Sabine Riffault

114
Documents

Présentation

Neonatal sensitivity to respiratory viruses: how can we protect young animals against infections?

During the first months of life, acute lower respiratory tract infections are the major cause of morbidity and mortality among young mammals. The respiratory syncytial virus (RSV) is the main causative agent for broncho-pneumonia in calves (bovine RSV) and bronchiolitis in infants (human RSV). These viral infections have the particularity to cause severe acute lower respiratory disease in young animals whereas they are usually benign in adults, affecting only the upper respiratory tract. Thus, RSV infections are major health issues both for infants and calves. The neonatal period is characterized by immune responses quantitatively and qualitatively different from the adults one, issues that I have chosen to address through the following ongoing projects :

(a) To decipher the immunological and inflammatory mechanisms at stake in the lung upon respiratory infection of newborn.

(b) To elaborate new vaccine strategies against RSV using subunit vaccines: ring nanoparticles formed by the recombinant viral nucleoprotein and the pre-fusion form of the RSV fusion protein.

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Publications

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Screening antivirals with a mCherry-expressing recombinant bovine respiratory syncytial virus: a proof of concept using cyclopamine

Jenna Fix , Delphyne Descamps , Marie Galloux , Cécile Ferret , Edwige Bouguyon et al.
Veterinary Research, 2023, 54 (1), pp.36. ⟨10.1186/s13567-023-01165-x⟩
Article dans une revue hal-04175283 v1

La muqueuse pulmonaire en période périnatale : un monde à comprendre pour lutter contre la sensibilité du jeune à la bronchiolite

Claire Chottin , Quentin Marquant , Vinciane Saint-Criq , Mark R. Thomas , Sabine Riffault et al.
Revue des Maladies Respiratoires, 2022, 39 (2), pp.104-107. ⟨10.1016/j.rmr.2022.01.012⟩
Article dans une revue hal-03625844 v1
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Longitudinal study of the immune response and memory following natural bovine respiratory syncytial virus infections in cattle of different age

Sara Hägglund , Katarina Näslund , Anna Svensson , Cecilia Lefverman , Hakan Enül et al.
PLoS ONE, 2022, 17 (9), pp.e0274332. ⟨10.1371/journal.pone.0274332⟩
Article dans une revue hal-03800200 v1
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Hyper-Enriched Anti-RSV Immunoglobulins Nasally Administered: A Promising Approach for Respiratory Syncytial Virus Prophylaxis

Emilie Jacque , Claire Chottin , Daphnée Laubreton , Michel Nogre , Cécile Ferret et al.
Frontiers in Immunology, 2021, 12, pp.683902. ⟨10.3389/fimmu.2021.683902⟩
Article dans une revue hal-03287358 v1

Le poumon est sensible aux effets locaux et à distance des microbiotes

Elliot Mathieu , Quentin Marquant , Delphyne Descamps , Sabine Riffault , Vinciane Saint-Criq et al.
Nutrition Clinique et Métabolisme, 2021, 35 (4), pp. 242-252. ⟨10.1016/j.nupar.2021.04.002⟩
Article dans une revue hal-03477849 v1
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Control of IFN-I responses by the aminopeptidase IRAP in neonatal C57BL/6 alveolar macrophages during RSV infection

Carole Drajac , Daphné Laubreton , Quentin Marquant , Claire Chottin , Cécile Ferret et al.
Mucosal Immunology, 2021, 14 (4), pp.949-962. ⟨10.1038/s41385-021-00402-w⟩
Article dans une revue hal-03244474 v1

The microbiota plays a critical role in the reactivity of lung immune components to innate ligands

Quentin Marquant , Daphné Laubreton , Carole Drajac , Elliot Mathieu , Edwige Bouguyon et al.
FASEB Journal, 2021, 35 (4), 15 p. ⟨10.1096/fj.202002338R⟩
Article dans une revue hal-03169721 v1
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Single-Shot Vaccines against Bovine Respiratory Syncytial Virus (BRSV): Comparative Evaluation of Long-Term Protection after Immunization in the Presence of BRSV-Specific Maternal Antibodies

Jean François Valarcher , Sara Hägglund , Katarina Näslund , Luc Jouneau , Ester Malmström et al.
Vaccines, 2021, 9 (3), 27 p. ⟨10.3390/vaccines9030236⟩
Article dans une revue hal-03182920 v1
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Regulatory B lymphocytes colonize the respiratory tract of neonatal mice and modulate immune responses of alveolar macrophages to RSV infection in IL-10-dependant manner

Daphné Laubreton , Carole Drajac , Jean-François Eléouët , Marie Anne Rameix-Welti , Richard Lo-Man et al.
Viruses, 2020, 12 (8), pp.822. ⟨10.3390/v12080822⟩
Article dans une revue hal-02938422 v1
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Michel Brémont (1953–2020)

Stephane Biacchesi , Sabine Riffault , Thierry Pineau , Muriel Vayssier Taussat , Vincent Béringue
Veterinary Research, 2020, 51 (1), pp.146. ⟨10.1186/s13567-020-00878-7⟩
Article dans une revue hal-03093574 v1
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A Single Shot Pre-fusion-Stabilized Bovine RSV F Vaccine is Safe and Effective in Newborn Calves with Maternally Derived Antibodies

Sabine Riffault , Sara Hägglund , Efrain Guzman , Katarina Näslund , Luc Jouneau et al.
Vaccines, 2020, 8 (2), pp.231. ⟨10.3390/vaccines8020231⟩
Article dans une revue hal-04671064 v1
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The Role of Insulin Regulated Aminopeptidase in Endocytic Trafficking and Receptor Signaling in Immune Cells

Delphyne Descamps , Irini Evnouchidou , Vivien Caillens , Carole Drajac , Sabine Riffault et al.
Frontiers in Molecular Biosciences, 2020, 7, ⟨10.3389/fmolb.2020.583556⟩
Article dans une revue (article de synthèse) hal-02972353 v1
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De novo protein design enables the precise induction of RSV-neutralizing antibodies

Fabian Sesterhenn , Che Yang , Jaume Bonet , Johannes T. Cramer , Xiaolin Wen et al.
Science, 2020, 368 (6492), ⟨10.1126/science.aay5051⟩
Article dans une revue hal-02677103 v1
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A single shot pre-fusion-stabilized bovine rsv f vaccine is safe and effective in newborn calves with maternally derived antibodies

Sabine Riffault , Sara Hägglund , Efrain Guzman , Katarina Näslund , Luc Jouneau et al.
Vaccines, 2020, 8 (2), 21 p. ⟨10.3390/vaccines8020231⟩
Article dans une revue hal-02677111 v1
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Boosting subdominant neutralizing antibody responses with a computationally designed epitope-focused immunogen

Fabian Sesterhenn , Marie Galloux , Sabrina S Vollers , Lucia Csepregi , Che Yang et al.
PLoS Biology, 2019, 17 (2), pp.e3000164. ⟨10.1371/journal.pbio.3000164⟩
Article dans une revue inserm-02138858 v1
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Paradigms of lung microbiota functions in health and disease, particularly, in asthma

Elliot Mathieu , Unai Escribano-Vazquez , Delphyne Descamps , Claire Cherbuy , Philippe Langella et al.
Frontiers in Physiology, 2018, 9, pp.1-11. ⟨10.3389/fphys.2018.01168⟩
Article dans une revue (article de synthèse) hal-02627730 v1
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Proteome analysis of bronchoalveolar lavage from calves infected with bovine respiratory syncytial virus-Insights in pathogenesis and perspectives for new treatments

Sara Hagglund , Krister Blodorm , Katarina Naslund , Karin Vargmar , Sara Bergstrom Lind et al.
PLoS ONE, 2017, 12 (10), pp.1-19. ⟨10.1371/journal.pone.0186594⟩
Article dans une revue hal-02620701 v1
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Pulmonary susceptibility of neonates to respiratory syncytial virus infection: a problem of innate immunity?

Carole Drajac , Daphnée Laubreton , Sabine Riffault , Delphyne Descamps
Journal of Immunology Research, 2017, ⟨10.1155/2017/8734504⟩
Article dans une revue (article de synthèse) hal-02628884 v1
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RSV N-nanorings fused to palivizumab-targeted neutralizing epitope as a nanoparticle RSV vaccine

Pierre Louis Hervé , Charlotte Deloizy , Delphyne Descamps , Marie-Anne Rameix Welti , Jenna J. Fix et al.
Nanomedicine: Nanotechnology, Biology and Medicine, 2017, 13 (2), pp.411-420. ⟨10.1016/j.nano.2016.08.006⟩
Article dans une revue hal-02628338 v1
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Bacteria isolated from lung modulate asthma susceptibility in mice

Aude Remot , Delphyne Descamps , Marie-Louise Noordine , Abdelhak Boukadiri , Elliot Mathieu et al.
The International Society of Microbiologial Ecology Journal, 2017, pp.1061-1074. ⟨10.1038/ismej.2016.181⟩
Article dans une revue hal-01595509 v1

Flt3 ligand improves the innate response to respiratory syncytial virus and limits lung disease upon RSV reexposure in neonate mice

Aude Remot , Delphyne Descamps , Luc Jouneau , Daphnée Laubreton , Catherine Dubuquoy et al.
European Journal of Immunology, 2016, 46 (4), pp.874-884. ⟨10.1002/eji.201545929⟩
Article dans une revue hal-01533877 v1

Non-invasive epicutaneous vaccine against Respiratory Syncytial Virus: Preclinical proof of concept

Pierre-Louis Hervé , Delphyne Descamps , Charlotte Deloizy , Véronique Dhelft , Daphné Laubreton et al.
Journal of Controlled Release, 2016, 243, pp.146-159. ⟨10.1016/j.jconrel.2016.10.003⟩
Article dans une revue hal-01425790 v1
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A bovine respiratory syncytial virus model with high clinical expression in calves with specific passive immunity

Krister Blodorn , Sara Hagglund , Dolores Gavier-Widén , Jean Francois J. F. Eleouet , Sabine Riffault et al.
BMC Veterinary Research, 2015, 11, ⟨10.1186/s12917-015-0389-6⟩
Article dans une revue hal-02640254 v1
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Visualizing the replication of respiratory syncytial virus in cells and in living mice

Marie-Anne Rameix-Welti , Ronan Le Goffic , Pierre-Louis Hervé , Julien Sourimant , Aude Remot et al.
Nature Communications, 2014, 5, ⟨10.1038/ncomms6104⟩
Article dans une revue hal-02633568 v1
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Vaccine Safety and Efficacy Evaluation of a Recombinant Bovine Respiratory Syncytial Virus (BRSV) with Deletion of the SH Gene and Subunit Vaccines Based On Recombinant Human RSV Proteins: N-nanorings, P and M2-1, in Calves with Maternal Antibodies

Krister Blodorn , Sara Hagglund , Jenna J. Fix , Catherine C. Dubuquoy , Boby Makabi-Panzu et al.
PLoS ONE, 2014, 9 (6), ⟨10.1371/journal.pone.0100392⟩
Article dans une revue hal-02639198 v1

Characterization of an experimental vaccine for bovine respiratory syncytial virus

Sara Hagglund , Kefei Hu , Krister Blodorn , Boby Makabi-Panzu , Anne-Laure Gaillard et al.
Clinical and Vaccine Immunology, 2014, 21 (7), pp.997-1004. ⟨10.1128/CVI.00162-14⟩
Article dans une revue hal-01204394 v1

A Novel Subnucleocapsid Nanoplatform for Mucosal Vaccination against Influenza Virus That Targets the Ectodomain of Matrix Protein 2

Pierre-Louis Hervé , Mariam Raliou , Christiane Bourdieu , Catherine C. Dubuquoy , Agnes Petit-Camurdan et al.
Journal of Virology, 2014, 88 (1), pp.325-338. ⟨10.1128/JVI.01141-13⟩
Article dans une revue hal-02637841 v1

Mucosal Imprinting of Vaccine-Induced CD8(+) T Cells Is Crucial to Inhibit the Growth of Mucosal Tumors

Federico Sandoval , Magali Terme , Mevyn Nizard , Cecile Badoual , Michel-Francis Bureau et al.
Science Translational Medicine, 2013, 5 (172), ⟨10.1126/scitranslmed.3004888⟩
Article dans une revue hal-02650685 v1
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Nucleoprotein nanostructures combined with adjuvants adapted to the neonatal immune context: a candidate mucosal RSV vaccine

Aude A. Remot , Xavier X. Roux , Catherine C. Dubuquoy , Jenna J. Fix , Stephan S. Bouet et al.
PLoS ONE, 2012, 7 (5), Non paginé. ⟨10.1371/journal.pone.0037722⟩
Article dans une revue hal-01001405 v1

Neonatal lung immune responses show a shift of cytokines and transcription factors toward Th2 and a deficit in conventional and plasmacytoid dendritic cells

Xavier X. Roux , Aude A. Remot , Agnes A. Petit Camurdan , Marie-Anne Nahori , Helene Kiefer-Biasizzo et al.
European Journal of Immunology, 2011, 41 (10), pp.2852-2861. ⟨10.1002/eji.201041224⟩
Article dans une revue hal-02644846 v1

A new subunit vaccine based on nucleoprotein nanoparticles confers partial clinical and virological protection in calves against bovine respiratory syncytial virus

Sabine Riffault , Gilles G. Meyer , Martine Deplanche , Catherine C. Dubuquoy , Guillaume Durand et al.
Vaccine, 2010, 28 (21), pp.3722-3734. ⟨10.1016/j.vaccine.2010.03.008⟩
Article dans une revue hal-02658778 v1

Infectious bursal disease subviral particles displaying the foot-and-mouth disease virus major antigenic site

Michelle Rémond , Bruno B. da Costa , Sabine Riffault , Satya Parida , Emmanuel Breard et al.
Vaccine, 2009, 27 (1), pp.93-98. ⟨10.1016/j.vaccine.2008.10.036⟩
Article dans une revue istex hal-02664065 v1

Protective Role for Protease-Activated Receptor-2 against Influenza Virus Pathogenesis via an IFN-gamma-Dependent Pathway

Khaled Khoufache , Fanny Lebouder , Eric E. Morello , Fabrice Laurent , Sabine Riffault et al.
Journal of Immunology, 2009, 182 (12), pp.7795-7802. ⟨10.4049/jimmunol.0803743⟩
Article dans une revue hal-02663202 v1

Plasmacytoid dendritic cells migrate in afferent skin lymph

Florentina Pascale , Vanessa Contreras , Michel Bonneau , Alexandre Courbet , Stefan Chilmonczyk et al.
Journal of Immunology, 2008, 180 (9), pp.5963-5972. ⟨10.4049/jimmunol.180.9.5963⟩
Article dans une revue hal-01193693 v1
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Sub-nucleocapsid nanoparticles: a nasal vaccine against respiratory syncytial virus

Xavier X. Roux , Catherine C. Dubuquoy , Guillaume Durand , Thi-Lan Tran-Tolla , Nathalie Castagné et al.
PLoS ONE, 2008, 3 (3), pp.e1766. ⟨10.1371/journal.pone.0001766⟩
Article dans une revue hal-02655935 v1

Recombinant rotavirus inner core proteins produced in the milk of transgenic rabbits confer a high level of protection after intrarectal delivery.

Eric Soler , Nathalie Parez , Bruno Passet , Catherine Dubuquoy , Sabine Riffault et al.
Vaccine, 2007, 25 ((34)), pp.6373-80. ⟨10.1016/j.vaccine.2007.06.011⟩
Article dans une revue istex hal-00815843 v1

Efficacy of particle-based DNA delivery for vaccination of sheep against FMDV

V. Niborski , Y. Li , Fiona Brennan , M. Lane , A.M. Torché et al.
Vaccine, 2006, 24 (49-50), pp.7204-7213. ⟨10.1016/j.vaccine.2006.06.048⟩
Article dans une revue istex hal-02658133 v1

Replication of Bovine respiratory syncytial virus in murine cells depends on type I interferon-receptor functionality

Sabine Riffault , Catherine C. Dubuquoy , Nathalie Castagné , Eric Baranowski , Bernard Charley et al.
Journal of General Virology, 2006, 87 (8), pp.2145-2148. ⟨10.1099/vir.0.82091-0⟩
Article dans une revue hal-02661692 v1

Porcine innate and adaptative immune responses to influenza and coronavirus infections

Bernard Charley , Sabine Riffault , Kristien van Reeth
Annals of the New York Academy of Sciences, 2006, 1081 (1), pp.130-136. ⟨10.1196/annals.1373.014⟩
Article dans une revue hal-02662172 v1
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Antigen presenting cells in mucosal sites of veterinary species

Karin Haverson , Sabine Riffault
Veterinary Research, 2006, 37 (3), pp.339-358. ⟨10.1051/vetres:2006005⟩
Article dans une revue hal-00903028 v1

Migratory monocytes and granulocytes are major lymphatic carriers of Salmonella from tissue to draining lymph node

Michel M. Bonneau , Mathieu Epardaud , Fabrice Payot , Violeta Niborski , Marie-Isabelle Thoulouze et al.
Journal of Leukocyte Biology, 2006, 79, pp.268-276. ⟨10.1189/jlb.0605288⟩
Article dans une revue hal-02666924 v1

TLR9 pathway is involved in adjuvant effects of plasmid DNA-based vaccines

Daniela Tudor , Catherine C. Dubuquoy , Valérie Gaboriau , Francois F. Lefèvre , Bernard Charley et al.
Vaccine, 2005, 23 (10), pp.1258-1264. ⟨10.1016/j.vaccine.2004.09.001⟩
Article dans une revue istex hal-02680528 v1

Type I IFN modulates the immune response induced by DNA vaccination to pseudorabies virus glycoprotein C

D. Tudor , Sabine Riffault , C. Carrat , Francois F. Lefèvre , Marielle Bernoin et al.
Virology, 2001, 286, pp.197-205
Article dans une revue hal-02671713 v1
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Interferon-alpha-producing cells are localized in gut-associated lymphoid tissues in transmissible gastroenteritis virus (TGEV) infected piglets

Sabine Riffault , C. Carrat , K. van Reeth , M. Pensaert , Bernard Charley
Veterinary Research, 2001, 32 (1), pp.71-79
Article dans une revue hal-02681357 v1
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Interferon-alpha-producing cells are localized in gut-associated lymphoid tissues in transmissible gastroenteritis virus (TGEV) infected piglets

Sabine Riffault , Charles Carrat , Kristien van Reeth , Maurice Pensaert , Bernard Charley
Veterinary Research, 2001, 32 (1), pp.71-79. ⟨10.1051/vetres:2001111⟩
Article dans une revue hal-00902690 v1

Transient IFN-gamma synthesis in the lymph node draining a dermal site loaded with UV-irradiated herpes simplex virus type 1 : an NK- and CD3-dependent process regulated by IL-12 but not by IFN-alpha/beta

Sabine Riffault , C. Carrat , G. Milon , Bernard Charley , J.H. Colle
Journal of General Virology, 2000, 81, pp.2365-2373
Article dans une revue hal-02692065 v1

Vesicular stomatitis virus and pseudorabies virus induce a vig 1/cig5 homologue in mouse dendritic cells via different pathways

Pierre Boudinot , Sabine Riffault , S. Salhi , C. Carrat , C. Sedlik et al.
Journal of General Virology, 2000, 81, pp.2675-2682
Article dans une revue hal-02695563 v1

vig-1, a new fish gene induced by the rhabdovirus glycoprotein, has a virus-induced homologue in humans and shares conserved motifs with the MoaA family

Pierre Boudinot , Pascale Massin , Mar Blanco , Sabine Riffault , Abdenour Benmansour
Journal of Virology, 1999, 73 (3), pp.1846-1852
Article dans une revue hal-02697891 v1

In vivo induction of interferon-alpha in pig by non-infectious coronavirus: tissue localization and in situ phenotypic characterization of interferon-alpha-producing cells

Sabine Riffault , C. Carrat , Lydia Besnardeau , Claude La Bonnardière , Bernard Charley
Journal of General Virology, 1997, 78, pp.2483-2487
Article dans une revue hal-02687594 v1
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Reconstituted coronavirus TGEV virosomes lose the virus ability to induce porcine interferon-alpha production

Sabine Riffault , J Grosclaude , Muriel Vayssier Taussat , H Laude , B Charley
Veterinary Research, 1997, 28 (1), pp.77-86
Article dans une revue hal-00902460 v1
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Reconstituted coronavirus TGEV virosomes lose the virus ability to induce porcine interferon-alpha production

Sabine Riffault , Jeanne Grosclaude , Muriel Vayssier Taussat , Hubert Laude , Bernard Charley
Veterinary Research, 1997, 28 (2), pp.105-114
Article dans une revue hal-02685172 v1

Herpes simplex virus induces appearance of interferon-alpha/bêta-producing cells and partially interferon-alpha/bêta-dependent accumulation of leukocytes in murine regional lymph nodes

Sabine Riffault , M.L. Eloranta , C. Carrat , K. Sandberg , Bernard Charley et al.
Journal of Interferon and Cytokine Research, 1996, 16, pp.1007-1014
Article dans une revue hal-02690475 v1

Evaluation de la compétence immunitaire innée chez des veaux en période périnatale, en relation avec l’occurence de diarrhées

Sabine Riffault , Luc Jouneau , Denis Laloë , Aurélie Vinet , Rachel Lefebvre et al.
Symposium du Club d'Immunologie et Vaccinologie Vétérinaires (CIVVet), May 2023, Toulouse, France
Communication dans un congrès hal-04186459 v1

Comparaison des signatures cytokiniques innées des compartiments pulmonaire et sanguin chez le veau

Cécile Ferret , Florence Carreras , Claire Chottin , Luc Jouneau , Sonia Lacroix-Lamandé et al.
Symposium du Club d’Immunologie et Vaccinologie Vétérinaires (CIVVet), May 2023, Toulouse, France
Communication dans un congrès hal-04186480 v1
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Identification de régions du génome et de gènes candidats associés au niveau de réponse immune innée de veaux Holstein

Pauline Martin , Luc Jouneau , Sébastien Taussat , Aurélie Vinet , Rachel Lefebvre et al.
​26. Rencontres autour des Recherches sur les Ruminants, Institut de l'élevage [IDELE]; INRAE, Dec 2022, Paris, France. pp.187-190
Communication dans un congrès hal-04033238 v1
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Identification of genome regions and promising candidate genes linked to innate immune capacity on young Holstein calves

P Martin , S Fresco , L Jouneau , S Taussat , A Vinet et al.
12th World Congress on Genetics Applied to Livestock Production, Jul 2022, Rotterdam, Netherlands. ⟨10.15454/1.5483257052131956E12⟩
Communication dans un congrès hal-03731335 v1

Efficacy of subunit BRSV vaccines in calves : towards a translational model for infant vaccination?

Sabine Riffault
7th European Veterinary Immunology Workshop (EVIW), European Veterinary Immunology Group (EVIG), Aug 2021, Virtual format, Serbia
Communication dans un congrès hal-04466713 v1

Microbiota educates innate immune response to Toll-like receptors ligands and RSV infection in lung

Quentin Marquant , Daphné Lebreton , Carole Drajac , Elliot Mathieu , Marie-Louise Noordine et al.
international congress ERS, European Respiratory Society, Oct 2019, Madrid, Spain
Communication dans un congrès hal-04295177 v1

Bacteria isolated from lung as biotherapeutics in asthma.

Aude Remot , Jennifer Palomo , Alexandre David-Hachette , Elliot Mathieu , Delphyne Descamps et al.
international congress ERS, European Respiratory Society, Sep 2019, Madrid, Spain
Communication dans un congrès hal-04295043 v1

Driving immune responses with synthetic proteins - development of de novo designed immunogens to elicit respiratory syncytial virus neutralizing antibodies

Fabian Sesterhenn , Che Yang , Jaume Bonet , Marie Galloux , Xiaolin Wen et al.
32nd Annual Symposium of the Protein-Society, Protein Society. USA. Beckman Coulter Inc, USA. Pall ForteBio, USA. Bristol-Myers Squibb (BMS), USA., Jul 2018, Boston, United States. pp.2
Communication dans un congrès hal-02734561 v1

Preclinicalevaluation of anovel non-Invasive epicutaneous vaccine against respiratory syncytial virus

Pierre-Louis Hervé , Delphyne Descamps , Charlotte Deloizy , Veronique Dhelft , Daphne Laubreton et al.
Annual Meeting of the American-Academy-of-Allergy-Asthma-and-Immunology, Mar 2017, Atlanta, Georgia. pp.1
Communication dans un congrès hal-01605167 v1

Respiratory syncytial virus targets a fetally developed B cell population with regulatory functions which predicts disease severity

D. Zhivaki , S. Lemoine , M. -A Rameix-Welti , A. Lim , Delphyne Descamps et al.
International Congress of Immunology (ICI), Aug 2016, Melbourne, Australia. pp.1
Communication dans un congrès hal-02742028 v1
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Impact of the development of the lung microbiota on neonatal immunity

Aude Remot , Marie-Louise M.-L. Noordine , Chantal C. Bridonneau , Delphyne Descamps , Sabine Riffault et al.
20. Colloque du Club des Bactéries Lactiques, Jun 2015, Lille, France
Communication dans un congrès hal-02742693 v1
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Lung neonatal responses to respiratory syncytial virus reveal deficiencies in dendritic cells and type I interferon in a mouse model of airway enhanced disease

Aude Remot , Luc Jouneau , Delphyne Descamps , Catherine C. Dubuquoy , Stephan S. Bouet et al.
8. Word Immune Regulation Meeting, Mar 2014, Davos, Switzerland
Communication dans un congrès hal-02740120 v1

A novel proteic nano-platform for antigens: application to mucosal influenza vaccination.

Sabine Riffault
2eme séminaire du département de microbiologie de IRBA, 2012, Paris, France
Communication dans un congrès hal-02744447 v1

Transcriptomic analysis of neonatal vs. adult lung early responses to RSV reveals key roles for DC and type I IFN in controlling immunopathologic imprinting.

Aude Remot , Luc Jouneau , Catherine Dubuquoy , Stephan Bouet , Jérôme Lecardonnel et al.
Diversity and plasticity of DCs, Dec 2012, Paris, France
Communication dans un congrès hal-01191380 v1

Adapting vaccine formulation to the neonatal context is required to obtain safe protection against the respiratory syncytial virus

Aude Remot , Xavier Roux , Catherine Dubuquoy , Julie Bernard , Mohammed Moudjou et al.
European Congress of Immunology, Sep 2012, Glasgow, Scotland, United Kingdom. pp.727
Communication dans un congrès hal-01003266 v1

A novel proteic nano-platform for antigens: application to musocal influenza vaccination.

Mariam Raliou , Pierre-Louis Hervé , Christophe Chevalier , Christiane Bourdieu , Catherine Dubuquoy et al.
VIRUS-LIKE PARTICLE & NANO-PARTICLE VACCINES, Nov 2012, Cannes, France
Communication dans un congrès hal-01191379 v1

Newborns are particularly prone to respiratory syncytial virus infection: why ? How to protect them ?

Aude Remot , Agnes A. Petit Camurdan , Catherine C. Dubuquoy , Julie Bernard , Mohammed M. Moudjou et al.
Journées d'Animation Scientifique du Département Santé Animale, May 2011, Fréjus, France. 130 p
Communication dans un congrès hal-02744806 v1

Which immune lung features relate to the higher severity of respiratory syncytial virus infection in newborns?

Aude Remot , Sabine Riffault
Séminaire, Institute for Virology, University of veterinary medicine, Sep 2010, Hannovre, Germany
Communication dans un congrès hal-02813237 v1

Vaccination of newborn mice with the nucleoprotein of human RSV confers viral protection but enhances pulmonary inflammation after challenge

Agnes A. Petit Camurdan , Catherine C. Dubuquoy , Julie Bernard , Jean Francois J. F. Eleouet , Sabine Riffault
Journées d'Animation Scientifique du Département Santé Animale, May 2009, Port d'Albret, France
Communication dans un congrès hal-02752386 v1

A New Subunit Vaccine Based on Nucleocapsid Protein Nanoparticles Confers Partial Protection in Calves Against Respiratory Syncytial Virus

Sabine Riffault , Gilles G. Meyer , Guillaume Durand , Marion Soulestin , Catherine C. Dubuquoy et al.
3. European Veterinary Immunology Workshop EVIW, Sep 2009, Berlin, Germany. n.p
Communication dans un congrès hal-02824159 v1

Protective role for Protease-Activated-Receptor-2 against Influenza virus Pathogenesis via an Interferon-Y dependent pathway

Khaled Khoufache , Fanny Le Bouder , Eric E. Morello , Fabrice Laurent , Sabine Riffault et al.
Journées d'animation scientifique du Département Santé Animale, May 2009, Port d'Albret, France
Communication dans un congrès hal-02755857 v1

Plasmacytoid dendritic cells migrate in afferent skin and oro-nasal lymph

Florentina Pascale , Alexandre Courbet , Michel M. Bonneau , Violeta Niborski , Mathieu Epardaud et al.
Réunion de la Société Française d'Immunologie et Club Francophone des Cellules Dendritiques, Jun 2008, Paris, France. n.p
Communication dans un congrès hal-02818326 v1

Une nouvelle stratégie vaccinale contre le virus respiratoire syncytial, basée sur des assemblages nanoparticulaires de la protéine de nucléocapside

Sabine Riffault , Agnes A. Petit Camurdan , Xavier X. Roux , Catherine C. Dubuquoy , Guillaume Durand et al.
10. Journées Francophones de Virologie, Mar 2008, Paris, France. n.p
Communication dans un congrès hal-02815443 v1

Evaluation of a new respiratory syncytial virus vaccine candidate

Gilles G. Meyer , Martine Deplanche , Catherine C. Dubuquoy , Marion Soulestin , Guillaume Durand et al.
25. World Buiatrics Congress, Jul 2008, Budapest, Hungary. n.p
Communication dans un congrès hal-02822661 v1

A New Subunit Vaccine Based on Nucleocapsid Protein Nanoparticles Confers Protection Against Respiratory Syncytial Virus

Sabine Riffault , Guillaume Durand , Marion Soulestin , Catherine C. Dubuquoy , Martine Deplanche et al.
Réunion du Club de Vaccinologie de la Société Française d'Immunologie, Nov 2008, Paris, France. n.p
Communication dans un congrès hal-02815657 v1

Evaluation dans l'espèce cible d'une nouvelle stratégie vaccinale contre le virus respiratoire syncytial bovin, basée sur des assemblages nanoparticulaires de la protéine de nucléocapside

Sabine Riffault , Guillaume Durand , Marion Soulestin , Catherine C. Dubuquoy , Nathalie Castagné et al.
Journée d'Animation du Réseau Immunologie des Animaux Domestiques (IAD), Nov 2007, Montpellier, France. n.p
Communication dans un congrès hal-02823927 v1

La vaccination nasale avec la nucléoprotéine du virus respiratoire syncytial confère une immunité protectrice contre une épreuve virale

Xavier X. Roux , Agnes A. Petit Camurdan , Catherine C. Dubuquoy , Guillaume Durand , Nathalie Castagné et al.
Journées d'Animation Scientifique du Département de Santé Animale, Jun 2007, Tours, France
Communication dans un congrès hal-02752791 v1

Type I interferon producing cells (ipc) can gain lymph nodes via the afferent lymphatic route

Florentina Pascale , Vanessa Contreras , Alexandre Courbet , Michel Bonneau , Stefan Chilmonczyk et al.
13. International Congress of Immunology, Aug 2007, Rio de Janeiro, Brazil. 1 p
Communication dans un congrès hal-01193698 v1

Plasmacytoid DC migrate in afferent lymph Club Francophone des cellules dendritiques

Florentina Pascale , Alexandre Courbet , Michel M. Bonneau , Celine C. Urien , Catherine C. Dubuquoy et al.
Congrès annuel de la Société Française d'Immunologie (SFI), Nov 2007, Lyon, France. n.p
Communication dans un congrès hal-02819602 v1

Mucosal vaccination with the nucleoprotein of respiratory syncytial virus confers protective immunity

Xavier Roux , Catherine C. Dubuquoy , Nathalie Castagné , Julie Bernard , Jean Francois J. F. Eleouet et al.
Congrès Européen d'Immunologie des Muqueuses (EMIG), Oct 2006, Paris, France. n.p
Communication dans un congrès hal-02814536 v1

Natural Interferon (IFN) producing cells can reach lymph node via afferent lymph

Florentina Pascale , Alexandre Courbet , Michel M. Bonneau , Celine C. Urien , Catherine C. Dubuquoy et al.
2. European Veterinary Immunology Workshop, Sep 2006, Paris, France. n.p
Communication dans un congrès hal-02818733 v1

Porcine innate and adaptative immune responses to influenza and coronavirus infections

Bernard Charley , Sabine Riffault , Kristien van Reeth
8. Conference of the Society for Tropical Veterinary Medicine, Jun 2005, Hanoi, Vietnam. n.p
Communication dans un congrès hal-02831435 v1

Etude des cellules dendritiques et macrophages du poumon : comparaison adultes nouveaux-nés

Xavier X. Roux , Catherine C. Dubuquoy , Bernard Charley , Sabine Riffault
Journées d'Animation Scientifique du Département de Santé Animale, May 2005, Batz-sur-Mer, France
Communication dans un congrès hal-02759410 v1

Particle-based DNA vaccination against Foot-and-Mouth disease is efficient in sheep

Violeta Niborski , Y. Li , C. Stirling , Fiona Brennan , A.M. Torché et al.
Rencontres du Réseau français d'Immunologie des Animaux Domestiques (IAD), Oct 2005, Lyon, France. n.p
Communication dans un congrès hal-02832501 v1

Etude des bases moléculaires de la spécificité d’espèce du VRS et essais de développement d’un modèle murin pour le VRS bovin

Jean Francois J. F. Eleouet , Nathalie Castagné , Eric E. Baranowski , Martine Deplanche , Gilles G. Meyer et al.
Séminaire bilan du programme de recherche Zoonoses, Sep 2004, Nouzilly, France. n.p
Communication dans un congrès hal-02832498 v1

Cellules sécrétrices d'IFN alpha dans le tissu lymphoïde associé à la muqueuse intestinale du porcelet infecté par le virus GET

Sabine Riffault , C. Carrat , M. Enache , K. van Reeth , M. Pensaert et al.
Immunité muqueuse, Jun 1999, Toulouse, France
Communication dans un congrès hal-02770429 v1

Signatures immuno-metabolomiques des cellules immunitaires innées bovines

Aude Remot , Guillaume Sallé , Cécile Ferret , Ambre Baillou , Mégane Fernandez et al.
Symposium Club d’Immunologie et Vaccinologie Vétérinaire (CIVVet), May 2023, Toulouse, France
Poster de conférence hal-04186688 v1
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Immunostimulation of bovine neonate immune cells : metabolomic and transcriptomic responses

Aude Remot , Guillaume Sallé , Cécile Ferret , Mégane Fernandez , Florence Carreras et al.
Journées d'animation scientifique du département Santé Animale (JAS SA), Oct 2022, Anglet, France
Poster de conférence hal-04172281 v1

Microbiota impacts the susceptibility of the airway inflammatory responses

Delphyne Descamps , Sabine Riffault
Journée de la recherche respiratoire, Oct 2021, Brest, France
Poster de conférence hal-04208426 v1
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Immunomodulation de la sensibilité néonatale au Virus Respiratoire Syncytial: Vers une approche thérapeutique basée sur des bactéries primo-colonisatrices du poumon

Quentin Marquant , Daphné Laubreton , Carole Drajac , Elliot Mathieu , Edwige Bouguyon et al.
Vaincre la mucoviscidose, Feb 2020, Paris, France
Poster de conférence halshs-04172975 v1
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BACTERIA ISOLATED FROM LUNG AS BIOTHERAPEUTICS IN ASTHMA

Elliot Mathieu , Jennifer Palomo , Alexandre David-Hachette , Quentin Marquant , Aude Remot et al.
international congress ERS, Sep 2019, Madrid, Spain
Poster de conférence hal-04295216 v1

Microbiota impacts the susceptibility of the airway inflammatory responses

Delphyne Descamps , Sabine Riffault , Muriel Thomas , Quentin Marquant
European Respiratory Society, Sep 2019, Madrid, Spain
Poster de conférence hal-04208429 v1

Control of nonatal type I interferon responses by IRAP upon RSV infection

Carole Drajac , Daphnée Laubreton , Loredana Saveanu , Sabine Riffault , Delphyne Descamps
IRAP 2017, 3rd international symposium, 2017, Paris, France. 2017
Poster de conférence hal-01605602 v1
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Lung neonatal responses to respiratory syncytial virus reveal deficiencies in dendritic cells and type I interferon in a mouse model of airway enhanced disease

Aude Remot , Delphyne Descamps , Luc Jouneau , Catherine C. Dubuquoy , Stephan S. Bouet et al.
13. International Symposium on Dendritic Cells, Sep 2014, Tours, France. 2014
Poster de conférence hal-02739158 v1
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Impact of the development of the pulmonary microbiota on neonatal immunity

Aude Remot , Alix Penel , Mathilde Bauducel , Chantal C. Bridonneau , Delphyne Descamps et al.
8. Word Immune Regulation Meeting, Mar 2014, Davos, Switzerland. 2014
Poster de conférence hal-02742629 v1
Image document

Recombinant hRSV expressing mCherry or luciferase without fitness alteration

Marie-Anne Rameix-Welti , Julien Sourimant , Jenna J. Fix , Aude Remot , Sabine Riffault et al.
14. International Negative Strand Virus Meeting, Jun 2013, Granada, Spain. , 2013
Poster de conférence hal-02744494 v1

Impact of the development of the pulmonary microbiota on neonatal immunity

Aude Remot , Alix Penel , Mathilde Bauducel , Chantal C. Bridonneau , Delphyne Descamps et al.
AgreenSkills Annual Meeting 2013, Nov 2013, Louvain, Belgium. 87 p., 2013
Poster de conférence hal-02748060 v1

Transcriptomic analysis of neonatal vs. adult lung early responses to RSV reveals key roles for DC and type I IFN in controlling immunopathologic imprinting

Aude Remot , Luc Jouneau , Catherine Dubuquoy , Stephan S. Bouet , Jerome Lecardonnel et al.
Diversity and plasticity of DCs, Club Francophone des Cellules Dendritiques, Dec 2012, Paris, France
Poster de conférence hal-02935313 v1

Age-related differences in the lung tissue susceptibility to Respiratory Syncytial Virus

Aude A. Remot , Azadeh Djavidi , Catherine C. Dubuquoy , Isabelle Schwartz-Cornil , Fabrice Laurent et al.
4. European Veterinary Immunology Workshop (EVIW), Sep 2012, Edimbourg, United Kingdom. 2012
Poster de conférence hal-02748020 v1
Image document

Neonatal Nasal Vaccination with the Nucleoprotein of the Respiratory Syncytial Virus Elicits Virus-protective but Airway-pathogenic Th2-biased Immunity that can be Modulated by the Choice of Adjuvants

Aude Remot , Xavier X. Roux , Catherine C. Dubuquoy , Julie Bernard , Mohammed M. Moudjou et al.
15. International Congress of Mucosal Immunology (ICMI 2011) "Peace and War at Mucosal Surfaces", Jul 2011, Paris, France. , 2011
Poster de conférence hal-02745248 v1

Nucleoprotein nanostructures: a mucosal subunit vaccine candidate for neonates protective against the respiratory syncytial virus

Aude Remot , Xavier X. Roux , Catherine C. Dubuquoy , Julie Bernard Theron , Jenna J. Fix et al.
Journées de l’Ecole doctorale ABIES, Mar 2011, Paris, France. 2011
Poster de conférence hal-02805147 v1
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Nucleoprotein nanostructures: a mucosal subunit vaccine candidate for neonates protective against the respiratory syncytial virus

Aude Remot , Xavier X. Roux , Catherine C. Dubuquoy , Julie Bernard Theron , Jenna J. Fix et al.
Cold spring Harbor meeting: Harnessing immunity to treat and prevent diseases, Nov 2011, New York, United States. 79 p., 2011
Poster de conférence hal-02745116 v1
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Rôle des récepteurs PAR et TLR pulmonaires dans les réponses néonatales aux infections virales respiratoires

Aude Remot , Azadeh Djavidi , Agnes Petit-Camurdan , Catherine C. Dubuquoy , Isabelle Schwartz-Cornil et al.
6. Colloque DOC’J 2010 "La biologie et les sciences qui gravitent autour d'elle", May 2010, Jouy-en-Josas, France. , 2010
Poster de conférence hal-02754675 v1

Vaccination of newborn mice with the nucleoprotein of human RSV confers viral protection but enhances pulmonary inflammation after challenge

A Petit-Camurdan , Catherine C. Dubuquoy , Julie Bernard , Jf Eléouët , Sabine Riffault
Journées d’Animation Scientifique du Département Santé Animale, 2009, Port d'Albret, France. pp.Inconnu, 2009
Poster de conférence hal-02815224 v1

Protective role for Protease-Activated-Receptor-2 against Influenza virus Pathogenesis via an Interferon-Y dependent pathway

Khaled Khoufache , F Lebouder , Eric Morello , Fabrice Laurent , Sabine Riffault et al.
Journées d’Animation Scientifique du Département Santé Animale, 2009, Port d'Albret, France. pp.Inconnu, 2009
Poster de conférence hal-02815269 v1

Infectious bursal disease subviral particles displaying the foot-and-mouth disease virus major antigenic site

Michèle Remond , Bruno B. da Costa , Sabine Riffault , Satya Parida , Emmanuel Breard et al.
Open Session of the Research Group of the European Commission for the Control of Foot-and-Mouth Disease (EUFMD), Oct 2008, Erice, Italy. 1 p., 2008
Poster de conférence hal-02816589 v1

Evaluation of a new vaccine candidate

Jean Francois J. F. Eleouet , Sabine Riffault
Colloque Eurobiotec, Oct 2008, Paris, France. 1 p., 2008
Poster de conférence hal-02813299 v1

A new subunit vaccine based on nucleocapsid protein nanoparticles confers partial protection in calves against respiratory syncytial virus

Sabine Riffault , Guillaume Durand , Marion Soulestin , Catherine C. Dubuquoy , Martine Deplanche et al.
2. Vaccine Congress, Dec 2008, Boston, United States. 1 p., 2008
Poster de conférence hal-02818104 v1

Pseudo-particules chimériques du virus de la bursite infectieuse aviaire (IBDV) exprimant le site antigénique majeur du virus de la fièvre aphteuse : études immunologiques

Michelle Rémond , Bruno B. da Costa , Sabine Riffault , Jean Lepault , Catherine C. Dubuquoy et al.
10. Journées Francophones de Virologie, Mar 2008, Paris, France. 1 p., 2008
Poster de conférence hal-02815198 v1

CD11b- CD8α- F4/80lo cells are the dominant CD11c+ subset found in lung of neonates: potential interest for antiviral vaccination

Xavier X. Roux , Catherine C. Dubuquoy , Bernard Charley , Sabine Riffault
Congrès Annuel de la Société Française d'Immunologie, Nov 2006, Paris, France. 1 p., 2006
Poster de conférence hal-02816756 v1

Etude des cellules dendritiques et macrophages du poumon : comparaison adultes nouveaux-nés

Xavier Roux , Catherine C. Dubuquoy , Bernard Charley , Sabine Riffault
Journées d’Animation Scientifique du Département de Santé Animale, 2005, Batz-sur-Mer, France. pp.Inconnu, 2005
Poster de conférence hal-02828241 v1

CD11b- CD8α- CD11c+ dendritic cells are the dominant subset found in lung of neonates: potential interest for antiviral vaccination

Xavier X. Roux , Catherine C. Dubuquoy , Bernard Charley , Sabine Riffault
4. European mucosal immunology group meeting, Oct 2004, Lyon, France. 1 p., 2004
Poster de conférence hal-02827063 v1