Sandrine Cojean Maître de Conférences à Université Paris-Saclay (Orsay)Ingénieure en Recherche Hospitalière à CNR Paludisme (Hôpital Bichat Claude Bernard, Paris)

Publications

Article dans une revue (22)

Are hydrophilic deep eutectic solvents a potential vehicle for topical delivery of Amphotericin B against cutaneous leishmaniasis? An investigation of physicochemical properties, tolerability and antileishmanial efficacy Cảnh Hưng Nguyễn,Catherine Cailleau,Natalie Fournier,Luc Augis,Françoise Mercier-Noméet al. International Journal of Pharmaceutics, 2026, 689, pp.126439. ⟨10.1016/j.ijpharm.2025.126439⟩ Article dans une revue hal-05397306v1
Re-sensitization of antimony-resistant Leishmania by highly potent SbV-porphyrin through the involvement of ERG6-coding gene Ellen Gonçalves De Oliveira,Juliane Sousa Lanza,Sandrine Cojean,Paulo Otávio L. Moreira,Luiza Guimarães Tuneset al. Biomedicine and Pharmacotherapy, 2025, 187, pp.118059. ⟨10.1016/j.biopha.2025.118059⟩ Article dans une revue hal-05445980v1
Resistance to Antileishmanial Drug Candidates: A Flowchart for an Early Phenotypic Evaluation of Risk Nalia Mekarnia,Sandrine Cojean,Philippe Loiseau Drugs and Drug Candidates, 2025, 4 (3), pp.38. ⟨10.3390/ddc4030038⟩ Article dans une revue hal-05235475v1
Pharmacophore-guided optimization of the hit compound CTN1122 in the design of promising imidazo[1,2- a ]pyrazine derivatives targeting the casein kinase 1 for antileishmanial therapy Lhana Tisseur,Cédric Logé,Sandrine Cojean,Khadidiatou Gassama,Lilian Karcheret al. RSC Medicinal Chemistry, 2025, 16, pp.3746-3763. ⟨10.1039/d5md00257e⟩ Article dans une revue hal-05173262v1
Chemical analysis by molecular networking methods on extracts of Saba senegalensis (A.DC.) Pichon (Apocynaceae) and its anthelmintic activity on Caenorhabditis elegans Mohamed Belemlilga,Hazrina Hazni,Aristide Traore,Indira Dennemont,Sébastien Pomelet al. Clinical Traditional Medicine and Pharmacology, 2025, 6 (1), pp.200195. ⟨10.1016/j.ctmp.2025.200195⟩ Article dans une revue hal-05149228v1
Assessment of ex vivo antimalarial drug efficacy in African Plasmodium falciparum parasite isolates, 2016–2023: a genotype–phenotype association study Jason Rosado,Abebe Fola,Sandrine Cojean,Véronique Sarrasin,Romain Coppéeet al. EBioMedicine, 2025, 118 (1), pp.105835. ⟨10.1016/j.ebiom.2025.105835⟩ Article dans une revue hal-05169453v2
Investigating the C2 Modulation of the Imidazo[1,2‐ a ]pyrazine‐Based Hit Compound CTN1122: Synthesis, in vitro Antileishmanial Activity, Cytotoxicity and Casein Kinase 1 Inhibition Lhana Tisseur,Sandrine Cojean,Khadidiatou Gassama,Cédric Logé,Fabrice Pagniezet al. ChemMedChem, 2025, 20 (6), pp.e202400862. ⟨10.1002/cmdc.202400862⟩ Article dans une revue hal-05181232v1
Synthesis and in vitro/in silico evaluation of the antimalarial activity of potential amino-quinoline derivatives Moussa Touré,Abdoulaye Gassama,Oumar Sambou,Christian Cavé,Sandrine Cojean European Journal of Medicinal Chemistry Reports, 2025, 13, pp.100241. ⟨10.1016/j.ejmcr.2024.100241⟩ Article dans une revue hal-05445961v1
Biological properties and in silico studies of thiazolopyrimidine derivatives active against visceral and cutaneous Leishmania spp. amastigote forms Gulsah Bayraktar,Pascal Marchand,Euzébio Guimarães Barbosa,Marilia Cecilia da Silva,Karen Cacilda Weberet al. European Journal of Medicinal Chemistry Reports, 2024, 12, pp.100228. ⟨10.1016/j.ejmcr.2024.100228⟩ Article dans une revue hal-05088062v1
The Synthesis of 2′-Hydroxychalcones under Ball Mill Conditions and Their Biological Activities Imen Abid,Wassim Moslah,Sandrine Cojean,Nicolas Imbert,Philippe M Loiseauet al. Molecules, 2024, 29 (8), pp.1819. ⟨10.3390/molecules29081819⟩ Article dans une revue hal-04550832v1
Chemoselective Synthesis and Anti-Kinetoplastidal Properties of 2,6-Diaryl-4H-tetrahydro-thiopyran-4-one S-Oxides: Their Interplay in a Cascade of Redox Reactions from Diarylideneacetones Thibault Gendron,Don Antoine Lanfranchi,Nicole I Wenzel,Hripsimée Kessedjian,Beate Jannacket al. Molecules, 2024, 29 (7), pp.1620. ⟨10.3390/molecules29071620⟩ Article dans une revue hal-04583951v1
Effect of Phlebotomus papatasi on the fitness, infectivity and antimony-resistance phenotype of antimony-resistant Leishmania major Mon-25 Nalia Mekarnia,Kamal-Eddine Benallal,Jovana Sádlová,Barbora Vojtková,Aurélie Mauraset al. International journal for parasitology. Drugs and drug resistance, 2024, 25, pp.100554. ⟨10.1016/j.ijpddr.2024.100554⟩ Article dans une revue hal-04632483v1
Synthesis and Antileishmanial Activity of 1,2,4,5-Tetraoxanes against Leishmania donovani Lília Cabral,Sébastien Pomel,Sandrine Cojean,Patrícia Amado,Philippe Loiseauet al. Molecules, 2020, 25 (3), pp.465. ⟨10.3390/molecules25030465⟩ Article dans une revue hal-05149167v1
Antiprotozoal activity of medicinal plants used by Iquitos-Nauta road communities in Loreto (Peru) Pedro Vásquez-Ocmín,Sandrine Cojean,Elsa Rengifo,Soulaf Suyyagh-Albouz,Carlos Amasifuen Guerraet al. Journal of Ethnopharmacology, 2018, 210, pp.372-385. ⟨10.1016/j.jep.2017.08.039⟩ Article dans une revue istex hal-05149102v1
New Water-Soluble Polymeric Prodrugs of 2-n-propylquinoline: Synthesis and Evaluation of In Vitro and In Vivo Activities Against Leishmania donovani Vasanthan Ravichandran,Nalia Mekarnia,Sébastien Pomel,Sandrine Cojean,Laurent Ferriéet al. Regenerative Engineering and Translational Medicine, 2018, 4 (1), pp.11-20. ⟨10.1007/s40883-018-0045-3⟩ Article dans une revue hal-05149115v1
Antiplasmodial Securinega alkaloids from Phyllanthus fraternus: Discovery of natural (+)-allonorsecurinine Gustav Komlaga,Grégory Genta-Jouve,Sandrine Cojean,Rita Dickson,Merlin L.K. Mensahet al. Tetrahedron Letters, 2017, 58 (38), pp.3754-3756. ⟨10.1016/j.tetlet.2017.08.045⟩ Article dans une revue istex hal-05521917v1
Antiplasmodial activity of selected medicinal plants used to treat malaria in Ghana Gustav Komlaga,Sandrine Cojean,Rita Dickson,Mehdi Beniddir,Soulaf Suyyagh-Albouzet al. Parasitology Research, 2016, 115 (8), pp.3185-3195. ⟨10.1007/s00436-016-5080-8⟩ Article dans une revue hal-05521857v1
Targeting sterol metabolism for the development of antileishmanials Sébastien Pomel,Sandrine Cojean,Philippe Loiseau Trends in Parasitology, 2015, 31 (1), pp.5-7. ⟨10.1016/j.pt.2014.11.007⟩ Article dans une revue istex hal-05148982v1
In vitro and in vivo antileishmanial properties of a 2-n-propylquinoline hydroxypropyl β-cyclodextrin formulation and pharmacokinetics via intravenous route Kaluvu Balaraman,Nashira Campos Vieira,Fathi Moussa,Joël Vacus,Sandrine Cojeanet al. Biomedicine and Pharmacotherapy, 2015, 76, pp.127-133. ⟨10.1016/j.biopha.2015.10.028⟩ Article dans une revue istex hal-05149031v1
The Antimalarial Potential of Three Ghanaian Medicinal Plants Gustav Komlaga,Sandrine Cojean,Mehdi A Beniddir Herbal Medicine: Open Access, 2015, 1 (1), ⟨10.21767/2472-0151.10004⟩ Article dans une revue hal-05521840v1
VFV as a New Effective CYP51 Structure-Derived Drug Candidate for Chagas Disease and Visceral Leishmaniasis Galina Lepesheva,Tatiana Hargrove,Girish Rachakonda,Zdzislaw Wawrzak,Sébastien Pomelet al. Journal of Infectious Diseases, 2015, 212 (9), pp.1439-1448. ⟨10.1093/infdis/jiv228⟩ Article dans une revue hal-05149012v1
Synthesis and antiprotozoal activity of original porphyrin precursors and derivatives Zahra Abada,Sandrine Cojean,Sébastien Pomel,Laurent Ferrié,Bernardin Akagahet al. European Journal of Medicinal Chemistry, 2013, 67 (2), pp.158-165. ⟨10.1016/j.ejmech.2013.06.002⟩ Article dans une revue hal-05148876v1

Poster de conférence (1)

In silico and in vitro assessments of thio-linked pyrimidine-based compounds against Leishmania donovani Ines Carreira Costa,Margarida M Alves,Rita C. Guedes,José A. Paixão,Philippe M Loiseauet al. Congrès SFP SFMM, Jun 2025, Amiens, France Poster de conférence hal-05173348v1

Communication dans un congrès (4)

In silico and in vitro assessments of thio-linked pyrimidine-based compounds against Leishmania donovani Ines Carreira Costa,Margarida Gonçalves,José A. Paixão,Philippe M Loiseau,Sandrine Cojeanet al. Journée de l'école doctorale, École doctorale du médicament du fondamental à l'appliqué, Jun 2025, Orsay, France Communication dans un congrès hal-05173445v1
In silico and in vitro assessments of thio-linked pyrimidine-based compounds against Leishmania donovani Inês Costa,Margarida M. Alves,Rita C. Guedes,José A. Paixão,Philippe M Loiseauet al. CAPF, May 2025, Lille, France Communication dans un congrès hal-05173401v1
Modifying positions 2 or 8 of the imidazo[1,2-a]pyrazine lead compound CTN1122 affects its antileishmanial activity, L-CK1.2 kinase inhibition, and safety profile Lhana Tisseur,Marc-Antoine Bazin,Sandrine Cojean,Fabrice Pagniez,Cédric Logéet al. GP2A 2024, Aug 2024, Coimbra, Portugal Communication dans un congrès hal-04708945v1
Synthesis of flavonoid derivatives precursors of active pharmaceutical ingredients by mechanochemistry Imen Abid,Wassim Moslah,Sandrine Cojean,Nicolas Imbert,P.M. Loiseauet al. GreenChem-24 : 6th International conference on green chemistry and sustainable engineering, Jul 2024, Lisbonne, Portugal Communication dans un congrès hal-04883885v1