Sébastien BROT Research Engineer at University of Poitiers

Identifiants chercheurs

IdHAL :

sebastien-brot

ORCID :

0000-0002-4373-2135

IdRef :

168796082

Présentation

Publications

Article dans une revue (15)

Contribution of tissue clearing and 3D image analysis to in vitro modeling of human cortical development Antoine Retho,Annousha Devi Govindan,Marie-Laure Bonnet,Sébastien Brot,Afsaneh Gaillard Scientific Reports, 2026, ⟨10.1038/s41598-026-41741-7⟩ Article dans une revue hal-05589608v1
Electrophysiological characterisation of intranigral-grafted hiPSC-derived dopaminergic neurons in a mouse model of Parkinson’s disease Bérangère Ballion,Marie-Laure Bonnet,Sébastien Brot,Afsaneh Gaillard Current Stem Cell Research & Therapy, 2025, 16 (1), pp.232. ⟨10.1186/s13287-025-04344-z⟩ Article dans une revue hal-05063750v1
Host-to-graft Propagation of α-synuclein in a Mouse Model of Parkinson’s Disease: Intranigral Versus Intrastriatal Transplantation Maëlig Patrigeon,Sébastien Brot,Marie-Laure Bonnet,Laure Belnoue,Afsaneh Gaillard Transplantation, 2023, 107 (8), p. 201-212. ⟨10.1097/TP.0000000000004565⟩ Article dans une revue hal-04132835v1
Deciphering Brain Metastasis Stem Cell Properties From Colorectal Cancer Highlights Specific Stemness Signature and Shared Molecular Features Amandine Desette,Pierre-Olivier Guichet,Sheik Emambux,Konstantin Masliantsev,Ulrich Corteset al. Cellular and Molecular Gastroenterology and Hepatology, 2023, 16 (5), pp.757-782. ⟨10.1016/j.jcmgh.2023.07.008⟩ Article dans une revue hal-04302791v1
Long-Term Evaluation of Intranigral Transplantation of Human iPSC-Derived Dopamine Neurons in a Parkinson’s Disease Mouse Model Sébastien Brot,Nabila Pyrenina Thamrin,Marie-Laure Bonnet,Maureen Francheteau,Maëlig Patrigeonet al. Cells, 2022, 11 (10), pp.1596. ⟨10.3390/cells11101596⟩ Article dans une revue hal-03682097v1
Beneficial Effects of Hyaluronan-Based Hydrogel Implantation after Cortical Traumatic Injury Anaïs Lainé,Sébastien Brot,Afsaneh Gaillard Cells, 2022, 11 (23), pp.3831. ⟨10.3390/cells11233831⟩ Article dans une revue hal-04132825v1
Better Outcomes with Intranigral versus Intrastriatal Cell Transplantation: Relevance for Parkinson’s Disease Marine Droguerre,Sébastien Brot,Clément Vitrac,Marianne Benoit-Marand,Laure Belnoueet al. Cells, 2022, 11 (7), ⟨10.3390/cells11071191⟩ Article dans une revue hal-03637153v1
Neuroprotective effects of neuropeptide Y against neurodegenerative disease Stéphanie Pain,Sébastien Brot,Afsaneh Gaillard Current Neuropharmacology, 2021, 19, ⟨10.2174/1570159X19666210906120302⟩ Article dans une revue hal-03361423v1
Characterization of Inflammation in Delayed Cortical Transplantation Nissrine Ballout,Tristan Rochelle,Sébastien Brot,Marie-Laure Bonnet,Maureen Francheteauet al. Frontiers in Molecular Neuroscience, 2019, 12, ⟨10.3389/fnmol.2019.00160⟩ Article dans une revue hal-02498268v1
A Delay between Motor Cortex Lesions and Neuronal Transplantation Enhances Graft Integration and Improves Repair and Recovery Sophie Péron,Marine Droguerre,Franck Debarbieux,Nissrine Ballout,Marianne Benoit-Marandet al. Journal of Neuroscience, 2017, 37 (7), pp.1820-1834. ⟨10.1523/JNEUROSCI.2936-16.2017⟩ Article dans une revue hal-02500429v1
Collapsin response-mediator protein 5 (CRMP5) phosphorylation at threonine 516 regulates neurite outgrowth inhibition Sébastien Brot,Hinda Smaoune,Mina Youssef-Issa,Céline Malleval,Claire Benetolloet al. European Journal of Neuroscience, 2014, 40 (7), pp.3010-3020. ⟨10.1111/ejn.12674⟩ Article dans une revue istex hal-02511291v1
Alpha-synuclein spreading in M83 mice brain revealed by detection of pathological α-synuclein by enhanced ELISA Dominique Bétemps,Jérémy Verchère,Sébastien Brot,Eric Morignat,Luc Boussetet al. Acta Neuropathologica Communications, 2013, 2, pp.29. ⟨10.1186/2051-5960-2-29⟩ Article dans une revue hal-01183383v1
Collapsin Response Mediator Protein 5 (CRMP5) Induces Mitophagy Thereby Regulating Mitochondrion Numbers in Dendrites. Sébastien Brot,Carole Auger,Rabia Bentata,Véronique Rogemond,Stéphane Ménigozet al. Journal of Biological Chemistry, 2013, 289, pp.2261-2276. ⟨10.1074/jbc.M113.490862⟩ Article dans une revue hal-00917349v1
Identification of a new CRMP5 isoform present in the nucleus of cancer cells and enhancing their proliferation Sébastien Brot,Céline Malleval,Claire Benetollo,Carole Auger,David Meyronetet al. Experimental Cell Research, 2013, 319 (5), pp.588-599. ⟨10.1016/j.yexcr.2012.12.011⟩ Article dans une revue istex hal-02511307v1
CRMP5 Interacts with Tubulin to Inhibit Neurite Outgrowth, Thereby Modulating the Function of CRMP2 Sébastien Brot,Véronique Rogemond,Valérie Perrot,Naura Chounlamountri,Carole Augeret al. Journal of Neuroscience, 2010, 30 (32), pp.10639-10654. ⟨10.1523/JNEUROSCI.0059-10.2010⟩ Article dans une revue hal-02351827v1

Communication dans un congrès (3)

Three-Dimensional Imaging of Optically Cleared Tissues by Light Sheet Fluorescence Microscopy Sébastien Brot Journée de Microscopie de Poitiers, Jun 2025, Poitiers, France Communication dans un congrès hal-05589630v1
Potential of dopamine neurons derived from human induced pluripotent stem cells reprogrammed by mRNA for Parkinson’s disease Sébastien Brot PHysiopathology Of Parkinson’s disEase » (HOPE), Jan 2020, Paris, France Communication dans un congrès hal-02511362v1
La reprogrammation d’hiPSC par ARNm, une nouvelle approche pour la transplantation de neurones dopaminergiques Sébastien Brot Journée scientifique SFR FED 4226 Neuroimagerie Fonctionnelle, Jun 2017, Poitiers, France Communication dans un congrès hal-02511347v1

Poster de conférence (38)

COMBINATION OF EXERCICE ANS STEM CELL-BASED STRATEGIES TO IMPROVE CORTICAL REPAIR Valentin Fernandez,Annousha Govindan,Marie-Laure Bonnet,Eric Balado,Sébastien Brotet al. 25th biennial meeting of the international society for developmental neuroscience, Sep 2024, Montpellier, France Poster de conférence hal-05517125v1
Functional integration of grafted hiPSC derived dopamine neurons in a mouse model of Parkinson's disease Bérangère Ballion,Marie-Laure Bonnet,Sébastien Brot,Afsaneh Gaillard NeuroFrance 2023, May 2023, Lyon, France Poster de conférence hal-05093772v1
Transplantation of iPSC-derived dopamine neurons in alpha-synuclein overexpression mouse model Laure Belnoue,Maëlig Patrigeon,Marie-Laure Bonnet,Sébastien Brot,Afsaneh Gaillard NeuroFrance 2023, May 2023, Lyon, France Poster de conférence hal-05008254v1
Functional integration of intranigral grafted hiPSC derived dopamine neurons in a mouse model of Parkinson disease Bérangère Ballion,Sébastien Brot,Laure Belnoue,Afsaneh Gaillard FENS Forum 2022, Jul 2022, Paris, France. Poster de conférence hal-04517426v1
Host to graft propagation of alpha-synuclein in Parkinson’s disease: intra-nigral versus intra-striatal transplantation Maëlig Patrigeon,Sébastien Brot,Marie-Laure Bonnet,Laure Belnoue,Afsaneh Gaillard 13th FENS Forum of Neuroscience, Jul 2022, Paris, France Poster de conférence hal-05008798v1
Potential of dopamine neurons derived from human induced pluripotent stem cells reprogrammed by mRNA for Parkinson’s disease Sébastien Brot,Marie-Laure Bonnet,Bérangère Ballion,Maëlig Patrigeon,Maureen Francheteauet al. 13th FENS Forum of Neuroscience, Jul 2022, Paris, France Poster de conférence hal-05008791v1
Biomaterials to enhance the integration of grafted human iPSC-derived motor cortical neurons in a mice model of traumatic injury Oriane Rabesandratana,Anaïs Lainé,Marie-Laure Bonnet,Laure Belnoue,Sébastien Brotet al. FSSCR annual meeting 2021, Nov 2021, Montpellier, France Poster de conférence hal-03489108v1
Potential of dopamine neurons derived from human induced pluripotent stem cells reprogrammed by mRNA for Parkinson’s disease Sébastien Brot,Marie-Laure Bonnet,Bérangère Ballion,Maëlig Patrigeon,Maureen Francheteauet al. 31st Annual meeting of the Network for European CNS Transplantation and Restoration (NECTAR), Nov 2021, Edinburgh, France. Poster de conférence hal-03637185v1
Potential of dopamine neurons derived from human induced pluripotent stem cells reprogrammed by mRNA for Parkinson’s disease Sébastien Brot,Marie-Laure Bonnet,Maëlig Patrigeon,Maureen Francheteau,Laure Belnoueet al. NeuroFrance 2021, May 2021, Strasbourg, France Poster de conférence hal-03221124v1
Potential of dopamine neurons derived from human induced pluripotent stem cells reprogrammed by mRNA for Parkinson’s disease Sébastien Brot,Marie-Laure Bonnet,Bérangère Ballion,Maëlig Patrigeon,Maureen Francheteauet al. 31st Annual meeting of the Network for European CNS Transplantation and Restoration (NECTAR), Nov 2021, Edinburg, United Kingdom Poster de conférence hal-05008766v1
Modelling Parkinson´s disease with patient induced pluripotent stem cells Nabila Pyrenina Thamrin,Marie-Laure Bonnet,Maëlig Patrigeon,Laure Belnoue,Jean Christophe C Corvolet al. NeuroFrance 2021, May 2021, Strasbourg, France Poster de conférence hal-03221486v1
Functional integration of grafted hiPSC derived dopamine neurons in a murine model of Parkinson's disease Bérangère Ballion,Laure Belnoue,Sébastien Brot,Afsaneh Gaillard NeuroFrance 2021, May 2021, Strasbourg, France Poster de conférence hal-03405614v1
Therapeutic effects of hyaluronan-based hydrogel after cortical traumatic injury Anaïs Lainé,Sébastien Brot,Oriane Rabesandratana,Afsaneh Gaillard NeuroFrance 2021, May 2021, Strasbourg, France Poster de conférence hal-03221468v1
Host to graft propagation of α-synuclein in Parkinson’s disease: intra-nigral versus intra-striatal transplantation. Maëlig Patrigeon,Sébastien Brot,Marie-Laure Bonnet,Laure Belnoue,Afsaneh Gaillard NeuroFrance 2021, May 2021, Strasbourg, France Poster de conférence hal-03221475v1
The potential of motor cortical neurons derived hiPSC transplantation for brain repair following traumatic brain injury Laure Belnoue,Hammam I. El Hajj,Marie-Laure Bonnet,Sébastien Brot,Afsaneh Gaillard NeuroFrance 2021, May 2021, Strasbourg, France Poster de conférence hal-03221118v1
Potential of dopamine neurons derived from human induced pluripotent stem cells reprogrammed by mRNA for Parkinson’s disease Sébastien Brot,Marie-Laure Bonnet,Maureen Francheteau,Laure Belnoue,Afsaneh Gaillard PHysiopathology Of Parkinson’s disEase » (HOPE), Jan 2020, Paris, France Poster de conférence hal-02511393v1
Absence of interleukin 33 impaired axonal outgrowth of grafted cortical neurons. Anaïs Lainé,Nissrine Ballout,Marie Droguerre,Sébastien Brot,Maureen Francheteauet al. NeuroFrance, the international conference of the french society of Neuroscience, May 2019, Marseille, France Poster de conférence hal-02547007v1
The potential of motor cortical neurons derived hiPSC transplantation for brain repair following traumatic brain injury Hammam L El Hajj,Laure Belnoue,Marie-Laure Bonnet,Sébastien Brot,Afsaneh Gaillard Neurofrance, Jun 2019, Marseille, France Poster de conférence hal-02516060v1
Potential of dopamine neurons derived from human induced pluripotent stem cells reprogrammed by mRNA for Parkinson’s disease Sébastien Brot,Marie-Laure Bonnet,Maureen Francheteau,Afsaneh Gaillard FSSCR 3rd Annual Meeting, Nov 2019, Lyon, France Poster de conférence hal-02512692v1
Potential of dopamine neurons derived from human induced pluripotent stem cells reprogrammed by mRNA for Parkinson’s disease Sébastien Brot,Marie-Laure Bonnet,Maureen Francheteau,Afsaneh Gaillard From 3D culture to organoïds - AVIESAN, Dec 2019, Paris, France Poster de conférence hal-02512008v1
Potential of dopamine neurons derived from human induced pluripotent stem cells reprogrammed by mRNA for Parkinson’s disease Sébastien Brot,Marie-Laure Bonnet,Maureen Francheteau,Afsaneh Gaillard LE STUDIUM CONFERENCE : Induced Pluripotent Stem Cells (iPSCs): From Disease Models to Mini-Organs, Jan 2019, Tours, France Poster de conférence hal-02512709v1
Potential of dopamine neurons derived from human induced pluripotent stem cells reprogrammed by mRNA for Parkinson’s disease Sébastien Brot,Marie-Laure Bonnet,Maureen Francheteau,Afsaneh Gaillard 11th FENS Forum of Neuroscience, Jul 2018, Berlin, Germany Poster de conférence hal-02512713v1
Differentiation of human iPSC into neurons of motor cortex and grafting into injured motor cortex of adult mice Hammam L El Hajj,Sébastien Brot,Marie-Laure Bonnet,Afsaneh Gaillard 11th FENS forum of Neurosciences, Jul 2018, Berlin, Germany Poster de conférence hal-02516097v1
Potential of dopamine neurons derived from human induced pluripotent stem cells reprogrammed by mRNA for Parkinson’s disease Sébastien Brot,Marie-Laure Bonnet,Maureen Francheteau,Afsaneh Gaillard Symposium "(Re)Constructing the nervous system: stem cells and beyond" Institut fer à Moulin, Sep 2017, Paris, France Poster de conférence hal-02516028v1
Dopamine neurons derived from human induced pluripotent stem cell reprogrammed by mRNA Sébastien Brot,Marie-Laure Bonnet,Maureen Francheteau,Afsaneh Gaillard Neurofrane, May 2017, Bordeaux, France Poster de conférence hal-02516038v1
Beneficial effects of inflammation in delayed cortical transplantation Nissrine Ballout,Tristan Rochelle,Sébastien Brot,Maureen Francheteau,Jean-Marc Gombertet al. Neurofrance, May 2017, Bordeaux, France Poster de conférence hal-02517467v1
Molecular and cellular alterations underlying motor disorders in autism spectrum disorders mouse models Obélia Haida,Tareq Al Sagheer,Anais Balbous,Sébastien Brot,Maureen Francheteauet al. Séminaire thématique bio-santé ED 524, Mar 2016, Pouligny-Notre-Dame, France Poster de conférence hal-02556995v1
Study of Neuroinflammation after cortical lesion and transplantation with or without delay Nissrine Ballout,Tristan Rochelle,Sébastien Brot,Maureen Francheteau,Jean-Marc Gombertet al. Plasticité cérébrale, de la recherche fondamentale à la clinique 2e Journées Thématiques de la société des Neurosciences, May 2016, Tours, France Poster de conférence hal-02517855v1
Production and characterization of dopaminergic neurons derived from mouse embryonic stem cells Sandie Brisson,Bhaskar Saha,Tristan Rochelle,Sébastien Brot,Marie-Laure Bonnetet al. Plasticité cérébrale, de la recherche fondamentale à la clinique - 2e Journées Thématiques de la société des neurosciences, May 2016, Tours, France Poster de conférence hal-02517846v1
Production and characterization of dopaminergic neurons derived from mouse embryonic stem cells Sébastien Brot,Sandie Brisson,Bhaskar Saha,Tristan Rochelle,Marie-Laure Bonnetet al. 3ème Journée Scientifique de la SFR Tours-Poitiers, Jun 2015, Tours, France Poster de conférence hal-02517803v1
Study of Neuroinflammation after cortical lesion and transplantation with or without delay Nissrine Ballout,Tristan Rochelle,Sébastien Brot,Maureen Francheteau,Jean-Marc Gombertet al. 12e colloque de la société des Neurosciences, May 2015, Montpellier, France Poster de conférence hal-02517504v1
Delaying cortical transplantation improves the outcome of the graft Afsaneh Gaillard,Sophie Péron,Marine Droguerre,Nissrine Ballout,Sébastien Brotet al. 9th FENS Forum of Neuroscience, Jul 2014, Milan, Italy Poster de conférence hal-02517797v1
Nigrostriatal pathway reconstruction by transplanting embryonic stem cell-derived dopaminergic neurons in Parkinson’s disease Tristan Rochelle,Sandie Brisson,Sébastien Brot,Marie-Laure Bonnet,Marine Droguerreet al. 2ème Journée Scientifique de la SFR Tours-Poitiers, Jun 2014, Poitiers, France Poster de conférence hal-02517734v1
Production and characterization of dopaminergic neurons derived from mouse embryonic stem cells Sandie Brisson,Bhaskar Saha,Tristan Rochelle,Sébastien Brot,Marie-Laure Bonnetet al. Journée de recherche Tours-Poitiers-Limoges, Jan 2014, Tours, France Poster de conférence hal-02517712v1
Collapsin Response Mediator Protein 5, a multifunction protein involved in neuronal polarity and mitochondrial machinery Sébastien Brot,Carole Auger,Véronique Rogemond,Jérome Honnorat,Mahnaz Moradi-Améli 7th FENS Forum of European Neuroscience, Jul 2010, Amsterdam, Netherlands Poster de conférence hal-02518829v1
Differential localization of CRMP5 in cancer cells compared to normal condition Sébastien Brot,Claire Benetollo,Celine Malleval,Jérome Honnorat 5ème journée scientifique du CLARA "Cancéropôle Lyon Auvergne Rhône-Alpes", Mar 2010, Lyon, France Poster de conférence hal-02518843v1
Identification of a direct interaction between CRMP5 and tubulin involved in neurite outgrowth inhibition Sébastien Brot,Véronique Rogemond,Valérie Perrot,Naura Chounlamountri,Carole Augeret al. 9ème Colloque de la société des Neurosciences, May 2009, Bordeaux, France Poster de conférence hal-02518885v1
Study of CRMP5 properties and its role in the development of cerebral tumors Sébastien Brot,Celine Malleval,Jérome Honnorat,Mahnaz Moradi-Améli 3ème journée scientifique du CLARA "Cancéropôle Lyon Auvergne Rhône-Alpes", Mar 2008, Lyon, France Poster de conférence hal-02518895v1