Sébastien ARTHAUD Ingénieur de Recherche à l'Université Claude Bernard Lyon1

Publications

Poster de conférence (10)

LIFESPAN SLEEP ALTERATION IN MICE MODELLING THE HUMAN NEUROMELANIN ACCUMULATION IN CATECHOLAMINERGIC NEURONS Sébastien Arthaud,Jean-Christophe Comte,Jiong Liu,Núria Peñuelas,Anna Lagunaset al. Neurofrance 2025, May 2025, Montpellier, France. 2025 Poster de conférence hal-05119338v1
Nouveau modèle expérimental de trouble du comportement en sommeil paradoxal (TCSP) chez la souris sauvage Blandine Duval,Sebastien Arthaud,Justin Malcey,Amarine Chancel,Pierre-Hervé Luppiet al. Le congrès du Sommeil 2024, Nov 2024, Lille, France. 22 (1), pp.85, 2025, ⟨10.1016/j.msom.2025.01.137⟩ Poster de conférence hal-05119375v1
DEVELOPMENT OF A PRECLINICAL MODEL OF REM SLEEP BEHAVIOR DISORDER (RBD), A PRODROMAL PARASOMNIA OF PARKINSON’S DISEASE, IN M83 TRANSGENIC MICE Sébastien Arthaud,Maxime Grenot,Latifa Lakhdar,Thierry Baron,Patrice Fort Neurofrance 2023, May 2023, LYON, France Poster de conférence hal-04178071v1
EVOLUTION WITH AGING OF SLEEP MICROARCHITECTURE IN MICE ACCUMULATING NEUROMELANIN IN CATECHOLAMINERGIC NEURONS, A NEW HUMANIZED PARKINSON’S DISEASE MODEL Patrice Fort,Romain Bouet,Maxime Grenot,Jiong Liu,Nuria Peñuelaset al. NeuroFrance 2023, May 2023, Lyon, France Poster de conférence hal-04178056v1
Evolution of the sleep-waking cycle in transgenic mice with an age-dependent accumulation of neuromelanin in catecholaminergic neurons, a new humanized model of Parkinson’s Disease Sébastien Arthaud,Jiong Liu,Nuria Peñuelas,Ariadana Laguna,Miquel Vilaet al. FENS Forum, Jul 2022, PARIS, France Poster de conférence hal-04176874v1
Modulation of hypothalamic MCH-expressing neurons by pharmacogenetic tools strongly alters the sleep-waking cycle in mice Christophe Varin,Sébastien Arthaud,Yohan Cherasse,Michael Lazarus,Thierry Gallopinet al. 22nd Congress of the European-Sleep-Research-Society, Sep 2014, Tallinn, Estonia. Journal of sleep Research, 23 (P808), pp.254, 2014 Poster de conférence hal-02345870v1
Efficient paradoxical (REM) sleep homeostatic regulation in mice: reports on sleep architecture and neuronal activation Sébastien Arthaud,Christophe Varin,Paul-Antoine Libourel,Patrice Fort,Pierre-Hervé Luppiet al. 22nd Congress of the European-Sleep-Research-Society, Sep 2014, Tallinn, Estonia. Journal of leep Research, 23 (P854), pp.270-71, 2014 Poster de conférence hal-02345904v1
Selective paradoxical sleep deprivation in mice using a new unsupervised automatic method Sébastien Arthaud,Paul-Antoine Libourel,Patrice Fort,Damien Gervasoni,Pierre-Hervé Luppi 21st Congress of the European-Sleep-Research-Society, Sep 2012, Paris, France. 21, pp.326, 2012 Poster de conférence hal-02369336v1
Unsupervised paradoxical sleep deprivation using real-time sleep scoring in rats: a new alternative to the 'flower pot' technique Paul-Antoine Libourel,Sonia Jego,Patrice Fort,Frédéric Brischoux,Jérémy Nigriet al. 21st Congress of the European-Sleep-Research-Society, Sep 2012, Paris, France. 21, pp.326-327, 2012 Poster de conférence hal-02347128v1
Evidence that the lateral hypothalamic area controls paradoxical (REM) sleep by means of descending projections to brainstem GABAergic neurons Clément Olivier,Emilie Sapin,Paul-Antoine Libourel,Sébastien Arthaud,Patrice Fortet al. 21st Congress of the European-Sleep-Research-Society, Sep 2012, Paris, France. Journal of Sleep Research, 21, pp.193, 2012 Poster de conférence hal-02347007v1

Article dans une revue (34)

Bridging the gap between lab and field sleep studies: a proof-of-concept for studying wild rats in semi-captive environments Paul-Antoine Libourel,Sébastien Arthaud,Antoine Bergel,Fabrice Brescia,Azzedine Dibet al. SLEEP Advances, 2025, 6 (2), zpaf036 [12 p.]. ⟨10.1093/sleepadvances/zpaf036⟩ Article dans une revue hal-05519164v1
Probability estimation of narcolepsy type 1 in DTA mice using unlabeled EEG and EMG data Laura Rose,Alexander Neergaard Zahid,Louise Piilgaard,Christine Egebjerg,Frederikke Lynge Sørensenet al. SLEEP Advances, 2025, 6 (2), zpaf025. ⟨10.1093/sleepadvances/zpaf025⟩ Article dans une revue hal-05120846v1
Sleep-dependent infraslow rhythms are evolutionarily conserved across reptiles and mammals Antoine Bergel,Julien Schmidt,Baptiste Barrillot,Sébastien Arthaud,Laetitia Avertyet al. Nature Neuroscience, 2025, ⟨10.1038/s41593-025-02159-y⟩ Article dans une revue hal-05495102v1
Early-onset sleep alterations found in patients with amyotrophic lateral sclerosis are ameliorated by orexin antagonist in mouse models Simon J Guillot,Christina Lang,Marie Simonot,Daniel Beckett,Dorothée Luléet al. Science Translational Medicine, 2025, 17 (783), pp.eadm7580. ⟨10.1126/scitranslmed.adm7580⟩ Article dans une revue inserm-05509033v1
Modelling human neuronal catecholaminergic pigmentation in rodents recapitulates age-related neurodegenerative deficits Ariadna Laguna,Núria Peñuelas,Marta Gonzalez-Sepulveda,Alba Nicolau,Sébastien Arthaudet al. Nature Communications, 2024, 15 (1), pp.8819. ⟨10.1038/s41467-024-53168-7⟩ Article dans une revue hal-04767989v1
Major alteration of motor control during rapid eye movements sleep in mice models of sleep disorders Maxime Grenot,Alexis Roman,Manon Villalba,Anne-Laure Morel,Patrice Fortet al. Sleep, 2024, ⟨10.1093/sleep/zsae178⟩ Article dans une revue hal-04768098v1
Two polygenic mouse models of major depressive disorders identify TMEM161B as a potential biomarker of disease in humans Malika El Yacoubi,Claire Altersitz,Violaine Latapie,Elari Rizkallah,Sébastien Arthaudet al. Neuropsychopharmacology, 2024, 49, pp.1129-1139. ⟨10.1038/s41386-024-01811-8⟩ Article dans une revue inserm-04444848v1
Influenza vaccination induces autoimmunity against orexinergic neurons in a mouse model for narcolepsy Raphaël Bernard-Valnet,David Frieser,Xuan-Hung Nguyen,Leila Khajavi,Clémence Quériaultet al. Brain - A Journal of Neurology , 2022, 145 (6), pp.2018-2030. ⟨10.1093/brain/awab455⟩ Article dans une revue hal-03669984v1
Effects of sex and estrous cycle on sleep and cataplexy in narcoleptic mice Sébastien Arthaud,Manon Villalba,Camille Blondet,Anne-Laure Morel,Christelle Peyron Sleep, 2022, 45 (7), ⟨10.1093/sleep/zsac089⟩ Article dans une revue hal-03748304v1
Granule cells in the infrapyramidal blade of the dentate gyrus are activated during paradoxical (REM) sleep hypersomnia but not during wakefulness: a study using TRAP mice Risa Yamazaki,Dianru Wang,Anna de Laet,Renato Maciel,Claudio Agnorelliet al. Sleep, 2021, 44 (12), pp.zsab173. ⟨10.1093/sleep/zsab173⟩ Article dans une revue hal-03400920v1
Is REM sleep a paradoxical state?: Different neurons are activated in the cingulate cortices and the claustrum during wakefulness and paradoxical sleep hypersomnia Renato Maciel,Risa Yamazaki,Dianru Wang,Anna de Laet,Sébastien Cabreraet al. Biochemical Pharmacology, 2021, 191, pp.114514. ⟨10.1016/j.bcp.2021.114514⟩ Article dans une revue hal-03285342v1
Targeted recombination in active populations as a new mice genetic model to study sleep‐active neuronal populations: Demonstration that Lhx6+ neurons in the ventral zona incerta are activated during paradoxical sleep hypersomnia Hyun‐sook Lee,Risa Yamazaki,Dianru Wang,Sébastien Arthaud,Patrice Fortet al. Journal of Sleep Research, 2020, ⟨10.1111/jsr.12976⟩ Article dans une revue hal-02996227v1
Insights into paradoxical (REM) sleep homeostatic regulation in mice using an innovative automated sleep deprivation method Sébastien Arthaud,Paul-Antoine Libourel,Pierre-Hervé Luppi,Christelle Peyron Sleep, 2020, 43 (7), ⟨10.1093/sleep/zsaa003⟩ Article dans une revue hal-03104247v1
Defining and measuring paradoxical (REM) sleep in animal models of sleep disorders Christelle Peyron,Sébastien Arthaud,Manon Villalba,Patrice Fort Current Opinion in Physiology, 2020, 15, pp.203-209. ⟨10.1016/j.cophys.2020.03.008⟩ Article dans une revue hal-02996296v1
Partial homologies between sleep states in lizards, mammals, and birds suggest a complex evolution of sleep states in amniotes Paul-Antoine Libourel,Baptiste Barrillot,Sébastien Arthaud,Bertrand Massot,Anne-Laure Morelet al. PLoS Biology, 2018, 16 (10), pp.e2005982. ⟨10.1371/journal.pbio.2005982⟩ Article dans une revue hal-02105758v1
ONEIROS, a new miniature standalone device for recording sleep electrophysiology, physiology, temperatures and behavior in the lab and field Bertrand Massot,Sébastien Arthaud,Baptiste Barrillot,Johanna Roux,Gianina Ungureanet al. Journal of Neuroscience Methods, 2018, ⟨10.1016/j.jneumeth.2018.08.030⟩ Article dans une revue hal-01890562v1
INTRAMUSCULAR ADMINISTRATION OF KETAMINE-MEDETOMIDINE ASSURES STABLE ANAESTHESIA NEEDED FOR LONG-TERM SURGERY IN THE ARGENTINE TEGU SALVATOR MERIANAE Baptiste Barrillot,Johanna Roux,Sébastien Arthaud,Laëtitia Averty,Angeline Clairet al. Journal of Zoo and Wildlife Medicine, 2018, 49 (2), pp.291-296. ⟨10.1638/2017-0089.1⟩ Article dans une revue hal-02105781v1
Ventromedial medulla inhibitory neuron inactivation induces REM sleep without atonia and REM sleep behavior disorder Sara Valencia Garcia,Frédéric Brischoux,Olivier Clément,Paul-Antoine Libourel,Sébastien Arthaudet al. Nature Communications, 2018, 9 (1), ⟨10.1038/s41467-017-02761-0⟩ Article dans une revue hal-02104823v1
The inappropriate occurrence of rapid eye movement sleep in narcolepsy is not due to a defect in homeostatic regulation of rapid eye movement sleep Alexis Roman,Soraya Meftah,Sébastien Arthaud,Pierre-Hervé Luppi,C. Peyron Sleep, 2018, 41 (6), pp.zsy046. ⟨10.1093/sleep/zsy046⟩ Article dans une revue hal-02368936v1
CD8 T cell-mediated killing of orexinergic neurons induces a narcolepsy-like phenotype in mice Raphaël Bernard-Valnet,Lidia Yshii,Clémence Quériault,Xuan-Hung Nguyen,Sébastien Arthaudet al. Proceedings of the National Academy of Sciences of the United States of America, 2016, 113 (39), pp.10956 - 10961. ⟨10.1073/pnas.1603325113⟩ Article dans une revue hal-01824562v1
REM Sleep-Dependent Bidirectional Regulation of Hippocampal-Based Emotional Memory and LTP Pascal Ravassard,Al Mahdy Hamieh,Mickaël Antoine Joseph,Nicolas Fraize,Paul-Antoine Libourelet al. Cerebral Cortex, 2016, 26 (4), pp.1488-1500. ⟨10.1093/cercor/bhu310⟩ Article dans une revue hal-04773763v1
REM Sleep-Dependent Bidirectional Regulation of Hippocampal-Based Emotional Memory and LTP Pascal Ravassard,Al Mahdy Hamieh,Mickaël Antoine Joseph,Nicolas Fraize,Paul-Antoine Libourelet al. Cerebral Cortex, 2016, 26 (4), pp.1488-1500. ⟨10.1093/cercor/bhu310⟩ Article dans une revue hal-03398976v1
Sleep architecture and homeostasis in mice with partial ablation of melanin-concentrating hormone neurons Christophe Varin,Sébastien Arthaud,Denise Salvert,Nadine Gay,Paul-Antoine Libourelet al. Behavioural Brain Research, 2016, 298, pp.100-110. ⟨10.1016/j.bbr.2015.10.051⟩ Article dans une revue hal-02336931v1
Paradoxical (REM) sleep deprivation in mice using the small-platforms-over-water method: polysomnographic analyses and melanin-concentrating hormone and hypocretin/orexin neuronal activation before, during and after deprivation Sébastien Arthaud,Christophe Varin,Nadine Gay,Paul-Antoine Libourel,Frédéric Chauveauet al. Journal of Sleep Research, 2015, 24 (3), pp.309-319. ⟨10.1111/jsr.12269⟩ Article dans une revue hal-02336938v1
Glucose Induces Slow-Wave Sleep by Exciting the Sleep-Promoting Neurons in the Ventrolateral Preoptic Nucleus: A New Link between Sleep and Metabolism Christophe Varin,Armelle Rancillac,Hélène Geoffroy,Sébastien Arthaud,Patrice Fortet al. Journal of Neuroscience, 2015, 35 (27), pp.9900-9911. ⟨10.1523/JNEUROSCI.0609-15.2015⟩ Article dans une revue inserm-02121070v1
Biochemical Characterization of a Caspase-3 Far-red Fluorescent Probe for Non-invasive Optical Imaging of Neuronal Apoptosis Valérie Jolivel,Sébastien Arthaud,Béatrice Botia,Christophe Portal,Bruno Delestet al. Journal of Molecular Neuroscience, 2014, 54 (3), pp.451-462. ⟨10.1007/s12031-014-0325-4⟩ Article dans une revue hal-01196843v1
Concordant localization of functional urotensin II and urotensin II-related peptide binding sites in the rat brain: Atypical occurrence close to the fourth ventricle Christine Bucharles,Patrice Bizet,Sébastien Arthaud,Arnaud Arabo,Jérôme Leprinceet al. Journal of Comparative Neurology, 2014, 522 (11), pp.2634-2649. ⟨10.1002/cne.23553⟩ Article dans une revue istex hal-01958600v1
The Inhibition of the Dorsal Paragigantocellular Reticular Nucleus Induces Waking and the Activation of All Adrenergic and Noradrenergic Neurons: A Combined Pharmacological and Functional Neuroanatomical Study Olivier Clément,Sara Valencia Garcia,Paul-Antoine Libourel,Sébastien Arthaud,Patrice Fortet al. PLoS ONE, 2014, 9 (5), pp.e96851. ⟨10.1371/journal.pone.0096851⟩ Article dans une revue hal-02337032v1
Gliotransmission and Brain Glucose Sensing: Critical Role of Endozepines Damien Lanfray,Sébastien Arthaud,Johanne Ouellet,Vincent Compère,Jean-Luc Do Regoet al. Diabetes, 2013, 62 (3), pp.801-810. ⟨10.2337/db11-0785⟩ Article dans une revue hal-01962799v1
Gliotransmission and Brain Glucose Sensing: Critical Role of Endozepines Damien Lanfray,Sébastien Arthaud,Johanne Ouellet,Vincent Compère,Jean-Luc Do Regoet al. Diabetes, 2013, 62 (3), pp.801 - 810. ⟨10.2337/db11-0785⟩ Article dans une revue hal-01939215v1
The Lateral Hypothalamic Area Controls Paradoxical (REM) Sleep by Means of Descending Projections to Brainstem GABAergic Neurons Olivier Clément,Emilie Sapin,Paul-Antoine Libourel,Sébastien Arthaud,Frédéric Brischouxet al. Journal of Neuroscience, 2012, 32 (47), pp.16763-16774. ⟨10.1523/JNEUROSCI.1885-12.2012⟩ Article dans une revue hal-02339533v1
The PACAP-regulated gene selenoprotein T is highly induced in nervous, endocrine, and metabolic tissues during ontogenetic and regenerative processes. Yannick Tanguy,Anthony Falluel-Morel,Sébastien Arthaud,Loubna Boukhzar,Destiny-Love Maneckaet al. Endocrinology, 2011, 152 (11), pp.4322-35. ⟨10.1210/en.2011-1246⟩ Article dans une revue hal-00682913v1
Balanced effect of PACAP and FasL on granule cell death during cerebellar development: a morphological, functional and behavioural characterization. Aurélie Allais,Delphine Burel,Vincent Roy,Sébastien Arthaud,Ludovic Galaset al. Journal of Neurochemistry, 2010, 113 (2), pp.329-40. ⟨10.1111/j.1471-4159.2009.06555.x⟩ Article dans une revue pasteur-00819614v1
Functional remodeling of gap junction-mediated electrical communication between adrenal chromaffin cells in stressed rats. Claude Colomer,Luis A. Olivos Ore,Nathalie Coutry,Marie-Noëlle Mathieu,Sébastien Arthaudet al. Journal of Neuroscience, 2008, 28 (26), pp.6616-26. ⟨10.1523/JNEUROSCI.5597-07.2008⟩ Article dans une revue inserm-00281272v1

Communication dans un congrès (8)

Modelling human REM sleep Behavior Disorder (RBD), a prodromal marker of synucleinopathies, using genetic tools in wild-type mice Blandine Duval,Sébastien Arthaud,Justin Malcey,Amarine Chancel,Luppi Pierre-Hervéet al. Neurofrance 2025, Société Française des Neurosciences (SDN), May 2025, Montpellier, France Communication dans un congrès hal-05119309v1
ALTERATIONS DU SOMMEIL AU COURS DE LA VIE CHEZ DES SOURIS MODELISANT L'ACCUMULATION HUMAINE DE NEUROMELANINE DANS LES NEURONES CATECHOLAMINERGIQUES Sébastien Arthaud,Jean-Christophe Comte,Jiong Liu,Núria Peñuelas,Ariadna Lagunaet al. Le congrès du Sommeil 2025, SFRMS, Nov 2025, Strasbourg, France Communication dans un congrès hal-05347198v1
Réseaux neuronaux de l'atonie musculaire : nouvelles données dans la compréhension fonctionnelle du trouble du comportement en sommeil paradoxal Blandine Duval,Sébastien Arthaud,Justin Malcey,Amarine Chancel,Pierre-Hervé Luppiet al. Le congrès du Sommeil 2025, SFRMS, Nov 2025, Strasbourg, France Communication dans un congrès hal-05347171v1
Modeling EEG data using deep learning for automatic sleep stage classification in mice L. Rose,A.N. Zahid,L. Piilgaard,C.G. Hviid,C.E. Jensenet al. 17th World Sleep Congress, Oct 2023, Rio de Janeiro, Brazil. pp.S411-S412, ⟨10.1016/j.sleep.2023.11.1104⟩ Communication dans un congrès hal-04788391v1
Moderate RBD symptoms in narcoleptic versus IRBD mice. Maxime Grenot,Alexis Roman,Sébastien Arthaud,Paul-Antoine Libourel,Christelle Peyron 17th World Sleep Congress, Oct 2023, Rio de Janeiro, Brazil. pp.S200 Communication dans un congrès hal-04788236v1
Evolution of the sleep-waking cycle in transgenic mice with an age-dependent accumulation of neuromelanin in catecholaminergic neurons, a new humanized model of Parkinson's Disease Sébastien Arthaud,Jiong Liu,Nuria Peñuelas,Ariadana Laguna,Miquel Vilaet al. Forum Federation of European Neuroscience Societies (FENS), Jul 2022, PARIS, France Communication dans un congrès hal-03748322v1
Hypothalamic regulation of REM sleep Luppi Pierre-Hervé,Olivier Clément,Emilie Sapin,Paul-Antoine Libourel,Sébastien Arthaudet al. 21st Congress of the European-Sleep-Research-Society, Sep 2012, Paris, France. pp.2-3 Communication dans un congrès hal-02345917v1
Gliotransmission et sensibilité centrale au glucose : rôle des endozépines Fabrice Morin,Damien Lanfray,Sébastien Arthaud,Johana Ouellet,Vincent Compèreet al. 39ème colloque de la Société de Neuroendocrinologie, Sep 2013, Fès, Maroc Communication dans un congrès hal-02454954v1

Pré-publication, Document de travail (3)

A novel method to study the ecological role of sleep in small mammals Paul-Antoine Libourel,Sebastien Arthaud,Antoine Bergel,Fabrice Bressia,Azzedine Dibet al. 2025 Pré-publication, Document de travail hal-04931921v1
Modelling human brain-wide pigmentation in rodents recapitulates age-related multisystem neurodegenerative deficits Ariadna Laguna,Núria Peñuelas,Marta Gonzalez-Sepulveda,Alba Nicolau,Sébastien Arthaudet al. 2023 Pré-publication, Document de travail hal-04285164v1
Glutamatergic neurons in the lateral periaqueductal gray mediate wakefulness and REM sleep through different pathways Yi-Qun Wang,Lei Li,Jian-Bo Jiang,Sebastien Arthaud,Pierre-Hervé Luppiet al. 2023 Pré-publication, Document de travail hal-04311796v1

Brevet (1)

Agonists of urotensin II receptor for the treatment of vascular dysfunctions during septic choc Vincent Compère,Caroline Marguerite,Pierrick Gandolfo,Sébastien Arthaud,Laurence Desrueset al. France, Patent n° : PCT - N°EP2012/051166. 2012 Brevet hal-02458810v1