Sandrine Auger

Présentation

Etude de la régulation de l’expression génétique et de l’adaptation du métabolisme bactérien en réponse à des variations environnementales : de la microbiologie expérimentale à la bioinformatique intégrative.

Projets de recherche

2018-Diversité des souches de F. prausnitzii dans le microbiote intestinalhumain.

Responsable de la tâche bioinformatique WP1.2 dans le projet Carnot-Qualiment BP Acetate coordonné par E. Huillet. &quot;Développement de co-cultures bactériennes pour

potentialiser la biomasse et les effets santé de bactéries intestinales anaérobie strictes&quot;.

2017-2018Impact de la réponse nitrogène sur les bactéries du microbiote intestinal humain.

2010-2017 Interconnexions des réseaux de régulation de voies métaboliques chez B. subtilis.

Responsable de la tâche WP6 dans le programme Marie Curie Initial Training Network FP7/2012 AMBER coordonné par L. Hamoen. &quot;Central carbon metabolism and main cellular processes in B. subtilis&quot;. 2013-2016.

Participation au projet européen BaSyntheccoordonné par P. Noirot. &quot;Bacterial Synthetic minimal genomes for biotechnology&quot;. 2010-2013

Participation au projet européen BaSysBio coordonné par P. Noirot. &quot;Towards an understanding of dynamic transcriptional regulation at global scale in bacteria: a systems biology approach&quot;. 2010-2011

2005-2009 Evolution des génomes au sein du groupe B. cereus.

Participation au projet national PNRA B. cereus coordonné par C. Nguyen. &quot;Nouvelle approche et nouveaux outils pour étudier l’émergence d’une bactérie pathogène dans les filières alimentaires. Le cas de B. cereus dans les produits non stériles traités thermiquement&quot;. 2005-2008

2003-2005 Formation de biofilms par B. cereus sur substrats inertes.

1999-2003 Caractérisation de gènes impliqués dans le métabolisme du soufre chez B. subtilis.

Publications

Article dans une revue (48)

Cobalamin-mediated protection of Faecalibacterium duncaniae against oxidative stress: Insights from proteomic and membrane fatty acid profiles Maria Alejandra de Angel Fontalvo,Simon Ménard,Rime Chebbo,Jasmina Vidic,Alban Amoroset al. Microbiological Research, 2026, 306, pp.128455. ⟨10.1016/j.micres.2026.128455⟩ Article dans une revue hal-05478791v1
The Microbial Anti-Inflammatory Molecule (MAM) is a key protein processed and exported to Faecalibacterium duncaniae envelope Thaís Vilela Rodrigues,Sylvain Marthey,Sandrine Auger,Luis Lima de Jesus,Céline Henryet al. Gut microbes, 2025, 17 (1), pp.2519695. ⟨10.1080/19490976.2025.2519695⟩ Article dans une revue hal-05156716v1
Rôle de la dysbiose du microbiote intestinal dans les maladies métaboliques Sandrine Auger,Jean-Marc Chatel Médecine des Maladies Métaboliques, 2025, 19 (2), pp.161-165. ⟨10.1016/j.mmm.2025.01.003⟩ Article dans une revue hal-05106092v1
Marked reduction of SARS-CoV-2 infection and improved recovery following supplementation with a probiotic mix of four strains and two strains of Bifidobacterium breve in hamsters Edgar Torres-Maravilla,Marine Wasniewski,Aurélie Wauquier,Alexandre Servat,Evelyne Picard-Meyeret al. Applied and Environmental Microbiology, 2025, 91 (6), pp.e0064825. ⟨10.1128/aem.00648-25⟩ Article dans une revue anses-05157590v1
Faecalibacterium Diversity in the Gut Microbiome of Crohn's Disease Patients Paul Mclellan,Sandrine Auger,Marie Therese Goudiaby,Loic Brot,Nicolas Benechet al. United European Gastroenterology Journal, 2025, 13 (8), pp.1480-1490. ⟨10.1002/ueg2.70023⟩ Article dans une revue hal-05106089v1
C-section and systemic inflammation synergize to disrupt the neonatal gut microbiota and brain development in a model of prematurity Cécile Morin,Flora Faure,Julie Mollet,David Guenoun,Ariane Heydari-Olyaet al. Brain, Behavior, and Immunity, 2025, 123, pp.824-837. ⟨10.1016/j.bbi.2024.10.023⟩ Article dans une revue hal-05151481v1
Faecalibacterium duncaniae as a novel next generation probiotic against influenza Loïc Chollet,Séverine Heumel,Lucie Deruyter,Fabrice Bouilloux,Lou Delvalet al. Frontiers in Immunology, 2024, 15, pp.1347676. ⟨10.3389/fimmu.2024.1347676⟩ Article dans une revue hal-04786870v1
Exploring Disease Management and Control through Pathogen Diagnostics and One Health Initiative : A Concise Review Riya Mukherjee,Jasmina Vidic,Sandrine Auger,Hsiao-Chuan Wen,Ramendra Pati Pandeyet al. Antibiotics, 2023, 13 (1), pp.17. ⟨10.3390/antibiotics13010017⟩ Article dans une revue hal-04664074v1
Faecalibacterium : a bacterial genus with promising human health applications Rebeca Martín,David Rios-Covian,Eugénie Huillet,Sandrine Auger,Sarah Khazaalet al. FEMS Microbiology Reviews, 2023, 47 (4), pp. 1-18. ⟨10.1093/femsre/fuad039⟩ Article dans une revue hal-04189185v1
Colorimetric aptasensor for detection of Bacillus cytotoxicus spores in milk and ready-to-use food Francesco Rizzotto,Marco Marin,Christine Péchoux,Sandrine Auger,Jasmina Vidic Heliyon, 2023, 9 (7), pp.e17562. ⟨10.1016/j.heliyon.2023.e17562⟩ Article dans une revue hal-04189190v1
The Tolerance of Gut Commensal Faecalibacterium to Oxidative Stress Is Strain Dependent and Relies on Detoxifying Enzymes Tatiana Botin,Luis Ramirez-Chamorro,Jasmina Vidic,Philippe Langella,Isabelle Martin-Verstraeteet al. Applied and Environmental Microbiology, 2023, 89 (7), pp.e00606-23. ⟨10.1128/aem.00606-23⟩ Article dans une revue hal-04189195v1
Impact of Dietary Arachidonic Acid on Gut Microbiota Composition and Gut–Brain Axis in Male BALB/C Mice Katleen Pinchaud,Zeeshan Hafeez,Sandrine Auger,Jean-Marc Chatel,Sead Chadiet al. Nutrients, 2022, 14 (24), pp.5338. ⟨10.3390/nu14245338⟩ Article dans une revue hal-04083922v1
Gene co-expression network analysis of the human gut commensal bacterium Faecalibacterium prausnitzii in R-Shiny Sandrine Auger,Virginie Mournetas,Hélène Chiapello,Valentin Loux,Philippe Langellaet al. PLoS ONE, 2022, 17 (11), pp. e0271847. ⟨10.1371/journal.pone.0271847⟩ Article dans une revue hal-04083924v1
Description of a Newly Isolated Blautia faecis Strain and Its Benefit in Mouse Models of Post-Influenza Secondary Enteric and Pulmonary Infections Sophie Verstraeten,Valentin Sencio,Audrey Raise,Eugénie Huillet,Séverine Layecet al. Nutrients, 2022, 14 (7), pp.1478. ⟨10.3390/nu14071478⟩ Article dans une revue hal-03649191v1
Intraspecific Diversity of Microbial Anti-Inflammatory Molecule (MAM) from Faecalibacterium prausnitzii Sandrine Auger,Camille Kropp,Esther Borras-Nogues,Wasaporn Chanput,Gwenaelle Andre-Lerouxet al. International Journal of Molecular Sciences, 2022, 23 (3), pp.1705. ⟨10.3390/ijms23031705⟩ Article dans une revue hal-03752257v1
Metal oxide nanoparticles for safe active and intelligent food packaging Maria Vesna Nikolic,Zorka Vasiljevic,Sandrine Auger,Jasmina Vidic Trends in Food Science and Technology, 2021, 116, pp.655-668. ⟨10.1016/j.tifs.2021.08.019⟩ Article dans une revue hal-03798880v1
Bacillus subtilis Regulators MntR and Zur Participate in Redox Cycling, Antibiotic Sensitivity, and Cell Wall Plasticity Paola Randazzo,Jamila J. Anba-Mondoloni,Anne Aubert-Frambourg,Alain Guillot,Christine Péchouxet al. Journal of Bacteriology, 2020, 202 (5), ⟨10.1128/JB.00547-19⟩ Article dans une revue hal-02889085v1
Prophylactic Faecalibacterium prausnitzii treatment prevents the acute breakdown of colonic epithelial barrier in a preclinical model of pelvic radiation disease Alexia Lapiere,Mallia Geiger,Véronique Robert,Christelle Demarquay,Sandrine Augeret al. Gut microbes, 2020, 12 (1), pp.1-15. ⟨10.1080/19490976.2020.1812867⟩ Article dans une revue hal-03194901v1
Synthesis and antibacterial activity of iron manganite (FeMnO 3 ) particles against the environmental bacterium Bacillus subtilis † Zorka Z Vasiljevic,Milena P Dojcinovic,Jugoslav B Krstic,Vesna Ribic,Nenad B Tadicet al. RSC Advances, 2020, 10, ⟨10.1039/d0ra01809k⟩ Article dans une revue hal-02889105v1
Exploring the impact of Mg-doped ZnO nanoparticles on a model soil microorganism Bacillus subtilis Sandrine Auger,Céline Henry,Christine Péchaux,Nathalie Lejal,Valentina Zanetet al. Ecotoxicology and Environmental Safety, 2019, 182, ⟨10.1016/j.ecoenv.2019.109421⟩ Article dans une revue hal-02889082v1
Activity evaluation of pure and doped zinc oxide nanoparticles against bacterial pathogens and saccharomyces cerevisiae V. Zanet,Jasmina Vidic,Sandrine Auger,Priya Vizzini,G. Lippeet al. Journal of Applied Microbiology, 2019, pp.1-12. ⟨10.1111/jam.14407⟩ Article dans une revue hal-02617964v1
Exploring multiple effects of Zn0.15Mg0.85O nanoparticles on Bacillus subtilis and macrophages Sandrine Auger,Céline Henry,Christine Longin,Sneha Suman,Nathalie Lejalet al. Scientific Reports, 2018, 8 (1), ⟨10.1038/s41598-018-30719-9⟩ Article dans une revue hal-01867036v1
Revisiting the in vivo GlnR-binding sites at the genome scale in Bacillus subtilis Paola Randazzo,Anne Aucouturier,Olivier Delumeau,Sandrine Auger BMC Research Notes, 2017, 10 (1), pp.422. ⟨10.1186/s13104-017-2703-9⟩ Article dans une revue hal-05070787v1
Revisiting the in vivo GlnR-binding sites at the genome scale in Bacillus subtilis Paola Randazzo,Anne Aucouturier,Olivier Delumeau,Sandrine Auger BMC Research Notes, 2017, 10 (1), ⟨10.1186/s13104-017-2703-9⟩ Article dans une revue hal-02889071v1
Termination factor Rho: From the control of pervasive transcription to cell fate determination in Bacillus subtilis. Vladimir Bidnenko,Aleksandra Grylak-Mielnicka,Pierre Nicolas,Olivier Delumeau,Sandrine Augeret al. PLoS Genetics, 2017, 13 (7), 47 p. ⟨10.1371/journal.pgen.1006909⟩ Article dans une revue hal-01608054v1
Genetic engineering of the branched fatty acid metabolic pathway of Bacillus subtilis for the overproduction of surfactin C14 isoform Debarun Dhali,François Coutte,Anthony Argüelles Arias,Sandrine Auger,Vladimir V. Bidnenkoet al. Biotechnology Journal, 2017, 12 (7), pp.23. ⟨10.1002/biot.201600574⟩ Article dans une revue hal-01502183v1
The MarR-like protein PchR (YvmB) regulates expression of genes involved in pulcherriminic acid biosynthesis and in the initiation of sporulation in Bacillus subtilis Paola Randazzo,Anne Aubert,Alain Guillot,Sandrine Auger BMC Microbiology, 2016, 16, ⟨10.1186/s12866-016-0807-3⟩ Article dans une revue hal-02637642v1
Genome-wide mapping of TnrA-binding sites provides new insights into the TnrA regulon in &lt;em&gt;Bacillus subtilis&lt;/em&gt; Nicolas N. Mirouze,Elena E. Bidnenko,Philippe P. Noirot,Sandrine Auger MicrobiologyOpen, 2015, 4 (3), pp.423-435. ⟨10.1002/mbo3.249⟩ Article dans une revue hal-02634282v1
Genome-wide identification of [i]Bacillus subtilis[/i] Zur-binding sites associated with a Zur box expands its known regulatory network Eric Prestel,Philippe Noirot,Sandrine Auger BMC Microbiology, 2015, 15, ⟨10.1186/s12866-015-0345-4⟩ Article dans une revue hal-01204456v1
[i]Bacillus cytotoxicus[/i] sp. nov. is a novel thermotolerant species of the [i]Bacillus cereus[/i] Group occasionally associated with food poisoning Marie Helene M. H. Guinebretière,Sandrine Auger,Nathalie N. Galleron,Matthias M. Contzen,Benoit B. de Sarrauet al. International Journal of Systematic and Evolutionary Microbiology, 2013, 63, pp.31-40. ⟨10.1099/ijs.0.030627-0⟩ Article dans une revue hal-01000679v1
Bacillus cytotoxicus sp. nov. is a new thermotolerant species of the Bacillus cereus Group occasionally associated with food poisoning. Marie Helene Guinebretière,Sandrine Auger,Nathalie N. Galleron,Matthias M. Contzen,Benoit B. de Sarrauet al. International Journal of Systematic and Evolutionary Microbiology, 2012 Article dans une revue hal-01329878v1
Complete Genome Sequence of the Highly Hemolytic Strain Bacillus cereus F837/76 Sandrine Auger,Nathalie N. Galleron,Béatrice Segurens,Carole C. Dossat,Alexandre A. Bolotineet al. Journal of Bacteriology, 2012, 194 (6), pp.1630 - 1630. ⟨10.1128/JB.06719-11⟩ Article dans une revue hal-01004271v1
Adaptation of Bacillus cereus, an ubiquitous worldwide-distributed foodborne pathogen, to a changing environment Frederic Carlin,Julien Brillard,Veronique Broussolle,Thierry Clavel,Catherine Duportet al. Food Research International, 2009, 43 (7), pp.1885-1894. ⟨10.1016/j.foodres.2009.10.024⟩ Article dans une revue istex hal-01204240v1
Biofilm formation and cell surface properties among pathogenic and nonpathogenic strains of the Bacillus cereus group. Sandrine Auger,Nalini Ramarao,Christine Faille,Agnès Fouet,Stéphane Aymerichet al. Applied and Environmental Microbiology, 2009, 75 (20), pp.6616-8. ⟨10.1128/aem.00155-09⟩ Article dans une revue pasteur-00512106v1
The genetically remote pathogenic strain NVH391-98 of the Bacillus cereus group is representative of a cluster of thermophilic strains Sandrine Auger,Nathalie Galleron,Elena Bidnenko,S. Dusko Ehrlich,Alla Lapiduset al. Applied and Environmental Microbiology, 2008, 74 (4), pp.1276-1280. ⟨10.1128/AEM.02242-07⟩ Article dans une revue hal-02889116v1
Extending the Bacillus cereus group genomics to putative food-borne pathogens of different toxicity Alla Lapidus,Eugene Goltsman,Sandrine Auger,Nathalie Galleron,Béatrice Ségurenset al. Chemico-Biological Interactions, 2008, 171 (2), pp.236-249. ⟨10.1016/j.cbi.2007.03.003⟩ Article dans une revue istex hal-04314336v1
Autoinducer 2 affects biofilm formation by Bacillus cereus Sandrine Auger,Evelyne Krin,Stephane S. Aymerich,Michel M. Gohar Applied and Environmental Microbiology, 2006, 72 (1), pp.937-941. ⟨10.1128/AEM.72.1.937-941.2006⟩ Article dans une revue hal-02663988v1
Autoinducer 2 affects biofilm formation by Bacillus cereus Sandrine Auger,E. Krin,Stéphane Aymerich,M. Gohar Applied and Environmental Microbiology, 2006, 72, pp.937-941 Article dans une revue hal-00088709v1
Global Control of Cysteine Metabolism by CymR in Bacillus subtilis Sergine Even,Pierre Burguière,Sandrine Auger,Olga Soutourina,Antoine Danchinet al. Journal of Bacteriology, 2006, 188 (6), pp.2184-2197. ⟨10.1128/JB.188.6.2184-2197.2006⟩ Article dans une revue hal-03292252v1
The PatB protein of Bacillus subtilis is a C-S-lyase Sandrine Auger,M.P. Gomez,A. Danchin,I. Martin-Verstraete Biochimie, 2005, 87 (2), pp.231-238. ⟨10.1016/j.biochi.2004.09.007⟩ Article dans une revue istex hal-02680864v1
Regulation of the Bacillus subtilis ytmI operon, involved in sulfur metabolism Pierre Burguière,Juliette Fert,Isabelle Guillouard,Sandrine Auger,Antoine Danchinet al. Journal of Bacteriology, 2005, 87 (17), pp.6019-6030. ⟨10.1128/JB.187.17.6019-6030.2005⟩ Article dans une revue hal-02681047v1
Three different systems participate in l-Cystine uptake in Bacillus subtilis Pierre Burguière,Sandrine Auger,Marie-Françoise Hullo,Antoine Danchin,Isabelle Martin-Verstraete Journal of Bacteriology, 2004, 186 (15), pp.4875-4884. ⟨10.1128/JB.186.15.4875-4884.2004⟩ Article dans une revue hal-02889124v1
The metNPQ operon of Bacillus subtilis encodes an ABC permease transporting methionine sulfoxide, D-and L-methionine. Marie-Françoise Hullo,Sandrine Auger,Elie Dassa,Antoine Danchin,Isabelle Martin-Verstraete Research in Microbiology, 2004, 155 (2), pp.80-86. ⟨10.1016/j.resmic.2003.11.008⟩ Article dans une revue istex hal-00020363v1
Conversion of methionine to cysteine in Bacillus subtilis and its regulation Marie-Françoise Hullo,Sandrine Auger,Olga Soutourina,Octavian Barzu,Mireille Yvonet al. Journal of Bacteriology, 2004, 189 (1), pp 187-197. ⟨10.1128/JB.01273-06⟩ Article dans une revue hal-04190311v1
Identification of Bacillus subtilis CysL, a regulator of the cysJI Operon, which encodes sulfite reductase Isabelle Guillouard,Sandrine Auger,Marie-Françoise Hullo,Farid Chetouani,Antoine Danchinet al. Journal of Bacteriology, 2002, 184 (17), pp.4681-4689. ⟨10.1128/jb.184.17.4681-4689.2002⟩ Article dans une revue hal-02889129v1
The metIC operon involved in methionine biosynthesis in Bacillus subtilis is controlled by transcription antitermination Sandrine Auger,W. Yuen,Antoine Danchin,Isabelle Martin-Verstraete Microbiology, 2002, 148 (2), pp.507-518. ⟨10.1099/00221287-148-2-507⟩ Article dans une revue hal-02889132v1
Global Expression Profile of Bacillus subtilis Grown in the Presence of Sulfate or Methionine Sandrine Auger,Antoine Danchin,Isabelle Martin-Verstraete Journal of Bacteriology, 2002, 184 (18), pp.5179-5186. ⟨10.1128/jb.184.18.5179-5186.2002⟩ Article dans une revue hal-02889134v1
Sulfur-limitation-regulated proteins in Bacillus subtilis: a two-dimensional gel electrophoresis study Jean-Yves Coppée,Sandrine Auger,Evelyne Turlin,Agnieszka Sekowska,Jean-Pierre Le Caeret al. Microbiology, 2001, 147 (6), pp.1631-1640. ⟨10.1099/00221287-147-6-1631⟩ Article dans une revue hal-02889151v1

Communication dans un congrès (4)

Potential use of Faecalibacterium prausnitzii in human health Sandrine Auger Probiota 2024, NutraIngredients, Feb 2024, Milan, Italy Communication dans un congrès hal-04466369v1
Faecalibacterium duncaniae A2-165 regulates the expression of butyrate synthesis, ferrous iron uptake, and stress-response genes based on acetate consumption Sophie Verstraeten,Séverine Layec,Sandrine Auger,Catherine Juste,Céline Henryet al. Colloque du Club des bactéries Lactiques (CBL), Jun 2024, Dijon, France Communication dans un congrès hal-04734183v1
Towards the diversity and characterization of MAM (Microbial Anti-inflammatory Molecule), from Faecalibacterium Thaís Vilela,Vasco Ariston de Carvalho Azevedo,Céline Henry,Sandrine Auger,Sylvain Martheyet al. 68th Brazilian Congress of Genetics, Sep 2023, Ouro Preto – MG, Brazil Communication dans un congrès hal-04329983v1
Intraspecific diversity of Microbial Anti-inflammatory Molecule (MAM) from Faecalibacterium prausnitzii Sandrine Auger BactInflam Webinar, Jun 2022, Jouy-en-Josas, France Communication dans un congrès hal-04328397v1

Poster de conférence (2)

Colorimetric aptasensor for the detection of Bacillus cytotoxicus spores in milk and ready-to-use food Sandrine Auger,Francesco Rizzotto,Jasmina Vidic 7th International ISEKI-food conference, Jul 2023, Palaiseau, France Poster de conférence hal-04329160v1
Additive deleterious effects of delivery mode on perinatal brain injuries: microbiota's fault Sandrine Auger,Cecile Morin,Cindy Bokobza 16th European Meeting on Glial Cells in Health and Disease, Jul 2023, Berlin, Germany Poster de conférence hal-04328435v1

Pré-publication, Document de travail (1)

NeighborFinder: an R package inferring local microbial network around a species of interest Mathilde Sola,Adrien Paravel,Sandrine Auger,Jean-Marc Chatel,Florian Plaza-Oñateet al. 2026 Pré-publication, Document de travail hal-05408767v2

HDR (1)

Study of biological networks involved in the adaptation of Bacillus subtilis and Faecalibacterium to their environment Sandrine Auger Life Sciences [q-bio]. Université Paris-Saclay, 2023 HDR tel-04190291v1

Mémoire d'étudiant (2)

Étude de la croissance de Faecalibacterium duncaniae en présence de protéines d'origine végétale et sélection de variants aérotolérants. Sandrine Auger,Rime Chebbo Sciences du Vivant [q-bio]. 2024 Mémoire d'étudiant hal-04664026v1
Etude du stress oxydant chez Faecalibacterium prausnitzii Sandrine Auger,Tatiana Botin Sciences du Vivant [q-bio]. 2002 Mémoire d'étudiant hal-04328411v1