rodolphe ALVES DE SOUSA

Publications

Article dans une revue (25)

Inhibition of the Parkinson’s Disease-Related Protein DJ-1 by Endogenous Neurotoxins of the 1,2,3,4-Tetrahydroisoquinoline Family Catherine Laurent,Gabrielle Poncet,Tristan Herskovits,Rodolphe Alves de Sousa,Laurent Le Correet al. ACS Chemical Neuroscience, 2025, 16 (6), pp.1034-1042. ⟨10.1021/acschemneuro.4c00559⟩ Article dans une revue hal-05291792v1
Revisiting the nature and pharmacodynamics of tacrolimus metabolites Rudy Mevizou,Hassan Aouad,François-Ludovic Sauvage,Hélène Arnion,Emilie Pinaultet al. Pharmacological Research, 2024, 209, pp.107438. ⟨10.1016/j.phrs.2024.107438⟩ Article dans une revue hal-05291791v1
Targeted Strategies for Degradation of Key Transmembrane Proteins in Cancer Vehary Sakanyan,Nina Iradyan,Rodolphe Alves de Sousa BioTech, 2023, 12 (3), pp.57. ⟨10.3390/biotech12030057⟩ Article dans une revue hal-04220345v1
Antidepressant efficacy of a selective organic cation transporter blocker in a mouse model of depression Alejandro Orrico-Sanchez,Laetitia Chausset-Boissarie,Rodolphe Alves de Sousa,Basile Coutens,Sara Rezai Aminet al. Molecular Psychiatry, 2020, 25 (6), pp.1245-1259. ⟨10.1038/s41380-019-0548-4⟩ Article dans une revue inserm-03943549v1
Cerpegin-derived furo[3,4-c]pyridine-3,4(1H,5H)-diones enhance cellular response to interferons by de novo pyrimidine biosynthesis inhibition Simon Hayek,Nicolas Pietrancosta,Anna Hovhannisyan,Rodolphe Alves de Sousa,Nassima Bekaddouret al. European Journal of Medicinal Chemistry, 2020, 186, pp.111855. ⟨10.1016/j.ejmech.2019.111855⟩ Article dans une revue hal-02372490v1
Targeting Degradation of EGFR through the Allosteric Site Leads to Cancer Cell Detachment-Promoted Death Melkon Iradyan,Nina Iradyan,Philippe Hulin,Artur Hambardzumyan,Aram Gyulkhandanyanet al. Cancers, 2019, 11 (8), pp.1094. ⟨10.3390/cancers11081094⟩ Article dans une revue hal-02321259v2
Identification of Primary Natural Killer Cell Modulators by Chemical Library Screening with a Luciferase-Based Functional Assay Simon Hayek,Nassima Bekaddour,Laurie Besson,Rodolphe Alves de Sousa,Nicolas Pietrancostaet al. Slas Discovery, 2018, 24 (1), pp.25-37. ⟨10.1177/2472555218797078⟩ Article dans une revue hal-02324386v1
SELECTIVE N-, S-ALKYLATION OF 4-ALLYL-3-[2-(4-ALKOXYPHENYL)- QUINOLIN-4-YL]-4,5-DIHYDRO-1H-1,2,4-TRIAZOLE-5-THIONES WITH SUBSTITUTED BENZYLCHLORIDES. SYNTHESIS, DOCKING ANALYSIS AND СYTOTOXIC ACTION Rodolphe Alves de Sousa,М Ирадян,А Амбарцумян,Г Паносян,Р Тамазянet al. Chemical Journal of Armenia, 2018 Article dans une revue hal-03652521v1
Microspectrofluorimetry to dissect the permeation of ceftazidime in Gram-negative bacteria Anas Allam,Laure Maigre,Julia Vergalli,Estelle Dumont,Bertrand Cinquinet al. Scientific Reports, 2017, 7 (1), pp.986. ⟨10.1038/s41598-017-00945-8⟩ Article dans une revue hal-01831783v1
Microspectrofluorimetry to dissect the permeation of ceftazidime in Gram-negative bacteria Anas Allam,Laure Maigre,Julia Vergalli,Estelle Dumont,Bertrand Cinquinet al. Scientific Reports, 2017, 7 (1), pp.986. ⟨10.1038/s41598-017-00945-8⟩ Article dans une revue hal-03652530v1
New amphiphilic neamine conjugates bearing a metal binding motif active against MDR E. aerogenes Gram-negative bacteria Anas Allam,Laure Maigre,Rodolphe Alves de Sousa,Estelle Dumont,Julia Vergalliet al. European Journal of Medicinal Chemistry, 2017, 127, pp.748-756. ⟨10.1016/j.ejmech.2016.10.054⟩ Article dans une revue hal-03652533v1
Erratum: Corrigendum: A unique peptide deformylase platform to rationally design and challenge novel active compounds Sonia Fieulaine,Rodolphe Alves de Sousa,Laure Maigre,Karim Hamiche,Mickael Alimiet al. Scientific Reports, 2017, 7 (1), pp.39365. ⟨10.1038/srep39365⟩ Article dans une revue hal-03652528v1
A unique peptide deformylase platform to rationally design and challenge novel active compounds Sonia Fieulaine,Rodolphe Alves de Sousa,Laure Maigre,Karim Hamiche,Mickael Alimiet al. Scientific Reports, 2016, 6 (1), pp.35429. ⟨10.1038/srep35429⟩ Article dans une revue hal-03652534v1
Activation of EGFR by small compounds through coupling the generation of hydrogen peroxide to stable dimerization of Cu/Zn SOD1 Vehary Sakanyan,Philippe Hulin,Rodolphe Alves de Sousa,Viviane Silva,Artur Hambardzumyanet al. Scientific Reports, 2016, 6 (1), pp.21088. ⟨10.1038/srep21088⟩ Article dans une revue hal-03652537v1
Straightforward Detection of Reactive Compound Binding to Multiple Proteins in Cancer Cells: Towards a Better Understanding of Electrophilic Stress Rodolphe Alves de Sousa,Vehary Sakanyan Annals of Clinical & Experimental Metabolism, 2016 Article dans une revue hal-03662587v1
A unique peptide deformylase platform to rationally design and challenge novel active compounds Sonia Fieulaine,Rodolphe Alves de Sousa,Laure Maigre,Karim Hamiche,Mickael Alimiet al. Scientific Reports, 2016, 6, pp.35429. ⟨10.1038/srep35429⟩ Article dans une revue hal-01412212v1
New Peptides with Metal Binding Abilities and Their Use as Drug Carriers Anas Allam,Laure Maigre,Mickael Alimi,Rodolphe Alves de Sousa,Assia Hessaniet al. Bioconjugate Chemistry, 2014, 25 (10), pp.1811-1819. ⟨10.1021/bc500317u⟩ Article dans une revue hal-03652539v1
New peptide deformylase inhibitors and cooperative interaction: a combination to improve antibacterial activity Emilie Goemaere,Armelle Melet,Valéry Larue,Aurélie Lieutaud,Rodolphe Alves de Sousaet al. Journal of Antimicrobial Chemotherapy, 2012, 67 (6), pp.1392-1400. ⟨10.1093/jac/dks058⟩ Article dans une revue hal-03652545v1
New peptide deformylase inhibitors and cooperative interaction: a combination to improve antibacterial activity. Emilie Goemaere,Armelle Melet,Valéry Larue,Aurélie Lieutaud,Rodolphe Alves de Sousaet al. Journal of Antimicrobial Chemotherapy, 2012, 67 (6), pp.1392-400. ⟨10.1093/jac/dks058⟩ Article dans une revue hal-00851369v1
Bis-β-sulfanylethylester and cyclic disulfide-S-oxides as precursors of bifunctionalized anionic derivatives with two oxidized sulfurs Rodolphe Alves de Sousa,Isabelle Artaud Tetrahedron, 2008, 64 (9), pp.2198-2206. ⟨10.1016/j.tet.2007.12.023⟩ Article dans une revue istex hal-03652546v1
Synthesis of cyclic mono- and bis-disulfides and their selective conversion to mono- and bis-thiosulfinates Emilie Bourlès,Rodolphe Alves de Sousa,Erwan Galardon,Mohamed Selkti,Alain Tomaset al. Tetrahedron, 2007, 63 (11), pp.2466-2471. ⟨10.1016/j.tet.2007.01.002⟩ Article dans une revue istex hal-03652551v1
Discovery and Refinement of a New Structural Class of Potent Peptide Deformylase Inhibitors Adrien Boularot,Carmela Giglione,Sylvain Petit,Yann Duroc,Rodolphe Alves de Sousaet al. Journal of Medicinal Chemistry, 2007, 50 (1), pp.10-20. ⟨10.1021/jm060910c⟩ Article dans une revue hal-03652549v1
Discovery and Refinement of a New Structural Class of Potent Peptide Deformylase Inhibitors. Adrien Boularot,Carmela Giglione,Sylvain Petit,Yann Duroc,Rodolphe Alves de Sousaet al. Journal of Medicinal Chemistry, 2007, 50 (1), pp.10-20. ⟨10.1021/jm060910c⟩ Article dans une revue hal-00123257v1
Oxidation of Zn(N2S2) complexes to disulfonates: relevance to zinc-finger oxidation under oxidative stress Rodolphe Alves de Sousa,Erwan Galardon,Mathieu Rat,Michel Giorgi,Isabelle Artaud Journal of Inorganic Biochemistry, 2005, 99 (3), pp.690-697. ⟨10.1016/j.jinorgbio.2004.11.019⟩ Article dans une revue istex hal-03652562v1
Direct Synthesis of a Thiolato-S and Sulfinato-S CoIII Complex Related to the Active Site of Nitrile Hydratase: A Pathway to the Post-Translational Oxidation of the Protein Emilie Bourles,Rodolphe Alves de Sousa,Erwan Galardon,Michel Giorgi,Isabelle Artaud Angewandte Chemie International Edition, 2005, 44 (38), pp.6162-6165. ⟨10.1002/anie.200500814⟩ Article dans une revue istex hal-03652558v1

Pré-publication, Document de travail (1)

HTRF-based identification of small molecules targeting SARS-CoV-2 E protein interaction with ZO-1 PDZ2 Flavio Alvarez,Florence Larrous,Ariel Mechaly,Benjamin Bardiaux,Quentin Gooret al. 2025 Pré-publication, Document de travail pasteur-05261353v1