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Soraya Mezouar

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**FORMATION** - 2022. Maitre de Conférences**, Section 65 - 2020. Habilitation à diriger les recherches**, Caractérisation des mécanismes immunitaires impliqués dans les pathologies inflammatoires stériles et infectieuses. Défendue le 28 septembre 2020 – Aix-Marseille Univ – Faculté des Sciences Médicales et Paramédicales, Marseille - 2019. Qualification Maitre de Conférences**, Section 65, N°19265323510 - 2016. Formation d’expérimentation en laboratoire NSB3**, Marseille, France - 2015. Doctorat.** Implication des plaquettes dans l’inflammation, la thrombose et le cancer, directeur de thèse Pr. C. Dubois. Défendue le 3 décembre 2015 – Aix-Marseille Univ – Faculté de Médecine, Marseille - 2014. Modèles animaux d’AVC- Chirurgie vasculaire chez les rongeurs**, Cyceron, Caen - 2013. Imagerie des petits animaux - Spécialisation chirurgie animale**, CNRS, Marseille - 2012. Formation spécialisée en expérimentation animale (niveau 1), Faculté de Pharmacie, Marseille - 2011. Master Pathologie Humaine, Université de la Méditerranée**, Marseille, France - 2009. Licence, Physiopathologie et génie génétique, Université de Provence**, Marseille, France **ACTIVITE DE RECHERCHE** **Expérience de recherche** * -2022-aujourd'hui. Maitre de Conférence. ADES UMR 7268, Genglobe - 2020-2022. Responsable de l’équipe biologie-pharmacologie *in vivo* et *in vitro.* Genoscience Pharma, *Développement de médicaments inhibiteurs de l’autophagie dans les maladies infectieuses, auto-immunes et le cancer* - 2016-2022. Post-doctorat puis chercheur associé. MEPHI, Aix-Marseille Univ, IRD, AP-HM, IHU Mediterranean Infection, *Caractérisation des mécanismes immunitaires impliqués dans les pathologies inflammatoires infectieuses,* supervision Pr. J.L Mege - 2011-2015. Doctorat en science. Aix-Marseille Univ, INSERM UMR 1076, *Implication des plaquettes dans l’inflammation, la thrombose et le cancer,* supervision Pr. C. Dubois - 2009-2011. Master Pathologie Humaine (M2) Aix-Marseille Univ, INSERM UMR 911, *Implication de l’activation plaquettaire dans le cancer, la croissance tumorale et les métastases in vivo,* supervision Pr. C. Dubois. (M1) Aix-Marseille Univ, INSERM UMR 911*, Caractérisation moléculaire du glioblastome par immunohistochimie,* supervision Dr. C. Colin** **Impact scientifique** - **H index :** 25 - **Citations** : 2530 depuis 2012 (dont 2047 depuis 2017) - **Distinctions et diffusions scientifiques** **Prix, bourse et société scientifique** - 2021. ANR**, co-investigateur, Sensibilisation immunitaire fongique : un centre de diagnostic pour l’exosome fongique, la susceptibilité individuelle et la fonction pulmonaire à long terme, FUNGIPLEX, investigateur: P. Demoly - 2021. Projet d’échange de recherche SCORE**, Fédération internationale des associations d’étudiants en médecine, Programme d’échanges internationaux d’étudiants en médecine - 2021-2024. Bourse de doctorat régionale,** Rôle des médicaments modulateurs d’autophagie dans l’infection par le SARS-CoV-2, Unité MEPHI (académique) et Genoscience Pharma (industrie) - 2021. ANR**, co-investigateur, Organoïdes du côlon humain comme outil d’étude des infections par les variants du SARS-CoV-2, ORGANOVIR, investigateur: H. Lelouard, CIML - 2020. ANR**, co-investigateur, Evolution de la réponse immune au cours de l’infection au COVID-19: stratification des patients, IMMUNO-COVID, investigateur: J. Vitte - 2020- .** Membre du *Journal of Leukocyte Biology* - 2020.** Winter school, *European Academy of Allergy & Clinical Immunology*, Chamonix, France - 2019- . Membre de *European Academy of Allergy & Clinical Immunology* - 2018- . Membre de la *Société Française d’Immunologie* - 2018-2020. Bourse post-doctorale, Fondation Méditerranée infection - 2018. Meilleur présentation orale, *Société Française d’Immunologie*, Paris, France - 2016-2018. Bourse post-doctorale, Fondation Recherche Médicale - 2015. “Young investigator award”, *Eurothrombosis*, Côme, Italie - 2015. Bourse de voyage, École Doctorale des Sciences de la Vie et de la Santé *-* ED 62 - 2015. « Young investigator award », *International Society of Thrombosis and Hemostasis*, Toronto, Canada - 2014-2015. Bourse doctorale, Groupe Francophone Thrombose et Cancer - 2011-2014. Bourse doctorale, Ministère Français de la recherche** **Activité d’expertise scientifique** - 2021. Expert HCERES**, Evaluation d’Ecole Doctorale (Nantes 04/2021 et Bordeaux 09/2021) - 2020-2021.** **Expert DIM1HEALTH** - 2016-2021.** **Activité de reviewing**, *Scientific Report*, *Blood Advances*, *Cell Communication and Signaling*, *Journal of Immunology*, *Frontiers in Microbiology*, *Frontiers in Immunology*, *Frontiers in Oncology*, *Microbial Pathogenesis, Viruses, Pathogens* **Diffusion de la culture scientifique** - 2023.**Participation à la deuxième rencontre avec les acteurs du monde socio-économique** (étudiants de Master 1 & de 4° année de pharmacie filière industrie), Faculté de Pharmacie, Marseille- 2022. - 2022. Participation à la première rencontre avec les acteurs du monde socio-économique** (étudiants de Master 1 & de 4° année de pharmacie filière industrie), Faculté de Pharmacie, Marseille - **2020.** **Webinar live**, *Signature cellulaire et moléculaire de la COVID-19,* collaboration avec la Faculté Hassan II, Casablanca, Maroc - **2017-2021.** **Participation à DECLICS** (Développer les Échanges entre Chercheurs et Lycéens pour les Intéresser à la Construction des Savoirs), une des actions du Cercle FSER, la branche Sciences et Société de la Fondation Schlumberger pour l’Éducation et la Recherche. Déclics consiste à faire intervenir des équipes de recherche dans les lycées pour échanger directement avec des élèves en petits groupes - **2013.** **Participation à la journée de la recherche**, Faculté de Pharmacie, Marseille **ACTIVITE D'ENCADREMENT** - 8 Co-encadrement de thèses de science (PhD) soutenues - 1 encadrement de thèse de science (PhD), en cours - 20 mémoires de Master Recherche soutenus **RESPONSABILITE** - Responsable Master Medical Bioengineering, Faculté des Sciences Médicales et Paramédicales de Marseille (Wuhan, Chine) - Responsable Master Biologie Santé Parcours Oncologie en Alternance, Faculté des Sciences Médicales et Paramédicales de Marseille (Wuhan, Chine) - Co-Supervision de l'UE libre Initiation de la Recherche, Faculté de Médecine - Co-Supervision de l'UE Réponse de l'hôte, Master Biologie Santé

Publications

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Disruption of the Expression of the Placental Clock and Melatonin Genes in Preeclampsia

Aïssatou Bailo Diallo , Benjamin Coiffard , Raoul Desbriere , Maria Katsogiannou , Xavier Donato
International Journal of Molecular Sciences, 2023, 24 (3), pp.2363. ⟨10.3390/ijms24032363⟩
Journal articles hal-04082229v1

Modulation of the E-cadherin in human cells infected in vitro with Coxiella burnetii

Ikram Omar Osman , Soraya Mezouar , Djamal Brahim-Belhaouari , Jean-Louis Mege , Christian Albert Devaux
PLoS ONE, 2023, 18 (6), pp.e0285577. ⟨10.1371/journal.pone.0285577⟩
Journal articles hal-04125807v1
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The DNA-binding induced (de)AMPylation activity of a Coxiella burnetii Fic enzyme targets Histone H3

Dorothea Höpfner , Adam Cichy , Vivian Pogenberg , Christoph Krisp , Soraya Mezouar
Communications Biology, 2023, 6 (1), pp.1124. ⟨10.1038/s42003-023-05494-7⟩
Journal articles hal-04275822v1
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Infection and Persistence of Coxiella burnetii Clinical Isolate in the Placental Environment

Sandra Madariaga Zarza , Muriel Militello , Laetitia Gay , Anthony Levasseur , Hubert Lepidi
International Journal of Molecular Sciences, 2023, 24 (2), pp.1209. ⟨10.3390/ijms24021209⟩
Journal articles hal-04045432v1
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Mycobacterium tuberculosis Resides in Macrophages in Laryngeal Tuberculosis: A Case Report

Wafaa Achache , Mahmoud A Boualam , Nadim Cassir , Clémence Mimari , Delphine Poitrenaud
Pathogens, 2023, 12 (12), pp.1413. ⟨10.3390/pathogens12121413⟩
Journal articles hal-04509468v1
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Update on Autophagy Inhibitors in Cancer: Opening up to a Therapeutic Combination with Immune Checkpoint Inhibitors

Eloïne Bestion , Eric Raymond , Soraya Mezouar , Philippe Halfon
Cells, 2023, 12 (13), pp.1702. ⟨10.3390/cells12131702⟩
Journal articles hal-04482335v1
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The DNA-binding induced (de)AMPylation activity of a Coxiella burnetii Fic enzyme targets Histone H3

Dorothea Höpfner , Adam Cichy , Vivian Pogenberg , Christoph Krisp , Soraya Mezouar
Communications Biology, 2023, 6 (1), pp.1124. ⟨10.1038/s42003-023-05494-7⟩
Journal articles hal-04537727v1
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Gut microbiota in SLE: from animal models to clinical evidence and pharmacological perspectives

Eya Toumi , Soraya Mezouar , Anne Plauzolles , Laurent Chiche , Nathalie Bardin
Lupus science & medicine, 2023, 10 (1), pp.e000776. ⟨10.1136/lupus-2022-000776⟩
Journal articles hal-04082348v1

Role of Vγ9vδ2 T lymphocytes in infectious diseases

Laetitia Gay , Soraya Mezouar , Carla Cano , Paul Frohna , Loui Madakamutil
Frontiers in Immunology, 2022, 13, ⟨10.3389/fimmu.2022.928441⟩
Journal articles hal-04081615v1

Whipple's disease and Tropheryma whipplei infections: from bench to bedside

Asma Boumaza , Eya Ben Azzouz , Jeffrey Arrindell , Hubert Lepidi , Soraya Mezouar
The Lancet Infectious Diseases, 2022, 22 (10), pp.e280-e291. ⟨10.1016/S1473-3099(22)00128-1⟩
Journal articles hal-03985906v1
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GNS561 Exhibits Potent Antiviral Activity against SARS-CoV-2 through Autophagy Inhibition

Eloïne Bestion , Keivan Zandi , Sandrine Belouzard , Julien Andreani , Hubert Lepidi
Viruses, 2022, 14 (1), pp.132. ⟨10.3390/v14010132⟩
Journal articles hal-03663720v1
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A Non-Invasive Neonatal Signature Predicts Later Development of Atopic Diseases

Youssouf Sereme , Moïse Michel , Soraya Mezouar , Cheick Oumar Guindo , Lanceï Kaba
Journal of Clinical Medicine, 2022, 11 (10), pp.2749. ⟨10.3390/jcm11102749⟩
Journal articles hal-03754547v1
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RadA, a Key Gene of the Circadian Rhythm of Escherichia coli

Aissatou Bailo Diallo , Soraya Mezouar , Asma Boumaza , Oksana Fiammingo , Benjamin Coiffard
International Journal of Molecular Sciences, 2022, 23 (11), pp.6136. ⟨10.3390/ijms23116136⟩
Journal articles hal-03684665v1
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Macrophages and γδ T cells interplay during SARS-CoV-2 variants infection

Perla Abou Atmeh , Laetitia Gay , Anthony Levasseur , Bernard La Scola , Daniel Olive
Frontiers in Immunology, 2022, 13, pp.1078741. ⟨10.3389/fimmu.2022.1078741⟩
Journal articles hal-03951960v1
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Congenital Infection of Severe Acute Respiratory Syndrome Coronavirus 2 With Intrauterine Fetal Death: A Clinicopathological Study With Molecular Analysis

Emmanuelle Lesieur , Julia Torrents , Frédéric Fina , Christine Zandotti , Julie Blanc
Clinical Infectious Diseases, 2022, 75 (1), pp.E1092-E1100. ⟨10.1093/cid/ciab840⟩
Journal articles hal-03665773v1
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Gut microbiota in systemic lupus erythematosus patients and lupus mouse model: a cross species comparative analysis for biomarker discovery

Eya Toumi , Benoit Goutorbe , Anne Plauzolles , Marion Bonnet , Soraya Mezouar
Frontiers in Immunology, 2022, 13, ⟨10.3389/fimmu.2022.943241⟩
Journal articles hal-03941998v1

GNS561, a clinical-stage PPT1 inhibitor, is efficient against hepatocellular carcinoma via modulation of lysosomal functions

Sonia Brun , Eloïne Bestion , Eric Raymond , Firas Bassissi , Zuzana Macek Jilkova
Autophagy, 2022, 18 (3), pp.678-694. ⟨10.1080/15548627.2021.1988357⟩
Journal articles hal-03677289v1

Selected recent advances in understanding the role of human mast cells in health and disease

Francesca Levi-Schaffer , Bernhard Gibbs , Jenny Hallgren , Carlo Pucillo , Frank Redegeld
Journal of Allergy and Clinical Immunology, 2022, 149 (6), pp.1833-1844. ⟨10.1016/j.jaci.2022.01.030⟩
Journal articles hal-04106566v1
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BTN3A Targeting Vγ9Vδ2 T Cells Antimicrobial Activity Against Coxiella burnetii-Infected Cells

Laetitia Gay , Soraya Mezouar , Carla Cano , Etienne Foucher , Mélanie Gabriac
Frontiers in Immunology, 2022, 13, ⟨10.3389/fimmu.2022.915244⟩
Journal articles hal-03823828v1
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First-In-Human Effects of PPT1 Inhibition Using the Oral Treatment with GNS561/Ezurpimtrostat in Patients with Primary and Secondary Liver Cancers

James Harding , Ahmad Awada , Gael Roth , Thomas Decaens , Philippe Merle
Liver Cancer, 2022, 11 (3), pp.268-277. ⟨10.1159/000522418⟩
Journal articles hal-04161118v1
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Sexual Dimorphism and Gender in Infectious Diseases

Laetitia Gay , Cléa Melenotte , Ines Lakbar , Soraya Mezouar , Christian Devaux
Frontiers in Immunology, 2021, 12, ⟨10.3389/fimmu.2021.698121⟩
Journal articles hal-03300038v1
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Stool Serology: Development of a Non-Invasive Immunological Method for the Detection of Enterovirus-Specific Antibodies in Congo Gorilla Faeces

Youssouf Sereme , Sandra Madariaga Zarza , Hacène Medkour , Inestin Amona , Florence Fenollar
Microorganisms, 2021, 9 (4), pp.810. ⟨10.3390/microorganisms9040810⟩
Journal articles hal-03279623v1
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Daytime variation in SARS-CoV-2 infection and cytokine production

Aïssatou Bailo Diallo , Laetitia Gay , Benjamin Coiffard , Marc Leone , Soraya Mezouar
Microbial Pathogenesis, 2021, 158, pp.105067. ⟨10.1016/j.micpath.2021.105067⟩
Journal articles hal-03428424v1

Monocytes and macrophages, targets of SARS-CoV-2: the clue for Covid-19 immunoparalysis

Asma Boumaza , Laetitia Gay , Soraya Mezouar , Eloïne Bestion , Aïssatou Bailo Diallo
Journal of Infectious Diseases, 2021, ⟨10.1093/infdis/jiab044⟩
Journal articles hal-03152762v1
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A Tangled Threesome: Circadian Rhythm, Body Temperature Variations, and the Immune System

Benjamin Coiffard , Aïssatou Bailo Diallo , Soraya Mezouar , Marc Leone , Jean-Louis Mege
Biology, 2021, 10 (1), pp.65. ⟨10.3390/biology10010065⟩
Journal articles hal-03216153v1

IgG removal significantly enhances detection of microarray allergen‐specific IgE reactivity in patients' serum

Youssouf Sereme , Natacha Casanovas , Moïse Michel , Audrey Martin‐blondel , Farid Mankouri
Allergy, 2021, 76 (1), pp.395-398. ⟨10.1111/all.14536⟩
Journal articles hal-03599645v1

Tumor Necrosis Factor Inhibitors Exacerbate Whipple’s Disease by Reprogramming Macrophage and Inducing Apoptosis

Asma Boumaza , Soraya Mezouar , Matthieu Bardou , Didier Raoult , Jean-Louis Mège
Frontiers in Immunology, 2021, 12, ⟨10.3389/fimmu.2021.667357⟩
Journal articles hal-03281588v1

Impact of Sex Hormones on Macrophage Responses to Coxiella burnetii

Laetitia Gay , Cléa Melenotte , Alexandre Lopez , Benoit Desnues , Didier Raoult
Frontiers in Immunology, 2021, 12, ⟨10.3389/fimmu.2021.705088⟩
Journal articles hal-03520015v1
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Presence of SARS-CoV-2 in a Cornea Transplant

Myriem Otmani Idrissi , Jean-Pierre Baudoin , Anne-Line Chateau , Sarah Aherfi , Marielle Bedotto-Buffet
Pathogens, 2021, 10 (8), pp.934. ⟨10.3390/pathogens10080934⟩
Journal articles hal-03329562v1
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GNS561, a New Autophagy Inhibitor Active against Cancer Stem Cells in Hepatocellular Carcinoma and Hepatic Metastasis from Colorectal Cancer

Sonia Brun , Jean-Marc Pascussi , Elena Patricia Gifu , Eloïne Bestion , Zuzana Macek-Jilkova
American Journal of Cancer, 2021, 12 (18), pp.5432-5438. ⟨10.7150/jca.58533⟩
Journal articles hal-03326462v1
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From Coxiella burnetii Infection to Pregnancy Complications: Key Role of the Immune Response of Placental Cells

Sandra Madariaga Zarza , Soraya Mezouar , Jean-Louis Mege
Pathogens, 2021, 10 (5), pp.627. ⟨10.3390/pathogens10050627⟩
Journal articles hal-03308215v1
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P2RY12-Inhibitors Reduce Cancer-Associated Thrombosis and Tumor Growth in Pancreatic Cancers

Ana Luisa Palacios-Acedo , Soraya Mezouar , Diane Mège , Lydie Crescence , Christophe Dubois
Frontiers in Oncology, 2021, 11, ⟨10.3389/fonc.2021.704945⟩
Journal articles hal-03653453v1
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Placental macrophages: Origin, heterogeneity, function and role in pregnancy-associated infections

Soraya Mezouar , Maria Katsogiannou , Amira Ben Amara , Florence Bretelle , Jean-Louis Mege
Placenta, 2021, 103, pp.94-103. ⟨10.1016/j.placenta.2020.10.017⟩
Journal articles hal-03216137v1

Bacterial infection and non-Hodgkin’s lymphoma

Cléa Melenotte , Soraya Mezouar , Jean-Louis Mège , Jean-Pierre Gorvel , Guido Kroemer
Critical Reviews in Microbiology, 2020, 46 (3), pp.270-287. ⟨10.1080/1040841X.2020.1760786⟩
Journal articles hal-02997350v1

A Granulocytic Signature Identifies COVID-19 and Its Severity

Joana Vitte , Aïssatou Bailo Diallo , Asma Boumaza , Alexandre Lopez , Moïse Michel
Journal of Infectious Diseases, 2020, 222 (12), pp.1985-1996. ⟨10.1093/infdis/jiaa591⟩
Journal articles hal-03150816v1
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T-Bet Controls Susceptibility of Mice to Coxiella burnetii Infection

Soraya Mezouar , Hubert Lepidi , Ikram Omar Osman , Jean-Pierre Gorvel , Didier Raoult
Frontiers in Microbiology, 2020, 11, ⟨10.3389/fmicb.2020.01546⟩
Journal articles hal-02998321v1
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For Whom the Clock Ticks: Clinical Chronobiology for Infectious Diseases

Aissatou Bailo Diallo , Benjamin Coiffard , Marc Leone , Soraya Mezouar , Jean-Louis Mege
Frontiers in Immunology, 2020, 11, ⟨10.3389/fimmu.2020.01457⟩
Journal articles hal-03149943v1

Changing the paradigm of IFN‐γ at the interface between innate and adaptive immunity: Macrophage‐derived IFN‐γ

Soraya Mezouar , Jean‐louis Mege
Journal of Leukocyte Biology, 2020, ⟨10.1002/JLB.4MIR0420-619RR⟩
Journal articles hal-02868444v1
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Immune Modulation as a Therapeutic Option During the SARS-CoV-2 Outbreak: The Case for Antimalarial Aminoquinolines

Joana Vitte , Moise Michel , Soraya Mezouar , Aissatou Bailo Diallo , Asma Boumaza
Frontiers in Immunology, 2020, 11, ⟨10.3389/fimmu.2020.02159⟩
Journal articles hal-03149722v1
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The E-Cadherin Cleavage Associated to Pathogenic Bacteria Infections Can Favor Bacterial Invasion and Transmigration, Dysregulation of the Immune Response and Cancer Induction in Humans

Christian Devaux , Soraya Mezouar , Jean-Louis Mege
Frontiers in Microbiology, 2019, 10, ⟨10.3389/fmicb.2019.02598⟩
Journal articles hal-02417835v1
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Tumor Necrosis Factor-Alpha Antagonist Interferes With the Formation of Granulomatous Multinucleated Giant Cells: New Insights Into Mycobacterium tuberculosis Infection

Soraya Mezouar , Issa Diarra , Jean Roudier , Benoit Desnues , Jean-Louis Mege
Frontiers in Immunology, 2019, 10, ⟨10.3389/fimmu.2019.01947⟩
Journal articles hal-02471127v1
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High Concentrations of Serum Soluble E-Cadherin in Patients With Q Fever

Soraya Mezouar , Ikram Omar Osman , Clea Melenotte , Camélia Slimani , Céline Chartier
Frontiers in Cellular and Infection Microbiology, 2019, 9, ⟨10.3389/fcimb.2019.00219⟩
Journal articles hal-02417843v1

A Fast and Reliable Method to Isolate Human Placental Macrophages

Soraya Mezouar , Amira Ben Amara , Céline Chartier , Laurent Gorvel , Jean-Louis Mege
Current Protocols in Immunology, 2019, 125 (1), pp.e77. ⟨10.1002/cpim.77⟩
Journal articles hal-02202782v1
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Pru p 7 sensitization is a predominant cause of severe, cypress pollen‐associated peach allergy

Caroline Klingebiel , Yannick Chantran , Rihane Arif‐lusson , Angelica Ehrenberg , Jonas Östling
Clinical and Experimental Allergy, 2019, 49 (4), pp.526-536. ⟨10.1111/cea.13345⟩
Journal articles hal-02202464v1

Methanogenic Archaea: Emerging Partners in the Field of Allergic Diseases

Youssouf Sereme , Soraya Mezouar , Ghiles Grine , Jean-Louis Mege , Michel Drancourt
Clinical Reviews in Allergy and Immunology, 2019, 57 (3), pp.456-466. ⟨10.1007/s12016-019-08766-5⟩
Journal articles hal-02458066v1
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A transcriptional signature associated with non-Hodgkin lymphoma in the blood of patients with Q fever

Clea Melenotte , Soraya Mezouar , Amira Ben Amara , Simon Benatti , Jacques Chiaroni
PLoS ONE, 2019, 14 (6), pp.e0217542. ⟨10.1371/journal.pone.0217542⟩
Journal articles hal-02165970v1
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Progenitor mast cells and tryptase in Q fever

Soraya Mezouar , Victor Morel , Laury Leveille , Noémie Resseguier , Céline Chartier
Comparative Immunology, Microbiology and Infectious Diseases, 2019, 64, pp.159-162. ⟨10.1016/j.cimid.2019.03.011⟩
Journal articles hal-02158738v1

Paired acute‐baseline serum tryptase levels in perioperative anaphylaxis: An observational study

Joana Vitte , Laurent Amadei , Marion Gouitaa , Soraya Mezouar , Laurent Zieleskiewicz
Journal articles hal-02159236v1
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Full-Term Human Placental Macrophages Eliminate Coxiella burnetii Through an IFN-γ Autocrine Loop

Soraya Mezouar , Imene Benammar , Asma Boumaza , Aïssatou Bailo Diallo , Céline Chartier
Frontiers in Microbiology, 2019, 10, ⟨10.3389/fmicb.2019.02434⟩
Journal articles hal-02458052v1
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Mast Cell Cytonemes as a Defense Mechanism against Coxiella burnetii

Soraya Mezouar , Joana Vitte , Laurent Gorvel , Amira Ben Amara , Benoit Desnues
mBio, 2019, 10 (2), pii: e02669-18. ⟨10.1128/mBio.02669-18⟩
Journal articles hal-02262531v1

Circadian Rhythm Disruption and Sepsis in Severe Trauma Patients

Benjamin Coiffard , Aissatou Diallo , Aurélien Culver , Soraya Mezouar , Emmanuelle Hammad
Shock, 2019, 52 (1), pp.29-36. ⟨10.1097/SHK.0000000000001241⟩
Journal articles hal-02479798v1

Cigarette smoke extract interferes with placenta macrophage functions: A new mechanism to compromise placenta functions?

Rym Belhareth , Soraya Mezouar , Amira Ben Amara , Celine Chartier , Eya Ben Azzouz
Reproductive Toxicology, 2018, 78, pp.120-129. ⟨10.1016/j.reprotox.2018.04.009⟩
Journal articles hal-01858901v1

Tropheryma whipplei Increases Expression of Human Leukocyte Antigen-G on Monocytes to Reduce Tumor Necrosis Factor and Promote Bacterial Replication

Eya Ben Azzouz , Asma Boumaza , Soraya Mezouar , Matthieu Bardou , Federico Carlini
Gastroenterology, 2018, 155 (5), pp.1553-1563. ⟨10.1053/j.gastro.2018.07.034⟩
Journal articles hal-01869370v1

Isolation of Human Placental Mast Cells

Soraya Mezouar , Amira Ben Amara , Joana Vitte , Jean-Louis Mege
Current Protocols in Cell Biology, 2018, 80 (1), pp.e52. ⟨10.1002/cpcb.52⟩
Journal articles hal-02444309v1

The Biomarkers of Venous Thromboembolism in Cancer Patients

Soraya Mezouar , Roxanne Darbousset , Corinne Frere , Philippe Debourdeau , Dominique Farge-Bancel
Oncologie, 2016, 18 (1), pp.17-21. ⟨10.1007/s10269-015-2579-z⟩
Journal articles hal-01453350v1
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Coxiella burnetii Induces Inflammatory Interferon-Like Signature in ă Plasmacytoid Dendritic Cells: A New Feature of Immune Response in Q ă Fever

Mignane B. Ka , Soraya Mezouar , Amira Ben Amara , Didier Raoult , Eric Ghigo
Frontiers in Cellular and Infection Microbiology, 2016, 6, pp.70. ⟨10.3389/fcimb.2016.00070⟩
Journal articles hal-01466866v1
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Role of platelets in cancer and cancer-associated thrombosis: Experimental and clinical evidences.

Soraya Mezouar , Corinne Frère , Roxane Darbousset , Diane Mege , Lydie Crescence
Thrombosis Research, 2016, 139, pp.65-76. ⟨10.1016/j.thromres.2016.01.006⟩
Journal articles hal-01455290v1

PO-34 - Optimal doses of tinzaparin to reduce both cancer-associated thrombosis and tumor growth in a mouse model of ectopic pancreatic syngeneic tumor

Panicot-Dubois Laurence , Soraya Mezouar , Léa Plantureux , Lydie Crescence , C Frère
Thrombosis Research, 2016, pp.S189
Journal articles hal-01467510v1
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Soluble Siglec-5 associates to PSGL-1 and displays anti-inflammatory activity

Marion Pepin , Soraya Mezouar , Julie Pegon , Vincent Muczynski , Frédéric Adam
Scientific Reports, 2016, 6 (1), pp.37953. ⟨10.1038/srep37953⟩
Journal articles hal-01455400v1

Microparticles and cancer thrombosis in animal models

Diane Mege , Soraya Mezouar , Francoise Dignat-George , Laurence Panicot-Dubois , Christophe Dubois
Thrombosis Research, 2016, 140 (Suppl 1), pp.S21-S26. ⟨10.1016/S0049-3848(16)30094-9⟩
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Optimal doses of tinzaparin to reduce both cancer-associated thrombosis and tumor growth in a mouse model of ectopic pancreatic syngeneic tumor

Corinne Frere , Soraya Mezouar , Léa Plantureux , Lydie Crescence , Laurence Panicot-Dubois
Journal of Thrombosis and Haemostasis, 2016, 14, pp.76-76. ⟨10.1016/S0049-3848(16)30167-0⟩
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Inhibition of platelet activation prevents the P-selectin and integrin-dependent accumulation of cancer cell microparticles and reduces tumor growth and metastasis in vivo

Soraya Mezouar , Roxane Darbousset , Francoise Dignat-George , Laurence Panicot‐dubois , Christophe Dubois
International Journal of Cancer, 2015, 136 (2), pp.462-475. ⟨10.1002/ijc.28997⟩
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Inhibition of platelet activation prevents the P‐selectin and integrin‐dependent accumulation of cancer cell microparticles and reduces tumor growth and metastasis in vivo

Soraya Mezouar , Roxane Darbousset , Françoise Dignat-George , Laurence Panicot-Dubois , Christophe Dubois
International Journal of Cancer, 2015, 136 (2), pp.462-475. ⟨10.1002/ijc.28997⟩
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Involvement of Platelet-Derived Microparticles in Tumor Progression and Thrombosis

Soraya Mezouar , Diane Mege , Roxane Darbousset , Dominique Farge , Philippe Debourdeau
Seminars in Oncology, 2014, 41 (3), pp.346-358. ⟨10.1053/j.seminoncol.2014.04.010⟩
Journal articles hal-03817751v1

Tissue factor–positive neutrophils bind to injured endothelial wall and initiate thrombus formation

Roxane Darbousset , Grace Thomas , Soraya Mezouar , Corinne Frère , Rénaté Bonier
Blood, 2012, 120 (10), pp.2133-2143. ⟨10.1182/blood-2012-06-437772⟩
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Tryptase determination as a complementary criterion for the diagnosis of perioperative anaphylaxis

Joana Vitte , Laurent Amadei , M. Gouitaa , Soraya Mezouar , Laurent Zieleskiewicz
Congress of the European-Academy-of-Allergy-and-Clinical-Immunology (EAACI), Jun 2019, Lisbon, Portugal. pp.9
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Pru P 7 is a major peach allergen associated with cypress pollen sensitization and increased risk of severe reactions

C. Klingebiel , Yannick Chantran , R. Arif-Lusson , A.E. Ehrenberg , J. Ostling
Congress of the European-Academy-of-Allergy-and-Clinical-Immunology (EAACI), 2019, Lisbon, Portugal. pp.46-47
Conference papers hal-02479752v1

IgG removal significantly enhances detection of microarray allergen-specific IgE reactivity in patients' serum

Youssouf Sereme , Pol-André Apoil , S. Pinchemel , C. Chartier , P Blanchard
Congress of the European-Academy-of-Allergy-and-Clinical-Immunology (EAACI), 2019, Lisbon, Portugal. pp.219-220
Conference papers hal-02479683v1

Microparticles and cancer thrombosis in animal models

Diane Mege , Soraya Mezouar , Francoise Dignat-George , Panicot-Dubois Laurence , Dubois Christophe
8TH INTERNATIONAL CONFERENCE ON THROMBOSIS AND HEMOSTASIS ISSUES IN CANCER (ICTHIC), Apr 2016, BERGAME, Italy
Conference papers hal-01464574v1