Claire ROME Enseignant-chercheurUniversité Grenoble Alpes

Identifiants chercheurs

IdHAL :

rome-claire

ORCID :

0000-0002-3573-0543

IdRef :

076605108

Présentation

Mon travail est focalisé sur l’utilisation de techniques innovantes d'acquisition et d'analyse IRM pour caractériser le microenvironnement cérébral et étudier les effets de thérapies, principalement cellulaires, dans des pathologies comme les tumeurs cérébrales et l'AVC.

Publications

Article dans une revue (38)

A self-healing radiopaque hyaluronic acid hydrogel as a new injectable biomaterial for precision medicine in osteoarthritis Moustoifa Said,Clément Tavakoli,Chloé Dumot,Karine Toupet,Cécile Olivieret al. Theranostics, 2025, 15 (9), pp.4054-4073. ⟨10.7150/thno.104551⟩ Article dans une revue hal-05234760v1
A T 1 MRI detectable hyaluronic acid hydrogel for in vivo tracking after intracerebral injection in stroke Moustoifa Said,Jing Jing,Olivier Montigon,Nora Collomb,Frédérique Vossieret al. Journal of materials chemistry‎ B, 2025, 13 (13), pp.4103-4117. ⟨10.1039/d4tb02722a⟩ Article dans une revue inserm-05022548v1
Junctional adhesion molecule C limits glioblastoma stem-like cell invasion by regulating integrin adhesion at the endothelial interface Sara Rosińska,Gwennan André-Grégoire,Mathilde Kerhervé,Kilian Trillet,Lais Brigliadori Fugioet al. Cell Reports, 2025, 44 (9), pp.116194. ⟨10.1016/j.celrep.2025.116194⟩ Article dans une revue hal-05241345v1
FUS-mediated BBB opening leads to transient perfusion decrease and inflammation without acute or chronic brain lesion Sébastien Rigollet,Claire Rome,Thomas Ador,Erik Dumont,Chantal Pichonet al. Theranostics, 2024, 14 (10), pp.4147-4160. ⟨10.7150/thno.96721⟩ Article dans une revue hal-04634511v1
Cerebral oxidative stress, inflammation and apoptosis induced by intermittent hypoxia: a systematic review and meta-analysis of rodent data Bayan El Amine,Joey Fournier,Mélanie Minoves,Sébastien Baillieul,Frédéric Rocheet al. European Respiratory Review, 2024, 33 (174), pp.240162. ⟨10.1183/16000617.0162-2024⟩ Article dans une revue hal-04757190v1
Microbeam Radiation Therapy Opens a Several Days’ Vessel Permeability Window for Small Molecules in Brain Tumor Vessels Marine Potez,Claire Rome,Benjamin Lemasson,Pierre Heemeryck,Jean Albert Laissueet al. International Journal of Radiation Oncology, Biology, Physics, 2024, Online ahead of print. ⟨10.1016/j.ijrobp.2024.02.007⟩ Article dans une revue hal-04647258v1
Cell Therapy and Functional Recovery of Stroke Olivier Detante,Loic Legris,Anaick Moisan,Claire Rome Neuroscience, 2024, 550, pp.79-88. ⟨10.1016/j.neuroscience.2023.11.027⟩ Article dans une revue hal-04697228v1
Apnée du sommeil post-AVC : effet de l’hypoxie intermittente sur la récupération cérébrovasculaire Bayan El Amine,Anne Briancon-Marjollet,Claire Rome,Benjamin Lemasson,Florence Fauvelleet al. Médecine du sommeil, 2024, 21 (1), pp.4. ⟨10.1016/j.msom.2023.12.002⟩ Article dans une revue inserm-04850155v1
Microbeam Radiation Therapy Opens a Several Days’ Vessel Permeability Window for Small Molecules in Brain Tumor Vessels Marine Potez,Claire Rome,Benjamin Lemasson,Pierre Heemeryck,Jean Albert Laissueet al. International Journal of Radiation Oncology, Biology, Physics, 2024, 119 (5), pp.1506-1516. ⟨10.1016/j.ijrobp.2024.02.007⟩ Article dans une revue hal-04825697v1
Neurofunctional and neuroimaging readouts for designing a preclinical stem-cell therapy trial in experimental stroke Chloé Dumot,Chrystelle Po,Lucille Capin,Violaine Hubert,Elodie Onget al. Scientific Reports, 2022, 12, pp.4700. ⟨10.1038/s41598-022-08713-z⟩ Article dans une revue hal-03451443v2
Injectable Self-Healing Hydrogels Based on Boronate Ester Formation between Hyaluronic Acid Partners Modified with Benzoxaborin Derivatives and Saccharides Tamiris Figueiredo,Jing Jing,Isabelle Jeacomine,Johan Olsson,Thibaud Gerfaudet al. Biomacromolecules, 2020, 21 (1), pp.230-239. ⟨10.1021/acs.biomac.9b01128⟩ Article dans une revue hal-03794022v1
Synchrotron X-Ray Boost Delivered by Microbeam Radiation Therapy After Conventional X-Ray Therapy Fractionated in Time Improves F98 Glioma Control Marine Potez,Audrey Bouchet,Mélanie Flaender,Claire Rome,Nora Collombet al. International Journal of Radiation Oncology, Biology, Physics, 2020, 107 (2), pp.360-369. ⟨10.1016/j.ijrobp.2020.02.023⟩ Article dans une revue hal-05142241v1
Synchrotron X-Ray Boost Delivered by Microbeam Radiation Therapy After Conventional X-Ray Therapy Fractionated in Time Improves F98 Glioma Control Marine Potez,Audrey Bouchet,Mélanie Flaender,Claire Rome,Nora Collombet al. International Journal of Radiation Oncology, Biology, Physics, 2020, 107 (2), pp.360-369. ⟨10.1016/j.ijrobp.2020.02.023⟩ Article dans une revue hal-03326708v1
Near-Infrared Optical Imaging of Nucleic Acid Nanocarriers In Vivo Claire Rome,Julien Gravier,Marie Morille,Gilles Divita,Anne-Laure Bolcato-Belleminet al. Methods in Molecular Biology, 2019, Nanotechnology for Nucleic Acid Delivery Methods and Protocols, 1943, pp.347-363. ⟨10.1007/978-1-4939-9092-4_23⟩ Article dans une revue (article de synthèse) hal-04697267v1
Dynamical properties of water in living cells Irina Piazza,Antonio Cupane,Emmanuel Barbier,Claire Rome,Nora Collombet al. Frontiers of Physics, 2018, 13 (1), pp.138301. ⟨10.1007/s11467-017-0731-5⟩ Article dans une revue inserm-05300265v1
Permeability of Brain Tumor Vessels Induced by Uniform or Spatially Microfractionated Synchrotron Radiation Therapies Audrey Bouchet,Marine Potez,Nicolas Coquery,Claire Rome,Benjamin Lemassonet al. International Journal of Radiation Oncology, Biology, Physics, 2017, 98 (5), pp.1174-1182. ⟨10.1016/j.ijrobp.2017.03.025⟩ Article dans une revue hal-05142260v1
Permeability of Brain Tumor Vessels Induced by Uniform or Spatially Microfractionated Synchrotron Radiation Therapies Audrey Bouchet,Marine Potez,Nicolas Coquery,Claire Rome,Benjamin Lemassonet al. International Journal of Radiation Oncology, Biology, Physics, 2017, 98 (5), pp.1174-1182. ⟨10.1016/j.ijrobp.2017.03.025⟩ Article dans une revue (data paper) hal-04697277v1
Intravenous Injection of Clinical Grade Human MSCs after Experimental Stroke: Functional Benefit and Microvascular Effect Anaïck Moisan,Isabelle Favre,Claire Rome,Florence de Fraipont,Emmanuelle Grillonet al. Cell Transplantation, 2016, 25 (12), pp.2157-2171. ⟨10.3727/096368916X691132⟩ Article dans une revue (data paper) hal-04697292v1
Biomaterial Applications in Cell‐Based Therapy in Experimental Stroke Ligia S B Boisserand,Tomonobu Kodama,Jérémie Papassin,Rachel Auzely,Anaïck Moisanet al. Stem Cells International, 2016, 2016 (1), pp.6810562. ⟨10.1155/2016/6810562⟩ Article dans une revue (article de synthèse) hal-04697287v1
IPP51, a chalcone acting as a microtubule inhibitor with in vivo antitumor activity against bladder carcinoma. Véronique Martel-Frachet,Michelle Keramidas,Alessandra Nurisso,Salvatore Debonis,Claire Romeet al. Oncotarget, 2015, 6 (16), pp.14669-86. ⟨10.18632/oncotarget.4144⟩ Article dans une revue hal-01234550v1
Microvascular Plasticity After Experimental Stroke: A Molecular and MRI Study Anaick Moisan,Isabelle Favre,Claire Rome,Emmanuelle Grillon,Bernadette Naegeleet al. Cerebrovascular Diseases, 2014, 38 (5), pp.344-353. ⟨10.1159/000368597⟩ Article dans une revue (data paper) hal-04697339v1
Synchrotron microbeam radiation therapy induces hypoxia in intracerebral gliosarcoma but not in the normal brain. Audrey Bouchet,Benjamin Lemasson,Thomas Christen,Marine Potez,Claire Romeet al. Radiotherapy & Oncology, 2013, 108 (1), pp.143-8. ⟨10.1016/j.radonc.2013.05.013⟩ Article dans une revue istex inserm-00855558v1
The dual effect of MSCs on tumour growth and tumour angiogenesis. Michelle Kéramidas,Florence de Fraipont,Anastassia Karageorgis,Anaïck Moisan,Virginie Persoonset al. Stem Cell Research and Therapy, 2013, 4 (2), pp.41. ⟨10.1186/scrt195⟩ Article dans une revue inserm-00822004v1
Synchrotron microbeam radiation therapy induces hypoxia in intracerebral gliosarcoma but not in the normal brain Audrey Bouchet,Benjamin Lemasson,Thomas Christen,Marine Potez,Claire Romeet al. Radiotherapy & Oncology, 2013, 108 (1), pp.143-148. ⟨10.1016/j.radonc.2013.05.013⟩ Article dans une revue istex hal-05142308v1
Identification of a novel BET bromodomain inhibitor-sensitive, gene regulatory circuit that controls Rituximab response and tumour growth in aggressive lymphoid cancers. Anouk Emadali,Sophie Rousseaux,Juliana Bruder-Costa,Claire Rome,Samuel Duleyet al. EMBO Molecular Medicine, 2013, 5 (8), pp.1180-95. ⟨10.1002/emmm.201202034⟩ Article dans une revue inserm-00852222v1
CCM1–ICAP-1 complex controls β1 integrin–dependent endothelial contractility and fibronectin remodeling Eva Faurobert,Claire Rome,Justyna Lisowska,Sandra Manet-Dupé,Gwénola Bouldayet al. Journal of Cell Biology, 2013, 202 (3), pp.545 - 561. ⟨10.1083/jcb.201303044⟩ Article dans une revue (data paper) hal-04697332v1
Distribution and radiosensitizing effect of cholesterol-coupled Dbait molecule in rat model of glioblastoma. Nicolas Coquery,Nicolas Pannetier,Régine Farion,Aurélie Herbette,Leire Azurmendiet al. PLoS ONE, 2012, 7 (7), pp.e40567. ⟨10.1371/journal.pone.0040567⟩ Article dans une revue inserm-00874418v1
The Natural Cell-Penetrating Peptide Crotamine Targets Tumor Tissue in Vivo and Triggers a Lethal Calcium-Dependent Pathway in Cultured Cells Fabio Nascimento,Lucie Sancey,Alexandre Pereira,Claire Rome,Vitor Oliveiraet al. Molecular Pharmaceutics, 2011, 9 (2), pp.211-221. ⟨10.1021/mp2000605⟩ Article dans une revue (data paper) hal-04697356v1
Drug development in oncology assisted by noninvasive optical imaging. Lucie Sancey,Sandrine Dufort,Véronique Josserand,Michelle Keramidas,Christian A. Righiniet al. International Journal of Pharmaceutics, 2009, 379 (2), pp.309-16. ⟨10.1016/j.ijpharm.2009.05.034⟩ Article dans une revue inserm-00390608v1
The role of ultrasound and magnetic resonance in local drug delivery. Roel Deckers,Claire Rome,Chrit T. W. Moonen Journal of Magnetic Resonance Imaging, 2008, 27 (2), pp.400-9. ⟨10.1002/jmri.21272⟩ Article dans une revue istex inserm-00332078v1
The use of ultrasound in transfection and transgene expression. Claire Rome,Roel Deckers,Chrit Moonen Handb Exp Pharmacol, 2008, 2 (185 Pt 2), pp.225-43. ⟨10.1007/978-3-540-77496-9_9⟩ Article dans une revue inserm-00332076v1
Gene expression and gene therapy imaging. Claire Rome,Franck Couillaud,Chrit T. W. Moonen European Radiology, 2007, 17 (2), pp.305-19. ⟨10.1007/s00330-006-0378-z⟩ Article dans une revue istex inserm-00176689v1
MMP-7 (matrilysin) expression in human brain tumors. Claire Rome,Josette Arsaut,Caroline Taris,Franck Couillaud,Hugues Loiseau Molecular Carcinogenesis, 2007, 46 (6), pp.446-52. ⟨10.1002/mc.20293⟩ Article dans une revue istex inserm-00176688v1
Diversity of contactin mRNA in human brain tumors. Claire Rome,Hugues Loiseau,Josette Arsaut,Valérie Roullot,Franck Couillaud Molecular Carcinogenesis, 2006, 45 (10), pp.774-85. ⟨10.1002/mc.20244⟩ Article dans une revue istex inserm-00176690v1
Spatial and temporal control of expression of therapeutic genes using heat shock protein promoters Claire Rome,Franck Couillaud,Chrit T.W. Moonen Methods, 2005, 35 (2), pp.188-198. ⟨10.1016/j.ymeth.2004.08.011⟩ Article dans une revue istex hal-05300237v1
Polymorphism of the untranslated regions of the F3/contactin mRNA in the rat nervous system Claire Rome,Valérie Roullot,Franck Couillaud Molecular Brain Research, 2005, 139 (1), pp.184-191. ⟨10.1016/j.molbrainres.2005.05.012⟩ Article dans une revue istex hal-05300238v1
Substance P mobilizes intracellular calcium and activates a nonselective cation conductance in rat spiral ganglion neurons Ken Ito,Claire Rome,Yohan Bouleau,Didier Dulon European Journal of Neuroscience, 2002, 16 (11), pp.2095-2102. ⟨10.1046/j.1460-9568.2002.02292.x⟩ Article dans une revue istex hal-05300241v1
Muscarinic receptor-mediated calcium signaling in spiral ganglion neurons of the mammalian cochlea Claire Rome,Defeng Luo,Didier Dulon Brain Research, 1999, 846 (2), pp.196-203. ⟨10.1016/s0006-8993(99)02034-x⟩ Article dans une revue istex hal-05300245v1

Communication dans un congrès (12)

Longitudinal imaging with multicolour CT provides a surrogate marker of response to treatment with a novel iodine-labelled hydrogel in a murine model of osteoarthritis Clément Tavakoli,Moustoifa Said,Alexia Gilles,Cecile Olivier,Yuxi Clara Donget al. 20th annual European Molecular Imaging Meeting (EMIM), 2025, Bilbao, Spain Communication dans un congrès hal-04890994v1
In vivo monitoring of stem cells and their encapsulating scaffold using dual-contrast agent labelling and multicolour CT: application in a murine model of osteoarthritis Clément Tavakoli,Moustoifa Said,Cécile Olivier,Alexia Gilles,Yuxi Clara Donget al. Contrast Media Research Symposium, 2024, Oslo (Norway), Norway Communication dans un congrès hal-04890788v1
In vivo monitoring of hydrogel-embedded stem cells: combination of Synchrotron X-ray phase-contrast and multi-spectral imaging applied to osteoarthritis mice models. Clément Tavakoli,Moustoifa Said,Karine Toupet,Johoon Kim,Bertrand Favieret al. 18th annual European Molecular Imaging Meeting (EMIM), 2023, Salzburg (Austria), Austria Communication dans un congrès hal-04890743v1
Long term in vivo magnetic resonance imaging of injectable self-healing hydrogels based on hyaluronic acid for cell therapy Moustoifa Said,Olivier Montigon,Nora Collomb,Benjamin Lemasson,Emmanuel L Barbieret al. 18th European Molecular Imaging Meeting (EMIM), Mar 2023, Salzburg, Austria Communication dans un congrès hal-04896446v1
Post Stroke Sleep Apnea: Effect of Intermittent Hypoxia on Cerebrovascular Recovery Bayan El Amine,Benjamin L Lemasson,Florence Fauvelle,Natacha Collomb,Emeline Lemariéet al. Congrès du Sommeil, 2023, Lille, France Communication dans un congrès hal-04849430v1
Post Stroke Sleep Apnea: Effect of Intermittent Hypoxia on Cerebrovascular Recovery. Bayan El Amine,Benjamin L Lemasson,Florence Fauvelle,N Collomb,Emeline Mercieret al. Congrès du Sommeil, Nov 2023, Lille, France Communication dans un congrès hal-04892234v1
Monitoring the fate of stem cells and their encapsulating hydrogel in mice knees using Synchrotron K-edge subtraction computed tomography Clément Tavakoli,Moustoifa Said,Karine Toupet,Johoon Kim,Bertrand Favieret al. 17th annual meeting European Molecular Imaging Meeting (EMIM), 2022, Thessaloniki, Greece Communication dans un congrès hal-04890848v1
An iodine labeled injectable hyaluronic acid hydrogel for an in vivo bicolor x-ray monitoring of a biomimetic scaffold in brain regeneration cell therapy Moustoifa Said,Clément Takavoli,Chloé Dumot,Nora Collomb,Anaïck Moisanet al. 32nd Annual Conference of the European Society of Biomaterials 2022, European Society of Biomaterials, Sep 2022, Bordeaux, France Communication dans un congrès hal-04850142v1
Post Stroke Sleep Apnea: Effect of Intermittent Hypoxia on Cerebrovascular Recovery Bayan El Amine,Benjamin L Lemasson,Florence Fauvelle,M.N. Collomb,Emeline Lemariéet al. Journée de la Recherche Médicale, Jun 2022, Grenoble, France Communication dans un congrès hal-04849280v1
Monitoring the fate of stem cells and encapsulating hydrogel intraarticularly injected in mice knees using Synchrotron K-edge subtraction computed tomography Clément Tavakoli,Moustoifa Said,Karine Toupet,Johoon Kim,Bertrand Favieret al. SPIE Optics and Photonics, 2022, San Diego (California), United States Communication dans un congrès hal-04890813v1
An iodine-labelled hyaluronic acid-based hydrogel : a radiopaque biopolymer to monitor the fate of bioscaffold in cell therapy applications Moustoifa Said,Clément Takavoli,Chloé Dumot,Nora Collomb,Anaïck Moisanet al. 4th BIOMAT congress 2021, Oct 2021, Bourg Saint Maurice, France Communication dans un congrès hal-04889886v1
Synchrotron X-ray boost delivered by Microbeam Radiation Therapy improves glioma control after conventional fractionated X-ray therapy Audrey Bouchet,Marine Potez,Mélanie Flaender,Laura Schaad,Claire Romeet al. Medical Applications of Synchrotron Radiation MASR 2015, Oct 2015, Villard de Lans, France Communication dans un congrès hal-01236285v1

Poster de conférence (2)

Ultrasound and Cationic Microbubble Assisted Gene Delivery in the Brain for Fragile X Syndrome Therapy C. Delehedde,V. de Concini,R. Clémençon,C. Si Ahmed,Sandra Mêmeet al. French Society of Nanomedicine and C’Nano Joint conference, Dec 2019, Dijon, France Poster de conférence hal-03668578v1
Impact of focused ultrasound on cerebral blood flow V. Stupar,Anthony Delalande,N. Collomb,C. Rome,E. And Barbier Joint Annual Meeting ISMRM-ESMRMB, Jun 2018, Paris, France Poster de conférence hal-03668579v1

Chapitre d'ouvrage (2)

Near-infrared optical imaging of nucleic acid nanocarriers in vivo. Claire Rome,Julien Gravier,Marie Morille,Gilles Divita,Anne-Laure Bolcato-Belleminet al. Nanotechnology for Nucleic Acid Delivery, 948, Humana Press, pp.49-65, 2013, ⟨10.1007/978-1-62703-140-0_5⟩ Chapitre d'ouvrage inserm-00874399v1
Near-Infrared Optical Imaging of Nucleic Acid Nanocarriers In Vivo Claire Rome,Julien Gravier,Marie Morille,Gilles Divita,Anne-Laure Bolcato-Belleminet al. Near-Infrared Optical Imaging of Nucleic Acid Nanocarriers In Vivo, pp.49-65, 2013, ⟨10.1007/978-1-62703-140-0_5⟩ Chapitre d'ouvrage hal-03212203v1

Pré-publication, Document de travail (1)

A novel injectable radiopaque hydrogel with potent properties for multicolor CT imaging in the context of brain and cartilage regenerative therapy Moustoifa Said,Clément Tavakoli,Chloé Dumot,Karine Toupet,Yuxi Clara Donget al. 2023 Pré-publication, Document de travail hal-04126192v1

HDR (1)

Potentialisation des Thérapies cellulaires des accidents vasculaires cérébraux utilisant des cellules souches/progénitrices et des biomatériaux en recherche pré-clinique Claire Rome Sciences du Vivant [q-bio]. Université Grenoble - Alpes, 2021 HDR tel-04767124v1