans une revue cea-01997903v1
Covalent Modification of Matrix Metalloproteinases by a Photoaffinity Probe: Influence of Nucleophilicity and Flexibility of the Residue in Position 241 Anne-Sophie Dabert-Gay,Bertrand Czarny,Evelyne Lajeunesse,Robert Thai,Hideaki Nagaseet al. Bioconjugate Chemistry, 2009, 20 (2), pp.367-375 Article dans une revue cea-02000614v1
Detection of Matrix Metalloproteinase Active Forms in Complex Proteomes: Evaluation of Affinity versus Photoaffinity Capture Sarah Bregant,Céline Huillet,Laurent Devel,Anne-Sophie Dabert-Gay,Fabrice Beauet al. Journal of Proteome Research, 2009, 8 (5), pp.2484-2494 Article dans une revue cea-02000592v1
Molecular Determinants of Matrix Metalloproteinase-12 Covalent Modification by a Photoaffinity Probe Anne-Sophie Dabert-Gay,Bertrand Czarny,Laurent Devel,Fabrice Beau,Evelyne Lajeunesseet al. Journal of Biological Chemistry, 2008, 283 (45), pp.31058-31067 Article dans une revue cea-01997000v1
Increasing the humoral immunogenic properties of the HIV-1 Tat protein using a ligand-stabilizing strategy Alain Lecoq,Gervaise Moine,Laurent Bellanger,Pascal Drevet,Robert Thaiet al. Vaccine, 2008, 26 (21), pp.2615-2626 Article dans une revue cea-01997094v1
Dynamic Combinatorial Self‐Assembly of Cyclophilin hCyp‐18 Ligands through Oxorhenium Coordination Cécile Clavaud,Julien Le Gal,Robert Thai,Mireille Moutiez,Christophe Dugave ChemBioChem, 2008, 9 (11), pp.1823-1829 Article dans une revue cea-01997014v1
Identification of a New Natural Ara h 6 Isoform and of Its Proteolytic Product as Major Allergens in Peanut H. Bernard,L. Mondoulet,M.F. Drumare,E. Paty,P. Scheinmannet al. Journal of Agricultural and Food Chemistry, 2007, 55 (23), pp.9663-9669. ⟨10.1021/jf071424g⟩ Article dans une revue istex cea-02003381v1
Localization and Quantification of Carbon-Centered Radicals on Any Amino Acid of a Protein G. Mousseau,O. Thomas,S. Oppilliart,A. Coirier,A. Salcedo-Sernaet al. Analytical Chemistry, 2007, 79 (14), pp.5444-5448 Article dans une revue cea-02003859v1
Purification and characterization of cassiicolin, the toxin produced by Corynespora cassiicola, causal agent of the leaf fall disease of rubber tree Frédéric de Lamotte,Marie-Pierre Duviau,Christine Sanier,Robert Thai,Joël Poncetet al. Journal of Chromatography B - Analytical Technologies in the Biomedical and Life Sciences, 2007, 849 (1-2), pp.357-362. ⟨10.1016/j.jchromb.2006.10.051⟩ Article dans une revue istex hal-02668494v1
Structural analysis of cassiicolin, a host-selective protein toxin from Corynespora cassiicola Philippe Barthe,Valérie Pujade-Renaud,Frédéric Breton,Daniel Gargani,Robert Thaiet al. Journal of Molecular Biology, 2007, 367 (1), pp.89-101. ⟨10.1016/j.jmb.2006.11.086⟩ Article dans une revue istex hal-02665937v1
The venom of the snake genus Atheris contains a new class of peptides with clusters of histidine and glycine residues. Philippe Favreau,Olivier Cheneval,Laure Menin,Sophie Michalet,Hubert Gaertneret al. Rapid Communications in Mass Spectrometry, 2007, 21 (3), pp.406-12. ⟨10.1002/rcm.2853⟩ Article dans une revue istex hal-00286195v1
Siderophore peptide, a new type of post-translationally modified antibacterial peptide with potent activity. Xavier Thomas,Delphine Destoumieux-Garzón,Jean Peduzzi,Carlos Afonso,Alain Blondet al. Journal of Biological Chemistry, 2004, 279 (27), pp.28233-42. ⟨10.1074/jbc.M400228200⟩ Article dans une revue hal-00016010v1
A synthetic weak neurotoxin binds with low affinity to Torpedo and chicken alpha7 nicotinic acetylcholine receptors. Siew Lay Poh,Gilles Mourier,Robert Thai,Arunmozhiarasi Armugam,Jordi Molgóet al. European Journal of Biochemistry, 2002, 269 (17), pp.4247-56. ⟨10.1046/j.1432-1033.2002.03113.x⟩ Article dans une revue hal-00193986v1
Increasing immunogenicity of antigens fused to Ig-binding proteins by cell surface targeting. M Léonetti,Robert Thai,J Cotton,S Leroy,P Drevetet al. Journal of Immunology, 1998, 160 (8), pp.3820-7 Article dans une revue hal-03038950v1
A particularly labile Asp-Pro bond in the green mamba muscarinic toxin MTX2. Effect of protein conformation on the rate of cleavage Isabelle Ségalas,Robert Thai,Renée Ménez Claudio Vita FEBS Letters, 1995, 371 (2), pp.171-175. ⟨10.1016/0014-5793(95)00844-y⟩ Article dans une revue hal-03038921v1

Communication dans un congrès (1)

Ultra-sensitive detection method with droplet nased microfluidic coupled to MALDI-TOF Kiarach Mesbah,Sarah Bregant,Robert Thai,Vincent Dive,Florent Malloggi 20th International Conference on Miniaturized Systems for Chemistry and Life Sciences (MicroTAS 2016), Oct 2016, Dublin, Ireland Communication dans un congrès cea-02368306v1