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Sandrine CHARLES
Professeur des Universités
4
Documents
Affiliations actuelles
- 194495
- 10025
- 543541
Identifiants chercheurs
- sandrine-charles
- 0000-0003-4604-0166
- Google Scholar : https://scholar.google.com/citations?user=QiapAvIAAAAJ&hl=en
- IdRef : 09293692X
Présentation
My research activities focus on quantitative risk assessment in ecotoxicology. This involves developing methods and tools to identify potentially harmful substances, defining acceptable concentration thresholds at different levels of biological organization, creating environmental quality indicators, and characterizing the causal links between toxicity and ecological impact. To tackle the issue of environmental protection, two research lines are being conducted simultaneously. Firstly, a priori risk assessment is being carried out to comprehend how contaminants affect individual life-history traits such as survival, growth, and reproduction. This information is then extrapolated to population and community levels. Secondly, a posteriori diagnosis is being conducted to evaluate the quality of natural environments and their effects on indigenous populations. Employing an interdisciplinary and integrated approach, along with the development of mathematical and statistical models for predictive purposes, the aim is to answer the key question of the change of scale. This refers to the link between the scale of observation of effects and that of the levels of biological organisation to be protected, such as the individual, population, community, and ecosystem.
Methods and tools used to achieve this are: mechanistic effect modelling, dynamical systems, population dynamics models, Bayesian inference, and sensitivity analyses.
Domaines de recherche
Ecotoxicologie
Ecosystèmes
Environnement et Société
Statistiques [math.ST]
Modélisation et simulation
Compétences
Publications
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Development and validation of an OECD reproductive toxicity test guideline with the pond snail Lymnaea stagnalis (Mollusca, Gastropoda)Regulatory Toxicology and Pharmacology, 2014, 70 (3), pp.605-614. ⟨10.1016/j.yrtph.2014.09.004⟩
Article dans une revue
hal-01210250v1
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Survival data analyses in ecotoxicology: critical effect concentrations, methods and models. What should we use?Ecotoxicology, 2012, 21, pp.1072--1083. ⟨10.1007/s10646-012-0860-0⟩
Article dans une revue
hal-02297003v1
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Comparison of bioassays with different exposure time patterns: The added value of dynamic modelling in predictive ecotoxicologyEcotoxicology and Environmental Safety, 2012, 75, pp.80-86. ⟨10.1016/j.ecoenv.2011.08.006⟩
Article dans une revue
halsde-00685679v1
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A New Perspective on the Dunnett Procedure: Filling the Gap Between Noec/Loec and Ecx ConceptsEnvironmental Toxicology and Chemistry, 2011, 30, pp.2888-2891. ⟨10.1002/etc.686⟩
Article dans une revue
hal-02299273v1
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