Sabine Riffault

Présentation

Neonatal sensitivity to respiratory viruses: how can we protect young animals against infections?

During the first months of life, acute lower respiratory tract infections are the major cause of morbidity and mortality among young mammals. The respiratory syncytial virus (RSV) is the main causative agent for broncho-pneumonia in calves (bovine RSV) and bronchiolitis in infants (human RSV). These viral infections have the particularity to cause severe acute lower respiratory disease in young animals whereas they are usually benign in adults, affecting only the upper respiratory tract. Thus, RSV infections are major health issues both for infants and calves. The neonatal period is characterized by immune responses quantitatively and qualitatively different from the adults one, issues that I have chosen to address through the following ongoing projects :

(a) To decipher the immunological and inflammatory mechanisms at stake in the lung upon respiratory infection of newborn.

(b) To elaborate new vaccine strategies against RSV using subunit vaccines: ring nanoparticles formed by the recombinant viral nucleoprotein and the pre-fusion form of the RSV fusion protein.

Publications

Article dans une revue (51)

Screening antivirals with a mCherry-expressing recombinant bovine respiratory syncytial virus: a proof of concept using cyclopamine Jenna Fix,Delphyne Descamps,Marie Galloux,Cécile Ferret,Edwige Bouguyonet al. Veterinary Research, 2023, 54 (1), pp.36. ⟨10.1186/s13567-023-01165-x⟩ Article dans une revue hal-04175283v1
La muqueuse pulmonaire en période périnatale : un monde à comprendre pour lutter contre la sensibilité du jeune à la bronchiolite Claire Chottin,Quentin Marquant,Vinciane Saint-Criq,Mark R. Thomas,Sabine Riffaultet al. Revue des Maladies Respiratoires, 2022, 39 (2), pp.104-107. ⟨10.1016/j.rmr.2022.01.012⟩ Article dans une revue hal-03625844v1
Longitudinal study of the immune response and memory following natural bovine respiratory syncytial virus infections in cattle of different age Sara Hägglund,Katarina Näslund,Anna Svensson,Cecilia Lefverman,Hakan Enület al. PLoS ONE, 2022, 17 (9), pp.e0274332. ⟨10.1371/journal.pone.0274332⟩ Article dans une revue hal-03800200v1
Le poumon est sensible aux effets locaux et à distance des microbiotes Elliot Mathieu,Quentin Marquant,Delphyne Descamps,Sabine Riffault,Vinciane Saint-Criqet al. Nutrition Clinique et Métabolisme, 2021, 35 (4), pp. 242-252. ⟨10.1016/j.nupar.2021.04.002⟩ Article dans une revue hal-03477849v1
Control of IFN-I responses by the aminopeptidase IRAP in neonatal C57BL/6 alveolar macrophages during RSV infection Carole Drajac,Daphné Laubreton,Quentin Marquant,Claire Chottin,Cécile Ferretet al. Mucosal Immunology, 2021, 14 (4), pp.949-962. ⟨10.1038/s41385-021-00402-w⟩ Article dans une revue hal-03244474v1
Hyper-Enriched Anti-RSV Immunoglobulins Nasally Administered: A Promising Approach for Respiratory Syncytial Virus Prophylaxis Emilie Jacque,Claire Chottin,Daphnée Laubreton,Michel Nogre,Cécile Ferretet al. Frontiers in Immunology, 2021, 12, pp.683902. ⟨10.3389/fimmu.2021.683902⟩ Article dans une revue hal-03287358v1
The microbiota plays a critical role in the reactivity of lung immune components to innate ligands Quentin Marquant,Daphné Laubreton,Carole Drajac,Elliot Mathieu,Edwige Bouguyonet al. FASEB Journal, 2021, 35 (4), 15 p. ⟨10.1096/fj.202002338R⟩ Article dans une revue hal-03169721v1
Single-Shot Vaccines against Bovine Respiratory Syncytial Virus (BRSV): Comparative Evaluation of Long-Term Protection after Immunization in the Presence of BRSV-Specific Maternal Antibodies Jean François Valarcher,Sara Hägglund,Katarina Näslund,Luc Jouneau,Ester Malmströmet al. Vaccines, 2021, 9 (3), 27 p. ⟨10.3390/vaccines9030236⟩ Article dans une revue hal-03182920v1
Regulatory B lymphocytes colonize the respiratory tract of neonatal mice and modulate immune responses of alveolar macrophages to RSV infection in IL-10-dependant manner Daphné Laubreton,Carole Drajac,Jean-François Eléouët,Marie Anne Rameix-Welti,Richard Lo-Manet al. Viruses, 2020, 12 (8), pp.822. ⟨10.3390/v12080822⟩ Article dans une revue hal-02938422v1
Michel Brémont (1953–2020) Stephane Biacchesi,Sabine Riffault,Thierry Pineau,Muriel Vayssier Taussat,Vincent Béringue Veterinary Research, 2020, 51 (1), pp.146. ⟨10.1186/s13567-020-00878-7⟩ Article dans une revue hal-03093574v1
The Role of Insulin Regulated Aminopeptidase in Endocytic Trafficking and Receptor Signaling in Immune Cells Delphyne Descamps,Irini Evnouchidou,Vivien Caillens,Carole Drajac,Sabine Riffaultet al. Frontiers in Molecular Biosciences, 2020, 7, ⟨10.3389/fmolb.2020.583556⟩ Article dans une revue (article de synthèse) hal-02972353v1
De novo protein design enables the precise induction of RSV-neutralizing antibodies Fabian Sesterhenn,Che Yang,Jaume Bonet,Johannes T. Cramer,Xiaolin Wenet al. Science, 2020, 368 (6492), ⟨10.1126/science.aay5051⟩ Article dans une revue hal-02677103v1
A single shot pre-fusion-stabilized bovine rsv f vaccine is safe and effective in newborn calves with maternally derived antibodies Sabine Riffault,Sara Hägglund,Efrain Guzman,Katarina Näslund,Luc Jouneauet al. Vaccines, 2020, 8 (2), 21 p. ⟨10.3390/vaccines8020231⟩ Article dans une revue hal-02677111v1
Boosting subdominant neutralizing antibody responses with a computationally designed epitope-focused immunogen Fabian Sesterhenn,Marie Galloux,Sabrina S Vollers,Lucia Csepregi,Che Yanget al. PLoS Biology, 2019, 17 (2), pp.e3000164. ⟨10.1371/journal.pbio.3000164⟩ Article dans une revue inserm-02138858v1
Paradigms of lung microbiota functions in health and disease, particularly, in asthma Elliot Mathieu,Unai Escribano-Vazquez,Delphyne Descamps,Claire Cherbuy,Philippe Langellaet al. Frontiers in Physiology, 2018, 9, pp.1-11. ⟨10.3389/fphys.2018.01168⟩ Article dans une revue (article de synthèse) hal-02627730v1
Proteome analysis of bronchoalveolar lavage from calves infected with bovine respiratory syncytial virus-Insights in pathogenesis and perspectives for new treatments Sara Hagglund,Krister Blodorm,Katarina Naslund,Karin Vargmar,Sara Bergstrom Lindet al. PLoS ONE, 2017, 12 (10), pp.1-19. ⟨10.1371/journal.pone.0186594⟩ Article dans une revue hal-02620701v1
Pulmonary susceptibility of neonates to respiratory syncytial virus infection: a problem of innate immunity? Carole Drajac,Daphnée Laubreton,Sabine Riffault,Delphyne Descamps Journal of Immunology Research, 2017, ⟨10.1155/2017/8734504⟩ Article dans une revue (article de synthèse) hal-02628884v1
RSV N-nanorings fused to palivizumab-targeted neutralizing epitope as a nanoparticle RSV vaccine Pierre Louis Hervé,Charlotte Deloizy,Delphyne Descamps,Marie-Anne Rameix Welti,Jenna J. Fixet al. Nanomedicine: Nanotechnology, Biology and Medicine, 2017, 13 (2), pp.411-420. ⟨10.1016/j.nano.2016.08.006⟩ Article dans une revue hal-02628338v1
Bacteria isolated from lung modulate asthma susceptibility in mice Aude Remot,Delphyne Descamps,Marie-Louise Noordine,Abdelhak Boukadiri,Elliot Mathieuet al. The International Society of Microbiologial Ecology Journal, 2017, pp.1061-1074. ⟨10.1038/ismej.2016.181⟩ Article dans une revue hal-01595509v1
Flt3 ligand improves the innate response to respiratory syncytial virus and limits lung disease upon RSV reexposure in neonate mice Aude Remot,Delphyne Descamps,Luc Jouneau,Daphnée Laubreton,Catherine Dubuquoyet al. European Journal of Immunology, 2016, 46 (4), pp.874-884. ⟨10.1002/eji.201545929⟩ Article dans une revue hal-01533877v1
Non-invasive epicutaneous vaccine against Respiratory Syncytial Virus: Preclinical proof of concept Pierre-Louis Hervé,Delphyne Descamps,Charlotte Deloizy,Véronique Dhelft,Daphné Laubretonet al. Journal of Controlled Release, 2016, 243, pp.146-159. ⟨10.1016/j.jconrel.2016.10.003⟩ Article dans une revue hal-01425790v1
A bovine respiratory syncytial virus model with high clinical expression in calves with specific passive immunity Krister Blodorn,Sara Hagglund,Dolores Gavier-Widén,Jean Francois J. F. Eleouet,Sabine Riffaultet al. BMC Veterinary Research, 2015, 11, ⟨10.1186/s12917-015-0389-6⟩ Article dans une revue hal-02640254v1
Visualizing the replication of respiratory syncytial virus in cells and in living mice Marie-Anne Rameix-Welti,Ronan Le Goffic,Pierre-Louis Hervé,Julien Sourimant,Aude Remotet al. Nature Communications, 2014, 5, ⟨10.1038/ncomms6104⟩ Article dans une revue hal-02633568v1
Characterization of an experimental vaccine for bovine respiratory syncytial virus Sara Hagglund,Kefei Hu,Krister Blodorn,Boby Makabi-Panzu,Anne-Laure Gaillardet al. Clinical and Vaccine Immunology, 2014, 21 (7), pp.997-1004. ⟨10.1128/CVI.00162-14⟩ Article dans une revue hal-01204394v1
Vaccine Safety and Efficacy Evaluation of a Recombinant Bovine Respiratory Syncytial Virus (BRSV) with Deletion of the SH Gene and Subunit Vaccines Based On Recombinant Human RSV Proteins: N-nanorings, P and M2-1, in Calves with Maternal Antibodies Krister Blodorn,Sara Hagglund,Jenna J. Fix,Catherine C. Dubuquoy,Boby Makabi-Panzuet al. PLoS ONE, 2014, 9 (6), ⟨10.1371/journal.pone.0100392⟩ Article dans une revue hal-02639198v1
A Novel Subnucleocapsid Nanoplatform for Mucosal Vaccination against Influenza Virus That Targets the Ectodomain of Matrix Protein 2 Pierre-Louis Hervé,Mariam Raliou,Christiane Bourdieu,Catherine C. Dubuquoy,Agnes Petit-Camurdanet al. Journal of Virology, 2014, 88 (1), pp.325-338. ⟨10.1128/JVI.01141-13⟩ Article dans une revue hal-02637841v1
Mucosal Imprinting of Vaccine-Induced CD8(+) T Cells Is Crucial to Inhibit the Growth of Mucosal Tumors Federico Sandoval,Magali Terme,Mevyn Nizard,Cecile Badoual,Michel-Francis Bureauet al. Science Translational Medicine, 2013, 5 (172), ⟨10.1126/scitranslmed.3004888⟩ Article dans une revue hal-02650685v1
Nucleoprotein nanostructures combined with adjuvants adapted to the neonatal immune context: a candidate mucosal RSV vaccine Aude A. Remot,Xavier X. Roux,Catherine C. Dubuquoy,Jenna J. Fix,Stephan S. Bouetet al. PLoS ONE, 2012, 7 (5), Non paginé. ⟨10.1371/journal.pone.0037722⟩ Article dans une revue hal-01001405v1
Neonatal lung immune responses show a shift of cytokines and transcription factors toward Th2 and a deficit in conventional and plasmacytoid dendritic cells Xavier X. Roux,Aude A. Remot,Agnes A. Petit Camurdan,Marie-Anne Nahori,Helene Kiefer-Biasizzoet al. European Journal of Immunology, 2011, 41 (10), pp.2852-2861. ⟨10.1002/eji.201041224⟩ Article dans une revue hal-02644846v1
A new subunit vaccine based on nucleoprotein nanoparticles confers partial clinical and virological protection in calves against bovine respiratory syncytial virus Sabine Riffault,Gilles G. Meyer,Martine Deplanche,Catherine C. Dubuquoy,Guillaume Durandet al. Vaccine, 2010, 28 (21), pp.3722-3734. ⟨10.1016/j.vaccine.2010.03.008⟩ Article dans une revue hal-02658778v1
Protective Role for Protease-Activated Receptor-2 against Influenza Virus Pathogenesis via an IFN-gamma-Dependent Pathway Khaled Khoufache,Fanny Lebouder,Eric E. Morello,Fabrice Laurent,Sabine Riffaultet al. Journal of Immunology, 2009, 182 (12), pp.7795-7802. ⟨10.4049/jimmunol.0803743⟩ Article dans une revue hal-02663202v1
Infectious bursal disease subviral particles displaying the foot-and-mouth disease virus major antigenic site Michelle Rémond,Bruno B. da Costa,Sabine Riffault,Satya Parida,Emmanuel Breardet al. Vaccine, 2009, 27 (1), pp.93-98. ⟨10.1016/j.vaccine.2008.10.036⟩ Article dans une revue istex hal-02664065v1
Plasmacytoid dendritic cells migrate in afferent skin lymph Florentina Pascale,Vanessa Contreras,Michel Bonneau,Alexandre Courbet,Stefan Chilmonczyket al. Journal of Immunology, 2008, 180 (9), pp.5963-5972. ⟨10.4049/jimmunol.180.9.5963⟩ Article dans une revue hal-01193693v1
Sub-nucleocapsid nanoparticles: a nasal vaccine against respiratory syncytial virus Xavier X. Roux,Catherine C. Dubuquoy,Guillaume Durand,Thi-Lan Tran-Tolla,Nathalie Castagnéet al. PLoS ONE, 2008, 3 (3), pp.e1766. ⟨10.1371/journal.pone.0001766⟩ Article dans une revue hal-02655935v1
Recombinant rotavirus inner core proteins produced in the milk of transgenic rabbits confer a high level of protection after intrarectal delivery. Eric Soler,Nathalie Parez,Bruno Passet,Catherine Dubuquoy,Sabine Riffaultet al. Vaccine, 2007, 25 ((34)), pp.6373-80. ⟨10.1016/j.vaccine.2007.06.011⟩ Article dans une revue istex hal-00815843v1
Efficacy of particle-based DNA delivery for vaccination of sheep against FMDV V. Niborski,Y. Li,Fiona Brennan,M. Lane,A.M. Torchéet al. Vaccine, 2006, 24 (49-50), pp.7204-7213. ⟨10.1016/j.vaccine.2006.06.048⟩ Article dans une revue istex hal-02658133v1
Porcine innate and adaptative immune responses to influenza and coronavirus infections Bernard Charley,Sabine Riffault,Kristien van Reeth Annals of the New York Academy of Sciences, 2006, 1081 (1), pp.130-136. ⟨10.1196/annals.1373.014⟩ Article dans une revue hal-02662172v1
Replication of Bovine respiratory syncytial virus in murine cells depends on type I interferon-receptor functionality Sabine Riffault,Catherine C. Dubuquoy,Nathalie Castagné,Eric Baranowski,Bernard Charleyet al. Journal of General Virology, 2006, 87 (8), pp.2145-2148. ⟨10.1099/vir.0.82091-0⟩ Article dans une revue hal-02661692v1
Antigen presenting cells in mucosal sites of veterinary species Karin Haverson,Sabine Riffault Veterinary Research, 2006, 37 (3), pp.339-358. ⟨10.1051/vetres:2006005⟩ Article dans une revue hal-00903028v1
Migratory monocytes and granulocytes are major lymphatic carriers of Salmonella from tissue to draining lymph node Michel M. Bonneau,Mathieu Epardaud,Fabrice Payot,Violeta Niborski,Marie-Isabelle Thoulouzeet al. Journal of Leukocyte Biology, 2006, 79, pp.268-276. ⟨10.1189/jlb.0605288⟩ Article dans une revue hal-02666924v1
TLR9 pathway is involved in adjuvant effects of plasmid DNA-based vaccines Daniela Tudor,Catherine C. Dubuquoy,Valérie Gaboriau,Francois F. Lefèvre,Bernard Charleyet al. Vaccine, 2005, 23 (10), pp.1258-1264. ⟨10.1016/j.vaccine.2004.09.001⟩ Article dans une revue istex hal-02680528v1
Type I IFN modulates the immune response induced by DNA vaccination to pseudorabies virus glycoprotein C D. Tudor,Sabine Riffault,C. Carrat,Francois F. Lefèvre,Marielle Bernoinet al. Virology, 2001, 286, pp.197-205 Article dans une revue hal-02671713v1
Interferon-alpha-producing cells are localized in gut-associated lymphoid tissues in transmissible gastroenteritis virus (TGEV) infected piglets Sabine Riffault,C. Carrat,K. van Reeth,M. Pensaert,Bernard Charley Veterinary Research, 2001, 32 (1), pp.71-79 Article dans une revue hal-02681357v1
Interferon-alpha-producing cells are localized in gut-associated lymphoid tissues in transmissible gastroenteritis virus (TGEV) infected piglets Sabine Riffault,Charles Carrat,Kristien van Reeth,Maurice Pensaert,Bernard Charley Veterinary Research, 2001, 32 (1), pp.71-79. ⟨10.1051/vetres:2001111⟩ Article dans une revue hal-00902690v1
Transient IFN-gamma synthesis in the lymph node draining a dermal site loaded with UV-irradiated herpes simplex virus type 1 : an NK- and CD3-dependent process regulated by IL-12 but not by IFN-alpha/beta Sabine Riffault,C. Carrat,G. Milon,Bernard Charley,J.H. Colle Journal of General Virology, 2000, 81, pp.2365-2373 Article dans une revue hal-02692065v1
Vesicular stomatitis virus and pseudorabies virus induce a vig 1/cig5 homologue in mouse dendritic cells via different pathways Pierre Boudinot,Sabine Riffault,S. Salhi,C. Carrat,C. Sedliket al. Journal of General Virology, 2000, 81, pp.2675-2682 Article dans une revue hal-02695563v1
vig-1, a new fish gene induced by the rhabdovirus glycoprotein, has a virus-induced homologue in humans and shares conserved motifs with the MoaA family Pierre Boudinot,Pascale Massin,Mar Blanco,Sabine Riffault,Abdenour Benmansour Journal of Virology, 1999, 73 (3), pp.1846-1852 Article dans une revue hal-02697891v1
In vivo induction of interferon-alpha in pig by non-infectious coronavirus: tissue localization and in situ phenotypic characterization of interferon-alpha-producing cells Sabine Riffault,C. Carrat,Lydia Besnardeau,Claude La Bonnardière,Bernard Charley Journal of General Virology, 1997, 78, pp.2483-2487 Article dans une revue hal-02687594v1
Reconstituted coronavirus TGEV virosomes lose the virus ability to induce porcine interferon-alpha production Sabine Riffault,J Grosclaude,Muriel Vayssier Taussat,H Laude,B Charley Veterinary Research, 1997, 28 (1), pp.77-86 Article dans une revue hal-00902460v1
Reconstituted coronavirus TGEV virosomes lose the virus ability to induce porcine interferon-alpha production Sabine Riffault,Jeanne Grosclaude,Muriel Vayssier Taussat,Hubert Laude,Bernard Charley Veterinary Research, 1997, 28 (2), pp.105-114 Article dans une revue hal-02685172v1
Herpes simplex virus induces appearance of interferon-alpha/bêta-producing cells and partially interferon-alpha/bêta-dependent accumulation of leukocytes in murine regional lymph nodes Sabine Riffault,M.L. Eloranta,C. Carrat,K. Sandberg,Bernard Charleyet al. Journal of Interferon and Cytokine Research, 1996, 16, pp.1007-1014 Article dans une revue hal-02690475v1

Communication dans un congrès (38)

The cytokine response to innate stimuli in blood of calves at birth and the occurrence of infectious diarrhoea Sabine Riffault,Delphyne Descamps,Delphyne Descamps,Cécile Ferret,Cécile Ferretet al. 8th European Veterinary Immunology Workshop, European Federation of Immunological Societies, Sep 2024, Dublin, Ireland Communication dans un congrès hal-05298008v1
Evaluation de la compétence immunitaire innée chez des veaux en période périnatale, en relation avec l’occurence de diarrhées Sabine Riffault,Luc Jouneau,Denis Laloë,Aurélie Vinet,Rachel Lefebvreet al. Symposium du Club d'Immunologie et Vaccinologie Vétérinaires (CIVVet), May 2023, Toulouse, France Communication dans un congrès hal-04186459v1
Comparaison des signatures cytokiniques innées des compartiments pulmonaire et sanguin chez le veau Cécile Ferret,Florence Carreras,Claire Chottin,Luc Jouneau,Sonia Lacroix-Lamandéet al. Symposium du Club d’Immunologie et Vaccinologie Vétérinaires (CIVVet), May 2023, Toulouse, France Communication dans un congrès hal-04186480v1
Identification de régions du génome et de gènes candidats associés au niveau de réponse immune innée de veaux Holstein Pauline Martin,Luc Jouneau,Sébastien Taussat,Aurélie Vinet,Rachel Lefebvreet al. ​26. Rencontres autour des Recherches sur les Ruminants, Institut de l'élevage [IDELE]; INRAE, Dec 2022, Paris, France. pp.187-190 Communication dans un congrès hal-04033238v1
Identification of genome regions and promising candidate genes linked to innate immune capacity on young Holstein calves P Martin,S Fresco,L Jouneau,S Taussat,A Vinetet al. 12th World Congress on Genetics Applied to Livestock Production, Jul 2022, Rotterdam, Netherlands. ⟨10.15454/1.5483257052131956E12⟩ Communication dans un congrès hal-03731335v1
Immunomodulation strategy against Respiratory Syncytial Virus infection by using lung primo-colonizing bacteria Claire Chottin,Quentin Marquant,Vinciane Saint-Criq,Daphne Laubreton,Carole Drajacet al. 12th International RSV Symposium (RSV2022), Sep 2022, Belfast (Northern Ireland), United Kingdom Communication dans un congrès hal-05303039v1
Efficacy of subunit BRSV vaccines in calves : towards a translational model for infant vaccination? Sabine Riffault 7th European Veterinary Immunology Workshop (EVIW), European Veterinary Immunology Group (EVIG), Aug 2021, Virtual format, Serbia Communication dans un congrès hal-04466713v1
Microbiota educates innate immune response to Toll-like receptors ligands and RSV infection in lung Quentin Marquant,Daphné Lebreton,Carole Drajac,Elliot Mathieu,Marie-Louise Noordineet al. international congress ERS, European Respiratory Society, Oct 2019, Madrid, Spain Communication dans un congrès hal-04295177v1
Bacteria isolated from lung as biotherapeutics in asthma. Aude Remot,Jennifer Palomo,Alexandre David-Hachette,Elliot Mathieu,Delphyne Descampset al. international congress ERS, European Respiratory Society, Sep 2019, Madrid, Spain Communication dans un congrès hal-04295043v1
Driving immune responses with synthetic proteins - development of de novo designed immunogens to elicit respiratory syncytial virus neutralizing antibodies Fabian Sesterhenn,Che Yang,Jaume Bonet,Marie Galloux,Xiaolin Wenet al. 32nd Annual Symposium of the Protein-Society, Protein Society. USA. Beckman Coulter Inc, USA. Pall ForteBio, USA. Bristol-Myers Squibb (BMS), USA., Jul 2018, Boston, United States. pp.2 Communication dans un congrès hal-02734561v1
Preclinicalevaluation of anovel non-Invasive epicutaneous vaccine against respiratory syncytial virus Pierre-Louis Hervé,Delphyne Descamps,Charlotte Deloizy,Veronique Dhelft,Daphne Laubretonet al. Annual Meeting of the American-Academy-of-Allergy-Asthma-and-Immunology, Mar 2017, Atlanta, Georgia. pp.1 Communication dans un congrès hal-01605167v1
Respiratory syncytial virus targets a fetally developed B cell population with regulatory functions which predicts disease severity D. Zhivaki,S. Lemoine,M. -A Rameix-Welti,A. Lim,Delphyne Descampset al. International Congress of Immunology (ICI), Aug 2016, Melbourne, Australia. pp.1 Communication dans un congrès hal-02742028v1
Impact of the development of the lung microbiota on neonatal immunity Aude Remot,Marie-Louise M.-L. Noordine,Chantal C. Bridonneau,Delphyne Descamps,Sabine Riffaultet al. 20. Colloque du Club des Bactéries Lactiques, Jun 2015, Lille, France Communication dans un congrès hal-02742693v1
Lung neonatal responses to respiratory syncytial virus reveal deficiencies in dendritic cells and type I interferon in a mouse model of airway enhanced disease Aude Remot,Luc Jouneau,Delphyne Descamps,Catherine C. Dubuquoy,Stephan S. Bouetet al. 8. Word Immune Regulation Meeting, Mar 2014, Davos, Switzerland Communication dans un congrès hal-02740120v1
A novel proteic nano-platform for antigens: application to musocal influenza vaccination. Mariam Raliou,Pierre-Louis Hervé,Christophe Chevalier,Christiane Bourdieu,Catherine Dubuquoyet al. VIRUS-LIKE PARTICLE & NANO-PARTICLE VACCINES, Nov 2012, Cannes, France Communication dans un congrès hal-01191379v1
Adapting vaccine formulation to the neonatal context is required to obtain safe protection against the respiratory syncytial virus Aude Remot,Xavier Roux,Catherine Dubuquoy,Julie Bernard,Mohammed Moudjouet al. European Congress of Immunology, Sep 2012, Glasgow, Scotland, United Kingdom. pp.727 Communication dans un congrès hal-01003266v1
A novel proteic nano-platform for antigens: application to mucosal influenza vaccination. Sabine Riffault 2eme séminaire du département de microbiologie de IRBA, 2012, Paris, France Communication dans un congrès hal-02744447v1
Transcriptomic analysis of neonatal vs. adult lung early responses to RSV reveals key roles for DC and type I IFN in controlling immunopathologic imprinting. Aude Remot,Luc Jouneau,Catherine Dubuquoy,Stephan Bouet,Jérôme Lecardonnelet al. Diversity and plasticity of DCs, Dec 2012, Paris, France Communication dans un congrès hal-01191380v1
Newborns are particularly prone to respiratory syncytial virus infection: why ? How to protect them ? Aude Remot,Agnes A. Petit Camurdan,Catherine C. Dubuquoy,Julie Bernard,Mohammed M. Moudjouet al. Journées d'Animation Scientifique du Département Santé Animale, May 2011, Fréjus, France. 130 p Communication dans un congrès hal-02744806v1
Which immune lung features relate to the higher severity of respiratory syncytial virus infection in newborns? Aude Remot,Sabine Riffault Séminaire, Institute for Virology, University of veterinary medicine, Sep 2010, Hannovre, Germany Communication dans un congrès hal-02813237v1
Vaccination of newborn mice with the nucleoprotein of human RSV confers viral protection but enhances pulmonary inflammation after challenge Agnes A. Petit Camurdan,Catherine C. Dubuquoy,Julie Bernard,Jean Francois J. F. Eleouet,Sabine Riffault Journées d'Animation Scientifique du Département Santé Animale, May 2009, Port d'Albret, France Communication dans un congrès hal-02752386v1
A New Subunit Vaccine Based on Nucleocapsid Protein Nanoparticles Confers Partial Protection in Calves Against Respiratory Syncytial Virus Sabine Riffault,Gilles G. Meyer,Guillaume Durand,Marion Soulestin,Catherine C. Dubuquoyet al. 3. European Veterinary Immunology Workshop EVIW, Sep 2009, Berlin, Germany. n.p Communication dans un congrès hal-02824159v1
Protective role for Protease-Activated-Receptor-2 against Influenza virus Pathogenesis via an Interferon-Y dependent pathway Khaled Khoufache,Fanny Le Bouder,Eric E. Morello,Fabrice Laurent,Sabine Riffaultet al. Journées d'animation scientifique du Département Santé Animale, May 2009, Port d'Albret, France Communication dans un congrès hal-02755857v1
Plasmacytoid dendritic cells migrate in afferent skin and oro-nasal lymph Florentina Pascale,Alexandre Courbet,Michel M. Bonneau,Violeta Niborski,Mathieu Epardaudet al. Réunion de la Société Française d'Immunologie et Club Francophone des Cellules Dendritiques, Jun 2008, Paris, France. n.p Communication dans un congrès hal-02818326v1
Une nouvelle stratégie vaccinale contre le virus respiratoire syncytial, basée sur des assemblages nanoparticulaires de la protéine de nucléocapside Sabine Riffault,Agnes A. Petit Camurdan,Xavier X. Roux,Catherine C. Dubuquoy,Guillaume Durandet al. 10. Journées Francophones de Virologie, Mar 2008, Paris, France. n.p Communication dans un congrès hal-02815443v1
A New Subunit Vaccine Based on Nucleocapsid Protein Nanoparticles Confers Protection Against Respiratory Syncytial Virus Sabine Riffault,Guillaume Durand,Marion Soulestin,Catherine C. Dubuquoy,Martine Deplancheet al. Réunion du Club de Vaccinologie de la Société Française d'Immunologie, Nov 2008, Paris, France. n.p Communication dans un congrès hal-02815657v1
Evaluation of a new respiratory syncytial virus vaccine candidate Gilles G. Meyer,Martine Deplanche,Catherine C. Dubuquoy,Marion Soulestin,Guillaume Durandet al. 25. World Buiatrics Congress, Jul 2008, Budapest, Hungary. n.p Communication dans un congrès hal-02822661v1
Evaluation dans l'espèce cible d'une nouvelle stratégie vaccinale contre le virus respiratoire syncytial bovin, basée sur des assemblages nanoparticulaires de la protéine de nucléocapside Sabine Riffault,Guillaume Durand,Marion Soulestin,Catherine C. Dubuquoy,Nathalie Castagnéet al. Journée d'Animation du Réseau Immunologie des Animaux Domestiques (IAD), Nov 2007, Montpellier, France. n.p Communication dans un congrès hal-02823927v1
La vaccination nasale avec la nucléoprotéine du virus respiratoire syncytial confère une immunité protectrice contre une épreuve virale Xavier X. Roux,Agnes A. Petit Camurdan,Catherine C. Dubuquoy,Guillaume Durand,Nathalie Castagnéet al. Journées d'Animation Scientifique du Département de Santé Animale, Jun 2007, Tours, France Communication dans un congrès hal-02752791v1
Type I interferon producing cells (ipc) can gain lymph nodes via the afferent lymphatic route Florentina Pascale,Vanessa Contreras,Alexandre Courbet,Michel Bonneau,Stefan Chilmonczyket al. 13. International Congress of Immunology, Aug 2007, Rio de Janeiro, Brazil. 1 p Communication dans un congrès hal-01193698v1
Plasmacytoid DC migrate in afferent lymph Club Francophone des cellules dendritiques Florentina Pascale,Alexandre Courbet,Michel M. Bonneau,Celine C. Urien,Catherine C. Dubuquoyet al. Congrès annuel de la Société Française d'Immunologie (SFI), Nov 2007, Lyon, France. n.p Communication dans un congrès hal-02819602v1
Mucosal vaccination with the nucleoprotein of respiratory syncytial virus confers protective immunity Xavier Roux,Catherine C. Dubuquoy,Nathalie Castagné,Julie Bernard,Jean Francois J. F. Eleouetet al. Congrès Européen d'Immunologie des Muqueuses (EMIG), Oct 2006, Paris, France. n.p Communication dans un congrès hal-02814536v1
Natural Interferon (IFN) producing cells can reach lymph node via afferent lymph Florentina Pascale,Alexandre Courbet,Michel M. Bonneau,Celine C. Urien,Catherine C. Dubuquoyet al. 2. European Veterinary Immunology Workshop, Sep 2006, Paris, France. n.p Communication dans un congrès hal-02818733v1
Porcine innate and adaptative immune responses to influenza and coronavirus infections Bernard Charley,Sabine Riffault,Kristien van Reeth 8. Conference of the Society for Tropical Veterinary Medicine, Jun 2005, Hanoi, Vietnam. n.p Communication dans un congrès hal-02831435v1
Etude des cellules dendritiques et macrophages du poumon : comparaison adultes nouveaux-nés Xavier X. Roux,Catherine C. Dubuquoy,Bernard Charley,Sabine Riffault Journées d'Animation Scientifique du Département de Santé Animale, May 2005, Batz-sur-Mer, France Communication dans un congrès hal-02759410v1
Particle-based DNA vaccination against Foot-and-Mouth disease is efficient in sheep Violeta Niborski,Y. Li,C. Stirling,Fiona Brennan,A.M. Torchéet al. Rencontres du Réseau français d'Immunologie des Animaux Domestiques (IAD), Oct 2005, Lyon, France. n.p Communication dans un congrès hal-02832501v1
Etude des bases moléculaires de la spécificité d’espèce du VRS et essais de développement d’un modèle murin pour le VRS bovin Jean Francois J. F. Eleouet,Nathalie Castagné,Eric E. Baranowski,Martine Deplanche,Gilles G. Meyeret al. Séminaire bilan du programme de recherche Zoonoses, Sep 2004, Nouzilly, France. n.p Communication dans un congrès hal-02832498v1
Cellules sécrétrices d'IFN alpha dans le tissu lymphoïde associé à la muqueuse intestinale du porcelet infecté par le virus GET Sabine Riffault,C. Carrat,M. Enache,K. van Reeth,M. Pensaertet al. Immunité muqueuse, Jun 1999, Toulouse, France Communication dans un congrès hal-02770429v1

Poster de conférence (26)

Signatures immuno-metabolomiques des cellules immunitaires innées bovines Aude Remot,Guillaume Sallé,Cécile Ferret,Ambre Baillou,Mégane Fernandezet al. Symposium Club d’Immunologie et Vaccinologie Vétérinaire (CIVVet), May 2023, Toulouse, France Poster de conférence hal-04186688v1
Immunostimulation of bovine neonate immune cells : metabolomic and transcriptomic responses Aude Remot,Guillaume Sallé,Cécile Ferret,Mégane Fernandez,Florence Carreraset al. Journées d'animation scientifique du département Santé Animale (JAS SA), Oct 2022, Anglet, France Poster de conférence hal-04172281v1
Microbiota impacts the susceptibility of the airway inflammatory responses Delphyne Descamps,Sabine Riffault Journée de la recherche respiratoire, Oct 2021, Brest, France Poster de conférence hal-04208426v1
Immunomodulation de la sensibilité néonatale au Virus Respiratoire Syncytial: Vers une approche thérapeutique basée sur des bactéries primo-colonisatrices du poumon Quentin Marquant,Daphné Laubreton,Carole Drajac,Elliot Mathieu,Edwige Bouguyonet al. Vaincre la mucoviscidose, Feb 2020, Paris, France Poster de conférence halshs-04172975v1
BACTERIA ISOLATED FROM LUNG AS BIOTHERAPEUTICS IN ASTHMA Elliot Mathieu,Jennifer Palomo,Alexandre David-Hachette,Quentin Marquant,Aude Remotet al. international congress ERS, Sep 2019, Madrid, Spain Poster de conférence hal-04295216v1
Microbiota impacts the susceptibility of the airway inflammatory responses Delphyne Descamps,Sabine Riffault,Muriel Thomas,Quentin Marquant European Respiratory Society, Sep 2019, Madrid, Spain Poster de conférence hal-04208429v1
Control of nonatal type I interferon responses by IRAP upon RSV infection Carole Drajac,Daphnée Laubreton,Loredana Saveanu,Sabine Riffault,Delphyne Descamps IRAP 2017, 3rd international symposium, 2017, Paris, France. 2017 Poster de conférence hal-01605602v1
Lung neonatal responses to respiratory syncytial virus reveal deficiencies in dendritic cells and type I interferon in a mouse model of airway enhanced disease Aude Remot,Delphyne Descamps,Luc Jouneau,Catherine C. Dubuquoy,Stephan S. Bouetet al. 13. International Symposium on Dendritic Cells, Sep 2014, Tours, France. 2014 Poster de conférence hal-02739158v1
Impact of the development of the pulmonary microbiota on neonatal immunity Aude Remot,Alix Penel,Mathilde Bauducel,Chantal C. Bridonneau,Delphyne Descampset al. 8. Word Immune Regulation Meeting, Mar 2014, Davos, Switzerland. 2014 Poster de conférence hal-02742629v1
Impact of the development of the pulmonary microbiota on neonatal immunity Aude Remot,Alix Penel,Mathilde Bauducel,Chantal C. Bridonneau,Delphyne Descampset al. AgreenSkills Annual Meeting 2013, Nov 2013, Louvain, Belgium. 87 p., 2013 Poster de conférence hal-02748060v1
Recombinant hRSV expressing mCherry or luciferase without fitness alteration Marie-Anne Rameix-Welti,Julien Sourimant,Jenna J. Fix,Aude Remot,Sabine Riffaultet al. 14. International Negative Strand Virus Meeting, Jun 2013, Granada, Spain. , 2013 Poster de conférence hal-02744494v1
Transcriptomic analysis of neonatal vs. adult lung early responses to RSV reveals key roles for DC and type I IFN in controlling immunopathologic imprinting Aude Remot,Luc Jouneau,Catherine Dubuquoy,Stephan S. Bouet,Jerome Lecardonnelet al. Diversity and plasticity of DCs, Club Francophone des Cellules Dendritiques, Dec 2012, Paris, France Poster de conférence hal-02935313v1
Age-related differences in the lung tissue susceptibility to Respiratory Syncytial Virus Aude A. Remot,Azadeh Djavidi,Catherine C. Dubuquoy,Isabelle Schwartz-Cornil,Fabrice Laurentet al. 4. European Veterinary Immunology Workshop (EVIW), Sep 2012, Edimbourg, United Kingdom. 2012 Poster de conférence hal-02748020v1
Neonatal Nasal Vaccination with the Nucleoprotein of the Respiratory Syncytial Virus Elicits Virus-protective but Airway-pathogenic Th2-biased Immunity that can be Modulated by the Choice of Adjuvants Aude Remot,Xavier X. Roux,Catherine C. Dubuquoy,Julie Bernard,Mohammed M. Moudjouet al. 15. International Congress of Mucosal Immunology (ICMI 2011) "Peace and War at Mucosal Surfaces", Jul 2011, Paris, France. , 2011 Poster de conférence hal-02745248v1
Nucleoprotein nanostructures: a mucosal subunit vaccine candidate for neonates protective against the respiratory syncytial virus Aude Remot,Xavier X. Roux,Catherine C. Dubuquoy,Julie Bernard Theron,Jenna J. Fixet al. Journées de l’Ecole doctorale ABIES, Mar 2011, Paris, France. 2011 Poster de conférence hal-02805147v1
Nucleoprotein nanostructures: a mucosal subunit vaccine candidate for neonates protective against the respiratory syncytial virus Aude Remot,Xavier X. Roux,Catherine C. Dubuquoy,Julie Bernard Theron,Jenna J. Fixet al. Cold spring Harbor meeting: Harnessing immunity to treat and prevent diseases, Nov 2011, New York, United States. 79 p., 2011 Poster de conférence hal-02745116v1
Rôle des récepteurs PAR et TLR pulmonaires dans les réponses néonatales aux infections virales respiratoires Aude Remot,Azadeh Djavidi,Agnes Petit-Camurdan,Catherine C. Dubuquoy,Isabelle Schwartz-Cornilet al. 6. Colloque DOC’J 2010 "La biologie et les sciences qui gravitent autour d'elle", May 2010, Jouy-en-Josas, France. , 2010 Poster de conférence hal-02754675v1
Vaccination of newborn mice with the nucleoprotein of human RSV confers viral protection but enhances pulmonary inflammation after challenge A Petit-Camurdan,Catherine C. Dubuquoy,Julie Bernard,Jf Eléouët,Sabine Riffault Journées d’Animation Scientifique du Département Santé Animale, 2009, Port d'Albret, France. pp.Inconnu, 2009 Poster de conférence hal-02815224v1
Protective role for Protease-Activated-Receptor-2 against Influenza virus Pathogenesis via an Interferon-Y dependent pathway Khaled Khoufache,F Lebouder,Eric Morello,Fabrice Laurent,Sabine Riffaultet al. Journées d’Animation Scientifique du Département Santé Animale, 2009, Port d'Albret, France. pp.Inconnu, 2009 Poster de conférence hal-02815269v1
Infectious bursal disease subviral particles displaying the foot-and-mouth disease virus major antigenic site Michèle Remond,Bruno B. da Costa,Sabine Riffault,Satya Parida,Emmanuel Breardet al. Open Session of the Research Group of the European Commission for the Control of Foot-and-Mouth Disease (EUFMD), Oct 2008, Erice, Italy. 1 p., 2008 Poster de conférence hal-02816589v1
Evaluation of a new vaccine candidate Jean Francois J. F. Eleouet,Sabine Riffault Colloque Eurobiotec, Oct 2008, Paris, France. 1 p., 2008 Poster de conférence hal-02813299v1
Pseudo-particules chimériques du virus de la bursite infectieuse aviaire (IBDV) exprimant le site antigénique majeur du virus de la fièvre aphteuse : études immunologiques Michelle Rémond,Bruno B. da Costa,Sabine Riffault,Jean Lepault,Catherine C. Dubuquoyet al. 10. Journées Francophones de Virologie, Mar 2008, Paris, France. 1 p., 2008 Poster de conférence hal-02815198v1
A new subunit vaccine based on nucleocapsid protein nanoparticles confers partial protection in calves against respiratory syncytial virus Sabine Riffault,Guillaume Durand,Marion Soulestin,Catherine C. Dubuquoy,Martine Deplancheet al. 2. Vaccine Congress, Dec 2008, Boston, United States. 1 p., 2008 Poster de conférence hal-02818104v1
CD11b- CD8α- F4/80lo cells are the dominant CD11c+ subset found in lung of neonates: potential interest for antiviral vaccination Xavier X. Roux,Catherine C. Dubuquoy,Bernard Charley,Sabine Riffault Congrès Annuel de la Société Française d'Immunologie, Nov 2006, Paris, France. 1 p., 2006 Poster de conférence hal-02816756v1
Etude des cellules dendritiques et macrophages du poumon : comparaison adultes nouveaux-nés Xavier Roux,Catherine C. Dubuquoy,Bernard Charley,Sabine Riffault Journées d’Animation Scientifique du Département de Santé Animale, 2005, Batz-sur-Mer, France. pp.Inconnu, 2005 Poster de conférence hal-02828241v1
CD11b- CD8α- CD11c+ dendritic cells are the dominant subset found in lung of neonates: potential interest for antiviral vaccination Xavier X. Roux,Catherine C. Dubuquoy,Bernard Charley,Sabine Riffault 4. European mucosal immunology group meeting, Oct 2004, Lyon, France. 1 p., 2004 Poster de conférence hal-02827063v1