Serge Candéias

Documents

Publications

Mammary intraepithelial lymphocytes and intestinal inputs shape T cell dynamics in lactogenesis

Abigail Jaquish , Eleni Phung , Xutong Gong , Pilar Baldominos , Silvia Galván-Peña et al.

Nature Immunology, 2025, 26, pp.1411-1422. ⟨10.1038/s41590-025-02218-3⟩

Article dans une revue hal-05296415v1

A comprehensive evaluation of diversity measures for TCR repertoire profiling

Justyna Mika , Alicja Polanska , Kim R. M. Blenman , Lajos Pusztai , Joanna Polanska et al.

BMC Biology, 2025, 23 (1), pp.133. ⟨10.1186/s12915-025-02236-5⟩

Article dans une revue hal-05151289v1

Effect of glioblastoma and brain radiotherapy on T-lymphocyte subpopulations in rodents

Thao-Nguyen Pham , Julie Coupey , Florian Yger , Serge M. Candéias , Juliette Thariat et al.

Radiotherapy & Oncology, 2025, 206, pp.110801. ⟨10.1016/j.radonc.2025.110801⟩

Article dans une revue hal-05151385v1

Genomic specificity of anti-mouse TCR mAbs determined by single-cell RNAseq

Ian Magill , Val Piekarsa , Sofia Kossida , Josh Croteau , Amy Lee et al.

Journal of Immunology, 2025, 214 (9), pp.2202-2210. ⟨10.1093/jimmun/vkaf094⟩

Article dans une revue hal-05304390v1

Early effects of different brain radiotherapy modalities on circulating leucocyte subpopulations in rodents

Thao-Nguyen Pham , Julie Coupey , Jérôme Toutain , Serge M Candéias , Gaël Simonin et al.

International Journal of Radiation Biology, 2024, 100 (5), pp.744-755. ⟨10.1080/09553002.2024.2324471⟩

Article dans une revue hal-04504965v1

Deficient Radiation Transcription Response in COVID-19 Patients

Stanislav Polozov , Lourdes Cruz-Garcia , Grainne O'Brien , Veronika Goriacha , Farah Nasser et al.

Advances in Radiation Oncology, 2023, 8 (4), pp.101215. ⟨10.1016/j.adro.2023.101215⟩

Article dans une revue hal-04199354v1

Bystander signals from low- and high-dose irradiated human primary fibroblasts and keratinocytes modulate the inflammatory response of peripheral blood mononuclear cells

Isabelle Testard , Garcia-Chartier, Elizabeth , Amani Issa , Véronique Collin-Faure , Catherine Aude-Garcia et al.

Journal of Radiation Research, 2023, ⟨10.1093/jrr/rrac094⟩

Article dans une revue hal-04016753v1

Sex- and age-specific aspects of human peripheral T-cell dynamics

Justyna Mika , Kengo Yoshida , Kusunoki, Yoichiro , Serge M. Candéias , Joanna Polanska

Frontiers in Immunology, 2023, 14, pp.1224304. ⟨10.3389/fimmu.2023.1224304⟩

Article dans une revue hal-04282651v1

Systemic modulation of stress and immune parameters in patients treated for prostate adenocarcinoma by intensity-modulated radiation therapy or stereotactic ablative body radiotherapy

B. Frey , J. Mika , K. Jelonek , L. Cruz-Garcia , C. Roelants et al.

Strahlentherapie und Onkologie, 2020, 196 (11), pp.‏ 1018-1033. ⟨10.1007/s00066-020-01637-5⟩

Article dans une revue hal-02892711v1

Establishing mechanisms affecting the individual response to ionising radiation

Dietrich Averbeck , Serge M. Candéias , Sudhir Chandna , Nicolas Foray , Anna Friedl et al.

International Journal of Radiation Biology, 2020, 96 (3), pp.297-323. ⟨10.1080/09553002.2019.1704908⟩

Article dans une revue hal-02431625v1

Germline DNA Retention in Murine and Human Rearranged T Cell Receptor Gene Coding Joints: Alternative Recombination Signal Sequences and V(D)J Recombinase Errors

Justyna Mika , Sylwia Kabacik , Christophe Badie , Joanna Polanska , Serge M. Candéias

Frontiers in Immunology, 2019, 10, pp.2637. ⟨10.3389/fimmu.2019.02637⟩

Article dans une revue hal-02431623v1

Combining PARP inhibition, radiation, and immunotherapy: A possible strategy to improve the treatment of cancer?

Mathieu Césaire , Juliette Thariat , Serge M. Candéias , Dinu Stefan , Yannick Saintigny et al.

International Journal of Molecular Sciences, 2018, 19 (12), pp.3793. ⟨10.3390/ijms19123793⟩

Article dans une revue hal-01948336v1

Influence of Confounding Factors on Radiation Dose Estimation Using In Vivo Validated Transcriptional Biomarkers.

Lourdes Cruz-Garcia , O’brien, Grainne , Ellen Donovan , Lone Gothard , Sue Boyle et al.

Health Physics, 2018, 115 (1), pp.90-101. ⟨10.1097/HP.0000000000000844⟩

Article dans une revue hal-01799318v1

Ionizing radiation does not impair the mechanisms controlling genetic stability during T cell receptor gene rearrangement in mice.

Serge M. Candéias , Sylwia Kabacik , Ann-Karin Olsen , Dag M. Eide , Dag A. Brede et al.

International Journal of Radiation Biology, 2018, 94 (4), pp.357-365. ⟨10.1080/09553002.2018.1439195⟩

Article dans une revue hal-01726683v1

Editorial: Radiation and the Immune System: Current Knowledge and Future Perspectives

Katalin Lumniczky , Serge M. Candéias , Udo Gaipl , Benjamin Frey

Frontiers in Immunology, 2018, 8

Article dans une revue hal-01948347v1

Low-dose radiation accelerates aging of the T-cell receptor repertoire in CBA/Ca mice.

Serge M. Candéias , Justyna Mika , Paul Finnon , Tom Verbiest , Rosemary Finnon et al.

Cellular and Molecular Life Sciences, 2017, 74 (23), pp. 4339-4351 ⟨10.1007/s00018-017-2581-2⟩

Article dans une revue hal-01625357v1

The Immune System in Cancer Prevention, Development and Therapy

Serge M. Candéias , Udo S. Gaipl

Anti-Cancer Agents in Medicinal Chemistry, 2016, 16 (1), pp.101-107. ⟨10.2174/1871520615666150824153523⟩

Article dans une revue istex hal-01272145v1

Key mechanisms involved in ionizing radiation-induced systemic effects. A current review

Ifigeneia V. Mavragani , Danae A. Laskaratou , Benjamin Frey , Serge M. Candéias , Katalin Lumniczky et al.

Toxicology Research, 2016, 5 (1), pp.12-33. ⟨10.1039/c5tx00222b⟩

Article dans une revue hal-01272209v1

Developmental regulation of p53-dependent radiation-induced thymocyte apoptosis in mice

A. Gentil Dit Maurin , C. Lemercier , V. Collin-Faure , P.N. Marche , E. Jouvin-Marche et al.

Clinical and Experimental Immunology, 2015, 179 (1), pp.30-38. ⟨10.1111/cei.12329⟩

Article dans une revue hal-01169410v1

The many interactions between the innate immune system and the response to radiation

Serge M. Candéias , Isabelle Testard

Cancer Letters, 2015, 368 (2), pp.173-178. ⟨10.1016/j.canlet.2015.02.007⟩

Article dans une revue istex hal-01212298v1

Enhanced susceptibility of T lymphocytes to oxidative stress in the absence of the cellular prion protein.

Catherine Aude-Garcia , Christian Villiers , Serge M. Candéias , Catherine Garrel , Caroline Bertrand et al.

Cellular and Molecular Life Sciences, 2011, 68 (4), pp.687-96. ⟨10.1007/s00018-010-0477-5⟩

Article dans une revue hal-00510679v1

The toxicity redox mechanisms of cadmium alone or together with copper and zinc homeostasis alteration: its redox biomarkers.

Yves Nzengue , Serge M. Candéias , Sylvie Sauvaigo , Thierry Douki , Alain Favier et al.

Journal of Trace Elements in Medicine and Biology, 2011, 25 (3), pp.171-80. ⟨10.1016/j.jtemb.2011.06.002⟩

Article dans une revue istex hal-01070481v1

Distinct effects of DNA-PKcs and Artemis inactivation on signal joint formation in vivo

Cédric Touvrey , Chrystelle Couedel , Pauline Soulas , Rachel Couderc , Maria Jasin et al.

Molecular Immunology, 2008, 45 (12), pp.3383-3391

Article dans une revue hal-01948376v1

Distinct effects of DNA-PKcs and Artemis inactivation on signal joint formation in vivo.

Cédric Touvrey , Chrystelle Couedel , Pauline Soulas-Sprauel , Rachel Couderc , Maria Jasin et al.

Molecular Immunology, 2008, 45 (12), pp.3383-91. ⟨10.1016/j.molimm.2008.04.004⟩

Article dans une revue hal-00271618v1

Cadmium and T cell differentiation: Limited impact in vivo but significant toxicity in fetal thymus organ culture

Muriel Viau , V. Collin-Faure , P. Richaud , J.-L. Ravanat , Serge M. Candéias

Toxicology and Applied Pharmacology, 2007, 223 (3), pp.257-266. ⟨10.1016/j.taap.2007.05.017⟩

Article dans une revue istex hal-01948381v1

Reassignment of the murine 3'TRDD1 recombination signal sequence.

Cédric Touvrey , Lindsay G. Cowell , Ann E. Lieberman , Patrice N. Marche , Evelyne Jouvin-Marche et al.

Immunogenetics, 2006, 58 (11), pp.895-903. ⟨10.1007/s00251-006-0150-1⟩

Article dans une revue inserm-00089245v1

Gene-specific signal joint modifications during V(D)J recombination of TCRAD locus genes in murine and human thymocytes

Cédric Touvrey , Eve Borel , Patrice N. Marche , Evelyne Jouvin-Marche , Serge M. Candéias et al.

Immunobiology, 2006, 211 (9), pp.741-751. ⟨10.1016/j.imbio.2006.04.001⟩

Article dans une revue istex hal-01948389v1

Reassignment of the murine 3′TRDD1 recombination signal sequence

S Touvrey , L. Cowell , E Lieberman , P. Marche , E. Jouvin-Marche et al.

Immunogenetics, 2006, 58 (11), pp.895-903. ⟨10.1007/s00251-006-0150-1⟩

Article dans une revue hal-01948384v1

Unrepaired cyclobutane pyrimidine dimers do not prevent proliferation of UV-B-irradiated cultured human fibroblasts.

Sophie Courdavault , Caroline Baudouin , Sylvie Sauvaigo , Stephane Mouret , Serge M. Candéias et al.

Photochemistry and Photobiology, 2004, 79 (2), pp.145-51

Article dans une revue hal-01949083v1

p53-dependent and p53-independent pathways for radiation-induced immature thymocyte differentiation

Serge M. Candéias , Stéphane Jean Charles Mancini , Cédric Touvrey , Eve Borel , Evelyne Marche et al.

Oncogene, 2004, 23 (10), pp.1922-1929. ⟨10.1038/sj.onc.1207320⟩

Article dans une revue hal-01948396v1

T lymphocytes potentiate murine dendritic cells to produce IL-12.

Alexandra Rizzitelli , Rolande Berthier , Véronique Collin , Serge M. Candéias , Patrice N. Marche

Journal of Immunology, 2002, 169 (8), pp.4237-45

Article dans une revue hal-01948399v1

TCRA gene rearrangement in immature thymocytes in absence of CD3, pre-TCR, and TCR signaling.

E. Mancini , Serge M. Candéias , P Di Santo , P. Ferrier , P. Marche et al.

Journal of Immunology, 2001, 167 (8), pp.4485-93

Article dans une revue hal-01948404v1

TCR alpha-chain repertoire in pTalpha-deficient mice is diverse and developmentally regulated: implications for pre-TCR functions and TCRA gene rearrangement.

E. Mancini , Serge M. Candéias , H Fehling , H von Boehmer , E Marche et al.

Journal of Immunology, 1999, 163 (11), pp.6053-9

Article dans une revue hal-01948407v1

Interleukin 7 receptor control of T cell receptor gamma gene rearrangement: role of receptor-associated chains and locus accessibility.

K Durum , Serge M. Candéias , H. Nakajima , L Leonard , A Baird et al.

Journal of Experimental Medicine, 1998, 188 (12), pp.2233-41

Article dans une revue hal-01949093v1

Differential chronology of TCRADV2 gene use by $\alpha$ and $\delta$ chains of the mouse TCR

Evelyne Jouvin-Marche , Catherine Aude-Garcia , Serge M. Candéias , Eve Borel , Soulef Hachemi-Rachedi et al.

European Journal of Immunology, 1998, 28 (3), pp.818-827. ⟨10.1002/(SICI)1521-4141(199803)28:03<818::AID-IMMU818>3.0.CO;2-0⟩

Article dans une revue hal-01949099v1

Use of TCR ADV gene segments by the δ chain is independent of their position and of CD3 expression

E Gallagher , C Candéias , M Martinon , Eve Borel , Marie Malissen et al.

European Journal of Immunology, 1998, 28 (11), pp.3878-3885. ⟨10.1002/(SICI)1521-4141(199811)28:11<3878::AID-IMMU3878>3.0.CO;2-C⟩

Article dans une revue hal-01949096v1

p53-dependent apoptosis and transcription of p21waf/cip1/sdi1 in SCID mice following gamma-irradiation.

Serge M. Candéias , K Durum , K Muegge

Biochimie, 1997, 79 (9-10), pp.607-12

Article dans une revue hal-01948420v1

IL-7 receptor and VDJ recombination: trophic versus mechanistic actions.

Serge M. Candéias , Kathrin Muegge , Scott K. Durum

Immunity, 1997, 6 (5), pp.501-8

Article dans une revue hal-01949113v1

IL-7 activates alpha4beta1 integrin in murine thymocytes.

S Kitazawa , M Muegge , R Badolato , J. Wang , W Fogler et al.

Journal of Immunology, 1997, 159 (5), pp.2259-64

Article dans une revue hal-01949103v1

Defective T-cell receptor gamma gene rearrangement in interleukin-7 receptor knockout mice.

Serge M. Candéias , J Peschon , K Muegge , S Durum

Immunology Letters, 1997, 57 (1-3), pp.9-14

Article dans une revue hal-01949109v1

Junctional diversity in signal joints from T cell receptor beta and delta loci via terminal deoxynucleotidyl transferase and exonucleolytic activity.

Serge M. Candéias , K Muegge , S Durum

Journal of Experimental Medicine, 1996, 184 (5), pp.1919-26

Article dans une revue hal-01949115v1

A novel putative helicase produced in early murine lymphocytes.

S. Jarvis , T Geiman , S Vila-Storm , O Osipovich , U Akella et al.

Gene, 1996, 169 (2), pp.203-7

Article dans une revue hal-01949117v1

Expression of FcγRIII defines distinct subpopulations of fetal liver B cell and myeloid precursors

U Carlsson , Serge M. Candéias , Uwe Staerz , Gordon Keller , Leif Carlsson

European Journal of Immunology, 1995, 25 (8), pp.2308-2317. ⟨10.1002/eji.1830250829⟩

Article dans une revue hal-01949118v1

T cell receptor Vβ8.2 gene germ-line transcription: An early event of lymphocyte differentiation

R Candéias , Richard Hardy , Yue Sheng Li , Uwe Staerz , Serge M. Candéias

European Journal of Immunology, 1994, 24 (12), pp.3073-3081. ⟨10.1002/eji.1830241224⟩

Article dans une revue hal-01949119v1

NF-X, a transcription factor implicated in MHC class II gene regulation.

V Kouskoff , R Mantovani , Serge M. Candéias , A Staub , B Lisowska-Grospierre et al.

Journal of Immunology, 1991, 146 (9), pp.3197-204

Article dans une revue hal-01949125v1

A special repertoire of $\alpha$:$\beta$ T cells in neonatal mice.

M. Bogue , Serge M. Candéias , C. Benoist , D. Mathis

EMBO Journal, 1991, 10 (12), pp.3647-3654

Article dans une revue hal-01949121v1

Islet-specific T-cell clones from nonobese diabetic mice express heterogeneous T-cell receptors.

Serge M. Candéias , C Candéias , K Katz , C. Benoist , D Mathis et al.

Proceedings of the National Academy of Sciences of the United States of America, 1991, 88 (14), pp.6167-70

Article dans une revue hal-01949123v1

The V$_\beta$ 17$^+$ T cell repertoire: skewed J$\beta$ usage after thymic selection; dissimilar CDR3s in CD4$^+$ versus CD8$^+$ cells.

Serge M. Candéias , Caroline Waltzinger , Christophe Benoist , Diane Mathis

Journal of Experimental Medicine, 1991, 174 (5), pp.989-1000

Article dans une revue hal-01949122v1

An enhancer factor defect in a mutant Burkitt lymphoma cell line.

Werner Koch , Serge M. Candéias , John Guardiola , Roberto Accolla , Christophe Benoist et al.

Journal of Experimental Medicine, 1988, 167 (6), pp.1781-90

Article dans une revue hal-01949126v1

Influence of radiation quality and energy on radiation-induced inflammation in primary human cells.

Serge M. Candéias , Clément Rouichi , Elisabeth Chartier-Garcia , Isabelle Testard

49th European Radiation Research Society meeting (ERRS 2025), Sep 2025, Bruxelle, Belgium

Communication dans un congrès hal-05517425v1

High dose radiation induces an early and transient ATM-dependent activation of NF-kB in endothelial cells.

Serge M. Candéias

JOINT WORKSHOP QST-CEA-ASNR 2025, Mar 2025, Fontenay aux Roses, France

Communication dans un congrès hal-05517485v1

High dose radiation induce an early and transient ATM-dependent activation of NF-κB in endothelial cells

Clément Rouichi , Elisabeth Chartier-Garcia , Jean-Luc Ravanat , Isabelle Testard , Serge M. Candéias

48th European Radiation Research Society Meeting (ERRS2024), CESAM and GreenUPorto from the Faculty of Sciences of the University of Porto., Sep 2024, Aveiro- University of Aveiro, Portugal

Communication dans un congrès hal-05117152v1

Radiation-induced direct and bystander expression of inflammatory mediators depends on cell type, radiation dose, dose delivery and LET

Isabelle Testard , Elisabeth Chartier-Garcia , Clément Rouichi , Milagrosa Lopez Riego , Lovisa Lundholm et al.

48th European Radiation Research Society Meeting (ERRS2024), Sep 2024, Aveiro- University of Aveiro, Portugal

Communication dans un congrès hal-05131611v1

Consequences of radiation exposure on immune cells and functions

Serge M. Candéias

invited seminar of the National Cancer Institute, Division of Cancer Epidemiology and Genetics, Radiation Epidemiology Branch, Bethesda, MD (USA), Jun 2022, Online, France

Communication dans un congrès hal-05133548v1

Mécanismes pour l’induction d’une réponse inflammatoire par de fortes doses de radiations

Clément Rouichi , Elisabeth Chartier-Garcia , Jean-Luc Ravanat , Isabelle Testard , Serge M. Candéias

1er Congrès de la Société Française de Biologie des Radiations (SFBR), Nov 2022, Saint-Raphaël- Centre IGESA, France

Communication dans un congrès hal-05117296v1

Long-term immuno-modulatory effects of ionizing radiation

Serge M. Candéias

46th Annual Meeting of the European Radiation Research Society (ERRS-2021), Nov 2021, Caen, Université de Caen-Normandie(Présentiel), France

Communication dans un congrès hal-04511538v1

T lymphocyte homeostasis with age and in response to radiation

Serge M. Candéias

annual GREWIS-alpha (Genetic risks and anti-inflammatory effects of dense-ionizing α-radiation) meeting, Nov 2021, Online, France

Communication dans un congrès hal-05131678v1

The immune response to low dose radiation

Serge M. Candéias

Audition du Comité des Académies Nationales de Sciences, Ingénierie et Médecine (USA) chargé du développement d’une stratégie à long terme pour l’étude des effets des faibles doses de radiation., Nov 2021, Online, France

Communication dans un congrès hal-05131731v1

Long-term immunomodulatory effects of radiation exposure

Serge M. Candéias

46th Annual Meeting of the European Radiation Research Society (ERRS 2021), Nov 2021, Caen, France

Communication dans un congrès hal-03578728v1

Radiation does not impair genetic stability during TCR gene rearrangement in mice

Serge M. Candéias

12th International Symposium on Chromosomal Aberrations, Aug 2019, Manchester, United Kingdom

Communication dans un congrès hal-05123286v1

Dynamics of the antigenic T cell receptor repertoire in response to radiation exposure and ageing

Serge M. Candéias

International workshop on clonal hematopoiesis and radiation-associated diseases, Jan 2019, Hiroshima, Japan

Communication dans un congrès hal-05123317v1

Low dose radiation effects on the homeostasis and activation of immune cells

Serge M. Candéias

16th International Congress of Radiation Research (ICRR- 2019), Aug 2019, Manchester, United Kingdom

Communication dans un congrès hal-05123258v1

Effects of nanoparticles on murine macrophages

Mireille Chevallet , Catherine Aude-Garcia , Cécile Lelong , Serge M. Candéias , Sylvie Luche et al.

Nanosafe2010: International Conference on Safe Production and Use of Nanomaterials 16-18 November 2010, Grenoble, France, Nov 2010, Grenoble, France. pp.12034, ⟨10.1088/1742-6596/304/1/012034⟩

Communication dans un congrès hal-00607201v1

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