ronan bureau

Documents

Présentation

Publications

Mapping ligands for MT1/MT2 and 5-HT2C receptors: Chemotypes, SAR, and polypharmacology

Alban Lepailleur , Damien Geslin , Johanna Giovannini , Bertrand Cuissart , Jean-Luc Lamotte et al.

Drug Discovery Today, 2026, 31 (2), pp.104600. ⟨10.1016/j.drudis.2026.104600⟩

Article dans une revue hal-05474436v1

Pharmacophore-driven kinase profiling applied to the PKIS2 chemogenomic dataset

Ronan Bureau , Jean-Luc Lamotte , Bertrand Cuissart , Alban Lepailleur

Scientific Reports, 2026, 16 (1), pp.12083. ⟨10.1038/s41598-026-42945-7⟩

Article dans une revue hal-05618935v1

Navigating pharmacophore space to identify activity discontinuities: a case study with BCR‐ABL

Maroua Lejmi , Damien Geslin , Ronan Bureau , Bertrand Cuissart , Ilef Ben Slima et al.

Molecular Informatics, 2024, GREYC, 43 (8), pp.e202400050. ⟨10.1002/minf.202400050⟩

Article dans une revue hal-04667697v1

Towards a partial order graph for interactive pharmacophore exploration: extraction of pharmacophores activity delta

Etienne Lehembre , Johanna Giovannini , Damien Geslin , Alban Lepailleur , Jean-Luc Lamotte et al.

Journal of Cheminformatics, 2023, 15 (1), pp.116. ⟨10.1186/s13321-023-00782-0⟩

Article dans une revue hal-04313812v1

Deciphering a Pharmacophore Network: A Case Study Using BCR-ABL Data

Damien Geslin , Alban Lepailleur , Jean-Luc Manguin , Nhat-Vinh Vo , Jean-Luc Lamotte et al.

Journal of Chemical Information and Modeling, 2022, 62 (3), pp.678-691. ⟨10.1021/acs.jcim.1c00427⟩

Article dans une revue hal-03658524v1

Cryptic Pockets Repository through Pocket Dynamics Tracking and Metadynamics on Essential Dynamics Space: Applications to Mcl-1

Mohammed Benabderrahmane , Ronan Bureau , Anne Sophie Voisin-Chiret , Jana Sopkova-de Oliveira Santos

Journal of Chemical Information and Modeling, 2021, 61 (11), pp.5581-5588. ⟨10.1021/acs.jcim.1c00660⟩

Article dans une revue hal-03961772v1

Synthesis of 3,3-Diarylazetidines by Calcium(II)-Catalyzed Friedel–Crafts Reaction of Azetidinols with Unexpected Cbz Enhanced Reactivity

Camille Denis , Maryne Dubois , Anne-Sophie Voisin-Chiret , Ronan Bureau , Chulho Choi et al.

Organic Letters, 2019, 21 (1), pp.300-304. ⟨10.1021/acs.orglett.8b03745⟩

Article dans une revue hal-02043642v1

Joint effects of nine antidepressants on Raphidocelis subcapitata and Skeletonema marinoi : A matter of amine functional groups

Laetitia Minguez , Ronan Bureau , Marie-Pierre Halm-Lemeille

Aquatic Toxicology, 2018, 196, pp.117-123. ⟨10.1016/j.aquatox.2018.01.015⟩

Article dans une revue hal-01800709v1

Structure-guided design of pyridoclax derivatives based on Noxa / Mcl-1 interaction mode

Siham Hedir , Marcella de Giorgi , Jade Fogha , Martina de Pascale , Louis-Bastien Weiswald et al.

European Journal of Medicinal Chemistry, 2018, 159, pp.357-380. ⟨10.1016/j.ejmech.2018.10.003⟩

Article dans une revue inserm-01980723v1

The Pharmacophore Network: A Computational Method for Exploring Structure–Activity Relationships from a Large Chemical Data Set

Jean-Philippe Metivier , Bertrand Cuissart , Ronan Bureau , Alban Lepailleur

Journal of Medicinal Chemistry, 2018, 61 (8), pp.3551-3564. ⟨10.1021/acs.jmedchem.7b01890⟩

Article dans une revue hal-02043686v1

A Computational Selection of Metabolite Biomarkers Using Emerging Pattern Mining: A Case Study in Human Hepatocellular Carcinoma

Guillaume Poezevara , Sylvain Lozano , Bertrand Cuissart , Ronan Bureau , Pierre Bureau et al.

Journal of Proteome Research, 2017, 16 (6), pp.2240-2249. ⟨10.1021/acs.jproteome.7b00054⟩

Article dans une revue hal-01576908v1

The Arg-Phe-amide peptide 26RFa/glutamine RF-amide peptide and its receptor: IUPHAR Review 24

Jérôme Leprince , Didier Bagnol , Ronan Bureau , Shoji Fukusumi , Riccarda Granata et al.

British Journal of Pharmacology, 2017, 174 (20), pp.3573-3607. ⟨10.1111/bph.13907⟩

Article dans une revue hal-01972620v1

Non a Priori Automatic Discovery of 3D Chemical Patterns: Application to Mutagenicity

Julien Rabatel , Fannes Thomas , Alban Lepailleur , Jérémie Le Goff , Bruno Crémilleux et al.

Molecular Informatics, 2017, Special Issue: Chemoinformatics in France, 36 (10), ⟨10.1002/minf.201700022⟩

Article dans une revue hal-01576894v1

Conformation and Dynamics of Human Urotensin II and Urotensin Related Peptide in Aqueous Solution

Elke Haensele , Nawel Mele , Marija Miljak , Christopher Read , David Whitley et al.

Journal of Chemical Information and Modeling, 2017, 57 (2), pp.298-310. ⟨10.1021/acs.jcim.6b00706⟩

Article dans une revue hal-02043740v1

Toward Understanding Mcl-1 Promiscuous and Specific Binding Mode

Jade Fogha , Bogdan Marekha , Marcella de Giorgi , Anne-Sophie Voisin-Chiret , Sylvain Rault et al.

Journal of Chemical Information and Modeling, 2017, 57 (11), pp.2885-2895. ⟨10.1021/acs.jcim.7b00396⟩

Article dans une revue hal-02043710v1

Acute toxicities of pharmaceuticals toward green algae. mode of action, biopharmaceutical drug disposition classification system and quantile regression models

Villain Jonathan , Latitia Minguez , Marie-Pierre Halm-Lemeille , Gilles Durrieu , Ronan Bureau

Ecotoxicology and Environmental Safety, 2016, 124, pp.337-343. ⟨10.1016/j.ecoenv.2015.11.009⟩

Article dans une revue istex hal-01262279v1

A Three-Site Mechanism for Agonist/Antagonist Selective Binding to Vasopressin Receptors

Noureldin Saleh , Giorgio Saladino , Francesco Gervasio , Elke Haensele , Lee Banting et al.

Angewandte Chemie International Edition, 2016, 55 (28), pp.8008-8012. ⟨10.1002/ange.201602729⟩

Article dans une revue hal-02043755v1

Protective effects of caffeic acid against hypothalamic neuropeptides alterations induced by malathion in rat

Raja Rezg , Bessem Mornagui , Jana Sopkova-de Oliveira Santos , Fabienne Dulin , Saloua El-Fazaa et al.

Environmental Science and Pollution Research, 2015, 22 (8), pp.6198-6207. ⟨10.1007/s11356-014-3824-5⟩

Article dans une revue hal-02045966v1

Discovering structural alerts for mutagenicity using stable emerging molecular patterns

Jean-Philippe Metivier , Alban Lepailleur , Aleksey Buzmakov , Guillaume Poezevara , Bruno Crémilleux et al.

Journal of Chemical Information and Modeling, 2015, 55 (5), pp.925-940. ⟨10.1021/ci500611v⟩

Article dans une revue hal-01186716v1

First Evidence That Oligopyridines, α-Helix Foldamers, Inhibit Mcl-1 and Sensitize Ovarian Carcinoma Cells to Bcl-x L -Targeting Strategies

Céline Gloaguen , Anne-Sophie Voisin-Chiret , Jana Sopkova-de Oliveira Santos , Jade Fogha , Fabien Gautier et al.

Journal of Medicinal Chemistry, 2015, 58 (4), pp.1644-1668. ⟨10.1021/jm500672y⟩

Article dans une revue hal-02043913v1

Acute toxicity of 8 antidepressants: What are their modes of action?

Laetitia Minguez , Emilie Farcy , Céline Ballandonne , Alban Lepailleur , Antoine Serpentini et al.

Chemosphere, 2014, 108, pp.314 - 319. ⟨10.1016/j.chemosphere.2014.01.057⟩

Article dans une revue istex hal-01800717v1

Dual Histamine H3R/Serotonin 5-HT4R Ligands with Antiamnesic Properties: Pharmacophore-Based Virtual Screening and Polypharmacology.

Alban Lepailleur , Thomas Freret , Stéphane Lemaître , Michel Boulouard , François Dauphin et al.

Journal of Chemical Information and Modeling, 2014, 54 (6), pp.1773-1784. ⟨10.1021/ci500157n⟩

Article dans une revue hal-01064770v1

Quantile regression model for a diverse set of chemicals: Application to acute toxicity for green algae

Jonathan Villain , Gilles Durrieu , Ronan Bureau , Marie-Pierre Halm-Lemeille , Sylvain Lozano

Journal of Molecular Modeling, 2014, in press

Article dans une revue hal-01074269v1

Molecular basis of agonist docking in a human GPR103 homology model by site-directed mutagenesis and structure-activity relationship studies

Cindy Neveu , Fabienne Dulin , Benjamin Lefranc , Ludovic Galas , Colas Calbrix et al.

British Journal of Pharmacology, 2014, 171 (19), pp.4425-4439. ⟨10.1111/bph.12808⟩

Article dans une revue hal-01973604v1

The effect of different polychlorinated biphenyls on two aquatic models, the green alga Pseudokirchneriella subcapitata and the haemocytes from the European abalone Haliotis tuberculata

Marie-Pierre Halm-Lemeille , Abbaszadeh Fard Elham , Thomas Latire , Jean-Francois Ferard , Katherine Costil et al.

Chemosphere, 2014, 110, pp.120-128. ⟨10.1016/j.chemosphere.2014.02.023⟩

Article dans une revue istex hal-01076671v1

Protecting honey bees: identification of a new varroacide by in silico, in vitro, and in vivo studies

Fabienne Dulin , Céline Zatylny-Gaudin , Céline Ballandonne , Bertrand Guillet , Romain Bonafos et al.

Parasitology Research, 2014, pp.113, 4601-4610. ⟨10.1007/s00436-014-4150-z⟩

Article dans une revue hal-01116481v1

Assessment of cytotoxic and immunomodulatory properties of four antidepressants on primary cultures of abalone hemocytes (Haliotis tuberculata)

Laetitia Minguez , Marie-Pierre Halm-Lemeille , Katherine Costil , Ronan Bureau , Jean-Marc Lebel et al.

Aquatic Toxicology, 2014, 153, pp.3 - 11. ⟨10.1016/j.aquatox.2013.10.020⟩

Article dans une revue hal-01800718v1

Assessment of the genotoxic and carcinogenic potentials of 3-aminothiophene derivatives using in vitro and in silico methodologies

Alban Lepailleur , Ronan Bureau , Marie-Pierre Halm-Lemeille , Michel Bouquet , Regis Pecquet et al.

Journal of Applied Toxicology, 2013, 34 (7), pp.775-786. ⟨10.1002/jat.2938⟩

Article dans une revue istex hal-01077085v1

Corrigendum to “Interpretation of honeybees contact toxicity associated to acetylcholinesterase inhibitors” [Ecotoxicol. Environ. Saf. 79 (2012) 13–21]

Fabienne Dulin , Marie-Pierre Halm-Lemeille , Sylvain Lozano , Alban Lepailleur , Jana Sopkova-de Oliveira Santos et al.

Ecotoxicology and Environmental Safety, 2013, 90, pp.183-184

Article dans une revue hal-02045963v1

Automated detection of structural alerts (chemical fragments) in (eco)toxicology

Alban Lepailleur , Guillaume Poezevara , Ronan Bureau

Computational and Structural Biotechnology Journal, 2013, 5 (6), pp.e201302013. ⟨10.5936/csbj.201302013⟩

Article dans une revue hal-01023826v1

Structural characterizations of oligopyridyl foldamers, α-helix mimetics

Jana Sopkova-de Oliveira Santos , Anne-Sophie Voisin-Chiret , Grégory Burzicki , Laure Sebaoun , Muriel Sebban et al.

Journal of Chemical Information and Modeling, 2012, 52 (2), pp.429-439. ⟨10.1021/ci200424a⟩

Article dans une revue hal-00996400v1

Interpretation of honeybees contact toxicity associated to acetylcholinesterase inhibitors

Fabienne Dulin , Marie-Pierre Halm-Lemeille , Sylvain Lozano , Alban Lepailleur , Jana Sopkova-de Oliveira Santos et al.

Ecotoxicology and Environmental Safety, 2012, 79, pp.13-21

Article dans une revue hal-00764808v1

Prediction of acute toxicity in fish by using QSAR methods and chemical modes of action

Sylvain Lozano , Elodie Lescot , Marie-Pierre Halm , Alban Lepailleur , Ronan Bureau et al.

Journal of Enzyme Inhibition and Medicinal Chemistry, 2010, 25 (2), pp.195-203. ⟨10.3109/14756360903169857⟩

Article dans une revue hal-02045937v1

Consensus QSAR Related to Global or MOA Models: Application to Acute Toxicity for Fish

Sylvain Lozano , Marie-Pierre Halm-Lemeille , Alban Lepailleur , Sylvain Rault , Ronan Bureau

Molecular Informatics, 2010, 29 (11), pp.803-813. ⟨10.1002/minf.201000104⟩

Article dans une revue istex hal-02045936v1

Review of 5-HT4R ligands: state of art and clinical applications

Ronan Bureau , Michel Boulouard , François Dauphin , Frank Lezoualc'H , Sylvain Rault

Current Topics in Medicinal Chemistry, 2010, 10 (5), pp.527-53. ⟨10.2174/156802610791111551⟩

Article dans une revue hal-00863093v1

Introduction of jumping fragments in combination with QSARs for the assessment of classification in ecotoxicology

Sylvain Lozano , Guillaume Poezevara , Marie-Pierre Halm , Elodie Lescot-Fontaine , Alban Lepailleur et al.

Journal of Chemical Information and Modeling, 2010, 50 (8), pp.1330-1339. ⟨10.1021/ci100092x⟩

Article dans une revue hal-01011322v1

Virtual Screening Discovery of New Acetylcholinesterase Inhibitors Issued from CERMN Chemical Library

Jana Sopkova-de Oliveira Santos , Aurélien Lesnard , Jean-Hugues Agondanou , Nathalie Dupont , Anne-Marie Godard et al.

Journal of Chemical Information and Modeling, 2010, 50 (3), pp.422-428. ⟨10.1021/ci900491t⟩

Article dans une revue hal-00705935v1

Synthesis of a cytisine/epibatidine hybrid: a radical approach

Nicolas Houllier , Marie-Claire Lasne , Ronan Bureau , Pierre Lestage , Jacques Rouden

Tetrahedron, 2010, 66 (47), pp.9231-9241. ⟨10.1016/j.tet.2010.09.079⟩

Article dans une revue istex hal-02045914v1

Receptor- and Ligand-Based Study on Novel 2,2′-Bithienyl Derivatives as Non-Peptidic AANAT Inhibitors

Alban Lepailleur , Stéphane Lemaître , Xiao Feng , Jana Sopkova-de Oliveira Santos , Philippe Delagrange et al.

Journal of Chemical Information and Modeling, 2010, 50 (3), pp.446-460. ⟨10.1021/ci9004805⟩

Article dans une revue hal-02045919v1

Novel antagonists of serotonin-4 receptors: synthesis and biological evaluation of pyrrolothienopyrazines.

Stéphane Lemaître , Alban Lepailleur , Ronan Bureau , Sabrina Butt-Gueulle , Véronique Lelong-Boulouard et al.

Bioorganic and Medicinal Chemistry, 2009, 17 (6), pp.2607-22. ⟨10.1016/j.bmc.2008.11.045⟩

Article dans une revue istex hal-00863300v1

Pharmacophores of 5-HT4 Receptor Ligands: Experience of CERMN and Implications for Drug Design

Ronan Bureau , Thibault Varin , Alban Lepailleur , Cyril Daveu , Stephane Lemaitre et al.

Current Computer Aided-Drug Design, 2008, 4 (3), pp.199-208. ⟨10.2174/157340908785747384⟩

Article dans une revue hal-05481683v1

3D Pharmacophore, hierarchical methods, and 5-HT4 receptor binding data.

Thibault Varin , Nicolas Saettel , Jonathan Villain , Aurélien Lesnard , François Dauphin et al.

Journal of Enzyme Inhibition and Medicinal Chemistry, 2008, 23 (5), pp.593-603. ⟨10.1080/14756360802204748⟩

Article dans une revue hal-00863343v1

Toward Safer Thrombolytic Agents in Stroke: Molecular Requirements for NMDA Receptor-Mediated Neurotoxicity

Jose Lopez-Atalaya , Benoit Roussel , Denis Levrat , Jerome Parcq , Olivier Nicole et al.

Journal of Cerebral Blood Flow and Metabolism, 2008, 28 (6), pp.1212-1221. ⟨10.1038/jcbfm.2008.14⟩

Article dans une revue hal-01972984v1

Toward Safer Thrombolytic Agents in Stroke: Molecular Requirements for NMDA Receptor-Mediated Neurotoxicity

Jose Lopez-Atalaya , Benoit Roussel , Denis Levrat , Jérôme Parcq , Olivier Nicole et al.

Journal of Cerebral Blood Flow and Metabolism, 2008, 28 (6), pp.1212-1221. ⟨10.1038/jcbfm.2008.14⟩

Article dans une revue hal-05509935v1

Synthesis and Biological Evaluation of Thienopyrrolizines, a New Family of CDK/GSK-3 Inhibitors

Christophe Rochais , Elodie Lescot , Vincent Lisowski , Alban Lepailleur , Jana Sopkova-de Oliveira Santos et al.

Journal of Enzyme Inhibition and Medicinal Chemistry, 2008, 19 (6), pp.585-593. ⟨10.1080/14756360400004565⟩

Article dans une revue hal-05481708v1

Synthesis of new dipyrrolo- and furopyrrolopyrazinones related to tripentones and their biological evaluation as potential kinases (CDKs1-5, GSK-3) inhibitors.

Christophe Rochais , Nghia Vu Duc , Elodie Lescot , Jana Sopkova-de Oliveira Santos , Ronan Bureau et al.

European Journal of Medicinal Chemistry, 2008, epub ahead of print. ⟨10.1016/j.ejmech.2008.05.011⟩

Article dans une revue hal-00319802v1

Novel aminoethylbiphenyls as 5-HT7 receptor ligands.

Magalie Paillet-Loilier , Frédéric Fabis , Alban Lepailleur , Ronan Bureau , Sabrina Butt-Gueulle et al.

Bioorganic and Medicinal Chemistry Letters, 2007, 17 (11), pp.3018-22. ⟨10.1016/j.bmcl.2007.03.054⟩

Article dans une revue istex hal-00865224v1

Definition of New Pharmacophores for Nonpeptide Antagonists of Human Urotensin-II. Comparison with the 3D-structure of Human Urotensin-II and URP

Elodie Lescot , Jana Sopkova-de Oliveira Santos , Christophe Dubessy , Hassan Oulyadi , Aurélien Lesnard et al.

Journal of Chemical Information and Modeling, 2007, 47 (2), pp.602-612. ⟨10.1021/ci6003948⟩

Article dans une revue istex hal-02179719v1

Molecular Modeling Studies Focused on 5-HT 7 versus 5-HT 1A Selectivity. Discovery of Novel Phenylpyrrole Derivatives with High Affinity for 5-HT 7 Receptors

Alban Lepailleur , Ronan Bureau , Magalie Paillet-Loilier , Frédéric Fabis , Nicolas Saettel et al.

Journal of Chemical Information and Modeling, 2005, 45 (4), pp.1075-1081. ⟨10.1021/ci050045p⟩

Article dans une revue istex hal-05481695v1

Phenylpyrroles, a new chemolibrary virtual screening class of 5-HT7 receptor ligands

Magalie Paillet-Loilier , Frédéric Fabis , Alban Lepailleur , Ronan Bureau , Sabrina Butt-Gueulle et al.

Bioorganic and Medicinal Chemistry Letters, 2005, 15 (16), pp.3753-3757. ⟨10.1016/j.bmcl.2005.05.059⟩

Article dans une revue hal-05481690v1

Molecular Design Based on 3D Pharmacophores. Applications to 5-HT 7 Receptors

Alban Lepailleur , Ronan Bureau , Stéphane Lemaître , François Dauphin , Jean-Charles Lancelot et al.

Journal of Chemical Information and Computer Sciences, 2004, 44 (3), pp.1148-1152. ⟨10.1021/ci030036l⟩

Article dans une revue istex hal-05481721v1

Graph Neural Network Based on Molecular and Pharmacophoric Features for Drug Design Applications

Mariana Brito Azevedo , Luc Brun , Pierre Héroux , Jean-Luc Lamotte , Ronan Bureau et al.

Workshop on Graph-based Representations in Pattern Recognition, Jun 2025, Caen, France. pp.47-57, ⟨10.1007/978-3-031-94139-9_5⟩

Communication dans un congrès hal-05110964v1

Selecting Outstanding Patterns Based on Their Neighbourhood

Etienne Lehembre , Ronan Bureau , Bruno Crémilleux , Bertrand Cuissart , Jean-Luc Lamotte et al.

20th International Symposium on Intelligent Data Analysis, IDA 2022, Apr 2022, Rennes, France. pp.185-198, ⟨10.1007/978-3-031-01333-1_15⟩

Communication dans un congrès hal-03658500v1

Improving SAR analysis via pharmacophoric feature selection and feature transformation

Hajar Rehioui , Abdelkader Ouali , Christophe Couronne , Jean-Luc Lamotte , Alban Lepailleur et al.

10th SFCi, Sep 2021, Lille, France

Communication dans un congrès hal-03786797v1

PrePeP – A Tool for the Identification and Characterization of Pan Assay Interference Compounds

Maksim Koptelov , Albrecht Zimmermann , Pascal Bonnet , Ronan Bureau , Bruno Crémilleux

24th ACM SIGKDD International Conference on Knowledge Discovery & Data Mining, Aug 2018, Londres, United Kingdom. pp.462-471, ⟨10.1145/3219819.3219849⟩

Communication dans un congrès hal-01939468v1

Quantile de régression : application à l'analyse de l'écotoxicité de molécules chimiques

Jonathan Villain , Ronan Bureau , Gilles Durrieu

46èmes Journées de Statistique, Jun 2014, Rennes, France

Communication dans un congrès hal-01074920v1

Comparing chemical fingerprints for ecotoxicology

Leander Schietgat , Bertrand Cuissart , Alban Lepailleur , Kurt de Grave , Bruno Crémilleux et al.

6èmes journées de la Société Française de Chémoinformatique, Oct 2013, Nancy, France

Communication dans un congrès hal-01023845v1

Définition of a global model to determine the ecotoxicity of chemical on algea

Villain Jonathan , Sylvain Lozano , Marie-Pierre Halm , Alban Lepailleur , Gilles Durrieu et al.

6ème journées de la société française de chemoinformatique, Oct 2013, Nancy, France

Communication dans un congrès hal-01266109v1

New measures of interest associated to chemical patterns: definition, implementation and experimental assessment

Leander Schietgat , Guillaume Poezevara , Ryan Bissell-Siders , Ronan Bureau , Bruno Crémilleux et al.

5èmes Journées de la Société Française de Chémoinformatique, Oct 2011, Cabourg, France

Communication dans un congrès hal-01021453v1

Pharmacophores vs Circular Fingerprints with Learned Feature Transformation Before Clustering. Comparative Studies on Bcr-Abl Data

Hajar Rehioui , Abdelkader Ouali , Alban Lepailleur , Jean-Luc Lamotte , Albrecht Zimmermann et al.

8th Chemoinformatics Strasbourg Summer School, Jun 2022, Strasbourg, France.

Poster de conférence hal-03786907v1

Demonstration of the occurrence of a non-transmembrane -helix in the extracellular loop 2 of GPR103

Karima Alim , Laure Guilhaudis , Isabelle Ségalas-Milazzo , David Vaudry , Julien Chuquet et al.

Congrès du Groupe français des peptides et des protéines (GFPP, 19, 2015), May 2015, Port-Bail, France

Poster de conférence hal-02543930v1

Découverte automatique de motifs chimiques associés à un profil d'activité : application pour la recherche de structures d'alertes en mutagénicité

Jean-Philippe Metivier , Alban Lepailleur , Aleksey Buzmakov , Guillaume Poezevara , Bruno Crémilleux et al.

7èmes Journées de la Société Française de Chémoinformatique, Oct 2015, Nice, France. 2015

Poster de conférence hal-01627308v1

Emerging Patterns as Structural Alerts for Computational Toxicology

Bertrand Cuissart , Guillaume Poezevara , Bruno Crémilleux , Alban Lepailleur , Ronan Bureau

Contrast Data Mining, James Bailey, chapitre 19, 2013, 978-1-4398-5432-7. ⟨10.1201/b12986-25⟩

Chapitre d'ouvrage hal-01024000v1

Mcl-1 modulating compounds for cancer treatment

Laurent Poulain , Anne-Sophie Voisin-Chiret , Jana Sopkova de Oliveira Santos , Ronan Bureau , Grégory Burzicki et al.

United States, Patent n° : US 20170071921 A1. 2019

Brevet inserm-02545394v1

MCL-1 Modulating compounds for Cancer Treatment

Laurent Poulain , Anne-Sophie Voisin-Chiret , Jana Sopkova de Oliveira Santos , Ronan Bureau , Grégory Burzicki et al.

France, Patent n° : WO 2015/132727. 2015

Brevet inserm-02545373v1

Automatic Discovery of Molecular Graph Patterns Inhibiting Multiple Drug Transporters

Guillaume Poezevara , Alban Lepailleur , Sylvain Lozano , Alban Arrault , Bertrand Cuissart et al.

2014

Autre publication scientifique hal-01024727v1

Knowledge Discovery in Pharmaceutical Drug Transport using Emerging Graph Patterns

Guillaume Poezevara , Alban Lepailleur , Ronan Bureau , Lancelot Lemoine , Bertrand Cuissart et al.

2014

Autre publication scientifique hal-01024743v1

Supervised classification and QSAR in ecotoxicology: comparison of two methods

Sylvain Lozano , Guillaume Poezevara , Bertrand Cuissart , Marie-Pierre Halm-Lemeille , Elodie Lescot-Fontaine et al.

2009

Autre publication scientifique hal-01016467v1

Assessement of chemical risk phrases in ecotoxicoloy: comparison of two methods

Sylvain Lozano , Guillaume Poezevara , Bertrand Cuissart , Marie-Pierre Halm-Lemeille , Elodie Lescot-Fontaine et al.

2009

Autre publication scientifique hal-01011345v1

Chargement...