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Serge Candéias

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Early effects of different brain radiotherapy modalities on circulating leucocyte subpopulations in rodents

Thao-Nguyen Pham , Julie Coupey , Jérôme Toutain , Serge M Candéias , Gaël Simonin
International Journal of Radiation Biology, 2024, pp.1 - 12. ⟨10.1080/09553002.2024.2324471⟩
Article dans une revue hal-04504965v1
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Bystander signals from low- and high-dose irradiated human primary fibroblasts and keratinocytes modulate the inflammatory response of peripheral blood mononuclear cells

Isabelle Testard , Garcia-Chartier, Elizabeth , Amani Issa , Véronique Collin-Faure , Catherine Aude-Garcia
Journal of Radiation Research, 2023, ⟨10.1093/jrr/rrac094⟩
Article dans une revue hal-04016753v1
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Sex- and age-specific aspects of human peripheral T-cell dynamics

Justyna Mika , Kengo Yoshida , Kusunoki, Yoichiro , Serge M. Candéias , Joanna Polanska
Frontiers in Immunology, 2023, 14, pp.1224304. ⟨10.3389/fimmu.2023.1224304⟩
Article dans une revue hal-04282651v1
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Deficient Radiation Transcription Response in COVID-19 Patients

Stanislav Polozov , Lourdes Cruz-Garcia , Grainne O'Brien , Veronika Goriacha , Farah Nasser
Advances in Radiation Oncology, 2023, 8 (4), pp.101215. ⟨10.1016/j.adro.2023.101215⟩
Article dans une revue hal-04199354v1
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Establishing mechanisms affecting the individual response to ionising radiation

Dietrich Averbeck , Serge M. Candéias , Sudhir Chandna , Nicolas Foray , Anna Friedl
International Journal of Radiation Biology, 2020, 96 (3), pp.297-323. ⟨10.1080/09553002.2019.1704908⟩
Article dans une revue hal-02431625v1
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Systemic modulation of stress and immune parameters in patients treated for prostate adenocarcinoma by intensity-modulated radiation therapy or stereotactic ablative body radiotherapy

B. Frey , J. Mika , K. Jelonek , L. Cruz-Garcia , C. Roelants
Strahlentherapie und Onkologie, 2020, 196 (11), pp.‏ 1018-1033. ⟨10.1007/s00066-020-01637-5⟩
Article dans une revue hal-02892711v1
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Germline DNA Retention in Murine and Human Rearranged T Cell Receptor Gene Coding Joints: Alternative Recombination Signal Sequences and V(D)J Recombinase Errors

Justyna Mika , Sylwia Kabacik , Christophe Badie , Joanna Polanska , Serge M. Candéias
Frontiers in Immunology, 2019, 10, pp.2637. ⟨10.3389/fimmu.2019.02637⟩
Article dans une revue hal-02431623v1

Influence of Confounding Factors on Radiation Dose Estimation Using In Vivo Validated Transcriptional Biomarkers.

Lourdes Cruz-Garcia , O’brien, Grainne , Ellen Donovan , Lone Gothard , Sue Boyle
Health Physics, 2018, 115 (1), pp.90-101. ⟨10.1097/HP.0000000000000844⟩
Article dans une revue hal-01799318v1

Editorial: Radiation and the Immune System: Current Knowledge and Future Perspectives

Katalin Lumniczky , Serge M. Candéias , Udo Gaipl , Benjamin Frey
Frontiers in Immunology, 2018, 8
Article dans une revue hal-01948347v1

Ionizing radiation does not impair the mechanisms controlling genetic stability during T cell receptor gene rearrangement in mice.

Serge M. Candéias , Sylwia Kabacik , Ann-Karin Olsen , Dag M. Eide , Dag A. Brede
International Journal of Radiation Biology, 2018, 94 (4), pp.357-365. ⟨10.1080/09553002.2018.1439195⟩
Article dans une revue hal-01726683v1
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Combining PARP inhibition, radiation, and immunotherapy: A possible strategy to improve the treatment of cancer?

Mathieu Césaire , Juliette Thariat , Serge M. Candéias , Dinu Stefan , Yannick Saintigny
International Journal of Molecular Sciences, 2018, 19 (12), pp.3793. ⟨10.3390/ijms19123793⟩
Article dans une revue hal-01948336v1

Low-dose radiation accelerates aging of the T-cell receptor repertoire in CBA/Ca mice.

Serge M. Candéias , Justyna Mika , Paul Finnon , Tom Verbiest , Rosemary Finnon
Cellular and Molecular Life Sciences, 2017, 74 (23), pp. 4339-4351 ⟨10.1007/s00018-017-2581-2⟩
Article dans une revue hal-01625357v1

The Immune System in Cancer Prevention, Development and Therapy

Serge M. Candéias , Udo S. Gaipl
Anti-Cancer Agents in Medicinal Chemistry, 2016, 16 (1), pp.101-107. ⟨10.2174/1871520615666150824153523⟩
Article dans une revue hal-01272145v1

Key mechanisms involved in ionizing radiation-induced systemic effects. A current review

Ifigeneia V. Mavragani , Danae A. Laskaratou , Benjamin Frey , Serge M. Candéias , Katalin Lumniczky
Toxicology Research, 2016, 5 (1), pp.12-33. ⟨10.1039/c5tx00222b⟩
Article dans une revue hal-01272209v1

The many interactions between the innate immune system and the response to radiation

Serge M. Candéias , Isabelle Testard
Cancer Letters, 2015, 368 (2), pp.173-178. ⟨10.1016/j.canlet.2015.02.007⟩
Article dans une revue hal-01212298v1

Developmental regulation of p53-dependent radiation-induced thymocyte apoptosis in mice

A. Gentil Dit Maurin , C. Lemercier , V. Collin-Faure , P.N. Marche , E. Jouvin-Marche
Clinical and Experimental Immunology, 2015, 179 (1), pp.30-38. ⟨10.1111/cei.12329⟩
Article dans une revue hal-01169410v1

The toxicity redox mechanisms of cadmium alone or together with copper and zinc homeostasis alteration: its redox biomarkers.

Yves Nzengue , Serge M. Candéias , Sylvie Sauvaigo , Thierry Douki , Alain Favier
Journal of Trace Elements in Medicine and Biology, 2011, 25 (3), pp.171-80. ⟨10.1016/j.jtemb.2011.06.002⟩
Article dans une revue hal-01070481v1
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Enhanced susceptibility of T lymphocytes to oxidative stress in the absence of the cellular prion protein.

Catherine Aude-Garcia , Christian Villiers , Serge M. Candéias , Catherine Garrel , Caroline Bertrand
Cellular and Molecular Life Sciences, 2011, 68 (4), pp.687-96. ⟨10.1007/s00018-010-0477-5⟩
Article dans une revue hal-00510679v1
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Distinct effects of DNA-PKcs and Artemis inactivation on signal joint formation in vivo.

Cédric Touvrey , Chrystelle Couedel , Pauline Soulas-Sprauel , Rachel Couderc , Maria Jasin
Molecular Immunology, 2008, 45 (12), pp.3383-91. ⟨10.1016/j.molimm.2008.04.004⟩
Article dans une revue hal-00271618v1

Distinct effects of DNA-PKcs and Artemis inactivation on signal joint formation in vivo

Cédric Touvrey , Chrystelle Couedel , Pauline Soulas , Rachel Couderc , Maria Jasin
Molecular Immunology, 2008, 45 (12), pp.3383-3391
Article dans une revue hal-01948376v1

Cadmium and T cell differentiation: Limited impact in vivo but significant toxicity in fetal thymus organ culture

Muriel Viau , V. Collin-Faure , P. Richaud , J.-L. Ravanat , Serge M. Candéias
Toxicology and Applied Pharmacology, 2007, 223 (3), pp.257-266. ⟨10.1016/j.taap.2007.05.017⟩
Article dans une revue hal-01948381v1

Gene-specific signal joint modifications during V(D)J recombination of TCRAD locus genes in murine and human thymocytes

Cédric Touvrey , Eve Borel , Patrice N. Marche , Evelyne Jouvin-Marche , Serge M. Candéias
Immunobiology, 2006, 211 (9), pp.741-751. ⟨10.1016/j.imbio.2006.04.001⟩
Article dans une revue hal-01948389v1

Reassignment of the murine 3′TRDD1 recombination signal sequence

S Touvrey , L. Cowell , E Lieberman , P. Marche , E. Jouvin-Marche
Immunogenetics, 2006, 58 (11), pp.895-903. ⟨10.1007/s00251-006-0150-1⟩
Article dans une revue hal-01948384v1
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Reassignment of the murine 3'TRDD1 recombination signal sequence.

Cédric Touvrey , Lindsay G. Cowell , Ann E. Lieberman , Patrice N. Marche , Evelyne Jouvin-Marche
Immunogenetics, 2006, 58 (11), pp.895-903. ⟨10.1007/s00251-006-0150-1⟩
Article dans une revue inserm-00089245v1

p53-dependent and p53-independent pathways for radiation-induced immature thymocyte differentiation

Serge M. Candéias , Stéphane Jean Charles Mancini , Cédric Touvrey , Eve Borel , Evelyne Marche
Oncogene, 2004, 23 (10), pp.1922-1929. ⟨10.1038/sj.onc.1207320⟩
Article dans une revue hal-01948396v1

Unrepaired cyclobutane pyrimidine dimers do not prevent proliferation of UV-B-irradiated cultured human fibroblasts.

Sophie Courdavault , Caroline Baudouin , Sylvie Sauvaigo , Stephane Mouret , Serge M. Candéias
Photochemistry and Photobiology, 2004, 79 (2), pp.145-51
Article dans une revue hal-01949083v1

T lymphocytes potentiate murine dendritic cells to produce IL-12.

Alexandra Rizzitelli , Rolande Berthier , Véronique Collin , Serge M. Candéias , Patrice N. Marche
Journal of Immunology, 2002, 169 (8), pp.4237-45
Article dans une revue hal-01948399v1

TCRA gene rearrangement in immature thymocytes in absence of CD3, pre-TCR, and TCR signaling.

E. Mancini , Serge M. Candéias , P Di Santo , P. Ferrier , P. Marche
Journal of Immunology, 2001, 167 (8), pp.4485-93
Article dans une revue hal-01948404v1

TCR alpha-chain repertoire in pTalpha-deficient mice is diverse and developmentally regulated: implications for pre-TCR functions and TCRA gene rearrangement.

E. Mancini , Serge M. Candéias , H Fehling , H von Boehmer , E Marche
Journal of Immunology, 1999, 163 (11), pp.6053-9
Article dans une revue hal-01948407v1

Differential chronology of TCRADV2 gene use by $\alpha$ and $\delta$ chains of the mouse TCR

Evelyne Jouvin-Marche , Catherine Aude-Garcia , Serge M. Candéias , Eve Borel , Soulef Hachemi-Rachedi
European Journal of Immunology, 1998, 28 (3), pp.818-827. ⟨10.1002/(SICI)1521-4141(199803)28:03<818::AID-IMMU818>3.0.CO;2-0⟩
Article dans une revue hal-01949099v1

Use of TCR ADV gene segments by the δ chain is independent of their position and of CD3 expression

E Gallagher , C Candéias , M Martinon , Eve Borel , Marie Malissen
European Journal of Immunology, 1998, 28 (11), pp.3878-3885. ⟨10.1002/(SICI)1521-4141(199811)28:11<3878::AID-IMMU3878>3.0.CO;2-C⟩
Article dans une revue hal-01949096v1

Interleukin 7 receptor control of T cell receptor gamma gene rearrangement: role of receptor-associated chains and locus accessibility.

K Durum , Serge M. Candéias , H. Nakajima , L Leonard , A Baird
Journal of Experimental Medicine, 1998, 188 (12), pp.2233-41
Article dans une revue hal-01949093v1

IL-7 receptor and VDJ recombination: trophic versus mechanistic actions.

Serge M. Candéias , Kathrin Muegge , Scott K. Durum
Immunity, 1997, 6 (5), pp.501-8
Article dans une revue hal-01949113v1

IL-7 activates alpha4beta1 integrin in murine thymocytes.

S Kitazawa , M Muegge , R Badolato , J. Wang , W Fogler
Journal of Immunology, 1997, 159 (5), pp.2259-64
Article dans une revue hal-01949103v1

Defective T-cell receptor gamma gene rearrangement in interleukin-7 receptor knockout mice.

Serge M. Candéias , J Peschon , K Muegge , S Durum
Immunology Letters, 1997, 57 (1-3), pp.9-14
Article dans une revue hal-01949109v1

p53-dependent apoptosis and transcription of p21waf/cip1/sdi1 in SCID mice following gamma-irradiation.

Serge M. Candéias , K Durum , K Muegge
Biochimie, 1997, 79 (9-10), pp.607-12
Article dans une revue hal-01948420v1

Junctional diversity in signal joints from T cell receptor beta and delta loci via terminal deoxynucleotidyl transferase and exonucleolytic activity.

Serge M. Candéias , K Muegge , S Durum
Journal of Experimental Medicine, 1996, 184 (5), pp.1919-26
Article dans une revue hal-01949115v1

A novel putative helicase produced in early murine lymphocytes.

S. Jarvis , T Geiman , S Vila-Storm , O Osipovich , U Akella
Gene, 1996, 169 (2), pp.203-7
Article dans une revue hal-01949117v1

Expression of FcγRIII defines distinct subpopulations of fetal liver B cell and myeloid precursors

U Carlsson , Serge M. Candéias , Uwe Staerz , Gordon Keller , Leif Carlsson
European Journal of Immunology, 1995, 25 (8), pp.2308-2317. ⟨10.1002/eji.1830250829⟩
Article dans une revue hal-01949118v1

T cell receptor Vβ8.2 gene germ-line transcription: An early event of lymphocyte differentiation

R Candéias , Richard Hardy , Yue Sheng Li , Uwe Staerz , Serge M. Candéias
European Journal of Immunology, 1994, 24 (12), pp.3073-3081. ⟨10.1002/eji.1830241224⟩
Article dans une revue hal-01949119v1

Islet-specific T-cell clones from nonobese diabetic mice express heterogeneous T-cell receptors.

Serge M. Candéias , C Candéias , K Katz , C. Benoist , D Mathis
Proceedings of the National Academy of Sciences of the United States of America, 1991, 88 (14), pp.6167-70
Article dans une revue hal-01949123v1
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The V$_\beta$ 17$^+$ T cell repertoire: skewed J$\beta$ usage after thymic selection; dissimilar CDR3s in CD4$^+$ versus CD8$^+$ cells.

Serge M. Candéias , Caroline Waltzinger , Christophe Benoist , Diane Mathis
Journal of Experimental Medicine, 1991, 174 (5), pp.989-1000
Article dans une revue hal-01949122v1

NF-X, a transcription factor implicated in MHC class II gene regulation.

V Kouskoff , R Mantovani , Serge M. Candéias , A Staub , B Lisowska-Grospierre
Journal of Immunology, 1991, 146 (9), pp.3197-204
Article dans une revue hal-01949125v1

A special repertoire of $\alpha$:$\beta$ T cells in neonatal mice.

M. Bogue , Serge M. Candéias , C. Benoist , D. Mathis
EMBO Journal, 1991, 10 (12), pp.3647-3654
Article dans une revue hal-01949121v1

An enhancer factor defect in a mutant Burkitt lymphoma cell line.

Werner Koch , Serge M. Candéias , John Guardiola , Roberto Accolla , Christophe Benoist
Journal of Experimental Medicine, 1988, 167 (6), pp.1781-90
Article dans une revue hal-01949126v1

Long-term immunomodulatory effects of radiation exposure

Serge M. Candéias
46th Annual Meeting of the European Radiation Research Society (ERRS 2021), Nov 2021, Caen, France
Communication dans un congrès hal-03578728v1

Long-term immuno-modulatory effects of ionizing radiation

Serge M. Candéias
46th Annual Meeting of the European Radiation Research Society (ERRS-2021), Nov 2021, Caen, Université de Caen-Normandie(Présentiel), France
Communication dans un congrès hal-04511538v1
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Effects of nanoparticles on murine macrophages

Mireille Chevallet , Catherine Aude-Garcia , Cécile Lelong , Serge M. Candéias , Sylvie Luche
Nanosafe2010: International Conference on Safe Production and Use of Nanomaterials 16-18 November 2010, Grenoble, France, Nov 2010, Grenoble, France. pp.12034, ⟨10.1088/1742-6596/304/1/012034⟩
Communication dans un congrès hal-00607201v1